Networking in a global world: establishing functional connections between neural splicing regulators and their target transcripts

RNA-Seq: a revolutionary tool for transcriptomics

Wang, Z., Gerstein, M., & Snyder, M. (2009) · Nature Reviews Genetics · doi:10.1038/nrg2484 · Cited by 13,174 · see citing works

Cluster analysis and display of genome-wide expression patterns

Eisen, M. B., Spellman, P. T., Brown, P. O., & Botstein, D. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.25.14863 · Cited by 12,617 · see citing works

Quantitative Monitoring of Gene Expression Patterns with a Complementary DNA Microarray

Schena, M., Shalon, D., Davis, R. W., & Brown, P. O. (1995) · Science · doi:10.1126/science.270.5235.467 · Cited by 9,609 · see citing works

Genome-wide atlas of gene expression in the adult mouse brain

Lein, E. S., Hawrylycz, M. J., Ao, N., Ayres, M., Bensinger, A., Bernard, A., Boe, A. F., Boguski, M. S., Brockway, K. S., Byrnes, E. J., et al. (2007) · Nature · doi:10.1038/nature05453 · Cited by 5,572 · see citing works

Alternative isoform regulation in human tissue transcriptomes

Wang, E. T., Sandberg, R., Luo, S., Khrebtukova, I., Zhang, L., Mayr, C., Kingsmore, S. F., Schroth, G. P., & Burge, C. B. (2008) · Nature · doi:10.1038/nature07509 · Cited by 5,181 · see citing works

Exploring the metabolic and genetic control of gene expression on a genomic scale.

Derisi, J., Iyer, V., & Brown, P. (1997) · Science · doi:10.1126/science.278.5338.680 · Cited by 4,832 · see citing works

Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing

Pan, Q., Shai, O., Lee, L. J., Frey, B. J., & Blencowe, B. J. (2008) · Nature Genetics · doi:10.1038/ng.259 · Cited by 3,951 · see citing works

A gene atlas of the mouse and human protein-encoding transcriptomes

Su, A. I., Wiltshire, T., Batalov, S., Lapp, H., Ching, K. A., Block, D., Zhang, J., Soden, R., Hayakawa, M., Kreiman, G., et al. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0400782101 · Cited by 3,475 · see citing works

Transcriptome-wide Identification of RNA-Binding Protein and MicroRNA Target Sites by PAR-CLIP

Hafner, M., Landthaler, M., Burger, L., Khorshid, M., Hausser, J., Berninger, P., Rothballer, A., Ascano, M., Jungkamp, A.-C., Munschauer, M., et al. (2010) · Cell · doi:10.1016/j.cell.2010.03.009 · Cited by 2,873 · see citing works

The Nuclear-Retained Noncoding RNA MALAT1 Regulates Alternative Splicing by Modulating SR Splicing Factor Phosphorylation

Tripathi, V., Ellis, J. D., Shen, Z., Song, D. Y., Pan, Q., Watt, A. T., Freier, S. M., Bennett, C. F., Sharma, A., Bubulya, P. A., et al. (2010) · Molecular Cell · doi:10.1016/j.molcel.2010.08.011 · Cited by 2,223 · see citing works

Expansion of the eukaryotic proteome by alternative splicing

Nilsen, T. W., & Graveley, B. R. (2010) · Nature · doi:10.1038/nature08909 · Cited by 2,172 · see citing works

The Transcriptional Program of Sporulation in Budding Yeast

Chu, S., DeRisi, J. L., Eisen, M. B., Mulholland, J., Botstein, D., Brown, P. O., & Herskowitz, I. (1998) · Science · doi:10.1126/science.282.5389.699 · Cited by 1,860 · see citing works

The developmental transcriptome of Drosophila melanogaster

Graveley, B. R., Brooks, A. N., Carlson, J. W., Duff, M. O., Landolin, J. M., Yang, L. C., Artieri, C. G., van Baren, M. J., Boley, N. P., Booth, B. W., et al. (2010) · Nature · doi:10.1038/nature09715 · Cited by 1,487 · see citing works

Genome-Wide Survey of Human Alternative Pre-mRNA Splicing with Exon Junction Microarrays

Johnson, J. M., Castle, J. C., Garrett-Engele, P. W., Kan, Z., Loerch, P., Armour, C. D., Santos, R., Schadt, E. E., Stoughton, R. B., & Shoemaker, D. D. (2003) · Science · doi:10.1126/science.1090100 · Cited by 1,418 · see citing works

Mapping autism risk loci using genetic linkage and chromosomal rearrangements

The Autism Genome Project Consortium (2007) · Nature Genetics · doi:10.1038/ng1985 · Cited by 1,402 · see citing works

The MicroRNA miR-124 Promotes Neuronal Differentiation by Triggering Brain-Specific Alternative Pre-mRNA Splicing

Makeyev, E. V., Zhang, J., Carrasco, M. A., & Maniatis, T. (2007) · Molecular Cell · doi:10.1016/j.molcel.2007.07.015 · Cited by 1,395 · see citing works

HITS-CLIP yields genome-wide insights into brain alternative RNA processing

Licatalosi, D. D., Mele, A., Fak, J. J., Ule, J., Kayikci, M., Chi, S. W., Clark, T. A., Schweitzer, A. C., Blume, J. E., Wang, X., et al. (2008) · Nature · doi:10.1038/nature07488 · Cited by 1,352 · see citing works

RNA regulons: coordination of post-transcriptional events

Keene, J. D. (2007) · Nature Reviews Genetics · doi:10.1038/nrg2111 · Cited by 1,321 · see citing works

Mechanisms of alternative splicing regulation: insights from molecular and genomics approaches

Chen, M., & Manley, J. L. (2009) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2777 · Cited by 1,284 · see citing works

RNA and Disease

Cooper, T. A., Wan, L., & Dreyfuss, G. (2009) · Cell · doi:10.1016/j.cell.2009.02.011 · Cited by 1,160 · see citing works

An extensive network of coupling among gene expression machines

Maniatis, T., & Reed, R. (2002) · Nature · doi:10.1038/416499a · Cited by 1,148 · see citing works

iCLIP reveals the function of hnRNP particles in splicing at individual nucleotide resolution

König, J., Zarnack, K., Rot, G., Curk, T., Kayikci, M., Zupan, B., Turner, D. J., Luscombe, N. M., & Ule, J. (2010) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1838 · Cited by 1,126 · see citing works

The SR protein family of splicing factors: master regulators of gene expression

Long, J. C., & Cáceres, J. F. (2008) · Biochemical Journal · doi:10.1042/bj20081501 · Cited by 1,125 · see citing works

Alternative Splicing: New Insights from Global Analyses

Blencowe, B. J. (2006) · Cell · doi:10.1016/j.cell.2006.06.023 · Cited by 1,122 · see citing works

CLIP Identifies Nova-Regulated RNA Networks in the Brain

Ule, J., Jensen, K. B., Ruggiu, M., Mele, A., Ule, A., & Darnell, R. B. (2003) · Science · doi:10.1126/science.1090095 · Cited by 1,120 · see citing works

Regulation of Alternative Splicing by Histone Modifications

Luco, R. F., Pan, Q., Tominaga, K., Blencowe, B. J., Pereira‐Smith, O. M., & Misteli, T. (2010) · Science · doi:10.1126/science.1184208 · Cited by 1,099 · see citing works

Alternative splicing and evolution: diversification, exon definition and function

Keren, H., Lev-Maor, G., & Ast, G. (2010) · Nature Reviews Genetics · doi:10.1038/nrg2776 · Cited by 1,082 · see citing works

Predictive Identification of Exonic Splicing Enhancers in Human Genes

Fairbrother, W. G., Yeh, R., Sharp, P. A., & Burge, C. B. (2002) · Science · doi:10.1126/science.1073774 · Cited by 1,019 · see citing works

Integrative Analysis of the Caenorhabditis elegans Genome by the modENCODE Project

Gerstein, M., Lu, Z. J., Nostrand, E. L. V., Cheng, C., Arshinoff, B. I., Liu, T., Yip, K. Y.-L., Robilotto, R., Rechtsteiner, A., Ikegami, K., et al. (2010) · Science · doi:10.1126/science.1196914 · Cited by 959 · see citing works

Comprehensive proteomic analysis of the human spliceosome

Zhou, Z., Licklider, L. J., Gygi, S. P., & Reed, R. (2002) · Nature · doi:10.1038/nature01031 · Cited by 893 · see citing works

Deciphering the splicing code

Barash, Y., Calarco, J. A., Gao, W., Pan, Q., Wang, X., Ofer Shai, A., Blencowe, B. J., & Frey, B. J. (2010) · Nature · doi:10.1038/nature09000 · Cited by 891 · see citing works

Pre-mRNA Processing Reaches Back toTranscription and Ahead to Translation

Moore, M. J., & Proudfoot, N. J. (2009) · Cell · doi:10.1016/j.cell.2009.02.001 · Cited by 835 · see citing works

SR proteins: a conserved family of pre-mRNA splicing factors.Preprint

Zahler, A. M., Lane, W. S., Stolk, J. A., & Roth, M. (1992) · Genes & Development · doi:10.1101/gad.6.5.837 · Cited by 798 · see citing works

RNA processing and its regulation: global insights into biological networks

Licatalosi, D. D., & Darnell, R. B. (2009) · Nature Reviews Genetics · doi:10.1038/nrg2673 · Cited by 760 · see citing works

Specific interactions between proteins implicated in splice site selection and regulated alternative splicing

Wu, J. Y., & Maniatis, T. (1993) · Cell · doi:10.1016/0092-8674(93)90316-i · Cited by 755 · see citing works

High-Throughput Mapping of a Dynamic Signaling Network in Mammalian Cells

Barrios‐Rodiles, M., Brown, K. R., Ozdamar, B., Bose, R., Liu, Z., Donovan, R. S., Shinjo, F., Liu, Y., Dembowy, J., Taylor, I. W., et al. (2005) · Science · doi:10.1126/science.1105776 · Cited by 726 · see citing works

