Development of a mouse test for repetitive, restricted behaviors: Relevance to autism
Open accessAbstract
Repetitive behavior, a core symptom of autism, encompasses stereotyped responses, restricted interests, and resistance to change. These studies investigated whether different components of the repetitive behavior domain could be modeled in the exploratory hole-board task in mice. Four inbred mouse strains, C57BL/6J, BALB/cByJ, BTBR T+tf/J, and FVB/NJ, and mice with reduced expression of Grin1, leading to NMDA receptor hypofunction (NR1neo/neo mice), were tested for exploration and preference for olfactory stimuli in an activity chamber with a 16-hole floor-board. Reduced exploration and high preference for holes located in the corners of the chamber were observed in BALB/cByJ and BTBR T+tf/J mice. All inbred strains had initial high preference for a familiar olfactory stimulus (clean cage bedding). BTBR T+tf/J was the only strain that did not demonstrate a shift in hole preference towards an appetitive olfactory stimulus (cereal or a chocolate chip), following home cage exposure to the food. The NR1neo/neo mice showed lower hole selectivity and aberrant olfactory stimulus preference, in comparison to wildtype controls. The results indicate that NR1neo/neo mice have repetitive nose poke responses that are less modified by environmental contingencies than responses in wildtype mice. 25-30% of NMDA receptor hypomorphic mice also show self-injurious responses. Findings from the olfactory studies suggest that resistance to change and restricted interests might be modeled in mice by a failure to alter patterns of hole preference following familiarization with an appetitive stimulus, and by high preference persistently demonstrated for one particular olfactory stimulus. Further work is required to determine the characteristics of optimal mouse social stimuli in the olfactory hole-board test.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Several naturally occurring inbred strains of mice display behavioral features that recapitulate diagnostic symptoms of neurodevelopmental disorders.
“Several naturally occurring inbred strains of mice display behavioral features that recapitulate diagnostic symptoms of neurodevelopmental disorders (59–70).”
From Negative allosteric modulation of the mGluR5 receptor reduces repetitive behaviors and rescues social deficits in mouse models of autism (2012) · cites this paper as [65]
C58/J mice display high levels of stereotyped vertical jumping behaviors relevant to the motor stereotypies of the third diagnostic symptom category of autism.
“C58/J (C58) is another commercially available inbred strain of mouse that displays high levels of stereotyped vertical jumping behaviors, relevant to the motor stereotypies of the third diagnostic symptom category of autism (65, 67).”
From Negative allosteric modulation of the mGluR5 receptor reduces repetitive behaviors and rescues social deficits in mouse models of autism (2012) · cites this paper as [65]
Cites
Diagnostic and Statistical Manual of Mental Disorders (DSM-IV)
Hu, R. J. (2003) · Elsevier eBooks · doi:10.1016/b0-12-226870-9/01070-4 · Cited by 9,167 · see citing works
A new one-trial test for neurobiological studies of memory in rats. 1: behavioral data
Ennaceur, A., & Delacour, J. (1988) · Behavioural Brain Research · doi:10.1016/0166-4328(88)90157-x · Cited by 3,223 · see citing works
The use of a plus-maze to measure anxiety in the mouse
Lister, R. G. (1987) · Psychopharmacology · doi:10.1007/bf00177912 · Cited by 2,617 · see citing works
Moy, S. S., Nadler, J. J., Perez, A., Barbaro, R. P., Johns, J. M., Magnuson, T. R., Piven, J., & Crawley, J. N. (2004) · Genes, Brain and Behavior · doi:10.1111/j.1601-1848.2004.00076.x · Cited by 1,545 · see citing works
Self-citationAltered synaptic plasticity in a mouse model of fragile X mental retardation
Huber, K. M., Gallagher, S. M., Warren, S. T., & Bear, M. F. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.122205699 · Cited by 1,349 · see citing works
Varieties of Repetitive Behavior in Autism: Comparisons to Mental Retardation
Bodfish, J. W., Symons, F. J., Parker, D. E., & Lewis, M. H. (2000) · Journal of Autism and Developmental Disorders · doi:10.1023/a:1005596502855 · Cited by 1,223 · see citing works
Self-citationMice with Reduced NMDA Receptor Expression Display Behaviors Related to Schizophrenia
Mohn, A. R., Gainetdinov, R. R., Caron, M. G., & Koller, B. H. (1999) · Cell · doi:10.1016/s0092-8674(00)81972-8 · Cited by 1,075 · see citing works
Self-citationEthologically-based animal models of anxiety disorders.
Lister, R. (1990) · Pharmacology and Therapeutics · doi:10.1016/0163-7258(90)90021-s · Cited by 894 · see citing works
Mouse behavioral tasks relevant to autism: Phenotypes of 10 inbred strains
MOY, S., NADLER, J., YOUNG, N., PEREZ, A., HOLLOWAY, L., BARBARO, R., BARBARO, J., WILSON, L., THREADGILL, D., & LAUDER, J. (2007) · Behavioural Brain Research · doi:10.1016/j.bbr.2006.07.030 · Cited by 776 · see citing works
Self-citationAutomated apparatus for quantitation of social approach behaviors in mice
Nadler, J. J., Moy, S. S., Dold, G., Trang, D., Simmons, N., Perez, A., Young, N. B., Barbaro, R. P., Piven, J., Magnuson, T. R., et al. (2004) · Genes, Brain and Behavior · doi:10.1111/j.1601-183x.2004.00071.x · Cited by 775 · see citing works
Self-citationExploratory behavior models of anxiety in mice
Crawley, J. N. (1985) · Neuroscience & Biobehavioral Reviews · doi:10.1016/0149-7634(85)90030-2 · Cited by 756 · see citing works
Self-citationAnnotation: Repetitive Behaviour in Autism: A Review of Psychological Research
Turner, M. (1999) · Journal of Child Psychology and Psychiatry · doi:10.1111/1469-7610.00502 · Cited by 688 · see citing works
