Nutrition, gut microbiota, and alzheimer’s disease
Open accessAbstract
Nutrition is known to play an important role in the pathogenesis of Alzheimer's disease. Evidence is obtained that the gut microbiota is a key player in these processes. Dietary changes (both adverse and beneficial) may influence the microbiome composition, thereby affecting the gut-brain axis and the subsequent risk for Alzheimer's disease progression. In this review, the research findings that support the role of intestinal microbiota in connection between nutritional factors and the risk for Alzheimer's disease onset and progression are summarized. The mechanisms potentially involved in these processes as well as the potential of probiotics and prebiotics in therapeutic modulation of contributed pathways are discussed.
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The positive effects of a GM-favorable diet are likely due to the availability of prebiotics, probiotics, SCFAs, and polyphenols.
“This is likely due to the availability of prebiotics, probiotics, SCFAs, and polyphenols.”
From Signalling cognition: The gut microbiota and hypothalamic-pituitary-adrenal axis (2023) · cites this paper as [510]
A significant body of evidence demonstrates that consuming a GM-favorable diet can positively influence the GM, improve health status, and enhance cognitive function.
“A comprehensive review of this topic is beyond the scope of this review, however, a significant body of evidence demonstrates that consuming a GM-favorable diet can positively influence the GM, improve health status, and enhance cognitive function (506–510).”
From Signalling cognition: The gut microbiota and hypothalamic-pituitary-adrenal axis (2023) · cites this paper as [510]
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Long Covid, the Gut, and Autoimmune Skin Diseases: A Novel Therapeutic ApproachPreprint
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Gut Microbiome Changes in Preclinical Alzheimer’s Disease
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- Authors
- Romanenko, M., Kholin, V., Koliada, A., & Vaiserman, A.
- Affiliations
- D. F. Chebotarev State Institute of Gerontology of the National Academy of Medical Sciences of Ukraine (UA)
- Corresponding author
- Romanenko, Mariana
- Venue
- Frontiers in Psychiatry
- Publisher
- Frontiers Media SA
- Published
- 2021-08-05
- Volume
- 12
- Pages
- 712673-712673
- ISSN
- 1664-0640 (ISSN-L)
- PMC
- PMC8374099
- OpenAlex
- W3188826759
- Cited by
- 56
- References
- 137
- Citations by year
- 2026: 7 · 2025: 7 · 2024: 20 · 2023: 12 · 2022: 7 · 2021: 3
- FWCI
- 1.10
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Frontiers in Psychiatry (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Health Sciences › Medicine › Physiology › Alzheimer's disease research and treatments
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Keywords
- Alzheimer's disease, gut microbiota, nutrition, gut-brain axis, dietary factors, microbiota composition, probiotics, prebiotics, disease progression, neurodegeneration
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