Adaptations of Skeletal Muscle Mitochondria to Obesity, Exercise, and Polyunsaturated Fatty Acids
Abstract
Mitochondria intricately modulate their energy production through the control of mitochondrial adaptation (mitochondrial biogenesis, fusion, and/or fission) to meet energy demands. Nutrient overload may result in dysregulated mitochondrial biogenesis, morphology toward mitochondrial fragmentation, and oxidative stress in the skeletal muscle. In addition, physical activity and diet components influence mitochondrial function. Exercise may stimulate mitochondrial biogenesis and promote mitochondrial fusion/fission in the skeletal muscle. Moreover, some dietary fatty acids, such as n‐3 polyunsaturated fatty acids and conjugated linoleic acid, have been identified to positively regulate mitochondrial adaptation in the skeletal muscle. This review discusses the association of mitochondrial impairments and obesity, and presents an overview of various mechanisms of which exercise training and mitochondrial nutrients promote mitochondrial function in the skeletal muscle.
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A few weeks of HFD feeding can cause intramyocellular lipid accumulation and reduce mitochondrial function.
“Indeed, a few weeks of HFD feeding can cause intramyocellular lipid accumulation and reduce mitochondrial function [26].”
From A High-Fat Diet Induces Muscle Mitochondrial Dysfunction and Impairs Swimming Capacity in Zebrafish: A New Model of Sarcopenic Obesity (2022) · cites this paper as [26]
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1 retracted
Safdar, A., Little, J. P., Stokl, A., Hettinga, B. P., Akhtar, M., & Tarnopolsky, M. A. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.211466 · Cited by 309 · see citing works
RetractedIncreased oxidative stress in obesity and its impact on metabolic syndrome
Furukawa, S., Fujita, T., Shimabukuro, M., Iwaki, M., Yamada, Y., Nakajima, Y., Nakayama, O., Makishima, M., Matsuda, M., & Shimomura, I. (2004) · Journal of Clinical Investigation · doi:10.1172/jci21625 · Cited by 5,508 · see citing works
AMPK: a nutrient and energy sensor that maintains energy homeostasis
Hardie, D. G., Ross, F. A., & Hawley, S. A. (2012) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3311 · Cited by 4,602 · see citing works
Wu, Z., Puigserver, P., Andersson, U., Zhang, C., Adelmant, G., Mootha, V., Troy, A., Cinti, S., Lowell, B., Scarpulla, R. C., et al. (1999) · Cell · doi:10.1016/s0092-8674(00)80611-x · Cited by 4,139 · see citing works
Lagouge, M., Argmann, C., Gerhart-Hines, Z., Meziane, H., Lerin, C., Daussin, F., Messadeq, N., Milne, J., Lambert, P., Elliott, P., et al. (2006) · Cell · doi:10.1016/j.cell.2006.11.013 · Cited by 4,057 · see citing works
Mitochondrial Fission, Fusion, and Stress
Youle, R. J., & van der Bliek, A. M. (2012) · Science · doi:10.1126/science.1219855 · Cited by 3,674 · see citing works
Fission and selective fusion govern mitochondrial segregation and elimination by autophagy
Twig, G., Elorza, A., Molina, A. J. A., Mohamed, H., Wikstrom, J. D., Walzer, G., Stiles, L., Haigh, S. E., Katz, S., Las, G., et al. (2008) · The EMBO Journal · doi:10.1038/sj.emboj.7601963 · Cited by 3,082 · see citing works
Mitochondrial dysfunction and type 2 diabetes
Lowell, B. B., & Shulman, G. I. (2005) · Science · doi:10.1126/science.1104343 · Cited by 2,070 · see citing works
Koves, T. R., Ussher, J. R., Noland, R. C., Slentz, D., Mosedale, M., Ilkayeva, O., Bain, J., Stevens, R., Dyck, J. R. B., Newgard, C. B., et al. (2008) · Cell Metabolism · doi:10.1016/j.cmet.2007.10.013 · Cited by 1,990 · see citing works
Biochemical Adaptations in Muscle
Holloszy, J. O. (1967) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)96046-1 · Cited by 1,517 · see citing works
Estimation of skeletal muscle mass by bioelectrical impedance analysis
Janssen, I., Heymsfield, S. B., Baumgartner, R. N., & Ross, R. (2000) · Journal of Applied Physiology · doi:10.1152/jappl.2000.89.2.465 · Cited by 1,482 · see citing works
Mitochondrial Dynamics in the Regulation of Nutrient Utilization and Energy Expenditure
