A randomized controlled trial of internet-based therapy in depression
Abstract
Depression is among the most prevalent disorders worldwide. In view of numerous treatment barriers, internet-based interventions are increasingly adopted to "treat the untreated". The present trial (registered as NCT01401296) was conducted over the internet and aimed to assess the efficacy of an online self-help program for depression (Deprexis). In random order, participants with elevated depression symptoms received program access or were allocated to a wait-list control condition. After eight weeks, participants were invited to take part in an online re-assessment. To compensate for common problems of online studies, such as low completion rates and unclear diagnostic status, reminders and incentives were used, and clinical diagnoses were externally confirmed in a subgroup of 29% of participants. Relative to the wait-list group, program users experienced significant symptom decline on the Beck Depression Inventory (BDI; primary outcome), the Dysfunctional Attitudes Scale (DAS), the Quality of Life scale (WHOQOL-BREF) and the Rosenberg Self-Esteem Scale (RSE). Compared to wait-list participants, symptom decline was especially pronounced among those with moderate symptoms at baseline as well as those not currently consulting a therapist. Completion (82%) and re-test reliability of the instruments (r = .72-.87) were good. The results of this trial suggest that online treatment can be beneficial for people with depression, particularly for those with moderate symptoms.
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Online treatment is clearly better than nothing, according to recent studies.
“online treatment is clearly better than nothing, according to recent studies. [17-19,32]”
From The more it is needed, the less it is wanted: Attitudes toward face-to-face intervention among depressed patients undergoing online treatment (2013) · cites this paper as [19]
We have previously shown that initial expectancies can facilitate treatment engagement and, via this mediating pathway, enhance outcome.
“We have previously shown that initial expectancies can facilitate treatment engagement and, via this mediating pathway, enhance outcome. [19,33]”
From The more it is needed, the less it is wanted: Attitudes toward face-to-face intervention among depressed patients undergoing online treatment (2013) · cites this paper as [19]
The retest reliability of the PECHI as well as other instruments (see [19]) was good and the completion rate was high, confirming the quality of the data.
“Furthermore, the retest reliability of the PECHI as well as other instruments (see [19]) was good and the completion rate was high, confirming the quality of the data.”
From The more it is needed, the less it is wanted: Attitudes toward face-to-face intervention among depressed patients undergoing online treatment (2013) · cites this paper as [19]
Cites
Hamilton, M. (1960) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.23.1.56 · Cited by 32,817 · see citing works
Psychometric properties of the Beck Depression Inventory: Twenty-five years of evaluation
Beck, A. T., Steer, R. A., & Carbin, M. G. (1988) · Clinical Psychology Review · doi:10.1016/0272-7358(88)90050-5 · Cited by 11,696 · see citing works
GPOWER: A general power analysis program
Erdfelder, E., Faul, F., & Buchner, A. (1996) · Behavior Research Methods, Instruments, & Computers · doi:10.3758/bf03203630 · Cited by 4,864 · see citing works
Skevington, S. M., Lotfy, M., & O'Connell, K. A. (2004) · Quality of Life Research · doi:10.1023/b:qure.0000018486.91360.00 · Cited by 4,686 · see citing works
Osman, A., Bagge, C. L., Gutierrez, P. M., Konick, L. C., Kopper, B. A., & Barrios, F. X. (2001) · Assessment · doi:10.1177/107319110100800409 · Cited by 2,276 · see citing works
Analysing controlled trials with baseline and follow up measurements
Vickers, A. J., & Altman, D. G. (2001) · BMJ · doi:10.1136/bmj.323.7321.1123 · Cited by 2,116 · see citing works
The client satisfaction questionnaire
Attkisson, C. C., & Zwick, R. (1982) · Evaluation and Program Planning · doi:10.1016/0149-7189(82)90074-x · Cited by 1,743 · see citing works
The global burden of disease, 1990–2020
López, A. D., & Murray, C. C. J. L. (1998) · Nature Medicine · doi:10.1038/3218 · Cited by 1,613 · see citing works
Treatment gap in mental health care.
Abramowitz, M. Z., Greenberg, D., & Levav, I. (2008) · PubMed · Cited by 1,482 · see citing works
The treatment gap in mental health care.
