Neuropeptides and the evolution of social behavior
Abstract
Comparative studies over the past year have revealed two new insights into the role of neuropeptides in the evolution of social behaviors. First, across vertebrate taxa, certain neuropeptide effects appear to be gender-specific. Second, species variations in receptor gene structure can alter neuropeptide receptor distribution and thereby contribute to species differences in social behavior.
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The behavioral effects of OT are evolutionary conserved.
“we believe the behavioral effects of OT are indeed evolutionary conserved (6, 32)”
From Statistical and Methodological Considerations for the Interpretation of Intranasal Oxytocin Studies (2016) · cites this paper as [32]
Oxytocin has central neuromodulatory effects on social behaviors such as affiliative, aggressive, and parental behaviors.
“Oxytocin is a mammalian neurohormone composed of nine amino acids, known for its peripheral effects on parturition and lactation (5–7), as well as its central neuromodulatory effects on social behaviors such as affiliative, aggressive, and parental behaviors (8, 9).”
From Oxytocin during Development: Possible Organizational Effects on Behavior (2015) · cites this paper as [8]
Oxytocin neurons in the PVH regulate a range of social behaviors, from parental care to social recognition of conspecifics.
“which are known to regulate a range of social behaviors, from parental care to social recognition of conspecifics (13-18).”
From Social Interaction Elicits Activity in Glutamatergic Neurons in the Posterior Intralaminar Complex of the Thalamus (2024) · cites this paper as [17]
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- Authors
- Insel, T.
- Affiliations
- Emory University (US)
- Corresponding author
- Insel, T
- ORCID
- Insel, T
- Venue
- Current Opinion in Neurobiology
- Publisher
- Elsevier BV
- Published
- 2000-12-01
- Volume
- 10
- Issue
- 6
- Pages
- 784-789
- ISSN
- 0959-4388 (ISSN-L)
- OpenAlex
- W1984942603
- Cited by
- 264
- References
- 33
- Citations by year
- 2026: 4 · 2025: 3 · 2024: 6 · 2023: 9 · 2022: 10 · 2021: 8 · 2020: 10 · 2019: 11 · 2018: 11 · 2017: 15 · 2016: 9 · 2015: 12 · 2014: 15 · 2013: 17 · 2012: 11
- FWCI
- 10.97
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Current Opinion in Neurobiology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Mental Health (MH-56539, MH 56897)
- Topics
- Social Sciences › Psychology › Social Psychology › Neuroendocrine regulation and behavior
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuropeptides and Animal Physiology
- Life Sciences › Agricultural and Biological Sciences › Ecology, Evolution, Behavior and Systematics › Animal Behavior and Reproduction
- Keywords
- neuropeptides, evolution of social behavior, sex differences, neuropeptide receptors, receptor gene structure, vertebrates
- MeSH terms
- Animals, Brain Chemistry, Biological Evolution, Neuropeptides, Social Behavior
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