Engineered CRISPR-Cas9 nuclease with expanded targeting space

Coot : model-building tools for molecular graphics

Emsley, P., & Cowtan, K. (2004) · Acta Crystallographica Section D Biological Crystallography · doi:10.1107/s0907444904019158 · Cited by 30,571

PHENIX : a comprehensive Python-based system for macromolecular structure solution

Adams, P. D., Afonine, P. V., Bunkóczi, G., Chen, V. B., Davis, I. W., Echols, N., Headd, J. J., Hung, L.-W., Kapral, G. J., Grosse-Kunstleve, R. W., et al. (2010) · Acta Crystallographica Section D Biological Crystallography · doi:10.1107/s0907444909052925 · Cited by 23,716

A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity

Jinek, M., Chylinski, K., Fonfara, I., Hauer, M., Doudna, J. A., & Charpentier, E. (2012) · Science · doi:10.1126/science.1225829 · Cited by 17,116

XDS

Kabsch, W. (2010) · Acta Crystallographica Section D Biological Crystallography · doi:10.1107/s0907444909047337 · Cited by 16,463

Multiplex Genome Engineering Using CRISPR/Cas Systems

Cong, L., Ran, F. A., Cox, D., Lin, S., Barretto, R., Habib, N., Hsu, P. D., Wu, X., Jiang, W., Marraffini, L. A., et al. (2013) · Science · doi:10.1126/science.1231143 · Cited by 15,339

Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage

Komor, A. C., Kim, Y. B., Packer, M. S., Zuris, J. A., & Liu, D. R. (2016) · Nature · doi:10.1038/nature17946 · Cited by 5,437

Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System

Zetsche, B., Gootenberg, J. S., Abudayyeh, O. O., Slaymaker, I. M., Makarova, K. S., Essletzbichler, P., Volz, S. E., Joung, J., van der Oost, J., Regev, A., et al. (2015) · Cell · doi:10.1016/j.cell.2015.09.038 · Cited by 4,761

DNA targeting specificity of RNA-guided Cas9 nucleases

Hsu, P. D., Scott, D. A., Weinstein, J. A., Ran, F. A., Konermann, S., Agarwala, V., Li, Y., Fine, E. J., Wu, X., Shalem, O., et al. (2013) · Nature Biotechnology · doi:10.1038/nbt.2647 · Cited by 4,741

How good are my data and what is the resolution?

Evans, P. R., & Murshudov, G. N. (2013) · Acta Crystallographica Section D Biological Crystallography · doi:10.1107/s0907444913000061 · Cited by 4,713

Molecular replacement with MOLREP

Vagin, A. A., & Teplyakov, A. (2009) · Acta Crystallographica Section D Biological Crystallography · doi:10.1107/s0907444909042589 · Cited by 3,580

Site-specific genome editing in treatment of inherited diseases: possibility, progress, and perspectives

Huang, C., Li, Q., & Li, J. (2022) · Medical Review · doi:10.1515/mr-2022-0029 · Cited by 20

Precise Correction of Lhcgr Mutation in Stem Leydig Cells by Prime Editing Rescues Hereditary Primary Hypogonadism in Mice

Xia, K., Wang, F., Tan, Z., Zhang, S., Lai, X., Ou, W., Yang, C., Chen, H., Peng, H. Y., Luo, P., et al. (2023) · Advanced Science · doi:10.1002/advs.202300993 · Cited by 20

Unbiased interrogation of functional lysine residues in human proteome

Bao, Y., Pan, Q., Xu, P., Liu, Z., Zhang, Z., Liu, Y., Xu, Y., Yu, Y., Zhou, Z. L., & Wei, W. (2023) · Molecular Cell · doi:10.1016/j.molcel.2023.10.033 · Cited by 19

Target DNA-dependent activation mechanism of the prokaryotic immune system SPARTA

Finocchio, G., Koopal, B., Potocnik, A., Heijstek, C., Westphal, A. H., Jínek, M., & Swarts, D. C. (2023) · Nucleic Acids Research · doi:10.1093/nar/gkad1248 · Cited by 20

