Perfluorinated compounds in aquatic organisms at various trophic levels in a Great Lakes food chain
Open accessAbstract
Trophic transfer of perfluorooctanesulfonate (PFOS) and other related perfluorinated compounds was examined in a Great Lakes benthic foodweb including water-algae-zebra mussel-round goby-smallmouth bass. In addition, perfluorinated compounds were measured in livers and eggs of Chinook salmon and lake whitefish, in muscle tissue of carp, and in eggs of brown trout collected from Michigan. Similarly, green frog livers, snapping turtle plasma, mink livers, and bald eagle tissues were analyzed to determine concentrations in higher trophic-level organisms in the food chain. PFOS was the most widely detected compound in benthic organisms at various trophic levels. Concentrations of PFOS in benthic invertebrates such as amphipods and zebra mussels were approximately 1000-fold greater than those in surrounding water, which suggested a bioconcentration factor (BCF; concentration in biota/concentration in water) of 1000 in benthic invertebrates. Concentrations of PFOS in round gobies were two- to fourfold greater than those in their prey organisms such as zebra mussels and amphipods. Concentrations of PFOS in predatory fishes (Chinook salmon and lake whitefish) were 10 to 20-fold greater than those in their prey species. Concentrations of PFOS in mink and bald eagles were, on average, 5- to 10-fold greater than those in Chinook salmon, carp, or snapping turtles. Because of the accumulation of PFOS in liver and blood, the biomagnification factor (BMF) of perfluorinated compounds in higher trophic-level organisms such as salmonid fishes, mink, and eagles were based on the concentrations in livers or plasma. Overall, these results suggest a BCF of PFOS of approximately 1000 (whole-body based) in benthic invertebrates, and a BMF of 10 to 20 in mink or bald eagles, relative to their prey items. Eggs of fish contained notable concentrations of PFOS, suggesting oviparous transfer of this compound. PFOA was found in water, but its biomagnification potential was lower than that of PFOS.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
PFASs may have adverse effects on wildlife and humans through the food web.
“Thus PFASs may have adverse effects on wild life and even human beings through the food web”
From Short- and long-chain perfluoroalkyl substances in the water, suspended particulate matter, and surface sediment of a turbid river (2016) · cites this paper as Kannan et al., 2005
The Results and Discussion (page unavailable) report that PFOS biomagnifies through a Great Lakes food chain, with the highest concentrations in mink and bald eagles. This supports food-web exposure in wildlife, but the paper does not establish adverse effects or address effects in humans. (LLM, conf=0.85)
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Global Distribution of Perfluorooctane Sulfonate in Wildlife
Giesy, J. P., & Kannan, K. (2001) · Environmental Science & Technology · doi:10.1021/es001834k · Cited by 2,750 · see citing works
Self-citation(1995) · Environmental Science and Pollution Research · doi:10.1007/bf02986737 · Cited by 1,126 · see citing works
Peer Reviewed: Perfluorochemical Surfactants in the Environment
Giesy, J. P., & Kannan, K. (2002) · Environmental Science & Technology · doi:10.1021/es022253t · Cited by 1,103 · see citing works
Self-citationMartin, J. W., Mabury, S. A., Solomon, K. R., & Muir, D. C. G. (2003) · Environmental Toxicology and Chemistry · doi:10.1002/etc.5620220126 · Cited by 960 · see citing works
Compound-specific, quantitative characterization of organic fluorochemicals in biological matrices
Hansen, K. J., Clemen, L. A., Ellefson, M. E., & Johnson, H. O. (2001) · Environmental Science & Technology · doi:10.1021/es001489z · Cited by 923 · see citing works
