Gut microbiota interacts with brain microstructure and function

Human gut microbes associated with obesity

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Postnatal microbial colonization programs the hypothalamic–pituitary–adrenal system for stress response in mice

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The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner

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Obesity is associated with hypothalamic injury in rodents and humans.

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The Intestinal Microbiota Affect Central Levels of Brain-Derived Neurotropic Factor and Behavior in Mice

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Principles and clinical implications of the brain-gut-enteric microbiota axis

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Energy-balance studies reveal associations between gut microbes, caloric load, and nutrient absorption in humans

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Human colonic microbiota associated with diet, obesity and weight loss

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Consumption of fermented milk product with probiotic modulates brain activity

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MetaboAnalyst 2.0--a comprehensive server for metabolomic data analysis

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Exposure to a social stressor alters the structure of the intestinal microbiota: Implications for stressor-induced immunomodulation

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Conserved shifts in the gut microbiota due to gastric bypass reduce host weight and adiposity

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Effects of the probiotic Bifidobacterium infantis in the maternal separation model of depression

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Bacterial infection causes stress-induced memory dysfunction in mice

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Intestinal mucosal adherence and translocation of commensal bacteria at the early onset of type 2 diabetes: molecular mechanisms and probiotic treatment

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A randomized, double-blind, placebo-controlled pilot study of a probiotic in emotional symptoms of chronic fatigue syndrome

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Clinical trial: The effects of a trans-galactooligosaccharide prebiotic on faecal microbiota and symptoms in irritable bowel syndrome

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Quantitative MR Imaging of Brain Iron: A Postmortem Validation Study

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Gut microbiota after gastric bypass in human obesity: increased richness and associations of bacterial genera with adipose tissue genes

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Microbiota controls the homeostasis of glial cells in the gut lamina propria

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The effect of age and non-steroidal anti-inflammatory drugs on human intestinal microbiota composition

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Gut microbiome composition is associated with temperament during early childhood

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Improved memory function 12 weeks after bariatric surgery

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Cognitive Function After Bariatric Surgery: Evidence for Improvement 3 Years After Surgery

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Welcome to the Microgenderome

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Metabolic endotoxemia directly increases the proliferation of adipocyte precursors at the onset of metabolic diseases through a CD14-dependent mechanism

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Cognitive function predicts weight loss after bariatric surgery

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Brain Iron Overload, Insulin Resistance, and Cognitive Performance in Obese Subjects: A Preliminary MRI Case-Control Study

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Evaluation of intelligence in an adolescent bariatric population

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The Microbiota-Gut-Brain Axis

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The brain-gut-microbiome axis

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The Gut–Brain Axis and the Microbiome: Mechanisms and Clinical Implications

Osadchiy, V., Martin, C. R., & Mayer, E. A. (2019) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2018.10.002 · Cited by 555 · see citing works

Infant gut microbiome associated with cognitive development

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Systematic Review of Gut Microbiota and Major Depression

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The microbiome and host behavior

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Role of gut-brain axis, gut microbial composition, and probiotic intervention in Alzheimer's disease

Kesika, P., Suganthy, N., Sivamaruthi, B. S., & Chaiyasut, C. (2021) · Life Sciences · doi:10.1016/j.lfs.2020.118627 · Cited by 479 · see citing works

Nutritional psychiatry: Towards improving mental health by what you eat

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The progress of gut microbiome research related to brain disorders

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Signalling cognition: The gut microbiota and hypothalamic-pituitary-adrenal axis

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Short-Chain Fatty Acids and Human Health: From Metabolic Pathways to Current Therapeutic Implications

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Impact of Metabolic Syndrome on Neuroinflammation and the Blood–Brain Barrier

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The effects of plant-based diets on the body and the brain: a systematic review

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Cross talk: the microbiota and neurodevelopmental disorders

Kelly, J. R., Minuto, C., Cryan, J. F., Clarke, G., & Dinan, T. G. (2017) · Frontiers in Neuroscience · doi:10.3389/fnins.2017.00490 · Cited by 271 · see citing works

The Microbiome in Psychology and Cognitive Neuroscience

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Gut Microbiome–Brain Alliance: A Landscape View into Mental and Gastrointestinal Health and Disorders

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You’ve got male: Sex and the microbiota-gut-brain axis across the lifespan

Jaggar, M., Rea, K., Spichak, S., Dinan, T. G., & Cryan, J. F. (2020) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2019.100815 · Cited by 200 · see citing works

Microbiota-gut-brain axis: relationships among the vagus nerve, gut microbiota, obesity, and diabetes