Liesa, M., & Shirihai, O. S. (2013) · Cell Metabolism · doi:10.1016/j.cmet.2013.03.002 · Cited by 1,341 · see citing works
Effect of conjugated linoleic acid on body composition in mice
Park, Y., Albright, K. J., Liu, W., Storkson, J. M., Cook, M. E., & Pariza, M. W. (1997) · Lipids · doi:10.1007/s11745-997-0109-x · Cited by 1,163 · see citing works
Self-citationRegulation of mitochondrial biogenesis
Jornayvaz, F. R., & Shulman, G. I. (2010) · Essays in Biochemistry · doi:10.1042/bse0470069 · Cited by 1,119 · see citing works
Mitofusin-2 Determines Mitochondrial Network Architecture and Mitochondrial Metabolism
Bach, D., Pich, S., Soriano, F. X., Vega, N., Baumgartner, B., Oriola, J., Daugaard, J. R., Lloberas, J., Camps, M., Zierath, J. R., et al. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m212754200 · Cited by 832 · see citing works
Bonnard, C., Durand, A., Peyrol, S., Chanseaume, E., Chauvin, M.-A., Morio, B., Vidal, H., & Rieusset, J. (2008) · Journal of Clinical Investigation · doi:10.1172/jci32601 · Cited by 819 · see citing works
Park, Y., Storkson, J. M., Albright, K. J., Liu, W., & Pariza, M. W. (1999) · Lipids · doi:10.1007/s11745-999-0358-8 · Cited by 815 · see citing works
Self-citationA Human Dynamin-related Protein Controls the Distribution of Mitochondria
Смирнова, Е. А., Shurland, D., Ryazantsev, S. N., & van der Bliek, A. M. (1998) · The Journal of Cell Biology · doi:10.1083/jcb.143.2.351 · Cited by 734 · see citing works
Mozdy, A. D., McCaffery, J. M., & Shaw, J. M. (2000) · The Journal of Cell Biology · doi:10.1083/jcb.151.2.367 · Cited by 725 · see citing works
Skeletal muscle enzymes and fiber composition in male and female track athletes
COSTILL, D. L., Daniels, J., Evans, W. J., Fink, W., Krahenbuhl, G. S., & Saltin, B. (1976) · Journal of Applied Physiology · doi:10.1152/jappl.1976.40.2.149 · Cited by 700 · see citing works
Jheng, H.-F., Tsai, P.-J., Guo, S.-M., Kuo, L.-H., Chang, C.-S., Su, I.-J., Chang, C.-R., & Tsai, Y.-S. (2012) · Molecular and Cellular Biology · doi:10.1128/mcb.05603-11 · Cited by 650 · see citing works
Sparks, L. M., Xie, H., Koza, R. A., Mynatt, R., Hulver, M. W., Bray, G. A., & Smith, S. R. (2005) · Diabetes · doi:10.2337/diabetes.54.7.1926 · Cited by 629 · see citing works
Wilkinson, S. B., Phillips, S. M., Atherton, P. J., Patel, R., Yarasheski, K. E., Tarnopolsky, M. A., & Rennie, M. J. (2008) · The Journal of Physiology · doi:10.1113/jphysiol.2008.153916 · Cited by 628 · see citing works
Conjugated Linoleic Acid Reduces Body Fat Mass in Overweight and Obese Humans
Gudmundsen, O., Blankson, H., Stakkestad, J. A., Fagertun, H., Thom, E., & Wadstein, J. (2000) · Journal of Nutrition · doi:10.1093/jn/130.12.2943 · Cited by 595 · see citing works
Mitochondrial filaments and clusters as intracellular power-transmitting cables
Skulachev, V. P. (2001) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(00)01735-7 · Cited by 477 · see citing works
Mitofusins 1/2 and ERRα expression are increased in human skeletal muscle after physical exercise
Cartoni, R., Léger, B., Hock, M. B., Praz, M., Crettenand, A., Pich, S., Ziltener, J., Luthi, F., Dériaz, O., Zorzano, A., et al. (2005) · The Journal of Physiology · doi:10.1113/jphysiol.2005.092031 · Cited by 406 · see citing works
Conjugated linoleic acid rapidly reduces body fat content in mice without affecting energy intake
DeLany, J. P., Blohm, F., Truett, A. A., Scimeca, J. A., & West, D. B. (1999) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1999.276.4.r1172 · Cited by 392 · see citing works
Mitochondrial Networking Protects β-Cells From Nutrient-Induced Apoptosis
Molina, A. J. A., Wikstrom, J. D., Stiles, L., Las, G., Mohamed, H., Elorza, A., Walzer, G., Twig, G., Katz, S., Corkey, B. E., et al. (2009) · Diabetes · doi:10.2337/db07-1781 · Cited by 381 · see citing works
Implication of Conjugated Linoleic Acid (CLA) in Human Health
Dilzer, A., & Park, Y. (2012) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2010.501409 · Cited by 377 · see citing works
Self-citationAMPK regulation of fatty acid metabolism and mitochondrial biogenesis: implications for obesity.