Identification of Long-Chain Perfluorinated Acids in Biota from the Canadian Arctic
Martin, J. W., Smithwick, M., Braune, B. M., Hoekstra, P. F., Muir, D. C. G., & Mabury, S. A. (2003) · Environmental Science & Technology · doi:10.1021/es034727+ · Cited by 667 · see citing works
Moody, C. A., Martin, J. W., Kwan, W. C., Muir, D. C. G., & Mabury, S. A. (2001) · Environmental Science & Technology · doi:10.1021/es011001+ · Cited by 554 · see citing works
Quantitative Characterization of Trace Levels of PFOS and PFOA in the Tennessee River
Hansen, K. J., Johnson, H. O., Eldridge, J. S., Butenhoff, J. L., & Dick, L. A. (2002) · Environmental Science & Technology · doi:10.1021/es010780r · Cited by 539 · see citing works
Taniyasu, S., Kannan, K., Horii, Y., Hanari, N., & Yamashita, N. (2003) · Environmental Science & Technology · doi:10.1021/es0303440 · Cited by 509 · see citing works
Self-citationAccumulation of Perfluorooctane Sulfonate in Marine Mammals
Kannan, K., Koistinen, J., Beckmen, K. B., Evans, T. J., Gorzelany, J. F., Hansen, K. J., Jones, P. D., Helle, E., Nyman, M., & Giesy, J. P. (2001) · Environmental Science & Technology · doi:10.1021/es001873w · Cited by 489 · see citing works
Self-citationKannan, K., Corsolini, S., Falandysz, J., Oehme, G., Focardi, S. E., & Giesy, J. P. (2002) · Environmental Science & Technology · doi:10.1021/es020519q · Cited by 434 · see citing works
Self-citationQuantitative determination of fluorotelomer sulfonates in groundwater by LC MS/MS
Schultz, M. M., Barofsky, D. F., & Field, J. A. (2004) · Environmental Science & Technology · doi:10.1021/es035031j · Cited by 373 · cited 2× · see citing works
“2003), but severalfold lower than those reported for areas impacted by local sources of contamination (Schultz et al. 2004; Hansen et al. 2002; Moody et al. 2002).”
BackgroundResultYamashita, N., Kannan, K., Taniyasu, S., Horii, Y., Okazawa, T., Petrick, G., & Gamo, T. (2004) · Environmental Science & Technology · doi:10.1021/es0492541 · Cited by 367 · see citing works
Self-citationNeuroendocrine Effects of Perfluorooctane Sulfonate in Rats
Austin, M. E., Kasturi, B. S., Barber, M., Kannan, K., MohanKumar, P. S., & MohanKumar, S. M. J. (2003) · Environmental Health Perspectives · doi:10.1289/ehp.6128 · Cited by 347 · see citing works
Self-citationPerfluorooctane Sulfonate in Fish-Eating Water Birds Including Bald Eagles and Albatrosses
Kannan, K., Franson, J. C., Bowerman, W. W., Hansen, K. J., Jones, P. D., & Giesy, J. P. (2001) · Environmental Science & Technology · doi:10.1021/es001935i · Cited by 304 · see citing works
Self-citationPolyfluorinated Telomer Alcohols and Sulfonamides in the North American Troposphere
Stock, N. L., Lau, F. K., Ellis, D. A., Martin, J. W., Muir, D. C. G., & Mabury, S. A. (2004) · Environmental Science & Technology · doi:10.1021/es034644t · Cited by 247 · see citing works
Tomy, G. T., Tittlemier, S. A., Palace, V. P., Budakowski, W. R., Braekevelt, E., Brinkworth, L., & Friesen, K. J. (2003) · Environmental Science & Technology · doi:10.1021/es034550j · Cited by 231 · see citing works
Concentrations of perfluorinated acids in livers of birds from Japan and Korea
Kannan, K., Choi, J., Iseki, N., Senthilkumar, K., Kim, D. H., Masunaga, S., & Giesy, J. P. (2002) · Chemosphere · doi:10.1016/s0045-6535(02)00304-1 · Cited by 220 · see citing works
Self-citationKannan, K., Newsted, J. L., Halbrook, R. S., & Giesy, J. P. (2002) · Environmental Science & Technology · doi:10.1021/es0205028 · Cited by 195 · see citing works
Self-citationJude, D. J., Janssen, J., & Crawford, G. (1995) · Michigan State University Press eBooks · doi:10.14321/j.ctt1pwtcm0.25 · Cited by 175 · see citing works
Self-citationJOHNSON, J. (1984) · Fundamental and Applied Toxicology · doi:10.1016/0272-0590(84)90235-5 · Cited by 161 · see citing works
Perfluorooctane Sulfonate Concentrations in Surface Water in Japan
Saito, N., Sasaki, K., Nakatome, K., Harada, K. H., Yoshinaga, T., & Koizumi, A. (2003) · Archives of Environmental Contamination and Toxicology · doi:10.1007/s00244-003-0163-9 · Cited by 152 · see citing works
de Vijver, K. I. V., Hoff, P. T., Das, K., Dongen, W. V., Esmans, E. L., Jauniaux, T. P., Bouquegneau, J.-M., Blust, R., & Coen, W. D. (2003) · Environmental Science & Technology · doi:10.1021/es0345975 · Cited by 133 · see citing works
Bruner, K. A., Fisher, S. W., & Landrum, P. F. (1994) · Journal of Great Lakes Research · doi:10.1016/s0380-1330(94)71190-4 · Cited by 133 · see citing works
The Lake Huron Ecosystem: Ecology, Fisheries and Management
Munawar, M., Edsall, T. A., & Leach, J. H. (1995) · Cited by 126 · see citing works
Kannan, K., Hansen, K. J., Wade, T. L., & Giesy, J. P. (2002) · Archives of Environmental Contamination and Toxicology · doi:10.1007/s00244-001-0003-8 · Cited by 115 · see citing works
Self-citationRattner, B. A., McGowan, P. C., Golden, N. H., et al. (2004) · Archives of Environmental Contamination and Toxicology · doi:10.1007/s00244-003-3160-0 · Cited by 70 · see citing works
Hanari, N., Kannan, K., Horii, Y., et al. (2004) · Archives of Environmental Contamination and Toxicology · doi:10.1007/s00244-003-3106-6 · Cited by 68 · see citing works
Self-citationVapor Pressures of the Fluorinated Telomer AlcoholsLimitations of Estimation Methods
Stock, N. L., Ellis, D. A., Deleebeeck, L., Muir, D. C. G., & Mabury, S. A. (2004) · Environmental Science & Technology · doi:10.1021/es034773+ · Cited by 66 · see citing works
Predation of zebra mussels by crayfish
Martin, G. W., & Corkum, L. D. (1994) · Canadian Journal of Zoology · doi:10.1139/z94-254 · Cited by 66 · see citing works
Kumar, S., Kannan, K., Giesy, J. P., et al. (2002) · Environmental Science & Technology · doi:10.1021/es0114660 · Cited by 45 · see citing works
Self-citationCommon Carp Diet Includes Zebra Mussels and Lake Trout Eggs
Marsden, J. E. (1997) · Journal of Freshwater Ecology · doi:10.1080/02705060.1997.9663559 · Cited by 23 · see citing works
Savitz, J., Bardygula, L. G., & Scoma, L. (1996) · Journal of Freshwater Ecology · doi:10.1080/02705060.1996.9664475 · Cited by 8 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Conder, J. M., Hoke, R. A., Wolf, W. D., Russell, M. H., & Buck, R. C. (2008) · Environmental Science & Technology · doi:10.1021/es070895g · Cited by 1,206 · see citing works
Fate and Effects of Poly- and Perfluoroalkyl Substances in the Aquatic Environment: A Review
Ahrens, L., & Bundschuh, M. (2014) · Environmental Toxicology and Chemistry · doi:10.1002/etc.2663 · Cited by 817 · see citing works
Accumulation of perfluorinated alkyl substances (PFAS) in agricultural plants: A review
Ghisi, R., Vamerali, T., & Manzetti, S. (2019) · Environmental Research · doi:10.1016/j.envres.2018.10.023 · Cited by 705 · see citing works
Mass Loading and Fate of Perfluoroalkyl Surfactants in Wastewater Treatment Plants
Sinclair, E., & Kannan, K. (2006) · Environmental Science & Technology · doi:10.1021/es051798v · Cited by 547 · see citing works
Self-citationEstimating Consumer Exposure to PFOS and PFOA
Trudel, D., Horowitz, L., Wormuth, M., Scheringer, M., Cousins, I. T., & Hungerbühler, K. (2008) · Risk Analysis · doi:10.1111/j.1539-6924.2008.01017.x · Cited by 514 · see citing works
Rayne, S., & Forest, K. (2009) · Journal of Environmental Science and Health, Part A · doi:10.1080/10934520903139811 · Cited by 475 · see citing works
Ankley, G. T., Cureton, P., Hoke, R. A., Houde, M., Kumar, A., Kurias, J., Lanno, R., McCarthy, C., Newsted, J., Salice, C. J., et al. (2020) · Environmental Toxicology and Chemistry · doi:10.1002/etc.4869 · Cited by 454 · see citing works
Immunotoxicity of Perfluorinated Compounds: Recent Developments
DeWitt, J. C., Peden-Adams, M. M., Keller, J. M., & Germolec, D. R. (2012) · Toxicologic Pathology · doi:10.1177/0192623311428473 · Cited by 457 · see citing works
Crone, B. C., Speth, T. F., Wahman, D. G., Smith, S. J., Abulikemu, G., Kleiner, E. J., & Pressman, J. G. (2019) · Critical Reviews in Environmental Science and Technology · doi:10.1080/10643389.2019.1614848 · Cited by 408 · see citing works
Brase, R. A., Mullin, E. J., & Spink, D. C. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22030995 · Cited by 374 · see citing works
Trophic Magnification of Poly- and Perfluorinated Compounds in a Subtropical Food Web
Loi, E. I. H., Yeung, L. W. Y., Taniyasu, S., Lam, P. K. S., Kannan, K., & Yamashita, N. (2011) · Environmental Science & Technology · doi:10.1021/es200432n · Cited by 335 · see citing works
Self-citationZhao, P., Xia, X., Dong, J., Xia, N., Jiang, X., Li, Y., & Zhu, Y. (2016) · Science of The Total Environment · doi:10.1016/j.scitotenv.2016.05.221 · Cited by 322 · see citing works
Martin, J. W., Asher, B. J., Beesoon, S., Benskin, J. P., & Ross, M. S. (2010) · Journal of Environmental Monitoring · doi:10.1039/c0em00295j · Cited by 311 · see citing works
Filipovic, M., Woldegiorgis, A., Norström, K., Bibi, M., Lindberg, M., & Österås, A.-H. (2015) · Chemosphere · doi:10.1016/j.chemosphere.2014.09.005 · Cited by 284 · see citing works
PFAS Environmental Pollution and Antioxidant Responses: An Overview of the Impact on Human Field
Bonato, M., Corrà, F., Bellio, M., Guidolin, L., Tallandini, L., Irato, P., & Santovito, G. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17218020 · Cited by 243 · see citing works
Nontargeted mass-spectral detection of chloroperfluoropolyether carboxylates in New Jersey soils
Washington, J. W., Rosal, C. G., McCord, J. P., Strynar, M. J., Lindstrom, A. B., Bergman, E. L., Goodrow, S. M., Tadesse, H. K., Pilant, A. N., Washington, B. J., et al. (2020) · Science · doi:10.1126/science.aba7127 · Cited by 225 · see citing works
Australia-wide assessment of perfluoroalkyl substances (PFASs) in landfill leachates
Gallen, C., Drage, D., Eaglesham, G., Grant, S., Bowman, M., & Mueller, J. F. (2017) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2017.02.006 · Cited by 224 · see citing works
Land, M., de Wit, C. A., Bignert, A., Cousins, I. T., Herzke, D., Johansson, J. H., & Martin, J. W. (2018) · Environmental Evidence · doi:10.1186/s13750-017-0114-y · Cited by 219 · see citing works
“PFSAs are fully dissociated anions in environmental media [53] and tend to accumulate in surface waters [31], they are persistent, bind weakly to organic phases [54] compared to other persistent organic substances, bioaccumulate in laboratory studies [55, 56] and biomagnify in food webs [57, 58].”
de Solla, S. R., De Silva, A. O., & Letcher, R. J. (2012) · Environment International · doi:10.1016/j.envint.2011.09.011 · Cited by 198 · see citing works
Perfluorinated and Polyfluorinated Compounds in Lake Food Webs from the Canadian High Arctic
Lescord, G. L., Kidd, K. A., De Silva, A. O., Williamson, M., Spencer, C., Wang, X., & Muir, D. C. G. (2015) · Environmental Science & Technology · doi:10.1021/es5048649 · Cited by 192 · see citing works
Lam, N. H., Cho, C.-R., Kannan, K., & Cho, H.-S. (2017) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2016.04.010 · Cited by 188 · see citing works
Self-citationPerfluorochemicals in water reuse
Plumlee, M. H., Larabee, J., & Reinhard, M. (2008) · Chemosphere · doi:10.1016/j.chemosphere.2008.04.057 · Cited by 138 · see citing works
Uptake, accumulation and metabolism of PFASs in plants and health perspectives: A critical review
Jiao, X., Shi, Q., & Gan, J. (2021) · Critical Reviews in Environmental Science and Technology · doi:10.1080/10643389.2020.1809219 · Cited by 121 · see citing works
Jantzen, C. E., Annunziato, K. M., & Cooper, K. R. (2016) · Aquatic Toxicology · doi:10.1016/j.aquatox.2016.09.011 · Cited by 113 · see citing works