Health research in the era of artificial intelligence: Advances in gene-editing study

Dai, M., Li, X., Zhang, Q., Liang, T., Huang, X., & Fu, Q. (2024) · Medicine Plus · doi:10.1016/j.medp.2024.100027 · Cited by 19

Blossom of CRISPR technologies and applications in disease treatment

Liu, H., Wang, L., & Luo, Y. (2018) · Synthetic and Systems Biotechnology · doi:10.1016/j.synbio.2018.10.003 · Cited by 19

Modeling Niemann–Pick disease type C in a human haploid cell line allows for patient variant characterization and clinical interpretationPreprint

Erwood, S., Brewer, R. A., Bily, T. M. I., Maino, E., Zhou, L., Cohn, R. D., & Ivakine, E. A. (2019) · Genome Research · doi:10.1101/gr.250720.119 · Cited by 20

Base Editing in Human Cells to Produce Single‐Nucleotide‐Variant Clonal Cell Lines

Vásquez, C. A., Cowan, Q. T., & Komor, A. C. (2020) · Current Protocols in Molecular Biology · doi:10.1002/cpmb.129 · Cited by 20

Identification of SaCas9 orthologs containing a conserved serine residue that determines simple NNGG PAM recognition

Wang, S., Tao, C., Mao, H., Hou, L., Wang, Y., Qi, T., Yang, Y., Ong, S., Hu, S., Chai, R., et al. (2022) · PLoS Biology · doi:10.1371/journal.pbio.3001897 · Cited by 18

Precise genome editing with base editors

Liu, H., Zhu, Y., Li, M., & Gu, Z. (2023) · Medical Review · doi:10.1515/mr-2022-0044 · Cited by 19

Recent Advances in CRISPR/Cas9-Mediated Genome Editing in Dictyostelium

Muramoto, T., Iriki, H., Watanabe, J., & Kawata, T. (2019) · Cells · doi:10.3390/cells8010046 · Cited by 19

Prediction of synonymous corrections by the BE-FF computational tool expands the targeting scope of base editing

Rabinowitz, R., Abadi, S., Almog, S., & Offen, D. (2020) · Nucleic Acids Research · doi:10.1093/nar/gkaa215 · Cited by 18

CRISPR-Guided Programmable Self-Assembly of Artificial Virus-Like Nucleocapsids

Calcines-Cruz, C., Finkelstein, I. J., & Hernández-García, A. (2021) · Nano Letters · doi:10.1021/acs.nanolett.0c04640 · Cited by 18

Advances in Accurate Microbial Genome-Editing CRISPR Technologies

Lee, H. J., & Lee, S. J. (2021) · Journal of Microbiology and Biotechnology · doi:10.4014/jmb.2106.06056 · Cited by 19

Base and Prime Editing in the Retina—From Preclinical Research toward Human Clinical Trials

Yee, T., & Wert, K. J. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232012375 · Cited by 21

Protocol to create isogenic disease models from adult stem cell-derived organoids using next-generation CRISPR tools

Celotti, M., Derks, L. L. M., van Es, J., van Boxtel, R., Clevers, H., & Geurts, M. H. (2024) · STAR Protocols · doi:10.1016/j.xpro.2024.103189 · Cited by 17

A streamlined base editor engineering strategy to reduce bystander editing

Valdez, I., O’Connor, I., Patel, D., Gierer, K., Harrington, J., Ellis, E., Caponetti, S. A., Sebra, R., Valley, H. C., Coote, K. J., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-63609-6 · Cited by 17

Advances and Applications of Plant Base Editing Technologies

Peng, H. F., Li, J., Sun, K., Tang, H., Huang, W., Li, X., Wang, S., Ding, K., Han, Z., Li, Z., et al. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26199452 · Cited by 20

High-Fidelity Cytosine Base Editing in a GC-Rich Corynebacterium glutamicum with Reduced DNA Off-Target Editing Effects

Heo, Y. B., Hwang, G., Kang, S. W., Bae, S., & Woo, H. M. (2022) · Microbiology Spectrum · doi:10.1128/spectrum.03760-22 · Cited by 17

Genome editing for vegetatively propagated crops improvement: a new horizon of possibilities

Lakhani, H., Thakur, N., & Tiwari, S. (2022) · Journal of Plant Biochemistry and Biotechnology · doi:10.1007/s13562-022-00819-9 · Cited by 17

The Wild‐Type tRNA Adenosine Deaminase Enzyme TadA Is Capable of Sequence‐Specific DNA Base Editing

Ranzau, B. L., Rallapalli, K. L., Evanoff, M., Paesani, F., & Komor, A. C. (2023) · ChemBioChem · doi:10.1002/cbic.202200788 · Cited by 17

CRISPR/Cas in Grapevine Genome Editing: The Best Is Yet to Come

Ren, C., Mohamed, M. S. M., Aini, N., Kuang, Y., & Liang, Z. (2024) · Horticulturae · doi:10.3390/horticulturae10090965 · Cited by 18

Multiplex base editing to protect from CD33 directed drugs for immune and gene therapy

Borot, F., Humbert, O., Ehmsen, J. T., Fields, E., Kohli, S., Radtke, S., Swing, K., Pande, D., Enstrom, M., Laszlo, G. S., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-59713-2 · Cited by 17

Versatile transcription control based on reversible dCas9 binding

Widom, J. R., Rai, V., Rohlman, C. E., & Walter, N. G. (2019) · RNA · doi:10.1261/rna.071613.119 · Cited by 18

Advances in CRISPR/Cas9-mediated genome editing on vegetable crops

Tian, S., Xing, S., & Xu, Y. (2021) · In Vitro Cellular & Developmental Biology - Plant · doi:10.1007/s11627-021-10187-z · Cited by 17

Perfecting Targeting in CRISPR

Zhang, H., Li, T., Sun, Y., & Yang, H. (2021) · Annual Review of Genetics · doi:10.1146/annurev-genet-071719-030438 · Cited by 18

CRISPR/Cas correction of muscular dystrophies

Zhang, Y., Nishiyama, T., Olson, E. N., & Bassel‐Duby, R. (2021) · Experimental Cell Research · doi:10.1016/j.yexcr.2021.112844 · Cited by 18

Base editing the mammalian genome

Schatoff, E. M., Zafra, M. P., & Dow, L. E. (2019) · Methods · doi:10.1016/j.ymeth.2019.02.022 · Cited by 20

Base editing in Streptomyces with Cas9-deaminase fusionsPreprint

Zhong, Z., Guo, J., Deng, L., Chen, L., Wang, J., Li, S., Xu, W. Q., Deng, Z., & Sun, Y. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/630137 · Cited by 17

Development of a highly efficient base editing system for Lactobacilli to improve probiotics and dissect essential functions

Mitsunobu, H., Kita, Y., Nambu-Nishida, Y., Miyazaki, S., Nakajima, K., Taoka, K.-I., Kondo, A., & Nishida, K. (2025) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-025-13489-z · Cited by 16

Engineering eukaryotic transposon-encoded Fanzor2 system for genome editing in mammals

Wei, Y., Gao, P., Pan, D., Li, G., Chen, Y., Li, S., Jiang, H., Yang, Y., Liu, Z., Liu, Z., et al. (2025) · Nature Chemical Biology · doi:10.1038/s41589-025-01902-7 · Cited by 16

Correcting inborn errors of immunity: From viral mediated gene addition to gene editing

Castiello, M. C., Ferrari, S., & VILLA, A. M. (2023) · Seminars in Immunology · doi:10.1016/j.smim.2023.101731 · Cited by 16

Protospacer modification improves base editing of a canonical splice site variant and recovery of CFTR function in human airway epithelial cells

Joynt, A. T., Kavanagh, E. W., Newby, G. A., Mitchell, S., Eastman, A. C., Paul, K. C., Bowling, A. D., Osorio, D. L., Merlo, C. A., Patel, S. U., et al. (2023) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2023.06.020 · Cited by 16

Blood vessel organoids generated by base editing and harboring single nucleotide variation in Notch3 effectively recapitulate CADASIL-related pathogenesis

Ahn, Y., An, J.-H., Yang, H.-J., Lee, W.-J., Lee, S., Park, Y., Lee, J. H., Lee, H. J., Lee, S. H., & Kim, S. (2024) · Molecular Neurobiology · doi:10.1007/s12035-024-04141-4 · Cited by 16

Genome editing: An insight into disease resistance, production efficiency, and biomedical applications in livestock

Yuan, Y., Liu, S.-Z., Farhab, M., Lv, M.-Y., Zhang, T., & Cao, S.-X. (2024) · Functional & Integrative Genomics · doi:10.1007/s10142-024-01364-5 · Cited by 18

Precision in Action: The Role of Clustered Regularly Interspaced Short Palindromic Repeats/Cas in Gene Therapies

Banda, A., Impomeni, O., Singh, A., Baloch, A. R., Hu, W., & Jaijyan, D. K. (2024) · Vaccines · doi:10.3390/vaccines12060636 · Cited by 16

DNA targeting by compact Cas9d and its resurrected ancestor

Ocampo, R. F., Bravo, J. P. K., Dangerfield, T. L., Nocedal, I., Jirde, S. A., Alexander, L. M., Thomas, N. C., Das, A., Nielson, S., Johnson, K. A., et al. (2025) · Nature Communications · doi:10.1038/s41467-024-55573-4 · Cited by 17

The potential application of genome editing by using CRISPR/Cas9, and its engineered and ortholog variants for studying the transcription factors involved in the maintenance of phosphate homeostasis in model plants

Jyoti, A., Kaushik, S., Srivastava, V. K., Datta, M., Kumar, S., Yugandhar, P., Kothari, S. L., Rai, V., & Jain, A. (2019) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2019.03.010 · Cited by 17

‘Artificial spermatid’-mediated genome editing†

Wang, L., & Li, J. (2019) · Biology of Reproduction · doi:10.1093/biolre/ioz087 · Cited by 16

Methods of Modification of Mesenchymal Stem Cells and Conditions of Their Culturing for Hyaline Cartilage Tissue Engineering

Shestovskaya, M. V., Божкова, С. А., Sopova, J. V., Георгиевич, Х. М., & Bozhokin, M. S. (2021) · Biomedicines · doi:10.3390/biomedicines9111666 · Cited by 16

Multiple isogenic GNE-myopathy modeling with mutation specific phenotypes from human pluripotent stem cells by base editors

Park, J.-C., Kim, J., Jang, H., Lee, S., Kim, K.-T., Kwon, E., Park, S., Lee, H. S., Choi, H., Park, S., et al. (2022) · Biomaterials · doi:10.1016/j.biomaterials.2022.121419 · Cited by 16

CRISPR-Cas Mediated Genome Editing: A Paradigm Shift towards Sustainable Agriculture and Biotechnology

Rehman, R. S., Zafar, S. A., Ali, M., Pasha, A. N., Naveed, M. S., Waseem, M., Ahmad, M., & Raza, A. (2022) · Asian Plant Research Journal · doi:10.9734/aprj/2022/v9i130197 · Cited by 16

A CRISPR-guided mutagenic DNA polymerase strategy for the detection of antibiotic-resistant mutations in M. tuberculosis

Feng, S., Liang, L., Shen, C., Lin, D., Li, J., Lyu, L., Liang, W., Zhong, L., Cook, G. M., Doi, Y., et al. (2022) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2022.07.004 · Cited by 16

Integration of a FT expression cassette into CRISPR/Cas9 construct enables fast generation and easy identification of transgene-free mutants in Arabidopsis

Cheng, Y., Zhang, N., Hussain, S., Ahmed, S., Yang, W., & Wang, S. (2019) · PLoS ONE · doi:10.1371/journal.pone.0218583 · Cited by 17

Correction of the pathogenic mutation in TGM1 gene by adenine base editing in mutant embryos

Dang, L., Zhou, X., Zhong, X., Yu, W., Huang, S., Liu, H., Chen, Y., Zhang, W., Yuan, L., Li, L., et al. (2021) · Molecular Therapy · doi:10.1016/j.ymthe.2021.05.007 · Cited by 16

Computational design of novel Cas9 PAM-interacting domains using evolution-based modelling and structural quality assessment

Malbranke, C., Rostain, W., Depardieu, F., Cocco, S., Monasson, R., & Bikard, D. (2023) · PLOS Computational Biology · doi:10.1371/journal.pcbi.1011621 · Cited by 15

Emerging trends in gene and cell therapy: CRISPR in DNA editing and beyond

Ji, R., Chen, Q., & Zhang, Y. (2025) · Cell Reports Medicine · doi:10.1016/j.xcrm.2025.102459 · Cited by 14

Generation of genetically modified mice using SpCas9-NG engineered nuclease

Fujii, W., Ito, H., Kanke, T., Ikeda, A., Sugiura, K., & Naito, K. (2019) · Scientific Reports · doi:10.1038/s41598-019-49394-5 · Cited by 16

In vivo application of base and prime editing to treat inherited retinal diseases

Jo, D. H., Bae, S., Kim, S., Kim, J., & Kim, J. H. (2022) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2022.101132 · Cited by 15

Protocol for gene characterization in Aspergillus niger using 5S rRNA-CRISPR-Cas9-mediated Tet-on inducible promoter exchange

Zheng, X., Cairns, T. C., Zheng, P., Meyer, V., & Sun, J. (2022) · STAR Protocols · doi:10.1016/j.xpro.2022.101838 · Cited by 15

Decoding CRISPR–Cas PAM recognition with UniDesign

Huang, X., Zhou, J., Yang, D., Zhang, J., Xia, X., Chen, Y. E., & Xu, J. (2023) · Briefings in Bioinformatics · doi:10.1093/bib/bbad133 · Cited by 16

Targeting Duchenne muscular dystrophy by skipping DMD exon 45 with base editors

Gapinske, M., Winter, J., Swami, D., Gapinske, L., Woods, W. S., Shirguppe, S., Miskalis, A., Busza, A. M., Joulani, D., Kao, C. J., et al. (2023) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2023.07.029 · Cited by 16

DNA-GPS: A theoretical framework for optics-free spatial genomics and synthesis of current methods

Greenstreet, L., Afanassiev, A., Kijima, Y., Heitz, M., Ishiguro, S., King, S. B., Yachie, N., & Schiebinger, G. R. (2023) · Cell Systems · doi:10.1016/j.cels.2023.08.005 · Cited by 15

Genome and transcriptome engineering by compact and versatile CRISPR-Cas systems

Aquino‐Jarquín, G. (2023) · Drug Discovery Today · doi:10.1016/j.drudis.2023.103793 · Cited by 15

A Rapid Antibody Enhancement Platform in Saccharomyces cerevisiae Using an Improved, Diversifying CRISPR Base Editor

Cazier, A. P., Irvin, O. M., Chávez, L. S., Dalvi, S., Abraham, H., Wickramanayake, N., Yellayi, S., & Blazeck, J. (2023) · ACS Synthetic Biology · doi:10.1021/acssynbio.3c00299 · Cited by 15

Precise base editing without unintended indels in human cells and mouse primary myoblasts

Yoon, D. E., Kim, N., Park, S.-J., Jeong, T. Y., Eun, B., Cho, Y., Lim, S., Lee, H., Seong, J. K., & Kim, K. (2023) · Experimental & Molecular Medicine · doi:10.1038/s12276-023-01128-4 · Cited by 15

The immune system of prokaryotes: potential applications and implications for gene editing