Validity of head-dipping as a measure of exploration in a modified hole-board
File, S. E., & Wardill, A. G. (1975) · Psychopharmacology · doi:10.1007/bf00421184 · Cited by 670 · see citing works
Diffusion tensor imaging of the corpus callosum in Autism
Alexander, A. L., Lee, J. E., Lazar, M., Boudos, R., DuBray, M. B., Oakes, T. R., Miller, J. N., Lu, J. K., Jeong, E., McMahon, W. M., et al. (2006) · NeuroImage · doi:10.1016/j.neuroimage.2006.08.032 · Cited by 593 · see citing works
The use of behavioral test batteries: Effects of training history
McIlwain, K. L., Merriweather, M. Y., Yuva-Paylor, L. A., & Paylor, R. (2001) · Physiology & Behavior · doi:10.1016/s0031-9384(01)00528-5 · Cited by 579 · see citing works
MRI volumes of amygdala and hippocampus in non–mentally retarded autistic adolescents and adults
Aylward, E., Minshew, N. J., Goldstein, G., Honeycutt, N. A., Augustine, A. M., Yates, K. O., Barta, P. E., & Pearlson, G. D. (1999) · Neurology · doi:10.1212/wnl.53.9.2145 · Cited by 513 · see citing works
Genetic Heterogeneity Between the Three Components of the Autism Spectrum: A Twin Study
RONALD, A., HAPPÉ, F., BOLTON, P., BUTCHER, L. M., PRICE, T. S., WHEELWRIGHT, S., BARON-COHEN, S., & PLOMIN, R. (2006) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/01.chi.0000215325.13058.9d · Cited by 508 · see citing works
Hou, L., Antion, M. D., Hu, D., Spencer, C. M., Paylor, R., & Klann, E. (2006) · Neuron · doi:10.1016/j.neuron.2006.07.005 · Cited by 469 · see citing works
Evidence for a cerebellar role in reduced exploration and stereotyped behavior in autism
Pierce, K., & Courchesne, E. (2001) · Biological Psychiatry · doi:10.1016/s0006-3223(00)01008-8 · Cited by 464 · see citing works
Takeda, H., Tsuji, M., & Matsumiya, T. (1998) · European Journal of Pharmacology · doi:10.1016/s0014-2999(98)00223-4 · Cited by 461 · see citing works
Differences in fear motivated behaviors among inbred mouse strains
Trullás, R., & Skolnick, P. (1993) · Psychopharmacology · doi:10.1007/bf02244948 · Cited by 451 · see citing works
Brain anatomy and sensorimotor gating in Asperger's syndrome
McAlonan, G. M. (2002) · Brain · doi:10.1093/brain/awf150 · Cited by 447 · see citing works
Factors controlling measures of anxiety and responses to novelty in the mouse
File, S. E. (2001) · Behavioural Brain Research · doi:10.1016/s0166-4328(01)00292-3 · Cited by 437 · see citing works
Repetitive Behavior Profiles in Asperger Syndrome and High-Functioning Autism
South, M., Ozonoff, S., & McMahon, W. M. (2005) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-004-1992-8 · Cited by 423 · see citing works
Griebel, G., Belzung, C., Perrault, G., & Sanger, D. J. (2000) · Psychopharmacology · doi:10.1007/s002130050038 · Cited by 420 · see citing works
Sensorimotor gating deficits in adults with autism
Perry, W., Minassian, A., Lopez, B., Maron, L., & Lincoln, A. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.09.025 · Cited by 352 · see citing works
Hippocampal synaptic plasticity is impaired in the Mecp2-null mouse model of Rett syndrome
Asaka, Y., Jugloff, D. G. M., Zhang, L., Eubanks, J. H., & Fitzsimonds, R. M. (2005) · Neurobiology of Disease · doi:10.1016/j.nbd.2005.07.005 · Cited by 341 · see citing works
An MRI study of the corpus callosum in autism
Piven, J., Bailey, J. M., Ranson, B. J., & Arndt, S. V. (1997) · American Journal of Psychiatry · doi:10.1176/ajp.154.8.1051 · Cited by 338 · see citing works
Investigating the structure of the restricted, repetitive behaviours and interests domain of autism
Szatmári, P., Georgiades, S., Bryson, S. E., Zwaigenbaum, L., Roberts, W., Mahoney, W. J., Goldberg, J., & TUFF, L. (2005) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2005.01537.x · Cited by 311 · see citing works
Cuccaro, M. L., Shao, Y., Grubber, J., Slifer, M., Wolpert, C. M., Donnelly, S. L., Abramson, R. K., Ravan, S. A., Wright, H. H., DeLong, G. R., et al. (2003) · Child Psychiatry and Human Development · doi:10.1023/a:1025321707947 · Cited by 299 · see citing works
Animal models of restricted repetitive behavior in autism.
Lewis, M., Tanimura, Y., Lee, L. W., & Bodfish, J. (2007) · Behavioural Brain Research · doi:10.1016/j.bbr.2006.08.023 · Cited by 270 · see citing works
Self-citationAssessing autism-like behavior in mice: Variations in social interactions among inbred strains
BOLIVAR, V, WALTERS, S., & PHOENIX, J. (2007) · Behavioural Brain Research · doi:10.1016/j.bbr.2006.09.007 · Cited by 264 · see citing works
Weeber, E. J., Jiang, Y., Elgersma, Y., Varga, A. W., Carrasquillo, Y., Brown, S. E., Christian, J. M., Mirnikjoo, B., Silva, A. J., Beaudet, A. L., et al. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-07-02634.2003 · Cited by 262 · see citing works
Ronald, A., Happé, F., & Plomin, R. (2005) · Developmental Science · doi:10.1111/j.1467-7687.2005.00433.x · Cited by 250 · see citing works
Mapping corpus callosum deficits in autism: An index of aberrant cortical connectivity
Vidal, C. N., Nicolson, R., DeVito, T. J., Hayashi, K. M., Geaga, J. A., Drost, D. J., Williamson, P. C., Rajakumar, N., Sui, Y., Dutton, R. A., et al. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.11.011 · Cited by 244 · see citing works
Episodic-like memory in mice: Simultaneous assessment of object, place and temporal order memory
Dere, E., Huston, J. P., & Silva, M. A. D. S. (2005) · Brain Research Protocols · doi:10.1016/j.brainresprot.2005.08.001 · Cited by 242 · see citing works
Griebel, G., Belzung, C., Misslin, R., & Vogel, E. (1993) · Behavioural Pharmacology · doi:10.1097/00008877-199312000-00009 · Cited by 239 · see citing works
Sankoorikal, G. M. V., Kaercher, K. A., Boon, C. J., Lee, J. K., & Brodkin, E. S. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.07.026 · Cited by 231 · see citing works
