Correlative Memory Deficits, Aβ Elevation, and Amyloid Plaques in Transgenic Mice

Cited by (401)

Items 101–200 of 401

  1. Green tea epigallocatechin-3-gallate (EGCG) reduces β-amyloid mediated cognitive impairment and modulates tau pathology in Alzheimer transgenic mice
    Rezai-Zadeh, Kavon, Arendash, Gary W., Hou, Huayan, Fernandez, Frank, Jensen, Maren, Runfeldt, Melissa, Shytle, R. Douglas, Tan, Jun · 2008 · Brain Research
  2. Biology and Genetics of Prions Causing Neurodegeneration
    Prusiner, Stanley B. · 2013 · Annual Review of Genetics
  3. Synapses and Alzheimer's Disease
    Sheng, M., Sabatini, B. L., Sudhof, T. C. · 2012 · Cold Spring Harbor Perspectives in Biology
  4. Elusive roles for reactive astrocytes in neurodegenerative diseases
    Ben Haim, Lucile, Carrillo-de Sauvage, Maria-Angeles, Ceyzériat, Kelly, Escartin, Carole · 2015 · Frontiers in Cellular Neuroscience
  5. REVIEW: Curcumin and Alzheimer’s disease
    Hamaguchi, Tsuyoshi, Ono, Kenjiro, Yamada, Masahito · 2010 · CNS Neuroscience & Therapeutics
  6. Oligomerization of Alzheimer's β-Amyloid within Processes and Synapses of Cultured Neurons and Brain
    Takahashi, Reisuke H., Almeida, Claudia G., Kearney, Patrick F., Yu, Fangmin, Lin, Michael T., Milner, Teresa A., Gouras, Gunnar K. · 2004 · The Journal of Neuroscience
  7. Persistent improvement in synaptic and cognitive functions in an Alzheimer mouse model after rolipram treatment
    Gong, Bing, Vitolo, Ottavio V., Trinchese, Fabrizio, Liu, Shumin, Shelanski, Michael, Arancio, Ottavio · 2004 · Journal of Clinical Investigation
  8. The impact of systemic infection on the progression of neurodegenerative disease
    Perry, V. Hugh, Newman, Tracey A., Cunningham, Colm · 2003 · Nature Reviews Neuroscience
  9. Redox‐Active Metals, Oxidative Stress, and Alzheimer's Disease Pathology
    HUANG, XUDONG, MOIR, ROBERT D., TANZI, RUDOLPH E., BUSH, ASHLEY I., ROGERS, JACK T. · 2004 · Annals of the New York Academy of Sciences
  10. Reversible memory loss in a mouse transgenic model of Alzheimer’s disease
    Kotilinek, Linda A., Bacskai, Brian, Westerman, Marcus, Kawarabayashi, Takeshi, Younkin, Linda, Hyman, Bradley T., Younkin, Steven, Ashe, Karen H. · 2002 · The Journal of Neuroscience
  11. Nicotinamide Riboside Promotes Sir2 Silencing and Extends Lifespan via Nrk and Urh1/Pnp1/Meu1 Pathways to NAD+
    Belenky, Peter, Racette, Frances G., Bogan, Katrina L., McClure, Julie M., Smith, Jeffrey S., Brenner, Charles · 2007 · Cell
  12. Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance
    Zhao, Zhen, Sagare, Abhay P, Ma, Qingyi, Halliday, Matthew R, Kong, Pan, Kisler, Kassandra, Winkler, Ethan A, Ramanathan, Anita, Kanekiyo, Takahisa, Bu, Guojun et al. · 2015 · Nature Neuroscience
  13. N-methyl D-aspartate (NMDA) receptor antagonists and memantine treatment for Alzheimer’s disease, vascular dementia and Parkinson’s disease
    Olivares, David, K. Deshpande, Varun, Shi, Ying, K. Lahiri, Debomoy, H. Greig, Nigel, T. Rogers, Jack, Huang, Xudong · 2012 · Current Alzheimer Research
  14. SOD1 rescues cerebral endothelial dysfunction in mice overexpressing amyloid precursor protein
    Iadecola, Costantino, Zhang, Fangyi, Niwa, Kiyoshi, Eckman, Chris, Turner, Sherry K., Fischer, Elizabeth, Younkin, Steven, Borchelt, David R., Hsiao, Karen K., Carlson, George A. · 1999 · Nature Neuroscience
  15. A Mouse Model of Amyloid β Oligomers: Their Contribution to Synaptic Alteration, Abnormal Tau Phosphorylation, Glial Activation, and Neuronal Loss In Vivo
    Tomiyama, Takami, Matsuyama, Shogo, Iso, Hiroyuki, Umeda, Tomohiro, Takuma, Hiroshi, Ohnishi, Kiyouhisa, Ishibashi, Kenichi, Teraoka, Rie, Sakama, Naomi, Yamashita, Takenari et al. · 2010 · The Journal of Neuroscience
  16. Evidence for Seeding of β-Amyloid by Intracerebral Infusion of Alzheimer Brain Extracts in β-Amyloid Precursor Protein-Transgenic Mice
    Kane, Michael D., Lipinski, William J., Callahan, Michael J., Bian, Feng, Durham, Robert A., Schwarz, Roy D., Roher, Alex E., Walker, Lary C. · 2000 · The Journal of Neuroscience
  17. Aβ is targeted to the vasculature in a mouse model of hereditary cerebral hemorrhage with amyloidosis
    Herzig, Martin C, Winkler, David T, Burgermeister, Patrick, Pfeifer, Michelle, Kohler, Esther, Schmidt, Stephen D, Danner, Simone, Abramowski, Dorothee, Stürchler-Pierrat, Christine, Bürki, Kurt et al. · 2004 · Nature Neuroscience
  18. Lipopolysaccharide-induced-neuroinflammation increases intracellular accumulation of amyloid precursor protein and amyloid β peptide in APPswe transgenic mice
    Sheng, J · 2003 · Neurobiology of Disease
  19. Matrix Metalloproteinase-9 Degrades Amyloid-β Fibrils in Vitro and Compact Plaques in Situ
    Yan, Ping, Hu, Xiaoyan, Song, Haowei, Yin, Kejie, Bateman, Randall J., Cirrito, John R., Xiao, Qingli, Hsu, Fong F., Turk, John W., Xu, Jan et al. · 2006 · Journal of Biological Chemistry
  20. Amyloid β Induces the Morphological Neurodegenerative Triad of Spine Loss, Dendritic Simplification, and Neuritic Dystrophies through Calcineurin Activation
    Wu, Hai-Yan, Hudry, Eloise, Hashimoto, Tadafumi, Kuchibhotla, Kishore, Rozkalne, Anete, Fan, Zhanyun, Spires-Jones, Tara, Xie, Hong, Arbel-Ornath, Michal, Grosskreutz, Cynthia L. et al. · 2010 · The Journal of Neuroscience
  21. Early-onset and Robust Cerebral Microvascular Accumulation of Amyloid β-Protein in Transgenic Mice Expressing Low Levels of a Vasculotropic Dutch/Iowa Mutant Form of Amyloid β-Protein Precursor
    Davis, Judianne, Xu, Feng, Deane, Rashid, Romanov, Galina, Previti, Mary Lou, Zeigler, Kelly, Zlokovic, Berislav V., Van Nostrand, William E. · 2004 · Journal of Biological Chemistry
  22. Intraneuronal β-amyloid accumulation and synapse pathology in Alzheimer’s disease
    Gouras, Gunnar K., Tampellini, Davide, Takahashi, Reisuke H., Capetillo-Zarate, Estibaliz · 2010 · Acta Neuropathologica
  23. Review: sporadic cerebral amyloid angiopathy
    Attems, J., Jellinger, K., Thal, D. R., Van Nostrand, W. · 2011 · Neuropathology and Applied Neurobiology
  24. Il10 Deficiency Rebalances Innate Immunity to Mitigate Alzheimer-Like Pathology
    Guillot-Sestier, Marie-Victoire, Doty, Kevin R., Gate, David, Rodriguez, Javier, Leung, Brian P., Rezai-Zadeh, Kavon, Town, Terrence · 2015 · Neuron
  25. β-Site Amyloid Precursor Protein Cleaving Enzyme 1 Levels Become Elevated in Neurons around Amyloid Plaques: Implications for Alzheimer's Disease Pathogenesis
    Zhao, Jie, Fu, Yifan, Yasvoina, Marina, Shao, Peizhen, Hitt, Brian, O'Connor, Tracy, Logan, Sreemathi, Maus, Erika, Citron, Martin, Berry, Robert et al. · 2007 · The Journal of Neuroscience
