Cited by 342Polysaccharides Composition and ApplicationsProbiotics and Fermented FoodsMicrobial Metabolites in Food Biotechnology

The DOI matches its Crossref record; 231 of the 235 references it cites were found in a registry or an index, and 1 are not checked yet.

Exopolysaccharides Produced by Lactic Acid Bacteria: From Biosynthesis to Health-Promoting Properties

Open access

Jurášková, Dominika, Ribeiro, Susana C., Silva, Celia C. G.·2022·Foods

DOI 10.3390/foods11020156PMC PMC8774684

Open this paper in CoChat — free account Open PDF

Abstract

The production of exopolysaccharides (EPS) by lactic acid bacteria (LAB) has attracted particular interest in the food industry. EPS can be considered as natural biothickeners as they are produced in situ by LAB and improve the rheological properties of fermented foods. Moreover, much research has been conducted on the beneficial effects of EPS produced by LAB on modulating the gut microbiome and promoting health. The EPS, which varies widely in composition and structure, may have diverse health effects, such as glycemic control, calcium and magnesium absorption, cholesterol-lowering, anticarcinogenic, immunomodulatory, and antioxidant effects. In this article, the latest advances on structure, biosynthesis, and physicochemical properties of LAB-derived EPS are described in detail. This is followed by a summary of up-to-date methods used to detect, characterize and elucidate the structure of EPS produced by LAB. In addition, current strategies on the use of LAB-produced EPS in food products have been discussed, focusing on beneficial applications in dairy products, gluten-free bakery products, and low-fat meat products, as they positively influence the consistency, stability, and quality of the final product. Highlighting is also placed on reports of health-promoting effects, with particular emphasis on prebiotic, immunomodulatory, antioxidant, cholesterol-lowering, anti-biofilm, antimicrobial, anticancer, and drug-delivery activities.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.3390/foods11020156

Cites

231 of 232 references verified0 citation errors · 0 not checkable

Statistics

Figure 1 Characteristics of EPS produced by LAB: (a) Mucoid colonies—slimy phenotype; (b) Ropy phenotype.CC BY · PubMed Central

Figure 2 Flow chart for isolation, purification steps (I—first purification, II—second purification), and characterization of EPS.CC BY · PubMed Central

Figure 3 Biological and functional activities exerted by EPS produced by LAB.CC BY · PubMed Central