O’Neill, H. M., Holloway, G. P., & Steinberg, G. R. (2013) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2012.06.019 · Cited by 364 · see citing works
Changes in body composition in mice during feeding and withdrawal of conjugated linoleic acid
Park, Y., ALBRIGHT, K. J., STORKSON, J. M., Liu, W., Cook, M. E., & Pariza, M. W. (1999) · Lipids · doi:10.1007/s11745-999-0359-7 · Cited by 323 · see citing works
Self-citationApplied Physiology of Marathon Running
Sjödin, B., & Svedenhag, J. (1985) · Sports Medicine · doi:10.2165/00007256-198502020-00002 · Cited by 317 · see citing works
Resistance exercise training alters mitochondrial function in human skeletal muscle
PORTER, C., REIDY, P. T., BHATTARAI, N., SIDOSSIS, L. S., & RASMUSSEN, B. B. (2015) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000000605 · Cited by 288 · see citing works
Molecular mechanisms for mitochondrial adaptation to exercise training in skeletal muscle
Drake, J. C., Wilson, R. J., & Yan, Z. (2016) · The FASEB Journal · doi:10.1096/fj.15-276337 · Cited by 263 · see citing works
Conjugated Linoleic Acid: Potential Health Benefits as a Functional Food Ingredient
Kim, J. H., Kim, Y., Kim, Y. J., & Park, Y. (2016) · Annual Review of Food Science and Technology · doi:10.1146/annurev-food-041715-033028 · Cited by 244 · see citing works
Self-citationHirabara, S. M., Curi, R., & Maechler, P. (2010) · Journal of Cellular Physiology · doi:10.1002/jcp.21936 · Cited by 215 · see citing works
Suwa, M., Egashira, T., Nakano, H., Sasaki, H., & Kumagai, S. (2006) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00255.2006 · Cited by 210 · see citing works
(–)-Epicatechin enhances fatigue resistance and oxidative capacity in mouse muscle
Nogueira, L., Ramirez‐Sanchez, I., Perkins, G. A., Murphy, A., Taub, P. R., Ceballos, G., Villarreal, F. J., Hogan, M. C., & Malek, M. H. (2011) · The Journal of Physiology · doi:10.1113/jphysiol.2011.209924 · Cited by 205 · see citing works
Omega-3 Fatty Acids and Skeletal Muscle Health
Jeromson, S., Gallagher, I., Galloway, S., & Hamilton, D. (2015) · Marine Drugs · doi:10.3390/md13116977 · Cited by 203 · see citing works
Li, A., Zhang, S., Li, J., Liu, K., Huang, F., & Liu, B. (2016) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2016.06.008 · Cited by 197 · see citing works
Gaullier, J., Halse, J., Høivik, H. O., Høye, K., Syvertsen, C., Nurminiemi, M., Hassfeld, C., Einerhand, A. W. C., O’Shea, M., & Gudmundsen, O. (2007) · British Journal Of Nutrition · doi:10.1017/s0007114507381324 · Cited by 182 · see citing works
Drummond, M. J., Addison, O., Brunker, L., Hopkins, P. N., McClain, D. A., LaStayo, P. C., & Marcus, R. L. (2014) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/glu004 · Cited by 161 · see citing works
Koltai, E., Hart, N., Taylor, A. W., Goto, S., Ngo, J. K., Davies, K. J. A., & Radak, Z. (2012) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00337.2011 · Cited by 152 · see citing works
Ding, H., Jiang, N., Liu, H., Liu, X., Liu, D., Zhao, F., Wen, L., Liu, S., Ji, L. L., & Zhang, Y. (2009) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2009.08.007 · Cited by 149 · see citing works
Jamart, C., Naslain, D., Gilson, H., & Francaux, M. (2013) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00270.2013 · Cited by 148 · see citing works
Lionetti, L., Mollica, M. P., Donizzetti, I., Gifuni, G., Sica, R., Pignalosa, A., Cavaliere, G., Gaita, M., Filippo, C. D., Zorzano, A., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0092753 · Cited by 144 · see citing works
