Cited by 127Gut microbiota and healthSpondyloarthritis Studies and TreatmentsPsoriasis: Treatment and Pathogenesis

The DOI matches its Crossref record; 98 of the 98 references it cites were found in a registry or an index.

The gut microbiome in psoriasis and psoriatic arthritis

Myers, Bridget, Brownstone, Nicholas, Reddy, Vidhatha, Chan, Stephanie, Thibodeaux, Quinn, Truong, Alexa, Bhutani, Tina, Chang, Hsin-Wen, Liao, Wilson·2019·Best Practice & Research Clinical Rheumatology

DOI 10.1016/j.berh.2020.101494

Open this paper in CoChat — free account

Abstract

This review summarizes existing research on the gut microbiome composition and function in psoriasis and psoriatic arthritis, exploring potential roles in disease pathogenesis, progression, and management. A strong relationship between skin, joint, and gastrointestinal inflammation exists, as demonstrated by an increased prevalence of psoriasis, psoriatic arthritis, and inflammatory bowel disease co-occurring together; however, the link between them has not been fully elucidated. Studies analyzing the gut microbiome in psoriasis and psoriatic arthritis reveal a unique pattern of dysbiosis. With regard to the gut microbiome's role in psoriasis and psoriatic arthritis pathogenesis, we discuss several theories including intestinal permeability, altered immune homeostasis, and imbalance of short- and medium-chain fatty acid-producing bacteria. We also discuss how the gut microbiome affects patient risk of psoriatic arthritis and other serious comorbidities, and how fecal microbes could be used clinically as therapeutic targets or markers of disease.

