Neuroanatomical analysis of the BTBR mouse model of autism using magnetic resonance imaging and diffusion tensor imaging

Diagnostic and Statistical Manual of Mental Disorders

Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,841 · see citing works

Diagnostic and Statistical Manual of Mental Disorders.

Widiger, T. A. (2000) · Oxford University Press eBooks · doi:10.1037/10518-009 · Cited by 19,767 · see citing works

Thresholding of statistical maps in functional neuroimaging using the false discovery rate

Genovese, C. R., Lazar, N. A., & Nichols, T. (2002) · NeuroImage · doi:10.1006/nimg.2001.1037 · Cited by 4,923 · see citing works

The basis of anisotropic water diffusion in the nervous system—A technical review.

Beaulieu, C. (2002) · NMR in Biomedicine · doi:10.1002/nbm.782 · Cited by 4,653 · see citing works

Automatic 3D intersubject registration of MR volumetric data in standardized Talairach space

Collins, D. L., Neelin, P., Peters, T. M., & Evans, A. C. (1994) · Journal of Computer Assisted Tomography · doi:10.1097/00004728-199403000-00005 · Cited by 3,431 · cited 2× · see citing works

The Social Brain: Neural Basis of Social Knowledge

Adolphs, R. (2009) · Annual Review of Psychology · doi:10.1146/annurev.psych.60.110707.163514 · Cited by 1,827 · see citing works

Neuroanatomy of autism

Amaral, D. G., Schumann, C. M., & Nordahl, C. W. (2008) · Trends in Neurosciences · doi:10.1016/j.tins.2007.12.005 · Cited by 1,492 · see citing works

Behavioural phenotyping assays for mouse models of autism

Silverman, J. L., Yang, M., Lord, C., & Crawley, J. N. (2010) · Nature Reviews Neuroscience · doi:10.1038/nrn2851 · Cited by 1,462 · see citing works

Autism and Abnormal Development of Brain Connectivity: Figure 1.

Belmonte, M. K., Allen, G., Beckel-Mitchener, A., Boulanger, L. M., Carper, R. A., & Webb, S. J. (2004) · The Journal of Neuroscience · doi:10.1523/jneurosci.3340-04.2004 · Cited by 1,217 · see citing works

Agenesis of the corpus callosum: Genetic, developmental and functional aspects of connectivity

Paul, L. K., Brown, W. S., Adolphs, R., Tyszka, J. M., Richards, L. J., Mukherjee, P., & Sherr, E. H. (2007) · Nature Reviews Neuroscience · doi:10.1038/nrn2107 · Cited by 830 · see citing works

Autism‐like behavioral phenotypes in BTBR T+tf/J mice

McFarlane, H. G., Kusek, G. K., Yang, M., Phoenix, J. L., Bolivar, V. J., & Crawley, J. N. (2008) · Genes, Brain and Behavior · doi:10.1111/j.1601-183x.2007.00330.x · Cited by 812 · see citing works

Mouse behavioral tasks relevant to autism: Phenotypes of 10 inbred strains

MOY, S., NADLER, J., YOUNG, N., PEREZ, A., HOLLOWAY, L., BARBARO, R., BARBARO, J., WILSON, L., THREADGILL, D., & LAUDER, J. (2007) · Behavioural Brain Research · doi:10.1016/j.bbr.2006.07.030 · Cited by 776 · see citing works

The optimal template effect in hippocampus studies of diseased populations

Avants, B. B., Yushkevich, P., Pluta, J., Minkoff, D., Korczykowski, M., Detre, J., & Gee, J. C. (2010) · NeuroImage · doi:10.1016/j.neuroimage.2009.09.062 · Cited by 640 · see citing works

Automated Three‐Chambered Social Approach Task for Mice

Yang, M., Silverman, J. L., & Crawley, J. N. (2011) · Current Protocols in Neuroscience · doi:10.1002/0471142301.ns0826s56 · Cited by 598 · see citing works

Simple Behavioral Assessment of Mouse Olfaction

Yang, M., & Crawley, J. N. (2009) · Current Protocols in Neuroscience · doi:10.1002/0471142301.ns0824s48 · Cited by 573 · see citing works

HOW THE BRAIN PROCESSES SOCIAL INFORMATION: Searching for the Social Brain

Insel, T. R., & Fernald, R. D. (2004) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.27.070203.144148 · Cited by 556 · see citing works

Unusual repertoire of vocalizations in the BTBR T+tf/J mouse model of autism

Scattoni, M. L., Gandhy, S. U., Ricceri, L., & Crawley, J. N. (2008) · PLoS ONE · doi:10.1371/journal.pone.0003067 · Cited by 550 · see citing works

Mouse Behavioral Assays Relevant to the Symptoms of Autism*

Crawley, J. N. (2007) · Brain Pathology · doi:10.1111/j.1750-3639.2007.00096.x · Cited by 541 · cited 1× · see citing works

High resolution three-dimensional brain atlas using an average magnetic resonance image of 40 adult C57Bl/6J mice

Dorr, A. E., Lerch, J. P., Spring, S., Kabani, N. J., & Henkelman, R. M. (2008) · NeuroImage · doi:10.1016/j.neuroimage.2008.03.037 · Cited by 539 · see citing works

Towards a neuroanatomy of autism: A systematic review and meta-analysis of structural magnetic resonance imaging studies

Stanfield, A. C., McIntosh, A. M., Spencer, M. D., Philip, R., Gaur, S., & Lawrie, S. M. (2008) · European Psychiatry · doi:10.1016/j.eurpsy.2007.05.006 · Cited by 524 · see citing works

Cellular Mechanisms of Social Attachment

Young, L. J., Lim, M. M., Gingrich, B., & Insel, T. R. (2001) · Hormones and Behavior · doi:10.1006/hbeh.2001.1691 · Cited by 523 · see citing works

Diffusion tensor imaging in autism spectrum disorder: a review

Travers, B. G., Adluru, N., Ennis, C., Tromp, D. P. M., Destiche, D., Doran, S., Bigler, E. D., Lange, N., Lainhart, J. E., & Alexander, A. L. (2012) · Autism Research · doi:10.1002/aur.1243 · Cited by 450 · see citing works

Repetitive Self-Grooming Behavior in the BTBR Mouse Model of Autism is Blocked by the mGluR5 Antagonist MPEP

Silverman, J. L., Tolu, S. S., Barkan, C. L., & Crawley, J. N. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2009.201 · Cited by 438 · see citing works

Morphology, Molecular Codes, and Circuitry Produce the Three-Dimensional Complexity of the Cerebellum

Sillitoe, R. V., & Joyner, A. L. (2007) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.23.090506.123237 · Cited by 400 · see citing works

An MRI study of the basal ganglia in autism

Sears, L. L., Vest, C., Mohamed, S., Bailey, J., Ranson, B. J., & Piven, J. (1999) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/s0278-5846(99)00020-2 · Cited by 364 · see citing works

Unusual repertoire of vocalizations in adult BTBR T+tf/J mice during three types of social encounters

Scattoni, M. L., Ricceri, L., & Crawley, J. N. (2010) · Genes Brain & Behavior · doi:10.1111/j.1601-183x.2010.00623.x · Cited by 336 · see citing works

Dosage-dependent phenotypes in models of 16p11.2 lesions found in autism

Horev, G., Ellegood, J., Lerch, J. P., Son, Y.-E. E., Muthuswamy, L., Vogel, H., Krieger, A. M., Buja, A., Henkelman, R. M., Wigler, M., et al. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1114042108 · Cited by 330 · see citing works

Reduced Caudate Nucleus Volume in Obsessive-compulsive Disorder

Robinson, D. G. (1995) · Archives of General Psychiatry · doi:10.1001/archpsyc.1995.03950170067009 · Cited by 320 · see citing works

Maze training in mice induces MRI-detectable brain shape changes specific to the type of learning