The molecular mechanism of mitochondrial fusion
Hoppins, S. C., & Nunnari, J. M. (2008) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2008.07.005 · Cited by 141 · see citing works
Fealy, C. E., Mulya, A., Lai, N., & Kirwan, J. P. (2014) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01064.2013 · Cited by 140 · see citing works
Holmström, M. H., Iglesias-Gutierrez, E., Zierath, J. R., & Garcia-Roves, P. M. (2012) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00159.2011 · Cited by 137 · see citing works
Kramer, J. K. G., Parodi, P. W., Jensen, R. G., Mossoba, M. M., Yurawecz, M. P., & Adlof, R. O. (1998) · Lipids · doi:10.1007/s11745-998-0279-6 · Cited by 133 · see citing works
Liu, J., Shen, W., Zhao, B., Wang, Y., Wertz, K., Weber, P., & Zhang, P. (2009) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2009.06.007 · Cited by 129 · see citing works
Ju, J.-S., Jeon, S.-I., Park, J.-Y., Lee, J.-Y., Lee, S.-C., Cho, K.-J., & Jeong, J.-M. (2016) · The Journal of Physiological Sciences · doi:10.1007/s12576-016-0440-9 · Cited by 125 · see citing works
Conjugated Linoleic Acid Supplementation for Twelve Weeks Increases Lean Body Mass in Obese Humans
Steck, S. E., Chalecki, A. M., Miller, P. C., Conway, J., Austin, G. L., Hardin, J. W., Albright, C. D., & Thuillier, P. (2007) · Journal of Nutrition · doi:10.1093/jn/137.5.1188 · Cited by 118 · see citing works
Vaughan, R. A., Garcia-Smith, R., Bisoffi, M., Conn, C. A., & Trujillo, K. A. (2012) · Lipids in Health and Disease · doi:10.1186/1476-511x-11-142 · Cited by 112 · see citing works
Human health effects of conjugated linoleic acid from milk and supplements
McCaffrey, T. A., Keaveney, E. M., Wallace, J. M. W., Binns, N. M., & Livingstone, M. B. E. (2011) · Nutrition Research Reviews · doi:10.1017/s0954422411000114 · Cited by 110 · see citing works
Bori, Z., Zhao, Z., Koltai, E., Fatouros, I. G., Jamurtas, A. Z., Douroudos, I. I., Terzis, G., Chatzinikolaou, A., Sovatzidis, A., Draganidis, D., et al. (2012) · Experimental Gerontology · doi:10.1016/j.exger.2012.03.004 · Cited by 108 · see citing works
Autophagy and Protein Turnover Signaling in Slow-Twitch Muscle during Exercise
PAGANO, A. F., PY, G., BERNARDI, H., CANDAU, R. B., & SANCHEZ, A. M. J. (2014) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000000237 · Cited by 96 · see citing works
Physical Exercise and Mitochondrial Function in Human Skeletal Muscle
Tonkonogi, M., & Sahlin, K. (2002) · Exercise and Sport Sciences Reviews · doi:10.1097/00003677-200207000-00007 · Cited by 91 · see citing works
Greene, N. P., Lee, D. E., Brown, J. L., Rosa, M. E., Brown, L. A., Perry, R. A., Henry, J. N., & Washington, T. A. (2015) · Physiological Reports · doi:10.14814/phy2.12470 · Cited by 89 · see citing works
Kamphuis, M. M. J. W., Lejeune, M. P. G. M., Saris, W. H. M., & Westerterp‐Plantenga, M. S. (2003) · European Journal of Clinical Nutrition · doi:10.1038/sj.ejcn.1601684 · Cited by 88 · see citing works
Bhattacharya, A., Rahman, M. M., Sun, D., Lawrence, R. A., Mejia, W., McCarter, R., O’Shea, M., & Fernandes, G. (2005) · Journal of Nutrition · doi:10.1093/jn/135.5.1124 · Cited by 85 · see citing works
Stangl, G. I. (2000) · Journal of Nutrition · doi:10.1093/jn/130.5.1140 · Cited by 83 · see citing works
The Effects of Conjugated Linoleic Acid Supplementation during Resistance Training
Pinkoski, C., Chilibeck, P. D., Candow, D. G., Esliger, D., Ewaschuk, J. B., Facci, M. R., Farthing, J. P., & Zello, G. A. (2006) · Medicine & Science in Sports & Exercise · doi:10.1249/01.mss.0000183860.42853.15 · Cited by 75 · see citing works