Integrity signals

Registry

Crossref · 10.1016/j.berh.2020.101494

Cites

98 of 98 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

A metagenome-wide association study of gut microbiota in type 2 diabetes
Qin, J., Li, Y., Cai, Z., Li, S., Zhu, J., Zhang, F., Liang, S., Zhang, W., Guan, Y., Shen, D., et al. (2012) · Nature · doi:10.1038/nature11450 · Cited by 6,762
Metabolic Endotoxemia Initiates Obesity and Insulin Resistance
Cani, P. D., Amar, J., Iglesias, M. A., Poggi, M., Knauf, C., Bastelica, D., Neyrinck, A. M., Fava, F., Tuohy, K. M., Chabo, C., et al. (2007) · Diabetes · doi:10.2337/db06-1491 · Cited by 6,638
Obesity alters gut microbial ecology
Ley, R. E., Bäckhed, F., Turnbaugh, P., Lozupone, C. A., Knight, R. D., & Gordon, J. I. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0504978102 · Cited by 6,176
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease
Wang, Z., Klipfell, E., Bennett, B. J., Koeth, R., Levison, B. S., DuGar, B., Feldstein, A. E., Britt, E. B., Fu, X., Chung, Y.-M., et al. (2011) · Nature · doi:10.1038/nature09922 · Cited by 5,597
The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic T reg Cell Homeostasis
Smith, P. M., Howitt, M. R., Panikov, N., Michaud, M., Gallini, C. A., Bohlooly-Y, M., Glickman, J. N., & Garrett, W. S. (2013) · Science · doi:10.1126/science.1241165 · Cited by 5,413
Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis
Koeth, R. A., Wang, Z., Levison, B. S., Buffa, J. A., Org, E., Sheehy, B. T., Britt, E. B., Fu, X., Wu, Y., Li, L., et al. (2013) · Nature Medicine · doi:10.1038/nm.3145 · Cited by 4,386
What is the Healthy Gut Microbiota Composition? A Changing Ecosystem across Age, Environment, Diet, and Diseases
Rinninella, E., Raoul, P., Cintoni, M., Franceschi, F., Miggiano, G. A. D., Gasbarrini, A., & Mele, M. C. (2019) · Microorganisms · doi:10.3390/microorganisms7010014 · Cited by 3,462
Influence of diet on the gut microbiome and implications for human health
Singh, R. K., Chang, H.-W., Yan, D., Lee, K. M., Ucmak, D., Wong, K., Abrouk, M., Farahnik, B., Nakamura, M., Zhu, T. H., et al. (2017) · Journal of Translational Medicine · doi:10.1186/s12967-017-1175-y · Cited by 2,599
Self-citation
Gut–brain axis: How the microbiome influences anxiety and depression
Foster, J. A., & McVey Neufeld, K.-A. (2013) · Trends in Neurosciences · doi:10.1016/j.tins.2013.01.005 · Cited by 2,460
Butyrate improves insulin sensitivity and increases energy expenditure in mice
Gao, Z., Yin, J., Zhang, J., Ward, R. E., Martin, R. J., Lefevre, M., Cefalu, W. T., & Ye, J. (2009) · Diabetes · doi:10.2337/db08-1637 · Cited by 2,204
Mediterranean alpha-linolenic acid-rich diet in secondary prevention of coronary heart disease
de Lorgeril, M., Renaud, S., Salen, P., Monjaud, I., Mamelle, N., Martin, J. L., Guidollet, J., Touboul, P., & Delaye, J. (1994) · The Lancet · doi:10.1016/s0140-6736(94)92580-1 · Cited by 2,122
Akkermansia muciniphila and improved metabolic health during a dietary intervention in obesity: relationship with gut microbiome richness and ecology
Dao, M. C., Everard, A., Aron-Wisnewsky, J., Sokolovska, N., Prifti, E., Verger, E. O., Kayser, B. D., Levenez, F., Chilloux, J., Hoyles, L., et al. (2016) · Gut · doi:10.1136/gutjnl-2014-308778 · Cited by 1,931
A decrease of the butyrate-producing species Roseburia hominis and Faecalibacterium prausnitzii defines dysbiosis in patients with ulcerative colitis
Machiels, K., Joossens, M., Sabino, J., De Preter, V., Arijs, I., Eeckhaut, V., Ballet, V., Claes, K., Van Immerseel, F., Verbeke, K., et al. (2014) · Gut · doi:10.1136/gutjnl-2013-304833 · Cited by 1,904
The microbiota in adaptive immune homeostasis and disease
Honda, K., & Littman, D. R. (2016) · Nature · doi:10.1038/nature18848 · Cited by 1,846
Intestinal permeability – a new target for disease prevention and therapy
Bischoff, S. C., Barbara, G., Buurman, W., Ockhuizen, T., Schulzke, J.-D., Serino, M., Tilg, H., Watson, A., & Wells, J. M. (2014) · BMC Gastroenterology · doi:10.1186/s12876-014-0189-7 · Cited by 1,755
Regulation of inflammation by short chain fatty acids
Vinolo, M. A. R., Rodrigues, H. G., Nachbar, R. T., & Curi, R. (2011) · Nutrients · doi:10.3390/nu3100858 · Cited by 1,724
