Cited by 364

The DOI matches its Crossref record; 248 of the 248 references it cites were found in a registry or an index.

Nutrition and Aging: Changes in the Regulation of Energy Metabolism With Aging

Roberts, Susan B., Rosenberg, Irwin·2006·Physiological Reviews

DOI 10.1152/physrev.00019.2005

Open this paper in CoChat — free account

Abstract

Changes in energy regulation occur during normal aging and contribute to the common phenomenon of weight and fat losses late in life. This review synthesizes data on aging-related changes in energy intake and energy expenditure and on the regulation of energy intake and expenditure. The ability of older adults to accurately regulate energy intake is impaired, with a number of possible explanations including delayed rate of absorption of macronutrients secondary to reductions in taste and smell acuity and numerous hormonal and metabolic mediators of energy regulation that change with aging. There are also changes in patterns of dietary intake and a reduction in the variety of foods consumed in old age that are thought to further reduce energy intake. Additionally, all components of energy expenditure decrease with aging, in particular energy expenditure for physical activity and basal metabolic rate, and the ability of energy expenditure to increase or decrease to attenuate energy imbalance during overeating or undereating also decreases. Combined, these changes result in an increased susceptibility to energy imbalance (both positive and negative) in old age that is associated with deteriorations in health. Practical interventions for prevention of weight and fat fluctuations in old age are anticipated here based on emerging knowledge of the role of such factors as dietary variety, taste, and palatability in late-life energy regulation.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1152/physrev.00019.2005