Johnson, M. L., Lalia, A. Z., Dasari, S., Pallauf, M., Fitch, M., Hellerstein, M. K., & Lanza, I. R. (2015) · Aging Cell · doi:10.1111/acel.12352 · Cited by 66 · see citing works
Colakoglu, S., Çolakoğlu, M., Taneli, F., Çetinöz, F., & Turkmen, M. (2006) · PubMed · Cited by 56 · see citing works
Kitaoka, Y., Ogasawara, R., Tamura, Y., Fujita, S., & Hatta, H. (2015) · Applied Physiology Nutrition and Metabolism · doi:10.1139/apnm-2015-0184 · Cited by 54 · see citing works
Exercise Pills: At the Starting Line
Li, S., & Laher, I. (2015) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2015.08.014 · Cited by 54 · see citing works
The effect of six different C18 fatty acids on body fat and energy metabolism in mice
Javadi, M., Everts, H., Hovenier, R., Kocsis, S., Lankhorst, A., Lemmens, A. G., Schonewille, J. T., Terpstra, A. H. M., & Beynen, A. C. (2004) · British Journal Of Nutrition · doi:10.1079/bjn20041217 · Cited by 51 · see citing works
Bissonauth, V., Chouinard, P. Y., Marin, J., Leblanc, N., Richard, D., & Jacques, H. (2005) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2005.10.010 · Cited by 48 · see citing works
Utilizing small nutrient compounds as enhancers of exercise-induced mitochondrial biogenesis
Craig, D. M., Ashcroft, S. P., Belew, M. Y., Stocks, B., Currell, K., Baar, K., & Philp, A. (2015) · Frontiers in Physiology · doi:10.3389/fphys.2015.00296 · Cited by 45 · see citing works
Exercise-induced oxidative stress and hypoxic exercise recovery
Ballmann, C. G., McGinnis, G. R., Peters, B. A., et al. (2014) · European Journal of Applied Physiology · doi:10.1007/s00421-013-2806-5 · Cited by 43 · see citing works
Conjugated linoleic acid (CLA) prevents age-associated skeletal muscle loss
Rahman, M. M., Halade, G. V., Jamali, A. E., & Fernandes, G. (2009) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2009.04.071 · Cited by 39 · see citing works
Exercise in a Pill: Feasibility of Energy Expenditure Targets
Himms-Hagen, J. (2004) · Current Drug Target -CNS & Neurological Disorders · doi:10.2174/1568007043337076 · Cited by 39 · see citing works
Genetic and metabolic effects on skeletal muscle AMPK in young and older twins
Mortensen, B., Poulsen, P., Wegner, L., Stender-Petersen, K. L., Ribel-Madsen, R., Friedrichsen, M., Birk, J. B., Vaag, A., & Wojtaszewski, J. F. P. (2009) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00058.2009 · Cited by 36 · see citing works
Zhu, T., Zhang, W., Luo, P., He, F., Ge, X.-Y., Zhang, Z., & Hu, C.-P. (2017) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2017.05.003 · Cited by 36 · see citing works
Kim, J. H., Kim, J., & Park, Y. (2012) · Lipids · doi:10.1007/s11745-012-3698-6 · Cited by 35 · see citing works
Self-citationStrenuous exercise induces mitochondrial damage in skeletal muscle of old mice
Lee, S., Kim, M., Lim, W., Kim, T., & Kang, C. (2015) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2015.04.038 · Cited by 35 · see citing works
Effect of CLA isomers and their mixture on aging C57Bl/6J mice
Halade, G. V., Rahman, M. M., & Fernandes, G. (2009) · European Journal of Nutrition · doi:10.1007/s00394-009-0029-7 · Cited by 33 · see citing works
Epigallocatechin gallate counteracts oxidative stress in docosahexaenoxic acid-treated myocytes
Casanova, E., Baselga‐Escudero, L., Ribas‐Latre, A., Arola‐Arnal, A., Bladé, C., Arola, L., & Salvadó, M. J. (2014) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2014.01.014 · Cited by 33 · see citing works