Exonic splicing enhancers: mechanism of action, diversity and role in human genetic diseases

Blencowe, B. J. (2000) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(00)01549-8 · Cited by 698 · see citing works

Systematic Identification and Analysis of Exonic Splicing Silencers

Wang, Z., Rolish, M. E., Yeo, G. W.-M., Tung, V., Mawson, M., & Burge, C. B. (2004) · Cell · doi:10.1016/j.cell.2004.11.010 · Cited by 694 · see citing works

Unproductive splicing of SR genes associated with highly conserved and ultraconserved DNA elements

Lareau, L. F., Inada, M., Green, R. E., Wengrod, J., & Brenner, S. E. (2007) · Nature · doi:10.1038/nature05676 · Cited by 685 · see citing works

Differential chromatin marking of introns and expressed exons by H3K36me3

Kolasinska-Zwierz, P., Down, T. A., Latorre, I. J., Liu, T., Liu, X. S., & Ahringer, J. (2009) · Nature Genetics · doi:10.1038/ng.322 · Cited by 671 · see citing works

Chromatin organization marks exon-intron structure

Schwartz, S., Meshorer, E., & Ast, G. (2009) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1659 · Cited by 638 · see citing works

Yeast Two-Hybrid, a Powerful Tool for Systems Biology

Brückner, A., Polge, C., Lentze, N., Auerbach, D., & Schlattner, U. (2009) · International Journal of Molecular Sciences · doi:10.3390/ijms10062763 · Cited by 618 · see citing works

RIP-Chip: the isolation and identification of mRNAs, microRNAs and protein components of ribonucleoprotein complexes from cell extracts

Keene, J. D., Komisarow, J. M., & Friedersdorf, M. B. (2006) · Nature Protocols · doi:10.1038/nprot.2006.47 · Cited by 612 · see citing works

SMN Deficiency Causes Tissue-Specific Perturbations in the Repertoire of snRNAs and Widespread Defects in Splicing

Zhang, Z., Lotti, F., Dittmar, K. A., Younis, I., Wan, L., Kasim, M., & Dreyfuss, G. (2008) · Cell · doi:10.1016/j.cell.2008.03.031 · Cited by 610 · see citing works

Diverse molecular functions of Hu proteins

Hinman, M. N., & Lou, H. (2008) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-008-8252-6 · Cited by 587 · see citing works

A post-transcriptional regulatory switch in polypyrimidine tract-binding proteins reprograms alternative splicing in developing neurons

Boutz, P. L., Stoilov, P., Li, Q., Lin, C.-H., Chawla, G., Ostrow, K., Shiue, L., Ares, M., & Black, D. L. (2007) · Genes & Development · doi:10.1101/gad.1558107 · Cited by 577 · see citing works

An RNA code for the FOX2 splicing regulator revealed by mapping RNA-protein interactions in stem cells

Yeo, G. W., Coufal, N. G., Liang, T. Y., Peng, G. E., Fu, X.-D., & Gage, F. H. (2009) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1545 · Cited by 572 · see citing works

ESRP1 and ESRP2 Are Epithelial Cell-Type-Specific Regulators of FGFR2 Splicing

Warzecha, C. C., Sato, T. K., Nabet, B., Hogenesch, J. B., & Carstens, R. P. (2009) · Molecular Cell · doi:10.1016/j.molcel.2009.01.025 · Cited by 570 · see citing works

Computation for ChIP-seq and RNA-seq studies

Pepke, S., Wold, B. J., & Mortazavi, A. (2009) · Nature Methods · doi:10.1038/nmeth.1371 · Cited by 553 · see citing works

HuD, a paraneoplastic encephalomyelitis antigen, contains RNA-binding domains and is homologous to Elav and sex-lethal

Szabo, A., Dalmau, J., Manley, G., Rosenfeld, M., Wong, E., Henson, J., Posner, J. B., & Furneaux, H. M. (1991) · Cell · doi:10.1016/0092-8674(91)90184-z · Cited by 553 · see citing works

Ultraconserved elements are associated with homeostatic control of splicing regulators by alternative splicing and nonsense-mediated decayPreprint

Ni, J. Z., Grate, L. R., Donohue, J. P., Preston, C. G., Nobida, N., O’Brien, G. S., Shiue, L., Clark, T. A., Blume, J. E., & Ares, M. (2007) · Genes & Development · doi:10.1101/gad.1525507 · Cited by 551 · see citing works

An RNA map predicting Nova-dependent splicing regulation

Ule, J., Stefani, G., Mele, A., Ruggiu, M., Wang, X., Taneri, B., Gaasterland, T., Blencowe, B. J., & Darnell, R. B. (2006) · Nature · doi:10.1038/nature05304 · Cited by 528 · see citing works

Nova regulates brain-specific splicing to shape the synapse

Ule, J., Ule, A., Spencer, J., Williams, A., Hu, J.-S., Cline, M., Wang, H., Clark, T., Fraser, C., Ruggiu, M., et al. (2005) · Nature Genetics · doi:10.1038/ng1610 · Cited by 509 · see citing works

A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart

Kalsotra, A., Xiao, X., Ward, A. J., Castle, J. C., Johnson, J. M., Burge, C. B., & Cooper, T. A. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0809045105 · Cited by 508 · see citing works

Modulation of synaptic plasticity and memory by Reelin involves differential splicing of the lipoprotein receptor Apoer2

Beffert, U., Weeber, E. J., Durudas, A., Qiu, S., Masiulis, I., Sweatt, J. D., Li, W.-P., Adelmann, G., Frotscher, M., Hammer, R. E., et al. (2005) · Neuron · doi:10.1016/j.neuron.2005.07.007 · Cited by 497 · see citing works

A protein factor, ASF, controls cell-specific alternative splicing of SV40 early pre-mRNA in vitro

Ge, H., & Manley, J. L. (1990) · Cell · doi:10.1016/0092-8674(90)90236-8 · Cited by 494 · see citing works

Muscleblind proteins regulate alternative splicing

Ho, T. H., Charlet‐Berguerand, N., Poulos, M. G., Singh, G., Swanson, M. S., & Cooper, T. A. (2004) · The EMBO Journal · doi:10.1038/sj.emboj.7600300 · Cited by 494 · see citing works

fruitless Splicing Specifies Male Courtship Behavior in Drosophila

Demir, E., & Dickson, B. J. (2005) · Cell · doi:10.1016/j.cell.2005.04.027 · Cited by 493 · see citing works

The human SWI/SNF subunit Brm is a regulator of alternative splicing

Batsché, E., Yaniv, M., & Muchardt, C. (2006) · Nature Structural & Molecular Biology · doi:10.1038/nsmb1030 · Cited by 471 · see citing works

Genome-wide Analysis of PTB-RNA Interactions Reveals a Strategy Used by the General Splicing Repressor to Modulate Exon Inclusion or Skipping

Xue, Y., Zhou, Y., Wu, T., Zhu, T., Ji, X., Kwon, Y.-S., Zhang, C., Yeo, G., Black, D. L., Sun, H., et al. (2009) · Molecular Cell · doi:10.1016/j.molcel.2009.12.003 · Cited by 469 · see citing works

The essential pre-mRNA splicing factor SF2 influences 5′ splice site selection by activating proximal sites

Krainer, A. R., Conway, G. C., & Kozak, D. (1990) · Cell · doi:10.1016/0092-8674(90)90237-9 · Cited by 461 · see citing works

Signal-dependent regulation of splicing via phosphorylation of Sam68

Matter, N., Herrlich, P., & König, H. (2002) · Nature · doi:10.1038/nature01153 · Cited by 458 · see citing works

The CELF Family of RNA Binding Proteins Is Implicated in Cell-Specific and Developmentally Regulated Alternative Splicing

Ladd, A. N., Charlet‐Berguerand, N., & Cooper, T. A. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.4.1285-1296.2001 · Cited by 449 · see citing works

Nucleosome positioning as a determinant of exon recognition

Tilgner, H., Nikolaou, C., Althammer, S., Sammeth, M., Beato, M., Valcárcel, J., & Guigó, R. (2009) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1658 · Cited by 446 · see citing works

Spatial and Temporal Expression of the Zebrafish Genome by Large-Scale In Situ Hybridization Screening

Thisse, B., Heyer, V., Lux, A., Alunni, V., Degrave, A., Seiliez, I., Kirchner, J., Parkhill, J.-P., & Thisse, C. (2004) · Methods in cell biology · doi:10.1016/s0091-679x(04)77027-2 · Cited by 436 · see citing works

An RNA-binding protein associated with Src through its SH2 and SH3 domains in mitosis

Taylor, S. J., & Shalloway, D. I. (1994) · Nature · doi:10.1038/368867a0 · Cited by 426 · see citing works

Nova-1 Regulates Neuron-Specific Alternative Splicing and Is Essential for Neuronal Viability

Jensen, K. B., Dredge, B. K., Stefani, G., Zhong, R., Buckanovich, R. J., Okano, H. J., Yang, Y. Y. L., & Darnell, R. B. (2000) · Neuron · doi:10.1016/s0896-6273(00)80900-9 · Cited by 426 · see citing works

Computational definition of sequence motifs governing constitutive exon splicingPreprint

Zhang, X. H.-F., & Chasin, L. A. (2004) · Genes & Development · doi:10.1101/gad.1195304 · Cited by 420 · see citing works

Genomewide Analysis of mRNA Processing in Yeast Using Splicing-Specific Microarrays

Clark, T. A., Sugnet, C. W., & Ares, M. (2002) · Science · doi:10.1126/science.1069415 · Cited by 411 · see citing works

Reversible cross-linking combined with immunoprecipitation to study RNA–protein interactions in vivo

Niranjanakumari, S. (2002) · Methods · doi:10.1016/s1046-2023(02)00021-x · Cited by 410 · see citing works