Psoriatic arthritis: epidemiology, clinical features, course, and outcome
Gladman, D. D., Antoni, C., Mease, P. J., Clegg, D. O., & Nash, P. T. (2005) · Annals of the Rheumatic Diseases · doi:10.1136/ard.2004.032482 · Cited by 1,538
Psoriatic Arthritis
Ritchlin, C. T., Colbert, R. A., & Gladman, D. D. (2017) · New England Journal of Medicine · doi:10.1056/nejmra1505557 · Cited by 1,505
Mucolytic Bacteria With Increased Prevalence in IBD Mucosa Augment In Vitro Utilization of Mucin by Other Bacteria
Png, C. W., Lindén, S. K., Gilshenan, K. S., Zoetendal, E. G., McSweeney, C. S., Sly, L. I., McGuckin, M. A., & Florin, T. H. J. (2010) · American Journal of Gastroenterology · doi:10.1038/ajg.2010.281 · Cited by 1,364
Acetate mediates a microbiome–brain–β-cell axis to promote metabolic syndrome
Perry, R. J., Peng, L., Barry, N. A., Cline, G. W., Zhang, D., Cardone, R. L., Petersen, K. F., Kibbey, R. G., Goodman, A. L., & Shulman, G. I. (2016) · Nature · doi:10.1038/nature18309 · Cited by 1,299
Defining the human microbiome
Ursell, L. K., Metcalf, J. L., Parfrey, L. W., & Knight, R. (2012) · Nutrition Reviews · doi:10.1111/j.1753-4887.2012.00493.x · Cited by 1,255
Psoriasis: epidemiology, clinical features, and quality of life
Langley, R. G. B., Krueger, G. G., & Griffiths, C. E. M. (2005) · Annals of the Rheumatic Diseases · doi:10.1136/ard.2004.033217 · Cited by 1,118
Akkermansia muciniphila and its role in regulating host functions
Derrien, M., Belzer, C., & de Vos, W. M. (2017) · Microbial Pathogenesis · doi:10.1016/j.micpath.2016.02.005 · Cited by 1,044
Dietary fatty acids directly impact central nervous system autoimmunity via the small intestine
Haghikia, A., Jörg, S., Duscha, A., Berg, J., Manzel, A., Waschbisch, A., Hammer, A., Lee, D.-H., May, C., Wilck, N., et al. (2015) · Immunity · doi:10.1016/j.immuni.2015.09.007 · Cited by 927
Decreased Bacterial Diversity Characterizes the Altered Gut Microbiota in Patients With Psoriatic Arthritis, Resembling Dysbiosis in Inflammatory Bowel Disease
Scher, J. U., Úbeda, C., Artacho, A., Attur, M. G., Isaac, S., Reddy, S. M., Marmon, S., Neimann, A. L., Brusca, S. B., Patel, T., et al. (2014) · Arthritis & Rheumatology · doi:10.1002/art.38892 · Cited by 844
Roles for Intestinal Bacteria, Viruses, and Fungi in Pathogenesis of Inflammatory Bowel Diseases and Therapeutic Approaches
Sartor, R. B., & Wu, G. D. (2017) · Gastroenterology · doi:10.1053/j.gastro.2016.10.012 · Cited by 808
Intestinal Integrity and Akkermansia muciniphila , a Mucin-Degrading Member of the Intestinal Microbiota Present in Infants, Adults, and the Elderly
Collado, M. C., Derrien, M., Isolauri, E., de Vos, W. M., & Salminen, S. (2007) · Applied and Environmental Microbiology · doi:10.1128/aem.01477-07 · Cited by 706
Diagnostic delay of more than 6 months contributes to poor radiographic and functional outcome in psoriatic arthritis
Haroon, M., Gallagher, P., & FitzGerald, O. (2014) · Annals of the Rheumatic Diseases · doi:10.1136/annrheumdis-2013-204858 · Cited by 627
The Gut Microbiome Profile in Obesity: A Systematic Review
Castaner, O., Goday, A., Park, Y.-M., Lee, S.-H., Magkos, F., Shiow, S.-A. T. E., & Schröder, H. (2018) · International Journal of Endocrinology · doi:10.1155/2018/4095789 · Cited by 570
Faecalibacterium prausnitzii produces butyrate to maintain Th17/Treg balance and to ameliorate colorectal colitis by inhibiting histone deacetylase 1
Zhou, L., Zhang, M., Wang, Y., Dorfman, R. G., Liu, H., Yu, T., Chen, X., Tang, D., Xu, L., Yin, Y., et al. (2018) · Inflammatory Bowel Diseases · doi:10.1093/ibd/izy182 · Cited by 525
Probiotics Ameliorate Recurrent Th1-Mediated Murine Colitis by Inducing IL-10 and IL-10-Dependent TGF-β-Bearing Regulatory Cells
Giacinto, C. D., Marinaro, M., Sanchez, M., Strober, W., & Boirivant, M. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.174.6.3237 · Cited by 522
Cause-specific mortality in patients with severe psoriasis: a population-based cohort study in the U.K.
Abuabara, K., Azfar, R. S., Shin, D. B., Neimann, A. L., Troxel, A. B., & Gelfand, J. M. (2010) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2010.09941.x · Cited by 485
The gut microbiota in human energy homeostasis and obesity
