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Identification of cuproptosis-related genes in Alzheimer’s disease based on bioinformatic analysis

Ma, M., Zhao, J., Liu, L., & Wu, C.-Y. (2024) · European journal of medical research · doi:10.1186/s40001-024-02093-y · Cited by 13 · see citing works

Biofilm-modified Prussian blue improves memory function in late-stage Alzheimer’s disease mice with triple therapy

Li, L., Zhang, J., Zhang, Y., Zhao, R., Yang, F., Yan, Y., Wang, Q., & Xie, M. (2024) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2024.125112 · Cited by 13 · see citing works

Visualizing Endoplasmic Reticulum Stress and Autophagy in Alzheimer’s Model Cells by a Peroxynitrite-Responsive AIEgen Fluorescent Probe

Huang, L., Ma, L., Zhu, Q., Wang, H., She, G., Shi, W., & Mu, L. (2025) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.4c00770 · Cited by 13 · see citing works

Postsynaptic Protein Shank3a Deficiency Synergizes with Alzheimer's Disease Neuropathology to Impair Cognitive Performance in the 3xTg-AD Murine Model

Landry, O., François, A., Mi-mba, M.-F. O. M., Traversy, M.-T., Tremblay, C., Émond, V., Bennett, D. A., Gylys, K. H., Buxbaum, J. D., & Calon, F. (2023) · Journal of Neuroscience · doi:10.1523/jneurosci.1945-22.2023 · Cited by 13 · see citing works

LPS mediates cuproptosis and inflammation in THP-1 macrophages through HKDC1

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Synthesis and evaluation of butylphthalide-scutellarein hybrids as multifunctional agents for the treatment of Alzheimer's disease

Yu, G., Shi, Y., Cong, S., Wu, C., Liu, J., Zhang, Y., Liu, H., Liu, X., Deng, H., Tan, Z., et al. (2023) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2023.116099 · Cited by 12 · see citing works

Fasting, a Potential Intervention in Alzheimer's Disease

Zeng, Z., Zhang, H., Wang, X., Shen, J., & Chen, D. (2024) · Journal of Integrative Neuroscience · doi:10.31083/j.jin2303050 · Cited by 12 · see citing works

Deciphering Copper Homeostasis and Cuproptosis: Biological Mechanisms, Disease Connections, and Cutting-Edge Copper-Based Nanomedicine

Zhang, S.-X., Li, L., Wang, L.-J., Chen, N.-N., Leng, F., Xu, H.-Z., & Li, T. (2026) · Molecular Pharmaceutics · doi:10.1021/acs.molpharmaceut.5c01708 · Cited by 11 · see citing works

Recent advances in antioxidant carbon dots for biomedical applications

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Characterization of Uranyl (UO 2 2+ ) Ion Binding to Amyloid Beta (Aβ) Peptides: Effects on Aβ Structure and Aggregation

Berntsson, E., Vosough, F., Noormägi, A., Padari, K., Asplund, F., Gielnik, M. B., Paul, S., Jarvet, J., Tõugu, V., Roos, P. M., et al. (2023) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.3c00130 · Cited by 10 · see citing works

Label-Free In Situ Chemical Characterization of Amyloid Plaques in Human Brain Tissues

Everett, J. L., Brooks, J., Tjhin, V. T., Lermyte, F., Hands-Portman, I., Plascencia‐Villa, G., Perry, G. L., Sadler, P. J., O’Connor, P. B., Collingwood, J. F., et al. (2024) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.3c00756 · Cited by 11 · see citing works

Transcellular transmission and molecular heterogeneity of aggregation-prone proteins in neurodegenerative diseases

Lee, E., Park, H., & Kim, S. (2024) · Molecules and Cells · doi:10.1016/j.mocell.2024.100089 · Cited by 11 · see citing works

Rivastigmine structure-based hybrids as potential multi-target anti-Alzheimer’s drug candidates