(2004) · Europe PMC (PubMed Central) · Cited by 1,419 · see citing works
Internet-Based and Other Computerized Psychological Treatments for Adult Depression: A Meta-Analysis
Andersson, G., & Cuijpers, P. (2009) · Cognitive Behaviour Therapy · doi:10.1080/16506070903318960 · Cited by 1,368 · see citing works
Rebooting psychotherapy research and practice to reduce the burden of mental illness
Kazdin, A. E., & Blase, S. L. (2011) · Perspectives on Psychological Science · doi:10.1177/1745691610393527 · Cited by 1,254 · see citing works
The increasing burden of depression
Briley, M., & Lépine (2011) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s19617 · Cited by 1,222 · see citing works
Shafer, A. B. (2006) · Journal of Clinical Psychology · doi:10.1002/jclp.20213 · Cited by 837 · see citing works
A simple sample size formula for analysis of covariance in randomized clinical trials
Borm, G. F., Fransen, J., & Lemmens, W. A. J. G. (2007) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2007.02.006 · Cited by 579 · see citing works
Mind the gap: improving the dissemination of CBT
Shafran, R., Clark, D. M., Fairburn, C. G., Arntz, A., Barlow, D. H., Ehlers, A., Freeston, M., Garety, P. A., Hollon, S. D., Ost, L. G., et al. (2009) · Behaviour Research and Therapy · doi:10.1016/j.brat.2009.07.003 · Cited by 569 · see citing works
Treatment and prevention of depression
Hollon, S. D., Thase, M. E., & Markowitz, J. C. (2002) · Psychological Science in the Public Interest · doi:10.1111/1529-1006.00008 · Cited by 511 · see citing works
Kessler, R. C., Merikangas, K. R., & Wang, P. S. (2007) · Annual Review of Clinical Psychology · doi:10.1146/annurev.clinpsy.3.022806.091444 · Cited by 468 · see citing works
Depression Care in the United States: Too Little for Too Few
González, H. M., Vega, W. A., Williams, D. R., Tarraf, W., West, B. T., & Neighbors, H. W. (2010) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2009.168 · Cited by 418 · see citing works
Berger, T., Hämmerli, K., Gubser, N., Andersson, G., & Caspar, F. (2011) · Cognitive Behaviour Therapy · doi:10.1080/16506073.2011.616531 · Cited by 383 · see citing works
Cuijpers, P., Li, J., Hofmann, S. G., & Andersson, G. (2010) · Clinical Psychology Review · doi:10.1016/j.cpr.2010.06.001 · Cited by 383 · see citing works
Clarke, G., Eubanks, D., Reid, E., Kelleher, C., O'Connor, E., DeBar, L. L., Lynch, F., Nunley, S., & Gullion, C. (2005) · Journal of Medical Internet Research · doi:10.2196/jmir.7.2.e16 · Cited by 372 · see citing works
Meyer, B., Berger, T., Caspar, F., Beevers, C. G., Andersson, G., & Weiss, M. (2009) · Journal of Medical Internet Research · doi:10.2196/jmir.1151 · Cited by 363 · cited 5× · see citing works
“85) and larger, in fact, than in a previous, similar study (Meyer et al., 2009), the post-treatment difference in depression reduction between the treatment and control groups was only small to medium in magnitude (d 1⁄4 .”
BackgroundResultInfluentialPerceived barriers to psychological treatments and their relationship to depression
Mohr, D. C., Ho, J., Duffecy, J., Baron, K. G., Lehman, K. A., Jin, L., & Reifler, D. (2010) · Journal of Clinical Psychology · doi:10.1002/jclp.20659 · Cited by 347 · cited 1× · see citing works
“Common barriers to treatment include (perceived) stigma, lack of motivation for change, negative evaluations of psychotherapy and/or drug treatment, time constraints and costs (Bradley, McGrath, Brannen, & Bagnell, 2010; Mohr et al., 2010; Segal, Coolidge, Mincic, & O’Riley, 2005; Vanheusden et al., 2008).”
BackgroundPsychological treatment of depression: Results of a series of meta-analyses
Cuijpers, P., Andersson, G., Donker, T., & van Straten, A. (2011) · Nordic Journal of Psychiatry · doi:10.3109/08039488.2011.596570 · Cited by 335 · see citing works
Dose-effect relations and responsive regulation of treatment duration: The good enough level.