Kim, Y., & Park, Y. (2015) · Lipids · doi:10.1007/s11745-015-4000-5 · Cited by 32 · see citing works
Self-citationBhattacharya, A., Rahman, M. M., McCarter, R., O’Shea, M., & Fernandes, G. (2006) · Lipids · doi:10.1007/s11745-006-5117-3 · Cited by 29 · see citing works
Conjugated fatty acids increase energy expenditure in part by increasing voluntary movement in mice
Park, Y., & Park, Y. (2012) · Food Chemistry · doi:10.1016/j.foodchem.2012.01.051 · Cited by 26 · see citing works
Self-citationPileggi, C. A., Segovia, S. A., Markworth, J. F., Gray, C., Zhang, X. D., Milan, A. M., Mitchell, C. J., Barnett, M. P. G., Roy, N. C., Vickers, M. H., et al. (2015) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00351.2015 · Cited by 24 · see citing works
Kim, Y., Kim, D., & Park, Y. (2016) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2016.08.005 · Cited by 24 · see citing works
Self-citationHommelberg, P. P. H., Plat, J., Remels, A. H. V., van Essen, A. L. M., KELDERS, M. C. J. M., Mensink, R. P., Schols, A. M. W. J., & LANGEN, R. C. J. (2010) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201000103 · Cited by 23 · see citing works
EFFECTS OF CONJUGATED LINOLEIC ACID ISOMERS ON SERUM TUMOR NECROSIS FACTOR-A CONCENTRATION IN MICE
Park, Y., Yang, M., STORKSON, J. M., ALBRIGHT, K. J., Liu, W., Cook, M. E., & Pariza, M. W. (2007) · Journal of Food Biochemistry · doi:10.1111/j.1745-4514.2007.00110.x · Cited by 16 · see citing works
Self-citationMohankumar, S. K., Taylor, C. G., Siemens, L., & Zahradka, P. C. (2012) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2012.05.005 · Cited by 16 · see citing works
Oh, S.-L., Lee, S.-R., & Kim, J. (2017) · Physical Activity and Nutrition · doi:10.20463/jenb.2017.0028 · Cited by 10 · see citing works
Kim, Y., Kim, D., Good, D. J., & Park, Y. (2015) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.5b00840 · Cited by 8 · see citing works
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- Authors
- Chen, P. B., Yang, J. S., & Park, Y.
- Affiliations
- University of Massachusetts Amherst (US)
- Venue
- Lipids
- Publisher
- Wiley
- Published
- 2018-03
- Volume
- 53
- Issue
- 3
- Pages
- 271-278
- ISSN
- 0024-4201 (ISSN-L)
- 1558-9307
- OpenAlex
- W2801779130
- Cited by
- 37
- References
- 89
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 13 · 2023: 3 · 2022: 4 · 2021: 3 · 2020: 3 · 2019: 3 · 2018: 4
- FWCI
- 0.32
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Lipids (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Food and Agriculture
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Mitochondrial Function and Pathology
- Health Sciences › Medicine › Physiology › Adipose Tissue and Metabolism
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Muscle Physiology and Disorders
- Keywords
- skeletal muscle mitochondria, mitochondrial biogenesis, mitochondrial fusion, mitochondrial fission, mitochondrial fragmentation, obesity, exercise training, polyunsaturated fatty acids, omega-3 fatty acids, conjugated linoleic acid, oxidative stress, mitochondrial function
- MeSH terms
- Adaptation, Physiological, Animals, Organelle Biogenesis, Dietary Fats, Energy Metabolism, Gene Expression Regulation, Humans, Mitochondria, Muscle, Obesity, Exercise, Fatty Acids, Omega-3, Oxidative Stress, Muscle, Skeletal, Mitochondrial Proteins, Linoleic Acids, Conjugated
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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