BALB/c mice: Low sociability and other phenotypes that may be relevant to autism
Brodkin, E. S. (2006) · Behavioural Brain Research · doi:10.1016/j.bbr.2006.06.025 · Cited by 223 · see citing works
Wahlsten, D., Metten, P., & Crabbe, J. C. (2003) · Brain Research · doi:10.1016/s0006-8993(03)02354-0 · Cited by 206 · see citing works
Pankevich, D. E., Baum, M. J., & Cherry, J. A. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.2376-04.2004 · Cited by 203 · see citing works
Duncan, G. E., Moy, S. S., Perez, A., Eddy, D. M., Zinzow-Kramer, W. M., Lieberman, J. A., Snouwaert, J. N., & Koller, B. H. (2004) · Behavioural Brain Research · doi:10.1016/j.bbr.2004.01.008 · Cited by 194 · see citing works
Self-citationWaiter, G. D., Williams, J. H. G., Murray, A. D., Gilchrist, A., Perrett, D. I., & Whiten, A. (2004) · NeuroImage · doi:10.1016/j.neuroimage.2004.08.049 · Cited by 188 · see citing works
Carlsson, M. L. (1998) · Journal of Neural Transmission · doi:10.1007/s007020050076 · Cited by 186 · see citing works
Saitoh, O. (2001) · Brain · doi:10.1093/brain/124.7.1317 · Cited by 175 · see citing works
Page, L., Daly, E., Schmitz, N., Simmons, A., Toal, F., Deeley, Q., Ambery, F., McAlonan, G. M., Murphy, K. C., & Murphy, D. G. M. (2006) · American Journal of Psychiatry · doi:10.1176/appi.ajp.163.12.2189 · Cited by 175 · see citing works
An MRI Study of the Corpus Callosum and Cerebellum in Mentally Retarded Autistic Individuals
Manes, F. F., Piven, J., Vrancic, D., Nanclares-Nogués, V., Plebst, C., & STARKSTEIN, S. E. (1999) · Journal of Neuropsychiatry · doi:10.1176/jnp.11.4.470 · Cited by 172 · see citing works
Social approach–avoidance behavior of inbred mouse strains towards DBA/2 mice
Brodkin, E. S., Hagemann, A., Nemetski, S. M., & Silver, L. M. (2004) · Brain Research · doi:10.1016/j.brainres.2003.12.013 · Cited by 170 · see citing works
Neotic preferences in laboratory rodents: Issues, assessment and substrates
Hughes, R. N. (2007) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2006.11.004 · Cited by 160 · see citing works
Less white matter concentration in autism: 2D voxel-based morphometry
Chung, M. K., Dalton, K. M., Alexander, A. L., & Davidson, R. J. (2004) · NeuroImage · doi:10.1016/j.neuroimage.2004.04.037 · Cited by 155 · see citing works
Novelty Seeking and Stereotypic Activation of Behavior in Mice with Disruption of the Dat1 Gene
Pogorelov, V. M., Rodriguiz, R. M., Insco, M. L., Caron, M. G., & Wetsel, W. C. (2005) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300724 · Cited by 151 · see citing works
Madani, R., Kozlov, S. V., Akhmedov, A. T., Cinelli, P., Kinter, J., Lipp, H., Sonderegger, P., & Wolfer, D. P. (2003) · Molecular and Cellular Neuroscience · doi:10.1016/s1044-7431(03)00077-0 · Cited by 140 · see citing works
A Rodent Model of Spontaneous Stereotypy
Powell, S. B., Newman, H. A., Pendergast, J., & Lewis, M. H. (1999) · Physiology & Behavior · doi:10.1016/s0031-9384(98)00303-5 · Cited by 139 · see citing works
Repetitive and stereotyped behaviours in pervasive developmental disorders
Carcani-Rathwell, I., Rabe‐Hesketh, S., & Santosh, P. (2005) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2005.01565.x · Cited by 133 · see citing works
Wersinger, S. R., Kelliher, K. R., Zufall, F., Lolait, S. J., O’Carroll, A., & Young, W. S. (2004) · Hormones and Behavior · doi:10.1016/j.yhbeh.2004.07.004 · Cited by 132 · see citing works
Enhanced initial and sustained intake of sucrose solution in mice with an oxytocin gene deletion
Amico, J. A., Vollmer, R. R., Cai, H.-M., Miedlar, J. A., & Rinaman, L. (2005) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00558.2005 · Cited by 120 · see citing works
Paulus, M. P., Dulawa, S. C., Ralph, R. J., & Geyer, M. A. (1999) · Brain Research · doi:10.1016/s0006-8993(99)01137-3 · Cited by 117 · see citing works
STOP knockout and NMDA NR1 hypomorphic mice exhibit deficits in sensorimotor gating
Fradley, R. L., O’Meara, G. F., Newman, R. J., Andrieux, A., Job, D., & Reynolds, D. S. (2005) · Behavioural Brain Research · doi:10.1016/j.bbr.2005.05.012 · Cited by 116 · see citing works
Belzung, C., & Berton, F. (1997) · Behavioural Pharmacology · doi:10.1097/00008877-199711000-00012 · Cited by 114 · see citing works
Ohl, F., Roedel, A., Binder, E., & Holsboer, F. (2003) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2003.02436.x · Cited by 110 · see citing works
Ralph, R. J., Paulus, M. P., & Geyer, M. A. (2001) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)29362-9 · Cited by 109 · see citing works
Selective blockade of spontaneous motor stereotypy via intrastriatal pharmacological manipulation
Presti, M. F., Mikes, H. M., & Lewis, M. H. (2003) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(02)01081-x · Cited by 94 · see citing works
Striatal opioid peptide content in an animal model of spontaneous stereotypic behavior
PRESTI, M., & Lewis, M. H. (2004) · Behavioural Brain Research · doi:10.1016/j.bbr.2004.08.003 · Cited by 83 · see citing works
DUNCAN, G., MOY, S., LIEBERMAN, J., & KOLLER, B. (2006) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2006.09.017 · Cited by 82 · see citing works
Self-citationNicot, A. B., Otto, T. A., Brabet, P., & DiCicco-Bloom, E. M. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.1910-04.2004 · Cited by 79 · see citing works
Duncan, G. E., Moy, S. S., Lieberman, J. A., & Koller, B. H. (2005) · Psychopharmacology · doi:10.1007/s00213-005-0214-1 · Cited by 78 · see citing works
Self-citationThe Effects of Isolation-Rearing on Preference by Rats for A Novel Environment
Hall, F. S., Humby, T., Wilkinson, L. S., & Robbins, T. W. (1997) · Physiology & Behavior · doi:10.1016/s0031-9384(97)00117-0 · Cited by 66 · see citing works
Amphetamine-induced disruption of prepulse inhibition in mice with reduced NMDA receptor function.