Cracking the RNA polymerase II CTD code

Egloff, S., & Murphy, S. (2008) · Trends in Genetics · doi:10.1016/j.tig.2008.03.008 · Cited by 408 · see citing works

Identification of Neuronal Nuclei (NeuN) as Fox-3, a New Member of the Fox-1 Gene Family of Splicing Factors

Kim, K. K., Adelstein, R. S., & Kawamoto, S. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.052969 · Cited by 398 · see citing works

Identifying mRNA subsets in messenger ribonucleoprotein complexes by using cDNA arrays

Tenenbaum, S. A., Carson, C. C., Lager, P. J., & Keene, J. D. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.26.14085 · Cited by 397 · see citing works

Biased chromatin signatures around polyadenylation sites and exons

Nielsen, C. B., Padgett, R. A., Spies, N., & Burge, C. B. (2009) · DSpace@MIT (Massachusetts Institute of Technology) · Cited by 390 · see citing works

An ESRP‐regulated splicing programme is abrogated during the epithelial–mesenchymal transition

Warzecha, C. C., Jiang, P., Amirikian, K., Dittmar, K. A., Lu, H., Shen, S., Guo, W., Xing, Y., & Carstens, R. P. (2010) · The EMBO Journal · doi:10.1038/emboj.2010.195 · Cited by 383 · see citing works

Neuronal regulation of alternative pre-mRNA splicing

Li, Q., Lee, J.-A., & Black, D. L. (2007) · Nature Reviews Neuroscience · doi:10.1038/nrn2237 · Cited by 376 · see citing works

Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis

Jurica, M. S., Licklider, L. J., Gygi, S. P., Grigorieff, N., & Moore, M. J. (2002) · RNA · doi:10.1017/s1355838202021088 · Cited by 370 · see citing works

Evidence for reassociation of RNA-binding proteins after cell lysis: Implications for the interpretation of immunoprecipitation analyses

Mili, S., & STEITZ, J. A. (2004) · RNA · doi:10.1261/rna.7151404 · Cited by 369 · see citing works

A target for Src in mitosis

Fumagalli, S., Totty, N. F., Hsuan, J. J., & Courtneidge, S. A. (1994) · Nature · doi:10.1038/368871a0 · Cited by 365 · see citing works

Cancer-associated regulation of alternative splicing

Venables, J. P., Klinck, R., Koh, C., Gervais-Bird, J., Bramard, A., Inkel, L., Durand, M., Couture, S., Froehlich, U., Lapointe, E., et al. (2009) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1608 · Cited by 340 · see citing works

The quaking gene product necessary in embryogenesis and myelination combines features of RNA binding and signal transduction proteins

Ebersole, T. A., Chen, Q., Justice, M. J., & Artzt, K. (1996) · Nature Genetics · doi:10.1038/ng0396-260 · Cited by 340 · see citing works

The RNA-binding protein Sam68 modulates the alternative splicing of Bcl-x

Paronetto, M. P., Achsel, T., Massiello, A., Chalfant, C. E., & Sette, C. (2007) · The Journal of Cell Biology · doi:10.1083/jcb.200701005 · Cited by 334 · see citing works

Regulated tissue-specific expression of antagonistic pre-mRNA splicing factors.

Hanamura, A., Cáceres, J. F., Mayeda, A., Franza, B. R., & Krainer, A. R. (1998) · PubMed Central · Cited by 329 · see citing works

Revealing global regulatory features of mammalian alternative splicing using a quantitative microarray platform

Pan, Q., Shai, O., Misquitta, C., Zhang, W., Saltzman, A. L., Mohammad, N., Babak, T., Siu, H., Hughes, T. R., Morris, Q. D., et al. (2004) · Molecular Cell · doi:10.1016/j.molcel.2004.12.004 · Cited by 323 · see citing works

Expression of 24,426 human alternative splicing events and predicted cis regulation in 48 tissues and cell lines

Castle, J. C., Zhang, C., Shah, J. K., Kulkarni, A., Kalsotra, A., Cooper, T. A., & Johnson, J. M. (2008) · Nature Genetics · doi:10.1038/ng.264 · Cited by 319 · see citing works

Sequence-Specific RNA Binding by a Nova KH Domain

Lewis, H. A., Musunuru, K., Jensen, K. B., Edo, C., Chen, H., Darnell, R. B., & Burley, S. K. (2000) · Cell · doi:10.1016/s0092-8674(00)80668-6 · Cited by 319 · see citing works

Nova, the paraneoplastic Ri antigen, is homologous to an RNA-binding protein and is specifically expressed in the developing motor system

Buckanovich, R. J., Posner, J. B., & Darnell, R. B. (1993) · Neuron · doi:10.1016/0896-6273(93)90077-5 · Cited by 318 · see citing works

An Alternative Splicing Network Links Cell-Cycle Control to Apoptosis

Moore, M. J., Wang, Q., Kennedy, C. J., & Silver, P. A. (2010) · Cell · doi:10.1016/j.cell.2010.07.019 · Cited by 316 · see citing works

Crossregulation and Functional Redundancy between the Splicing Regulator PTB and Its Paralogs nPTB and ROD1

Spellman, R., Llorian, M., & Smith, C. W. J. (2007) · Molecular Cell · doi:10.1016/j.molcel.2007.06.016 · Cited by 313 · see citing works

The functional landscape of mouse gene expression

Zhang, W., Morris, Q., Chang, R., Shai, O., Bakowski, M. A., Mitsakakis, N., Mohammad, N., Robinson, M. D., Zirngibl, R. A., Somogyi, E., et al. (2004) · Journal of Biology · doi:10.1186/jbiol16 · Cited by 312 · see citing works

Cooperative Assembly of an hnRNP Complex Induced by a Tissue-Specific Homolog of Polypyrimidine Tract Binding Protein

Markovtsov, V. V., Nikolic, J. M., Goldman, J. A., Turck, C. W., Chou, M., & Black, D. L. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.20.7463-7479.2000 · Cited by 311 · see citing works

A vertebrate RNA-binding protein Fox-1 regulates tissue-specific splicing via the pentanucleotide GCAUG

Jin, Y., Suzuki, H., Maegawa, S., Endo, H., Sugano, S., Hashimoto, K., Yasuda, K., & Inoue, K. (2003) · The EMBO Journal · doi:10.1093/emboj/cdg089 · Cited by 311 · see citing works

DNA Damage Regulates Alternative Splicing through Inhibition of RNA Polymerase II Elongation

Muñoz, M. J., Perez-Santángelo, S., Paronetto, M. P., de la Mata, M., Pelisch, F., Boireau, S., Glover-Cutter, K. M., Ben-Dov, C., Blaustein, M., Lozano, J. J., et al. (2009) · Cell · doi:10.1016/j.cell.2009.03.010 · Cited by 310 · see citing works

MicroRNAs regulate the expression of the alternative splicing factor nPTB during muscle development

Boutz, P. L., Chawla, G., Stoilov, P., & Black, D. L. (2007) · Genes & Development · doi:10.1101/gad.1500707 · Cited by 304 · see citing works

Protein composition of human prespliceosomes isolated by a tobramycin affinity-selection method

Hartmuth, K., Urlaub, H., Vornlocher, H., Will, C. L., Gentzel, M., Wilm, M. S., & Lührmann, R. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.262483899 · Cited by 302 · see citing works

STAR, a gene family involved in signal transduction and activation of RNA

Vernet, C., & Artzt, K. (1997) · Trends in Genetics · doi:10.1016/s0168-9525(97)01269-9 · Cited by 301 · see citing works

Defining the regulatory network of the tissue-specific splicing factors Fox-1 and Fox-2

Zhang, C., Zhang, Z., Castle, J., Sun, S., Johnson, J., Krainer, A. R., & Zhang, M. Q. (2008) · Genes & Development · doi:10.1101/gad.1703108 · Cited by 300 · see citing works

Integrative Modeling Defines the Nova Splicing-Regulatory Network and Its Combinatorial Controls

Zhang, C., Frias, M. A., Mele, A., Ruggiu, M., Eom, T., Marney, C. B., Wang, H., Licatalosi, D. D., Fak, J. J., & Darnell, R. B. (2010) · Science · doi:10.1126/science.1191150 · Cited by 294 · see citing works

Identification of alternative splicing regulators by RNA interference in Drosophila

Park, J. W., Parisky, K. M., Celotto, A. M., Reenan, R. A., & Graveley, B. R. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0407004101 · Cited by 290 · see citing works

A Gene Expression Map for the Euchromatic Genome of Drosophila melanogaster

Štolc, V., Gauhar, Z., Mason, C. E., Halasz, G., van Batenburg, M. F., Rifkin, S. A., Hua, S., Herreman, T., Tongprasit, W., Barbano, P. E., et al. (2004) · Science · doi:10.1126/science.1101312 · Cited by 290 · see citing works

The sex-determining gene tra-2 of Drosophila encodes a putative RNA binding protein

Amrein, H., Gorman, M., & Nöthiger, R. (1988) · Cell · doi:10.1016/0092-8674(88)90247-4 · Cited by 279 · see citing works

Homologues of the <i>Caenorhabditis elegans</i> Fox-1 Protein Are Neuronal Splicing Regulators in Mammals

Underwood, J. G., Boutz, P. L., Dougherty, J. D., Stoilov, P., & Black, D. L. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.22.10005-10016.2005 · Cited by 272 · see citing works

Position-dependent alternative splicing activity revealed by global profiling of alternative splicing events regulated by PTB

Llorian, M., Schwartz, S., Clark, T. A., Hollander, D., Tan, L.-Y., Spellman, R., Gordon, A., Schweitzer, A. C., de la Grange, P., Ast, G., et al. (2010) · Nature Structural &amp; Molecular Biology · doi:10.1038/nsmb.1881 · Cited by 263 · see citing works