Cites

248 of 248 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Positional cloning of the mouse obese gene and its human homologue
Zhang, Y., Proenca, R., Maffei, M., Barone, M., Leopold, L., & Friedman, J. M. (1994) · Nature · doi:10.1038/372425a0 · Cited by 13,419
Central nervous system control of food intake
Schwartz, M. W., Woods, S. C., Porte, D., Seeley, R. J., & Baskin, D. G. (2000) · Nature · doi:10.1038/35007534 · Cited by 6,451
Serum Immunoreactive-Leptin Concentrations in Normal-Weight and Obese Humans
Considine, R. V., Sinha, M. K., Heiman, M. L., Kriauciunas, A., Stephens, T. W., Nyce, M. R., Ohannesian, J. P., Marco, C. C., McKee, L. J., Bauer, T. L., et al. (1996) · New England Journal of Medicine · doi:10.1056/nejm199602013340503 · Cited by 6,326
The three-factor eating questionnaire to measure dietary restraint, disinhibition and hunger
Stunkard, A. J., & Messick, S. (1985) · Journal of Psychosomatic Research · doi:10.1016/0022-3999(85)90010-8 · Cited by 4,687
Weight-Reducing Effects of the Plasma Protein Encoded by the obese Gene
Halaas, J. L., Gajiwala, K. S., Maffei, M., Cohen, S. L., Chait, B. T., Rabinowitz, D., Lallone, R. L., Burley, S. K., & Friedman, J. M. (1995) · Science · doi:10.1126/science.7624777 · Cited by 4,451
Recombinant Mouse OB Protein: Evidence for a Peripheral Signal Linking Adiposity and Central Neural Networks
Campfield, L. A., Smith, F. J., Guisez, Y., Devos, R., & Burn, P. (1995) · Science · doi:10.1126/science.7624778 · Cited by 3,243
Overweight and obesity in the United States: prevalence and trends, 1960–1994
Flegal, K., Carroll, M., Kuczmarski, R., & Johnson, C. (1998) · International Journal of Obesity · doi:10.1038/sj.ijo.0800541 · Cited by 3,045
Energy and protein requirements*
(2019) · Agricultural Development and Nutrition · doi:10.4324/9780429036279-4 · Cited by 2,545
Energy and protein requirements : report of a Joint FAO/WHO/UNU Expert Consultation
Fao, J., Energy, U. E. C. O., & Requirements, P. (1985) · Medical Entomology and Zoology · Cited by 1,857
Cholecystokinin decreases food intake in rats.
Gibbs, J., Young, R. C., & Smith, G. P. (1973) · Journal of Comparative and Physiological Psychology · doi:10.1037/h0034870 · Cited by 1,491
Smell Identification Ability: Changes with Age
Doty, R. L., Shaman, P., Applebaum, S. L., Giberson, R., Siksorski, L., & Rosenberg, L. (1984) · Science · doi:10.1126/science.6505700 · Cited by 1,325
The Response to Long-Term Overfeeding in Identical Twins
Bouchard, C., Tremblay, A., Després, J.-P., Nadeau, A., Lupien, P. J., Thériault, G., Dussault, J., Moorjani, S., Pinault, S., & Fournier, G. (1990) · New England Journal of Medicine · doi:10.1056/nejm199005243222101 · Cited by 1,278
Handbook of the Biology of Aging
Finch, C. E., & Schneider, E. L. (1990) · DigitalGeorgetown (Georgetown University Library) · Cited by 1,210
The Anthropology of Food and Eating
Mintz, S. W., & Du Bois, C. M. (2002) · Annual Review of Anthropology · doi:10.1146/annurev.anthro.32.032702.131011 · Cited by 1,174
Signals That Regulate Food Intake and Energy Homeostasis
Woods, S. C., Seeley, R. J., Porte, D., & Schwartz, M. W. (1998) · Science · doi:10.1126/science.280.5368.1378 · Cited by 1,169
Present Knowledge in Nutrition.
(1954) · Journal of the American Medical Association · doi:10.1001/jama.1954.03690350086043 · Cited by 1,044
Department of Health and Human Services
(2002) · Handbook of Research Design & Social Measurement · doi:10.4135/9781412984386.n104 · Cited by 1,032
Theory of use of the turnover rates of body water for measuring energy and material balance
Lifson, N., & McClintock, R. (1966) · Journal of Theoretical Biology · doi:10.1016/0022-5193(66)90185-8 · Cited by 981
Hunger: Basic mechanisms and clinical implications
(1976) · Neuroscience · doi:10.1016/0306-4522(76)90139-1 · Cited by 917
Regulation of energy intake and the body weight: the glucostatic theory and the lipostatic hypothesis.
Mayer, J. (1955) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1955.tb36543.x · Cited by 858
Dietary supplementation in elderly patients with fractured neck of the femur
Delmi, M., Rapin, C.-H., Bengoa, J.-M., Bonjour, J.-P., Vasey, H., & Delmas, P. D. (1990) · The Lancet · doi:10.1016/0140-6736(90)91073-j · Cited by 825
Anorexia of aging: physiologic and pathologic
Morley, J. (1997) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/66.4.760 · Cited by 763
Untitled work
(1996) · PubMed · Cited by 705
Low ratio of fat to carbohydrate oxidation as predictor of weight gain: study of 24-h RQ
Zurlo, F., Lillioja, S., Esposito-Del Puente, A., Nyomba, B. L., Raz, I., Saad, M. F., Swinburn, B. A., Knowler, W. C., Bogardus, C., & Ravussin, E. (1990) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1990.259.5.e650 · Cited by 705
High glycemic index foods, overeating, and obesity
Ludwig, D. S., Majzoub, J. A., Al-Zahrani, A., Dallal, G. E., Blanco, I., & Roberts, S. B. (1999) · Pediatrics · doi:10.1542/peds.103.3.e26 · Cited by 699 · cited 1×
“Several models of energy regulation (43, 47, 90) postulate a central role for substrate availability in energy regulation, and recent work on blood glucose and hunger has supported the concept of a role for low blood glucose in initiation of hunger signals in young adults (20, 82, 98, 127).”
BackgroundSelf-citation
The physiology of motivation.
Stellar, E. (1954) · Psychological Review · doi:10.1037/h0060347 · Cited by 671
Glucostatic Mechanism of Regulation of Food Intake
Mayer, J. (1953) · New England Journal of Medicine · doi:10.1056/nejm195307022490104 · Cited by 666
Neural control of the endocrine pancreas.
Woods, S. C., & Porte, D. (1974) · Physiological Reviews · doi:10.1152/physrev.1974.54.3.596 · Cited by 630
Cholecystokinin elicits the complete behavioral sequence of satiety in rats.
Antin, J., Gibbs, J., Holt, J., Young, R. C., & Smith, G. P. (1975) · Journal of Comparative and Physiological Psychology · doi:10.1037/h0077040 · Cited by 613
Variety in a meal enhances food intake in man
Rolls, B. J., Rowe, E. A., Rolls, E. T., Kingston, B., Megson, A., & Gunary, R. (1981) · Physiology & Behavior · doi:10.1016/0031-9384(81)90014-7 · Cited by 607
Measurement of Energy Expenditure in Free-Living Humans by Using Doubly Labeled Water
Schoeller, D. A. (1988) · The Journal of Nutrition · doi:10.1093/jn/118.11.1278 · Cited by 602
The taste reactivity test. II. Mimetic responses to gustatory stimuli in chronic thalamic and chronic decerebrate rats
Grill, H. J., & Norgren, R. (1978) · Brain Research · doi:10.1016/0006-8993(78)90569-3 · Cited by 588
Taste and Smell Losses in Normal Aging and Disease
Schiffman, S. S. (1997) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.1997.03550160077042 · Cited by 563
A reanalysis of the factors influencing basal metabolic rate in normal adults
Cunningham, J. J. (1980) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/33.11.2372 · Cited by 545
The Work of the Digestive Glands
Pavlov, I. (2023) · Scientific and Medical Knowledge Production, 1796-1918 · doi:10.4324/9781003009405-20 · Cited by 528
Muscle triglyceride utilization during exercise: effect of training
Hurley, B. F., Nemeth, P. M., Martin, W. H., Hagberg, J. M., Dalsky, G. P., & Holloszy, J. O. (1986) · Journal of Applied Physiology · doi:10.1152/jappl.1986.60.2.562 · Cited by 522
