Oxytocin and rodent sociosexual responses: from behavior to gene expression

Handbook of Physiology.

Plum, F. (1960) · Archives of Neurology · doi:10.1001/archneur.1960.03840090124020 · Cited by 10,388 · see citing works

The Physiology of Reproduction

Blandau, R. J. (1988) · JAMA · doi:10.1001/jama.1988.03410200127050 · Cited by 3,000 · see citing works

The regulation and function of c-fos and other immediate early genes in the nervous system

Sheng, M., & Greenberg, M. E. (1990) · Neuron · doi:10.1016/0896-6273(90)90106-p · Cited by 2,432 · see citing works

Expression of c- <i>fos</i> Protein in Brain: Metabolic Mapping at the Cellular Level

Sagar, S. M., Sharp, F. R., & Curran, T. (1988) · Science · doi:10.1126/science.3131879 · Cited by 1,925 · see citing works

Intra- and extrahypothalamic vasopressin and oxytocin pathways in the rat

Buijs, R. M. (1978) · Cell and Tissue Research · doi:10.1007/bf00212323 · Cited by 830 · see citing works

Plasma oxytocin increases in the human sexual response

CARMICHAEL, M. S., HUMBERT, R., DIXEN, J., PALMISANO, G., GREENLEAF, W., & DAVIDSON, J. M. (1987) · The Journal of Clinical Endocrinology &amp; Metabolism · doi:10.1210/jcem-64-1-27 · Cited by 554 · see citing works

Localization and pharmacological characterization of high affinity binding sites for vasopressin and oxytocin in the rat brain by light microscopic autoradiography

Tribollet, E., Barberis, C., Jard, S., Dubois-Dauphin, M., & Dreifuss, J. J. (1988) · Brain Research · doi:10.1016/0006-8993(88)91437-0 · Cited by 442 · see citing works

Morphology of vasopressin and oxytocin neurones and their central and vascular projections

Sofroniew, M. V. (1983) · Progress in Brain Research · doi:10.1016/s0079-6123(08)64378-2 · Cited by 370 · see citing works

Neurophysiology and neuropharmacology of hypothalamic magnocellular neurons secreting vasopressin and oxytocin

Renaud, L. P., & Bourquet, C. W. (1991) · Progress in Neurobiology · doi:10.1016/0301-0082(91)90020-2 · Cited by 346 · see citing works

Increased expression of c-fos in the medial preoptic area after mating in male rats: Role of afferent inputs from the medial amygdala and midbrain central tegmental field

Baum, M. J., & Everitt, B. J. (1992) · Neuroscience · doi:10.1016/0306-4522(92)90452-8 · Cited by 342 · see citing works

Changes in oxytocin and vasopressin secretion during sexual activity in men

MURPHY, M. R., SECKL, J. R., BURTON, S., CHECKLEY, S. A., & LIGHTMAN, S. L. (1987) · The Journal of Clinical Endocrinology &amp; Metabolism · doi:10.1210/jcem-65-4-738 · Cited by 318 · see citing works

Corticotropin-releasing factor: co-expression within distinct subsets of oxytocin-, vasopressin-, and neurotensin-immunoreactive neurons in the hypothalamus of the male rat

Sawchenko, P. E., Swanson, L. W., & Vale, W. (1984) · Journal of Neuroscience · doi:10.1523/jneurosci.04-04-01118.1984 · Cited by 305 · see citing works

Relationships among cardiovascular, muscular, and oxytocin responses during human sexual activity

Carmichael, M. S., Warburton, V. L., Dixen, J., & Davidson, J. M. (1994) · Archives of Sexual Behavior · doi:10.1007/bf01541618 · Cited by 276 · see citing works

Reflex control of magnocellular vasopressin and oxytocin secretion

Cunningham, E. T., & Sawchenko, P. E. (1991) · Trends in Neurosciences · doi:10.1016/0166-2236(91)90032-p · Cited by 266 · see citing works

Neural Mechanisms of Female Reproductive Behavior

Pfaff, D. W., & Modianos, D. T. (1985) · Springer eBooks · doi:10.1007/978-1-4684-4832-0_10 · Cited by 255 · see citing works

125I-labelled d(CH2)5[Tyr(Me)2,Thr4,Tyr-NH29]OVT: a selective oxytocin receptor ligand

Elands, J., Barberis, C., Jard, S., Tribollet, E., Dreifuss, J.-J., Bankowski, K., Manning, M., & Sawyer, W. H. (1988) · European Journal of Pharmacology · doi:10.1016/0014-2999(88)90778-9 · Cited by 245 · see citing works

Enhanced social interactions in rats following chronic, centrally infused oxytocin

Witt, D. M., Winslow, J. T., & Insel, T. R. (1992) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(92)90418-f · Cited by 244 · see citing works

Oxytocin and Social Bondinga

CARTER, C. S., WILLIAMS, J. R., WITT, D. M., & INSEL, T. R. (1992) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1992.tb34356.x · Cited by 237 · see citing works

Oxytocin facilitates the sexual receptivity of estrogen-treated female rats

Caldwell, J. D., Prange, A. J., & Pedersen, C. A. (1986) · Neuropeptides · doi:10.1016/0143-4179(86)90093-4 · Cited by 229 · see citing works

Behavioral Effects of Progesterone Associated with Rapid Modulation of Oxytocin Receptors

Schumacher, M., Coirini, H., Pfaff, D. W., & McEwen, B. S. (1990) · Science · doi:10.1126/science.2173139 · Cited by 221 · see citing works