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Brain structure and response to emotional stimuli as related to gut microbial profiles in healthy women

Tillisch, K., Mayer, E. A., Gupta, A., Gill, Z., Brazeilles, R., Le Nevé, B., van Hylckama Vlieg, J. E. T., Guyonnet, D., Derrien, M., & Labus, J. S. (2017) · Psychosomatic Medicine · doi:10.1097/psy.0000000000000493 · Cited by 185 · see citing works

A psychology of the human brain-gut-microbiome axis

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Annual Research Review: Critical windows – the microbiota-gut-brain axis in neurocognitive development

Cowan, C. S. M., Dinan, T. G., & Cryan, J. F. (2020) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.13156 · Cited by 176 · see citing works

Obesity impairs short-term and working memory through gut microbial metabolism of aromatic amino acids

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Microbiota y diabetes mellitus tipo 2

Muñoz‐Garach, A., Díaz-Perdigones, C. M., & Tinahones, F. J. (2016) · Endocrinología y Nutrición · doi:10.1016/j.endonu.2016.07.008 · Cited by 146 · see citing works

The gut microbiota-brain axis, psychobiotics and its influence on brain and behaviour: a systematic review

Barrio, C., Arias-Sánchez, S., & Martín-Monzón, I. (2022) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2021.105640 · Cited by 143 · see citing works

Diet can impact microbiota composition in children with autism spectrum disorder

Berding, K., & Donovan, S. M. (2018) · Frontiers in Neuroscience · doi:10.3389/fnins.2018.00515 · Cited by 144 · see citing works

The role of the microbiome in the neurobiology of social behaviour

Sarkar, A., Harty, S., Johnson, K. V. ‐., Moeller, A. H., Carmody, R. N., Lehto, S. M., Erdman, S. E., Dunbar, R. I. M., & Burnet, P. W. J. (2020) · Biological Reviews · doi:10.1111/brv.12603 · Cited by 135 · see citing works

Cholesterol metabolism: A review of how ageing disrupts the biological mechanisms responsible for its regulation

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The gut microbiome, mild cognitive impairment, and probiotics: A randomized clinical trial in middle-aged and older adults

Aljumaah, M. R., Bhatia, U., Roach, J., Gunstad, J., & Peril, M. A. A. (2022) · Clinical Nutrition · doi:10.1016/j.clnu.2022.09.012 · Cited by 138 · see citing works

Short chain fatty acids: the messengers from down below

Mansuy‐Aubert, V., & Ravussin, Y. (2023) · Frontiers in Neuroscience · doi:10.3389/fnins.2023.1197759 · Cited by 133 · see citing works

Cognitive Function and the Microbiome

Gareau, M. G. (2016) · International review of neurobiology · doi:10.1016/bs.irn.2016.08.001 · Cited by 131 · see citing works

Mining microbes for mental health: determining the role of microbial metabolic pathways in human brain health and disease

Spichak, S., Bastiaanssen, T. F. S., Berding, K., Vlckova, K., Clarke, G., Dinan, T. G., & Cryan, J. F. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.02.044 · Cited by 127 · see citing works

Self-reported sleep quality is associated with gut microbiome composition in young, healthy individuals: a pilot study

Grosicki, G. J., Riemann, B. L., Flatt, A. A., Valentino, T. R., & Lustgarten, M. S. (2020) · Sleep Medicine · doi:10.1016/j.sleep.2020.04.013 · Cited by 121 · see citing works

The gut-brain vascular axis in neuroinflammation

Carloni, S., & Rescigno, M. (2023) · Seminars in Immunology · doi:10.1016/j.smim.2023.101802 · Cited by 123 · see citing works

Gut microbiota and type 2 diabetes mellitus

Muñoz‐Garach, A., Díaz-Perdigones, C. M., & Tinahones, F. J. (2016) · Endocrinología y Nutrición (English Edition) · doi:10.1016/j.endoen.2016.07.004 · Cited by 118 · see citing works

Effect of gut microbiome modulation on muscle function and cognition: the PROMOTe randomised controlled trial

Lochlainn, M. N., Bowyer, R. C. E., Moll, J. M., García, M. P., Wadge, S., Baleanu, A.-F., Nessa, A., Sheedy, A., Akdag, G., Hart, D. J., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-46116-y · Cited by 112 · see citing works

Effects of the Human Gut Microbiota on Cognitive Performance, Brain Structure and Function: A Narrative Review

Tooley, K. L. (2020) · Nutrients · doi:10.3390/nu12103009 · Cited by 111 · see citing works