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Colorimetric Method for Determination of Sugars and Related Substances
DuBois, M., Gilles, K. A., Hamilton, J. K., Rebers, P. A., & Smith, F. (1956) · Analytical Chemistry · doi:10.1021/ac60111a017 · Cited by 52,269
The Carbohydrate-Active EnZymes database (CAZy): an expert resource for Glycogenomics
Cantarel, B. L., Coutinho, P. M., Rancurel, C., Bernard, T., Lombard, V., & Henrissat, B. (2008) · Nucleic Acids Research · doi:10.1093/nar/gkn663 · Cited by 6,108
A taxonomic note on the genus lactobacillus: description of 23 novel genera, emended description of the genus lactobacillus Beijerinck 1901, and union of Lactobacillaceae and Leuconostocaceae
Zheng, J., Wittouck, S., Salvetti, E., Franz, C. M. A. P., Harris, H. M. B., Mattarelli, P., O’Toole, P. W., Pot, B., Vandamme, P., Walter, J., et al. (2020) · International Journal of Systematic and Evolutionary Microbiology · doi:10.1099/ijsem.0.004107 · Cited by 3,313
Making sense of the "clean label" trends: A review of consumer food choice behavior and discussion of industry implications.
Asioli, D., Aschemann-Witzel, J., Caputo, V., Vecchio, R., Annunziata, A., Næs, T., & Varela, P. (2017) · Food Research International · doi:10.1016/j.foodres.2017.07.022 · Cited by 997
Heteropolysaccharides from lactic acid bacteria
Vuyst, L. D., & Degeest, B. (1999) · FEMS Microbiology Reviews · doi:10.1111/j.1574-6976.1999.tb00395.x · Cited by 840
Advances in bacterial exopolysaccharides: from production to Biotechnological applications
Freitas, F., Alves, V. D., & Reis, M. A. M. (2011) · Trends in Biotechnology · doi:10.1016/j.tibtech.2011.03.008 · Cited by 804
A new method for rapid determination of carbohydrate and total carbon concentrations using UV spectrophotometry
Albalasmeh, A. A., Berhe, A. A., & Ghezzehei, T. A. (2013) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2013.04.072 · Cited by 760
Bacterial Exopolysaccharides: Functionality and Prospects
Nwodo, U. U., Green, E., & Okoh, A. I. (2012) · International Journal of Molecular Sciences · doi:10.3390/ijms131114002 · Cited by 706
Polysaccharide Immunomodulators as Therapeutic Agents: Structural Aspects and Biologic Function
Tzianabos, A. O. (2000) · Clinical Microbiology Reviews · doi:10.1128/cmr.13.4.523-533.2000 · Cited by 686
Bacterial exopolysaccharides: biosynthesis pathways and engineering strategies
Schmid, J., Sieber, V., & Rehm, B. H. A. (2015) · Frontiers in Microbiology · doi:10.3389/fmicb.2015.00496 · Cited by 644
An overview of the functionality of exopolysaccharides produced by lactic acid bacteria
Ruas‐Madiedo, P., Hugenholtz, J., & Zoon, P. (2002) · International Dairy Journal · doi:10.1016/s0958-6946(01)00160-1 · Cited by 640
Exopolysaccharides from Probiotic Bacteria and Their Health Potential
Angelin, J., & Kavitha, M. (2020) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2020.06.190 · Cited by 617
Lactic acid bacteria contribution to gut microbiota complexity: lights and shadows.
Pessione, E. (2012) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2012.00086 · Cited by 592
Inulin, a flexible oligosaccharide I: Review of its physicochemical characteristics
Mensink, M. A., Frijlink, H. W., Maarschalk, K. V. D. V., & Hinrichs, W. L. J. (2015) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2015.05.026 · Cited by 523
Exopolysaccharides from lactic acid bacteria: perspectives and challenges
Welman, A. D., & Maddox, I. S. (2003) · Trends in biotechnology · doi:10.1016/s0167-7799(03)00107-0 · Cited by 523
New Perspectives for Lactobacilli Exopolysaccharides
Badel, S., Bernardi, T., & Michaud, P. (2011) · Biotechnology Advances · doi:10.1016/j.biotechadv.2010.08.011 · Cited by 497
Exocellular polysaccharides produced by lactic acid bacteria
Cerning, J. (1990) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.1990.tb04883.x · Cited by 470
Invited Review: Methods for the Screening, Isolation, and Characterization of Exopolysaccharides Produced by Lactic Acid Bacteria
Ruas-Madiedo, P., & de los Reyes-Gavilán, C. G. (2005) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(05)72750-8 · Cited by 456
Non-starter lactic acid bacteria used to improve cheese quality and provide health benefits
Settanni, L., & Moschetti, G. (2010) · Food Microbiology · doi:10.1016/j.fm.2010.05.023 · Cited by 456
Exopolysaccharides of lactic acid bacteria: Structure, bioactivity and associations: A review
Zhou, Y., Cui, Y., & Qu, X. (2018) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2018.11.093 · Cited by 428
Applications of exopolysaccharides in the dairy industry
Duboc, P., & Mollet, B. (2001) · International Dairy Journal · doi:10.1016/s0958-6946(01)00119-4 · Cited by 427
Physical Characterization of Exopolysaccharide Produced by Lactobacillus plantarum KF5 Isolated from Tibet Kefir
Wang, Y., Li, C., Liu, P., Ahmed, Z., Xiao, P., & Bai, X. (2010) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2010.06.013 · Cited by 407
Exopolysaccharides Produced by Lactic Acid Bacteria: From Health-Promoting Benefits to Stress Tolerance Mechanisms
Caggianiello, G., Kleerebezem, M., & Spano, G. (2016) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-016-7471-2 · Cited by 396
Recent Developments in the Biosynthesis and Applications of Heteropolysaccharides from Lactic Acid Bacteria
De Vuyst, L., De Vin, F., Vaningelgem, F., & Degeest, B. (2001) · International Dairy Journal · doi:10.1016/s0958-6946(01)00114-5 · Cited by 391
Antioxidant Activity of an Exopolysaccharide Isolated from Lactobacillus plantarum C88
Zhang, L., Liu, C., Li, D., Zhao, Y., Zhang, X., Zeng, X., Yang, Z., & Li, S. (2013) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2012.12.037 · Cited by 371
Production, Properties, and Industrial Food Application of Lactic Acid Bacteria-Derived Exopolysaccharides
Zannini, E., Waters, D. M., Coffey, A., & Arendt, E. K. (2016) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-015-7172-2 · Cited by 371
Microbial polysaccharides from Gram-negative bacteria
Sutherland, I. W. (2001) · International Dairy Journal · doi:10.1016/s0958-6946(01)00112-1 · Cited by 370
A Comprehensive Review of Anticancer, Immunomodulatory and Health Beneficial Effects of the Lactic Acid Bacteria Exopolysaccharides
Rahbar Saadat, Y., Yari Khosroushahi, A., & Pourghassem Gargari, B. (2019) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2019.04.025 · Cited by 370
Exopolysaccharides from lactic acid bacteria: Techno-functional application in the food industry
Korcz, E., & Varga, L. (2021) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2021.02.014 · Cited by 347
Homopolysaccharides from lactic acid bacteria
MONSAN, P. F., Bozonnet, S., Albenne, C., Joucla, G., Willemot, R., & Remaud‐Siméon, M. (2001) · International Dairy Journal · doi:10.1016/s0958-6946(01)00113-3 · Cited by 345
Characterization of an exopolysaccharide produced by Lactobacillus plantarum YW11 isolated from Tibet Kefir
Wang, J., Zhao, X. Y., Tian, Z., Yang, Y., & Yang, Z. (2015) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2015.03.003 · Cited by 340
Present and future medical applications of microbial exopolysaccharides
Moscovici, M. (2015) · Frontiers in Microbiology · doi:10.3389/fmicb.2015.01012 · Cited by 331
Polysaccharide Production by Lactic Acid Bacteria: From Genes to Industrial Applications
Zeidan, A. A., Poulsen, V. K., Janzen, T., Buldo, P., Derkx, P. M. F., Øregaard, G., & Neves, A. R. (2017) · FEMS Microbiology Reviews · doi:10.1093/femsre/fux017 · Cited by 326
Characterization of a Novel Exopolysaccharide with Antitumor Activity from Lactobacillus plantarum 70810
Wang, K., Li, W., Rui, X., Chen, X., Jiang, M., & Dong, M. (2014) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2013.10.036 · Cited by 325
Wound dressings from naturally-occurring polymers: A review on homopolysaccharide-based composites
Naseri‐Nosar, M., & Ziora, Z. M. (2018) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2018.02.003 · Cited by 325
Glucansucrases: mechanism of action and structure–function relationships
Monchois, V., Willemot, R., & MONSAN, P. F. (1999) · FEMS Microbiology Reviews · doi:10.1111/j.1574-6976.1999.tb00394.x · Cited by 324
Glucansucrases: Three-dimensional structures, reactions, mechanism, α-glucan analysis and their implications in biotechnology and food applications
Leemhuis, H., Pijning, T., Dobruchowska, J. M., van Leeuwen, S. S., Kralj, S., Dijkstra, B. W., & Dijkhuizen, L. (2012) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2012.06.037 · Cited by 320
Biosynthesis, characterisation, and design of bacterial exopolysaccharides from lactic acid bacteria
Laws, A. P., Gu, Y., & Marshall, V. M. (2001) · Biotechnology Advances · doi:10.1016/s0734-9750(01)00084-2 · Cited by 279