  26. Interferon-γ and Tumor Necrosis Factor-α Regulate Amyloid-β Plaque Deposition and β-Secretase Expression in Swedish Mutant APP Transgenic Mice
    Yamamoto, Masaru, Kiyota, Tomomi, Horiba, Masahide, Buescher, James L., Walsh, Shannon M., Gendelman, Howard E., Ikezu, Tsuneya · 2007 · The American Journal of Pathology
  27. Aβ40 Inhibits Amyloid Deposition In Vivo
    Kim, Jungsu, Onstead, Luisa, Randle, Suzanne, Price, Robert, Smithson, Lisa, Zwizinski, Craig, Dickson, Dennis W., Golde, Todd, McGowan, Eileen · 2007 · The Journal of Neuroscience
  28. Absence of C1q Leads to Less Neuropathology in Transgenic Mouse Models of Alzheimer's Disease
    Fonseca, Maria Isabel, Zhou, Jun, Botto, Marina, Tenner, Andrea J. · 2004 · The Journal of Neuroscience
  29. Glutaminyl cyclase inhibition attenuates pyroglutamate Aβ and Alzheimer's disease–like pathology
    Schilling, Stephan, Zeitschel, Ulrike, Hoffmann, Torsten, Heiser, Ulrich, Francke, Mike, Kehlen, Astrid, Holzer, Max, Hutter-Paier, Birgit, Prokesch, Manuela, Windisch, Manfred et al. · 2008 · Nature Medicine
  30. Progressive, age-related behavioral impairments in transgenic mice carrying both mutant amyloid precursor protein and presenilin-1 transgenes
    Arendash, Gary W., King, David L., Gordon, Marcia N., Morgan, Dave, Hatcher, Jaime M., Hope, Caroline E., Diamond, David M. · 2001 · Brain Research
  31. Nicotinamide riboside restores cognition through an upregulation of proliferator-activated receptor-γ coactivator 1α regulated β-secretase 1 degradation and mitochondrial gene expression in Alzheimer's mouse models
    Gong, Bing, Pan, Yong, Vempati, Prashant, Zhao, Wei, Knable, Lindsay, Ho, Lap, Wang, Jun, Sastre, Magdalena, Ono, Kenjiro, Sauve, Anthony A. et al. · 2013 · Neurobiology of Aging
  32. Blood—Brain Barrier Permeability Precedes Senile Plaque Formation in an Alzheimer Disease Model
    UJIIE, MAKI, DICKSTEIN, DARA L., CARLOW, DOUGLAS A., JEFFERIES, WILFRED A. · 2003 · Microcirculation
  33. Abnormal interaction of VDAC1 with amyloid beta and phosphorylated tau causes mitochondrial dysfunction in Alzheimer’s disease
    Manczak, M., Reddy, P. H. · 2012 · Human Molecular Genetics
  34. Association of Microglia with Amyloid Plaques in Brains of APP23 Transgenic Mice
    Stalder, Martina, Phinney, Amie, Probst, Alphonse, Sommer, Bernd, Staufenbiel, Matthias, Jucker, Mathias · 1999 · The American Journal of Pathology
  35. Repetitive Mild Brain Trauma Accelerates Aβ Deposition, Lipid Peroxidation, and Cognitive Impairment in a Transgenic Mouse Model of Alzheimer Amyloidosis
    Uryu, Kunihiro, Laurer, Helmut, McIntosh, Tracy, Praticò, Domenico, Martinez, Daniel, Leight, Susan, Lee, Virginia M.-Y., Trojanowski, John Q. · 2002 · The Journal of Neuroscience
  36. Intraneuronal Aβ accumulation and origin of plaques in Alzheimer's disease
    Gouras, Gunnar K., Almeida, Claudia G., Takahashi, Reisuke H. · 2005 · Neurobiology of Aging
  37. Modulation of hippocampal cell proliferation, memory, and amyloid plaque deposition in APPsw (Tg2576) mutant mice by isolation stress
    Dong, H., Goico, B., Martin, M., Csernansky, C.A., Bertchume, A., Csernansky, J.G. · 2004 · Neuroscience
  38. 19F and 1H MRI detection of amyloid β plaques in vivo
    Higuchi, Makoto, Iwata, Nobuhisa, Matsuba, Yukio, Sato, Kumi, Sasamoto, Kazumi, Saido, Takaomi C · 2005 · Nature Neuroscience