Lerch, J. P., Yiu, A. P., Martinez-Canabal, A., Pekar, T., Bohbot, V. D., Frankland, P. W., Henkelman, R. M., Josselyn, S. A., & Sled, J. G. (2011) · NeuroImage · doi:10.1016/j.neuroimage.2010.09.086 · Cited by 300 · see citing works

A developmental study of the structural integrity of white matter in autism

Keller, T. A., Kana, R. K., & Just, M. A. (2007) · Neuroreport · doi:10.1097/01.wnr.0000239965.21685.99 · Cited by 300 · see citing works

Minimal aberrant behavioral phenotypes of neuroligin‐3 R451C knockin mice

Chadman, K. K., Gong, S., Scattoni, M. L., Boltuck, S. E., Gandhy, S. U., Heintz, N., & Crawley, J. N. (2008) · Autism Research · doi:10.1002/aur.22 · Cited by 292 · see citing works

A Meta-Analysis of the Corpus Callosum in Autism

Frazier, T. W., & Hardan, A. Y. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.07.022 · Cited by 267 · see citing works

The neurobiology of repetitive behavior: …and men

Langen, M., Durston, S., Kas, M. J., van Engeland, H., & Staal, W. (2010) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2010.02.005 · Cited by 266 · see citing works

Assessing autism-like behavior in mice: Variations in social interactions among inbred strains

BOLIVAR, V, WALTERS, S., & PHOENIX, J. (2007) · Behavioural Brain Research · doi:10.1016/j.bbr.2006.09.007 · Cited by 264 · see citing works

Negative allosteric modulation of the mGluR5 receptor reduces repetitive behaviors and rescues social deficits in mouse models of autism

Silverman, J. L., Smith, D. G., Rizzo, S. J. S., Karras, M. N., Turner, S. M., Tolu, S. S., Bryce, D. K., Smith, D. L., Fonseca, K., Ring, R. H., et al. (2012) · Science Translational Medicine · doi:10.1126/scitranslmed.3003501 · Cited by 251 · see citing works

Diffusion tensor imaging of the developing mouse brain

Mori, S., Itoh, R., Zhang, J., Kaufmann, W. E., van Zijl, P. C. M., Solaiyappan, M., & Yarowsky, P. (2001) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1155 · Cited by 236 · see citing works

The neurobiology of repetitive behavior: Of mice…

Langen, M., Kas, M. J., Staal, W., van Engeland, H., & Durston, S. (2010) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2010.02.004 · Cited by 223 · see citing works

Sociability and motor functions in Shank1 mutant mice

Silverman, J. L., Turner, S. M., Barkan, C. L., Tolu, S. S., Saxena, R., Hung, A. Y., Sheng, M., & Crawley, J. N. (2011) · Brain Research · doi:10.1016/j.brainres.2010.09.026 · Cited by 218 · see citing works

Survey of 21 inbred mouse strains in two laboratories reveals that BTBR T/+ tf/tf has severely reduced hippocampal commissure and absent corpus callosum

Wahlsten, D., Metten, P., & Crabbe, J. C. (2003) · Brain Research · doi:10.1016/s0006-8993(03)02354-0 · Cited by 206 · see citing works

Structural and functional magnetic resonance imaging of autism spectrum disorders

Stigler, K. A., McDonald, B. C., Anand, A., Saykin, A. J., & McDougle, C. J. (2011) · Brain Research · doi:10.1016/j.brainres.2010.11.076 · Cited by 197 · see citing works

Development of a mouse test for repetitive, restricted behaviors: Relevance to autism

Moy, S. S., Nadler, J. J., Poe, M. D., Nonneman, R. J., Young, N. B., Koller, B. H., Crawley, J. N., Duncan, G. E., & Bodfish, J. W. (2008) · Behavioural Brain Research · doi:10.1016/j.bbr.2007.10.029 · Cited by 195 · see citing works

Differences in BTBR T+ tf/J and C57BL/6J mice on probabilistic reversal learning and stereotyped behaviors

Amodeo, D. A., Jones, J. H., Sweeney, J. A., & Ragozzino, M. E. (2011) · Behavioural Brain Research · doi:10.1016/j.bbr.2011.10.032 · Cited by 191 · see citing works

Voxel-based meta-analysis of regional white-matter volume differences in autism spectrum disorder<i>versus</i>healthy controls

Radua, J., Via, E., Catani, M., & Mataix-Cols, D. (2011) · Psychological Medicine · doi:10.1017/s0033291710002187 · Cited by 183 · see citing works

Sexual dimorphism revealed in the structure of the mouse brain using three-dimensional magnetic resonance imaging

Spring, S., Lerch, J. P., & Henkelman, R. M. (2007) · NeuroImage · doi:10.1016/j.neuroimage.2007.02.023 · Cited by 180 · see citing works

The neurobiology of social recognition, approach, and avoidance

Young, L. J. (2002) · Biological Psychiatry · doi:10.1016/s0006-3223(01)01268-9 · Cited by 172 · see citing works

Motor and cognitive stereotypies in the BTBR T+tf/J mouse model of autism

Pearson, B. L., Pobbe, R. L. H., Defensor, E. B., Oasay, L., Bolivar, V. J., Blanchard, D. C., & Blanchard, R. J. (2011) · Genes, Brain and Behavior · doi:10.1111/j.1601-183x.2010.00659.x · Cited by 171 · see citing works

Neuroimaging of autism

Verhoeven, J. S., Cock, P. D., Lagae, L. G., & Sunaert, S. G. (2009) · Neuroradiology · doi:10.1007/s00234-009-0583-y · Cited by 171 · see citing works

Reduced scent marking and ultrasonic vocalizations in the BTBR T+tf/J mouse model of autism

Wöhr, M., Roullet, F. I., & Crawley, J. N. (2011) · Genes, Brain and Behavior · doi:10.1111/j.1601-183x.2010.00582.x · Cited by 169 · see citing works

Preparation of fixed mouse brains for MRI

Cahill, L. S., Laliberté, C. L., Ellegood, J., Spring, S., Gleave, J. A., van Eede, M. C., Lerch, J. P., & Henkelman, R. M. (2012) · NeuroImage · doi:10.1016/j.neuroimage.2012.01.100 · Cited by 153 · see citing works

Longitudinal neuroanatomical changes determined by deformation-based morphometry in a mouse model of Alzheimer's disease

Lau, J. C., Lerch, J. P., Sled, J. G., Henkelman, R. M., Evans, A. C., & Bedell, B. J. (2008) · NeuroImage · doi:10.1016/j.neuroimage.2008.04.252 · Cited by 151 · see citing works

Low stress reactivity and neuroendocrine factors in the BTBR T+tf/J mouse model of autism

Silverman, J. L., Yang, M., Turner, S. M., Katz, A. M., Bell, D. B., Koenig, J. I., & Crawley, J. N. (2010) · Neuroscience · doi:10.1016/j.neuroscience.2010.09.059 · Cited by 146 · see citing works

A novel social proximity test suggests patterns of social avoidance and gaze aversion-like behavior in BTBR T+ tf/J mice

Defensor, E. B., Pearson, B. L., Pobbe, R. L. H., Bolivar, V. J., Blanchard, D. C., & Blanchard, R. J. (2011) · Behavioural Brain Research · doi:10.1016/j.bbr.2010.10.033 · Cited by 136 · see citing works

MRI Phenotyping of Genetically Altered Mice

Lerch, J. P., Sled, J. G., & Henkelman, R. M. (2010) · Methods in molecular biology · doi:10.1007/978-1-61737-992-5_17 · Cited by 134 · see citing works

Cortical thickness measured from MRI in the YAC128 mouse model of Huntington's disease