Potentials of Exopolysaccharides from Lactic Acid Bacteria
Patel, S. V., Majumder, A., & Goyal, A. (2011) · Indian Journal of Microbiology · doi:10.1007/s12088-011-0148-8 · Cited by 274
Microbial exopolysaccharides: Synthesis pathways, types and their commercial applications
Rana, S., & Upadhyay, L. S. B. (2020) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2020.04.084 · Cited by 268
Exopolysaccharides as Antimicrobial Agents: Mechanism and Spectrum of Activity
Abdalla, A. K., Ayyash, M. M., Olaimat, A. N., Osaili, T. M., Al-Nabulsi, A. A., Shah, N. P., & Holley, R. (2021) · Frontiers in Microbiology · doi:10.3389/fmicb.2021.664395 · Cited by 268
Characterization of an Exopolysaccharide with Potential Health-Benefit Properties from a Probiotic Lactobacillus plantarum RJF4
Dilna, S. V., Surya, H., Aswathy, R. G., Varsha, K. K., Sakthikumar, D. N., Pandey, A., & Nampoothiri, K. M. (2015) · LWT - Food Science and Technology · doi:10.1016/j.lwt.2015.07.040 · Cited by 262
Isolation and Characterization of Two Exopolysaccharides Produced by Lactobacillus plantarum EP56
Tallon, R., Bressollier, P., & Urdaci, M. C. (2003) · Research in Microbiology · doi:10.1016/j.resmic.2003.09.006 · Cited by 260
Contributions of exopolysaccharides from lactic acid bacteria as biotechnological tools in food, pharmaceutical, and medical applications
Daba, G. M., Elnahas, M. O., & Elkhateeb, W. A. (2021) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2021.01.110 · Cited by 241
Exopolysaccharide producing lactic acid bacteria: Their techno-functional role and potential application in gluten-free bread products
Lynch, K. M., Coffey, A., & Arendt, E. K. (2017) · Food Research International · doi:10.1016/j.foodres.2017.03.012 · Cited by 229
Production by and isolation of exopolysaccharides from Streptococcus thermophilus grown in a milk medium and evidence for their growth-associated biosynthesis
Vuyst, L. D., Vanderveken, de Ven, V., & Degeest (1998) · Journal of Applied Microbiology · doi:10.1046/j.1365-2672.1998.00445.x · Cited by 226
Current status of biotechnological production and applications of microbial exopolysaccharides
Barcelos, M. C. S., Vespermann, K. A. C., Pelissari, F. M., & Molina, G. (2019) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2019.1575791 · Cited by 226
Dietary Fibers, Prebiotics, and Exopolysaccharides Produced by Lactic Acid Bacteria: Potential Health Benefits with Special Regard to Cholesterol-Lowering Effects
Korcz, E., Kerényi, Z., & Varga, L. (2018) · Food & Function · doi:10.1039/c8fo00118a · Cited by 222
Sugar-Coated: Exopolysaccharide Producing Lactic Acid Bacteria for Food and Human Health Applications
Ryan, P. M., Ross, R. P., Fitzgerald, G. F., Caplice, N. M., & Stanton, C. (2015) · Food & Function · doi:10.1039/c4fo00529e · Cited by 221
Microbiological, Physicochemical and Rheological Properties of Fermented Soymilk Produced with Exopolysaccharide (EPS) Producing Lactic Acid Bacteria Strains
Li, C., Li, W., Chen, X., Feng, M., Rui, X., Jiang, M., & Dong, M. (2014) · LWT - Food Science and Technology · doi:10.1016/j.lwt.2014.02.025 · Cited by 219
Food and health applications of exopolysaccharides produced by lactic acid bacteria
JB Prajapat, A. P. (2013) · Advances in Dairy Research · doi:10.4172/2329-888x.1000107 · Cited by 219
Glucan synthesis in the genus Lactobacillus: isolation and characterization of glucansucrase genes, enzymes and glucan products from six different strains
Kralj, S., van Geel-Schutten, G. H., Dondorff, M. M. G., Kirsanovs, S., van der Maarel, M. J. E. C., & Dijkhuizen, L. (2004) · Microbiology · doi:10.1099/mic.0.27321-0 · Cited by 213
Factors Affecting Exocellular Polysaccharide Production by Lactobacillus delbrueckii subsp.bulgaricus Grown in a Chemically Defined Medium
Petry, S., Furlan, S., Crepeau, M.-J., Cerning, J., & Desmazeaud, M. (2000) · Applied and Environmental Microbiology · doi:10.1128/aem.66.8.3427-3431.2000 · Cited by 209
Production and Structural Characterization of Exopolysaccharides from Newly Isolated Probiotic Lactic Acid Bacteria
Abid, Y., Casillo, A., Gharsallah, H., Joulak, I., Lanzetta, R., Corsaro, M. M., Attia, H., & Azabou, S. (2018) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2017.10.155 · Cited by 208
Phosphate group requirement for mitogenic activation of lymphocytes by an extracellular phosphopolysaccharide from Lactobacillus delbrueckii ssp. bulgaricus
Kitazawa, H., Harata, T., Uemura, J., Saito, T., Kaneko, T., & Itoh, T. (1998) · International Journal of Food Microbiology · doi:10.1016/s0168-1605(98)00030-0 · Cited by 205
Characterization and bioactivities of the exopolysaccharide from a probiotic strain of Lactobacillus plantarum WLPL04
Liu, Z., Zhang, Z., Qiu, L., Zhang, F., Xu, X., Wei, H., & Tao, X. (2017) · Journal of Dairy Science · doi:10.3168/jds.2016-11944 · Cited by 205
Biopolymers from Lactic Acid Bacteria. Novel Applications in Foods and Beverages
Torino, M. I., Font de Valdez, G., & Mozzi, F. (2015) · Frontiers in Microbiology · doi:10.3389/fmicb.2015.00834 · Cited by 201
NMR spectroscopic analysis of exopolysaccharides produced by Leuconostoc citreum and Weissella confusa
Maina, N. H., Tenkanen, M., Maaheimo, H., Juvonen, R., & Virkki, L. (2008) · Carbohydrate Research · doi:10.1016/j.carres.2008.04.012 · Cited by 200
Characterization and Antibacterial Activity of a Novel Exopolysaccharide Produced by Lactobacillus kefiranofaciens DN1 Isolated from Kefir
Jeong, D., Kim, D.-H., Kang, I.-B., Kim, H., Song, K.-Y., Kim, H.-S., & Seo, K.-H. (2017) · Food Control · doi:10.1016/j.foodcont.2017.02.033 · Cited by 198
Immune Modulation Capability of Exopolysaccharides Synthesised by Lactic Acid Bacteria and Bifidobacteria
Hidalgo-Cantabrana, C., López, P., Gueimonde, M., Reyes‐Gavilán, C. G. D. L., Suárez, A., Margollés, A., & Ruas‐Madiedo, P. (2012) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-012-9110-2 · Cited by 197
Lactic Acid Bacteria Exopolysaccharides Producers: A Sustainable Tool for Functional Foods
Prete, R., Alam, M. K., Perpetuini, G., Perla, C., Pittia, P., & Corsetti, A. (2021) · Foods · doi:10.3390/foods10071653 · Cited by 194 · cited 1×
“For a more objective test, ruthenium red staining is used in milk agar plates and produces red colonies of non-ropy EPS producers, while ropy colonies remain white [112].”
Background
Physiological function of exopolysaccharides produced by Lactococcus lactis
Looijesteijn, P. J., Trapet, L., de Vries, E., Abee, T., & Hugenholtz, J. (2001) · International Journal of Food Microbiology · doi:10.1016/s0168-1605(00)00437-2 · Cited by 194
Lactic acid bacteria as sensory biomodulators for fermented cereal-based beverages
Peyer, L. C., Zannini, E., & Arendt, E. K. (2016) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2016.05.009 · Cited by 181
Characterization of Exopolysaccharide Produced byStreptococcus thermophilusCC30
Kanamarlapudi, S. L. R. K., & Muddada, S. (2017) · BioMed Research International · doi:10.1155/2017/4201809 · Cited by 180
The anti-cancer effects and mechanisms of lactic acid bacteria exopolysaccharides in vitro: A review
Wu, J., Zhang, Y., Ye, L., & Wang, C. (2020) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2020.117308 · Cited by 178
Effects of pH, Temperature, Supplementation with Whey Protein Concentrate, and Adjunct Cultures on the Production of Exopolysaccharides by Streptococcus thermophilus 1275
Zisu, B., & Shah, N. P. (2003) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(03)73944-7 · Cited by 175
Structural Characterization and Biological Activities of an Exopolysaccharide Kefiran Produced by Lactobacillus kefiranofaciens WT-2BT
Maeda, H., Xia Shuang, Z. H. U., Suzuki, S., Suzuki, K., & Kitamura, S. (2004) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf049617g · Cited by 171
Cholesterol Lowering Activity of Ropy Fermented Milk
NAKAJIMA, H., SUZUKI, Y., & HIROTA, T. (1992) · Journal of Food Science · doi:10.1111/j.1365-2621.1992.tb06848.x · Cited by 170
Biomedical Applications of Bacterial Exopolysaccharides: A Review
Nadzir, M. M., Nurhayati, R. W., Idris, F. N., & Nguyen, M. H. (2021) · Polymers · doi:10.3390/polym13040530 · Cited by 170
Immunomodulatory Effects of Polysaccharides Produced by Lactobacillus delbrueckii ssp. bulgaricus OLL1073R-1
Makino, S., Ikegami, S., Kano, H., Sashihara, T., Sugano, H., Horiuchi, H., Saito, T. T., & Oda, M. (2006) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(06)72560-7 · Cited by 169
Effects of carboxymethyl cellulose (CMC) and microcrystalline cellulose (MCC) as fat replacers on the microstructure and sensory characteristics of fried beef patties
Gibis, M., Schuh, V., & Weiß, J. (2014) · Food Hydrocolloids · doi:10.1016/j.foodhyd.2014.11.021 · Cited by 168
Characterization, Bioactivities, and Rheological Properties of Exopolysaccharide Produced by Novel Probiotic Lactobacillus plantarum C70 Isolated from Camel Milk
Ayyash, M., Abu-Jdayil, B., Itsaranuwat, P., Galiwango, E., Tamiello-Rosa, C., Abdullah, H., Esposito, G., Hunashal, Y., Obaid, R. S., & Hamed, F. (2020) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2019.09.171 · Cited by 167
Characterization of a novel exopolysaccharide produced by Lactobacillus gasseri FR4 and demonstration of its in vitro biological properties
Rani, R. P., Anandharaj, M., & Ravindran, A. D. (2017) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2017.11.062 · Cited by 164
The levansucrase and inulosucrase enzymes of Lactobacillus reuteri 121 catalyse processive and non-processive transglycosylation reactions
Ozimek, L. K., Kralj, S., van der Maarel, M. J. E. C., & Dijkhuizen, L. (2006) · Microbiology · doi:10.1099/mic.0.28484-0 · Cited by 163
Antioxidant and antiproliferative potential of biosurfactants isolated from Lactobacillus casei and their anti-biofilm effect in oral Staphylococcus aureus strains
Merghni, A., Dallel, I., Noumi, E., Kadmi, Y., Hentati, H. A. A., Tobji, S., Amor, A. B., & Mastouri, M. (2017) · Microbial Pathogenesis · doi:10.1016/j.micpath.2017.01.017 · Cited by 162
Characterization of a novel galactan produced by Weissella confusa KR780676 from an acidic fermented food
Kavitake, D., Devi, P. B., Singh, S. P., & Shetty, P. H. (2016) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2016.01.099 · Cited by 160
Exopolysaccharides production by Lactobacillus acidophilus LA5 and Bifidobacterium animalis subsp. lactis BB12: Optimization of fermentation variables and characterization of structure and bioactivities
Amiri, S., Mokarram, R. R., Khiabani, M. S., Bari, M. R., & Alizadeh, M. (2018) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2018.11.084 · Cited by 160
Benefits of bacteria-derived exopolysaccharides on gastrointestinal microbiota, immunity and health
Oerlemans, M. M. P., Akkerman, R., Ferrari, M. D. L., Walvoort, M. T. C., & de Vos, P. (2020) · Journal of Functional Foods · doi:10.1016/j.jff.2020.104289 · Cited by 159
Bacterial exopolysaccharides for improvement of technological, functional and rheological properties of yoghurt
Tiwari, S., Kavitake, D., Devi, P. B., & Shetty, P. H. (2021) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2021.05.140 · Cited by 159
Production of exopolysaccharides by Lactobacillus helveticus MB2-1 and its functional characteristics in vitro
Li, W., Ji, J., Rui, X., Yu, J., Tang, W., Chen, X., Jiang, M., & Dong, M. (2014) · LWT · doi:10.1016/j.lwt.2014.06.063 · Cited by 157
Characterization and Immunomodulatory Activity of an Exopolysaccharide Produced by Lactobacillus plantarum JLK0142 Isolated from Fermented Dairy Tofu
Wang, J., Wu, T., Fang, X., Min, W., & Yang, Z. (2018) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2018.04.099 · Cited by 155
Blends and composites of exopolysaccharides; properties and applications: A review
Hussain, A., Zia, K. M., Tabasum, S., Noreen, A., Ali, M., Iqbal, R., & Zuber, M. (2016) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2016.09.104 · Cited by 154
A Novel Rhamnose-Rich Hetero-exopolysaccharide Isolated from Lactobacillus paracasei DG Activates THP-1 Human Monocytic Cells
Balzaretti, S., Taverniti, V., Guglielmetti, S., Fiore, W., Minuzzo, M., Ngehnyuiy, N. H., Ngere, J. B., Sadiq, S., Humphreys, P. N., & Laws, A. P. (2016) · Applied and Environmental Microbiology · doi:10.1128/aem.02702-16 · Cited by 154
Effects of oral administration of yogurt fermented with Lactobacillus delbrueckii ssp. bulgaricus OLL1073R-1 and its exopolysaccharides against influenza virus infection in mice
Nagai, T., Makino, S., Ikegami, S., Itoh, H., & Yamada, H. (2011) · International Immunopharmacology · doi:10.1016/j.intimp.2011.09.012 · Cited by 151
Use of Selected Lactic Acid Bacteria and Quinoa Flour for Manufacturing Novel Yogurt-Like Beverages
Lorusso, A., Coda, R., Montemurro, M., & Rizzello, C. G. (2018) · Foods · doi:10.3390/foods7040051 · Cited by 151
Improvement of the Texture of Yogurt by Use of Exopolysaccharide Producing Lactic Acid Bacteria
Han, X., Yang, Z., Jing, X., Yu, P., Zhang, Y., Yi, H., & Zhang, L. (2016) · BioMed Research International · doi:10.1155/2016/7945675 · Cited by 150
Influence of κ-carrageenan on the thermal gelation of salt-soluble meat proteins
Verbeken, D., Neirinck, N., der Meeren, P. V., & Dewettinck, K. (2005) · Meat Science · doi:10.1016/j.meatsci.2004.12.007 · Cited by 148
Production, characterization and In vitro antioxidant activities of exopolysaccharide from Weissella cibaria GA44
Adesulu-Dahunsi, A. T., Sanni, A. I., & Jeyaram, K. (2017) · LWT · doi:10.1016/j.lwt.2017.09.013 · Cited by 146
Diversity of Heteropolysaccharide-Producing Lactic Acid Bacterium Strains and Their Biopolymers
Mozzi, F., Vaningelgem, F., Hebert, E. M., der Meulen, R. V., Foulquié-Moreno, M. R., de Valdez, G. F., & Vuyst, L. D. (2006) · Applied and Environmental Microbiology · doi:10.1128/aem.02780-05 · Cited by 145
Development of novel quinoa-based yoghurt fermented with dextran producer Weissella cibaria MG1
Zannini, E., Jeske, S., Lynch, K. M., & Arendt, E. K. (2018) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2018.01.001 · Cited by 142
Exopolysaccharides from lactic acid bacteria: Structural analysis, molecular weight effect on immunomodulation
Surayot, U., Wang, J., Seesuriyachan, P., Kuntiya, A., Tabarsa, M., Lee, Y., Kim, J., Park, W., & You, S. (2014) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2014.05.005 · Cited by 141
Characterization and antioxidant activity of an acidic exopolysaccharide from Lactobacillus plantarum JLAU103
Min, W., Fang, X., Wu, T., Li, F., Liu, C., & Wang, J. (2018) · Journal of Bioscience and Bioengineering · doi:10.1016/j.jbiosc.2018.12.004 · Cited by 141
Structural Characterization and Anticancer Activity of Cell-Bound Exopolysaccharide from Lactobacillus helveticus MB2-1
Li, W., Xia, X., Tang, W., Ji, J., Rui, X., Chen, X., Jiang, M., Zhou, J., Zhang, Q., & Dong, M. (2015) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.5b01086 · Cited by 140
Kefiran, a branched polysaccharide: Preparation, properties and applications: A review
Moradi, Z., & Kalanpour, N. (2019) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2019.115100 · Cited by 140
Sugar reduction in bakery products: Current strategies and sourdough technology as a potential novel approach
Sahin, A. W., Zannini, E., Coffey, A., & Arendt, E. K. (2019) · Food Research International · doi:10.1016/j.foodres.2019.108583 · Cited by 137
Microbial exopolysaccharides for immune enhancement: Fermentation, modifications and bioactivities
Chaisuwan, W., Jantanasakulwong, K., Wangtueai, S., Phimolsiripol, Y., Chaiyaso, T., Techapun, C., Phongthai, S., You, S., Regenstein, J. M., & Seesuriyachan, P. (2020) · Food Bioscience · doi:10.1016/j.fbio.2020.100564 · Cited by 137
Exopolysaccharide-producing Streptococcus thermophilus strains as functional starter cultures in the production of fermented milks
Vuyst, L. D., Zamfir, M., Mozzi, F., Adriany, T., Marshall, V. M., Degeest, B., & Vaningelgem, F. (2003) · International Dairy Journal · doi:10.1016/s0958-6946(03)00105-5 · Cited by 135
Impact of growth temperature on exopolysaccharide production and probiotic properties of Lactobacillus paracasei strains isolated from kefir grains
Bengoa, A. A., Llamas, M. G., Iraporda, C., Dueñas, M. T., Abraham, A. G., & Garrote, G. L. (2017) · Food Microbiology · doi:10.1016/j.fm.2017.08.012 · Cited by 132
Evaluation of Dermal Wound Healing Activity and in Vitro Antibacterial and Antioxidant Activities of a New Exopolysaccharide Produced by Lactobacillus sp.Ca6
Trabelsi, I., Ktari, N., Ben Slima, S., Triki, M., Bardaa, S., Mnif, H., & Ben Salah, R. (2017) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2017.05.017 · Cited by 128
Purification, characterization and antioxidant activity of dextran produced by Leuconostoc pseudomesenteroides from homemade wine
Du, R., Qiao, X., Zhao, F., Song, Q., Zhou, Q., Wang, Y., Pan, L., Han, Y., & Zhou, Z. (2018) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2018.06.116 · Cited by 127
Mechanisms in The Glucansucrase Synthesis of Polysaccharides and Oligosaccharides From Sucrose
Robyt, J. F. (1995) · Advances in carbohydrate chemistry and biochemistry · doi:10.1016/s0065-2318(08)60193-6 · Cited by 126
Exopolysaccharides of Lactobacillus reuteri: Their Influence on Adherence of E. Coli to Epithelial Cells and Inflammatory Response
Kšonžeková, P., Bystrický, P., Vlčková, S., Pätoprstý, V., Pulzová, L., Mudroňová, D., Kubašková, T., Csank, T., & Tkáčiková, Ľ. (2016) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2015.12.037 · Cited by 122