  39. Transgenic mouse models of Alzheimer’s disease.
    Elder, Gregory A., Gama Sosa, Miguel A., De Gasperi, Rita · 2010 · Mount Sinai Journal of Medicine A Journal of Translational and Personalized Medicine
  40. Immune Signaling in Neurodegeneration
    Hammond, Timothy R., Marsh, Samuel E., Stevens, Beth · 2019 · Immunity
  41. Microglia and Alzheimer's disease pathogenesis
    Streit, Wolfgang J. · 2004 · Journal of Neuroscience Research
  42. Immunology and immunotherapy of Alzheimer's disease
    Weiner, Howard L., Frenkel, Dan · 2006 · Nature Reviews Immunology
  43. Melatonin increases survival and inhibits oxidative and amyloid pathology in a transgenic model of Alzheimer's disease
    Matsubara, Etsuro, Bryant‐Thomas, Tara, Pacheco Quinto, Javier, Henry, Tracey L., Poeggeler, Burkhard, Herbert, Donald, Cruz‐Sanchez, Felix, Chyan, Yau‐Jan, Smith, Mark A., Perry, George et al. · 2003 · Journal of Neurochemistry
  44. Nox2-derived radicals contribute to neurovascular and behavioral dysfunction in mice overexpressing the amyloid precursor protein
    Park, Laibaik, Zhou, Ping, Pitstick, Rose, Capone, Carmen, Anrather, Josef, Norris, Erin H., Younkin, Linda, Younkin, Steven, Carlson, George, McEwen, Bruce S. et al. · 2008 · Proceedings of the National Academy of Sciences
  45. Medicinal Inorganic Chemistry Approaches to Passivation and Removal of Aberrant Metal Ions in Disease
    Scott, Lauren E., Orvig, Chris · 2009 · Chemical Reviews
  46. Inflammaging as a prodrome to Alzheimer's disease
    Giunta, Brian, Fernandez, Francisco, Nikolic, William V, Obregon, Demian, Rrapo, Elona, Town, Terrence, Tan, Jun · 2008 · Journal of Neuroinflammation
  47. Copper-Dependent Inhibition of Human Cytochrome c Oxidase by a Dimeric Conformer of Amyloid-β1-42
    Crouch, Peter J., Blake, Rachel, Duce, James A., Ciccotosto, Giuseppe D., Li, Qiao-Xin, Barnham, Kevin J., Curtain, Cyril C., Cherny, Robert A., Cappai, Roberto, Dyrks, Thomas et al. · 2005 · The Journal of Neuroscience
  48. Transsynaptic progression of amyloid-β-induced neuronal dysfunction within the entorhinal-hippocampal network
    Harris, Julie A., Devidze, Nino, Verret, Laure, Ho, Kaitlyn, Halabisky, Brian, Thwin, Myo T., Kim, Daniel, Hamto, Patricia, Lo, Iris, Yu, Gui-Qiu et al. · 2010 · Neuron
  49. Tau Protein Is Required for Amyloid β-Induced Impairment of Hippocampal Long-Term Potentiation
    Shipton, Olivia A., Leitz, Julie R., Dworzak, Jenny, Acton, Christine E. J., Tunbridge, Elizabeth M., Denk, Franziska, Dawson, Hana N., Vitek, Michael P., Wade-Martins, Richard, Paulsen, Ole et al. · 2011 · The Journal of Neuroscience
  50. β-Amyloid Accumulation Impairs Multivesicular Body Sorting by Inhibiting the Ubiquitin-Proteasome System
    Almeida, Claudia G., Takahashi, Reisuke H., Gouras, Gunnar K. · 2006 · The Journal of Neuroscience
  51. Obesity‐related leptin regulates Alzheimer's Aβ
    Fewlass, Darius C., Noboa, Karina, Pi‐Sunyer, F. Xavier, Johnston, Jane M., Yan, Shi D., Tezapsidis, Nikolaos · 2004 · The FASEB Journal
  52. Inflammatory responses to amyloidosis in a transgenic mouse model of Alzheimer’s disease