Liu, S. M., Liu, H., Wang, X., & Shi, L. (2024) · Biotechnology Journal · doi:10.1002/biot.202300352 · Cited by 16

Genome editing in grass plants

Char, S. N., & Yang, B. (2019) · aBIOTECH · doi:10.1007/s42994-019-00005-x · Cited by 15

Development of Whole Genome‐Scale Base Editing Toolbox to Promote Efficiency of Extracellular Electron Transfer in Shewanella oneidensis MR‐1

Chen, Y., Fang, L., Ying, X., Cheng, M., Wang, L., Sun, P., Zhang, Z., Shi, L., Cao, Y., & Song, H. (2022) · Advanced Biology · doi:10.1002/adbi.202101296 · Cited by 15

Exploring and engineering PAM-diverse Streptococci Cas9 for PAM-directed bifunctional and titratable gene control in bacteria

Wang, J., Teng, Y., Gong, X., Zhang, J., Wu, Y., Lou, L., Li, M., Xie, Z., & Yan, Y. (2022) · Metabolic Engineering · doi:10.1016/j.ymben.2022.10.005 · Cited by 16

Genome editing with natural and engineered CjCas9 orthologs

Gao, S., Wang, Y., Qi, T., Wei, J., Hu, Z., Liu, J., Sun, S., Liu, H., & Wang, Y. (2023) · Molecular Therapy · doi:10.1016/j.ymthe.2023.01.029 · Cited by 16

Engineering CRISPR-Cas9 RNA–Protein Complexes for Improved Function and Delivery

Rouet, R., de Oñate, L., Li, J., Murthy, N., & Wilson, R. C. (2018) · The CRISPR Journal · doi:10.1089/crispr.2018.0037 · Cited by 16

Improving Editing Efficiency for the Sequences with NGH PAM Using xCas9-Derived Base Editors

Liu, X., Li, G., Zhou, X., Qiao, Y., Wang, R., Tang, S., Liu, J., Wang, L., & Huang, X. (2019) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2019.06.024 · Cited by 15

AI-driven advances in plant biotechnology: sharpening the edge of plant tissue culture and genome editing

Narra, M., Ray, A., Polley, B., Yang, H., & Bhowmik, P. (2025) · Frontiers in Plant Science · doi:10.3389/fpls.2025.1718810 · Cited by 16

Efficient base editing in tomato using a highly expressed transient system

Yuan, S., Kawasaki, S., Abdellatif, I. M. Y., Nishida, K., Kondo, A., Ariizumi, T., Ezura, H., & Miura, K. (2021) · Plant Cell Reports · doi:10.1007/s00299-021-02662-z · Cited by 14

Design and application of the transformer base editor in mammalian cells and mice

Han, W., Gao, B., Zhu, J., He, Z., Li, J., Yang, L. C., & Chen, J. (2023) · Nature Protocols · doi:10.1038/s41596-023-00877-w · Cited by 15

Analyzing the functional effects of DNA variants with gene editing

Cooper, S., Obolenski, S., Waters, A. J., Bassett, A. R., & Coelho, M. A. (2024) · Cell Reports Methods · doi:10.1016/j.crmeth.2024.100776 · Cited by 14

Current Knowledge of Base Editing and Prime Editing

Averina, O. A., Kuznetsova, S. A., Permyakov, O. A., & Владимирович, С. П. (2024) · Molecular Biology · doi:10.1134/s0026893324700195 · Cited by 14

Amelioration of metabolic and behavioral defects through base editing in the PahR408W phenylketonuria mouse model

Yin, S., Gao, L., Sun, X., Zhang, M., Gao, H.-Y., Chen, X., Zhang, D., Ming, X., Yang, L., Hu, Y., et al. (2024) · Molecular Therapy · doi:10.1016/j.ymthe.2024.11.032 · Cited by 14

CRISPR-Cas Systems: A Functional Perspective and Innovations

Navarro, C., Diaz, M. P., Durán, P., Castro, A., Díaz, A., Cano, C., Carbonell, A., Solano-Jimenez, D.-S., Rivera-Porras, D., Contreras-Velásquez, J., et al. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26083645 · Cited by 16