Structural analysis of the α-d-glucan (EPS180) produced by the Lactobacillus reuteri strain 180 glucansucrase GTF180 enzyme
van Leeuwen, S. S., Kralj, S., van Geel-Schutten, I. H., Gerwig, G. J., Dijkhuizen, L., & Kamerling, J. P. (2008) · Carbohydrate Research · doi:10.1016/j.carres.2008.01.042 · Cited by 121
Structure/function relationship of homopolysaccharide producing glycansucrases and therapeutic potential of their synthesised glycans
Korakli, M., & Vogel, R. F. (2006) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-006-0469-4 · Cited by 121
Glucansucrases: mechanism of action and structure–function relationships
Monchois, V. (1999) · FEMS Microbiology Reviews · doi:10.1016/s0168-6445(98)00041-2 · Cited by 121
Influence of lupin-based milk alternative heat treatment and exopolysaccharide-producing lactic acid bacteria on the physical characteristics of lupin-based yogurt alternatives
Hickisch, A., Beer, R., Vogel, R. F., & Toelstede, S. (2016) · Food Research International · doi:10.1016/j.foodres.2016.03.037 · Cited by 119
Monosaccharide composition influence and immunomodulatory effects of probiotic exopolysaccharides
Chen, Y.-C., Wu, Y., & Hu, C. (2019) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2019.04.109 · Cited by 119
Exopolysaccharide Production and Texture-Promoting Abilities of Mixed-Strain Starter Cultures in Yogurt Production
Bouzar, F., Cerning, J., & Desmazeaud, M. (1997) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(97)76181-2 · Cited by 117
Characterization, high production and antimicrobial activity of exopolysaccharides from Lactococcus lactis F-mou
Nehal, F., Sahnoun, M., Smaoui, S., Jaouadi, B., Béjar, S., & Sebaihia, M. (2019) · Microbial Pathogenesis · doi:10.1016/j.micpath.2019.04.018 · Cited by 116
Development of Low-Fat/Reduced-Fat Processed Meat Products using Fat Replacers and Analogues
Kumar, Y. (2019) · Food Reviews International · doi:10.1080/87559129.2019.1704001 · Cited by 115
Antiproliferative and anticytotoxic effects of cell fractions and exopolysaccharides from Lactobacillus casei 01
Liu, C., Chu, F.-J., Chou, C., & Yu, R. (2011) · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · doi:10.1016/j.mrgentox.2011.01.005 · Cited by 114
Naturally occurring 2-substituted (1,3)-β-d-glucan producing Lactobacillus suebicus and Pediococcus parvulus strains with potential utility in the production of functional foods
Garai‐Ibabe, G., Dueñas, M. T., Irastorza, A., Sierra‐Filardi, E., Werning, M. L., López, P., Corbí, A. L., & de Palencia, P. F. (2010) · Bioresource Technology · doi:10.1016/j.biortech.2010.07.050 · Cited by 110
Hypocholesterolemic and bioactive potential of exopolysaccharide from a probiotic Enterococcus faecium K1 isolated from kalarei
Bhat, B., & Bajaj, B. K. (2018) · Bioresource Technology · doi:10.1016/j.biortech.2018.01.078 · Cited by 110
Biotechnological potential of novel glycoside hydrolase family 70 enzymes synthesizing α-glucans from starch and sucrose
Gangoiti, J., Pijning, T., & Dijkhuizen, L. (2017) · Biotechnology Advances · doi:10.1016/j.biotechadv.2017.11.001 · Cited by 109
Partial characterization and antioxidant activity of exopolysaccharides produced by Lactobacillus plantarum CNPC003
Bomfim, V. B., Neto, J. H. P. L., Leite, K. S., Vieira, É. D. A., Iacomini, M., Silva, C. M., dos Santos, K. M. O., & Cardarelli, H. R. (2020) · LWT · doi:10.1016/j.lwt.2020.109349 · Cited by 103
Self-citation
Characterisation of a novel water-soluble polysaccharide from Leuconostoc citreum SK24.002
Miao, M., Bai, A., Jiang, B., Song, Y., Cui, S. W., & Zhang, T. (2013) · Food Hydrocolloids · doi:10.1016/j.foodhyd.2013.10.014 · Cited by 102
A review of nondairy kefir products: their characteristics and potential human health benefits
Egea, M. B., dos Santos, D. C., Filho, J. G. D. O., Ores, J. D. C., Takeuchi, K. P., & Lemes, A. C. (2020) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2020.1844140 · Cited by 102
Highly Hydrolytic Reuteransucrase from Probiotic Lactobacillus reuteri Strain ATCC 55730
Kralj, S., Stripling, E., Sanders, P., van Geel-Schutten, G. H., & Dijkhuizen, L. (2005) · Applied and Environmental Microbiology · doi:10.1128/aem.71.7.3942-3950.2005 · Cited by 101
Lactobacillus-produced exopolysaccharides and their potential health benefits: A review
Patten, D. A., & Laws, A. P. (2015) · Beneficial Microbes · doi:10.3920/bm2014.0117 · Cited by 100
Isolation, purification, characterization and immunostimulatory activity of an exopolysaccharide produced by Lactobacillus pentosus LZ-R-17 isolated from Tibetan kefir
You, X., Yang, L., Zhao, X., Ma, K., Chen, X., Zhang, C., Wang, G., Dong, M., Rui, X., Zhang, Q., et al. (2020) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2020.05.027 · Cited by 98
Role of the gut microbiota in the pathogenesis of coeliac disease and potential therapeutic implications
Akobeng, A. K., Singh, P., Kumar, M., & Khodor, S. A. (2020) · European Journal of Nutrition · doi:10.1007/s00394-020-02324-y · Cited by 96
The effect of whey protein concentrates and hydrocolloids on the texture and colour characteristics of chicken sausages
Andrés, S. C., Zaritzky, N., & Califano, A. N. (2006) · International Journal of Food Science & Technology · doi:10.1111/j.1365-2621.2005.01152.x · Cited by 95
Use of an exopolysaccharide-based edible coating and lactic acid bacteria with antifungal activity to preserve the postharvest quality of cherry tomato
Álvarez, A., Manjarres, J. J., Ramírez‐Toro, C., & Bolívar, G. (2021) · LWT · doi:10.1016/j.lwt.2021.112225 · Cited by 94
Exopolysaccharide (EPS) Biosynthesis by Lactobacillus sakei 0-1: Production Kinetics, Enzyme Activities and EPS Yields
Degeest, B., Janssens, B., & De Vuyst, L. (2001) · Journal of Applied Microbiology · doi:10.1046/j.1365-2672.2001.01404.x · Cited by 93
Preparation, Partial Characterization and Bioactivity of Exopolysaccharides from Lactobacillus casei LC2W
Ai, L., Zhang, H., Guo, B., Chen, W., Wu, Z., & Wu, Y. (2008) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2008.03.004 · Cited by 93
Exopolysaccharides produced byLactobacillussp.: Biosynthesis and applications
Oleksy, M., & Klewicka, E. (2016) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2016.1187112 · Cited by 93
Sequence analysis of the gene encoding alternansucrase, a sucrose glucosyltransferase from Leuconostoc mesenteroides NRRL B-1355
Arguello-Morales, M., Remaud‐Siméon, M., Pizzut‐Serin, S., Sarçabal, P., Willemot, R., & MONSAN, P. F. (2000) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.2000.tb08878.x · Cited by 92
Structural investigation and response surface optimisation for improvement of kefiran production yield from a low-cost culture medium
Ghasemlou, M., Khodaiyan, F., Jahanbin, K., Gharibzahedi, S. M. T., & Taheri, S. (2012) · Food Chemistry · doi:10.1016/j.foodchem.2012.01.046 · Cited by 90
Exopolysaccharides Produced by Leuconostoc mesenteroides Strain NTM048 as an Immunostimulant To Enhance the Mucosal Barrier and Influence the Systemic Immune Response
Matsuzaki, C., Hayakawa, A., Matsumoto, K., Katoh, T., Yamamoto, K., & Hisa, K. (2015) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.5b01960 · Cited by 89
Microbial Exopolysaccharides: Biosynthesis and Potential Applications
Madhuri, K. V., & Prabhakar, K. (2014) · Oriental Journal Of Chemistry · doi:10.13005/ojc/300362 · Cited by 89
Gel formation and rheological properties of fermented milk with in situ exopolysaccharide production by lactic acid bacteria
Gentès, M., St‐Gelais, D., & Turgeon, S. L. (2011) · Dairy Science and Technology · doi:10.1007/s13594-011-0039-0 · Cited by 89
Role of the Two Catalytic Domains of DSR-E Dextransucrase and Their Involvement in the Formation of Highly α-1,2 Branched Dextran
Fabre, É., Bozonnet, S., Arcache, A., Willemot, R., Vignon, M. R., MONSAN, P. F., & Remaud‐Siméon, M. (2004) · Journal of Bacteriology · doi:10.1128/jb.187.1.296-303.2005 · Cited by 88
Lactobacillus satsumensis sp. nov., isolated from mashes of shochu, a traditional Japanese distilled spirit made from fermented rice and other starchy materials
Endo, A., & Okada, S. (2005) · INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY · doi:10.1099/ijs.0.63248-0 · Cited by 85
Effect of Exopolysaccharide Produced by Isogenic Strains of Lactococcus lactis on Half-Fat Cheddar Cheese
Costa, N. E., Hannon, J. A., Guinee, T. P., Auty, M. A. E., McSweeney, P. L. H., & Beresford, T. P. (2010) · Journal of Dairy Science · doi:10.3168/jds.2009-3008 · Cited by 85
In vitro and in vivo evaluation of xanthan gum–succinic anhydride hydrogels for the ionic strength-sensitive release of antibacterial agents