    Matsuoka, Yasuji, Picciano, Melanie, Malester, Brian, LaFrancois, John, Zehr, Cindy, Daeschner, JoAnna M., Olschowka, John A., Fonseca, Maria I., O’Banion, M. Kerry, Tenner, Andrea J. et al. · 2001 · The American Journal of Pathology
  53. Amyloid triggers extensive cerebral angiogenesis causing blood brain barrier permeability and hypervascularity in Alzheimer's disease
    Biron, Kaan E., Dickstein, Dara L., Gopaul, Rayshad, Jefferies, Wilfred A. · 2011 · PLoS ONE
  54. Amyloid-β Deposits Lead to Retinal Degeneration in a Mouse Model of Alzheimer Disease
    Ning, Allison, Cui, Jing, To, Eleanor, Ashe, Karen Hsiao, Matsubara, Joanne · 2008 · Investigative Opthalmology & Visual Science
  55. Longitudinal, Quantitative Assessment of Amyloid, Neuroinflammation, and Anti-Amyloid Treatment in a Living Mouse Model of Alzheimer's Disease Enabled by Positron Emission Tomography
    Maeda, Jun, Ji, Bin, Irie, Toshiaki, Tomiyama, Takami, Maruyama, Masahiro, Okauchi, Takashi, Staufenbiel, Matthias, Iwata, Nobuhisa, Ono, Maiko, Saido, Takaomi C. et al. · 2007 · The Journal of Neuroscience
  56. Temporal memory deficits in Alzheimer’s mouse models: Rescue by genetic deletion of BACE1
    Ohno, Masuo, Chang, Lei, Tseng, Wilbur, Oakley, Holly, Citron, Martin, Klein, William L., Vassar, Robert, Disterhoft, John F. · 2006 · European Journal of Neuroscience
  57. Role of LRP1 in the pathogenesis of Alzheimer's disease: evidence from clinical and preclinical studies
    Shinohara, Mitsuru, Tachibana, Masaya, Kanekiyo, Takahisa, Bu, Guojun · 2017 · Journal of Lipid Research
  58. β-Secretase Activity Increases with Aging in Human, Monkey, and Mouse Brain
    Fukumoto, Hiroaki, Rosene, Douglas L., Moss, Mark B., Raju, Susan, Hyman, Bradley T., Irizarry, Michael C. · 2004 · The American Journal of Pathology
  59. Blood-brain barrier-associated pericytes internalize and clear aggregated amyloid-β42 by LRP1-dependent apolipoprotein E isoform-specific mechanism
    Ma, Qingyi, Zhao, Zhen, Sagare, Abhay P, Wu, Yingxi, Wang, Min, Owens, Nelly Chuqui, Verghese, Philip B, Herz, Joachim, Holtzman, David M, Zlokovic, Berislav V · 2018 · Molecular Neurodegeneration
  60. Cerebrovascular autoregulation is profoundly impaired in mice overexpressing amyloid precursor protein
    Niwa, Kiyoshi, Kazama, Ken, Younkin, Linda, Younkin, Steven G., Carlson, George A., Iadecola, Costantino · 2002 · American Journal of Physiology-Heart and Circulatory Physiology
  61. Olfactory Dysfunction Correlates with Amyloid-β Burden in an Alzheimer's Disease Mouse Model
    Wesson, Daniel W., Levy, Efrat, Nixon, Ralph A., Wilson, Donald A. · 2010 · The Journal of Neuroscience
  62. Activation of c-Jun N-Terminal Kinase and p38 in an Alzheimer's Disease Model Is Associated with Amyloid Deposition
    Savage, Mary J., Lin, Yin-Guo, Ciallella, John R., Flood, Dorothy G., Scott, Richard W. · 2002 · The Journal of Neuroscience
  63. Detection of a Novel Intraneuronal Pool of Insoluble Amyloid β Protein that Accumulates with Time in Culture