Visualization of image data from cells to organisms

Walter, T., Shattuck, D. W., Baldock, R., Bastin, M. E., Carpenter, A. E., Duce, S., Ellenberg, J., Fraser, A. N., Hamilton, N., Pieper, S., et al. (2010) · Nature Methods · doi:10.1038/nmeth.1431 · Cited by 261 · see citing works

Alternative splicing and RNA selection pressure — evolutionary consequences for eukaryotic genomes

Xing, Y., & Lee, C. J. (2006) · Nature Reviews Genetics · doi:10.1038/nrg1896 · Cited by 259 · see citing works

The Neuronal RNA Binding Protein Nova-1 Recognizes Specific RNA Targets In Vitro and In Vivo

Buckanovich, R. J., & Darnell, R. B. (1997) · Molecular and Cellular Biology · doi:10.1128/mcb.17.6.3194 · Cited by 259 · see citing works

The Coupling of Alternative Splicing and Nonsense-Mediated mRNA Decay

Lareau, L. F., Brooks, A. N., Soergel, D. A. W., Qi, M., & Brenner, S. E. (2007) · Advances in experimental medicine and biology · doi:10.1007/978-0-387-77374-2_12 · Cited by 253 · see citing works

The Muscleblind family of proteins: an emerging class of regulators of developmentally programmed alternative splicing

Pascual, M., Vicente-Crespo, M., Monferrer, L., & Artero, R. D. (2006) · Differentiation · doi:10.1111/j.1432-0436.2006.00060.x · Cited by 246 · see citing works

Sam68, the KH domain-containing superSTAR

Lukong, K. E., & Richard, S. (2003) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2003.09.001 · Cited by 240 · see citing works

Global impact of RNA polymerase II elongation inhibition on alternative splicing regulationPreprint

Ip, J. Y. Y., Schmidt, D., Pan, Q., Ramani, A. K., Fraser, A. G., Odom, D. T., & Blencowe, B. J. (2010) · Genome Research · doi:10.1101/gr.111070.110 · Cited by 237 · see citing works

Gene-specific RNA polymerase II phosphorylation and the CTD code

Kim, H., Erickson, B., Luo, W., Seward, D. J., Graber, J. H., Pollock, D. D., Megee, P. C., & Bentley, D. L. (2010) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1913 · Cited by 235 · see citing works

A brain-enriched polypyrimidine tract-binding protein antagonizes the ability of Nova to regulate neuron-specific alternative splicing

Polydorides, A. D., Okano, H. J., Yang, Y. Y. L., Stefani, G., & Darnell, R. B. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.110128397 · Cited by 230 · see citing works

Variation in sequence and organization of splicing regulatory elements in vertebrate genes

Yeo, G. W.-M., Hoon, S. S., Venkatesh, B., & Burge, C. B. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0404901101 · Cited by 226 · see citing works

Regulation of vertebrate nervous system alternative splicing and development by an SR-related protein

Calarco, J. A., Superina, S., O'Hanlon, D., Gabut, M., Raj, B., Pan, Q., Skalska, U., Clarke, L., Gelinas, D., van der Kooy, D., et al. (2009) · Cell · doi:10.1016/j.cell.2009.06.012 · Cited by 225 · see citing works

The RNA-binding protein HuD regulates neuronal cell identity and maturation

Akamatsu, W., Fujihara, H., Mitsuhashi, T., Yano, M., Shibata, S., Hayakawa, Y., Okano, H. J., Sakakibara, S.-I., Takano, H., Takano, T., et al. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0407523102 · Cited by 222 · see citing works

A neuron-specific splicing switch mediated by an array of pre-mRNA repressor sites: evidence of a regulatory role for the polypyrimidine tract binding protein and a brain-specific PTB counterpart.

Ashiya, M., & Grabowski, P. J. (1997) · PubMed · Cited by 220 · see citing works

The neuronal RNA-binding protein Nova-2 is implicated as the autoantigen targeted in POMA patients with dementia

Yang, Y. Y. L., Yin, G. L., & Darnell, R. B. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.22.13254 · Cited by 219 · see citing works

SR Proteins and Related Factors in Alternative Splicing

Lin, S., & Fu, X. (2007) · Advances in experimental medicine and biology · doi:10.1007/978-0-387-77374-2_7 · Cited by 214 · see citing works

Human QKI, a potential regulator of mRNA expression of human oligodendrocyte-related genes involved in schizophrenia

Åberg, K., Saetre, P., Jareborg, N., & Jazin, E. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0601213103 · Cited by 208 · see citing works

Regulation of alternative splicing by the core spliceosomal machineryPreprint

Saltzman, A. L., Pan, Q., & Blencowe, B. J. (2011) · Genes & Development · doi:10.1101/gad.2004811 · Cited by 204 · see citing works

Regulation of Multiple Core Spliceosomal Proteins by Alternative Splicing-Coupled Nonsense-Mediated mRNA Decay

Saltzman, A. L., Kim, Y. K., Pan, Q., Fagnani, M. M., Maquat, L. E., & Blencowe, B. J. (2008) · Molecular and Cellular Biology · doi:10.1128/mcb.00361-08 · Cited by 204 · see citing works

Transcript Specificity in Yeast Pre-mRNA Splicing Revealed by Mutations in Core Spliceosomal Components

Pleiss, J. A., Whitworth, G. B., Bergkessel, M., & Guthrie, C. (2007) · PLoS Biology · doi:10.1371/journal.pbio.0050090 · Cited by 199 · see citing works

A Pathway of Sequential Arginine-Serine-Rich Domain-Splicing Signal Interactions during Mammalian Spliceosome Assembly

Shen, H., & Green, M. R. (2004) · Molecular Cell · doi:10.1016/j.molcel.2004.10.021 · Cited by 199 · see citing works

Function of quaking in myelination: Regulation of alternative splicing

Wu, J. I., Reed, R., Grabowski, P. J., & Artzt, K. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.072090399 · Cited by 198 · see citing works

Unusual Intron Conservation near Tissue-Regulated Exons Found by Splicing Microarrays

Sugnet, C. W., Srinivasan, K., Clark, T. A., O’Brien, G. S., Cline, M., Wang, H., Williams, A., Kulp, D., Blume, J. E., Haussler, D. H., et al. (2006) · PLoS Computational Biology · doi:10.1371/journal.pcbi.0020004 · Cited by 194 · see citing works

Dynamic Antagonism between ETR-3 and PTB Regulates Cell Type-Specific Alternative Splicing

Charlet‐Berguerand, N., Singh, G., Cooper, T. A., & Logan, P. (2002) · Molecular Cell · doi:10.1016/s1097-2765(02)00479-3 · Cited by 190 · see citing works

Tissue-dependent isoforms of mammalian Fox-1 homologs are associated with tissue-specific splicing activities

Nakahata, S. (2005) · Nucleic Acids Research · doi:10.1093/nar/gki338 · Cited by 184 · see citing works

Polypyrimidine tract binding protein controls the transition from exon definition to an intron defined spliceosome

Sharma, S., Kohlstaedt, L. A., Damianov, A., Rio, D. C., & Black, D. L. (2008) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1375 · Cited by 177 · see citing works

Nova2 Regulates Neuronal Migration through an RNA Switch in Disabled-1 Signaling

Yano, M., Hayakawa-Yano, Y., Mele, A., & Darnell, R. B. (2010) · Neuron · doi:10.1016/j.neuron.2010.05.007 · Cited by 176 · see citing works

Functional integration of transcriptional and RNA processing machineries

Pandit, S., Wang, D., & Fu, X. (2008) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2008.03.001 · Cited by 173 · see citing works

Genome-wide analysis of alternative splicing in Caenorhabditis elegansPreprint

Ramani, A. K., Calarco, J. A., Pan, Q., Mavandadi, S., Wang, Y., Nelson, A. C., Lee, L. J., Morris, Q., Blencowe, B. J., Zhen, M., et al. (2010) · Genome Research · doi:10.1101/gr.114645.110 · Cited by 170 · see citing works

Current-generation high-throughput sequencing: deepening insights into mammalian transcriptomes

Blencowe, B. J., Ahmad, S., & Lee, L. J. (2009) · Genes &amp; Development · doi:10.1101/gad.1788009 · Cited by 168 · see citing works

A genome-wide in situhybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain

McKee, A. E., Minet, E., Stern, C., Riahi, S., Stiles, C. D., & Silver, P. A. (2005) · BMC Developmental Biology · doi:10.1186/1471-213x-5-14 · Cited by 166 · see citing works

Polypyrimidine Tract Binding Protein Blocks the 5′ Splice Site-Dependent Assembly of U2AF and the Prespliceosomal E Complex

Sharma, S., Falick, A. M., & Black, D. L. (2005) · Molecular Cell · doi:10.1016/j.molcel.2005.07.014 · Cited by 165 · see citing works

The sex determination locus transformer-2 of Drosophila encodes a polypeptide with similarity to RNA binding proteins

Goralski, T. J., Edström, J., & Baker, B. S. (1989) · Cell · doi:10.1016/0092-8674(89)90634-x · Cited by 159 · see citing works

Discovery and Analysis of Evolutionarily Conserved Intronic Splicing Regulatory Elements

Yeo, G. W.-M., Nostrand, E. L. V., & Liang, T. Y. (2007) · PLoS Genetics · doi:10.1371/journal.pgen.0030085 · Cited by 158 · see citing works

An inducible change in Fox-1/A2BP1 splicing modulates the alternative splicing of downstream neuronal target exonsPreprint

Lee, J.-A., Tang, Z., & Black, D. L. (2009) · Genes & Development · doi:10.1101/gad.1837009 · Cited by 158 · see citing works

Mammalian CELF/Bruno-like RNA-binding proteins: molecular characteristics and biological functions

Barreau, C., Paillard, L., Méreau, A., & Osborne, H. B. (2005) · Biochimie · doi:10.1016/j.biochi.2005.10.011 · Cited by 156 · see citing works