Wang, B., Han, Y., Lin, Q., Liu, H., Shen, C., Nan, K., & Chen, H. (2016) · Journal of Materials Chemistry B · doi:10.1039/c5tb02046h · Cited by 85
Exopolysaccharides and Antimicrobial Biosurfactants Produced by Paenibacillus macerans TKU029
Liang, T., Wu, C., Cheng, W.-T., Chen, Y., Wang, C.-L., Wang, I.-L., & Wang, S. (2013) · Applied Biochemistry and Biotechnology · doi:10.1007/s12010-013-0568-5 · Cited by 84
Use of exopolysaccharide-producing cultures to improve the functionality of low fat cheese
Broadbent, J. R., McMahon, D. J., Oberg, C. J., & Welker, D. L. (2001) · International Dairy Journal · doi:10.1016/s0958-6946(01)00084-x · Cited by 83
Exopolysaccharide Produced by Streptococcus thermophiles S-3: Molecular, Partial Structural and Rheological Properties
Xu, Z., Guo, Q., Zhang, H., Wu, Y., Hang, X., & Ai, L. (2018) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2018.04.014 · Cited by 79
Microbial Exopolysaccharides
Mishra, A., & Jha, B. (2013) · Springer eBooks · doi:10.1007/978-3-642-31331-8_25 · Cited by 78
Exopolysaccharides of Lactic Acid Bacteria for Food and Colon Health Applications
TSUDA, H. (2013) · InTech eBooks · doi:10.5772/50839 · Cited by 76
Lactic acid bacteria-derived α-glucans: From enzymatic synthesis to miscellaneous applications
Chen, Z., Ni, D., Zhang, W., Stressler, T., & Mu, W. (2021) · Biotechnology Advances · doi:10.1016/j.biotechadv.2021.107708 · Cited by 74
Immunostimulatory activity of exopolysaccharides from probiotic Lactobacillus casei WXD030 strain as a novel adjuvant in vitro and in vivo
Xiu, L., Zhang, H. C., Hu, Z., Liang, Y., Guo, S., Yang, M. H., Du, R., & Wang, X. (2018) · Food and Agricultural Immunology · doi:10.1080/09540105.2018.1513994 · Cited by 73
Exopolysaccharide-producing Bifidobacterium animalis subsp. lactis strains and their polymers elicit different responses on immune cells from blood and gut associated lymphoid tissue
Hidalgo-Cantabrana, C., Nikolić, M., López, P., Suárez, A., Miljković, M., Kojić, M., Margollés, A., Golić, N., & Ruas‐Madiedo, P. (2014) · Anaerobe · doi:10.1016/j.anaerobe.2014.01.003 · Cited by 72
Selection of EPS-producing Lactobacillus strains isolated from kefir grains and rheological characterization of the fermented milks
Hamet, M. F., Piermaría, J., & Abraham, A. G. (2015) · LWT · doi:10.1016/j.lwt.2015.03.097 · Cited by 72
Optimization of Media Composition to Maximize the Yield of Exopolysaccharides Production by Lactobacillus rhamnosus Strains
Oleksy, M., & Klewicka, E. (2019) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-019-09581-2 · Cited by 72
Exopolysaccharides production by Lactobacillus rhamnosus strains – Optimization of synthesis and extraction conditions
Oleksy, M., Klewicka, E., & Piekarska-Radzik, L. (2020) · LWT · doi:10.1016/j.lwt.2020.109055 · Cited by 72
Effects of kefir grains from different origins on proteolysis and volatile profile of goat milk kefir
Wang, H., Sun, X., Song, X., & Guo, M. (2020) · Food Chemistry · doi:10.1016/j.foodchem.2020.128099 · Cited by 71
Effect of galactose and glucose on the exopolysaccharide production and the activities of biosynthetic enzymes in Lactobacillus casei CRL 87
Mozzi, F., Rollán, G., de Giori, G. S., & de Valdez, G. F. (2001) · Journal of Applied Microbiology · doi:10.1046/j.1365-2672.2001.01367.x · Cited by 70
Characterization of glucan-producing Leuconostoc strains isolated from sourdough
Bounaix, M.-S., Gabriel, V., Robert, H., Morel, S., Remaud‐Siméon, M., Gabriel, B., & Fontagné‐Faucher, C. (2010) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2010.05.026 · Cited by 68
Lactobacillus nagelii sp. nov., an organism isolated from a partially fermented wine.
Edwards, C. G., Collins, M., Lawson, P. A., & Rodriguez, A. V. (2000) · INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY · doi:10.1099/00207713-50-2-699 · Cited by 67
Cloning, expression, and characterization of an insoluble glucan-producing glucansucrase from Leuconostoc mesenteroides NRRL B-1118
Côté, G. L., & Skory, C. D. (2011) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-011-3562-2 · Cited by 66
Purification, partial structural characterization and health benefits of exopolysaccharides from potential probiotic Pediococcus acidilactici NCDC 252
Kumar, R., Bansal, P., Singh, J., & Dhanda, S. (2020) · Process Biochemistry · doi:10.1016/j.procbio.2020.08.028 · Cited by 66
Glycosidic bond specificity of glucansucrases: on the role of acceptor substrate binding residues
Leemhuis, H., Pijning, T., Dobruchowska, J. M., Dijkstra, B. W., & Dijkhuizen, L. (2012) · Biocatalysis and Biotransformation · doi:10.3109/10242422.2012.676301 · Cited by 65
Chemical Signals and Mechanosensing in Bacterial Responses to Their Environment
Harapanahalli, A. K., Younes, J. A., Allan, E., van der Mei, H. C., & Busscher, H. J. (2015) · PLoS Pathogens · doi:10.1371/journal.ppat.1005057 · Cited by 64
Structural and immunochemical studies of neutral exopolysaccharide produced by Lactobacillus johnsonii 142
Górska, S., Jachymek, W., Rybka, J., Strus, M., Heczko, P. B., & Gamian, A. (2009) · Carbohydrate Research · doi:10.1016/j.carres.2009.09.015 · Cited by 64
Expression of Streptococcus mutans gtf genes in Streptococcus milleri
Fukushima, K., Ikeda, T., & Kuramitsu, H. K. (1992) · Infection and Immunity · doi:10.1128/iai.60.7.2815-2822.1992 · Cited by 64
Rheological and emulsifying properties of an exopolysaccharide produced by potential probiotic Leuconostoc citreum-BMS strain
Abid, Y., Azabou, S., Blecker, C. S., Gharsallaoui, A., Corsaro, M. M., Besbes, S., & Attia, H. (2020) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2020.117523 · Cited by 64
Exposition of antitumour activity of a chemically characterized exopolysaccharide from a probiotic Lactobacillus plantarum MTCC 9510
Ismail, B., & Nampoothiri, K. M. (2013) · Biologia · doi:10.2478/s11756-013-0275-2 · Cited by 63
Molecular characterization and expression analysis of the glucansucrase DSRWC fromWeissella cibariasynthesizing a α(1→6) glucan
Kang, H., Oh, J., & Kim, D. (2009) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.2008.01460.x · Cited by 63
Comparison of the Functionality of Exopolysaccharides Produced by Sourdough Lactic Acid Bacteria in Bread and Steamed Bread
Xu, D., Hu, Y., Wu, F., Jin, Y., Xu, X., & Gänzle, M. G. (2020) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.0c02703 · Cited by 63
Preparation screening, production optimization and characterization of exopolysaccharides produced by Lactobacillus sanfranciscensis Ls-1001 isolated from Chinese traditional sourdough
Zhang, G., Zhang, W., Sun, L., Sadiq, F. A., Yang, Y., Gao, J., & Sang, Y. (2019) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2019.08.077 · Cited by 62
A Review on Production of Exopolysaccharide and Biofilm in Probiotics Like Lactobacilli and Methods of Analysis
(2020) · Biointerface Research in Applied Chemistry · doi:10.33263/briac105.60586075 · Cited by 62
Four glucosyltransferases, GtfJ, GtfK, GtfL and GtfM, from Streptococcus salivarius ATCC 25975
Simpson, C. L., Cheetham, N. W. H., & Jacques, N. A. (1995) · Microbiology · doi:10.1099/13500872-141-6-1451 · Cited by 61
In vivo assessment of possible probiotic properties of Bacillus subtilis and prebiotic properties of levan
Hamdy, A. A., Elattal, N. A., Amin, M. A., Ali, A. E., Mansour, N. M., Awad, G. E. A., Farrag, A. R. H., & Esawy, M. A. (2017) · Biocatalysis and Agricultural Biotechnology · doi:10.1016/j.bcab.2017.12.001 · Cited by 61
Techno-Functional Role of Exopolysaccharides in Cereal-Based, Yogurt-Like Beverages
Ripari, V. (2019) · Beverages · doi:10.3390/beverages5010016 · Cited by 61
Effects of carbohydrate source on physicochemical properties of the exopolysaccharide produced by Lactobacillus fermentum TDS030603 in a chemically defined medium
Fukuda, K., Shi, T., Nagami, K., Leo, F., Nakamura, T., Yasuda, K., Senda, A., Motoshima, H., & Urashima, T. (2009) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2009.10.037 · Cited by 59
Structural and physicochemical characterisation and antioxidant activity of an α-D-glucan produced by sourdough isolate Weissella cibaria MED17
Aburas, H. M., İspirli, H., Taylan, O., Yılmaz, M. T., & Dertli̇, E. (2020) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2020.06.030 · Cited by 59
Deoxycholic acid modified-carboxymethyl curdlan conjugate as a novel carrier of epirubicin: In vitro and in vivo studies
Gao, F., Li, L., Zhang, H., Yang, W., Chen, H., Zhou, J., Zhou, Z., Wang, Y., Cai, Y., Li, X., et al. (2010) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2010.03.044 · Cited by 58
Use of Lactobacillus mucosae DPC 6426, an exopolysaccharide-producing strain, positively influences the techno-functional properties of yoghurt