    Skovronsky, Daniel M., Doms, Robert W., Lee, Virginia M.-Y. · 1998 · The Journal of Cell Biology
  64. Mouse models of Alzheimer’s disease
    Esquerda-Canals, Gisela, Montoliu-Gaya, Laia, Güell-Bosch, Jofre, Villegas, Sandra · 2017 · Journal of Alzheimer’s Disease
  65. The role of microglia in processing and spreading of bioactive tau seeds in Alzheimer’s disease
    Hopp, Sarah C., Lin, Yang, Oakley, Derek, Roe, Allyson D., DeVos, Sarah L., Hanlon, David, Hyman, Bradley T. · 2018 · Journal of Neuroinflammation
  66. Time sequence of maturation of dystrophic neurites associated with Aβ deposits in APP/PS1 transgenic mice
    Blanchard, Véronique, Moussaoui, Saliha, Czech, Christian, Touchet, Nathalie, Bonici, Bruno, Planche, Michel, Canton, Thierry, Jedidi, Iness, Gohin, Micheline, Wirths, Oliver et al. · 2003 · Experimental Neurology
  67. A Comprehensive Behavioral Test Battery to Assess Learning and Memory in 129S6/Tg2576 Mice
    Wolf, Andrea, Bauer, Björn, Abner, Erin L., Ashkenazy-Frolinger, Tal, Hartz, Anika M. S. · 2016 · PLOS ONE
  68. Human Apolipoprotein E4 Alters the Amyloid-β 40:42 Ratio and Promotes the Formation of Cerebral Amyloid Angiopathy in an Amyloid Precursor Protein Transgenic Model
    Fryer, John D., Simmons, Kelly, Parsadanian, Maia, Bales, Kelly R., Paul, Steven M., Sullivan, Patrick M., Holtzman, David M. · 2005 · The Journal of Neuroscience
  69. Treatment with a C5aR Antagonist Decreases Pathology and Enhances Behavioral Performance in Murine Models of Alzheimer’s Disease
    Fonseca, Maria I, Ager, Rahasson R, Chu, Shu-Hui, Yazan, Ozkan, Sanderson, Sam D, LaFerla, Frank M, Taylor, Stephen M, Woodruff, Trent M, Tenner, Andrea J · 2009 · The Journal of Immunology
  70. Augmented Senile Plaque Load in Aged Female β-Amyloid Precursor Protein-Transgenic Mice
    Callahan, Michael J., Lipinski, William J., Bian, Feng, Durham, Robert A., Pack, Amy, Walker, Lary C. · 2001 · The American Journal of Pathology
  71. VPS35 haploinsufficiency increases Alzheimer’s disease neuropathology
    Wen, Lei, Tang, Fu-Lei, Hong, Yan, Luo, Shi-Wen, Wang, Chun-Lei, He, Wanxia, Shen, Chengyong, Jung, Ji-Ung, Xiong, Fei, Lee, Dae-hoon et al. · 2011 · Journal of Cell Biology
  72. Dysregulation of the mTOR pathway mediates impairment of synaptic plasticity in a mouse model of Alzheimer's disease
    Ma, Tao, Hoeffer, Charles A., Capetillo-Zarate, Estibaliz, Yu, Fangmin, Wong, Helen, Lin, Michael T., Tampellini, Davide, Klann, Eric, Blitzer, Robert D., Gouras, Gunnar K. · 2010 · PLoS ONE
  73. A Dynamic Relationship between Intracellular and Extracellular Pools of Aβ
    Oddo, Salvatore, Caccamo, Antonella, Smith, Ian F., Green, Kim N., LaFerla, Frank M. · 2006 · The American Journal of Pathology
  74. Intracellular Aβ and cognitive deficits precede β-amyloid deposition in transgenic arcAβ mice
    Knobloch, Marlen, Konietzko, Uwe, Krebs, Danielle C., Nitsch, Roger M. · 2007 · Neurobiology of Aging
  75. Brain Perivascular Macrophages Initiate the Neurovascular Dysfunction of Alzheimer Aβ Peptides