Jarvis, A. L., Justice, J. R., Elias, M. C., Schnitker, B., & Gallagher, K. (2021) · Environmental Toxicology and Chemistry · doi:10.1002/etc.5147 · Cited by 105 · see citing works
Lee, H.-G., Lee, Y. J., & Yang, J.-H. (2012) · NeuroToxicology · doi:10.1016/j.neuro.2012.01.017 · Cited by 97 · see citing works
Peden-Adams, M. M., Stuckey, J. E., Gaworecki, K. M., Berger-Ritchie, J., Bryant, K., Jodice, P. G., Scott, T. R., Ferrario, J. B., Guan, B., Vigo, C., et al. (2009) · Reproductive Toxicology · doi:10.1016/j.reprotox.2008.10.009 · Cited by 84 · see citing works
Lee, H., De Silva, A. O., & Mabury, S. A. (2012) · Environmental Science & Technology · doi:10.1021/es204533m · Cited by 78 · see citing works
Chen, Y., Fu, J., Ye, T., Li, X., Gao, K., Xue, Q., Lv, J., Zhang, A., & Fu, J. (2021) · Journal of Environmental Sciences · doi:10.1016/j.jes.2021.03.036 · Cited by 69 · see citing works
Liu, J., Zhao, X., Liu, Y., Qiao, X., Wang, X., Ma, M., Jin, X., Liu, C., Zheng, B., Shen, J., et al. (2019) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2019.109454 · Cited by 64 · see citing works
Harada, K. H., Ishii, T. M., Takatsuka, K., Koizumi, A., & Ohmori, H. (2006) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2006.10.038 · Cited by 58 · see citing works
Sebastiano, M., Jouanneau, W., Blévin, P., Angelier, F., Parenteau, C., Gernigon, J., Lemesle, J. C., Robin, F., Pardon, P., Budzinski, H., et al. (2021) · Science of The Total Environment · doi:10.1016/j.scitotenv.2020.144611 · Cited by 51 · see citing works
Larson, E. S., Conder, J. M., & Arblaster, J. A. (2018) · Chemosphere · doi:10.1016/j.chemosphere.2018.03.004 · Cited by 38 · see citing works
Zhang, Z., Peng, H., Wan, Y., & Hu, J. (2015) · Environmental Science & Technology · doi:10.1021/es504445x · Cited by 35 · see citing works
Becker, A. M., Suchan, M., Gerstmann, S., & Frank, H. (2010) · Environmental Science and Pollution Research · doi:10.1007/s11356-010-0335-x · Cited by 34 · see citing works
- Authors
- Kannan, K., Tao, L., Sinclair, E., Pastva, S. D., Jude, D. J., & Giesy, J. P.
- Affiliations
- New York State Department of Health (US)
- Michigan State University (US)
- University of Michigan (US)
- City University of Hong Kong (HK)
- Corresponding author
- Kannan, Kurunthachalam
- Venue
- Archives of Environmental Contamination and Toxicology
- Published
- 2005-03-26
- Volume
- 48
- Issue
- 4
- Pages
- 559-566
- ISSN
- 0090-4341 (ISSN-L)
- 1432-0703
- OpenAlex
- W2142983024
- Cited by
- 530
- References
- 33
- Citations by year
- 2026: 12 · 2025: 23 · 2024: 20 · 2023: 20 · 2022: 14 · 2021: 26 · 2020: 31 · 2019: 26 · 2018: 27 · 2017: 26 · 2016: 26 · 2015: 21 · 2014: 22 · 2013: 28 · 2012: 36
- FWCI
- 17.56
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Archives of Environmental Contamination and Toxicology (publishedVersion)
- PubMed (publishedVersion)
- Deep Blue (University of Michigan) (submittedVersion)
- Topics
- Physical Sciences › Environmental Science › Environmental Chemistry › Per- and polyfluoroalkyl substances research
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Toxic Organic Pollutants Impact
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Environmental Toxicology and Ecotoxicology
- Keywords
- PFOS, perfluorinated compounds, perfluorooctanoic acid, trophic transfer, biomagnification, bioconcentration factor, food chain, Great Lakes, benthic invertebrates, Dreissena polymorpha, Neogobius melanostomus, Oncorhynchus tshawytscha, lake whitefish, mink, bald eagle, snapping turtle, carp, green frog
- MeSH terms
- Animals, Environmental Monitoring, Fishes, Fluorocarbons, Great Lakes Region, Invertebrates, Liver, Michigan, Mink, Muscles, Ovum, Ranidae, Turtles, Water Pollutants, Chemical, Eagles, Food Chain, Rivers, Eukaryota
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