Global regulation of alternative splicing during myogenic differentiation

Bland, C. S., Wang, E. T., Vu, A. Q., David, M. P., Castle, J. C., Johnson, J. M., Burge, C. B., & Cooper, T. A. (2010) · Nucleic Acids Research · doi:10.1093/nar/gkq614 · Cited by 153 · see citing works

Genome-wide Analysis of Alternative Pre-mRNA Splicing

Ben-Dov, C., Hartmann, B., Lundgren, J., & Valcárcel, J. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.r700033200 · Cited by 151 · see citing works

Chemical-genomic dissection of the CTD code

Tietjen, J. R., Zhang, D. W., Rodríguez‐Molina, J. B., White, B. E., Akhtar, M. S., Heidemann, M., Li, X., Chapman, R. D., Shokat, K. M., Keleş, S., et al. (2010) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1900 · Cited by 148 · see citing works

The de novo chromosome 16 translocations of two patients with abnormal phenotypes (mental retardation and epilepsy) disrupt the A2BP1 gene

Bhalla, K., Phillips, H. A., Crawford, J., McKenzie, O. L. D., Mulley, J. C., Eyre, H., Gardner, A. E., Kremmidiotis, G., & Callen, D. F. (2004) · Journal of Human Genetics · doi:10.1007/s10038-004-0145-4 · Cited by 146 · see citing works

Neuronal proteins custom designed by alternative splicing

Lipscombe, D. (2005) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2005.04.002 · Cited by 145 · see citing works

CLIP: Crosslinking and ImmunoPrecipitation of In Vivo RNA Targets of RNA-Binding Proteins

Jensen, K. B., & Darnell, R. B. (2008) · Methods in molecular biology · doi:10.1007/978-1-60327-475-3_6 · Cited by 143 · see citing works

The carboxy terminal domain of RNA polymerase II and alternative splicing

Muñoz, M. J., de la Mata, M., & Kornblihtt, A. R. (2010) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2010.03.010 · Cited by 143 · see citing works

A high-throughput screening strategy identifies cardiotonic steroids as alternative splicing modulators

Stoilov, P., Lin, C.-H., Damoiseaux, R. D., Nikolic, J. M., & Black, D. L. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0801661105 · Cited by 141 · see citing works

The splicing regulator Sam68 binds to a novel exonic splicing silencer and functions in SMN2 alternative splicing in spinal muscular atrophy

Pedrotti, S., Bielli, P., Paronetto, M. P., Ciccosanti, F., Fimia, G. M., Stamm, S., Manley, J. L., & Sette, C. (2010) · The EMBO Journal · doi:10.1038/emboj.2010.19 · Cited by 135 · see citing works

Unbiased RNA–protein interaction screen by quantitative proteomics

Butter, F., Scheibe, M., Mörl, M., & Mann, M. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0812099106 · Cited by 134 · see citing works

Sam68 regulates translation of target mRNAs in male germ cells, necessary for mouse spermatogenesis

Paronetto, M. P., Messina, V., Bianchi, E., Barchi, M., Vogel, G., Moretti, C., Palombi, F., Stefanini, M., Geremia, R., Richard, S., et al. (2009) · The Journal of Cell Biology · doi:10.1083/jcb.200811138 · Cited by 133 · see citing works

Dynamic balance between activation and repression regulates pre‐mRNA alternative splicing during heart development

Ladd, A. N., Stenberg, M. G., Swanson, M. S., & Cooper, T. A. (2005) · Developmental Dynamics · doi:10.1002/dvdy.20382 · Cited by 131 · see citing works

Rapid-Response Splicing Reporter Screens Identify Differential Regulators of Constitutive and Alternative Splicing

Younis, I., Berg, M. G., Kaida, D., Dittmar, K. A., Wang, C., & Dreyfuss, G. (2010) · Molecular and Cellular Biology · doi:10.1128/mcb.01301-09 · Cited by 130 · see citing works

Dynamic Regulation of Alternative Splicing by Silencers that Modulate 5′ Splice Site Competition

Yu, Y., Maroney, P. A., Denker, J. A., Zhang, X. H.-F., Dybkov, O., Lührmann, R., Jankowsky, E., Chasin, L. A., & Nilsen, T. W. (2008) · Cell · doi:10.1016/j.cell.2008.10.046 · Cited by 129 · see citing works

MicroRNAs coordinate an alternative splicing network during mouse postnatal heart development

Kalsotra, A., Wang, K., Li, P.-F., & Cooper, T. A. (2010) · Genes &amp; Development · doi:10.1101/gad.1894310 · Cited by 129 · see citing works

Reciprocal intronic and exonic histone modification regions in humans

Huff, J. T., Plocik, A. M., Guthrie, C., & Yamamoto, K. R. (2010) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1924 · Cited by 128 · see citing works

Nova autoregulation reveals dual functions in neuronal splicing

Dredge, B. K., Stefani, G., Engelhard, C. C., & Darnell, R. B. (2005) · The EMBO Journal · doi:10.1038/sj.emboj.7600630 · Cited by 125 · see citing works

Global analysis of positive and negative pre-mRNA splicing regulators in DrosophilaPreprint

Blanchette, M., Green, R. E., Brenner, S. E., & Rio, D. C. (2005) · Genes & Development · doi:10.1101/gad.1314205 · Cited by 124 · see citing works

Sam68 Regulates a Set of Alternatively Spliced Exons during Neurogenesis

Chawla, G., Lin, C.-H., Han, A., Shiue, L., Ares, M., & Black, D. L. (2008) · Molecular and Cellular Biology · doi:10.1128/mcb.01349-08 · Cited by 124 · see citing works

Genome-Wide Array Analysis of Normal and Malformed Human Hearts

Kaynak, B. L., von Heydebreck, A., Mebus, S., Seelow, D., Hennig, S., Vogel, J. H., Sperling, H.-P., Pregla, R., Alexi-Meskishvili, V. V., Hetzer, R., et al. (2003) · Circulation · doi:10.1161/01.cir.0000066694.21510.e2 · Cited by 123 · see citing works

Nova Regulates GABA A Receptor γ2 Alternative Splicing via a Distal Downstream UCAU-Rich Intronic Splicing Enhancer

Dredge, B. K., & Darnell, R. B. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.13.4687-4700.2003 · Cited by 120 · see citing works

Autoregulation of Fox protein expression to produce dominant negative splicing factors

Damianov, A., & Black, D. L. (2010) · RNA · doi:10.1261/rna.1838210 · Cited by 120 · see citing works

Functional coordination of alternative splicing in the mammalian central nervous system

Fagnani, M., Barash, Y., Ip, J. Y., Misquitta, C., Pan, Q., Saltzman, A. L., Shai, O., Lee, L., Rozenhek, A., Mohammad, N., et al. (2007) · Genome Biology · doi:10.1186/gb-2007-8-6-r108 · Cited by 120 · see citing works

Fox-2 Splicing Factor Binds to a Conserved Intron Motif to Promote Inclusion of Protein \n4.1R Alternative Exon 16

Ponthier, J. L., Schluepen, C., Chen, W., Lersch, R., Gee, S. L., Hou, V., Lo, A., Short, S. A., Chasis, J. A., Winkelmann, J. C., et al. (2006) · eScholarship (California Digital Library) · Cited by 119 · see citing works

Computational analysis of candidate intron regulatory elements for tissue-specific alternative pre-mRNA splicing

Brudno, M. (2001) · Nucleic Acids Research · doi:10.1093/nar/29.11.2338 · Cited by 119 · see citing works

Splicing, transcription, and chromatin: a ménage à trois.

Allemand, E., Batsché, E., & Muchardt, C. (2008) · Current Opinion in Genetics and Development · doi:10.1016/j.gde.2008.01.006 · Cited by 118 · see citing works

A bichromatic fluorescent reporter for cell-based screens of alternative splicing

Orengo, J. P., Bundman, D. S., & Cooper, T. A. (2006) · Nucleic Acids Research · doi:10.1093/nar/gkl967 · Cited by 118 · see citing works

Human QKI, a new candidate gene for schizophrenia involved in myelination

Åberg, K. A., Saetre, P., Lindholm, E., Ekholm, B., Pettersson, U., Adolfsson, R., & JAZIN, E. E. (2005) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30243 · Cited by 116 · see citing works

Exon-Level Microarray Analyses Identify Alternative Splicing Programs in Breast Cancer

Lapuk, A. V., Marr, H., Jakkula, L. R., Pedro, H., Bhattacharya, S., Purdom, E. A., Hu, Z., Simpson, K., Pachter, L. S., Durinck, S., et al. (2010) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-09-0528 · Cited by 116 · see citing works

Rescuing Z ⁺ agrin splicing in <i>Nova</i> null mice restores synapse formation and unmasks a physiologic defect in motor neuron firing

Ruggiu, M., Herbst, R., Kim, N., Jevsek, M., Fak, J. J., Mann, M. A., Fischbach, G., Burden, S. J., & Darnell, R. B. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0813112106 · Cited by 113 · see citing works

The PTB interacting protein raver1 regulates α‐tropomyosin alternative splicing

Gromak, N., Rideau, A., Southby, J., Scadden, A. D. J., Gooding, C., Hüttelmaier, S., Singer, R. H., & Smith, C. W. J. (2003) · The EMBO Journal · doi:10.1093/emboj/cdg609 · Cited by 111 · see citing works

Caenorhabditis elegans: a model system for systems neuroscience

Sengupta, P., & Samuel, A. D. T. (2009) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2009.09.009 · Cited by 109 · see citing works

The splicing regulatory element, UGCAUG, is phylogenetically and spatially conserved in introns that flank tissue-specific alternative exons

Minovitsky, S. (2005) · Nucleic Acids Research · doi:10.1093/nar/gki210 · Cited by 103 · see citing works

Systematic genome-wide annotation of spliceosomal proteins reveals differential gene family expansionPreprint