Lerch, J. P., Carroll, J. B., Dorr, A. E., Spring, S., Evans, A. C., Hayden, M. R., Sled, J. G., & Henkelman, R. M. (2008) · NeuroImage · doi:10.1016/j.neuroimage.2008.02.019 · Cited by 133 · see citing works

Social deficits in BTBR <i>T</i> + <i>tf</i>/J mice are unchanged by cross‐fostering with C57BL/6J mothers

Yang, M., Zhodzishsky, V., & Crawley, J. N. (2007) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2007.09.008 · Cited by 132 · see citing works

Reduced ultrasonic vocalizations in vasopressin 1b knockout mice

Scattoni, M. L., McFarlane, H. G., Zhodzishsky, V., Caldwell, H. K., YOUNG, W., Ricceri, L., & Crawley, J. N. (2007) · Behavioural Brain Research · doi:10.1016/j.bbr.2007.09.034 · Cited by 131 · see citing works

Social approach behaviors are similar on conventional versus reverse lighting cycles, and in replications across cohorts, in BTBR T+ tf/J, C57BL/6J, and vasopressin receptor 1B mutant mice

Yang, M. (2007) · Frontiers in Behavioral Neuroscience · doi:10.3389/neuro.08.001.2007 · Cited by 124 · see citing works

Magnetic resonance histology for morphologic phenotyping

Johnson, G. A., Cofer, G. P., Fubara, B. N., Gewalt, S. L., Hedlund, L. W., & Maronpot, R. R. (2002) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.10175 · Cited by 122 · see citing works

Anatomical phenotyping in the brain and skull of a mutant mouse by magnetic resonance imaging and computed tomography

Nieman, B. J., Flenniken, A. M., Adamson, S. L., Henkelman, R. M., & Sled, J. G. (2006) · Physiological Genomics · doi:10.1152/physiolgenomics.00217.2005 · Cited by 122 · see citing works

Expression of social behaviors of C57BL/6J versus BTBR inbred mouse strains in the visible burrow system

Pobbe, R. L. H., Pearson, B. L., Defensor, E. B., Bolivar, V. J., Blanchard, D. C., & Blanchard, R. J. (2010) · Behavioural Brain Research · doi:10.1016/j.bbr.2010.06.025 · Cited by 121 · see citing works

Axonal Growth and Guidance Defects inFrizzled3Knock-Out Mice: A Comparison of Diffusion Tensor Magnetic Resonance Imaging, Neurofilament Staining, and Genetically Directed Cell Labeling

Wang, Y., Zhang, J., Mori, S., & Nathans, J. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.3221-05.2006 · Cited by 117 · see citing works

Postnatal lesion evidence against a primary role for the corpus callosum in mouse sociability

Yang, M., Clarke, A. M., & Crawley, J. N. (2009) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2009.06714.x · Cited by 117 · see citing works

General and social anxiety in the BTBR T+ tf/J mouse strain

Pobbe, R. L. H., Defensor, E. B., Pearson, B. L., Bolivar, V. J., Blanchard, D. C., & Blanchard, R. J. (2010) · Behavioural Brain Research · doi:10.1016/j.bbr.2010.08.039 · Cited by 115 · see citing works

Low sociability in BTBR T+tf/J mice is independent of partner strain

Yang, M., Abrams, D. N., Zhang, J. Y., Weber, M. D., Katz, A. M., Clarke, A. M., Silverman, J. L., & Crawley, J. N. (2012) · Physiology &amp; Behavior · doi:10.1016/j.physbeh.2011.12.025 · Cited by 112 · see citing works

Autism Attenuates Sex Differences in Brain Structure: A Combined Voxel-Based Morphometry and Diffusion Tensor Imaging Study

Beacher, F. D. C. C., Minati, L., Baron‐Cohen, S., Lombardo, M. V., Lai, M., Gray, M. A., Harrison, N. A., & Critchley, H. (2011) · American Journal of Neuroradiology · doi:10.3174/ajnr.a2880 · Cited by 111 · see citing works

Anatomical phenotyping in a mouse model of fragile X syndrome with magnetic resonance imaging

Ellegood, J., Pacey, L. K. K., Hampson, D. R., Lerch, J. P., & Henkelman, R. M. (2010) · NeuroImage · doi:10.1016/j.neuroimage.2010.03.038 · Cited by 110 · see citing works

Impaired Structural Connectivity of Socio-Emotional Circuits in Autism Spectrum Disorders: A Diffusion Tensor Imaging Study

Ameis, S. H., Fan, J., Rockel, C. P., Voineskos, A. N., Lobaugh, N. J., Soorya, L. V., Wang, A. T., Hollander, E., & Anagnostou, E. A. (2011) · PLoS ONE · doi:10.1371/journal.pone.0028044 · Cited by 110 · see citing works

Social peers rescue autism‐relevant sociability deficits in adolescent mice

Yang, M., Perry, K., Weber, M. D., Katz, A. M., & Crawley, J. N. (2011) · Autism Research · doi:10.1002/aur.163 · Cited by 106 · see citing works

Fluoxetine but not risperidone increases sociability in the BTBR mouse model of autism

Chadman, K. K. (2010) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2010.09.012 · Cited by 104 · see citing works

Female urine-induced male mice ultrasonic vocalizations, but not scent-marking, is modulated by social experience

Roullet, F., Wöhr, M., & Crawley, J. N. (2010) · Behavioural Brain Research · doi:10.1016/j.bbr.2010.06.004 · Cited by 97 · see citing works

Three-Dimensional Diffusion Tensor Magnetic Resonance Microimaging of Adult Mouse Brain and Hippocampus

Zhang, J., van Zijl, P. C. M., & Mori, S. (2002) · NeuroImage · doi:10.1006/nimg.2001.1012 · Cited by 96 · see citing works

A Two-Year Longitudinal MRI Study of the Corpus Callosum in Autism

Frazier, T. W., Keshavan, M. S., Minshew, N. J., & Hardan, A. Y. (2012) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-012-1478-z · Cited by 81 · see citing works

Brain abnormalities in a Neuroligin3 R451C knockin mouse model associated with autism

Ellegood, J., Lerch, J. P., & Henkelman, R. M. (2011) · Autism Research · doi:10.1002/aur.215 · Cited by 70 · see citing works

Magnetic resonance imaging for detection and analysis of mouse phenotypes

Nieman, B. J., Bock, N. A., Bishop, J., Chen, X., Sled, J. G., Rossant, J., & Henkelman, R. M. (2005) · NMR in Biomedicine · doi:10.1002/nbm.981 · Cited by 69 · see citing works

Quantitative analysis of the shape of the corpus callosum in patients with autism and comparison individuals

Casanova, M. F., El-Baz, A. S., Elnakib, A. A., Switala, A. E., Williams, E. L., Williams, D. L., Minshew, N. J., & Conturo, T. E. (2011) · Autism · doi:10.1177/1362361310386506 · Cited by 66 · see citing works

Diffusion Tensor Magnetic Resonance Imaging and Tract-Tracing Analysis of Probst Bundle Structure in Netrin1- and DCC-Deficient Mice

Ren, T., Zhang, J., Plachez, C., Mori, S., & Richards, L. J. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.2787-07.2007 · Cited by 63 · see citing works

Multiple mouse biological loading and monitoring system for MRI

Dazai, J., Bock, N. A., Nieman, B. J., Davidson, L., Henkelman, R. M., & Chen, X. (2004) · Magnetic Resonance in Medicine · doi:10.1002/mrm.20215 · Cited by 63 · see citing works

Magnetic resonance microscopy‐based analyses of the brains of normal and ethanol‐exposed fetal mice

O’Leary‐Moore, S. K., Parnell, S. E., Godin, E. A., Dehart, D. B., Ament, J. J., Khan, A. A., Johnson, G. A., Styner, M. A., & Sulik, K. K. (2010) · Birth Defects Research Part A Clinical and Molecular Teratology · doi:10.1002/bdra.20719 · Cited by 61 · see citing works