Rosenbaum, M., Knight, R., & Leibel, R. L. (2015) · Trends in Endocrinology & Metabolism · doi:10.1016/j.tem.2015.07.002 · Cited by 450
Bifidobacterium infantis35624 modulates host inflammatory processes beyond the gut
Groeger, D., O’Mahony, L., Murphy, E. F., Bourke, J. F., Dinan, T. G., Kiely, B., Shanahan, F., & Quigley, E. M. M. (2013) · Gut Microbes · doi:10.4161/gmic.25487 · Cited by 448
Microbial butyrate and its role for barrier function in the gastrointestinal tract
Plöger, S., Stumpff, F., Penner, G. B., Schulzke, J., Gäbel, G., Märtens, H., Shen, Z., Günzel, D., & Aschenbach, J. R. (2012) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2012.06553.x · Cited by 445
Cultured Representatives of Two Major Phylogroups of Human Colonic Faecalibacterium prausnitzii Can Utilize Pectin, Uronic Acids, and Host-Derived Substrates for Growth
Lopez-Siles, M., Khan, T. M., Duncan, S. H., Harmsen, H. J. M., Garcia-Gil, L. J., & Flint, H. J. (2012) · Applied and Environmental Microbiology · doi:10.1128/aem.06858-11 · Cited by 433
Medium Chain Fatty Acids Are Selective Peroxisome Proliferator Activated Receptor (PPAR) γ Activators and Pan-PPAR Partial Agonists
Liberato, M. V., Nascimento, A. S., Ayers, S. D., Lin, J. Z., Čvoro, A., Silveira, R. L., Martínez, L., Souza, P. C. T., Saidemberg, D. M., Deng, T., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0036297 · Cited by 421
Faecalibacterium prausnitzii subspecies-level dysbiosis in the human gut microbiome underlying atopic dermatitis
Song, H., Yoo, Y., Hwang, J., Na, Y.-C., & Kim, H. S. (2016) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2015.08.021 · Cited by 416
An experimental study of a Mediterranean diet intervention for patients with rheumatoid arthritis
Sköldstam, L., Hagfors, L., & Johansson, G. (2003) · Annals of the Rheumatic Diseases · doi:10.1136/ard.62.3.208 · Cited by 409
Preventing psoriatic arthritis: focusing on patients with psoriasis at increased risk of transition
Scher, J. U., Ogdie, A., Merola, J. F., & Ritchlin, C. T. (2019) · Nature Reviews Rheumatology · doi:10.1038/s41584-019-0175-0 · Cited by 409
Trimethylamine‐ N ‐oxide (TMAO) response to animal source foods varies among healthy young men and is influenced by their gut microbiota composition: A randomized controlled trial
Cho, C. E., Taesuwan, S., Malysheva, O. V., Bender, E., Tulchinsky, N. F., Yan, J., Sutter, J. L., & Caudill, M. A. (2017) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201600324 · Cited by 405
Psoriasis: classical and emerging comorbidities
de Oliveira, M. D. F. S. P., Rocha, B. D. O., & Duarte, G. V. (2015) · Anais Brasileiros de Dermatologia · doi:10.1590/abd1806-4841.20153038 · Cited by 369
Strain-Specific Anti-inflammatory Properties of Two Akkermansia muciniphila Strains on Chronic Colitis in Mice
Zhai, R., Xue, X., Zhang, L., Yang, X., Zhao, L., & Zhang, C. (2019) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2019.00239 · Cited by 368
Psoriasis and the metabolic syndrome
Gisondi, P., Fostini, A. C., Fossà, I., Girolomoni, G., & Targher, G. (2017) · Clinics in Dermatology · doi:10.1016/j.clindermatol.2017.09.005 · Cited by 353
Decreased abundance of Faecalibacterium prausnitzii in the gut microbiota of Crohn's disease
Fujimoto, T., Imaeda, H., Takahashi, K., Kasumi, E., Bamba, S., Fujiyama, Y., & Andoh, A. (2013) · Journal of Gastroenterology and Hepatology · doi:10.1111/jgh.12073 · Cited by 304
The Microbiome and Risk for Obesity and Diabetes
Komaroff, A. L. (2016) · JAMA · doi:10.1001/jama.2016.20099 · Cited by 296
Psoriasis and Obesity
Jensen, P., & Skov, L. (2016) · Dermatology · doi:10.1159/000455840 · Cited by 281
Is the prevalence of psoriasis increasing? A 30-year follow-up of a population-based cohort
Danielsen, K., Olsen, A. O., Wilsgaard, T., & Furberg, A. (2013) · British Journal of Dermatology · doi:10.1111/bjd.12230 · Cited by 277
Alterations in the Intestinal Microbiome (Dysbiosis) as a Predictor of Relapse After Infliximab Withdrawal in Crohnʼs Disease
Rajca, S., Grondin, V., Louis, E. J., Vernier-Massouille, G., Grimaud, J., Bouhnik, Y., Laharie, D., Dupas, J., Pillant, H., Picon, L., et al. (2014) · Inflammatory Bowel Diseases · doi:10.1097/mib.0000000000000036 · Cited by 247
The role of intestinal microbiota in cardiovascular disease
Jin, M., Qian, Z., Yin, J., Xu, W., & Zhou, X. (2019) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.14195 · Cited by 246
Faecal metabolite profiling identifies medium-chain fatty acids as discriminating compounds in IBD
Preter, V. D., Machiels, K., Joossens, M., Arijs, I., Matthys, C., Vermeire, S., Rutgeerts, P. J., & Verbeke, K. (2014) · Gut · doi:10.1136/gutjnl-2013-306423 · Cited by 238
Gut microbiota dysbiosis in a cohort of patients with psoriasis
Hidalgo‐Cantabrana, C., Gómez, J., Delgado, S., Requena‐López, S., Queiro‐Silva, R., Margolles, A., Coto, E., Sánchez, B., & Coto‐Segura, P. (2019) · British Journal of Dermatology · doi:10.1111/bjd.17931 · Cited by 236
Effect of Weight Loss on the Severity of Psoriasis
Jensen, P., Zachariae, C. O. C., Christensen, R., Geiker, N. R. W., Schaadt, B. K., Stender, S., Hansen, P. R., Astrup, A. V., & Skov, L. (2013) · JAMA Dermatology · doi:10.1001/jamadermatol.2013.722 · Cited by 228
Butyrate inhibits interleukin-17 and generates Tregs to ameliorate colorectal colitis in rats
Zhang, M., Zhou, Q., Dorfman, R. G., Huang, X., Fan, T., Zhang, H., Zhang, J., & Yu, C. (2016) · BMC Gastroenterology · doi:10.1186/s12876-016-0500-x · Cited by 218
Gut microbial composition in patients with psoriasis
Codoñer, F. M., Ramírez-Boscá, A., Climent, E., Carrión-Gutiérrez, M. A., Guerrero, M., Pérez-Orquín, J. M., de la Parte, J. H., Genovés, S., Ramón, D., Navarro‐López, V., et al. (2018) · Scientific Reports · doi:10.1038/s41598-018-22125-y · Cited by 213
Psoriasis patients with antibodies to gliadin can be improved by a gluten-free diet
MICHAELSSON, G., Gerdén, B., Hagforsen, E., Nilsson, B., Pihl-Lundin, I., Kraaz, W., Hjelmquist, G., & Lööf, L. (2000) · British Journal of Dermatology · doi:10.1046/j.1365-2133.2000.03240.x · Cited by 209
Diet and physical exercise in psoriasis: a randomized controlled trial
Naldi, L., Conti, A., Cazzaniga, S., Patrizi, A., Pazzaglia, M., Lanzoni, A., Veneziano, L. S. N., Pellacani, G., & the Psoriasis Emilia Romagna Study Group (2013) · British Journal of Dermatology · doi:10.1111/bjd.12735 · Cited by 208
Similar Depletion of ProtectiveFaecalibacterium prausnitziiin Psoriasis and Inflammatory Bowel Disease, but not in Hidradenitis Suppurativa
Eppinga, H., Weiland, C. J. S., Thio, H. B., van der Woude, C. J., Nijsten, T. E. C., Peppelenbosch, M. P., & Konstantinov, S. R. (2016) · Journal of Crohn s and Colitis · doi:10.1093/ecco-jcc/jjw070 · Cited by 199
The Akkermansia muciniphila is a gut microbiota signature in psoriasis
Tan, L., Zhao, S., Zhu, W., Wu, L., Li, J., Shen, M., Li, L., Chen, X., & Peng, C. (2017) · Experimental Dermatology · doi:10.1111/exd.13463 · Cited by 191
Dietary Recommendations for Adults With Psoriasis or Psoriatic Arthritis From the Medical Board of the National Psoriasis Foundation
Ford, A. R., Siegel, M. P., Bagel, J., Cordoro, K. M., Garg, A., Gottlieb, A. B., Green, L. J., Gudjonsson, J. E., Koo, J. Y. M., Lebwohl, M., et al. (2018) · JAMA Dermatology · doi:10.1001/jamadermatol.2018.1412 · Cited by 180
The role of the skin microbiome in atopic dermatitis
Nakatsuji, T., & Gallo, R. L. (2018) · Annals of Allergy Asthma & Immunology · doi:10.1016/j.anai.2018.12.003 · Cited by 167
Diet, the intestinal microbiota, and immune health in aging
Clements, S. J., & Carding, S. R. (2016) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2016.1211086 · Cited by 163
Psoriatic patients have a distinct structural and functional fecal microbiota compared with controls
Shapiro, J., Cohen, N. A., Shalev, V., Uzan-Yulzari, A., Koren, O., & Maharshak, N. (2019) · The Journal of Dermatology · doi:10.1111/1346-8138.14933 · Cited by 163
High-Fat Diet Exacerbates Early Psoriatic Skin Inflammation Independent of Obesity: Saturated Fatty Acids as Key Players
Herbert, D., Franz, S., Popkova, Y., Anderegg, U., Schiller, J., Schwede, K., Lorz, A., Simon, J. C., & Saalbach, A. (2018) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2018.03.1522 · Cited by 158
The role of the skin and gut microbiome in psoriatic disease