Barkham, M., Connell, J., Stiles, W. B., Miles, J. N. V., Margison, F., Evans, C., & Mellor-Clark, J. (2006) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.74.1.160 · Cited by 293 · see citing works
Christensen, H., Griffiths, K. M., & Korten, A. (2002) · Journal of Medical Internet Research · doi:10.2196/jmir.4.1.e3 · Cited by 292 · see citing works
Clarke, G., Reid, E., Eubanks, D., O'Connor, E., DeBar, L. L., Kelleher, C., Lynch, F., & Nunley, S. (2002) · Journal of Medical Internet Research · doi:10.2196/jmir.4.3.e14 · Cited by 256 · see citing works
Self-guided psychological treatment for depressive symptoms: a meta-analysis
Cuijpers, P., Donker, T., Johansson, R., Mohr, D. C., van Straten, A., & Andersson, G. (2011) · PLoS ONE · doi:10.1371/journal.pone.0021274 · Cited by 250 · see citing works
Doherty, D. T., & Kartalova‐O'Doherty, Y. (2010) · British Journal of Health Psychology · doi:10.1348/135910709x457423 · Cited by 221 · see citing works
Help-seeking behaviour in patients with anxiety disorder and depression
Roness, A., Mykletun, A., & Dahl, A. A. (2005) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.2004.00433.x · Cited by 197 · see citing works
Dimensionality and norms of the Rosenberg Self-Esteem Scale in a German general population sample
Roth, M., Decker, O., Herzberg, P. Y., & Brähler, E. (2008) · European Journal of Psychological Assessment · doi:10.1027/1015-5759.24.3.190 · Cited by 166 · see citing works
Beliefs about mental illness and willingness to seek help: a cross-sectional study
Segal, D. L., Coolidge, F. L., Mincic, M. S., & O'Riley, A. (2005) · Aging & Mental Health · doi:10.1080/13607860500131047 · Cited by 162 · see citing works
Internet-delivered psychotherapy for depression in adults
Titov, N. (2011) · Current Opinion in Psychiatry · doi:10.1097/yco.0b013e32833ed18f · Cited by 158 · see citing works
Clarke, G., Kelleher, C., Hornbrook, M., DeBar, L., Dickerson, J., & Gullion, C. (2009) · Cognitive Behaviour Therapy · doi:10.1080/16506070802675353 · Cited by 154 · see citing works
Young adults face major barriers to seeking help from mental health services
Vanheusden, K., Mulder, C. L., van der Ende, J., van Lenthe, F. J., Mackenbach, J. P., & Verhulst, F. C. (2008) · Patient Education and Counseling · doi:10.1016/j.pec.2008.05.006 · Cited by 152 · see citing works
Self-help with minimal therapist contact for obsessive–compulsive disorder: a review
Mataix‐Cols, D., & Marks, I. M. (2005) · European Psychiatry · doi:10.1016/j.eurpsy.2005.07.003 · Cited by 146 · see citing works
Moritz, S., Jelinek, L., Hauschildt, M., & Naber, D. (2010) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2010.12.2/smoritz · Cited by 113 · see citing works
Self-citationThe Dysfunctional Attitude Scale: how well can it measure depressive thinking
Nelson, L. D., Stern, S. L., & Cicchetti, D. V. (1992) · Journal of Psychopathology and Behavioral Assessment · doi:10.1007/bf00962629 · Cited by 87 · see citing works
Relationships among personality, expectations about counseling, and help-seeking attitudes
Kakhnovets, R. (2011) · Journal of Counseling & Development · doi:10.1002/j.1556-6678.2011.tb00056.x · Cited by 85 · see citing works
Handbook of Treating Variants and Complications in Anxiety Disorders
Storch, E. A., & McKay, D. (2013) · Springer eBooks · doi:10.1007/978-1-4614-6458-7 · Cited by 82 · see citing works
(2009) · Psychologist · Cited by 78 · see citing works
Harwood, T. M., & L'Abate, L. (2010) · doi:10.1007/978-1-4419-1099-8 · Cited by 69 · see citing works
Stability of the CORE‐OM and the BDI‐I prior to therapy: Evidence from routine practice
Barkham, M., Mullin, T., Leach, C., Stiles, W. B., & Lucock, M. P. (2006) · Psychology and Psychotherapy Theory Research and Practice · doi:10.1348/147608306x148048 · Cited by 58 · see citing works
Ambulante psychotherapeutische Versorgung bei Zwangserkrankungen
Külz, A. K., Hassenpflug, K., Riemann, D. W., Linster, H. W., Dornberg, M., & Voderholzer, U. (2009) · PPmP - Psychotherapie · Psychosomatik · Medizinische Psychologie · doi:10.1055/s-0029-1202837 · Cited by 53 · see citing works
Stationäre psychiatrisch-psychotherapeutische Depressionsbehandlung
Härter, M. C., Sitta, P., Keller, F., Metzger, R., Wiegand, W., Schell, G., Stieglitz, R., Wolfersdorf, M., Felsenstein, M., & Berger, T. (2004) · Der Nervenarzt · doi:10.1007/s00115-004-1705-8 · Cited by 51 · see citing works
Movement decoupling: A self-help intervention for the treatment of trichotillomania.