Gonadal steroids regulate oxytocin receptors but not vasopressin receptors in the brain of male and female rats. An autoradiographical study

Tribollet, E., Audigier, S., Dubois-Dauphin, M., & Dreifuss, J. J. (1990) · Brain Research · doi:10.1016/0006-8993(90)90232-z · Cited by 203 · see citing works

Estradiol Modulates Density of Putative Oxytocin Receptors’ in Discrete Rat Brain Regions

de Kloet, R., Voorhuis, D. A. M., Boschma, Y., & Elands, J. (2008) · Neuroendocrinology · doi:10.1159/000124680 · Cited by 198 · see citing works

Pharmacological characteristics and anatomical distribution of [3H]oxytocin-binding sites in the wistar rat brain studied by autoradiography

Freund-Mercier, M. J., Stoeckel, M. E., Palacios, J. M., Pazos, A., Reichhart, J. M., Porte, A., & Richard, P. (1987) · Neuroscience · doi:10.1016/0306-4522(87)90113-8 · Cited by 192 · see citing works

Oxytocin-induced penile erection and yawning: site of action in the brain

Melis, M. R., Argiolas, A., & Gessa, G. L. (1986) · Brain Research · doi:10.1016/0006-8993(86)91485-x · Cited by 190 · see citing works

Neurochemical Regulation of Oxytocin Secretion in Lactation*

Crowley, W. R., & Armstrong, W. E. (1992) · Endocrine Reviews · doi:10.1210/edrv-13-1-33 · Cited by 182 · see citing works

Central and peripheral effects of oxytocin administration in prairie voles (Microtus ochrogaster)

Witt, D. M., Carter, C. S., & Walton, D. M. (1990) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(90)90042-g · Cited by 181 · see citing works

Oxytocin stimulates lordosis behavior in female rats

Arletti, R., & Bertolini, A. (1985) · Neuropeptides · doi:10.1016/0143-4179(85)90095-2 · Cited by 179 · see citing works

Localization of chemical messengers in magnocellular neurons of the hypothalamic supraoptic and paraventricular nuclei: An immunohistochemical study using experimental manipulations

Meister, B., Villar, M. J., Ceccatelli, S., & Hökfelt, T. G. M. (1990) · Neuroscience · doi:10.1016/0306-4522(90)90094-k · Cited by 172 · see citing works

Sexual behavior increases c-fos expression in the forebrain of the male rat

Robertson, G. S., Pfaus, J. G., Atkinson, L. J., Matsumura, H., Phillips, A. G., & Fibiger, H. C. (1991) · Brain Research · doi:10.1016/0006-8993(91)91477-i · Cited by 169 · see citing works

Male Vole Urine Changes Luteinizing Hormone-Releasing Hormone and Norepinephrine in Female Olfactory Bulb

Dluzen, D. E., Ramirez, V. D., Carter, C. S., & Getz, L. L. (1981) · Science · doi:10.1126/science.7010608 · Cited by 167 · see citing works

Vasopressin and oxytocin: distribution and putative functions in the brain

Buijs, R. M., De Vries, G. J., Van Leeuwen, F. W., & Swaab, D. F. (1983) · Progress in Brain Research · doi:10.1016/s0079-6123(08)64379-4 · Cited by 167 · see citing works

Oxytocin and sexual behaviour in the male rat and rabbit

Stoneham, M. D., Everitt, B. J., Hansen, S., Lightman, S. L., & Todd, K. (1985) · Journal of Endocrinology · doi:10.1677/joe.0.1070097 · Cited by 160 · see citing works

Dose-response and time-response relationships between progesterone and the display of patterns of receptive and proceptive behavior in the female rat

Fadem, B. H., Barfield, R. J., & Whalen, R. E. (1979) · Hormones and Behavior · doi:10.1016/0018-506x(79)90033-3 · Cited by 160 · see citing works

Oxytocin improves male copulatory performance in rats

Arletti, R., Bazzani, C., Castelli, M., & Bertolini, A. (1985) · Hormones and Behavior · doi:10.1016/0018-506x(85)90002-9 · Cited by 155 · see citing works

Infusion of Antisense Oligo-deoxynucleotides to the Oxytocin Receptor in the Ventromedial Hypothalamus Reduces Estrogen-Induced Sexual Receptivity and Oxytocin Receptor Binding in the Female Rat

McCarthy, M. M., Kleopoulos, S. P., Mobbs, C. V., & Pfaff, D. W. (2008) · Neuroendocrinology · doi:10.1159/000126689 · Cited by 142 · see citing works

Oxytocin in the central nervous system and sexual behaviour in male rats

Hughes, A. M., Everitt, B. J., Lightman, S. L., & Todd, K. (1987) · Brain Research · doi:10.1016/0006-8993(87)91333-3 · Cited by 140 · see citing works

A Selective Oxytocin Antagonist Attenuates Progesterone Facilitation of Female Sexual Behavior

Witt, D. M., & Insel, T. R. (1991) · Endocrinology · doi:10.1210/endo-128-6-3269 · Cited by 138 · see citing works

Septal and Hippocampal Release of Vasopressin and Oxytocin during Late Pregnancy and Parturition in the Rat

Landgraf, R., Neumann, I. D., & Pittman, Q. J. (2008) · Neuroendocrinology · doi:10.1159/000125917 · Cited by 137 · see citing works

The neurohypophysis: Structure, function and control

Ganong, W. F. (1984) · Neuroscience · doi:10.1016/0306-4522(84)90189-1 · Cited by 132 · see citing works

Localized actions of progesterone in hypothalamus involve oxytocin.

Schumacher, M., Coirini, H., Frankfurt, M., & McEwen, B. S. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.17.6798 · Cited by 130 · see citing works

Oxytocin in Maternal, Sexual, and Social Behaviors

Pedersen, C. A., Caldwell, J. D., Jirikowski, G. F., & Insel, T. R. (1992) · Medical Entomology and Zoology · Cited by 125 · see citing works

Projections of the paraventricular nucleus of the hypothalamus to the sexually dimorphic lumbosacral region of the spinal cord

Wagner, C. K., & Clemens, L. G. (1991) · Brain Research · doi:10.1016/0006-8993(91)91629-f · Cited by 121 · see citing works

Topography of the oxytocin receptor system in rat brain: an autoradiographical study with a selective radioiodinated oxytocin antagonist.

Elands, J., Beetsma, A. L., Barberis, C., & de Kloet, E. R. (1988) · PubMed · Cited by 121 · see citing works

Postpartum Increases in Brain Oxytocin Binding

Insel, T. R. (2008) · Neuroendocrinology · doi:10.1159/000124694 · Cited by 116 · see citing works

Estradiol induces oxytocin binding sites in rat hypothalamic ventromedial nucleus

de Kloet, E. R., Voorhuis, T. A. M., & Elands, J. (1985) · European Journal of Pharmacology · doi:10.1016/0014-2999(85)90679-x · Cited by 116 · see citing works

Estradiol influences oxytocin-immunoreactive brain systems

Jirikowski, G. F., Caldwell, J. D., Pedersen, C. A., & Stumpf, W. E. (1988) · Neuroscience · doi:10.1016/0306-4522(88)90022-x · Cited by 111 · see citing works

Medial preoptic area oxytocin and female sexual receptivity.

Caldwell, J. D., Jirikowski, G. F., Greer, E. R., & Pedersen, C. A. (1989) · Behavioral Neuroscience · doi:10.1037//0735-7044.103.3.655 · Cited by 110 · see citing works

Oxytocin Activation of Maternal Behavior in the Rata

Pedersen, C. A., Caldwell, J. D., Peterson, G. W., Walker, C. H., & Mason, G. (1992) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1992.tb34346.x · Cited by 106 · see citing works

Induction of FOS Immunoreactivity in Oxytocin Neurons after Sexual Activity in Female Rats

Flanagan‐Cato, L. M., Pfaus, J. G., Pfaff, D. W., & McEwen, B. S. (2008) · Neuroendocrinology · doi:10.1159/000126562 · Cited by 103 · see citing works

Mating behavior induces selective expression of Fos protein within the chemosensory pathways of the male Syrian hamster brain

Kollack, S. S., & Newman, S. W. (1992) · Neuroscience Letters · doi:10.1016/0304-3940(92)90270-h · Cited by 102 · see citing works

Increased Fos Expression in Oxytocin Neurons Following Masculine Sexual Behavior

Witt, D. M., & Insel, T. R. (1994) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.1994.tb00549.x · Cited by 102 · see citing works

Oxytocin-induced facilitation of lordosis behaviour in rats is progesterone-dependent

Gorzalka, B. B. (1987) · Neuropeptides · doi:10.1016/0143-4179(87)90089-8 · Cited by 97 · see citing works

Anatomical Localization of the Effects of 17β-Estradiol on Oxytocin Receptor Binding in the Ventromedial Hypothalamic Nucleus*

Johnson, A. E., Coirini, H., Ball, G. F., & McEwen, B. S. (1989) · Endocrinology · doi:10.1210/endo-124-1-207 · Cited by 94 · see citing works

Medial preoptic area oxytocin and female sexual receptivity.

Caldwell, J. D., Jirikowski, G. F., Greer, E. R., et al. (1989) · Behavioral Neuroscience · doi:10.1037/0735-7044.103.3.655 · Cited by 92 · see citing works

Oxytocin Receptor Binding in Female Prairie Voles: Endogenous and Exogenous Oestradiol Stimulation

Witt, D. M., Carter, C. S., & Lnsel, T. R. (1991) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.1991.tb00258.x · Cited by 91 · see citing works

Time Course of the Estradiol-Dependent Induction of Oxytocin Receptor Binding in the Ventromedial Hypothalamic Nucleus of the Rat*

Johnson, A. E., Ball, G. F., Coirini, H., Harbaugh, C. R., McEwen, B. S., & Insel, T. R. (1989) · Endocrinology · doi:10.1210/endo-125-3-1414 · Cited by 87 · see citing works

Estrogen Alters Oxytocin mRNA Levels in the Preoptic Area

Caldwell, J. D., Brooks, P. J., Jirikowski, G. F., Barakat, A. S., Lund, P. K., & Pedersen, C. A. (1989) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.1989.tb00115.x · Cited by 84 · see citing works

Hormonal correlates of sexual behavior and ovulation in male-induced and postpartum estrus in female prairie voles

Carter, C. S., Witt, D. M., Manock, S. R., Adams, K. A., Bahr, J. M., & Carlstead, K. (1989) · Physiology & Behavior · doi:10.1016/0031-9384(89)90195-9 · Cited by 79 · see citing works

Males increase serum estrogen and estrogen receptor binding in brain of female voles

Cohen-Parsons, M., & Carter, C. S. (1987) · Physiology & Behavior · doi:10.1016/0031-9384(87)90227-7 · Cited by 77 · see citing works