Yan, D., Issa, N., Afifi, L., Jeon, C., Chang, H.-W., & Liao, W. (2017) · Current Dermatology Reports · doi:10.1007/s13671-017-0178-5 · Cited by 135
Self-citation
Diet and psoriasis, part II: Celiac disease and role of a gluten-free diet
Bhatia, B. K., Millsop, J. W., Debbaneh, M. G., Koo, J. Y. M., Linos, E., & Liao, W. J. (2014) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2014.03.017 · Cited by 123
Intestinal microbiota profiling and predicted metabolic dysregulation in psoriasis patients
Chen, Y., Ho, H. J., Tseng, C., Lai, Z.-L., Shieh, J., & Wu, C. (2018) · Experimental Dermatology · doi:10.1111/exd.13786 · Cited by 123
Efficacy and Safety of Oral Administration of a Mixture of Probiotic Strains in Patients with Psoriasis: a Randomized Clinical Trial
Navarro‐López, V., Martínez‐Andrés, A., Ramírez-Boscá, A., Ruzafa-Costas, B., Núñez-Delegido, E., Carrión-Gutiérrez, M. A., Prieto‐Merino, D., Codoñer-Cortés, F. M., Ramón, D., Genovés, S., et al. (2019) · Acta Dermato Venereologica · doi:10.2340/00015555-3305 · Cited by 120
Interval between onset of psoriasis and psoriatic arthritis comparing the UK Clinical Practice Research Datalink with a hospital-based cohort
Tillett, W. L., Charlton, R. A., Nightingale, A. L., Snowball, J. M., Green, A. C. A., Smith, C. H., Shaddick, G., & McHugh, N. J. (2017) · Lara D. Veeken · doi:10.1093/rheumatology/kex323 · Cited by 116
Conjugated linoleic acid modulates immune responses in patients with mild to moderately active Crohn's disease
Bassaganya-Riera, J., Hontecillas, R., Horne, W. T., Sandridge, M., Herfarth, H. H., Bloomfeld, R. S., & Isaacs, K. L. (2012) · Clinical Nutrition · doi:10.1016/j.clnu.2012.03.002 · Cited by 107
Fecal Microbial Transplantation for Diseases Beyond Recurrent Clostridium Difficile Infection
D’Haens, G., & Jobin, C. (2019) · Gastroenterology · doi:10.1053/j.gastro.2019.04.053 · Cited by 104
Normal Skin Microbiota is Altered in Pre-clinical Hidradenitis Suppurativa
Ring, H. C., Bay, L., Kallenbach, K., Miller, I. M., Prens, E. P., Saunte, D. M. L., Bjarnsholt, T., & Jemec, G. B. E. (2016) · Acta Dermato Venereologica · doi:10.2340/00015555-2503 · Cited by 103
Course of gut inflammation in spondylarthropathies and therapeutic consequences
Mielants, H., VEYS, E. M., Cuvelier, C. A., & Vos, M. D. (1996) · Baillière s Clinical Rheumatology · doi:10.1016/s0950-3579(96)80010-0 · Cited by 101
Diet and psoriasis, part III: Role of nutritional supplements
Millsop, J. W., Bhatia, B. K., Debbaneh, M. G., Koo, J. Y. M., & Liao, W. J. (2014) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2014.03.016 · Cited by 100
Identification of Bacterial DNA in the Peripheral Blood of Patients With Active Psoriasis
Ramírez-Boscá, A., Navarro‐López, V., Martínez‐Andrés, A., Such, J. M., Francés, R., de la Parte, J. H., & Asín‐Llorca, M. (2015) · JAMA Dermatology · doi:10.1001/jamadermatol.2014.5585 · Cited by 99
Energy-restricted, n-3 polyunsaturated fatty acids-rich diet improves the clinical response to immuno-modulating drugs in obese patients with plaque-type psoriasis: a randomized control clinical trial
Guida, B., Napoleone, A., Trio, R., Nastasi, A., Balato, N., Laccetti, R., & Cataldi, M. (2013) · Clinical Nutrition · doi:10.1016/j.clnu.2013.09.010 · Cited by 96
The Microbiome and Psoriatic Arthritis
Eppinga, H., Konstantinov, S. R., Peppelenbosch, M. P., & Thio, H. B. (2014) · Current Rheumatology Reports · doi:10.1007/s11926-013-0407-2 · Cited by 86
Heterogeneity of Response to Biologic Treatment: Perspective for Psoriasis
Edson‐Heredia, E., Sterling, K. L., Alatorre, C., Carter, G. C., Paczkowski, R., Zarotsky, V., & Maeda‐Chubachi, T. (2013) · Journal of Investigative Dermatology · doi:10.1038/jid.2013.326 · Cited by 85
Short, but Smart: SCFAs Train T Cells in the Gut to Fight Autoimmunity in the Brain
Bhutia, Y. D., & Ganapathy, V. (2015) · Immunity · doi:10.1016/j.immuni.2015.09.014 · Cited by 79
Gut Microbiome in Psoriasis is Perturbed Differently During Secukinumab and Ustekinumab Therapy and Associated with Response to Treatment
Yeh, N.-L., Hsu, C.-Y., Tsai, T., & Chiu, H. (2019) · Clinical Drug Investigation · doi:10.1007/s40261-019-00849-7 · Cited by 79
Adverse effects of gluten ingestion and advantages of gluten withdrawal in nonceliac autoimmune disease