High‐resolution fast spin echo imaging of the human brain at 4.7 T: Implementation and sequence characteristics

Thomas, D. L., Vita, E. D., Roberts, S., Turner, R., Yousry, T. A., & Ordidge, R. J. (2004) · Magnetic Resonance in Medicine · doi:10.1002/mrm.20106 · Cited by 54 · see citing works

Neuroanatomical Assessment of the Integrin β3 Mouse Model Related to Autism and the Serotonin System Using High Resolution MRI

Ellegood, J., Henkelman, R. M., & Lerch, J. P. (2012) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2012.00037 · Cited by 51 · see citing works

Magnetic resonance imaging at microscopic resolution reveals subtle morphological changes in a mouse model of dopaminergic hyperfunction

Cyr, M., Caron, M. G., Johnson, G. A., & Laakso, A. (2005) · NeuroImage · doi:10.1016/j.neuroimage.2005.01.039 · Cited by 50 · see citing works

FVB.129P2‐Pde6b+ Tyrc‐ch/Ant, a sighted variant of the FVB/N mouse strain suitable for behavioral analysis

Errijgers, V., Dam, D. V., Gantois, I., Ginneken, C. J. V., Grossman, A. W., D’Hooge, R., Deyn, P. P. D., & Kooy, R. F. (2006) · Genes Brain & Behavior · doi:10.1111/j.1601-183x.2006.00282.x · Cited by 47 · see citing works

Cerebral asymmetries in 12-week-old C57Bl/6J mice measured by magnetic resonance imaging

Spring, S., Lerch, J. P., Wetzel, M. K., Evans, A. C., & Henkelman, R. M. (2009) · NeuroImage · doi:10.1016/j.neuroimage.2009.12.043 · Cited by 47 · see citing works

MR technology for biological studies in mice

Nieman, B. J., Bishop, J. E., Dazai, J., Bock, N. A., Lerch, J. P., Feintuch, A., Chen, X., Sled, J. G., & Henkelman, R. M. (2007) · NMR in Biomedicine · doi:10.1002/nbm.1142 · Cited by 41 · see citing works

Longitudinal in-vivo diffusion tensor imaging for assessing brain developmental changes in BALB/cJ mice, a model of reduced sociability relevant to autism

Kumar, M., Kim, S., Pickup, S., Chen, R., Fairless, A. H., Ittyerah, R., Abel, T. G., Brodkin, E. S., & Poptani, H. (2012) · Brain Research · doi:10.1016/j.brainres.2012.03.041 · Cited by 35 · see citing works

Model of Huntington's Disease

Davies, S. W., & Roberts, P. J. J. (1988) · Science · doi:10.1126/science.2969147 · Cited by 25 · see citing works

Anisotropic and restricted diffusion of water in the sciatic nerve: A 2H double‐quantum‐filtered NMR study

Seo, Y., Shinar, H., Morita, Y., & Navon, G. (1999) · Magnetic Resonance in Medicine · doi:10.1002/(sici)1522-2594(199909)42:3 · Cited by 19 · see citing works

Autism spectrum disorder: neuropathology and animal models

Varghese, M., Keshav, N., Jacot-Descombes, S., Warda, T., Wicinski, B., Dickstein, D. L., Harony-Nicolas, H., De Rubeis, S., Drapeau, E., Buxbaum, J. D., et al. (2017) · Acta Neuropathologica · doi:10.1007/s00401-017-1736-4 · Cited by 536 · see citing works

Negative symptoms of schizophrenia: Clinical characteristics, pathophysiological substrates, experimental models and prospects for improved treatment

Millan, M. J., Fone, K. C. F., Steckler, T., & Horan, W. P. (2014) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2014.03.008 · Cited by 354 · see citing works

Clustering autism: using neuroanatomical differences in 26 mouse models to gain insight into the heterogeneity

Ellegood, J., Anagnostou, E., Babineau, B. A., Crawley, J. N., Lin, L., Genestine, M., DiCicco-Bloom, E., Lai, J. K. Y., Foster, J. A., Peñagarikano, O., et al. (2015) · Molecular Psychiatry · doi:10.1038/mp.2014.98 · Cited by 288 · see citing works

Behavioral abnormalities and circuit defects in the basal ganglia of a mouse model of 16p11.2 deletion syndrome

Portmann, T., Yang, M., Mao, R., Panagiotakos, G., Ellegood, J., Dolen, G., Bader, P. L., Grueter, B. A., Goold, C., Fisher, E., et al. (2014) · Cell Reports · doi:10.1016/j.celrep.2014.03.036 · Cited by 245 · see citing works

Enhancement of Inhibitory Neurotransmission by GABA A Receptors Having α 2,3 -Subunits Ameliorates Behavioral Deficits in a Mouse Model of Autism

Han, S., Tai, C., Jones, C. J., Scheuer, T., & Catterall, W. A. (2014) · Neuron · doi:10.1016/j.neuron.2014.01.016 · Cited by 231 · see citing works

Acetylcholine Elevation Relieves Cognitive Rigidity and Social Deficiency in a Mouse Model of Autism

Karvat, G., & Kimchi, T. (2013) · Neuropsychopharmacology · doi:10.1038/npp.2013.274 · Cited by 203 · see citing works

The BTBR mouse model of idiopathic autism – Current view on mechanisms

Meyza, K. Z., & Blanchard, D. C. (2017) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.12.037 · Cited by 189 · see citing works

Imaging sex/gender and autism in the brain: Etiological implications

Lai, M., Lerch, J. P., Floris, D. L., Ruigrok, A. N. V., Pohl, A. L., Lombardo, M. V., & Baron‐Cohen, S. (2016) · Journal of Neuroscience Research · doi:10.1002/jnr.23948 · Cited by 134 · see citing works

Behavioral and Neuroanatomical Phenotypes in Mouse Models of Autism

Ellegood, J., & Crawley, J. N. (2015) · Neurotherapeutics · doi:10.1007/s13311-015-0360-z · Cited by 132 · see citing works

Neuroimaging Evidence of Major Morpho-Anatomical and Functional Abnormalities in the BTBR T+TF/J Mouse Model of Autism

Dodero, L., Damiano, M., Galbusera, A., Bifone, A., Tsaftsaris, S. A., Scattoni, M. L., & Gozzi, A. (2013) · PLoS ONE · doi:10.1371/journal.pone.0076655 · Cited by 116 · see citing works

Pydpiper: a flexible toolkit for constructing novel registration pipelines

Friedel, M., van Eede, M. C., Pipitone, J., Chakravarty, M. M., & Lerch, J. P. (2014) · Frontiers in Neuroinformatics · doi:10.3389/fninf.2014.00067 · Cited by 121 · see citing works

ERK/MAPK signaling and autism spectrum disorders

Vithayathil, J., Pucilowska, J., & Landreth, G. E. (2018) · Progress in brain research · doi:10.1016/bs.pbr.2018.09.008 · Cited by 101 · see citing works

Neural Mechanisms Underlying Repetitive Behaviors in Rodent Models of Autism Spectrum Disorders

Gandhi, T., & Lee, C. C. (2021) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2020.592710 · Cited by 94 · see citing works

Mesenchymal Stem Cell Transplantation Promotes Neurogenesis and Ameliorates Autism Related Behaviors in BTBR Mice

Segal‐Gavish, H., Karvat, G., Barak, N., Barzilay, R., Ganz, J., Edry, L., Aharony, I., Offen, D., & Kimchi, T. (2015) · Autism Research · doi:10.1002/aur.1530 · Cited by 93 · see citing works

Species-conserved SYNGAP1 phenotypes associated with neurodevelopmental disorders

Kılınç, M., Creson, T. K., Rojas, C., Aceti, M., Ellegood, J., Vaissière, T., Lerch, J. P., & Rumbaugh, G. (2018) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2018.03.008 · Cited by 81 · see citing works

Neuronal overexpression of Ube3a isoform 2 causes behavioral impairments and neuroanatomical pathology relevant to 15q11.2-q13.3 duplication syndrome

Copping, N. A., Christian, S., Ritter, D., Islam, M. S., Buscher, N., Żółkowska, D., Pride, M. C., Berg, E. L., LaSalle, J. M., Ellegood, J., et al. (2017) · Human Molecular Genetics · doi:10.1093/hmg/ddx289 · Cited by 88 · see citing works

An Evo-Devo Approach to Thyroid Hormones in Cerebral and Cerebellar Cortical Development: Etiological Implications for Autism

Berbel, P. J., Navarro, D., & Román, G. C. (2014) · Frontiers in Endocrinology · doi:10.3389/fendo.2014.00146 · Cited by 85 · see citing works

Hippocampal deficits in neurodevelopmental disorders

Li, Y., Shen, M., Stockton, M. E., & Zhao, X. (2018) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2018.10.001 · Cited by 84 · see citing works

Understanding autism spectrum disorders with animal models: applications, insights, and perspectives

Zhu, L., 昆明650500，中国, 云., Zhu, Y., Gu, L., & Cheng, Y. (2021) · 动物学研究 · doi:10.24272/j.issn.2095-8137.2021.251 · Cited by 84 · see citing works

Label-free photoacoustic tomography of whole mouse brain structures ex vivo

Li, L. S., Xia, J., Li, G., Garcia‐Uribe, A., Sheng, Q., Anastasio, M. A., & Wang, L. V. (2016) · Neurophotonics · doi:10.1117/1.nph.3.3.035001 · Cited by 70 · see citing works

Semi-automated registration-based anatomical labelling, voxel based morphometry and cortical thickness mapping of the mouse brain

Pagani, M., Damiano, M., Galbusera, A., Tsaftaris, S. A., & Gozzi, A. (2016) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2016.04.007 · Cited by 60 · see citing works

Mapk/Erk activation in an animal model of social deficits shows a possible link to autism

Faridar, A., Jones-Davis, D., Rider, E., Li, J., Gobius, I., Morcom, L., Richards, L. J., Sen, S., & Sherr, E. H. (2014) · Molecular Autism · doi:10.1186/2040-2392-5-57 · Cited by 63 · see citing works

The neural circuitry of restricted repetitive behavior: Magnetic resonance imaging in neurodevelopmental disorders and animal models

Wilkes, B. J., & Lewis, M. H. (2018) · Neuroscience &amp; Biobehavioral Reviews · doi:10.1016/j.neubiorev.2018.05.022 · Cited by 64 · see citing works

Altered dopaminergic pathways and therapeutic effects of intranasal dopamine in two distinct mouse models of autism

Chao, O. Y.-H., Pathak, S. S., Zhang, H., Dunaway, N., Li, J., Mattern, C., Nikolaus, S., Huston, J. P., & Yang, Y. (2020) · Molecular Brain · doi:10.1186/s13041-020-00649-7 · Cited by 62 · see citing works

White and Gray Matter Abnormalities After Cranial Radiation in Children and Mice

Nieman, B. J., de Guzman, A. E., Gazdzinski, L. M., Lerch, J. P., Chakravarty, M. M., Pipitone, J., Strother, D., Fryer, C., Bouffet, E., Laughlin, S., et al. (2015) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/j.ijrobp.2015.07.2293 · Cited by 62 · see citing works

Automated pipeline for anatomical phenotyping of mouse embryos using micro-CT

Wong, M. D., Maezawa, Y., Lerch, J. P., & Henkelman, R. M. (2014) · Development · doi:10.1242/dev.107722 · Cited by 62 · see citing works

Formation of functional areas in the cerebral cortex is disrupted in a mouse model of autism spectrum disorder

Fenlon, L. R., Liu, S., Gobius, I., Kurniawan, N. D., Murphy, S. J., Moldrich, R. X., & Richards, L. J. (2015) · Neural Development · doi:10.1186/s13064-015-0033-y · Cited by 58 · see citing works

Precocious myelination in a mouse model of autism

Khanbabaei, M., Hughes, E., Ellegood, J., Qiu, L. R., Yip, R., Dobry, J., Murari, K., Lerch, J. P., Rho, J. M., & Cheng, N. (2019) · Translational Psychiatry · doi:10.1038/s41398-019-0590-7 · Cited by 57 · see citing works

Comparison of in vivo and ex vivo MRI for the detection of structural abnormalities in a mouse model of tauopathy

Holmes, H. E., Powell, N. M., Ma, D., Ismail, O., Harrison, I. F., Wells, J. A., Colgan, N., O'Callaghan, J. M., Johnson, R. A., Murray, T. K., et al. (2017) · Frontiers in Neuroinformatics · doi:10.3389/fninf.2017.00020 · Cited by 55 · see citing works

Developmental Disruptions of the Dorsal Striatum in Autism Spectrum Disorder

Evans, M. M., Kim, J., Abel, T. G., Nickl‐Jockschat, T., & Stevens, H. E. (2023) · Biological Psychiatry · doi:10.1016/j.biopsych.2023.08.015 · Cited by 49 · see citing works

Tet1 oxidase regulates neuronal gene transcription, active DNA hydroxymethylation, object location memory, and threat recognition memory

Kumar, D. B. U., Aggarwal, M., Kaas, G. A., Lewis, J., Wang, J., Ross, D. L., Zhong, C., Kennedy, A. J., Song, H., & Sweatt, J. D. (2015) · Neuroepigenetics · doi:10.1016/j.nepig.2015.10.002 · Cited by 51 · see citing works

Behavioral assessments of BTBR T+Itpr3tf/J mice by tests of object attention and elevated open platform: Implications for an animal model of psychiatric comorbidity in autism

Chao, O. Y.-H., Yunger, R., & Yang, Y. (2018) · Behavioural Brain Research · doi:10.1016/j.bbr.2018.03.014 · Cited by 51 · see citing works

Variability and heritability of mouse brain structure: Microscopic MRI atlases and connectomes for diverse strains

Wang, N., Anderson, R. J., Ashbrook, D. G., Gopalakrishnan, V., Park, Y., Priebe, C. E., Qi, Y. P., Laoprasert, R., Vogelstein, J. T., Williams, R. W., et al. (2020) · NeuroImage · doi:10.1016/j.neuroimage.2020.117274 · Cited by 51 · see citing works

Cognitive Abilities on Transitive Inference Using a Novel Touchscreen Technology for Mice

Silverman, J. L., Gastrell, P. T., Karras, M. N., Solomon, M., & Crawley, J. N. (2013) · Cerebral Cortex · doi:10.1093/cercor/bht293 · Cited by 49 · see citing works

Genetic modifications associated with ketogenic diet treatment in the BTBR^T+Tf/J mouse model of autism spectrum disorder

Mychasiuk, R., & Rho, J. M. (2017) · Autism Research · doi:10.1002/aur.1682 · Cited by 45 · see citing works

Microwave‐induced thermoacoustic tomography through an adult human skull

An, Y., Lin, L., Liu, C., Shi, J., Na, S., & Wang, L. V. (2019) · Medical Physics · doi:10.1002/mp.13439 · Cited by 47 · see citing works

Non-diagnostic symptoms in a mouse model of autism in relation to neuroanatomy: the BTBR strain reinvestigated

Faraji, J., Karimi, M., Lawrence, C., Mohajerani, M. H., & Metz, G. A. S. (2018) · Translational Psychiatry · doi:10.1038/s41398-018-0280-x · Cited by 46 · see citing works

Regional brain volumes changes in adult male FMR1-KO mouse on the FVB strain

Lai, J., Lerch, J. P., Doering, L. C., Foster, J. A., & Ellegood, J. (2016) · Neuroscience · doi:10.1016/j.neuroscience.2016.01.021 · Cited by 45 · see citing works

Neuronal nitric oxide synthase and NADPH oxidase interact to affect cognitive, affective, and social behaviors in mice

Walton, J. C., Selvakumar, B., Weil, Z. M., Snyder, S. H., & Nelson, R. J. (2013) · Behavioural Brain Research · doi:10.1016/j.bbr.2013.08.003 · Cited by 44 · see citing works

Proteomic analysis of cortical brain tissue from the BTBR mouse model of autism: Evidence for changes in STOP and myelin-related proteins

Wei, H., Ma, Y., Liu, J., Ding, C., Hu, F., & Li, Y. (2015) · Neuroscience · doi:10.1016/j.neuroscience.2015.11.003 · Cited by 44 · see citing works

Effect of social odor context on the emission of isolation-induced ultrasonic vocalizations in the BTBR T+tf/J mouse model for autism

Wöhr, M. (2015) · Frontiers in Neuroscience · doi:10.3389/fnins.2015.00073 · Cited by 43 · see citing works

Validation of operant social motivation paradigms using BTBR T+tf/J and C57 BL /6J inbred mouse strains

Martin, L. A., Sample, H. A., Gregg, M., & Wood, C. A. (2014) · Brain and Behavior · doi:10.1002/brb3.273 · Cited by 43 · see citing works

Oxytocin and serotonin in the modulation of neural function: Neurobiological underpinnings of autism-related behavior

Zhao, F., Zhang, H., Wang, P., Cui, W., Xu, K., Chen, D., Hu, M., Li, Z., Geng, X., & Wei, S. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.919890 · Cited by 42 · see citing works

Home-cage hypoactivity in mouse genetic models of autism spectrum disorder

Angelakos, C. C., Tudor, J. C., Ferri, S. L., Jongens, T. A., & Abel, T. G. (2019) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2019.02.010 · Cited by 42 · see citing works

Dendritic overgrowth and elevated ERK signaling during neonatal development in a mouse model of autism

Cheng, N., Alshammari, F., Hughes, E., Khanbabaei, M., & Rho, J. M. (2017) · PLoS ONE · doi:10.1371/journal.pone.0179409 · Cited by 39 · see citing works

Targeting inhibitory cerebellar circuitry to alleviate behavioral deficits in a mouse model for studying idiopathic autism

Chao, O. Y.-H., de Velasco, E. M. F., Pathak, S. S., Maitra, S., Zhang, H., Duvick, L. A., Wickman, K., Orr, H. T., Hirai, H., & Yang, Y. (2020) · Neuropsychopharmacology · doi:10.1038/s41386-020-0656-5 · Cited by 51 · see citing works

Voxel-based morphometry analyses of in vivo MRI in the aging mouse lemur primate

Sawiak, S. J., Picq, J., & Dhénain, M. (2014) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2014.00082 · Cited by 37 · see citing works

Loss of T cells influences sex differences in behavior and brain structure

Rilett, K. C., Friedel, M., Ellegood, J., MacKenzie, R. N., Lerch, J. P., & Foster, J. A. (2015) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2015.02.016 · Cited by 37 · see citing works

Behavioral and neuroanatomical approaches in models of neurodevelopmental disorders: opportunities for translation

Silverman, J. L., & Ellegood, J. (2018) · Current Opinion in Neurology · doi:10.1097/wco.0000000000000537 · Cited by 35 · see citing works

Whole mouse brain connectomics

Johnson, G. A., Wang, N., Anderson, R. J., Chen, M., Cofer, G. P., Gee, J. C., Pratson, F., Tustison, N. J., & WHITE, L. E. (2018) · The Journal of Comparative Neurology · doi:10.1002/cne.24560 · Cited by 35 · see citing works

The γ-Protocadherins Regulate the Survival of GABAergic Interneurons during Developmental Cell Death

Carriere, C. H., Wang, W. X., Sing, A. D., Fekete, Á., Jones, B. E., Yee, Y., Ellegood, J., Maganti, H. B., Awofala, L., Marocha, J., et al. (2020) · Journal of Neuroscience · doi:10.1523/jneurosci.1636-20.2020 · Cited by 37 · see citing works

Chronic Anatabine Treatment Reduces Alzheimer’s Disease (AD)-Like Pathology and Improves Socio-Behavioral Deficits in a Transgenic Mouse Model of AD

Verma, M., Beaulieu‐Abdelahad, D., Ait‐Ghezala, G., Li, R., Crawford, F., MULLAN, M. J., & Paris, D. (2015) · PLoS ONE · doi:10.1371/journal.pone.0128224 · Cited by 36 · see citing works

A recurrent SHANK1 mutation implicated in autism spectrum disorder causes autistic-like core behaviors in mice via downregulation of mGluR1-IP3R1-calcium signaling

Qin, Y., Du, Y., Chen, L., Liu, Y., Xu, W., Liu, Y., Li, Y., Leng, J., Wang, Y., Zhang, X., et al. (2022) · Molecular Psychiatry · doi:10.1038/s41380-022-01539-1 · Cited by 34 · see citing works

High Resolution Magnetic Resonance Imaging for Characterization of the Neuroligin-3 Knock-in Mouse Model Associated with Autism Spectrum Disorder

Kumar, M., Duda, J., Hwang, W., Kenworthy, C. A., Ittyerah, R., Pickup, S., Brodkin, E. S., Gee, J. C., Abel, T. G., & Poptani, H. (2014) · PLoS ONE · doi:10.1371/journal.pone.0109872 · Cited by 33 · see citing works

Shank3 Transgenic and Prenatal Zinc-Deficient Autism Mouse Models Show Convergent and Individual Alterations of Brain Structures in MRI

Schoen, M., Asoglu, H., Bauer, H. F., Müller, H., Abaei, A., Sauer, A. K., Zhang, R., Song, T.-J., Bockmann, J., Kassubek, J., et al. (2019) · Frontiers in Neural Circuits · doi:10.3389/fncir.2019.00006 · Cited by 33 · see citing works

Comorbid epilepsy in autism spectrum disorder: Implications of postnatal inflammation for brain excitability

Lewis, M. L., Kesler, M., Candy, S., Rho, J. M., & Pittman, Q. J. (2018) · Epilepsia · doi:10.1111/epi.14440 · Cited by 31 · see citing works

Neuroanatomical Phenotypes Are Consistent With Autism‐Like Behavioral Phenotypes in the 15q11‐13 Duplication Mouse Model

Ellegood, J., Nakai, N., Nakatani, J., Henkelman, R. M., Takumi, T., & Lerch, J. P. (2015) · Autism Research · doi:10.1002/aur.1469 · Cited by 30 · see citing works

Brain-Derived Neurotrophic Factor (BDNF) in Mechanisms of Autistic-like Behavior in BTBR Mice: Crosstalk with the Dopaminergic Brain System

Ilchibaeva, T. V., Tsybko, A. S., Lipnitskaya, M., Eremin, D. V., Milutinovich, K. S., Naumenko, V. S., & Popova, N. K. (2023) · Biomedicines · doi:10.3390/biomedicines11051482 · Cited by 29 · see citing works

Chd8 mutation in oligodendrocytes alters microstructure and functional connectivity in the mouse brain

Kawamura, A., Abe, Y., Seki, F., Katayama, Y., Nishiyama, M., Takata, N., Tanaka, K. F., Okano, H., & Nakayama, K. I. (2020) · Molecular Brain · doi:10.1186/s13041-020-00699-x · Cited by 22 · see citing works

Metformin effects on brain development following cranial irradiation in a mouse model

Yuen, N., Szulc, K. U., Li, Y.-Q., Morshead, C. M., Mabbott, D., Wong, C. S., & Nieman, B. J. (2021) · Neuro-Oncology · doi:10.1093/neuonc/noab131 · Cited by 22 · see citing works

Touchscreen cognitive deficits, hyperexcitability and hyperactivity in males and females using two models ofCdkl5deficiency

Adhikari, A., Buchanan, F. K. B., Fenton, T. A., Cameron, D. L., Halmai, J. A. N. M., Copping, N. A., Fink, K. D., & Silverman, J. L. (2022) · Human Molecular Genetics · doi:10.1093/hmg/ddac091 · Cited by 22 · see citing works

Reduced Glutamate Release in Adult BTBR Mouse Model of Autism Spectrum Disorder

Wei, H., Ma, Y., Ding, C., Jin, G., Liu, J., Chang, Q., Hu, F., & Li, Y. (2016) · Neurochemical Research · doi:10.1007/s11064-016-2035-5 · Cited by 22 · see citing works

Volumetric magnetic resonance and diffusion tensor imaging of C58/J mice: neural correlates of repetitive behavior

Wilkes, B. J., Bass, C., Korah, H. E., Febo, M., & Lewis, M. H. (2019) · Brain Imaging and Behavior · doi:10.1007/s11682-019-00158-9 · Cited by 22 · see citing works

Spatial gene expression analysis of neuroanatomical differences in mouse models

Fernandes, D., Ellegood, J., Askalan, R., Blakely, R., DiCicco-Bloom, E. M., Egan, S. E., Osborne, L. R., Powell, C. M., Raznahan, A., Robins, D. M., et al. (2017) · NeuroImage · doi:10.1016/j.neuroimage.2017.08.065 · Cited by 21 · see citing works

Somatosensorimotor and Odor Modification, Along with Serotonergic Processes Underlying the Social Deficits in BTBR T+ Itpr3tf/J and BALB/cJ Mouse Models of Autism

Arakawa, H. (2020) · Neuroscience · doi:10.1016/j.neuroscience.2020.02.002 · Cited by 20 · see citing works

Cross-translational models of late-onset cognitive sequelae and their treatment in pediatric brain tumor survivors

Dahhan, N. Z. A., Cox, E., Nieman, B. J., & Mabbott, D. (2022) · Neuron · doi:10.1016/j.neuron.2022.04.009 · Cited by 21 · see citing works

Multimodal Neuroimaging in Rett Syndrome With MECP2 Mutation

Kong, Y., Li, Q.-B., Zhao-hong, Y., Jiang, X., Zhang, G.-Q., Cheng, N., & Dang, N. (2022) · Frontiers in Neurology · doi:10.3389/fneur.2022.838206 · Cited by 19 · see citing works

Analysis of neuroanatomical differences in mice with genetically modified serotonin transporters assessed by structural magnetic resonance imaging

Ellegood, J., Yee, Y., Kerr, T. M., Muller, C. L., Blakely, R., Henkelman, R. M., Veenstra-VanderWeele, J. M., & Lerch, J. P. (2018) · Molecular Autism · doi:10.1186/s13229-018-0210-z · Cited by 17 · see citing works

Heterozygosity for Nuclear Factor One X in mice models features of Malan syndrome

Oishi, S., Harkins, D., Kurniawan, N. D., Kasherman, M. A., Harris, L., Zalucki, O. H., Gronostajski, R. M., Burne, T. H. J., & Piper, M. (2018) · EBioMedicine · doi:10.1016/j.ebiom.2018.11.044 · Cited by 17 · see citing works

Diffusion functional MRI reveals global brain network functional abnormalities driven by targeted local activity in a neuropsychiatric disease mouse model

Abe, Y., Takata, N., Sakai, Y., Hamada, H. T., Hiraoka, Y., Aida, T., Tanaka, K., Bihan, D. L., Doya, K., & Tanaka, K. F. (2020) · NeuroImage · doi:10.1016/j.neuroimage.2020.117318 · Cited by 17 · see citing works

Comprehensive Profiling of Gene Expression in the Cerebral Cortex and Striatum of BTBRTF/ArtRbrc Mice Compared to C57BL/6J Mice

Mizuno, S., Hirota, J.-N., Ishii, C., Iwasaki, H., Sano, Y., & Furuichi, T. (2020) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2020.595607 · Cited by 18 · see citing works

Normothermic Mouse Functional MRI of Acute Focal Thermostimulation for Probing Nociception

Reimann, H. M., Hentschel, J., Marek, J., Huelnhagen, T., Todiraş, M., Kox, S., Waiczies, S., Hodge, R., Bäder, M., Pohlmann, A., et al. (2016) · Scientific Reports · doi:10.1038/srep17230 · Cited by 16 · see citing works

Disruption of visual circuit formation and refinement in a mouse model of autism

Cheng, N., Khanbabaei, M., Murari, K., & Rho, J. M. (2016) · Autism Research · doi:10.1002/aur.1687 · Cited by 16 · see citing works

Mapping the living mouse brain neural architecture: strain-specific patterns of brain structural and functional connectivity

Karatas, M., Noblet, V., Nasseef, M. T., Bienert, T., Reisert, M., Hennig, J., Yalçın, İ., Kieffer, B. L., von Elverfeldt, D., & Harsan, L. A. (2021) · Brain Structure and Function · doi:10.1007/s00429-020-02190-8 · Cited by 18 · see citing works

Molecular Abnormalities in BTBR Mice and Their Relevance to Schizophrenia and Autism Spectrum Disorders: An Overview of Transcriptomic and Proteomic Studies

Kisaretova, P. E., Tsybko, A. S., Bondar, N. P., & Reshetnikov, V. V. (2023) · Biomedicines · doi:10.3390/biomedicines11020289 · Cited by 15 · see citing works

Investigating brain–gut microbiota dynamics and inflammatory processes in an autistic-like rat model using MRI biomarkers during childhood and adolescence

Palanivelu, L., Chen, Y., Chang, C., Liang, Y., Tseng, H.-Y., Li, S., Chang, C., & Lo, Y. (2024) · NeuroImage · doi:10.1016/j.neuroimage.2024.120899 · Cited by 15 · see citing works

The within-subject application of diffusion tensor MRI and CLARITY reveals brain structural changes in Nrxn2 deletion mice

Pervolaraki, E., Tyson, A. L., Pibiri, F., Poulter, S. L., Reichelt, A. C., Rodgers, R. J., Clapcote, S. J., Lever, C., Andreae, L. C., & Dachtler, J. (2019) · Molecular Autism · doi:10.1186/s13229-019-0261-9 · Cited by 16 · see citing works

Elevated lysine crotonylation and succinylation in the brains of BTBR mice

Wang, M., Chang, Q., Yang, H., Liu, Y., Wang, C., Hu, F., Wei, H., & Li, R. (2019) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2019.06.011 · Cited by 14 · see citing works

Molecular Pathways, Neural Circuits and Emerging Therapies for Self-Injurious Behaviour

Zhang, K., Ibrahim, G. M., & Gouveia, F. V. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26051938 · Cited by 14 · see citing works

An old model with new insights: endogenous retroviruses drive the evolvement toward ASD susceptibility and hijack transcription machinery during development

Lin, C.-W., Ellegood, J., Tamada, K., Miura, I., Konda, M., Takeshita, K., Atarashi, K., Lerch, J. P., Wakana, S., McHugh, T. J., et al. (2023) · Molecular Psychiatry · doi:10.1038/s41380-023-01999-z · Cited by 13 · see citing works

Examining the effect of chronic intranasal oxytocin administration on the neuroanatomy and behavior of three autism-related mouse models

Lindenmaier, Z., Ellegood, J., Stuive, M., Easson, K., Yee, Y., Fernandes, D., Foster, J. A., Anagnostou, E. A., & Lerch, J. P. (2022) · NeuroImage · doi:10.1016/j.neuroimage.2022.119243 · Cited by 12 · see citing works