    Park, Laibaik, Uekawa, Ken, Garcia-Bonilla, Lidia, Koizumi, Kenzo, Murphy, Michelle, Pistik, Rose, Younkin, Linda, Younkin, Steven, Zhou, Ping, Carlson, George et al. · 2017 · Circulation Research
  76. Actin-binding Proteins Coronin-1a and IBA-1 are Effective Microglial Markers for Immunohistochemistry
    Ahmed, Zeshan, Shaw, Gerry, Sharma, Ved P., Yang, Cui, McGowan, Eileen, Dickson, Dennis W. · 2007 · Journal of Histochemistry & Cytochemistry
  77. Two-day radial-arm water maze learning and memory task; robust resolution of amyloid-related memory deficits in transgenic mice
    Alamed, Jennifer, Wilcock, Donna M, Diamond, David M, Gordon, Marcia N, Morgan, Dave · 2006 · Nature Protocols
  78. Amyloid-β Contributes to Blood–Brain Barrier Leakage in Transgenic Human Amyloid Precursor Protein Mice and in Humans With Cerebral Amyloid Angiopathy
    Hartz, Anika M.S., Bauer, Björn, Soldner, Emma L.B., Wolf, Andrea, Boy, Sandra, Backhaus, Roland, Mihaljevic, Ivan, Bogdahn, Ulrich, Klünemann, Hans H., Schuierer, Gerhard et al. · 2012 · Stroke
  79. NADPH Oxidase-Derived Reactive Oxygen Species Mediate the Cerebrovascular Dysfunction Induced by the Amyloid β Peptide
    Park, Laibaik, Anrather, Josef, Zhou, Ping, Frys, Kelly, Pitstick, Rose, Younkin, Steven, Carlson, George A., Iadecola, Costantino · 2005 · The Journal of Neuroscience
  80. Active and passive immunotherapy for neurodegenerative disorders
    Brody, David L., Holtzman, David M. · 2008 · Annual Review of Neuroscience
  81. Time Course of the Development of Alzheimer-like Pathology in the Doubly Transgenic PS1+APP Mouse
    Gordon, Marcia N., Holcomb, Leigh A., Jantzen, Paul T., DiCarlo, Giovanni, Wilcock, Donna, Boyett, Kristal W., Connor, Karen, Melachrino, Jason, O'Callaghan, James P., Morgan, Dave · 2002 · Experimental Neurology
  82. Selectively Reduced Expression of Synaptic Plasticity-Related Genes in Amyloid Precursor Protein + Presenilin-1 Transgenic Mice
    Dickey, Chad A., Loring, Jeanne F., Montgomery, Julia, Gordon, Marcia N., Eastman, P. Scott, Morgan, Dave · 2003 · The Journal of Neuroscience
  83. Dendrite and dendritic spine alterations in alzheimer models
    Moolman, Donna L., Vitolo, Ottavio V., Vonsattel, Jean-Paul G., Shelanski, Michael L. · 2004 · Journal of Neurocytology
  84. New Insights on How Metals Disrupt Amyloid β-Aggregation and Their Effects on Amyloid-β Cytotoxicity
    Yoshiike, Yuji, Tanemura, Kentaro, Murayama, Ohoshi, Akagi, Takumi, Murayama, Miyuki, Sato, Shinji, Sun, Xiaoyan, Tanaka, Nobuo, Takashima, Akihiko · 2001 · Journal of Biological Chemistry
  85. SOD1 (Copper/Zinc Superoxide Dismutase) Deficiency Drives Amyloid β Protein Oligomerization and Memory Loss in Mouse Model of Alzheimer Disease
    Murakami, Kazuma, Murata, Nakaba, Noda, Yoshihiro, Tahara, Shoichi, Kaneko, Takao, Kinoshita, Noriaki, Hatsuta, Hiroyuki, Murayama, Shigeo, Barnham, Kevin J., Irie, Kazuhiro et al. · 2011 · Journal of Biological Chemistry
  86. Genetics of β-Amyloid Precursor Protein in Alzheimer's Disease
    TCW, Julia, Goate, Alison M. · 2017 · Cold Spring Harbor Perspectives in Medicine
  87. Neurotoxic effects of thioflavin S-positive amyloid deposits in transgenic mice and Alzheimer’s disease
    Urbanc, B., Cruz, L., Le, R., Sanders, J., Ashe, K. Hsiao, Duff, K., Stanley, H. E., Irizarry, M. C., Hyman, B. T. · 2002 · Proceedings of the National Academy of Sciences
  88. Neurogenic Effect of -Amyloid Peptide in the Development of Neural Stem Cells
    Lopez-Toledano, M. A. · 2004 · Journal of Neuroscience
  89. Reversal of long-term dendritic spine alterations in Alzheimer disease models
    Smith, Donna L., Pozueta, Julio, Gong, Bing, Arancio, Ottavio, Shelanski, Michael · 2009 · Proceedings of the National Academy of Sciences
  90. Persistent Amyloidosis following Suppression of Aβ Production in a Transgenic Model of Alzheimer Disease
    Jankowsky, Joanna L, Slunt, Hilda H, Gonzales, Victoria, Savonenko, Alena V, Wen, Jason C, Jenkins, Nancy A, Copeland, Neal G, Younkin, Linda H, Lester, Henry A, Younkin, Steven G et al. · 2005 · PLoS Medicine
  91. Genetically engineered pigs as models for human disease
    Perleberg, Carolin, Kind, Alexander, Schnieke, Angelika · 2018 · Disease Models & Mechanisms
  92. Age-Related Amyloid β Deposition in Transgenic Mice Overexpressing Both Alzheimer Mutant Presenilin 1 and Amyloid β Precursor Protein Swedish Mutant Is Not Associated with Global Neuronal Loss
    Takeuchi, Ayano, Irizarry, Michael C., Duff, Karen, Saido, Takaomi C., Hsiao Ashe, Karen, Hasegawa, Masato, Mann, David M.A., Hyman, Bradley T., Iwatsubo, Takeshi · 2000 · The American Journal of Pathology
  93. Amyloid-β Peptides Interact with Plasma Proteins and Erythrocytes: Implications for Their Quantitation in Plasma
    Kuo, Yu-Min, Kokjohn, Tyler A., Kalback, Walter, Luehrs, Dean, Galasko, Douglas R., Chevallier, Nathalie, Koo, Edward H., Emmerling, Mark R., Roher, Alex E. · 2000 · Biochemical and Biophysical Research Communications
  94. Immunotherapy for Alzheimer’s disease: Key Symposium: Immunotherapy for Alzheimer’s disease
    Morgan, D. · 2011 · Journal of Internal Medicine
  95. Dendritic spine loss in the hippocampus of young PDAPP and Tg2576 mice and its prevention by the ApoE2 genotype
    Lanz, T.A, Carter, D.B, Merchant, K.M · 2003 · Neurobiology of Disease
  96. The amyloid hypothesis, time to move on: Amyloid is the downstream result, not cause, of Alzheimer's disease
    Drachman, David A. · 2014 · Alzheimer's & Dementia
  97. Intrahippocampal LPS injections reduce Aβ load in APP+PS1 transgenic mice
    DiCarlo, G · 2001 · Neurobiology of Aging
  98. Alterations in cerebral blood flow and glucose utilization in mice overexpressing the amyloid precursor protein
    Niwa, Kiyoshi, Kazama, Ken, Younkin, Steven G., Carlson, George A., Iadecola, Costantino · 2002 · Neurobiology of Disease
  99. β-Amyloid Peptide at Sublethal Concentrations Downregulates Brain-Derived Neurotrophic Factor Functions in Cultured Cortical Neurons
    Tong, Liqi, Balazs, Robert, Thornton, Phillip L., Cotman, Carl W. · 2004 · The Journal of Neuroscience
  100. TREM2 and the neuroimmunology of Alzheimer's disease
    Hickman, Suzanne E., El Khoury, Joseph · 2014 · Biochemical Pharmacology