Barbosa‐Morais, N. L., Carmo‐Fonseca, M., & Aparicio, S. A. J. R. (2005) · Genome Research · doi:10.1101/gr.3936206 · Cited by 98 · see citing works

Alternative splicing of mouse transcription factors affects their DNA-binding domain architecture and is tissue specific

Taneri, B., Snyder, B., Novoradovsky, A., & Gaasterland, T. (2004) · Genome biology · doi:10.1186/gb-2004-5-10-r75 · Cited by 92 · see citing works

Regulation of Alternative Splicing by Signal Transduction Pathways

Lynch, K. W. (2007) · Advances in experimental medicine and biology · doi:10.1007/978-0-387-77374-2_10 · Cited by 84 · see citing works

In vivo transcriptional profile analysis reveals RNA splicing and chromatin remodeling as prominent processes for adult neurogenesis

Lim, D. A., Suárez‐Fariñas, M., Naef, F., Hacker, C. R., Menn, B., Takebayashi, H., Magnasco, M. O., Patil, N., & Álvarez-Buylla, A. (2005) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2005.10.005 · Cited by 81 · see citing works

Exon Silencing by UAGG Motifs in Response to Neuronal Excitation

An, P., & Grabowski, P. J. (2007) · PLoS Biology · doi:10.1371/journal.pbio.0050036 · Cited by 79 · see citing works

Global analysis of mRNA splicing

Moore, M. J., & Silver, P. A. (2007) · RNA · doi:10.1261/rna.868008 · Cited by 79 · see citing works

Visualization and genetic analysis of alternative splicing regulation in vivo using fluorescence reporters in transgenic Caenorhabditis elegans

Kuroyanagi, H., Ohno, G., Sakane, H., Maruoka, H., & Hagiwara, M. (2010) · Nature Protocols · doi:10.1038/nprot.2010.107 · Cited by 73 · see citing works

Quaking I controls a unique cytoplasmic pathway that regulates alternative splicing of myelin-associated glycoprotein

Zhao, L., Mandler, M. D., Yi, H., & Feng, Y. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1007487107 · Cited by 70 · see citing works

Global analysis reveals SRp20- and SRp75-specific mRNPs in cycling and neural cells

Änkö, M., Morales, L., Henry, I., Beyer, A., & Neugebauer, K. M. (2010) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1862 · Cited by 67 · see citing works

Structural genomics analysis of alternative splicing and application to isoform structure modeling

Wang, P., Yan, B., Guo, J., Hicks, C., & Xu, Y. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0506770102 · Cited by 67 · see citing works

Alternative Splicing Regulation During C. elegans Development: Splicing Factors as Regulated Targets

Barberán-Soler, S., & Zahler, A. M. (2008) · PLoS Genetics · doi:10.1371/journal.pgen.1000001 · Cited by 64 · see citing works

Coevolutionary networks of splicing cis -regulatory elements

Xiao, X. G., Wang, Z., Jang, M., & Burge, C. B. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0707349104 · Cited by 60 · see citing works

The CTD role in cotranscriptional RNA processing and surveillance

de Almeida, S. F., & Carmo‐Fonseca, M. (2008) · FEBS Letters · doi:10.1016/j.febslet.2008.04.019 · Cited by 60 · see citing works

Regulation of alternative splicing by short non-coding nuclear RNAs

Khanna, A., & Stamm, S. (2010) · RNA Biology · doi:10.4161/rna.7.4.12746 · Cited by 56 · see citing works

Invertebrate studies and their ongoing contributions to neuroscience

Sattelle, D. B., & Buckingham, S. D. (2006) · Invertebrate Neuroscience · doi:10.1007/s10158-005-0014-7 · Cited by 54 · see citing works

Motor coordination defects in mice deficient for the Sam68 RNA-binding protein

Lukong, K. E., & Richard, S. (2008) · Behavioural Brain Research · doi:10.1016/j.bbr.2008.01.010 · Cited by 48 · see citing works

Global analysis of alternative splicing regulation by insulin and wingless signaling in Drosophilacells

Hartmann, B., Castelo, R., Blanchette, M., Boué, S., Rio, D. C., & Valcárcel, J. (2009) · Genome biology · doi:10.1186/gb-2009-10-1-r11 · Cited by 43 · see citing works

Regulation of gene expression by the RNA-binding protein Sam68 in cancer

Rajan, P., Gaughan, L., Dalgliesh, C., El‐Sherif, A., Robson, C. N., Leung, H. Y., & Elliott, D. J. (2008) · Biochemical Society Transactions · doi:10.1042/bst0360505 · Cited by 42 · see citing works

The role of CELF proteins in neurological disorders

Gallo, J., & Spickett, C. (2010) · RNA Biology · doi:10.4161/rna.7.4.12345 · Cited by 41 · see citing works

A protocol for imaging alternative splicing regulation in vivo using fluorescence reporters in transgenic mice

Bonano, V. I., Oltean, S., & García-Blanco, M. A. (2007) · Nature Protocols · doi:10.1038/nprot.2007.292 · Cited by 40 · see citing works

The CUGBP2 Splicing Factor Regulates an Ensemble of Branchpoints from Perimeter Binding Sites with Implications for Autoregulation

Dembowski, J. A., & Grabowski, P. J. (2009) · PLoS Genetics · doi:10.1371/journal.pgen.1000595 · Cited by 35 · see citing works

Technologies for the Global Discovery and Analysis of Alternative Splicing

Calarco, J. A., Saltzman, A. L., Ip, J. Y. Y., & Blencowe, B. J. (2007) · Advances in experimental medicine and biology · doi:10.1007/978-0-387-77374-2_5 · Cited by 33 · see citing works

Intronic motif pairs cooperate across exons to promote pre-mRNA splicing

Ke, S., & Chasin, L. A. (2010) · Genome biology · doi:10.1186/gb-2010-11-8-r84 · Cited by 33 · see citing works

Specific interaction between Sam68 and neuronal mRNAs: Implication for the activity‐dependent biosynthesis of elongation factor eEF1A

Grange, J., Belly, A., Dupas, S., Trembleau, A., Sadoul, R., & Goldberg, Y. (2008) · Journal of Neuroscience Research · doi:10.1002/jnr.21824 · Cited by 30 · see citing works

Use of transcriptional synergy to augment sensitivity of a splicing reporter assay

Levinson, N., Hinman, R. M., Patil, A., Stephenson, C. R. J., Werner, S., Woo, G. H. C., Xiao, J., Wipf, P., & Lynch, K. W. (2006) · RNA · doi:10.1261/rna.8306 · Cited by 21 · see citing works

Functional and Mechanistic Insights From Genome-Wide Studies of Splicing Regulation in the Brain

Ule, J., & Darnell, R. B. (2007) · Advances in experimental medicine and biology · doi:10.1007/978-0-387-77374-2_9 · Cited by 21 · see citing works

Ab initio identification of functionally interacting pairs of cis-regulatory elementsPreprint

Friedman, B. A., Stadler, M. B., Shomron, N., Ding, Y., & Burge, C. B. (2008) · Genome Research · doi:10.1101/gr.080085.108 · Cited by 17 · see citing works

Functional consequences of developmentally regulated alternative splicing

Kalsotra, A., & Cooper, T. A. (2011) · Nature Reviews Genetics · doi:10.1038/nrg3052 · Cited by 729 · see citing works

A Highly Conserved Program of Neuronal Microexons Is Misregulated in Autistic Brains

Irimia, M., Weatheritt, R. J., Ellis, J. D., Parikshak, N. N., Gonatopoulos-Pournatzis, T., Babor, M., Quesnel-Vallières, M., Tapial, J., Raj, B., O’Hanlon, D., et al. (2014) · Cell · doi:10.1016/j.cell.2014.11.035 · Cited by 693 · see citing works

Alternative Splicing in the Mammalian Nervous System: Recent Insights into Mechanisms and Functional Roles

Raj, B., & Blencowe, B. J. (2015) · Neuron · doi:10.1016/j.neuron.2015.05.004 · Cited by 475 · see citing works

Tissue-specific alternative splicing remodels protein-protein interaction networks

Ellis, J. D., Barrios-Rodiles, M., Çolak, R., Irimia, M., Kim, T., Calarco, J. A., Wang, X., Pan, Q., O'Hanlon, D., Kim, P. M., et al. (2012) · Molecular Cell · doi:10.1016/j.molcel.2012.05.037 · Cited by 431 · see citing works

Neurogenesis during development of the vertebrate central nervous system

Paridaen, J. T. M. L., & Huttner, W. Β. (2014) · EMBO Reports · doi:10.1002/embr.201438447 · Cited by 390 · see citing works

The neurogenetics of alternative splicing

Vuong, C. K., Black, D. L., & Zheng, S. (2016) · Nature Reviews Neuroscience · doi:10.1038/nrn.2016.27 · Cited by 340 · see citing works

RBFOX1 regulates both splicing and transcriptional networks in human neuronal development

Fogel, B. L., Wexler, E., Wahnich, A., Friedrich, T., Vijayendran, C., Gao, F., Parikshak, N., Konopka, G., & Geschwind, D. H. (2012) · Human Molecular Genetics · doi:10.1093/hmg/dds240 · Cited by 216 · see citing works

Neuronal Elav-like (Hu) proteins regulate RNA splicing and abundance to control glutamate levels and neuronal excitability

Ince-Dunn, G., Okano, H. J., Jensen, K. B., Park, W.-Y., Zhong, R., Ule, J., Mele, A., Fak, J. J., Yang, C., Zhang, C., et al. (2012) · Neuron · doi:10.1016/j.neuron.2012.07.009 · Cited by 212 · see citing works

RNA Protein Interaction in Neurons

Darnell, R. B. (2013) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-062912-114322 · Cited by 181 · see citing works