Moritz, S., & Rufer, M. (2011) · Journal of Behavior Therapy and Experimental Psychiatry · doi:10.1016/j.jbtep.2010.07.001 · Cited by 50 · see citing works
Adolescents’ attitudes and opinions about depression treatment
Bradley, K. L., McGrath, P. J., Brannen, C. L., & Bagnell, A. L. (2010) · Community Mental Health Journal · doi:10.1007/s10597-009-9224-5 · Cited by 50 · see citing works
Emotion‐Focused Cognitive Therapy
Power, M. (2010) · Wiley eBooks · doi:10.1002/9780470660065 · Cited by 45 · see citing works
‘A coal face option’: GPs' perspectives on the rise in antidepressant prescribing
Macdonald, S., Morrison, J., Maxwell, M., Munoz-Arroyo, R., Power, A., Smith, M. S., Sutton, M., & Wilson, P. (2009) · British Journal of General Practice · doi:10.3399/bjgp09x454106 · Cited by 43 · see citing works
Rosner, R. I., Lyddon, W. J., & Freeman, A. (2003) · Cited by 39 · see citing works
Moritz, S., Aravena, S. C., Guczka, S. R., Schilling, L., Eichenberg, C., Raubart, G., Seebeck, A., & Jelinek, L. (2011) · Journal of Behavior Therapy and Experimental Psychiatry · doi:10.1016/j.jbtep.2010.07.002 · Cited by 32 · see citing works
Are Randomized Controlled Trials Relevant to Clinical Practice?
Hollon, S. D., & Wampold, B. E. (2009) · The Canadian Journal of Psychiatry · doi:10.1177/070674370905400909 · Cited by 23 · see citing works
Short-Term Spontaneous Improvement Rates in Depressed Outpatients
Posternak, M. A., & Zimmerman, M. A. (2000) · The Journal of Nervous and Mental Disease · doi:10.1097/00005053-200012000-00002 · Cited by 19 · see citing works
Flagged first, then by citations
1 of the 55 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Karyotaki, E., Efthimiou, O., Miguel, C., Maas genannt Bermpohl, F., Furukawa, T. A., Cuijpers, P., Individual Patient Data Meta-Analyses for Depression (IPDMA-DE) Collaboration, Riper, H., Patel, V., Mira, A., et al. (2021) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2020.4364 · Cited by 866 · see citing works
Karyotaki, E., Riper, H., Twisk, J., Hoogendoorn, A., Kleiboer, A., Mira, A., Mackinnon, A., Meyer, B., Botella, C., Littlewood, E., et al. (2017) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2017.0044 · Cited by 691 · see citing works
Digital interventions for the treatment of depression: a meta-analytic review
Moshe, I., Terhorst, Y., Philippi, P., Domhardt, M., Cuijpers, P., Cristea, I., Pulkki-Råback, L., Baumeister, H., & Sander, L. B. (2021) · Psychological Bulletin · doi:10.1037/bul0000334 · Cited by 390 · see citing works
Karyotaki, E., Kleiboer, A., Smit, F., Turner, D. T., Pastor, A. M., Andersson, G., Berger, T., Botella, C., Breton, J. M., Carlbring, P., et al. (2015) · Psychological Medicine · doi:10.1017/s0033291715000665 · Cited by 408 · see citing works
Torok, M., Han, J., Baker, S., Werner-Seidler, A., Wong, I., Larsen, M. E., & Christensen, H. (2020) · The Lancet Digital Health · doi:10.1016/s2589-7500(19)30199-2 · Cited by 273 · see citing works
Witt, K., Spittal, M. J., Carter, G., Pirkis, J., Hetrick, S., Currier, D., Robinson, J., & Milner, A. (2017) · BMC Psychiatry · doi:10.1186/s12888-017-1458-0 · Cited by 179 · see citing works
Meyer, B., Bierbrodt, J., Schröder, J., Berger, T., Beevers, C. G., Weiss, M., Jacob, G., Späth, C., Andersson, G., Lutz, W., et al. (2015) · Internet Interventions · doi:10.1016/j.invent.2014.12.003 · Cited by 188 · see citing works