Dietary fat and the regulation of energy intake in human subjects
Lissner, L., Levitsky, D. A., Strupp, B. J., Kalkwarf, H. J., & Roe, D. A. (1987) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/46.6.886 · Cited by 501
Apoptosis: mechanisms and clinical implications
Kam, P. C. A., & Ferch, N. I. (2000) · Anaesthesia · doi:10.1046/j.1365-2044.2000.01554.x · Cited by 455
Percentage of body fat and body mass index are associated with mobility limitations in people aged 70 and older from NHANES III
Davison, K. K., Ford, E. S., Cogswell, M. E., & Dietz, W. H. (2002) · Journal of the American Geriatrics Society · doi:10.1046/j.1532-5415.2002.50508.x · Cited by 435
Measurement of Total Carbon Dioxide Production by Means of D2O18
Lifson, N., Gordon, G. B., & McClintock, R. (1955) · Journal of Applied Physiology · doi:10.1152/jappl.1955.7.6.704 · Cited by 428
Eating out in America, 1987–2000: trends and nutritional correlates
Kant, A. K., & Graubard, B. I. (2004) · Preventive Medicine · doi:10.1016/j.ypmed.2003.10.004 · Cited by 427
Dietary variety within food groups: association with energy intake and body fatness in men and women
McCrory, M. A., Fuss, P. J., McCallum, J. E., Yao, M., Vinken, A. G., Hays, N. P., & Roberts, S. B. (1999) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/69.3.440 · Cited by 423
Self-citation
Laboratory animals exhibiting obesity and diabetes syndromes
Herberg, L., & Coleman, D. L. (1977) · Metabolism · doi:10.1016/0026-0495(77)90128-7 · Cited by 420
Control of Food Intake in Older Men
Roberts, S. B. (1994) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.1994.03520200057036 · Cited by 419
Self-citation
Dietary Compensation by Humans for Supplemental Energy Provided as Ethanol or Carbohydrate in Fluids
Mattes, R. D. (1996) · Physiology & Behavior · doi:10.1016/0031-9384(95)02007-1 · Cited by 403
Effect of muscle mass decrease on age-related BMR changes
Tzankoff, S. P., & Norris, A. H. (1977) · Journal of Applied Physiology · doi:10.1152/jappl.1977.43.6.1001 · Cited by 401
Anorexia in the elderly
Morley, J. E., & Silver, A. J. (1988) · Neurobiology of Aging · doi:10.1016/s0197-4580(88)80004-6 · Cited by 386
High-glycemic Index Foods, Hunger, and Obesity: Is There a Connection?
Roberts, S. B. (2009) · Nutrition Reviews · doi:10.1111/j.1753-4887.2000.tb01855.x · Cited by 356 · cited 1×
“Several models of energy regulation (43, 47, 90) postulate a central role for substrate availability in energy regulation, and recent work on blood glucose and hunger has supported the concept of a role for low blood glucose in initiation of hunger signals in young adults (20, 82, 98, 127).”
BackgroundSelf-citation
Failure of dietary fat intake to promote fat oxidation: a factor favoring the development of obesity
Schutz, Y., Flatt, J. P., & Jéquier, E. (1989) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/50.2.307 · Cited by 349
Insulin Action and Age: European Group for the Study of Insulin Resistance (EGIR)
Ferrannini, E., Vichi, S., Beck-Nielsen, H., Laakso, M., Paolisso, L., Smith, G., & European Group for the Study of Insulin Resistance (1996) · Diabetes · doi:10.2337/diab.45.7.947 · Cited by 343
Model for the regulation of energy balance and adiposity by the central nervous system
Schwartz, M. W., Baskin, D. G., Kaiyala, K. J., & Woods, S. C. (1999) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/69.4.584 · Cited by 325
Overeating in America: Association between Restaurant Food Consumption and Body Fatness in Healthy Adult Men and Women Ages 19 to 80
McCrory, M. A., Fuss, P. J., Hays, N. P., Vinken, A. G., Greenberg, A. S., & Roberts, S. B. (1999) · Obesity Research · doi:10.1002/j.1550-8528.1999.tb00715.x · Cited by 314
Self-citation
Evidence for the anorexia of aging: gastrointestinal transit and hunger in healthy elderly vs. young adults
Clarkston, W. K., Pantano, M. M., Morley, J. E., Horowitz, M., Littlefield, J. M., & Burton, F. R. (1997) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1997.272.1.r243 · Cited by 296
Spontaneous meal patterns of humans: influence of the presence of other people
de Castro, J. M., & de Castro, E. S. (1989) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/50.2.237 · Cited by 279
Reduced nutritional status in an elderly population (> 70 y) is probable before disease and possibly contributes to the development of disease
Mowé, M., Bøhmer, T., & Kindt, E. (1994) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/59.2.317 · Cited by 274
Relationship Between Serum Amino Acid Concentration and Fluctuations in Appetite
Mellinkoff, S. M., Frankland, M., Boyle, D., & Greipel, M. (1956) · Journal of Applied Physiology · doi:10.1152/jappl.1956.8.5.535 · Cited by 274
Dietary fat, carbohydrate balance, and weight maintenance: effects of exercise
Flatt, J. P. (1987) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/45.1.296 · Cited by 269
Acute Hyperinsulinemia and Its Reversal by Vagotomy after Lesions of the Ventromedial Hypothalamus in Anesthetized Rats*
BERTHOUD, H. R., & JEANRENAUD, B. (1979) · Endocrinology · doi:10.1210/endo-105-1-146 · Cited by 266
Inaccuracies in self-reported intake identified by comparison with the doubly labelled water method
Schoeller, D. A., Bandini, L. G., & Dietz, W. H. (1990) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/y90-143 · Cited by 266
Basal metabolism and age of adult man
Keys, A., Taylor, H. L., & Grande, F. (1973) · Metabolism · doi:10.1016/0026-0495(73)90071-1 · Cited by 262
Effect of age on body composition and resting metabolic rate
Fukagawa, N. K., Bandini, L. G., & Young, J. B. (1990) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1990.259.2.e233 · Cited by 261
Diet-induced thermogenesis measured over a whole day in obese and nonobese women
Schutz, Y., Bessard, T., & Jéquier, E. (1984) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/40.3.542 · Cited by 260
A fall in blood glucose level precedes meal onset in free-feeding rats
Louis-Sylvestre, J., & Le Magnen, J. (1980) · Neuroscience & Biobehavioral Reviews · doi:10.1016/0149-7634(80)90041-x · Cited by 249
Functional Neurobiology of Aging
(2001) · Elsevier eBooks · doi:10.1016/b978-0-12-351830-9.x5000-8 · Cited by 248
Effects of age on concentrations of plasma cholecystokinin, glucagon-like peptide 1, and peptide YY and their relation to appetite and pyloric motility
MacIntosh, C. G., Andrews, J. M., Jones, K. L., Wishart, J. M., Morris, H. A., Jansen, J. B., Morley, J. E., Horowitz, M., & Chapman, I. M. (1999) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/69.5.999 · Cited by 248
Within- and between-subject variation in energy expenditure measured by the doubly-labelled water technique: implications for validating reported dietary energy intake
Black, A., & Cole, T. (2000) · European Journal of Clinical Nutrition · doi:10.1038/sj.ejcn.1600970 · Cited by 247
Effect of flavor enhancement of foods for the elderly on nutritional status: Food intake, biochemical indices, and anthropometric measures
Schiffman, S. S., & Warwick, Z. S. (1993) · Physiology & Behavior · doi:10.1016/0031-9384(93)90224-4 · Cited by 247
Aging and energy expenditure
Vaughan, L., Zurlo, F., & Ravussin, E. (1991) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/53.4.821 · Cited by 239
Specific loss of the hypoglycemic control of feeding in recovered lateral rats