Alternative splicing: decoding an expansive regulatory layer

Irimia, M., & Blencowe, B. J. (2012) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2012.03.005 · Cited by 177 · see citing works

The splicing regulator PTBP2 controls a program of embryonic splicing required for neuronal maturation

Li, Q., Zheng, S., Han, A., Lin, C.-H., Stoilov, P., Fu, X.-D., & Black, D. L. (2014) · eLife · doi:10.7554/elife.01201 · Cited by 174 · see citing works

Cross-Regulation between an Alternative Splicing Activator and a Transcription Repressor Controls Neurogenesis

Raj, B., O'Hanlon, D., Vessey, J. P., Pan, Q., Ray, D., Buckley, N. J., Miller, F. D., & Blencowe, B. J. (2011) · Molecular Cell · doi:10.1016/j.molcel.2011.08.014 · Cited by 143 · see citing works

Protein moonlighting: a new factor in biology and medicine

Henderson, B. E., & Martin, A. C. R. (2014) · Biochemical Society Transactions · doi:10.1042/bst20140273 · Cited by 106 · see citing works

Phosphorylation of SRSF1 by SRPK1 regulates alternative splicing of tumor-related Rac1b in colorectal cells

Gonçalves, V., Henriques, A. F. A., Pereira, J. C., Neves‐Costa, A., Moyer, M. P., Moita, L. F., Gama‐Carvalho, M., Matos, P., & Jordan, P. (2014) · RNA · doi:10.1261/rna.041376.113 · Cited by 106 · see citing works

Regulation of alternative splicing of tau exon 10

Qian, W., & Liu, F. (2014) · Neuroscience Bulletin · doi:10.1007/s12264-013-1411-2 · Cited by 105 · see citing works

Synthetic oligonucleotides recruit ILF2/3 to RNA transcripts to modulate splicing

Rigo, F., Hua, Y., Chun, S. J., Prakash, T. P., Krainer, A. R., & Bennett, C. F. (2012) · Nature Chemical Biology · doi:10.1038/nchembio.939 · Cited by 102 · see citing works

Alcohol and NMDA receptor: current research and future direction

Chandrasekar, R. (2013) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2013.00014 · Cited by 101 · see citing works

Post-transcriptional RNA regulons affecting cell cycle and proliferation

Blackinton, J. G., & Keene, J. D. (2014) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2014.05.014 · Cited by 95 · see citing works

The Tissue-Specific RNA Binding Protein T-STAR Controls Regional Splicing Patterns of Neurexin Pre-mRNAs in the Brain

Ehrmann, I., Dalgliesh, C., Liu, Y., Danilenko, M., Crosier, M., Overman, L., Arthur, H. M., Lindsay, S., Clowry, G. J., Venables, J. P., et al. (2013) · PLoS Genetics · doi:10.1371/journal.pgen.1003474 · Cited by 82 · see citing works

BCAS2 is involved in alternative mRNA splicing in spermatogonia and the transition to meiosis

Liu, W., Wang, F., Xu, Q., Shi, J., Zhang, X., Lu, X., Zhao, Z., Gao, Z., Ma, H., Duan, E., et al. (2017) · Nature Communications · doi:10.1038/ncomms14182 · Cited by 79 · see citing works

ELAVL2-regulated transcriptional and splicing networks in human neurons link neurodevelopment and autism

Berto, S., Usui, N., Konopka, G., & Fogel, B. L. (2016) · Human Molecular Genetics · doi:10.1093/hmg/ddw110 · Cited by 80 · see citing works

Regulation of gene expression in mammalian nervous system through alternative pre-mRNA splicing coupled with RNA quality control mechanisms

Yap, K., & Makeyev, E. V. (2013) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2013.01.003 · Cited by 75 · see citing works

Splicing: is there an alternative contribution to Parkinson’s disease?

Cognata, V. L., D’Agata, V., Cavalcanti, F., & Cavallaro, S. (2015) · Neurogenetics · doi:10.1007/s10048-015-0449-x · Cited by 74 · see citing works

Antisense Oligonucleotide-Based Therapies for Diseases Caused by pre-mRNA Processing Defects

Rigo, F., Seth, P. P., & Bennett, C. F. (2014) · Advances in experimental medicine and biology · doi:10.1007/978-1-4939-1221-6_9 · Cited by 71 · see citing works

Neuron-enriched RNA-binding Proteins Regulate Pancreatic Beta Cell Function and Survival

Juan‐Mateu, J., Rech, T. H., Villate, O., Lizárraga-Mollinedo, E., Wendt, A., Turatsinze, J., Brondani, L. D. A., Nardelli, T. R., Nogueira, T. C., Esguerra, J. L. S., et al. (2017) · Journal of Biological Chemistry · doi:10.1074/jbc.m116.748335 · Cited by 70 · see citing works

Alternative Splicing of Neuronal Differentiation Factor TRF2 Regulated by HNRNPH1/H2

Grammatikakis, I., Zhang, P., Panda, A. C., Kim, J., Maudsley, S. R., Abdelmohsen, K., Yang, X., Martindale, J. L., Motiño, O., Hutchison, E. R., et al. (2016) · Cell Reports · doi:10.1016/j.celrep.2016.03.080 · Cited by 63 · see citing works

Molecular functions and specific roles of circRNAs in the cardiovascular system

Holdt, L. M., Kohlmaier, A., & Teupser, D. (2018) · Non-coding RNA Research · doi:10.1016/j.ncrna.2018.05.002 · Cited by 55 · see citing works

SRp55 Regulates a Splicing Network That Controls Human Pancreatic β-Cell Function and Survival

Juan-Mateu, J., Alvelos, M. I., Turatsinze, J., Villate, O., Lizárraga-Mollinedo, E., Grieco, F. A., Marroquí, L., Bugliani, M., Marchetti, P., & Eizirik, D. L. (2017) · Diabetes · doi:10.2337/db17-0736 · Cited by 52 · see citing works

Alternative splicing: An important mechanism in stem cell biology

Chen, K. (2015) · World Journal of Stem Cells · doi:10.4252/wjsc.v7.i1.1 · Cited by 48 · see citing works

Full-length isoform transcriptome of the developing human brain provides further insights into autism

Chau, K. K., Zhang, P., Urresti, J., Amar, M., Pramod, A. B., Chen, J., Thomas, A. E., Corominas, R., Lin, G. N., & Iakoucheva, L. M. (2021) · Cell Reports · doi:10.1016/j.celrep.2021.109631 · Cited by 42 · see citing works

Pre-mRNA splicing and its regulation in Caenorhabditis elegans

Zahler, A. M. (2012) · WormBook · doi:10.1895/wormbook.1.31.2 · Cited by 44 · see citing works

Splicing factor TRA2B is required for neural progenitor survival

Roberts, J. M., Ennajdaoui, H., Edmondson, C., Wirth, B., Sanford, J. R., & Chen, B. (2013) · The Journal of Comparative Neurology · doi:10.1002/cne.23405 · Cited by 41 · see citing works

Alternative splicing in ascomycetes

Kempken, F. (2013) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-013-4841-x · Cited by 40 · see citing works

Complex Tissue-Specific Patterns and Distribution of Multiple RAGE Splice Variants in Different Mammals

López‐Díez, R., Rastrojo, A., Villate, O., & Aguado, B. (2013) · Genome Biology and Evolution · doi:10.1093/gbe/evt188 · Cited by 39 · see citing works

Spatio-temporal regulations and functions of neuronal alternative RNA splicing in developing and adult brains

Iijima, T., Hidaka, C., & Iijima, Y. (2016) · Neuroscience Research · doi:10.1016/j.neures.2016.01.010 · Cited by 35 · see citing works

Liposomes: Novel Drug Delivery Approach for Targeting Parkinson’s Disease

Kumar, B., Pandey, M., Pottoo, F. H., Fayaz, F., Sharma, A., & Sahoo, P. K. (2020) · Current Pharmaceutical Design · doi:10.2174/1381612826666200128145124 · Cited by 32 · see citing works

Effects of selection for ethanol preference on gene expression in the nucleus accumbens of HS‐CC mice

Colville, A. M., Iancu, O. D., Oberbeck, D. L., Darakjian, P., ZHENG, C. L., Walter, N. A. R., Harrington, C. A., Searles, R. P., McWeeney, S. K., & Hitzemann, R. (2017) · Genes Brain & Behavior · doi:10.1111/gbb.12367 · Cited by 26 · see citing works

Alternative splicing regulation of APP exon 7 by RBFox proteins

Alam, S., Suzuki, H., & Tsukahara, T. (2014) · Neurochemistry International · doi:10.1016/j.neuint.2014.08.001 · Cited by 25 · see citing works

Identification of neural stem cell differentiation repressor complex Pnky-PTBP1

Grammatikakis, I., & Gorospe, M. (2016) · Stem Cell Investigation · doi:10.21037/sci.2016.03.05 · Cited by 22 · see citing works

An Integrated Regulatory Network Reveals Pervasive Cross-Regulation among Transcription and Splicing Factors

Kosti, I., Predrag Radivojac, A., & Mandel‐Gutfreund, Y. (2012) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1002603 · Cited by 20 · see citing works

Towards improved genome-scale metabolic network reconstructions: unification, transcript specificity and beyond

Pfau, T., Pacheco, M. P., & Sauter, T. (2015) · Briefings in Bioinformatics · doi:10.1093/bib/bbv100 · Cited by 20 · see citing works

SRRM4 Expands the Repertoire of Circular RNAs by Regulating Microexon Inclusion

Conn, V. M., Gabryelska, M., Marri, S., Stringer, B. W., Ormsby, R. J., Penn, T., Poonnoose, S. I., Kichenadasse, G., & Conn, S. J. (2020) · Cells · doi:10.3390/cells9112488 · Cited by 20 · see citing works

Sxl-Dependent,tra/tra2-Independent Alternative Splicing of theDrosophila melanogasterX-Linked Genefound in neurons

Sun, X., Yang, H., Sturgill, D. M., Oliver, B., Rabinow, L., & Samson, M. (2015) · G3 Genes Genomes Genetics · doi:10.1534/g3.115.023721 · Cited by 20 · see citing works

Transcriptional Elongation Regulator 1 Affects Transcription and Splicing of Genes Associated with Cellular Morphology and Cytoskeleton Dynamics and Is Required for Neurite Outgrowth in Neuroblastoma Cells and Primary Neuronal Cultures

Muñoz-Cobo, J. P., Sánchez-Hernández, N., Gutiérrez, S., Yousfi, Y. E., Montes, M., Gallego, C., Hernández-Munaín, C., & Suñé, C. (2016) · Molecular Neurobiology · doi:10.1007/s12035-016-0284-6 · Cited by 19 · see citing works

The combinatorial control of alternative splicing in C. elegans

Tan, J. H., & Fraser, A. G. (2017) · PLoS Genetics · doi:10.1371/journal.pgen.1007033 · Cited by 18 · see citing works

CircRNA SRRM4 affects glucose metabolism by regulating PKM alternative splicing via SRSF3 deubiquitination in epilepsy

Zhao, W., Li, M., Wang, S., Li, Z., Li, H., & Li, S. (2022) · Neuropathology and Applied Neurobiology · doi:10.1111/nan.12850 · Cited by 18 · see citing works

Evolutionary development of neural systems in vertebrates and beyond

O’Connell, L. A. (2013) · Journal of Neurogenetics · doi:10.3109/01677063.2013.789511 · Cited by 17 · see citing works

Alternative Splicing of a Novel Inducible Exon Diversifies the CASK Guanylate Kinase Domain

Dembowski, J. A., An, P., Scoulos-Hanson, M., Yeo, G. W.-M., Han, J., Fu, X., & Grabowski, P. J. (2012) · Journal of Nucleic Acids · doi:10.1155/2012/816237 · Cited by 16 · see citing works

Alternative splicing of the neurofibromatosis type 1 pre-mRNA is regulated by the muscleblind-like proteins and the CUG-BP and ELAV-like factors

Barron, V. A., Geng, C., Ladd, A. N., & Lou, H. J. (2012) · BMC Molecular Biology · doi:10.1186/1471-2199-13-35 · Cited by 15 · see citing works

Networks of mRNA Processing and Alternative Splicing Regulation in Health and Disease

Jordan, P., Gonçalves, V., Fernandes, S., Marques, T. M., Pereira, M. H. N., & Gama‐Carvalho, M. (2019) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-19966-1_1 · Cited by 15 · see citing works

Coexpression and Cosplicing Network Approaches for the Study of Mammalian Brain Transcriptomes

Iancu, O. D., Colville, A. M., Darakjian, P., & HITZEMANN, R. J. (2014) · International review of neurobiology · doi:10.1016/b978-0-12-801105-8.00004-7 · Cited by 12 · see citing works

Development of aDrosophila melanogasterspliceosensor system forin vivohigh-throughput screening in myotonic dystrophy type 1

García-Alcover, I., Colonques-Bellmunt, J., Garijo, R., Tormo, J. R., Artero, R. D., Álvarez-Abril, M. C., López, A., & Pérez‐Alonso, M. (2014) · Disease Models & Mechanisms · doi:10.1242/dmm.016592 · Cited by 15 · see citing works

Regulation of Tissue-Specific Alternative Splicing: C. elegans as a Model System

Gracida, X., Norris, A. D., & Calarco, J. A. (2016) · Advances in experimental medicine and biology · doi:10.1007/978-3-319-29073-7_10 · Cited by 14 · see citing works

Bioinformatics challenges and perspectives when studying the effect of epigenetic modifications on alternative splicing

Pacini, C., & Koziol, M. J. (2018) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2017.0073 · Cited by 13 · see citing works

Comparative genomics reveals tissue-specific regulation of prolactin receptor gene expression

Schennink, A., Trott, J. F., Manjarín, R., Lemay, D. G., Freking, B. A., & Hovey, R. C. (2014) · Journal of Molecular Endocrinology · doi:10.1530/jme-14-0212 · Cited by 13 · see citing works

Non-coding RNAs derived from an alternatively spliced REST transcript (REST-003) regulate breast cancer invasiveness

Lee, N. S., Evgrafov, O. V., Souaiaia, T., Bonyad, A., Herstein, J. S., Lee, J. Y., Kim, J., Ning, Y., Sixto, M., Weitz, A. C., et al. (2015) · Scientific Reports · doi:10.1038/srep11207 · Cited by 12 · see citing works

Multifunctional RNA Processing Protein SRm160 Induces Apoptosis and Regulates Eye and Genital Development in Drosophila

Fan, Y., Gittis, A. H., Juge, F., Qiu, C., Xu, Y.-Z., & Rabinow, L. (2014) · Genetics · doi:10.1534/genetics.114.164434 · Cited by 11 · see citing works

Bioinformatics Approaches for Studying Alternative Splicing

Thakur, P. K., Rawal, H. C., Obuća, M., & Kaushik, S. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-809633-8.20228-8 · Cited by 10 · see citing works

Spliceosomal genes in the D. discoideum genome: a comparison with those in H. sapiens, D. melanogaster, A. thaliana and S. cerevisiae

Yu, B., Fey, P., Pilcher, K. E., Fedorov, A. N., Prakash, A., Chisholm, R. L., & Wu, J. Y. (2011) · Protein & Cell · doi:10.1007/s13238-011-1052-z · Cited by 9 · see citing works

Putting Humpty–Dumpty Together

Rohlman, C. E., Blanco, M. R., & Walter, N. G. (2016) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/bs.mie.2016.08.022 · Cited by 4 · see citing works

Spliceosomal Proteins Encoded by Fungal Genomes

Sarde, S. J., Kempken, F., & Kumar, A. (2018) · Current Science · doi:10.18520/cs/v114/i08/1677-1686 · Cited by 3 · see citing works

An impaired splicing program underlies differentiation defects in hSOD1G93A neural progenitor cells

Verdile, V., Riccioni, V., Guerra, M., Ferrante, G., Sette, C., Valle, C., Ferri, A., & Paronetto, M. P. (2023) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-023-04893-7 · Cited by 3 · see citing works

Full-length isoform transcriptome of developing human brain provides new insights into autismPreprint

Chau, K., Zhang, P., Urresti, J., Amar, M., Pramod, A. B., Chen, J., Thomas, A., Corominas, R., Lin, G. N., & Iakoucheva, L. M. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.06.27.175489 · Cited by 2 · see citing works

Biological Consequences of Protein Moonlighting

Henderson, B. E., Fares, M. A., & Martin, A. C. R. (2016) · Wiley eBooks · doi:10.1002/9781118952108.ch6 · Cited by 1 · see citing works

Recent Advances in Understanding of Alternative Splicing in Neuronal Pathogenesis

Chen, H.-H., Lin, J.-C., & Tar, W.-Y. (2011) · InTech eBooks · doi:10.5772/22477

mRNA Variants of a Neuronal Sodium Channel in Rat Cardiac Myocytes

Lafreniere, G. (2015) · QSpace (Queen's University Library)

Regulation of Core Splicing Factors by Alternative Splicing and Nonsense-mediated mRNA Decay

Saltzman, A. L. (2012) · TSpace (University of Toronto)

NEUROSPECIFIC LSD1 SPLICING ISOFORM LINKS EPIGENETICS TO MAMMALIAN BRAIN PHYSIOLOGY

Paganini, L. (2013) · Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano) · doi:10.13130/paganini-leda_phd2013-01-31

A Genome-Scale Analysis of Alternative Splicing Regulation by Splicing Factors in C. elegans

Tan, J. H. (2018) · TSpace (University of Toronto)

Preferential α-Pro-GDNF Expression is Associated with Glioblastoma Cell MigrationPreprint

Li, H., Zhang, L., Cao, Y., He, T., Chai, X., He, W., Yu, R., & Gao, D. (2021) · SSRN Electronic Journal · doi:10.2139/ssrn.3986224

Fast recontruction of compact context-specific network modelsPreprint

Pacheco, M. P. (2018) · doi:10.31237/osf.io/8xcwa

Comprendre le rôle des complexes de modification de l’ARNt ADAT3/ADAT2 & WDR4/METTL1 pendant le développement du cortex cérébral

Del-Pozo-Rodríguez, J. (2020) · theses.fr (ABES) · doi:10.70675/c4e031efz0a8bz4cfaz93abza990eb954d53

Cell-type-specific splicing factors and the regulation of alternative RNA splicing.

Latchman, D. S. (1990) · PubMed · Cited by 36 · see citing works

Functional roles of alternative splicing factors in human disease

Cieply, B. W., & Carstens, R. P. (2015) · Wiley Interdisciplinary Reviews - RNA · doi:10.1002/wrna.1276 · Cited by 142 · see citing works

Functional and Mechanistic Analyses of Neural-regulated Alternative Splicing

Raj, B. N. (2015) · TSpace (University of Toronto)

Systematic exploration of dynamic splicing networks reveals conserved multistage regulators of neurogenesis

Han, H. R., Best, A. J., Braunschweig, U., Mikolajewicz, N., Li, J. D., Roth, J. F., Chowdhury, F., Mantica, F., Nabeel‐Shah, S., Parada, G. E., et al. (2022) · Molecular Cell · doi:10.1016/j.molcel.2022.06.036 · Cited by 25 · see citing works

Multilayered Control of Alternative Splicing Regulatory Networks by Transcription Factors

Han, H. R., Braunschweig, U., Gonatopoulos-Pournatzis, T., Weatheritt, R. J., Hirsch, C. L., Ha, K., Radovani, E., Nabeel‐Shah, S., Sterne‐Weiler, T., Wang, J., et al. (2017) · Molecular Cell · doi:10.1016/j.molcel.2017.01.011 · Cited by 177 · see citing works