Moy, S., Perez, A., Koller, B., & Duncan, G. (2006) · Brain Research · doi:10.1016/j.brainres.2006.03.073 · Cited by 65 · see citing works
Self-citationSpontaneous Stereotypy in an Animal Model of Down Syndrome: Ts65Dn Mice
Turner, C. A., Presti, M. F., Newman, H. A., Bugenhagen, P., Crnic, L. S., & Lewis, M. H. (2001) · Behavior Genetics · doi:10.1023/a:1012226603255 · Cited by 62 · see citing works
Pharmacological and genetic influences on hole-board behaviors in mice
Kliethermes, C. L., & Crabbe, J. C. (2006) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2006.07.007 · Cited by 59 · see citing works
Nilsson, M., Waters, N., Waters, N., Carlsson, A., & Carlsson, M. L. (2001) · Journal of Neural Transmission · doi:10.1007/s007020170008 · Cited by 59 · see citing works
Effects of acute alcohol administration on object recognition learning in C57BL/6J mice
Ryabinin, A. E., Miller, M. N., & Durrant, S. (2002) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(01)00661-x · Cited by 59 · see citing works
Altered cortico‐striatal synaptic plasticity and related behavioural impairments in reeler mice
Marrone, M. C., Marinelli, S., Biamonte, F., Keller, F., Sgobio, C., Ammassari‐Teule, M., Bernardi, G., & Mercuri, N. B. (2006) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2006.05083.x · Cited by 58 · see citing works
Genetic independence of mouse measures of some aspects of novelty seeking
Kliethermes, C. L., & Crabbe, J. C. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0509724103 · Cited by 57 · see citing works
Depino, A. M., & Gross, C. T. (2007) · Behavioural Brain Research · doi:10.1016/j.bbr.2006.11.025 · Cited by 57 · see citing works
Mooney, E. L., Gray, K. M., & Tonge, B. J. (2006) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-006-0499-6 · Cited by 57 · see citing works
Neophobia, sensory and cognitive functions, and hedonic responses in vitamin D receptor mutant mice
Minasyan, A., Keisala, T., Lou, Y., Kalueff, A. V., & Tuohimaa, P. (2007) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2007.03.032 · Cited by 53 · see citing works
Drew, C. J. G., Kyd, R. J., & Morton, A. J. (2007) · Human Molecular Genetics · doi:10.1093/hmg/ddm181 · Cited by 51 · see citing works
Effects of Melatonin on Neophobic Responses in Different Strains of Mice
Kopp, C., Vogel, E., Rettori, M., Delagrange, P., Lemaître, B. J., & Misslin, R. (1999) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(99)00023-4 · Cited by 43 · see citing works
An automated method for studying exploratory and stereotyped behaviour in rats
Makanjuola, R. O. A., Hill, G., Maben, I., Dow, R. C., & Ashcroft, G. W. (1977) · Psychopharmacology · doi:10.1007/bf00426711 · Cited by 42 · see citing works
Makanjuola, R. O. A., Hill, G. E., Dow, R. C., Campbell, G., & Ashcroft, G. P. (1977) · Psychopharmacology · doi:10.1007/bf00432819 · Cited by 41 · see citing works
Presti, M. L. (2002) · Physiology & Behavior · doi:10.1016/s0031-9384(02)00641-8 · Cited by 22 · see citing works
Affiliation and neophobia in developing mice prenatally exposed to oxazepam
Terranova, M. L., Alleva, E., & Laviola, G. (1994) · Behavioural Pharmacology · doi:10.1097/00008877-199402000-00006 · Cited by 18 · see citing works
Pascual, J., & Heinrichs, S. C. (2007) · Epilepsia · doi:10.1111/j.1528-1167.2007.01024.x · Cited by 15 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Behavioural phenotyping assays for mouse models of autism
Silverman, J. L., Yang, M., Lord, C., & Crawley, J. N. (2010) · Nature Reviews Neuroscience · doi:10.1038/nrn2851 · Cited by 1,462 · see citing works
Self-citationAutomated Three‐Chambered Social Approach Task for Mice
Yang, M., Silverman, J. L., & Crawley, J. N. (2011) · Current Protocols in Neuroscience · doi:10.1002/0471142301.ns0826s56 · Cited by 598 · see citing works
Self-citationUnusual repertoire of vocalizations in the BTBR T+tf/J mouse model of autism
Scattoni, M. L., Gandhy, S. U., Ricceri, L., & Crawley, J. N. (2008) · PLoS ONE · doi:10.1371/journal.pone.0003067 · Cited by 550 · see citing works
Self-citationMicroRNA-219 modulates NMDA receptor-mediated neurobehavioral dysfunction
Kocerha, J., Faghihi, M. A., López-Toledano, M. A., Huang, J., Ramsey, A. J., Caron, M. G., Salès, N., Willoughby, D., Elmén, J., Hansen, H. F., et al. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0805854106 · Cited by 292 · see citing works
Current Enlightenment About Etiology and Pharmacological Treatment of Autism Spectrum Disorder
Eissa, N., Al‐Houqani, M., Sadeq, A. S., Ojha, S. K., Sasse, A., & Sadek, B. S. (2018) · Frontiers in Neuroscience · doi:10.3389/fnins.2018.00304 · Cited by 263 · see citing works
Silverman, J. L., Smith, D. G., Rizzo, S. J. S., Karras, M. N., Turner, S. M., Tolu, S. S., Bryce, D. K., Smith, D. L., Fonseca, K., Ring, R. H., et al. (2012) · Science Translational Medicine · doi:10.1126/scitranslmed.3003501 · Cited by 251 · see citing works
Self-citationThe pathophysiology of restricted repetitive behavior
Lewis, M. H., & Kim, S. (2009) · Journal of Neurodevelopmental Disorders · doi:10.1007/s11689-009-9019-6 · Cited by 233 · see citing works
Han, S., Tai, C., Jones, C. J., Scheuer, T., & Catterall, W. A. (2014) · Neuron · doi:10.1016/j.neuron.2014.01.016 · Cited by 231 · see citing works
Sarachana, T., Zhou, R., Chen, G., Manji, H. K., & Hu, V. W. (2010) · Genome Medicine · doi:10.1186/gm144 · Cited by 229 · see citing works
Spencer, C. M., Alekseyenko, O. V., Hamilton, S. M., Thomas, A. M., Serysheva, E., Yuva‐Paylor, L. A., & Paylor, R. E. (2011) · Autism Research · doi:10.1002/aur.168 · Cited by 215 · see citing works
Mehta, M. V., Gandal, M. J., & Siegel, S. J. (2011) · PLoS ONE · doi:10.1371/journal.pone.0026077 · Cited by 182 · see citing works
Wöhr, M., & Scattoni, M. L. (2013) · Behavioural Brain Research · doi:10.1016/j.bbr.2013.05.047 · Cited by 178 · see citing works
To Approach or Avoid: An Introductory Overview of the Study of Anxiety Using Rodent Assays
La-Vu, M. Q., Tobias, B. C., Schuette, P. J., & Adhikari, A. (2020) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2020.00145 · Cited by 184 · see citing works
Stephenson, D. T., O'Neill, S. M., Narayan, S., Tiwari, A., Arnold, E., Samaroo, H. D., Du, F., Ring, R. H., Campbell, B., Pletcher, M., et al. (2011) · Molecular Autism · doi:10.1186/2040-2392-2-7 · Cited by 180 · see citing works
Behavioral phenotypes of genetic mouse models of autism
Kazdoba, T. M., Leach, P. T., & Crawley, J. N. (2015) · Genes Brain & Behavior · doi:10.1111/gbb.12256 · Cited by 179 · see citing works
Self-citationWhat Can We Learn about Autism from Studying Fragile X Syndrome?