Epstein, A., & Teitelbaum, P. (1967) · American Journal of Physiology-Legacy Content · doi:10.1152/ajplegacy.1967.213.5.1159 · Cited by 224
Effect of Exogenous Cholecystokinin (CCK)-8 on Food Intake and Plasma CCK, Leptin, and Insulin Concentrations in Older and Young Adults: Evidence for Increased CCK Activity as a Cause of the Anorexia of Aging
MacIntosh, C. G. (2001) · Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.86.12.5830 · Cited by 223
Body Weight as a Risk Factor in the Elderly
Tayback, M. (1990) · Archives of Internal Medicine · doi:10.1001/archinte.150.5.1065 · Cited by 222
Effect of intensity of physical activity on body fatness and fat distribution
Tremblay, A., Després, J., Leblanc, C., Craig, C., Ferris, B., Stephens, T., & Bouchard, C. (1990) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/51.2.153 · Cited by 219
Infusion of 2-Deoxy-D-Glucose into the Hepatic-Portal System Causes Eating: Evidence for Peripheral Glucoreceptors
Novin, D., VanderWeele, D. A., & Rezek, M. (1973) · Science · doi:10.1126/science.181.4102.858 · Cited by 218
Effect of age on gastric emptying of liquid-solid meals in man
Moore, J. G., Tweedy, C., Christian, P. E., & Datz, F. L. (1983) · Digestive Diseases and Sciences · doi:10.1007/bf01324951 · Cited by 216
Age-related impairments in the regulation of food intake
Rolls, B., Dimeo, K., & Shide, D. (1995) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/62.5.923 · Cited by 210
Taste Thresholds: Quality Specific Variation with Human Aging
Weiffenbach, J. M., Baum, B. J., & Burghauser, R. (1982) · Journal of Gerontology · doi:10.1093/geronj/37.3.372 · Cited by 209
Hyperalimentation in Normal Animals Produced by Protamine Insulin
MacKay, E. M., Callaway, J. W., & Barnes, R. H. (1940) · The Journal of Nutrition · doi:10.1093/jn/20.1.59 · Cited by 203
Importance of nutrient balance in body weight regulation
Flatt, J. P. (1988) · Diabetes/Metabolism Reviews · doi:10.1002/dmr.5610040603 · Cited by 195
Correlation between echographic gastric emptying and appetite: influence of psyllium.
Bergmann, J. F., Chassany, O., Petit, A., Triki, R., Caulin, C., & Segrestaa, J. M. (1992) · Gut · doi:10.1136/gut.33.8.1042 · Cited by 190
Effects of age on sensory-specific satiety
Rolls, B., & McDermott, T. (1991) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/54.6.988 · Cited by 188
Food Recognition by the Elderly
Schiffman, S. (1977) · Journal of Gerontology · doi:10.1093/geronj/32.5.586 · Cited by 185
Energy intake and appetite are related to antral area in healthy young and older subjects
Sturm, K., Parker, B., Wishart, J., Feinle-Bisset, C., Jones, K. L., Chapman, I., & Horowitz, M. (2004) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/80.3.656 · Cited by 184
The metabolic basis of dual periodicity of feeding in rats
Le Magnen, J. (1981) · Behavioral and Brain Sciences · doi:10.1017/s0140525x00000236 · Cited by 183
Variety in the diet enhances intake in a meal and contributes to the development of obesity in the rat
Rolls, B. J., Van Duijvenvoorde, P. M., & Rowe, E. A. (1983) · Physiology & Behavior · doi:10.1016/0031-9384(83)90091-4 · Cited by 179
Glucose-sensitive afferent nerve fibers in the liver and their role in food intake and blood glucose regulation
Niijima, A. (1983) · Journal of the Autonomic Nervous System · doi:10.1016/0165-1838(83)90142-x · Cited by 178
Physical Activity and Parameters of Aging: A Physiological Perspective
Westerterp, K. R., & Meijer, E. P. (2001) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/56.suppl_2.7 · Cited by 174
Effect of Glucagon on Food Intake and Body Weight in Man
Schulman, J. L., Carleton, J. L., Whitney, G., & Whitehorn, J. C. (1957) · Journal of Applied Physiology · doi:10.1152/jappl.1957.11.3.419 · Cited by 174
Central insulin enhances sensitivity to cholecystokinin
RIEDY, C., CHAVEZ, M., FIGLEWICZ, D., & WOODS, S. (1995) · Physiology & Behavior · doi:10.1016/0031-9384(95)00108-u · Cited by 173
Dietary Determinants of Energy Intake and Weight Regulation in Healthy Adults
McCrory, M. A., Fuss, P. J., Saltzman, E., & Roberts, S. B. (2000) · The Journal of Nutrition · doi:10.1093/jn/130.2.276s · Cited by 172
Self-citation
Vagal sensory neurons are required for lipoprivic but not glucoprivic feeding in rats
Ritter, S., & Taylor, J. S. (1990) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1990.258.6.r1395 · Cited by 172
Gastric Emptying Rate in the Elderly: Implications for Drug Therapy
EVANS, M. A., TRIGGS, E. J., CHEUNG, M., BROE, G. A., & CREASEY, H. (1981) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1981.tb01766.x · Cited by 170
Gastrointestinal correlates of the development of hunger in man
Sepple, C. P., & Read, N. W. (1989) · Appetite · doi:10.1016/0195-6663(89)90011-1 · Cited by 168
Counterregulatory hormone responses to hypoglycemia in the elderly patient with diabetes
Meneilly, G. S., Cheung, E., & Tuokko, H. (1994) · Diabetes · doi:10.2337/diab.43.3.403 · Cited by 167
Human eating: evidence for a physiological basis using a modified paradigm
Campfield, L. A., Smith, F. J., Rosenbaum, M., & Hirsch, J. (1996) · Neuroscience & Biobehavioral Reviews · doi:10.1016/0149-7634(95)00043-e · Cited by 167
Counterregulatory hormone responses to hypoglycemia in the elderly patient with diabetes
Meneilly, G. S., Cheung, E., & Tuokko, H. (1994) · Diabetes · doi:10.2337/diabetes.43.3.403 · Cited by 167
Metering of intravenous versus oral nutrients and regulation of energy balance
Nicolaidis, S., & Rowland, N. (1976) · American Journal of Physiology-Legacy Content · doi:10.1152/ajplegacy.1976.231.3.661 · Cited by 167
Glucose as a Regulator of Neuronal Activity
(1983) · Advances in Metabolic Disorders · doi:10.1016/b978-0-12-027310-2.50008-6 · Cited by 166
Salivation to the Sight and Thought of Food: A New Measure of Appetite*
Wooley, S. C., & Wooley, O. W. (1973) · Psychosomatic Medicine · doi:10.1097/00006842-197303000-00006 · Cited by 162
Age and sex effects on energy expenditure
Klausen, B., Toubro, S., & Astrup, A. (1997) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/65.4.895 · Cited by 161
Conditioned insulin secretion and meal feeding in rats.
Woods, S. C., Vasselli, J. R., Kaestner, E., Szakmary, G. A., Milburn, P., & Vitiello, M. V. (1977) · Journal of Comparative and Physiological Psychology · doi:10.1037/h0077307 · Cited by 160
Appetite, Food Intake, and Plasma Concentrations of Cholecystokinin, Ghrelin, and Other Gastrointestinal Hormones in Undernourished Older Women and Well-Nourished Young and Older Women
Sturm, K., MacIntosh, C. G., Parker, B. A., Wishart, J., Horowitz, M., & Chapman, I. M. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2002-021656 · Cited by 160
On-line continuous measurement of blood glucose and meal pattern in free-feeding rats: The role of glucose in meal initiation
Campfield, L. A., Brandon, P., & Smith, F. J. (1985) · Brain Research Bulletin · doi:10.1016/0361-9230(85)90110-8 · Cited by 160
Glucose-induced Thermogenesis in Nondiabetic and Diabetic Obese Subjects
Golay, A., Schutz, Y., Meyer, H. U., Thiébaud, D., Curchod, B., Maeder, E., Felber, J.-P., & Jéquier, E. (1982) · Diabetes · doi:10.2337/diacare.31.11.1023 · Cited by 160
The Mechanism of Satiety: Effect of Glucagon on Gastric Hunger Contractions in Man.
Stunkard, A. J., Van Itallie, T. B., & Reis, B. B. (1955) · Experimental Biology and Medicine · doi:10.3181/00379727-89-21776 · Cited by 160
Integrated metabolic control of food intake
Friedman, M. I., Tordoff, M. G., & Ramírez, I. (1986) · Brain Research Bulletin · doi:10.1016/0361-9230(86)90099-7 · Cited by 157
Blood glucose patterns and appetite in time-blinded humans: carbohydrate versus fat
Melanson, K. J., Westerterp‐Plantenga, M. S., Saris, W. H. M., Smith, F. J., & Campfield, L. A. (1999) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1999.277.2.r337 · Cited by 155
Impaired leptin responsiveness in aged rats.
Scarpace, P. J., Matheny, M. E., Moore, R. L., & Tümer, N. (2000) · Diabetes · doi:10.2337/diabetes.49.3.431 · Cited by 154
Strategies and Potential Molecular Targets for Obesity Treatment
Campfield, L. A., Smith, F. J., & Burn, P. (1998) · Science · doi:10.1126/science.280.5368.1383 · Cited by 153
Effects of hypothalamic lesion on pancreatic autonomic nerve activity in the rat
Yoshimatsu, H., Niijima, A., Oomura, Y., Yamabe, K., & Katafuchi, T. (1984) · Brain Research · doi:10.1016/0006-8993(84)90222-1 · Cited by 152
The Age-Related Decline in Resting Energy Expenditure in Humans Is Due to the Loss of Fat-Free Mass and to Alterations in Its Metabolically Active Components
Bosy‐Westphal, A., Eichhorn, C., Kutzner, D., Illner, K., Heller, M., & Müller, M. J. (2003) · Journal of Nutrition · doi:10.1093/jn/133.7.2356 · Cited by 151
Age, sex and laterality effects on cerebral glucose metabolism in healthy adults
Willis, M. W., Ketter, T. A., Kimbrell, T. A., George, M. S., Herscovitch, P., Danielson, A. L., Benson, B. E., & Post, R. M. (2002) · Psychiatry Research Neuroimaging · doi:10.1016/s0925-4927(01)00126-3 · Cited by 150
The numerical and topographical relations of taste buds to human circumv allate papillae throughout the life span
Arey, L. B., Tremaine, M. J., & Monzingo, F. L. (1935) · The Anatomical Record · doi:10.1002/ar.1090640103 · Cited by 148
Blood Glucose Dynamics and Control of Meal Initiation: A Pattern Detection and Recognition Theory
Campfield, L. A., & Smith, F. J. (2003) · Physiological Reviews · doi:10.1152/physrev.00019.2002 · Cited by 147
Impaired Sensory Functioning in Elders: The Relation With Its Potential Determinants and Nutritional Intake
de Jong, N., Mulder, I. E., de Graaf, C., et al. (1999) · The Journals of Gerontology Series A · doi:10.1093/gerona/54.8.b324 · Cited by 144
Weight Loss and Mortality in a National Cohort of Adults, 1971–1987
Pamuk, E. R., Williamson, D. F., Madans, J. H., Serdula, M. K., Kleinman, J. C., & Byers, T. (1992) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a116548 · Cited by 139
The effect of posture on gastric emptying and intragastric distribution of oil and aqueous meal components and appetite
Horowitz, M., Jones, K. L., Edelbroek, M. A. L., Smout, A. J. P. M., & Read, N. W. (1993) · Gastroenterology · doi:10.1016/0016-5085(93)90711-k · Cited by 135
THE FATE OF UTILIZED MOLECULAR OXYGEN AND THE SOURCE OF THE OXYGEN OF RESPIRATORY CARBON DIOXIDE, STUDIED WITH THE AID OF HEAVY OXYGEN
Lifson, N., Gordon, G. B., Visscher, M. B., & Nier, A. O. C. (1949) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)56700-4 · Cited by 133
Plasma insulin and the time pattern of feeding in the rat
STRUBBE, J. H., Steffens, A. B., & de Ruiter, L. (1977) · Physiology & Behavior · doi:10.1016/0031-9384(77)90097-x · Cited by 133
Calorie and Nutrient Intakes of Elderly and Young Subjects Measured Under Identical Conditions
Wurtman, J. J., Lieberman, H. R., Tsay, R. H., Nader, T. M. A., & Chew, B. (1988) · Journal of Gerontology · doi:10.1093/geronj/43.6.b174 · Cited by 133
Satiating Effect of Cholecystokinina
Smith, G. P., & Gibbs, J. (1994) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1994.tb44071.x · Cited by 131
Effects of small intestinal nutrient infusion on appetite and pyloric motility are modified by age
Cook, C. G., Andrews, J. M., Jones, K. L., Wittert, G., Chapman, I. M., Morley, J. E., & Horowitz, M. (1997) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1997.273.2.r755 · Cited by 130
Altered responses to hypoglycemia of healthy elderly people
Meneilly, G. S., Cheung, E., & Tuokko, H. A. (1994) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.78.6.8200936 · Cited by 122
Neurobiology of Feeding and Nutrition
(1992) · Elsevier eBooks · doi:10.1016/b978-0-124-43340-3.x5001-6 · Cited by 118
Role of palatability on meal-induced thermogenesis in human subjects
LEBLANC, J., & Brondel, L. (1985) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1985.248.3.e333 · Cited by 117
Relation of Age and Physical Exercise Status on Metabolic Rate in Younger and Older Healthy Men
Poehlman, É. T., Melby, C. L., & Badylak, S. F. (1991) · Journal of Gerontology · doi:10.1093/geronj/46.2.b54 · Cited by 117
Control of energy intake by energy metabolism
Friedman, M. I. (1995) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/62.5.1096s · Cited by 114
Prompted Voiding Treatment of Urinary Incontinence in Nursing Home Patients
Schnelle, J. F., Traughber, B., Sowell, V. A., Newman, D. R., Petrilli, C. O., & Ory, M. G. (1989) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1989.tb06919.x · Cited by 112
Inhibition of gold thioglucose-induced hypothalamic obesity by glucose analogues
Likuski, H., Debons, A., & Cloutier, R. (1967) · American Journal of Physiology-Legacy Content · doi:10.1152/ajplegacy.1967.212.3.669 · Cited by 111
Dietary Variety Predicts Low Body Mass Indexand Inadequate Macronutrient and MicronutrientIntakes in Community-Dwelling Older Adults
Roberts, S. B., Hajduk, C. L., Howarth, N. C., Russell, R., & McCrory, M. A. (2005) · The Journals of Gerontology Series A · doi:10.1093/gerona/60.5.613 · Cited by 110
Self-citation
The psychobiology of meals
Woods, S. C., & STRUBBE, J. H. (1994) · Psychonomic Bulletin & Review · doi:10.3758/bf03200770 · Cited by 107
Disruption of the Relationship between Fat Content and Leptin Levels with Aging in Humans
Møller, N., O’Brien, P. C., & Nair, K. S. (1998) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.83.3.4620 · Cited by 107
Role of Brown Adipose Tissue Thermogenesis in Control of Thermoregulatory Feeding in Rats: A New Hypothesis That Links Thermostatic and Glucostatic Hypotheses for Control of Food Intake
Himms‐Hagen, J. (1995) · Experimental Biology and Medicine · doi:10.3181/00379727-208-43847a · Cited by 106
Resting metabolic rate and diet-induced thermogenesis in young and elderly subjects: relationship with body composition, fat distribution, and physical activity level
Visser, M., Deurenberg, P., van Staveren, W., & Hautvast, J. (1995) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/61.4.772 · Cited by 105
Blood glucose and meal patterns in time-blinded males, after aspartame, carbohydrate, and fat consumption, in relation to sweetness perception
Melanson, K. J., Westerterp‐Plantenga, M. S., Campfield, L. A., & Saris, W. H. M. (1999) · British Journal Of Nutrition · doi:10.1017/s0007114599001695 · Cited by 103
Depressive symptoms and weight change in a national cohort of adults.
DiPietro, L., Anda, R. F., Df, W., & Stunkard, A. J. (1992) · PubMed · Cited by 99
The thermic effect of feeding in older men: the importance of the sympathetic nervous system
Schwartz, R. S., Jaeger, L. F., & Veith, R. C. (1990) · Metabolism · doi:10.1016/0026-0495(90)90109-p · Cited by 98
Decreased Discrimination of Food Odors in the Elderly
Schiffman, S. S., & Pasternak, M. (1979) · Journal of Gerontology · doi:10.1093/geronj/34.1.73 · Cited by 98
Within-meal gut feedback signaling
Moran, T. H., Ladenheim, E. E., & Schwartz, G. (2001) · International Journal of Obesity · doi:10.1038/sj.ijo.0801910 · Cited by 95
Cross-Sectional and Longitudinal Analysis of Age-Associated Changes in Body Composition of Male Brown Norway Rats: Association of Serum Leptin Levels With Peripheral Adiposity
Wolden‐Hanson, T., Marck, B. T., Smith, L., & Matsumoto, A. M. (1999) · The Journals of Gerontology Series A · doi:10.1093/gerona/54.3.b99 · Cited by 94
Hormone action during aging: Alterations and mechanisms
Roth, G. S. (1979) · Mechanisms of Ageing and Development · doi:10.1016/0047-6374(79)90090-3 · Cited by 94
Taste and smell sensations enhance the satiating effect of both a high-carbohydrate and a high-fat meal in humans
Warwick, Z. S., HALL, W. G., Pappas, T. N., & Schiffman, S. S. (1993) · Physiology & Behavior · doi:10.1016/0031-9384(93)90153-7 · Cited by 93
Pancreatic glucagon signals postprandial satiety
Geary, N. (1990) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(05)80042-9 · Cited by 92
Hepatic versus cerebral origin of stimulus for feeding induced by 2-deoxy-{d}-glucose in rats.
Stricker, E. M., & Rowland, N. E. (1978) · Journal of Comparative and Physiological Psychology · doi:10.1037/h0077454 · Cited by 91
Free fatty acid and glucose metabolism in human aging: evidence for operation of the Randle cycle
Bonadonna, R. C., Groop, L., Simonson, D. C., & DeFronzo, R. A. (1994) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1994.266.3.e501 · Cited by 90
Influence of age on energy requirements
Roberts, S. B., Fuss, P., Heyman, M., & Young, V. R. (1995) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/62.5.1053s · Cited by 89
Self-citation
Characterizing consumption patterns by food frequency methods: Core foods and variety of foods in diets of older Americans
Fanelli, M. T., & Stevenhagen, K. J. (1985) · Journal of the American Dietetic Association · doi:10.1016/s0002-8223(21)03842-6 · Cited by 89
Enegy expenditure, physical activity and basal metabolic rate of elderly subjects
Pannemans, D. L. E., & Westerterp, K. R. (1995) · British Journal Of Nutrition · doi:10.1079/bjn19950059 · Cited by 88
McCollum Award Lecture, 1995: diet, lifestyle, and weight maintenance
Flatt, J. (1995) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/62.4.820 · Cited by 86
Effects of a 6-Week Hypocaloric Diet on Changes in Body Composition, Hunger, and Subsequent Weight Regain in Healthy Young and Older Adults
Moriguti, J. C., Das, S. K., Saltzman, E. J., Corrales, A., McCrory, M. A., Greenberg, A. S., & Roberts, S. B. (2000) · The Journals of Gerontology Series A · doi:10.1093/gerona/55.12.b580 · Cited by 86
Self-citation
What are the dietary energy needs of elderly adults?
Roberts, S. B., Young, V. R., Fuss, P., Heyman, M. B., FIATARONE, M. A., Dallal, G. E., Cortiella, J., & Evans, W. J. (1992) · PubMed · Cited by 84
Self-citation
Effect of electrolytic and neurotoxic lesions of the median raphe nucleus on anxiety and stress
Andrade, T. G. C. S., & Graeff, F. G. (2001) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(01)00512-3 · Cited by 83
Neural Mechanisms in the Control of Blood Glucose Concentration
Niijima, A. (1989) · Journal of Nutrition · doi:10.1093/jn/119.6.833 · Cited by 82
Resistance to the anorexic and thermogenic effects of centrally administrated leptin in obese aged rats
Shek, E. W., & Scarpace, P. J. (2000) · Regulatory Peptides · doi:10.1016/s0167-0115(00)00151-8 · Cited by 82
Disruption of the Relationship between Fat Content and Leptin Levels with Aging in Humans
Møller, N. (1998) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.83.3.931 · Cited by 82
Reduced whole-body fat oxidation in women and in the elderly
Levadoux, E., Morio, B., Montaurier, C., Puissant, V, Boirie, Y., Fellmann, N., Picard, B., Rousset, P., Beaufrere, B., & Ritz, P. (2001) · International Journal of Obesity · doi:10.1038/sj.ijo.0801530 · Cited by 80
Consequences of Ventromedial Hypothalamic Lesions upon Insulin and Glucagon Secretion by Subsequently Isolated Perfused Pancreases in the Rat
Rohner-Jeanrenaud, F., & Jeanrenaud, B. (1980) · Journal of Clinical Investigation · doi:10.1172/jci109744 · Cited by 80
Anticipatory salivary flow to the sight of different foods
Christensen, C. M., & Navazesh, M. (1984) · Appetite · doi:10.1016/s0195-6663(84)80003-3 · Cited by 79
Circadian sleep and feeding patterns in the rat: possible dependence on lipogenesis and lipolysis
Danguir, J., & Nicolaïdis, S. (1980) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1980.238.3.e223 · Cited by 78
Energy Expenditure and Requirements in Aging Humans ,
Poehlman, É. T. (1992) · Journal of Nutrition · doi:10.1093/jn/122.11.2057 · Cited by 77
Use of the doubly labeled water method for measurement of energy expenditure, total body water, water intake, and metabolizable energy intake in humans and small animals
Roberts, S. B. (1989) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/y89-189 · Cited by 77
Self-citation
Fasting-induced increases in food intake and neuropeptide Y gene expression are attenuated in aging male brown Norway rats
Gruenewald, D. A., Marck, B. T., & Matsumoto, A. M. (1996) · Endocrinology · doi:10.1210/endo.137.10.8828508 · Cited by 76
Dietary energy requirements of young and older women determined by using the doubly labeled water method
Sawaya, A. L., Saltzman, E. J., Fuss, P., Young, V. R., & Roberts, S. B. (1995) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/62.2.338 · Cited by 76
Self-citation
Palatability and dietary restraint: Effect on cephalic phase insulin release in women
Teff, K. L., & Engelman, K. (1996) · Physiology & Behavior · doi:10.1016/s0031-9384(96)80033-3 · Cited by 75
Chemical Senses in the Release of Gastric and Pancreatic Secretions
Brand, J. G., Cagan, R. H., & Naim, M. (1982) · Annual Review of Nutrition · doi:10.1146/annurev.nu.02.070182.001341 · Cited by 75
Aging and fasting regulation of leptin and hypothalamic neuropeptide Y gene expression
Li, H., Matheny, M. E., Tümer, N., & Scarpace, P. J. (1998) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1998.275.3.e405 · Cited by 75
Arleriovenous Glucose Differences , METABOLIC HYPOGLYCEMIA AND FOOD INTAKE in Man
Itallie, T. B. V., Beaudoin, R., & Mayer, J. (1953) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/1.3.208 · Cited by 74
Effect of gastrointestinal peptides on ingestion in old and young mice
Silver, A. J., Flood, J. F., & Morley, J. E. (1988) · Peptides · doi:10.1016/0196-9781(88)90254-9 · Cited by 74
Thresholds of food odors in the elderly
Schiffman, S. S., Moss, J., & Erickson, R. P. (1976) · Experimental Aging Research · doi:10.1080/03610737608257997 · Cited by 74
Basal fat oxidation decreases with aging in women
Calles-Escandón, J., Arciero, P. J., Gardner, A. W., Bauman, C., & Poehlman, É. T. (1995) · Journal of Applied Physiology · doi:10.1152/jappl.1995.78.1.266 · Cited by 74
Sensory versus dietary factors in cafeteria-induced overweight