Gutsy Moves: The Amygdala as a Critical Node in Microbiota to Brain Signaling

Cowan, C. S. M., Hoban, A. E., Ventura‐Silva, A. P., Dinan, T. G., Clarke, G. A., & Cryan, J. F. (2017) · BioEssays · doi:10.1002/bies.201700172 · Cited by 107 · see citing works

An updated overview on the relationship between human gut microbiome dysbiosis and psychiatric and psychological disorders

Borrego-Ruiz, A., & Borrego, J. J. (2023) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2023.110861 · Cited by 106 · see citing works

Targeting the gut microbiota to influence brain development and function in early life

Wang, S., Harvey, L., Martı́n, R., van der Beek, E. M., Knol, J., Cryan, J. F., & Renes, I. B. (2018) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2018.09.002 · Cited by 92 · see citing works

Roles of Gut Microbiota in the Regulation of Hippocampal Plasticity, Inflammation, and Hippocampus-Dependent Behaviors

Tang, W., Meng, Z., Li, N., Liu, Y., Li, L., Chen, D., & Yang, Y. (2021) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2020.611014 · Cited by 89 · see citing works

The Brain-Gut-Microbiome System: Pathways and Implications for Autism Spectrum Disorder

Chernikova, M. A., Flores, G. D., Kilroy, E., Labus, J. S., Mayer, E. A., & Aziz‐Zadeh, L. (2021) · Nutrients · doi:10.3390/nu13124497 · Cited by 86 · see citing works

Gut microbiome populations are associated with structure-specific changes in white matter architecture

Ong, I. M., Gonzalez, J. G., McIlwain, S. J., Sawin, E. A., Schoen, A. J., Adluru, N., Alexander, A. L., & Yu, J.-P. J. (2018) · Translational Psychiatry · doi:10.1038/s41398-017-0022-5 · Cited by 83 · see citing works

Lactobacillus plantarum DR7 modulated bowel movement and gut microbiota associated with dopamine and serotonin pathways in stressed adults

Liu, G., Chong, H.-X., Chung, F. Y.-L., Li, Y., & Liong, M.-T. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21134608 · Cited by 83 · see citing works

Roles for the gut microbiota in regulating neuronal feeding circuits

Yu, K. B., & Hsiao, E. Y. (2021) · Journal of Clinical Investigation · doi:10.1172/jci143772 · Cited by 81 · see citing works

Is the Impact of Starvation on the Gut Microbiota Specific or Unspecific to Anorexia Nervosa? A Narrative Review Based on a Systematic Literature Search

Mack, I., Penders, J., Cook, J., Dugmore, J., Mazurak, N., & Enck, P. (2018) · Current Neuropharmacology · doi:10.2174/1570159x16666180118101354 · Cited by 79 · see citing works

Glutamate interactions with obesity, insulin resistance, cognition and gut microbiota composition

Palomo-Buitrago, M. E., Sabater, M., Moreno‐Navarrete, J. M., Caballano‐Infantes, E., Arnoriaga‐Rodríguez, M., Coll, C., Ramió, L., Palomino‐Schätzlein, M., Gutiérrez-Carcedo, P., Pérez‐Brocal, V., et al. (2019) · Acta Diabetologica · doi:10.1007/s00592-019-01313-w · Cited by 76 · see citing works

Cordycepin reduces weight through regulating gut microbiota in high-fat diet-induced obese rats

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Large‐scale functional network connectivity mediate the associations of gut microbiota with sleep quality and executive functions

Cai, H., Wang, C., Qian, Y., Zhang, S., Zhang, C., Zhao, W., Zhang, T., Zhang, B., Chen, J., Liu, S., et al. (2021) · Human Brain Mapping · doi:10.1002/hbm.25419 · Cited by 74 · see citing works

Fecal Short-Chain Fatty Acid Ratios as Related to Gastrointestinal and Depressive Symptoms in Young Adults

Müller, B., Rasmusson, A. J., Just, D., Jayarathna, S., Moazzami, A. A., Novičić, Z. K., & Cunningham, J. L. (2021) · Psychosomatic Medicine · doi:10.1097/psy.0000000000000965 · Cited by 73 · see citing works

Gastrointestinal symptoms are predictive of trajectories of cognitive functioning in de novo Parkinson's disease

Jones, J. D., Rahmani, E., Garcia, E., & Jacobs, J. P. (2020) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2020.01.009 · Cited by 71 · see citing works

The Significance of Hypothalamic Inflammation and Gliosis for the Pathogenesis of Obesity in Humans