Lerner, A., Shoenfeld, Y., & Matthias, T. (2017) · Nutrition Reviews · doi:10.1093/nutrit/nux054 · Cited by 78
Biomarkers of Inflammation in Obesity-Psoriatic Patients
Rodríguez‐Cerdeira, C., Cordeiro-Rodríguez, M., Carnero-Gregorio, M., López-Bárcenas, A., Martínez-Herrera, E. O., Fabbrocini, G., Sinani, A., Arenas, R., & González-Cespón, J. L. (2019) · Mediators of Inflammation · doi:10.1155/2019/7353420 · Cited by 75
Psoriasis and inflammatory bowel disease: links and risks
Bassukas, I. D., Gaitanis, G., Katsanos, K., Christodoulou, D. K., Tsianos, E. V., & Vlachos, C. (2016) · Psoriasis Targets and Therapy · doi:10.2147/ptt.s85194 · Cited by 72
Early Psoriatic Arthritis
Gladman, D. D. (2012) · Rheumatic Disease Clinics of North America · doi:10.1016/j.rdc.2012.05.005 · Cited by 69
Efficacy and safety of faecal microbiota transplantation in patients with psoriatic arthritis: protocol for a 6-month, double-blind, randomised, placebo-controlled trial
Kragsnæs, M. S., Kjeldsen, J., Horn, H. C., Munk, H. L., Pedersen, F. M., Holt, H. M., Stengaard‐Pedersen, K., Holm, D. K., Glerup, H., Andersen, V. C., et al. (2018) · BMJ Open · doi:10.1136/bmjopen-2017-019231 · Cited by 67
Rapid Regression of Psoriasis in a Coeliac Patient after Gluten-Free Diet
Addolorato, G., Parente, A., de Lorenzi, G., Paola, M. E. D. D., Abenavoli, L., Leggio, L., Capristo, E., SIMONE, C. D., Rotoli, M., Rapaccini, G. L., et al. (2003) · Digestion · doi:10.1159/000073220 · Cited by 62
How lifestyle factors and their associated pathogenetic mechanisms impact psoriasis
Madden, S. K., Flanagan, K. L., & Jones, G. (2019) · Clinical Nutrition · doi:10.1016/j.clnu.2019.05.006 · Cited by 59
Gut bacterial microbiota in psoriasis: A case control study
Doaa, M., Dalia, M., & Ahmed, F. S. (2016) · African Journal of Microbiology Research · doi:10.5897/ajmr2016.8046 · Cited by 56
A patient with osteomalacia as single presenting symptom of gluten‐sensitive enteropathy
de BOER, L. W. A., & Tytgat, G. N. J. (1992) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.1992.tb00554.x · Cited by 52
The intestinal microbiome in human disease and how it relates to arthritis and spondyloarthritis
Costello, M., Robinson, P. C., Benham, H., & Brown, M. A. (2015) · Best Practice & Research Clinical Rheumatology · doi:10.1016/j.berh.2015.08.001 · Cited by 44
Serum homocysteine, asymmetric dimethyl arginine (ADMA) and other arginine–NO pathway metabolite levels in patients with psoriasis
Bilgiç, Ö., Altinyazar, H. C., Baran, H., & Ünlü, A. (2015) · Archives of Dermatological Research · doi:10.1007/s00403-015-1553-3 · Cited by 41
Antibiotic Exposure, Infection, and the Development of Pediatric Psoriasis
Horton, D. B., Scott, F. I., Haynes, K., Putt, M. E., Rosé, C. D., Lewis, J. D., & Strom, B. L. (2015) · JAMA Dermatology · doi:10.1001/jamadermatol.2015.3650 · Cited by 36
Evaluation of subclinical gut inflammation using faecal calprotectin levels and colonic mucosal biopsy in patients with psoriasis and psoriatic arthritis
Adarsh, M. B., Dogra, S., Vaiphei, K., Vaishnavi, C. V., Sinha, S. K., & Sharma, A. (2019) · British Journal of Dermatology · doi:10.1111/bjd.17745 · Cited by 36
Efficacy of erythromycin for psoriasis vulgaris
Polat, M., Lenk, N., Yalçın, B., Gür, G., Tamer, E., Artüz, F., & Allı, N. (2007) · Clinical and Experimental Dermatology · doi:10.1111/j.1365-2230.2007.02370.x · Cited by 33
Psoriatic arthritis: tissue-directed inflammation?
Cafaro, G., & McInnes, I. B. (2018) · Clinical Rheumatology · doi:10.1007/s10067-018-4012-7 · Cited by 32
A review of antibiotics and psoriasis: induction, exacerbation, and amelioration
Tsai, Y., & Tsai, T. (2019) · Expert Review of Clinical Pharmacology · doi:10.1080/17512433.2019.1665027 · Cited by 27
Frequency of Homocysteinemia in Young Ischemic Stroke Patients and Its Relationship with the Early Outcome of a Stroke
Niazi, F., Aslam, A., Khattak, S., & Waheed, S. (2019) · Cureus · doi:10.7759/cureus.5625 · Cited by 20
Osteomalacia associated with cutaneous psoriasis as the presenting feature of coeliac disease: a case report.
Frikha, F., Snoussi, M., & Bahloul, Z. (2012) · PubMed · doi:10.11604/pamj.2012.11.58.1613 · Cited by 10