Karyotaki, E., Kemmeren, L., Riper, H., Twisk, J., Hoogendoorn, A., Kleiboer, A., Mira, A., Mackinnon, A., Meyer, B., Botella, C., et al. (2018) · Psychological Medicine · doi:10.1017/s0033291718000648 · Cited by 167 · see citing works
Gamification and Adherence to Web-Based Mental Health Interventions: A Systematic Review
Brown, M., O'Neill, N., van Woerden, H., Eslambolchilar, P., Jones, M., & John, A. (2016) · JMIR Mental Health · doi:10.2196/mental.5710 · Cited by 178 · see citing works
Carter, G., Page, A., Large, M., Hetrick, S., Milner, A. J., Bendit, N., Walton, C., Draper, B., Hazell, P., Fortune, S., et al. (2016) · Australian & New Zealand Journal of Psychiatry · doi:10.1177/0004867416661039 · Cited by 167 · see citing works
Lim, S. M., Shiau, C. W. C., Cheng, L. J., & Lau, Y. (2022) · Behavior Therapy · doi:10.1016/j.beth.2021.09.007 · Cited by 163 · see citing works
Schröder, J., Sautier, L., Kriston, L., Berger, T., Meyer, B., Späth, C., Köther, U., Nestoriuc, Y., Klein, J. P., & Moritz, S. (2015) · Journal of Affective Disorders · doi:10.1016/j.jad.2015.08.044 · Cited by 149 · see citing works
Hallgren, M. Å., Kraepelien, M., Öjehagen, A., Lindefors, N., Zeebari, Z., Kaldo, V., & Forsell, Y. (2015) · The British Journal of Psychiatry · doi:10.1192/bjp.bp.114.160101 · Cited by 163 · see citing works
Guille, C., Zhao, Z., Krystal, J. H., Nichols, B., Brady, K. T., & Sen, S. (2015) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2015.1880 · Cited by 164 · see citing works
Berger, T., Krieger, T., Sude, K., Meyer, B., & Maercker, A. (2018) · Journal of Affective Disorders · doi:10.1016/j.jad.2017.11.021 · Cited by 153 · see citing works
Klein, J. P., Berger, T., Schröder, J., Späth, C., Meyer, B., Caspar, F., Lutz, W., Arndt, A., Greiner, W., Gräfe, V., et al. (2016) · Psychotherapy and Psychosomatics · doi:10.1159/000445355 · Cited by 145 · see citing works
Fischer, A., Schröder, J., Vettorazzi, E., Wolf, O. T., Pöttgen, J., Lau, S., Heesen, C., Moritz, S., & Gold, S. M. (2015) · The Lancet Psychiatry · doi:10.1016/s2215-0366(14)00049-2 · Cited by 143 · see citing works
Self-citationE-Health Interventions for Suicide Prevention
Christensen, H. M., Batterham, P. J., & O’Dea, B. (2014) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph110808193 · Cited by 139 · see citing works
Internet interventions for depression: new developments
Schröder, J., Berger, T., Westermann, S., Klein, J. P., & Moritz, S. (2016) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2016.18.2/jschroeder · Cited by 105 · see citing works
Self-citationTwomey, C., O’Reilly, G., & Meyer, B. (2017) · Psychiatry Research · doi:10.1016/j.psychres.2017.06.081 · Cited by 103 · see citing works
Berger, T., Urech, A., Krieger, T., Stolz, T., Schulz, A., Vincent, A., Moser, C. T., Moritz, S., & Meyer, B. (2017) · Psychological Medicine · doi:10.1017/s0033291716002270 · Cited by 98 · see citing works
“…was developed by Gaia AG, Hamburg, Germany, an e-Health company that has developed several previous Internet interventions, including ‘deprexis’, a depression-focused programme that has been tested in several RCTs (e.g. Meyer et al. 2009; Berger et al. 2011b; Moritz et al. 2012; Klein et al. 2016).”
MethodSchröder, J., Brückner, K., Fischer, A., Lindenau, M., Köther, U., Vettorazzi, E., & Moritz, S. (2014) · Epilepsia · doi:10.1111/epi.12833 · Cited by 96 · see citing works
Self-citationForbes, A., Keleher, M. R., Venditto, M., & DiBiasi, F. (2023) · Journal of Medical Internet Research · doi:10.2196/43727 · Cited by 94 · see citing works
Reme, S. E., Sveinsdóttir, V. Ó., & Eriksen (2012) · Journal of Pain Research · doi:10.2147/jpr.s25330 · Cited by 87 · see citing works
Mental health related Internet use among psychiatric patients: a cross-sectional analysis
Kalckreuth, S., Trefflich, F., & Rummel-Kluge, C. (2014) · BMC Psychiatry · doi:10.1186/s12888-014-0368-7 · Cited by 86 · see citing works
Twomey, C. D., O’Reilly, G., Bültmann, O., & Meyer, B. (2020) · PLoS ONE · doi:10.1371/journal.pone.0228100 · Cited by 75 · see citing works
Andrews, G., & Williams, A. D. (2015) · Clinical Psychology Review · doi:10.1016/j.cpr.2014.05.006 · Cited by 80 · see citing works
Beevers, C. G., Pearson, R., Hoffman, J. S., Foulser, A. A., Shumake, J., & Meyer, B. (2017) · Journal of Consulting and Clinical Psychology · doi:10.1037/ccp0000171 · Cited by 69 · see citing works
Jabir, A. I., Lin, X., Martinengo, L., Sharp, G., Theng, Y. L., & Car, L. T. (2023) · Journal of Medical Internet Research · doi:10.2196/48168 · Cited by 70 · see citing works
Wagner, B., Klinitzke, G., Brähler, E., & Kersting, A. (2013) · Depression and Anxiety · doi:10.1002/da.22105 · Cited by 59 · see citing works
Moritz, S., Schröder, J., Meyer, B., & Hauschildt, M. (2013) · Depression and Anxiety · doi:10.1002/da.21988 · Cited by 53 · see citing works
Schure, M. B., Lindow, J. C., Greist, J. H., Nakonezny, P. A., Bailey, S. J., Bryan, W. L., & Byerly, M. (2019) · Journal of Medical Internet Research · doi:10.2196/14754 · Cited by 50 · see citing works
Acceptability of Digital Mental Health Interventions for Depression and Anxiety: Systematic Review
Lau, C. K. Y., Saad, A., Camara, B., Rahman, D., & Bolea-Alamanac, B. (2024) · Journal of Medical Internet Research · doi:10.2196/52609 · Cited by 51 · see citing works
Bücker, L., Bierbrodt, J., Hand, I., Wittekind, C., & Moritz, S. (2018) · PLoS ONE · doi:10.1371/journal.pone.0198859 · Cited by 50 · see citing works
Wahle, F., Bollhalder, L., Kowatsch, T., & Fleisch, E. (2017) · Journal of Medical Internet Research · doi:10.2196/jmir.7381 · Cited by 48 · see citing works
Schulze, N., Reuter, S. C., Kuchler, I., Reinke, B., Hinkelmann, L., Stöckigt, S., Siemoneit, H., & Tonn, P. (2019) · Telemedicine and e-Health · doi:10.1089/tmj.2018.0225 · Cited by 48 · see citing works
Can We Trust the Internet to Measure Psychotic Symptoms?
Moritz, S., Quaquebeke, N. V., Lincoln, T. M., Köther, U., & Andreou, C. (2013) · Schizophrenia Research and Treatment · doi:10.1155/2013/457010 · Cited by 47 · see citing works
Online psychotherapy: trailblazing digital healthcare
McDonald, A., Eccles, J. A., Fallahkhair, S., & Critchley, H. D. (2020) · BJPsych Bulletin · doi:10.1192/bjb.2019.66 · Cited by 45 · see citing works
Internet‐Based Psychotherapy for Adult Depression: What About the Mechanisms of Change?