London, L. E. E., Chaurin, V., Auty, M. A. E., Fenelon, M. A., Fitzgerald, G. F., Ross, R. P., & Stanton, C. (2014) · International Dairy Journal · doi:10.1016/j.idairyj.2014.08.011 · Cited by 58
Optimization of anticancer exopolysaccharide production from probiotic Lactobacillus acidophilus by response surface methodology
Deepak, V., Pandian, S. R. K., Sivasubramaniam, S. D., Hariharan, N., & Sundar, K. (2015) · Preparative Biochemistry & Biotechnology · doi:10.1080/10826068.2015.1031386 · Cited by 58
Characterization of a yogurt-quality improving exopolysaccharide from Streptococcus thermophilus AR333
Zhang, H., Ren, W., Guo, Q., Xiong, Z., Wang, G., Xia, Y., Lai, P. F. H., Yin, B., & Ai, L. (2017) · Food Hydrocolloids · doi:10.1016/j.foodhyd.2017.12.017 · Cited by 57
Exopolysaccharides in sourdough fermented by Weissella confusa QS813 protected protein matrix and quality of frozen gluten-red bean dough during freeze-thaw cycles
Zhang, B., Omedi, J. O., Zheng, J., Huang, W., Jia, C., Zhou, L., Zou, Q., Li, N., & Gao, T. (2021) · Food Bioscience · doi:10.1016/j.fbio.2021.101180 · Cited by 57
Molecular characterization and expression analysis of the dextransucrase DsrD of Leuconostoc mesenteroides Lcc4 in homologous and heterologous Lactococcus lactis cultures
Neubauer, H., Bauché, A., & Mollet, B. (2003) · Microbiology · doi:10.1099/mic.0.26029-0 · Cited by 56
Bioactive exopolysaccharides from a S. thermophilus strain: Screening, purification and characterization
Ren, W., Xia, Y., Wang, G., Zhang, H., Zhu, S., & Ai, L. (2016) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2016.01.085 · Cited by 55
Effects of in situ exopolysaccharide production and fermentation conditions on physicochemical, microbiological, textural and microstructural properties of Turkish-type fermented sausage (sucuk)
Dertli̇, E., Yılmaz, M. T., Tatlısu, N. B., Toker, Ö. S., Cankurt, H., & Sağdıç, O. (2016) · Meat Science · doi:10.1016/j.meatsci.2016.06.008 · Cited by 54
Impact of in situ formed exopolysaccharides on dough performance and quality of Chinese steamed bread
Tang, X., Liu, R., Huang, W., Zhang, B., Wu, Y., Zhuang, J., Omedi, J. O., Wang, F., & Zheng, J. (2018) · LWT · doi:10.1016/j.lwt.2018.04.039 · Cited by 53
’Ropy’ Phenotype, Exopolysaccharides and Metabolism: Study on Food Isolated Potential Probiotics LAB
Cirrincione, S., Breuer, Y., Mangiapane, E., Mazzoli, R., & Pessione, E. (2018) · Microbiological Research · doi:10.1016/j.micres.2018.07.004 · Cited by 53
Evaluation of antioxidant, antibacterial and cytotoxicity activities of exopolysaccharide from Enterococcus strains isolated from traditional Iranian Kishk
Vosough, P. R., Najafi, M. B. H., Dovom, M. R. E., Javadmanesh, A., & Mayo, B. (2021) · Journal of Food Measurement & Characterization · doi:10.1007/s11694-021-01092-5 · Cited by 53
Characterisation of a new exopolysaccharide obtained from of fermented kefir grains in soymilk
Botelho, P. D. S., Maciel, M. I. S., Bueno, L. A., Marques, M. D. F. F., Marques, D. N., & Silva, T. M. S. (2014) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2014.02.036 · Cited by 52
Purification and characterization of dextran produced by Leuconostoc pseudomesenteroides PC as a potential exopolysaccharide suitable for food applications
Wang, B., Song, Q., Zhao, F., Xiao, H., Zhou, Z., & Han, Y. H. (2019) · Process Biochemistry · doi:10.1016/j.procbio.2019.08.020 · Cited by 52
In vitro prebiotic activities of exopolysaccharide from Leuconostoc pseudomesenteroides XG5 and its effect on the gut microbiota of mice
Pan, L., Han, Y., & Zhou, Z. (2020) · Journal of Functional Foods · doi:10.1016/j.jff.2020.103853 · Cited by 52
Growth and exopolysaccharide production during free and immobilized cell chemostat culture of Lactobacillus rhamnosus RW-9595M
Bergmaier, D., Champagne, C. P., & Lacroix, C. (2005) · Journal of Applied Microbiology · doi:10.1111/j.1365-2672.2004.02462.x · Cited by 51
Extraction, isolation and purification of exopolysaccharide from lactic acid bacteria using ethanol precipitation method
Bajpai, V. K., Majumder, R., Rather, I. A., & Kim, K. (2016) · Bangladesh Journal of Pharmacology · doi:10.3329/bjp.v11i3.27170 · Cited by 51
Influence of exopolysaccharide-producing lactic acid bacteria on the spreadability of fat-reduced raw fermented sausages (Teewurst)
Hilbig, J., Gisder, J., Prechtl, R. M., Herrmann, K., Weiß, J., & Loeffler, M. (2019) · Food Hydrocolloids · doi:10.1016/j.foodhyd.2019.01.056 · Cited by 51
Sulfonation of Lactobacillus plantarum WLPL04 exopolysaccharide amplifies its antioxidant activities in vitro and in a Caco-2 cell model
Liu, Z., Dong, L., Jia, K., Zhan, H., Zhang, Z., Shah, N. P., Tao, X., & Wei, H. (2019) · Journal of Dairy Science · doi:10.3168/jds.2018-15831 · Cited by 50
Cloning and sequencing of a gene coding for an extracellular dextransucrase (DSRB) fromLeuconostoc mesenteroidesNRRL B-1299 synthesizing only a α(1–6) glucan
Monchois, V., Remaud‐Siméon, M., MONSAN, P. F., & Willemot, R. (1998) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.1998.tb12876.x · Cited by 49
Preparation and biological activities of an exopolysaccharide produced by Enterobacter cloacae Z0206
Jin, M., Wang, Y., Xu, C., Lu, Z., Huang, M. H., & Wang, Y. (2010) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2010.03.020 · Cited by 49
Usage of in situ exopolysaccharide‐forming lactic acid bacteria in food production: Meat products—A new field of application?
Loeffler, M., Hilbig, J., Velasco, L., & Weiß, J. (2020) · Comprehensive Reviews in Food Science and Food Safety · doi:10.1111/1541-4337.12615 · Cited by 49
Exopolysaccharide from Bifidobacterium longum subsp. longum 35624™ modulates murine allergic airway responses
Schiavi, E., Plattner, S., Rodríguez‐Pérez, N., Barcik, W., Frei, R., Ferstl, R., Kurnik‐Łucka, M., Groeger, D., Grant, R. D., Roper, J., et al. (2018) · Beneficial Microbes · doi:10.3920/bm2017.0180 · Cited by 48
Conformational analysis of the exopolysaccharide from Burkholderia caribensis strain MWAP71: Impact on the interaction with soils
Vanhaverbeke, C., Heyraud, A., & Mazeau, K. (2003) · Biopolymers · doi:10.1002/bip.10432 · Cited by 46
Effect of Amaranth and Quinoa Flours on Exopolysaccharide Production and Protein Profile of Liquid Sourdough Fermented by Weissella cibaria and Lactobacillus plantarum
Valerio, F., Bavaro, A. R., Biase, M. D., Lonigro, S. L., Logrieco, A. F., & Lavermicocca, P. (2020) · Frontiers in Microbiology · doi:10.3389/fmicb.2020.00967 · Cited by 46
A potential role of Lactobacillus acidophilus LA1 and its exopolysaccharides on cancer cells in male albino mice
Ghany, K. A. E., Hamouda, R. A., Elhafez, E. A., Mahrous, H. A., Salem-Bekhit, M. M., & Hamza, H. A. (2015) · Biotechnology & Biotechnological Equipment · doi:10.1080/13102818.2015.1050455 · Cited by 43
Impact of starch and exopolysaccharide-producing lactic acid bacteria on the properties of set and stirred yoghurts
Gentès, M., Turgeon, S. L., & St‐Gelais, D. (2015) · International Dairy Journal · doi:10.1016/j.idairyj.2015.12.006 · Cited by 43
Food and Health Potentials of Exopolysaccharides Derived from Lactobacilli
Singh, P., & Saini, P. (2017) · Microbiology Research Journal International · doi:10.9734/mrji/2017/36935 · Cited by 43
Isolation of an Active Catalytic Core of Streptococcus downei MFe28 GTF-I Glucosyltransferase
Monchois, V., Arguello-Morales, M., & Russell, R. R. B. (1999) · Journal of Bacteriology · doi:10.1128/jb.181.7.2290-2292.1999 · Cited by 42
Production and properties of a dextransucrase from Leuconostoc mesenteroides IBT-PQ isolated from ' pulque ', a traditional Aztec alcoholic beverage
Chellapandian, M. N., Larios, C., Sánchez-González, M. N., & López-Munguı́a, A. (1998) · Journal of Industrial Microbiology & Biotechnology · doi:10.1038/sj.jim.2900560 · Cited by 38
Exopolysaccharides produced by lactic acid bacteria in food and probiotic applications
Ruas‐Madiedo, P., Salazar, N., & Reyes‐Gavilán, C. G. D. L. (2010) · Elsevier eBooks · doi:10.1016/b978-0-12-374546-0.00045-6 · Cited by 38
A New In Vitro Assay of Cholesterol Adsorption by Food and Microbial Polysaccharides
Soh, H.-S., Kim, C.-S., & Lee, S. (2003) · Journal of Medicinal Food · doi:10.1089/10966200360716643 · Cited by 37
Purification and characterization of basic glucosyltransferase from Streptococcus mutans serotype c
Mukasa, H., Shimamura, A., & Tsumori, H. (1982) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/0304-4165(82)90310-5 · Cited by 36
Enzymatic analysis of levan produced by lactic acid bacteria in fermented doughs
Shi, Q., Hou, Y., Xu, Y. B., Krogh, K. B. R. M., & Tenkanen, M. (2018) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2018.12.044 · Cited by 36