Ovarian steroids and sexual interaction alter oxytocinergic content and distribution in the basal forebrain

Caldwell, J. D., Jirikowski, G. F., Greer, E. R., Stumpf, W. E., & Pedersen, C. A. (1988) · Brain Research · doi:10.1016/0006-8993(88)90882-7 · Cited by 76 · see citing works

Estradiol Modulation of Oxytocin Binding in the Ventromedial Hypothalamic Nucleus of Male and Female Rats

Coirini, H., Johnson, A. E., & McEwen, B. S. (2008) · Neuroendocrinology · doi:10.1159/000125221 · Cited by 71 · see citing works

Oxytocin and neurophysin in plasma and CSF during suckling in the guinea-pig

Robinson, I. C. A. F., & Jones, P. M. (2008) · Neuroendocrinology · doi:10.1159/000123278 · Cited by 69 · see citing works

MILK-EJECTION ACTIVITY (OXYTOCIN) IN PERIPHERAL VENOUS BLOOD IN MAN DURING LACTATION AND IN ASSOCIATION WITH COITUS

FOX, C. A., & Knaggs, G. S. (1969) · Journal of Endocrinology · doi:10.1677/joe.0.0450145 · Cited by 69 · see citing works

Infusion of an Oxytocin Antagonist into the Medial Preoptic Area Prior to Progesterone Inhibits Sexual Receptivity and Increases Rejection in Female Rats

Caldwell, J. D., Johns, J. M., Faggin, B. M., Senger, M., & Pendersen, C. A. (1994) · Hormones and Behavior · doi:10.1006/hbeh.1994.1024 · Cited by 63 · see citing works

Homologous regulation of brain oxytocin receptors.

Insel, T. R., Winslow, J. T., & Witt, D. M. (1992) · Endocrinology · doi:10.1210/endo.130.5.1315251 · Cited by 63 · see citing works

Oxytocin determination by radioimmunoassay in cattle. II. Effect of mating and stimulation of the genital tract in bulls, cows and heifers.

Schams, D., Baumann, G., & Leidl, W. (1982) · PubMed · Cited by 61 · see citing works

Oxytocin effects on lordosis frequency and lordosis duration following infusion into the medial pre-optic area and ventromedial hypothalamus of female rats

Schulze, H. G., & Gorzalka, B. B. (1991) · Neuropeptides · doi:10.1016/0143-4179(91)90008-7 · Cited by 60 · see citing works

Correlation between oxytocin neuronal sensitivity and oxytocin receptor binding: an electrophysiological and autoradiographical study comparing rat and guinea pig hippocampus.

Raggenbass, M., Tribollet, E., Dubois‐Dauphin, M., & Dreifuss, J. J. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.2.750 · Cited by 59 · see citing works

Patterns of behaviour during postpartum oestrus in prairie voles, Microtus ochrogaster

Witt, D. M., Carter, C. S., Chayer, R. P., & Adams, K. L. (1990) · Animal Behaviour · doi:10.1016/s0003-3472(05)80418-x · Cited by 59 · see citing works

Sexual and social interactions preceding and during male-induced oestrus in prairie voles, Microtus ochrogaster

Witt, D. M., Carter, C. S., Carlstead, K., & Read, L. D. (1988) · Animal Behaviour · doi:10.1016/s0003-3472(88)80217-3 · Cited by 54 · see citing works

BLOOD LEVELS OF OXYTOCIN IN THE FEMALE GOAT DURING COITUS AND IN RESPONSE TO STIMULI ASSOCIATED WITH MATING

McNeilly, A. S., & DUCKER, H. A. (1972) · Journal of Endocrinology · doi:10.1677/joe.0.0540399 · Cited by 52 · see citing works

Oxytocin inhibits male sexual behavior in prairie voles

Mahalati, K., Okanoya, K., Witt, D. M., & Carter, C. S. (1991) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(91)90426-3 · Cited by 51 · see citing works

THE EFFECT OF SYNTHETIC OXYTOCIN UPON SEMINAL CHARACTERISTICS AND SEXUAL BEHAVIOUR IN MALE RABBITS

FJELLSTROM, D., Kihlström, J. E., & Melin, P. (1968) · Reproduction · doi:10.1530/jrf.0.0170207 · Cited by 48 · see citing works

Influence of Oxytocin on Sexual Behavior in Male Rabbits

Melin, P., & Kihlström, J. E. (1963) · Endocrinology · doi:10.1210/endo-73-4-433 · Cited by 43 · see citing works

OUTPUT OF SPERMATOZOA AND FLUID BY THE TESTIS OF THE RAM AND ITS RESPONSE TO OXYTOCIN

Voglmayr, J. K. (1975) · Reproduction · doi:10.1530/jrf.0.0430119 · Cited by 42 · see citing works

Testosterone Modulates Oxytocin Binding in the Hypothalamus of Castrated Male Rats

Johnson, A. E., Coirini, H., McEwen, B. S., & Insel, T. R. (2008) · Neuroendocrinology · doi:10.1159/000125222 · Cited by 40 · see citing works

SHORT- AND LONG-TERM EFFECTS OF OXYTOCIN ON QUALITY AND QUANTITY OF SEMEN FROM RAMS

Knight, T. W., & Lindsay, D. R. (1970) · Reproduction · doi:10.1530/jrf.0.0210523 · Cited by 39 · see citing works

Evidence for a colocalization of oxytocin mRNA and galanin in magnocellular hypothalamic neurons: a study combining in situ hybridization and immunohistochemistry

Landry, M., Trembleau, A., Arai, R., & Calas, A. (1991) · Molecular Brain Research · doi:10.1016/0169-328x(91)90060-b · Cited by 39 · see citing works

Neurobiology of Oxytocin

(1986) · Current topics in neuroendocrinology · doi:10.1007/978-3-642-70414-7 · Cited by 38 · see citing works

Sex Differences in the Regulation of Oxytocin Receptors by Ovarian Steroids in the Ventromedial Hypothalamus of the Rat

Coirini, H., Johnson, A. E., Schumacher, M., & McEwen, B. S. (2008) · Neuroendocrinology · doi:10.1159/000126125 · Cited by 37 · see citing works

EFFECTS OF MATING ON LEVELS OF OXYTOCIN AND PROLACTIN IN THE PLASMA OF MALE AND FEMALE RABBITS

Fuchs, A., CUBILE, L., & Dawood, M. (1981) · Journal of Endocrinology · doi:10.1677/joe.0.0900245 · Cited by 36 · see citing works

Effects of nonapeptide antagonists on oxytocin- and arginine-vasopressin-induced analgesia in mice

Caldwell, J. D., Mason, G., Stanley, D. A., Jerdack, G. R., Hruby, V. J., Hill, P. S., Prange, A. J., & Pedersen, C. A. (1987) · Regulatory Peptides · doi:10.1016/0167-0115(87)90011-5 · Cited by 33 · see citing works

The biology of social bonding in a monogamous mammal

Witt, D., Williams, J. F., & Porges, C. C. (1989) · Cited by 30 · see citing works

Oxytocin determination by radioimmunoassay in cattle

Schams, D., Baumann, G., & Leidl, W. (1982) · European Journal of Endocrinology · doi:10.1530/acta.0.0990218 · Cited by 30 · see citing works

Males increase progestin receptor binding in brain of female voles

Cohen-Parsons, M., & Carter, C. S. (1988) · Physiology & Behavior · doi:10.1016/0031-9384(88)90297-1 · Cited by 26 · see citing works

Social stimuli augment estrogen receptor binding in preoptic area of female prairie voles

Cohen-Parsons, M., & Roy, E. J. (1989) · Brain Research · doi:10.1016/0006-8993(89)91260-2 · Cited by 23 · see citing works

Biosynthesis of Oxytocin in the Brain and Peripheral Organs

Ivell, R. (1986) · Current topics in neuroendocrinology · doi:10.1007/978-3-642-70414-7_1 · Cited by 20 · see citing works

Central Oxytocin Antagonism Decreases Female Reproductive Behavior

Witt, D. M., & Insel, T. R. (1992) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1992.tb34379.x · Cited by 11 · see citing works

The oxytocin receptor system: structure, function, and regulation

Gimpl, G., & Fahrenholz, F. (2001) · Physiological Reviews · doi:10.1152/physrev.2001.81.2.629 · Cited by 3,089 · see citing works

The neurobiology of attachment

Insel, T. R., & Young, L. J. (2001) · Nature Reviews Neuroscience · doi:10.1038/35053579 · Cited by 1,173 · see citing works

Oxytocin: The Great Facilitator of Life

Lee, H.-J., Macbeth, A. H., Pagani, J., & Young, W. S. (2009) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2009.04.001 · Cited by 1,037 · see citing works

The neurobiology and control of anxious states

Millan, M. J. (2003) · Progress in Neurobiology · doi:10.1016/s0301-0082(03)00087-x · Cited by 963 · see citing works

a neurobehavioral model of affiliative bonding: implications for conceptualizing a human trait of affiliation

depue, R. A., & morrone-strupinsky, J. V. (2005) · Behavioral and Brain Sciences · doi:10.1017/s0140525x05000063 · Cited by 958 · see citing works

Social behavior functions and related anatomical characteristics of vasotocin/vasopressin systems in vertebrates

Goodson, J. L., & Bass, A. H. (2001) · Brain Research Reviews · doi:10.1016/s0165-0173(01)00043-1 · Cited by 632 · see citing works

HOW THE BRAIN PROCESSES SOCIAL INFORMATION: Searching for the Social Brain

Insel, T. R., & Fernald, R. D. (2004) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.27.070203.144148 · Cited by 556 · see citing works

A neurobiological basis of social attachment.

(1997) · American Journal of Psychiatry · doi:10.1176/ajp.154.6.726 · Cited by 553 · see citing works

Oxytocin, motherhood and bonding

Kendrick, K. M. (2000) · Experimental Physiology · doi:10.1111/j.1469-445x.2000.tb00014.x · Cited by 378 · see citing works

Male Sexual Behavior

Hull, E. M., & Rodrı́guez–Manzo, G. (2009) · Elsevier eBooks · doi:10.1016/b978-008088783-8.00001-2 · Cited by 371 · see citing works

Neuropeptides and the evolution of social behavior

Insel, T. (2000) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(00)00146-x · Cited by 264 · see citing works

Sexual motivation—an inquiry into events determining the occurrence of sexual behavior

Ågmo, A. (1999) · Behavioural Brain Research · doi:10.1016/s0166-4328(99)00088-1 · Cited by 236 · see citing works

Nonapeptides and the evolutionary patterning of sociality

GOODSON, J. (2008) · Progress in brain research · doi:10.1016/s0079-6123(08)00401-9 · Cited by 228 · see citing works

Menstrual cycle-related changes in plasma oxytocin are relevant to normal sexual function in healthy women

Salonia, A., Nappi, R. E., Pontillo, M., Daverio, R., Smeraldi, A., Briganti, A., Fabbri, F., Zanni, G. E., Rigatti, P., & Montorsi, F. (2004) · Hormones and Behavior · doi:10.1016/j.yhbeh.2004.10.002 · Cited by 229 · see citing works

Oxytocin, vasopressin, and autism: Is there a connection?

Insel, T. R., O’Brien, D. J., & Leckman, J. F. (1999) · Biological Psychiatry · doi:10.1016/s0006-3223(98)00142-5 · Cited by 226 · see citing works

Neurofunctional mechanisms in autism

Waterhouse, L., Fein, D., & Modahl, C. (1996) · Psychological Review · doi:10.1037/0033-295x.103.3.457 · Cited by 218 · see citing works

Chronic and acute intranasal oxytocin produce divergent social effects in mice

Huang, H., Michetti, C., Busnelli, M., Managò, F., Sannino, S., Scheggia, D., Giancardo, L., Sona, D., Murino, V., Chini, B., et al. (2014) · Neuropsychopharmacology · doi:10.1038/npp.2013.310 · Cited by 199 · see citing works

Oxytocin, Vasopressin, and the Neuroendocrine Basis of Pair Bond Formation

Insel, T. R., Winslow, J. T., Wang, Z., & Young, L. J. (1998) · Advances in experimental medicine and biology · doi:10.1007/978-1-4615-4871-3_28 · Cited by 170 · see citing works

Female oxytocin gene-knockout mice, in a semi-natural environment, display exaggerated aggressive behavior

Ragnauth, A. K., Devidze, N., Moy, V., Finley, K., Goodwillie, A., Kow, L. ‐., Muglia, L. J., & Pfaff, D. W. (2005) · Genes, Brain and Behavior · doi:10.1111/j.1601-183x.2005.00118.x · Cited by 160 · see citing works

Neurobiology of Male Sexual Behavior

Hull, E. M., Wood, R. W., & MCKENNA, K. (2006) · Elsevier eBooks · doi:10.1016/b978-012515400-0/50038-5 · Cited by 149 · see citing works

Peripherally administered non-peptide oxytocin antagonist, L368,899®, accumulates in limbic brain areas: A new pharmacological tool for the study of social motivation in non-human primates

Boccia, M. L., Goursaud, A.-P. S., Bachevalier, J., Anderson, K. D., & Pedersen, C. A. (2007) · Hormones and Behavior · doi:10.1016/j.yhbeh.2007.05.009 · Cited by 136 · see citing works

Hypothalamic Paraventricular Nucleus Modulates Maternal Aggression in Rats: Effects of Ibotenic Acid Lesion and Oxytocin Antisense

Giovenardi, M., Padoin, M. J., Cadore, L. P., & Lucion, A. B. (1998) · Physiology & Behavior · doi:10.1016/s0031-9384(97)00434-4 · Cited by 135 · see citing works

Putative isotocin distributions in sonic fish: Relation to vasotocin and vocal–acoustic circuitry

Goodson, J. L., Evans, A. K., & Bass, A. H. (2003) · The Journal of Comparative Neurology · doi:10.1002/cne.10679 · Cited by 126 · see citing works

Effects of central vasotocin and mesotocin manipulations on social behavior in male and female zebra finches

Goodson, J. L., Lindberg, L., & Johnson, P. (2004) · Hormones and Behavior · doi:10.1016/j.yhbeh.2003.08.006 · Cited by 115 · see citing works

Serotonin and neuropeptides in affiliative behaviors

Insel, T. R., & Winslow, J. T. (1998) · Biological Psychiatry · doi:10.1016/s0006-3223(98)00094-8 · Cited by 105 · see citing works

Male Sexual Behavior

Hull, E. M., Meisel, R. L., & Sachs, B. D. (2002) · Elsevier eBooks · doi:10.1016/b978-012532104-4/50003-2 · Cited by 102 · see citing works

Central nervous system actions of oxytocin and modulation of behavior in humans

McCarthy, M. M., & Altemus, M. M. (1997) · Molecular Medicine Today · doi:10.1016/s1357-4310(97)01058-7 · Cited by 88 · see citing works

Progress and promise for the MDMA drug development program

Feduccia, A. A., Holland, J. A., & Mithoefer, M. C. (2017) · Psychopharmacology · doi:10.1007/s00213-017-4779-2 · Cited by 78 · see citing works

Effects of different sexual stimuli on oxytocin release, uterine activity and receptive behavior in estrous sows

Langendijk, P., Bouwman, E. G., Schams, D., Soede, N. M., & Kemp, B. (2003) · Theriogenology · doi:10.1016/s0093-691x(02)01157-3 · Cited by 70 · see citing works

Targeted Reduction of Oxytocin Expression Provides Insights into its Physiological Roles

Young, W. S., Shepard, E. A., DeVries, A. C., Zimmer, A., LaMarca, M. E., Ginns, E. I., Amico, J. A., Nelson, R. J., Hennighausen, L. G., & Wagner, K. (1998) · Advances in experimental medicine and biology · doi:10.1007/978-1-4615-4871-3_30 · Cited by 51 · see citing works

Effects of neonatal oxytocin manipulations on male reproductive potential in prairie voles

BALES, K., ABDELNABI, M., CUSHING, B., OTTINGER, M., & CARTER, C. (2004) · Physiology &amp; Behavior · doi:10.1016/j.physbeh.2004.02.016 · Cited by 47 · see citing works

A sexual arousability model involving steroid effects at the plasma membrane

Caldwell, J. D. (2002) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(01)00035-5 · Cited by 44 · see citing works

Regulatory Mechanisms of Oxytocin‐Mediated Sociosexual Behavior

Witt, D. M. (1997) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1997.tb51927.x · Cited by 45 · see citing works

Effects of Stroking on Salivary Oxytocin and Cortisol in Guide Dogs: Preliminary Results

Ogi, A., Mariti, C., Baragli, P., Sergi, V., & Gazzano, A. (2020) · Animals · doi:10.3390/ani10040708 · Cited by 43 · see citing works

Social buffering of stress – Physiological and ethological perspectives

Wu, A. (2021) · Applied Animal Behaviour Science · doi:10.1016/j.applanim.2021.105325 · Cited by 39 · see citing works

Molecular approaches to aggregation behavior and social attachment

de Bono, M. (2002) · Journal of Neurobiology · doi:10.1002/neu.10162 · Cited by 36 · see citing works

Oxytocin modulates social interaction but is not essential for sexual behavior in male mice

Lazzari, V. M., Becker, R. O., de Azevedo, M. S., Morris, M., Rigatto, K., Almeida, S., Lucion, A. B., & Giovenardi, M. (2013) · Behavioural Brain Research · doi:10.1016/j.bbr.2013.01.025 · Cited by 38 · see citing works

Social and sexual incentive properties of estrogen receptor α, estrogen receptor β, or oxytocin knockout mice

Ågmo, A., Choleris, E., Kavaliers, M., Pfaff, D. W., & Ogawa, S. (2007) · Genes Brain & Behavior · doi:10.1111/j.1601-183x.2007.00327.x · Cited by 34 · see citing works

Day length and sociosexual cohabitation alter central oxytocin receptor binding in female meadow voles (Microtus pennsylvanicus).

Parker, K. J., Phillips, K. M., Kinney, L. F., & Lee, T. M. (2001) · Behavioral Neuroscience · doi:10.1037/0735-7044.115.6.1349 · Cited by 32 · see citing works

Peripheral oxytocin in female baboons relates to estrous state and maintenance of sexual consortships

Moscovice, L. R., & Ziegler, T. E. (2012) · Hormones and Behavior · doi:10.1016/j.yhbeh.2012.08.011 · Cited by 31 · see citing works

Injection of Oxytocin into the Medial Preoptic–Anterior Hypothalamus Increases Ultrasound Production by Female Hamsters

Floody, O. R., Cooper, T. T., & Albers, H. E. (1998) · Peptides · doi:10.1016/s0196-9781(98)00029-1 · Cited by 31 · see citing works

Identifying Context-Specific Gene Profiles of Social, Reproductive, and Mate Preference Behavior in a Fish Species with Female Mate Choice

Ramsey, M. E., Maginnis, T. L., Wong, R. Y., Brock, C. D., & Cummings, M. E. (2012) · Frontiers in Neuroscience · doi:10.3389/fnins.2012.00062 · Cited by 30 · see citing works

Sexual behavior and dendritic spine density of posterodorsal medial amygdala neurons in oxytocin knockout female mice

Becker, R. O., Lazzari, V. M., Menezes, I. C., Morris, M., Rigatto, K., Lucion, A. B., Rasia‐Filho, A. A., & Giovenardi, M. (2013) · Behavioural Brain Research · doi:10.1016/j.bbr.2013.07.034 · Cited by 21 · see citing works

Perinatal exposure to organohalogen pollutants decreases vasopressin content and its mRNA expression in magnocellular neuroendocrine cells activated by osmotic stress in adult rats

Mucio-Ramírez, S., Sánchez-Islas, E., Sánchez‐Jaramillo, E., Currás‐Collazo, M., Juárez-González, V. R., Alvarez-Gonzalez, M. Y., Orser, L. E., Hou, B., Pellicer, F., Kodavanti, P. R. S., et al. (2017) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2017.05.039 · Cited by 19 · see citing works

Using transgenic mouse models to study oxytocin's role in the facilitation of species propagation

Lee, H., Pagani, J. H., & Young, W. S. (2010) · Brain Research · doi:10.1016/j.brainres.2010.08.042 · Cited by 19 · see citing works

A CCKA-Receptor Antagonist Administered to the Neonate Alters Mother–Infant Interactions in the Rat

Weller, A., & Dubson, L. (1998) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(97)00530-3 · Cited by 18 · see citing works

Prospects for Exploring the Molecular-Genomic Foundations of Therapeutic Hypnosis with DNA Microarrays

Rossi, E. L. (2005) · American Journal of Clinical Hypnosis · doi:10.1080/00029157.2005.10401514 · Cited by 15 · see citing works

Male Carollia perspicillata bats call more than females in a distressful context

González‐Palomares, E., López‐Jury, L., Wetekam, J., Kiai, A., García‐Rosales, F., & Hechavarría, J. C. (2021) · Royal Society Open Science · doi:10.1098/rsos.202336 · Cited by 11 · see citing works

Neurochemistry of Male Sexual Behavior

Hull, E. M., Dominguez, J. M., & Muschamp, J. W. (2006) · Springer eBooks · doi:10.1007/978-0-387-30405-2_2 · Cited by 12 · see citing works

Prenatal undernutrition suppresses sexual behavior in female rats

Matsuzaki, T., Munkhzaya, M., Iwasa, T., Tungalagsuvd, A., Yano, K., Mayila, Y., Yanagihara, R., Tokui, T., Kato, T., Kuwahara, A., et al. (2018) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2018.08.013 · Cited by 10 · see citing works

Behavioral Neuroendocrinology of Reproduction in Mammals

Park, J., & Rissman, E. F. (2011) · Elsevier eBooks · doi:10.1016/b978-0-12-374928-4.10008-2 · Cited by 10 · see citing works

Neuroregulatory Peptides of Central Nervous System Origin: From Laboratory to Clinic

Geracioti, T. D., Strawn, J. R., Ekhator, N. N., Wortman, M. D., & Kasckow, J. W. (2009) · Elsevier eBooks · doi:10.1016/b978-008088783-8.00082-6 · Cited by 10 · see citing works

Decreases in calmodulin binding proteins and calmodulin dependent protein phosphorylation in the medial preoptic area at the onset of maternal behavior in the rat

O’Day, D. H., Lydan, M. A., Watchus, J., & Fleming, A. S. (2001) · Journal of Neuroscience Research · doi:10.1002/jnr.1112 · Cited by 5 · see citing works

The influence of manual semen collection in male trained dogs (Canis familiaris), in the presence or absence of a female in estrus, on the concentrations of cortisol, oxytocin, prolactin and testosterone

Woszczyło, M., Szumny, A. J., Knap, P., Jezierski, T. A., Niżański, W., Kokocińska, A., Skwark, M. J., & Dzięcioł, M. (2023) · PLoS ONE · doi:10.1371/journal.pone.0278524 · Cited by 4 · see citing works

Phenotypic Expression of an Oxytocin Peptide Null Mutation in Mice

Winslow, J., Young, L. J., Hearn, E. F., Gingrich, B., Wang, Z., Guo, Q., Matzuk, M. M., & Insel, T. R. (1998) · Advances in experimental medicine and biology · doi:10.1007/978-1-4615-4871-3_31 · Cited by 4 · see citing works

Heterosexual Interactions Promote Oxytocin Secretion in Sexually Naive, but Not Experienced, Male Wistar Ratsa

Hillegaart, V., Alster, P., Uvnäs‐Moberg, K., & Ahlénius, S. (1997) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1997.tb51959.x · Cited by 3 · see citing works

Behavioral Neuroendocrinology of Reproduction in Mammals

Park, J., & Rissman, E. F. (2011) · Elsevier eBooks · doi:10.1016/b978-0-12-374932-1.00055-x · Cited by 2 · see citing works

Neuroregulatory Peptides of Central Nervous System Origin

Kasckow, J., & Geracioti, T. D. (2002) · Elsevier eBooks · doi:10.1016/b978-012532104-4/50091-3 · Cited by 1 · see citing works

Oxytocin Gene and Peptide Analysis in Children with Autism: A Preliminary Case Study

Grunwald, W. C., Morris, M., Klykylo, W. M., & Cool, D. R. (2015) · Medical Research Archives · doi:10.18103/mra.v0i1.19

Development of G-quadruplex Stabilizers as Anticancer Drug Therapy and Selective Agonists of the Human Oxytocin Receptor as a Therapeutic Tool for Neuropsychiatric Disorders

Sassano, M. F. (2019) · Carolina Digital Repository (University of North Carolina at Chapel Hill) · doi:10.17615/wwr3-7m34

The Neuroendocrine and Cardiovascular Responses to a Pup in Male Prairie Voles (M. ochrogaster)

Kenkel, W. M. (2013) · Figshare

Neuroendocrinology of reproductive behavior

Chiang, V. S., & Park, J. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-15986-2.00015-0

Inhibition tunes prefrontal circuit dynamics to promote sociosexual behavior in female micePreprint

Amadei, E. A., Aceituno, P. V., Loidl, R., Boehringer, R., Morsch, E. S., Ehret, B., & Grewe, B. F. (2026) · eLife · doi:10.7554/elife.112102.1

Inhibition tunes prefrontal circuit dynamics to promote sociosexual behavior in female micePreprint

Amadei, E. A., Aceituno, P. V., Loidl, R., Boehringer, R., Morsch, E. S., Ehret, B., & Grewe, B. F. (2026) · eLife · doi:10.7554/elife.112102

Oxytocin and Vasopressin Receptors and Species-Typical Social Behaviors

Young, L. J. (1999) · Hormones and Behavior · doi:10.1006/hbeh.1999.1548 · Cited by 211 · see citing works

An oxytocin receptor gene polymorphism is associated with distinct neural responses to mating encounters in male prairie voles

King, L. B., Walum, H., Xiao, Y., Caslin, A. Y., Haddad, F. C., Young, L. J., & Johnson, Z. V. (2025) · Hormones and Behavior · doi:10.1016/j.yhbeh.2025.105761 · Cited by 1 · see citing works

Examination of oxytocin receptor distribution and social behavior across a South American rodent clade

Kamal, Y. (2014) · Smith ScholarWorks (Smith College)

Gene targeting approaches to neuroendocrinology: oxytocin, maternal behavior, and affiliation

Young, L. J., Winslow, J. T., Wang, Z., Gingrich, B., Guo, Q., Matzuk, M. M., & Insel, T. R. (1997) · Hormones and Behavior · doi:10.1006/hbeh.1997.1377 · Cited by 105 · see citing works

Neonatal oxytocin manipulations have long-lasting, sexually dimorphic effects on vasopressin receptors

Bales, K. L., Plotsky, P. M., Young, L. J., Lim, M. M., Grotte, N., Ferrer, E., & Carter, C. S. (2007) · Neuroscience · doi:10.1016/j.neuroscience.2006.09.009 · Cited by 150 · see citing works