Mogoaşe, C., Cobeanu, O., David, D., Giosan, C., & Szentágotai, A. (2016) · Journal of Clinical Psychology · doi:10.1002/jclp.22326 · Cited by 45 · see citing works
Lantzsch, H., Eckhardt, H., Campione, A., Busse, R., & Henschke, C. (2022) · BMC Health Services Research · doi:10.1186/s12913-022-08500-6 · Cited by 44 · see citing works
Kolominsky‐Rabas, P. L., Tauscher, M., Gerlach, R., Perleth, M., & Dietzel, N. (2022) · Zeitschrift für Evidenz Fortbildung und Qualität im Gesundheitswesen · doi:10.1016/j.zefq.2022.09.008 · Cited by 44 · see citing works
Sander, L., Gerhardinger, K., Bailey, E., Robinson, J., Lin, J., Cuijpers, P. J., & Mühlmann, C. (2019) · Journal of Affective Disorders · doi:10.1016/j.jad.2019.11.045 · Cited by 44 · see citing works
McCall, H. C., Hadjistavropoulos, H. D., & Sundström, C. (2021) · Journal of Medical Internet Research · doi:10.2196/26939 · Cited by 39 · see citing works
Shim, E., Noh, H. L., Yoon, J.-M., Mun, H. S., & Hahm, B. (2018) · Journal of American College Health · doi:10.1080/07448481.2018.1462819 · Cited by 39 · see citing works
Schröder, J., Werkle, N., Cludius, B., Jelinek, L., Moritz, S., & Westermann, S. (2020) · Depression and Anxiety · doi:10.1002/da.23105 · Cited by 40 · see citing works
Nagamitsu, S., Kanie, A., Sakashita, K., Sakuta, R., Okada, A., Matsuura, K., Ito, M., Katayanagi, A., Katayama, T., Otani, R., et al. (2022) · JMIR mhealth and uhealth · doi:10.2196/34154 · Cited by 38 · see citing works
Are digital interventions effective in reducing suicidal ideation and self-harm? A systematic review
Stefanopoulou, E., Hogarth, H., Taylor, M., Russell-Haines, K., Lewis, D., & Larkin, J. (2020) · Journal of Mental Health · doi:10.1080/09638237.2020.1714009 · Cited by 37 · see citing works
Lin, A., & Espay, A. J. (2021) · Epilepsy & Behavior Reports · doi:10.1016/j.ebr.2021.100469 · Cited by 38 · see citing works
Zippan, N., Stephenson, K. R., & Brotto, L. A. (2020) · The Journal of Sexual Medicine · doi:10.1016/j.jsxm.2020.07.086 · Cited by 37 · see citing works
Krieger, T., Meyer, B., Sude, K., Urech, A., Maercker, A. R. A., & Berger, T. (2014) · BMC Psychiatry · doi:10.1186/s12888-014-0285-9 · Cited by 33 · see citing works
Høifødt, R. S., Mittner, M., Lillevoll, K. R., Katla, S. K., Kolstrup, N., Eisemann, M. R., Friborg, O., & Waterloo, K. K. (2015) · Journal of Medical Internet Research · doi:10.2196/jmir.4351 · Cited by 33 · see citing works
Schneider, B. C., Schröder, J., Berger, T., Hohagen, F., Meyer, B., Späth, C., Greiner, W., Hautzinger, M., Lutz, W., Rose, M., et al. (2018) · Journal of Affective Disorders · doi:10.1016/j.jad.2018.04.101 · Cited by 32 · see citing works
Self-citationHeterogeneity of Treatment Effects in Internet- and Mobile-Based Interventions for Depression
Terhorst, Y., Kaiser, T., Brakemeier, E., Moshe, I., Philippi, P., Cuijpers, P. J., Baumeister, H., & Sander, L. (2024) · JAMA Network Open · doi:10.1001/jamanetworkopen.2024.23241 · Cited by 32 · see citing works
Haaf, R., Vock, P., Wächtershäuser, N., Correll, C. U., Köhler, S., & Klein, J. P. (2024) · Der Nervenarzt · doi:10.1007/s00115-023-01587-0 · Cited by 30 · see citing works
Digital Technology for Suicide Prevention
Braciszewski, J. M. (2021) · Advances in Psychiatry and Behavioral Health · doi:10.1016/j.ypsc.2021.05.008 · Cited by 28 · see citing works
Bücker, L., Schnakenberg, P., Karyotaki, E., Moritz, S., & Westermann, S. (2019) · Journal of Medical Internet Research · doi:10.2196/14240 · Cited by 27 · see citing works
Psychenet.de: development and process evaluation of an e-mental health portal
Dirmaier, J., Liebherz, S., Sänger, S., Härter, M. C., & Tlach, L. (2015) · Informatics for Health and Social Care · doi:10.3109/17538157.2015.1008486 · Cited by 27 · see citing works