Research works printed but not linked: 1

Kim, 2010, Drug-provoked psoriasis: is it drug induced or drug aggravated?, J Clin Aesthetic Dermatol, 3, 32

Sorted by citations

Probiotics Regulate Gut Microbiota: An Effective Method to Improve Immunity
Wang, X., Zhang, P., & Zhang, X. (2021) · Molecules · doi:10.3390/molecules26196076 · Cited by 529
Impact of gut microbiome on skin health: gut-skin axis observed through the lenses of therapeutics and skin diseases
Mahmud, M. R., Akter, S., Tamanna, S. K., Mazumder, L., Esti, I. Z., Banerjee, S., Akter, S., Hasan, M. R., Acharjee, M., Hossain, M. S., et al. (2022) · Gut Microbes · doi:10.1080/19490976.2022.2096995 · Cited by 513
“Clostridium citroniae, Collinsella aerofaciens, Dorea formicigenerans, Parabacteroides distasonis, Prevotella copri, and Ruminococcus gnavus.(149,151) Technological advancements have opened up new possibilities for the selection and manufacture of monoclonal antibodies that target specific diseases.”
Background
Skin Barrier Dysregulation in Psoriasis
Orsmond, A., Bereza-Malcolm, L., Lynch, T., MARCH, L. M., & Xue, M. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms221910841 · Cited by 250
Psoriasis and Gut Microbiome—Current State of Art
Polak, K., Bergler-Czop, B. S., Szczepanek, M., Wojciechowska, K., Frątczak, A., & Kiss, N. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22094529 · Cited by 133
“This may result in the restoration of the correct bacterial microbiota composition [33,68,81,82].”
Background
Exploring the Links between Obesity and Psoriasis: A Comprehensive Review
Barros, G., Durán, P., Vera, I., & Bermúdez, V. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23147499 · Cited by 142
“These pathological changes in microbiota support the chronic inflammatory state hypothesis [29] based on lipoteichoic acid and lipopolysaccharides released into the bloodstream [39].”
BackgroundInfluential

See all 127

Authors: Myers, B., Brownstone, N., Reddy, V., Chan, S., Thibodeaux, Q., Truong, A., Bhutani, T., Chang, H.-W., & Liao, W.
Affiliations: University of California, San Francisco (US)
University of California, Berkeley (US)
Corresponding author: Liao, Wilson
ORCID: Myers, Bridget
Brownstone, Nicholas
Reddy, Vidhatha
Chan, Stephanie
Thibodeaux, Quinn
Truong, Alexa
Bhutani, Tina
Chang, Hsin-Wen
Liao, Wilson
Venue: Best Practice & Research Clinical Rheumatology
Publisher: Elsevier BV
Published: 2019-12
Volume: 33
Issue: 6
Pages: 101494
ISSN: 1521-6942 (ISSN-L)
DOI: 10.1016/j.berh.2020.101494
OpenAlex: W3023269883
Cited by: 127
References: 98
Citations by year: 2026: 10 · 2025: 11 · 2024: 31 · 2023: 26 · 2022: 23 · 2021: 24 · 2020: 2
FWCI: 1.08
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
Locations: Best Practice & Research Clinical Rheumatology (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
Health Sciences › Medicine › Rheumatology › Spondyloarthritis Studies and Treatments
Life Sciences › Immunology and Microbiology › Immunology › Psoriasis: Treatment and Pathogenesis
Keywords: gut microbiota, psoriasis, psoriatic arthritis, dysbiosis, intestinal permeability, immune homeostasis, short-chain fatty acids, medium-chain fatty acids, inflammatory bowel disease, comorbidities, pathogenesis, fecal microbiota transplantation, biomarkers, therapeutic target
MeSH terms: Gastrointestinal Microbiome, Humans, Psoriasis, Arthritis, Psoriatic, Microbiota, Dysbiosis

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

The gut microbiome in psoriasis and psoriatic arthritis

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks