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Cited by 283

The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.

Satellite cells and myonuclei in young and elderly women and men

Kadi, Fawzi, Charifi, Nadia, Denis, Christian, Lexell, Jan·2004·Muscle & Nerve
DOI 10.1002/mus.10510
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Abstract

The overall aim of this study was to assess the effects of aging on the satellite cell population. Muscle biopsies were taken from the tibialis anterior muscle of healthy, moderately active young (age range, 20–32 years;n= 31) and elderly (age range, 70–83 years;n= 27) women and men with comparable physical activity pattern. Satellite cells and myonuclei were visualized using a monoclonal antibody against neural cell adhesion molecule and counterstained with Mayer's hematoxylin. An average of 211 (range, 192–241) muscle fibers were examined for each individual. Compared with the young women and men, the elderly subjects had a significantly lower (P< 0.011) number of satellite cells per muscle fiber but a significantly higher (P< 0.004) number of myonuclei per muscle fiber. The number of satellite cells relative to the total number of nuclei [satellite cells/(myonuclei + satellite cells)] was significantly lower in the elderly than in the young women and men. These results imply that a reduction in the satellite cell population occurs as a result of increasing age in healthy men and women. Muscle Nerve 29: 120–127, 2004

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Metadata

Authors
Kadi, F., Charifi, N., Denis, C., & Lexell, J.
Venue
Muscle & Nerve
Publisher
Wiley
Published
2003-11-04
Volume
29
Issue
1
Pages
120-127
ISSN
  • 0148-639X (ISSN-L)
  • 1097-4598
DOI
10.1002/mus.10510
OpenAlex
W2124496828
Cited by
283
References
4
FWCI
2.14
Type
journal article
Language
en
Open access
closed

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