Auditory Processing Enhancements in the TS2-Neo Mouse Model of Timothy Syndrome, a Rare Genetic Disorder Associated with Autism Spectrum Disorders

Rendall, A. R., Ford, A., Perrino, P. A., & FITCH, R. H. (2017) · Advances in Neurodevelopmental Disorders · doi:10.1007/s41252-017-0029-1 · Cited by 12 · see citing works

A Semi-Automated Pipeline for the Segmentation of Rhesus Macaque Hippocampus: Validation across a Wide Age Range

Hunsaker, M. R., & Amaral, D. G. (2014) · PLoS ONE · doi:10.1371/journal.pone.0089456 · Cited by 11 · see citing works

Within-subject test-retest reliability of the atlas-based cortical volume measurement in the rat brain: A voxel-based morphometry study

Jing, B., Liu, B., Li, H., Lei, J., Wang, Z., Yang, Y., Sun, P. Z., Xue, B., Liu, H., & Xu, Q. (2018) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2018.06.022 · Cited by 11 · see citing works

Deficits in Cerebellum-Dependent Learning and Cerebellar Morphology in Male and Female BTBR Autism Model Mice

Kiffmeyer, E. A., Cosgrove, J. A., Siganos, J. K., Bien, H. E., Vipond, J. E., Vogt, K. R., & Kloth, A. D. (2022) · NeuroSci · doi:10.3390/neurosci3040045 · Cited by 10 · see citing works

The number of Purkinje neurons and their topology in the cerebellar vermis of normal and reln haplodeficient mouse

Magliaro, C., Cocito, C., Bagatella, S., Merighi, A., Ahluwalia, A. D., & Lossi, L. (2016) · Annals of Anatomy - Anatomischer Anzeiger · doi:10.1016/j.aanat.2016.02.009 · Cited by 10 · see citing works

A Twin Study of Altered White Matter Heritability in Youth With Autism Spectrum Disorder

Hegarty, J. P., Monterrey, J. C., Tian, Q., Cleveland, S. C., Gong, J., Phillips, J. M., Wolke, O. N., McNab, J. A., Hallmayer, J. F., Reiss, A. L., et al. (2023) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2023.05.030 · Cited by 8 · see citing works

The BTBR T+ Itpr3tf/J mouse strain as a model to study the genetic, immune, and metabolic origins of neurodevelopmental disorders

Viscomi, M., Czyrska, J., Winiarczyk, D., Ziętek, M. M., & Sampino, S. (2024) · Research in Autism · doi:10.1016/j.rasd.2024.102526 · Cited by 8 · see citing works

Integrated analysis of miRNA and mRNA expression profiles in the brains of BTBR mice

Wang, M., He, J., Zhou, Y., Lv, N., Zhao, M., Wei, H., & Li, R. (2020) · International Journal of Developmental Neuroscience · doi:10.1002/jdn.10019 · Cited by 8 · see citing works

Neuroimaging Endophenotypes in Animal Models of Autism Spectrum Disorders: Lost or Found in Translation?

Petrinovic, M. M., & Künnecke, B. (2013) · Psychopharmacology · doi:10.1007/s00213-013-3200-z · Cited by 8 · see citing works

Myelin dysfunction in autism spectrum disorder: insights into core symptoms and mechanisms of brain development

Adès, N., & Bouslama‐Oueghlani, L. (2026) · Molecular Psychiatry · doi:10.1038/s41380-026-03490-x · Cited by 7 · see citing works

Translational Magnetic Resonance Imaging in Autism Spectrum Disorder From the Mouse Model to Human

Tsurugizawa, T. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.872036 · Cited by 7 · see citing works

From molecules to models: A holistic review of autism spectrum disorder mechanisms and research tools

Gullapalli, S., Baldado, L., Szobody, M. W., Murambadoro, A. K., Valdez, K. G., Bellamkonda, A., Gonzalez, D., Ghumman, U., Anand, N., Potter–Baker, K. A., et al. (2025) · Neurobiology of Disease · doi:10.1016/j.nbd.2025.107187 · Cited by 5 · see citing works

Progress in magnetic resonance imaging of autism model mice brain

Yang, D., Zhao, Y., Nie, B., An, L., Wan, X., Wang, Y., Wang, W., Cai, G., & Wu, S. (2022) · Wiley Interdisciplinary Reviews Cognitive Science · doi:10.1002/wcs.1616 · Cited by 5 · see citing works

Environmental enrichment reduces restricted repetitive behavior by altering gray matter microstructure

Farmer, A. L., Febo, M., Wilkes, B. J., & Lewis, M. H. (2024) · PLoS ONE · doi:10.1371/journal.pone.0307290 · Cited by 5 · see citing works

Deficit in Social Relationships and Reduced Field of Interest in Mice

Roubertoux, P. L., Carlier, M., & Tordjman, S. (2014) · Neuromethods · doi:10.1007/978-1-4939-2250-5_14 · Cited by 5 · see citing works

Altered responsiveness to pups in virgin female mice of the BTBR strain: Insights from pattern of c-Fos expression in brain regions involved in maternal behavior

Tartaglione, A. M., Vecchioli, S. F., Giorgi, M. C., Cutuli, D., & Calamandrei, G. (2021) · Behavioural Brain Research · doi:10.1016/j.bbr.2021.113365 · Cited by 5 · see citing works

Neural connections and molecular mechanisms underlying motor skill deficits in genetic models of autism spectrum disorders

Duan, J., Zeng, D., Wu, T., Luo, Z., Jingwen, G., Tan, W., & Zeng, Y. (2025) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2025.102759 · Cited by 4 · see citing works

Prenatal stress and fluoxetine exposure in BTBR and B6 mice differentially affects autism-like behaviors in adult male and female offspring

Arzuaga, A. L., Teneqexhi, P., Amodeo, K., Larson, J. R., & Ragozzino, M. E. (2025) · Physiology & Behavior · doi:10.1016/j.physbeh.2025.114891 · Cited by 4 · see citing works

Serotonin Disturbance in Mouse Models of Autism Spectrum Disorders

Tamada, K., & Takumi, T. (2014) · Neuromethods · doi:10.1007/978-1-4939-2250-5_9 · Cited by 4 · see citing works

Neuroimaging Evidence of Major Morpho-Anatomical and Functional Abnormalities in the BTBR T+TF/J Mouse Model of Autism

Dodero, L., Damiano, M., Galbusera, A., Bifone, A., Tsaftsaris, S. A., Scattoni, M. L., & Gozzi, A. (2013) · PLoS ONE · doi:10.1371/journal.pone.0076655 · Cited by 116 · see citing works

Non-diagnostic symptoms in a mouse model of autism in relation to neuroanatomy: the BTBR strain reinvestigated

Faraji, J., Karimi, M., Lawrence, C., Mohajerani, M. H., & Metz, G. A. S. (2018) · Translational Psychiatry · doi:10.1038/s41398-018-0280-x · Cited by 46 · see citing works

Motor and cognitive stereotypies in the BTBR T+tf/J mouse model of autism

Pearson, B. L., Pobbe, R. L. H., Defensor, E. B., Oasay, L., Bolivar, V. J., Blanchard, D. C., & Blanchard, R. J. (2011) · Genes, Brain and Behavior · doi:10.1111/j.1601-183x.2010.00659.x · Cited by 171 · see citing works

Reduced social interaction, behavioural flexibility and BDNF signalling in the BTBR T+tf/J strain, a mouse model of autism

Scattoni, M. L., Martire, A., Cartocci, G., Ferrante, A., & Ricceri, L. (2012) · Behavioural Brain Research · doi:10.1016/j.bbr.2012.12.028 · Cited by 134 · see citing works

Neuroimmunological and genetic influences on autism-like phenotype of BTBR mice

Lawrence, A. D., Heo, Y., & Gao, D. (2010) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2010.07.221