Leuci, R., Simić, S., Carrieri, A., Chaves, S., Spada, G. L., Brunetti, L., Tortorella, P., Loiodice, F., Laghezza, A., Catto, M., et al. (2024) · Bioorganic Chemistry · doi:10.1016/j.bioorg.2024.107895 · Cited by 11 · see citing works

Discovery of novel theophylline derivatives bearing tetrazole scaffold for the treatment of Alzheimer's disease

Hưng, N. V., Tien, L. Q., Linh, V. N. H., Tran, H., Nguyen, T. K., Pham, D., Hoang, V.-H., Hiền, T. T. T., Nguyen, T. X., Thai, Q. M., et al. (2025) · RSC Advances · doi:10.1039/d5ra00488h · Cited by 11 · see citing works

Advancing Nanomaterial-Based Strategies for Alzheimer’s Disease: A Perspective

Zhou, H., Yin, X., Zhang, G., Yang, Z., & Zhou, R. (2025) · JACS Au · doi:10.1021/jacsau.5c00002 · Cited by 14 · see citing works

Size-Controlled Mesoporous Silica Nanoparticles via Template Nanoarchitectonics from a Deferoxamine Derivative for Enhanced Blood–Brain Barrier Permeability and Neuroprotective Chelation Therapy

Onrubia-Márquez, M., Navas, F., Sánchez‐Carnerero, E. M. M., Martín, A. D., Liturri, A., Miciaccia, M., Sanz, R., Scilimati, A., García‐Muñoz, R. A., Perrone, M. G., et al. (2025) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.5c18528 · Cited by 10 · see citing works

MAD—microbial (origin of) Alzheimer’s disease hypothesis: from infection and the antimicrobial response to disruption of key copper-based systems

Min, J.-H., Sarlus, H., & Harris, R. A. (2024) · Frontiers in Neuroscience · doi:10.3389/fnins.2024.1467333 · Cited by 11 · see citing works

A cocktail of Cu 2+ - and Zn 2+ -peptoid-based chelators can stop ROS formation for Alzheimer's disease therapy

Behar, A. E., & Maayan, G. (2024) · Chemical Science · doi:10.1039/d4sc04313h · Cited by 10 · see citing works

Discovery of novel thiosemicarbazone-acridine targeting butyrylcholinesterase with antioxidant, metal complexing and neuroprotector abilities as potential treatment of Alzheimer's disease: In vitro, in vivo, and in silico studies

Sousa, G. L. S., Nadur, N. F., Ferreira, L. A., Honório, T. D. S., Simon, A., Cabral, L. M., Santos, M. L. M., Andrade, B., de Lima, E. V., Clarke, J. R., et al. (2024) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2024.117030 · Cited by 12 · see citing works

Playing Around the Coumarin Core in the Discovery of Multimodal Compounds Directed at Alzheimer’s-Related Targets: A Recent Literature Overview

Rullo, M., Spada, G. L., Stefanachi, A., Macchia, E., Pisani, L., & Leonetti, F. (2025) · Molecules · doi:10.3390/molecules30040891 · Cited by 10 · see citing works

Mapping the Path to Cryogenic Atom Probe Tomography Analysis of Biomolecules

Woods, E., Schwarz, T. M., Singh, M. P., Zhang, S., Kim, S., El-Zoka, A. A., Gremer, L., Willbold, D., McCarroll, I. E., & Gault, B. (2025) · Microscopy and Microanalysis · doi:10.1093/mam/ozaf032 · Cited by 10 · see citing works

A dual functional fluorescent probe based on naphthalimide for detecting Cu2+ and pH and its applications

Zhang, C., Wang, Y., Li, X., Nie, S., Liu, C., Zhang, Y., Guo, J., & Liu, C. (2023) · Inorganica Chimica Acta · doi:10.1016/j.ica.2023.121544 · Cited by 10 · see citing works

Osmundacetone ameliorates Alzheimer's-like pathologies by inhibiting β-amyloid fibrillation, oxidative damage and neuroinflammation in APP/PS1 transgenic mice