LOUIS-SYLVESTRE, J., Giachetti, I., & Magnen, J. L. (1984) · Physiology & Behavior · doi:10.1016/0031-9384(84)90275-0 · Cited by 73
Variation in total energy expenditure in young healthy free-living men
Goran, M. I., Beer, W. H., Wolfe, R. R., Poehlman, É. T., & Young, V. R. (1993) · Metabolism · doi:10.1016/0026-0495(93)90108-z · Cited by 71
A Quantitative Study of the Gastric Secretory Response to Sham Feeding in a Human Subject
Janowitz, H. D., Hollander, F., Orringer, D., Levy, M. H., WINKELSTEIN, A., Kaufman, M. R., & Margolin, S. G. (1950) · Gastroenterology · doi:10.1016/s0016-5085(19)36597-7 · Cited by 71
Energy balance in healthy elderly women
Reilly, J. J., Lord, A. C., Bunker, V. W., Prentice, A. M., Coward, W. A., Thomas, A. J., & BRIGGS, R. S. J. (1993) · British Journal Of Nutrition · doi:10.1079/bjn19930005 · Cited by 70
Attenuated Glucose Recovery from Hypoglycemia in the Elderly
Marker, J. C., Cryer, P. E., & Clutter, W. E. (1992) · Diabetes · doi:10.2337/diab.41.6.671 · Cited by 70
Reduced awareness of hypoglycaemia in the elderly despite an intact counter-regulatory response
Brierley, E. J., Broughton, D., James, O., & Alberti, K. G. M. M. (1995) · QJM · doi:10.1093/oxfordjournals.qjmed.a069086 · Cited by 69
Innervation of the liver and glucoregulation: Roles of the hypothalamus and autonomic nerves
Shimazu, T. (1996) · Nutrition · doi:10.1016/0899-9007(96)00060-3 · Cited by 68
An autonomic hypothesis for hypothalamic obesity
Inoue, S., & Bray, G. A. (1979) · Life Sciences · doi:10.1016/0024-3205(79)90549-6 · Cited by 67
Inhibition of feeding by a nitric oxide synthase inhibitor: effects of aging
Morley, J. E., Kumar, V. B., Mattammal, M. B., Farr, S., Morley, P. M. K., & Flood, J. F. (1996) · European Journal of Pharmacology · doi:10.1016/0014-2999(96)00546-8 · Cited by 67
Temporal Bounds of Post-ingestive Glucose induced Satiety in Man
Booth, D., Campbell, A., & Chase, A. (1970) · Nature · doi:10.1038/2281104a0 · Cited by 66
The different effects of continuous night and day-time insulin infusion on the meal pattern of normal rats: Comparison with the meal pattern of hyperphagic hypothalamic rats
Larue‐Achagiotis, C., & Magnen, J. L. (1979) · Physiology & Behavior · doi:10.1016/0031-9384(79)90005-2 · Cited by 66
Parasympathetic involvement in rapid meal-associated conditioned insulin secretion in the rat
Strubbe, J. H. (1992) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1992.263.3.r615 · Cited by 65
Effect of ageing on the gastro-intestinal transit of a lactulose-supplemented mixed solid-liquid meal in humans.
Wegener, M., Börsch, G., Schaffstein, J., Lüth, I., Rickels, R., & Ricken, D. (1988) · Digestion · doi:10.1159/000199606 · Cited by 65
Effects of Age on Energy Expenditure and Substrate Oxidation During Experimental Overfeeding in Healthy Men
Roberts, S. B., Fuss, P., Dallal, G. E., Atkinson, A., Evans, W. J., Joseph, L. J., FIATARONE, M. A., Greenberg, A. S., & Young, V. R. (1996) · The Journals of Gerontology Series A · doi:10.1093/gerona/51a.2.b148 · Cited by 65
Self-citation
Influence of delayed isotopic equilibration in urine on the accuracy of the 2H2 18O method in the elderly
Blanc, S., Colligan, A. S., Trabulsi, J., Harris, T. B., Everhart, J. E., Bauer, D. C., & Schoeller, D. A. (2002) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00743.2001 · Cited by 64
Physiologic Mechanisms in the Development of Starvation Ketosis in Man
Grey, N. J., Karl, I. E., & KIPNIS, D. M. (1975) · Diabetes · doi:10.2337/diab.24.1.10 · Cited by 63
Central leptin gene delivery evokes persistent leptin signal transduction in young and aged-obese rats but physiological responses become attenuated over time in aged-obese rats
Scarpace, P. J., Matheny, M. E., Zhang, Y., Tümer, N., Frase, C. D., Shek, E. W., Hong, B., Prima, V., & Zolotukhin, S. (2002) · Neuropharmacology · doi:10.1016/s0028-3908(02)00003-5 · Cited by 62
Nutrition and the chemical senses in aging: recent advances and current research needs.
Murphy, C., Cain, W. S., & Hegsted, D. M. (1989) · PubMed · Cited by 61
Changes in Taste and Smell: Drug Interactions and Food Preferences
Schiffman, S. S. (2009) · Nutrition Reviews · doi:10.1111/j.1753-4887.1994.tb01439.x · Cited by 60
Effects of xylitol on gastric emptying and food intake
Shafer, R. B., Levine, A. S., MARLETTE, J. M., et al. (1987) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/45.4.744 · Cited by 60
Insulin, Neuropeptide Y, and Food Intake
Schwartz, M. W., Figlewicz, D. P., Woods, S. C., Porte, D., & Baskin, D. G. (1993) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1993.tb26206.x · Cited by 59
Alterations in plasma and cerebrospinal fluid levels of neuropeptides in idiopathic senile anorexia
Martínez, M., Hernánz, Á., Gómez-Cerezo, J. F., Peña, J., Vázquez, J. J., & Arnalich, F. (1993) · Regulatory Peptides · doi:10.1016/0167-0115(93)90432-8 · Cited by 58
Changes in Pattern of Macronutrient Intake During Aging in Male and Female Rats
Veyrat‐Durebex, C., & Alliot, J. (1997) · Physiology & Behavior · doi:10.1016/s0031-9384(97)00304-1 · Cited by 57
Underfeeding and body weight regulation in normal-weight young men
Heyman, M. B., Young, V. R., Fuss, P., Tsay, R. H., Joseph, L. J., & Roberts, S. B. (1992) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1992.263.2.r250 · Cited by 57
Self-citation
Dietary energy requirements of young adult men, determined by using the doubly labeled water method
Roberts, S. B., Heyman, M., Evans, W., Fuss, P., Tsay, R. H., & Young, V. R. (1991) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/54.3.499 · Cited by 57
Self-citation
The effect of gender and body composition method on the apparent decline in lean mass-adjusted resting metabolic rate with age
Roubenoff, R., Hughes, V. A., Dallal, G. E., Nelson, M. E., Morganti, C., Kehayias, J. J., Singh, M. A. F., & Roberts, S. (2000) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/55.12.m757 · Cited by 55
Self-citation
Blunted hypothalamic neuropeptide gene expression in response to fasting, but preservation of feeding responses to AgRP in aging male Brown Norway rats
Wolden‐Hanson, T., Marck, B. T., & Matsumoto, A. M. (2004) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00465.2003 · Cited by 55
Effects of Aging on Energy Requirements and the Control of Food Intake in Men
Holloszy, J. O., & Roberts, S. B. (1995) · The Journals of Gerontology Series A · doi:10.1093/gerona/50a.special_issue.101 · Cited by 55
Self-citation
An Underfeeding Study in Healthy Men and Women Provides Further Evidence of Impaired Regulation of Energy Expenditure in Old Age
Das, S. K., Moriguti, J. C., McCrory, M. A., Saltzman, E. J., Mosunic, C. J., Greenberg, A. S., & Roberts, S. B. (2001) · Journal of Nutrition · doi:10.1093/jn/131.6.1833 · Cited by 55
Self-citation
Feeding and drinking responses to neuropeptide Y injections in the paraventricular hypothalamic nucleus of aged rats
Pich, E. M., Messori, B., Zoli, M., Ferraguti, F., Marrama, P., Biagini, G., Fuxé, K., & Agnati, L. F. (1992) · Brain Research · doi:10.1016/0006-8993(92)90089-r · Cited by 54
Influence of physical activity and dietary restraint on resting energy expenditure in young nonobese females
Poehlman, É. T., Viers, H. F., & Detzer, M. J. (1991) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/y91-049 · Cited by 53