CRISPR-based functional genomics tools in vertebrate models

Varshney, G. K., & Burgess, S. M. (2025) · Experimental & Molecular Medicine · doi:10.1038/s12276-025-01514-0 · Cited by 18

The Acidaminococcus sp. Cas12a nuclease recognizes GTTV and GCTV as non-canonical PAMs

Jacobsen, T. L., Liao, C., & Beisel, C. L. (2019) · FEMS Microbiology Letters · doi:10.1093/femsle/fnz085 · Cited by 15

Genome Editing Technology and Its Application to Metabolic Engineering in Rice

Sukegawa, S., Toki, S., & Saika, H. (2022) · Rice · doi:10.1186/s12284-022-00566-4 · Cited by 15

Comprehending the evolution of gene editing platforms for crop trait improvement

Dhakate, P., Sehgal, D., Vaishnavi, S., Chandra, A., Singh, A., Raina, S. N., & Rajpal, V. R. (2022) · Frontiers in Genetics · doi:10.3389/fgene.2022.876987 · Cited by 14

The Power of Gene Technologies: 1001 Ways to Create a Cell Model

Karagyaur, M. N., Primak, A. L., Efimenko, A. Y., Никитична, С. М., & Va, T. (2022) · Cells · doi:10.3390/cells11203235 · Cited by 14

Evaluation of genome and base editing tools in maize protoplasts

Fierlej, Y., Jacquier, N. M. A., Guille, L., Just, J., Montes, É., Richard, C., Loue-Manifel, J., Depège‐Fargeix, N., Gaillard, A., Widiez, T., et al. (2022) · Frontiers in Plant Science · doi:10.3389/fpls.2022.1010030 · Cited by 15

Enhancing the quality of staple food crops through CRISPR/Cas-mediated site-directed mutagenesis

Adeyinka, O. S., Tabassum, B., Landry, K. B., & Ogungbe, I. V. (2023) · Planta · doi:10.1007/s00425-023-04110-6 · Cited by 16

Enhancing prime editor flexibility with coiled-coil heterodimers

Mu, S., Chen, H., Li, Q., Gou, S., Liu, X., Wang, J., Zheng, W., Chen, M., Jin, Q., Lai, L., et al. (2024) · Genome biology · doi:10.1186/s13059-024-03257-z · Cited by 14

Current trends in gene therapy to treat inherited disorders of the brain

Matuszek, Ż., Brown, B. L., Yrigollen, C. M., Keiser, M. S., & Davidson, B. L. (2025) · Molecular Therapy · doi:10.1016/j.ymthe.2025.03.057 · Cited by 13

Why Does the E1219V Mutation Expand T-Rich PAM Recognition in Cas9 from Streptococcus pyogenes?

Bhattacharya, S., & Satpati, P. (2024) · Journal of Chemical Information and Modeling · doi:10.1021/acs.jcim.3c01515 · Cited by 13

Gene editing therapy for cardiovascular diseases

Wu, X., Yang, J., Zhang, J., & Song, Y. (2024) · MedComm · doi:10.1002/mco2.639 · Cited by 14

Advancements of CRISPR-Mediated Base Editing in Crops and Potential Applications in Populus

Yang, X., Zhu, P., & Gui, J. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25158314 · Cited by 13

Amphiphilic shuttle peptide delivers base editor ribonucleoprotein to correct the CFTR R553X mutation in well-differentiated airway epithelial cells

Kulhánková, K., Cheng, A. X., Traore, S., Auger, M., Pelletier, M., Hervault, M., Wells, K. D., Green, J. A., Byrne, A. K., Nelson, B., et al. (2024) · Nucleic Acids Research · doi:10.1093/nar/gkae819 · Cited by 14

Comparison of CRISPR/Cas9 and Cas12a for gene editing in Chlamydomonas reinhardtii

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