Zhao, L., Ren, H., Su, J., Zhang, Q., He, D., Wu, T.-Y., Zhang, Y.-H., Wang, Z., & Fan, Y. (2024) · Phytomedicine · doi:10.1016/j.phymed.2024.156091 · Cited by 9 · see citing works

Naringin and Naringenin: Potential Multi-Target Agents for Alzheimer’s Disease

Lu, J., Chen, J., Li, S., Pan, G.-J., Ou, Y., Yuan, L.-F., Jiang, J., Zeng, L., & Zhao, J. J. (2024) · Current Medical Science · doi:10.1007/s11596-024-2921-z · Cited by 9 · see citing works

Determination of Potential Lead Compound from Magnolia officinalis for Alzheimer’s Disease through Pharmacokinetic Prediction, Molecular Docking, Dynamic Simulation, and Experimental Validation

Youn, K., & Jun, M. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms251910507 · Cited by 8 · see citing works

Bifunctional Copper Chelators Capable of Reducing Aβ Aggregation and Aβ-Induced Oxidative Stress

Krasnovskaya, O. O., Abramchuk, D., Vaneev, A. N., Gorelkin, P. V., Abakumov, M. A., Timoshenko, R. V., Kuzmichev, I., Chmelyuk, N. S., Vadekhina, V. V., Kuanaeva, R. M., et al. (2024) · ACS Omega · doi:10.1021/acsomega.4c03152 · Cited by 10 · see citing works

Multifunctional porphyrin-substituted phenylalanine–phenylalanine nanoparticles for diagnostic and therapeutic applications in Alzheimer’s disease

Xia, N., Huang, Y., He, C., Li, Y., Yang, S., & Liu, L. (2024) · Bioorganic Chemistry · doi:10.1016/j.bioorg.2024.108065 · Cited by 9 · see citing works

Fatuamide A, a Hybrid PKS/NRPS Metallophore from a Leptolyngbya sp. Marine Cyanobacterium Collected in American Samoa

Alexander, K. L., Naman, C. B., Iwasaki, A., Mangoni, A., Leão, T., Reher, R., Petras, D., Kim, H. W., Ternon, E., Caro‐Diaz, E. J. E., et al. (2025) · Journal of Natural Products · doi:10.1021/acs.jnatprod.4c01051 · Cited by 8 · see citing works

Molecular interactions, structural effects, and binding affinities between silver ions (Ag+) and amyloid beta (Aβ) peptides

Lakela, A. L., Berntsson, E., Vosough, F., Jarvet, J., Paul, S., Barth, A., Gräslund, A., Roos, P. M., & Wärmländer, S. K. T. S. (2025) · Scientific Reports · doi:10.1038/s41598-024-59826-6 · Cited by 9 · see citing works

From copper homeostasis to cuproptosis: a new perspective on CNS immune regulation and neurodegenerative diseases

Li, L., Lv, L., Wang, Z., Liu, X., Wang, Q., Zhu, H., Jiang, B., Han, Y., Pan, X., Zhou, X., et al. (2025) · Frontiers in Neurology · doi:10.3389/fneur.2025.1581045 · Cited by 9 · see citing works

Unravelling the Alzheimer's pathogenesis: Molecular and cellular pathways to neurodegeneration and therapeutic targets.

Chauhan, P., Wadhwa, K., & Singh, G. (2025) · Pathology, Research and Practice · doi:10.1016/j.prp.2025.156109 · Cited by 6 · see citing works

Cuproptosis: mechanisms and links with Alzheimer’s disease

Zheng, N., Zhou, Q., Chen, Z., Xie, L., Yang, X., Chen, Z., Wang, F., Sun, Q., Du, J., Lin, J., et al. (2025) · Journal of Neurophysiology · doi:10.1152/jn.00370.2025 · Cited by 9 · see citing works

Review on pathogenesis and treatment of Alzheimer's disease

Cai, J., Liu, Y., & Fan, H. (2024) · Developmental Dynamics · doi:10.1002/dvdy.762 · Cited by 9 · see citing works

Identification of a novel pyrrolo[2,3- b ]pyridine compound as a potent glycogen synthase kinase 3β inhibitor for treating Alzheimer’s disease

Xun, Q., Zhang, J., Feng, L., Ma, Y., Li, Y., & Shi, X. (2025) · Journal of Enzyme Inhibition and Medicinal Chemistry · doi:10.1080/14756366.2025.2466846 · Cited by 8 · see citing works

Emerging Insights into Brain Inflammation: Stem-Cell-Based Approaches for Regenerative Medicine

Karam, M., Ortega-Gascó, A., & Tornero, D. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26073275 · Cited by 10 · see citing works

Aging-Associated Amyloid-β Plaques and Neuroinflammation in Bottlenose Dolphins (Tursiops truncatus) and Novel Cognitive Health-Supporting Roles of Pentadecanoic Acid (C15:0)

Venn-Watson, S. K., & Jensen, E. D. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26083746 · Cited by 8 · see citing works

Novel Copper Chelators Enhance Spatial Memory and Biochemical Outcomes in Alzheimer’s Disease Model

Camargo, M. L. M., Farias, A. B., Bertazzo, G. B., Gomes, R. N., Gomes, K. S., Bosquetti, L. M., Takada, S. H., Braga, F. C., Augusto, C. C., Batista, B. L., et al. (2025) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.5c00291 · Cited by 8 · see citing works

Unlocking the in vitro neuroprotection of sloe residues phenolic extracts by bioanalytical and chemometric strategies

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Exploiting the potential of rivastigmine-melatonin derivatives as multitarget metal-modulating drugs for neurodegenerative diseases

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The up-regulation of PTBP1 expression level in patients with Insomnia by senile dementia and promote cuproptosis of nerve cell by SLC31A1

Wang, J., Zhao, X., Han, B., Meng, K., & Gao, L. (2025) · Sleep Medicine · doi:10.1016/j.sleep.2025.01.025 · Cited by 7 · see citing works

A novel carbamate-based hybrid derivative with anti-neuroinflammatory properties as a selective butyrylcholinesterase inhibitor for Alzheimer's disease therapy

Liu, X., Xu, J., Yu, C., Dai, C., Chen, J., Zhong, J., Yang, Y., Lin, H., Chen, X., Zhang, Q., et al. (2025) · Bioorganic Chemistry · doi:10.1016/j.bioorg.2025.108551 · Cited by 7 · see citing works

Iron species in cerebrospinal fluid and dementia risk in subjects with mild cognitive impairment: A cohort study

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Cu(II) Specifically Disassembles Insulin Amyloid Nanostructures via Direct Interaction with Cross-β Fibrils

Mittal, S., Prajapati, K. P., Ansari, M., Joshi, K., Mishra, N., Mahato, O. P., Anand, B. G., & Kar, K. (2024) · Nano Letters · doi:10.1021/acs.nanolett.4c00113 · Cited by 7 · see citing works

Implications of liquid-liquid phase separation and ferroptosis in Alzheimer's disease

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Enhanced activation of retinal progenitor cells by zinc silicate bioceramics for effective functional restoration in retinal degenerative diseases

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Emerging concepts towards a translational framework in Alzheimer’s disease

Cozachenco, D., Zimmer, E. R., & Lourenco, M. V. (2023) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2023.105246 · Cited by 7 · see citing works

Metal ions influx is a double edged sword for the pathogenesis of Alzheimer’s disease

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Targeting Metals in Alzheimer’s Disease: An Update

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Metal Chelators

Rehman, F. (2025) · CRC Press eBooks · doi:10.1201/9781003602477-14

Metal Ions in Alzheimer’s Disease: A Key Role or Not?

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Role of metals in Alzheimer’s disease

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