Budimirovic, D. B., & Kaufmann, W. E. (2011) · Developmental Neuroscience · doi:10.1159/000330213 · Cited by 176 · see citing works
Bauman, M. D., Iosif, A.-M., Ashwood, P., Braunschweig, D., Lee, A., Schumann, C. M., Van de Water, J., & Amaral, D. G. (2013) · Translational Psychiatry · doi:10.1038/tp.2013.47 · Cited by 174 · see citing works
Mao, P., Mańczak, M., Calkins, M. J., Truong, Q., Reddy, T. P., Reddy, A. P., Shirendeb, U. P., Lo, H., Rabinovitch, P. S., & Reddy, P. H. (2012) · Human Molecular Genetics · doi:10.1093/hmg/dds128 · Cited by 174 · see citing works
Translational Mouse Models of Autism: Advancing Toward Pharmacological Therapeutics
Kazdoba, T. M., Leach, P. T., Yang, M., Silverman, J. L., Solomon, M., & Crawley, J. N. (2015) · Current topics in behavioral neurosciences · doi:10.1007/7854_2015_5003 · Cited by 172 · see citing works
Self-citationMotor and cognitive stereotypies in the BTBR T+tf/J mouse model of autism
Pearson, B. L., Pobbe, R. L. H., Defensor, E. B., Oasay, L., Bolivar, V. J., Blanchard, D. C., & Blanchard, R. J. (2011) · Genes, Brain and Behavior · doi:10.1111/j.1601-183x.2010.00659.x · Cited by 171 · see citing works
Reduced scent marking and ultrasonic vocalizations in the BTBR T+tf/J mouse model of autism
Wöhr, M., Roullet, F. I., & Crawley, J. N. (2011) · Genes, Brain and Behavior · doi:10.1111/j.1601-183x.2010.00582.x · Cited by 169 · see citing works
Self-citationIntegrins in synapse regulation
Park, Y. K., & Goda, Y. (2016) · Nature Reviews Neuroscience · doi:10.1038/nrn.2016.138 · Cited by 167 · see citing works
Assessment of NMDA receptor NR1 subunit hypofunction in mice as a model for schizophrenia
Halene, T. B., Ehrlichman, R. S., Liang, Y., Christian, E. P., Jonak, G. J., Gur, T., Blendy, J. A., Dow, H. C., Brodkin, E. S., Schneider, F. W., et al. (2009) · Genes Brain & Behavior · doi:10.1111/j.1601-183x.2009.00504.x · Cited by 162 · see citing works
The BTBR T+tf/J mouse model for autism spectrum disorders–in search of biomarkers
Meyza, K. Z., Defensor, E. B., Jensen, A. L., Corley, M. J., Pearson, B. L., Pobbe, R. L. H., Bolivar, V. J., Blanchard, D. C., & Blanchard, R. J. (2013) · Behavioural Brain Research · doi:10.1016/j.bbr.2012.07.021 · Cited by 147 · see citing works
Low stress reactivity and neuroendocrine factors in the BTBR T+tf/J mouse model of autism
Silverman, J. L., Yang, M., Turner, S. M., Katz, A. M., Bell, D. B., Koenig, J. I., & Crawley, J. N. (2010) · Neuroscience · doi:10.1016/j.neuroscience.2010.09.059 · Cited by 146 · see citing works
Self-citationEllegood, J., Babineau, B. A., Henkelman, R. M., Lerch, J. P., & Crawley, J. N. (2013) · NeuroImage · doi:10.1016/j.neuroimage.2012.12.029 · Cited by 135 · see citing works
Self-citationMcTighe, S. M., Webb, S. J. N., Lin, Q., Hughes, Z. A., & Smith, D. G. (2013) · PLoS ONE · doi:10.1371/journal.pone.0062189 · Cited by 133 · see citing works
Environmental enrichment as a therapy for autism: A clinical trial replication and extension.
Woo, C. C., Donnelly, J. H., Steinberg-Epstein, R., & Leon, M. (2015) · Behavioral Neuroscience · doi:10.1037/bne0000068 · Cited by 128 · see citing works
Dodero, L., Damiano, M., Galbusera, A., Bifone, A., Tsaftsaris, S. A., Scattoni, M. L., & Gozzi, A. (2013) · PLoS ONE · doi:10.1371/journal.pone.0076655 · Cited by 116 · see citing works
Core features of frontotemporal dementia recapitulated in progranulin knockout mice
Ghoshal, N., Dearborn, J. T., Wozniak, D. F., & Cairns, N. J. (2012) · Neurobiology of Disease · doi:10.1016/j.nbd.2011.08.029 · Cited by 127 · see citing works
Kirsten, T. B., Chaves‐Kirsten, G. P., Chaible, L. M., Silva, A. C., Martins, D. O., Britto, L. R. G., Dagli, M. L. Z., Torrão, A. S., Palermo‐Neto, J., & Bernardi, M. M. (2012) · Journal of Neuroscience Research · doi:10.1002/jnr.23089 · Cited by 122 · see citing works
Pobbe, R. L. H., Pearson, B. L., Defensor, E. B., Bolivar, V. J., Blanchard, D. C., & Blanchard, R. J. (2010) · Behavioural Brain Research · doi:10.1016/j.bbr.2010.06.025 · Cited by 121 · see citing works
Mice with reduced NMDA receptor expression: more consistent with autism than schizophrenia?