Research works printed but not linked: 2

Ullrich, M. (2009). Bacterial Polysaccharides: Current Innovations and Future Trends, Horizon Scientific Press.
Abedfar, 2016, Overview of the most important characterization of exopolysaccharides produced by probiotics bacteria and their biological function, J. Environ. Sci. Toxicol. Food Technol., 10, 47

Sorted by citations

Lactic Acid Bacteria in Raw-Milk Cheeses: From Starter Cultures to Probiotic Functions
Coelho, M. C., Malcata, F. X., & Silva, C. C. G. (2022) · Foods · doi:10.3390/foods11152276 · Cited by 276
“Some LAB species are able to synthesize and excrete extracellular polysaccharides [14,299].”
Self-citation
Exopolysaccharides Producing Bacteria: A Review
Netrusov, A. I., Liyaskina, E. V., Kurgaeva, I. V., Liyaskina, A. U., Yang, G., & Ревин, В. В. (2023) · Microorganisms · doi:10.3390/microorganisms11061541 · Cited by 197
Postbiotics: From emerging concept to application
Aggarwal, S., Sabharwal, V., Kaushik, P., Joshi, A., Aayushi, A., & Suri, M. (2022) · Frontiers in Sustainable Food Systems · doi:10.3389/fsufs.2022.887642 · Cited by 199
Postbiotics: Functional Food Materials and Therapeutic Agents for Cancer, Diabetes, and Inflammatory Diseases
Gurunathan, S., Pratheep, T., & Kim, J. (2023) · Foods · doi:10.3390/foods13010089 · Cited by 159
Biological Functions of Exopolysaccharides from Lactic Acid Bacteria and Their Potential Benefits for Humans and Farmed Animals
Werning, M. L., Hernández-Alcántara, A. M., Ruiz, M. J., Soto, L. P., Dueñas, M. T., López, P., & Frizzo, L. S. (2022) · Foods · doi:10.3390/foods11091284 · Cited by 132

See all 342

Authors: Jurášková, D., Ribeiro, S. C., & Silva, C. C. G.
Affiliations: Universidade dos Açores (PT)
Corresponding author: Silva, Celia C. G.
ORCID: Jurášková, Dominika
Ribeiro, Susana C.
Silva, Celia C. G.
Venue: Foods
Publisher: MDPI AG
Published: 2022-01-08
Volume: 11
Issue: 2
Pages: 156
ISSN: 2304-8158 (ISSN-L)
DOI: 10.3390/foods11020156
PMC: PMC8774684
OpenAlex: W4206529918
Cited by: 342
References: 235
Citations by year: 2026: 87 · 2025: 94 · 2024: 66 · 2023: 70 · 2022: 25
FWCI: 5.83
Type: journal article
Language: en
Open access: gold
doi.org
Licence: cc-by
creativecommons.org/licenses/by/4.0/ (vor)
Locations: Foods (publishedVersion, cc-by)
PubMed Central (publishedVersion, cc-by)
PubMed (publishedVersion)
DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders: Fundação para a Ciência e Tecnologia (UIDB/00153/2020, UI/BD/151108/2021)
Fundo regional para a Ciência e Tecnologia (M3.1.a/F/017/2018)
Topics: Life Sciences › Agricultural and Biological Sciences › Food Science › Polysaccharides Composition and Applications
Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
Health Sciences › Nursing › Nutrition and Dietetics › Microbial Metabolites in Food Biotechnology
Keywords: exopolysaccharides, lactic acid bacteria, exopolysaccharide biosynthesis, fermented foods, rheological properties, gut microbiota, prebiotics, immunomodulation, antioxidant activity, cholesterol lowering, anticarcinogenic activity, antibiofilm activity, antimicrobial activity, drug delivery, dairy products, gluten-free bakery products, low-fat meat products

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Exopolysaccharides Produced by Lactic Acid Bacteria: From Biosynthesis to Health-Promoting Properties

Abstract

Overview

Integrity signals

Figures

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks