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Brain Metabolism during Fasting*
Open accessAbstract
Catheterization of cerebral vessels in three obese patients undergoing 5-6 wk of starvation demonstrated that beta-hydroxybutyrate and acetoacetate replaced glucose as the predominant fuel for brain metabolism. A strikingly low respiratory quotient was also observed, suggesting a carboxylation mechanism as a means of disposing of some of the carbon of the consumed substrates.
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Metadata
- Authors
- Owen, O. E., Morgan, A. P., Kemp, H. G., Sullivan, J. M., Herrera, M. G., & Cahill, G. F.
- Venue
- Journal of Clinical Investigation
- Published
- 1967-10-01
- Volume
- 46
- Issue
- 10
- Pages
- 1589-1595
- ISSN
- 0021-9738 (ISSN-L)
- OpenAlex
- W2104938317
- Cited by
- 1,646
- References
- 1
- FWCI
- 36.87
- Type
- journal article
- Language
- en
- Open access
- bronze
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