The epidemiology of obesity: the size of the problem
James, W. P. T. (2008) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2008.01922.x · Cited by 786
Scientific Opinion on Dietary Reference Values for energy
EFSA Panel on Dietetic Products, N. A. A. (. (2013) · EFSA Journal · doi:10.2903/j.efsa.2013.3005 · Cited by 258
Adverse renal consequences of obesity
Griffin, K. A., Kramer, H., & Bidani, A. K. (2008) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00324.2007 · Cited by 256
Associations between energy demands, physical activity, and body composition in adult humans between 18 and 96 y of age
Speakman, J. R., & Westerterp, K. R. (2010) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.2009.28540 · Cited by 198
Prohibitin couples diapause signalling to mitochondrial metabolism during ageing in C. elegans
Artal-Sanz, M., & Tavernarakis, N. (2009) · Nature · doi:10.1038/nature08466 · Cited by 196

See all 364

Authors: Roberts, S. B., & Rosenberg, I.
Venue: Physiological Reviews
Publisher: American Physiological Society
Published: 2006-04
Volume: 86
Issue: 2
Pages: 651-667
ISSN: 0031-9333 (ISSN-L)
1522-1210
DOI: 10.1152/physrev.00019.2005
OpenAlex: W2108897517
Cited by: 364
References: 248
FWCI: 1.90
Type: journal article
Language: en
Open access: closed

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.

Nutrition and Aging: Changes in the Regulation of Energy Metabolism With Aging

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Self-check

Citations

Cites

Cited by

Metadata

Record

About these checks

Data sources