SEWAYBRICKER, L. E., Huang, A., Chandrasekaran, S., Melhorn, S. J., & Schur, E. A. (2022) · Endocrine Reviews · doi:10.1210/endrev/bnac023 · Cited by 73 · see citing works

Crosstalk Between the Gut Microbiota and the Brain: An Update on Neuroimaging Findings

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Early constipation predicts faster dementia onset in Parkinson’s disease

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Metformin Restores Hippocampal Neurogenesis and Learning and Memory via Regulating Gut Microbiota in the Obese Mouse Model

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Insular resting state functional connectivity is associated with gut microbiota diversity

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The Gut Microbiome–Brain Crosstalk in Neurodegenerative Diseases

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Gut Microbiome and Modulation of <scp>CNS</scp> Function

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The Gut Metagenome Changes in Parallel to Waist Circumference, Brain Iron Deposition, and Cognitive Function

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Innovative biomarkers in psychiatric disorders: a major clinical challenge in psychiatry

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Multimodal neuroimaging fusion biomarkers mediate the association between gut microbiota and cognition

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Spinal cord injury and gut microbiota: A review

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The Link between Gut Dysbiosis Caused by a High-Fat Diet and Hearing Loss

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Towards Tailored Gut Microbiome-Based and Dietary Interventions for Promoting the Development and Maintenance of a Healthy Brain

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Fecal Microbiota Transplantation Derived from Alzheimer’s Disease Mice Worsens Brain Trauma Outcomes in Wild-Type Controls

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Gut Microbiota and Microbiota-Related Metabolites as Possible Biomarkers of Cognitive Aging

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Biodiversity, the Human Microbiome and Mental Health: Moving toward a New Clinical Ecology for the 21st Century?

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Gut microbiome-gut brain axis-depression: interconnection

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Microbiome-gut-brain axis in brain development, cognition and behavior during infancy and early childhood

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Consumption of a fermented dairy beverage improves hippocampal-dependent relational memory in a randomized, controlled cross-over trial

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Effects of Oat Fiber Intervention on Cognitive Behavior in LDLR^–/– Mice Modeling Atherosclerosis by Targeting the Microbiome–Gut–Brain Axis

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Possible role of tryptophan metabolism along the microbiota-gut-brain axis on cognitive & behavioral aspects in Phenylketonuria

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Potential Beneficial Effects of Probiotics on Human Migraine Headache: A Literature Review

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Gut-brain axis and Alzheimer's disease: Therapeutic interventions and strategies

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The Interplay between Gut Microbiota and Cognitive Functioning in the Healthy Aging Population: A Systematic Review

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Unlocking the mind-gut connection: Impact of human microbiome on cognition

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Out of our skull, in our skin: the Microbiota-Gut-Brain axis and the Extended Cognition Thesis

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Dietary α-lactalbumin alters energy balance, gut microbiota composition and intestinal nutrient transporter expression in high-fat diet-fed mice

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Obesity and the Brain

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Gut microbiota from mice with cerebral ischemia-reperfusion injury affects the brain in healthy mice

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Depressive, anxiety and hypomanic symptoms in schizophrenia may be driven by tryptophan catabolite (TRYCAT) patterning of IgA and IgM responses directed to TRYCATs

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Gut dysbiosis as a driver of neuroinflammation in attention-deficit/hyperactivity disorder: A review of current evidence

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Gut-Brain Axis Deregulation and Its Possible Contribution to Neurodegenerative Disorders

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Gut microbes and behavior

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The Gut Brain-Axis in Neurological Diseases

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High-fidelity porcine models of metabolic syndrome: a contemporary synthesis

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The Brain–Gut Health Initiative (BIGHI): A Prospective Cohort on Psychiatric Disorders in China

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The Gut Metagenome Changes in Parallel to Waist Circumference, Brain Iron Deposition, and Cognitive Function

Blasco, G., Moreno‐Navarrete, J. M., Rivero, M., Pérez‐Brocal, V., Garre‐Olmo, J., Puig, J., Daunis‐i‐Estadella, P., Biarnés, C., Gich, J., Fernández‐Aranda, F., et al. (2017) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2017-00133 · Cited by 51 · see citing works

Cognitive function in obesity: interactions with the gut microbiome

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Obesity is associated with a distinct brain-gut microbiome signature that connects Prevotella and Bacteroides to the brain’s reward center

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Gut microbiome, cognitive function and brain structure: a multi-omics integration analysis

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Gut Microbiome, Inflammation, and Cerebrovascular Function: Link Between Obesity and Cognition

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