Gandal, M. J., Anderson, R. L., Billingslea, E. N., Carlson, G. C., Roberts, T. P. L., & Siegel, S. J. (2012) · Genes Brain & Behavior · doi:10.1111/j.1601-183x.2012.00816.x · Cited by 120 · see citing works
Low sociability in BTBR T+tf/J mice is independent of partner strain
Yang, M., Abrams, D. N., Zhang, J. Y., Weber, M. D., Katz, A. M., Clarke, A. M., Silverman, J. L., & Crawley, J. N. (2012) · Physiology & Behavior · doi:10.1016/j.physbeh.2011.12.025 · Cited by 112 · see citing works
Self-citationCarter, M. D., Shah, C. R., Muller, C. L., Crawley, J. N., Carneiro, A. M. D., & Veenstra-VanderWeele, J. M. (2011) · Autism Research · doi:10.1002/aur.180 · Cited by 112 · see citing works
Self-citationHa, S., Lee, D., Cho, Y. S., Chung, C., Yoo, Y.-E., Kim, J., Lee, J., Kim, W., Kim, H., Bae, Y. C., et al. (2016) · Journal of Neuroscience · doi:10.1523/jneurosci.1849-16.2016 · Cited by 107 · see citing works
Glutamate receptor dysfunction and drug targets across models of autism spectrum disorders
Carlson, G. C. (2012) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2011.02.003 · Cited by 102 · see citing works
Neural Mechanisms Underlying Repetitive Behaviors in Rodent Models of Autism Spectrum Disorders
Gandhi, T., & Lee, C. C. (2021) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2020.592710 · Cited by 94 · see citing works
Autism Spectrum Disorders: Translating human deficits into mouse behavior
Pasciuto, E., Borrie, S. C., Kanellopoulos, A. K., Santos, A. R. S., Cappuyns, E., D’Andrea, L., Pacini, L., & Bagni, C. (2015) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2015.07.013 · Cited by 92 · see citing works
Barnes, S. A., Pinto-Duarte, A., Kappe, A., Zembrzycki, A., Metzler, A., Mukamel, E. A., Lucero, J., Wang, X., Sejnowski, T. J., Markou, A., et al. (2015) · Molecular Psychiatry · doi:10.1038/mp.2015.113 · Cited by 92 · see citing works
Ohba, C., Shiina, M., Tohyama, J., Haginoya, K., Lerman‐Sagie, T., Okamoto, N., Blumkin, L., Lev, D., Mukaida, S., Nozaki, F., et al. (2015) · Epilepsia · doi:10.1111/epi.12987 · Cited by 92 · see citing works
Segal‐Gavish, H., Karvat, G., Barak, N., Barzilay, R., Ganz, J., Edry, L., Aharony, I., Offen, D., & Kimchi, T. (2015) · Autism Research · doi:10.1002/aur.1530 · Cited by 93 · see citing works
Deliu, E., Arecco, N., Morandell, J., Dotter, C. P., Contreras, X., Girardot, C., Käsper, E.-L., Kozlova, A., Kishi, K., Chiaradia, I., et al. (2018) · Nature Neuroscience · doi:10.1038/s41593-018-0266-2 · Cited by 89 · see citing works
Dougherty, J. D., Maloney, S. E., Wozniak, D. F., Rieger, M. A., Sonnenblick, L. I., Coppola, G., Mahieu, N. G., Zhang, J., Cai, J., Patti, G. J., et al. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.4762-12.2013 · Cited by 86 · see citing works
Autism spectrum and obsessive–compulsive disorders: OC behaviors, phenotypes and genetics
Jacob, S., Landeros‐Weisenberger, A., & Leckman, J. F. (2009) · Autism Research · doi:10.1002/aur.108 · Cited by 91 · see citing works
Eltokhi, A., Kurpiers, B., & Pitzer, C. (2020) · Scientific Reports · doi:10.1038/s41598-020-67758-0 · Cited by 86 · see citing works
Lai, J., Sobala-Drozdowski, M., Zhou, L., Doering, L. C., Faure, P. A., & Foster, J. A. (2013) · Behavioural Brain Research · doi:10.1016/j.bbr.2013.10.049 · Cited by 84 · see citing works
Homberg, J. R., Kyzar, E. J., Nguyen, M., Norton, W., Pittman, J. T., Poudel, M. K., Gaikwad, S., Nakamura, S., Koshiba, M., Yamanouchi, H., et al. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.03.013 · Cited by 83 · see citing works
Early-life seizures result in deficits in social behavior and learning
Lugo, J. N., Swann, J. W., & Anderson, A. E. (2014) · Experimental Neurology · doi:10.1016/j.expneurol.2014.03.014 · Cited by 75 · see citing works
Dysfunctional dopaminergic neurotransmission in asocial BTBR mice
Squillace, M., Dodero, L., Federici, M., Migliarini, S., Errico, F., Napolitano, F., Krashia, P., Maio, A. D., Galbusera, A., Bifone, A., et al. (2014) · Translational Psychiatry · doi:10.1038/tp.2014.69 · Cited by 73 · see citing works
Yennawar, M., White, R. S., & Jensen, F. E. (2019) · Journal of Neuroscience · doi:10.1523/jneurosci.2041-18.2019 · Cited by 71 · see citing works
Langley, E. A., Krykbaeva, M., Blusztajn, J. K., & Mellott, T. J. (2014) · Behavioural Brain Research · doi:10.1016/j.bbr.2014.09.043 · Cited by 70 · see citing works
Repetitive behavior profile and supersensitivity to amphetamine in the C58/J mouse model of autism
Moy, S. S., Riddick, N. V., Nikolova, V. D., Teng, B. L., Agster, K. L., Nonneman, R. J., Young, N. B., Baker, L. K., Nadler, J. J., & Bodfish, J. W. (2013) · Behavioural Brain Research · doi:10.1016/j.bbr.2013.10.052 · Cited by 68 · see citing works
Self-citationEffects of Environmental Enrichment on Repetitive Behaviors in the BTBR T+tf/J Mouse Model of Autism
Reynolds, S., Urruela, M., & Devine, D. P. (2013) · Autism Research · doi:10.1002/aur.1298 · Cited by 65 · see citing works
Daimon, C. M., Jasien, J., Wood, W. H., Zhang, Y., Becker, K. G., Silverman, J. L., Crawley, J. N., Martin, B., & Maudsley, S. R. (2015) · Frontiers in Physiology · doi:10.3389/fphys.2015.00324 · Cited by 67 · see citing works
Self-citationEnvironmental Enrichment Therapy for Autism: Outcomes with Increased Access
Aronoff, E., Hillyer, R., & Leon, M. (2016) · Neural Plasticity · doi:10.1155/2016/2734915 · Cited by 64 · see citing works
Kirsten, T. B., Chaves-Kirsten, G. P., Bernardes, S., Scavone, C., Sarkis, J. E., Bernardi, M. M., & Felicio, L. F. (2015) · PLOS ONE · doi:10.1371/journal.pone.0134565 · Cited by 65 · see citing works
Mouse Models of Autism: Testing Hypotheses About Molecular Mechanisms
Roullet, F., & Crawley, J. N. (2011) · Current topics in behavioral neurosciences · doi:10.1007/7854_2010_113 · Cited by 65 · see citing works
Self-citationMonogenic mouse models of social dysfunction: Implications for autism
Oddi, D., Crusio, W. E., D'Amato, F. R., & Pietropaolo, S. (2013) · Behavioural Brain Research · doi:10.1016/j.bbr.2013.01.002 · Cited by 62 · see citing works
The Roles of Oxytocin and CD38 in Social or Parental Behaviors
Lopatina, O. L., Ивановна, И. А., Salmina, A. B., & Higashida, H. (2013) · Frontiers in Neuroscience · doi:10.3389/fnins.2012.00182 · Cited by 64 · see citing works
Marcinkiewcz, C. A., Dorrier, C., López, A. J., & Kash, T. L. (2014) · Neuropharmacology · doi:10.1016/j.neuropharm.2014.09.003 · Cited by 62 · see citing works
Reversal of social deficits by subchronic oxytocin in two autism mouse models
Teng, B. L., Nikolova, V. D., Riddick, N. V., Agster, K. L., Crowley, J. J., Baker, L. K., Koller, B. H., Pedersen, C. A., Jarstfer, M. B., & Moy, S. S. (2016) · Neuropharmacology · doi:10.1016/j.neuropharm.2015.12.025 · Cited by 62 · see citing works
Self-citationEnriched rearing improves behavioral responses of an animal model for CNV-based autistic-like traits
Lacaria, M., Spencer, C. M., Gu, W., Paylor, R. E., & Lupski, J. R. (2012) · Human Molecular Genetics · doi:10.1093/hmg/dds124 · Cited by 59 · see citing works
Meeking, M. M., MacFabe, D. F., Mepham, J. R., Foley, K. A., Tichenoff, L. J., Boon, F. H., Kavaliers, M., & Ossenkopp, K. (2019) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2019.109794 · Cited by 58 · see citing works
Kohl, C., Riccio, O., Grosse, J., Zanoletti, O., Fournier, C., Schmidt, M. V., & Sandi, C. (2013) · PLoS ONE · doi:10.1371/journal.pone.0056871 · Cited by 57 · see citing works
Disruption of social approach by MK-801, amphetamine, and fluoxetine in adolescent C57BL/6J mice
Moy, S. S., Nonneman, R. J., Shafer, G. O., Nikolova, V. D., Riddick, N. V., Agster, K. L., Baker, L. K., & Knapp, D. J. (2012) · Neurotoxicology and Teratology · doi:10.1016/j.ntt.2012.07.007 · Cited by 56 · see citing works
Self-citation5HT2A receptor blockade in dorsomedial striatum reduces repetitive behaviors in BTBR mice
Amodeo, D. A., Rivera, E., Cook, E. H., Sweeney, J. A., & Ragozzino, M. E. (2016) · Genes Brain & Behavior · doi:10.1111/gbb.12343 · Cited by 55 · see citing works
BTBR T+tf/J mice: Autism-relevant behaviors and reduced fractone-associated heparan sulfate
Blanchard, D. C., Defensor, E. B., Meyza, K. Z., Pobbe, R. L. H., Pearson, B. L., Bolivar, V. J., & Blanchard, R. J. (2011) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2011.06.008 · Cited by 54 · see citing works
Lee, S., Lee, E., Kim, R., Kim, J., Lee, S., Park, H., Yang, E., Kim, H., & Kim, E. (2018) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2018.00209 · Cited by 53 · see citing works
Antipsychotic-like activity of Noni (Morinda citrifolia Linn.) in mice
Pandy, V., Narasingam, M., & Mohamed, Z. (2012) · BMC Complementary and Alternative Medicine · doi:10.1186/1472-6882-12-186 · Cited by 53 · see citing works
Muehlmann, A., Edington, G., Mihalik, A., Buchwald, Z., Koppuzha, D., Korah, M., & Lewis, M. (2012) · Behavioural Brain Research · doi:10.1016/j.bbr.2012.07.041 · Cited by 46 · see citing works
Corticosteroid and neurosteroid dysregulation in an animal model of autism, BTBR mice
Frye, C. A., & Llaneza, D. C. (2010) · Physiology & Behavior · doi:10.1016/j.physbeh.2010.03.005 · Cited by 52 · see citing works
Studying Autism in Rodent Models: Reconciling Endophenotypes with Comorbidities
Argyropoulos, A., Gilby, K. L., & Hill‐Yardin, E. L. (2013) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2013.00417 · Cited by 51 · see citing works
Kaur, P., Armugam, A., & Jeyaseelan, K. (2012) · Journal of Toxicology · doi:10.1155/2012/870150 · Cited by 48 · see citing works
Gusmão, I. D., Monteiro, B. M. M., Cornélio, G. O. S., Fonseca, C. S., Moraes, M. F. D., & Pereira, G. S. (2011) · Behavioural Brain Research · doi:10.1016/j.bbr.2011.12.040 · Cited by 47 · see citing works
Systematic autistic-like behavioral phenotyping of 4 mouse strains using a novel wheel-running assay
Karvat, G., & Kimchi, T. (2012) · Behavioural Brain Research · doi:10.1016/j.bbr.2012.05.028 · Cited by 45 · see citing works
Faraji, J., Karimi, M., Lawrence, C., Mohajerani, M. H., & Metz, G. A. S. (2018) · Translational Psychiatry · doi:10.1038/s41398-018-0280-x · Cited by 46 · see citing works
Lieberman, O. J., Cartocci, V., Pigulevskiy, I., Molinari, M., Carbonell, J., Broseta, M. B., Post, M. R., Sulzer, D., Borgkvist, A., & Santini, E. (2020) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2020.00070 · Cited by 47 · see citing works
Oxotremorine treatment reduces repetitive behaviors in BTBR T+ tf/J mice
Amodeo, D. A., Yi, J., Sweeney, J. A., & Ragozzino, M. E. (2014) · Frontiers in Synaptic Neuroscience · doi:10.3389/fnsyn.2014.00017 · Cited by 44 · see citing works
Wöhr, M. (2015) · Frontiers in Neuroscience · doi:10.3389/fnins.2015.00073 · Cited by 43 · see citing works
Puścian, A., ÅÄTMski, S., Górkiewicz, T., Meyza, K. Z., Lipp, H., & Knapska, E. (2014) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2014.00140 · Cited by 43 · see citing works
Veenstra-VanderWeele, J. M., Jessen, T. N., Thompson, B. J., Carter, M. D., Prasad, H. C., Steiner, J. A., Sutcliffe, J. S., & Blakely, R. (2009) · Journal of Neurodevelopmental Disorders · doi:10.1007/s11689-009-9020-0 · Cited by 42 · see citing works
Amodeo, D. A., Pahua, A. E., Zarate, M., Taylor, J. A., Peterson, S., Posadas, R., Oliver, B. L., & Amodeo, L. R. (2019) · Behavioural Brain Research · doi:10.1016/j.bbr.2019.112028 · Cited by 43 · see citing works
The autism diagnosis in translation: shared affect in children and mouse models of ASD
Bishop, S. L., & Lahvis, G. P. (2011) · Autism Research · doi:10.1002/aur.216 · Cited by 40 · see citing works
Pobbe, R. L. H., Pearson, B. L., Blanchard, D. C., & Blanchard, R. J. (2012) · Physiology & Behavior · doi:10.1016/j.physbeh.2012.02.024 · Cited by 40 · see citing works
A systematic-review of olfactory deficits in neurodevelopmental disorders: From mouse to human
Lyons-Warren, A. M., Herman, I., Hunt, P. J., & Arenkiel, B. R. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.02.024 · Cited by 37 · see citing works
Burket, J. A., Cannon, W. R., Jacome, L. F., & Deutsch, S. I. (2010) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2010.08.014 · Cited by 35 · see citing works
Meyza, K. Z., Blanchard, D. C., Pearson, B. L., Pobbe, R. L. H., & Blanchard, R. J. (2011) · Behavioural Brain Research · doi:10.1016/j.bbr.2011.11.004 · Cited by 35 · see citing works
Khongrum, J., & Wattanathorn, J. (2015) · Journal of Acupuncture and Meridian Studies · doi:10.1016/j.jams.2015.06.008 · Cited by 34 · see citing works
Ahadullah, Yau, S., Lu, H., Lee, T. M. C., Guo, H., & Chan, C. C. H. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.06.043 · Cited by 33 · see citing works
GluN1 hypomorph mice exhibit wide‐ranging behavioral alterations
Barkus, C., Dawson, L. A., Sharp, T., & Bannerman, D. M. (2012) · Genes Brain & Behavior · doi:10.1111/j.1601-183x.2012.00767.x · Cited by 31 · see citing works
Abnormal repetitive behaviors in zebrafish and their relevance to human brain disorders
Zabegalov, K. N., Khatsko, S. L., Lakstygal, A. M., Demin, K. A., Cleal, M., Fontana, B. D., McBride, S. D., Harvey, B. H., de Abreu, M. S., Parker, M. O., et al. (2019) · Behavioural Brain Research · doi:10.1016/j.bbr.2019.03.044 · Cited by 31 · see citing works
Magno, L., Asgarian, Z., Pendolino, V., Velona, T., Mackintosh, A. I., Lee, F., Stryjewska, A., Zimmer, C., Guillemot, F., Farrant, M., et al. (2021) · Cell Reports · doi:10.1016/j.celrep.2021.109249 · Cited by 28 · see citing works
Low home cage social behaviors in BTBR T+tf/J mice during juvenile development
Babineau, B. A., Yang, M., Berman, R. F., & Crawley, J. N. (2013) · Physiology & Behavior · doi:10.1016/j.physbeh.2013.03.006 · Cited by 30 · see citing works
Self-citationAhmadi, B. B. M., Afarinesh, M. R., Jafaripour, L., & Sheibani, V. (2022) · Brain and Behavior · doi:10.1002/brb3.2993 · Cited by 29 · see citing works
Visual capabilities and cortical maps in BALB/c mice
Yeritsyan, N., Lehmann, K., Puk, O., Graw, J., & Löwel, S. (2012) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2012.08195.x · Cited by 27 · see citing works
Preweaning Sensorimotor Deficits and Adolescent Hypersociability in Grin1 Knockdown Mice
Moy, S. S., Nikolova, V. D., Riddick, N. V., Baker, L. K., & Koller, B. H. (2012) · Developmental Neuroscience · doi:10.1159/000337984 · Cited by 27 · see citing works
Self-citationMotivational Disturbances and Effects of L-dopa Administration in Neurofibromatosis-1 Model Mice
Wozniak, D. F., Diggs‐Andrews, K. A., Conyers, S. B., Yuede, C. M., Dearborn, J. T., Brown, J. A., Tokuda, K., Izumi, Y., Zorumski, C. F., & Gutmann, D. H. (2013) · PLoS ONE · doi:10.1371/journal.pone.0066024 · Cited by 27 · see citing works
Kitanaka, J., Kitanaka, N., Tatsuta, T., Hall, F. S., Uhl, G. R., Tanaka, K., Nishiyama, N., Morita, Y., & Takemura, M. (2008) · Psychopharmacology · doi:10.1007/s00213-008-1425-z · Cited by 27 · see citing works
Saadat, M., Taherian, A. A., Aldaghi, M. R., Raise‐Abdullahi, P., Sameni, H. R., & Vafaei, A. A. (2023) · Brain and Behavior · doi:10.1002/brb3.3224 · Cited by 26 · see citing works
- Authors
- Moy, S. S., Nadler, J. J., Poe, M. D., Nonneman, R. J., Young, N. B., Koller, B. H., Crawley, J. N., Duncan, G. E., & Bodfish, J. W.
- Affiliations
- University of North Carolina at Chapel Hill (US)
- Corresponding author
- Moy, Sheryl S.
- Venue
- Behavioural Brain Research
- Publisher
- Elsevier BV
- Published
- 2008-03
- Volume
- 188
- Issue
- 1
- Pages
- 178-194
- ISSN
- 0166-4328 (ISSN-L)
- PMC
- PMC2349090
- OpenAlex
- W2050597016
- Cited by
- 195
- References
- 84
- Citations by year
- 2026: 6 · 2025: 3 · 2024: 4 · 2023: 7 · 2022: 10 · 2021: 11 · 2020: 9 · 2019: 10 · 2018: 13 · 2017: 5 · 2016: 9 · 2015: 14 · 2014: 11 · 2013: 21 · 2012: 26
- FWCI
- 6.12
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Behavioural Brain Research (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Carolina Digital Repository (University of North Carolina at Chapel Hill) (submittedVersion)
- UNC Libraries
- Funders
- National Institutes of Health (5u54mh066418-05)
- National Institute of Mental Health (U54-MH066418, U54 MH 66418, R01MH063398, R21MH085254, R01MH073402, MH063398)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (P30HD003110)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetics and Neurodevelopmental Disorders
- Social Sciences › Psychology › Social Psychology › Neuroendocrine regulation and behavior
- Keywords
- repetitive behavior, autism spectrum disorder, inbred mouse strains, BTBR T+tf/J mice, NMDA receptor hypofunction, GRIN1, resistance to change, restricted interests, self-harm, stereotypy, mouse models of autism
- MeSH terms
- Animals, Autistic Disorder, Behavior, Animal, Carrier Proteins, Discrimination Learning, Disease Models, Animal, Exploratory Behavior, Food Preferences, Male, Mice, Inbred BALB C, Mice, Inbred C57BL, Mice, Inbred Strains, Mice, Neurologic Mutants, Nerve Tissue Proteins, Set, Psychology, Smell, Social Behavior, Species Specificity, Receptors, N-Methyl-D-Aspartate, Self-Injurious Behavior, Mice
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review