Jackson, H. M., Calear, A. L., Batterham, P. J., Ohan, J. L., Farmer, G. M., & Farrer, L. M. (2023) · Journal of Medical Internet Research · doi:10.2196/44673 · Cited by 25 · see citing works
Klein, J. P., Späth, C., Schröder, J., Meyer, B., Greiner, W., Hautzinger, M., Lutz, W., Rose, M., Vettorazzi, E., Andersson, G., et al. (2017) · Behaviour Research and Therapy · doi:10.1016/j.brat.2017.07.013 · Cited by 25 · see citing works
Zhao, D., Lustria, M. L. A., & Hendrickse, J. (2017) · Patient Education and Counseling · doi:10.1016/j.pec.2017.01.004 · Cited by 24 · see citing works
Gräfe, V., Moritz, S., & Greiner, W. (2020) · Health Economics Review · doi:10.1186/s13561-020-00273-0 · Cited by 22 · see citing works
Richards, D., Duffy, D. J., Burke, J., Anderson, M., Connell, S., & Timulák, L. (2018) · JMIR Mental Health · doi:10.2196/10204 · Cited by 23 · see citing works
Maj, A., Michalak, N., Graczykowska, A., & Andersson, G. (2023) · Internet Interventions · doi:10.1016/j.invent.2023.100654 · Cited by 22 · see citing works
Digital health applications in the area of mental health
Schreiter, S., Mascarell-Maricic, L., Rakitzis, O., Volkmann, C., Kaminski, J. A., & Daniels, M. A. (2023) · Deutsches Ärzteblatt international · doi:10.3238/arztebl.m2023.0208 · Cited by 24 · see citing works
Lau, Y., Ang, W. H. D., Ang, W. W., Pang, P. C., Wong, S. H., & Chan, K. S. (2025) · Depression and Anxiety · doi:10.1155/da/8930012 · Cited by 22 · see citing works
Jesús-Romero, R. D., Holder-Dixon, A. R., Buss, J. F., & Lorenzo-Luaces, L. (2023) · Journal of Medical Internet Research · doi:10.2196/50780 · Cited by 36 · see citing works
Weymann, N., Härter, M. C., Petrak, & Dirmaier, J. (2013) · Patient Preference and Adherence · doi:10.2147/ppa.s46924 · Cited by 22 · see citing works
Messerli‐Bürgy, N., Barth, J., & Berger, T. (2012) · Trials · doi:10.1186/1745-6215-13-245 · Cited by 22 · see citing works
Positive Youth Development and Foster Care Youth: A Digital Perspective
Gustavsson, N. S., & MacEachron, A. E. (2015) · Journal of Human Behavior in the Social Environment · doi:10.1080/10911359.2014.966223 · Cited by 22 · see citing works
Pang, Y., Zhang, X., Gao, R., Xu, L., Shen, M., Shi, H., Li, Y., & Li, F. (2021) · BMC Psychiatry · doi:10.1186/s12888-021-03396-8 · Cited by 21 · see citing works
Ghosh, A., Cherian, R. J., Wagle, S., Sharma, P., Kannan, K. R., Bajpai, A., & Gupta, N. (2023) · Journal of Medical Internet Research · doi:10.2196/41005 · Cited by 23 · see citing works
Chen, M., & Chan, K. L. (2020) · Trauma Violence & Abuse · doi:10.1177/1524838020967346 · Cited by 19 · see citing works
Antidepressant Treatment of Depression During Pregnancy and the Postpartum Period
McDonagh, M. S., Matthews, A. M., Phillipi, C. A., Romm, J., Peterson, K., Thakurta, S., & Guise, J. (2014) · doi:10.23970/ahrqepcerta216 · Cited by 19 · see citing works
Tong, A. C. Y., Ho, F. S., Chu, O. H., & Mak, W. W. S. (2023) · Journal of Medical Internet Research · doi:10.2196/39029 · Cited by 19 · see citing works
Brame, J., Kohl, J., Wurst, R., Fuchs, R., Tinsel, I., Maiwald, P., Fichtner, U. A., Armbruster, C., Bischoff, M., Farin‐Glattacker, E., et al. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19031393 · Cited by 17 · see citing works
Lopes, R. D. C. T., da Rocha, G. C., Svacina, M. A., Meyer, B., Šipka, D., & Berger, T. (2023) · JMIR Formative Research · doi:10.2196/46326 · Cited by 14 · see citing works
Ratajska, A. M., Zurawski, J., Healy, B., & Glanz, B. (2019) · International Journal of MS Care · doi:10.7224/1537-2073.2017-094 · Cited by 17 · see citing works
Yang, D., Hur, J.-W., Kwak, Y. B., & Choi, S. (2018) · Psychiatry Investigation · doi:10.30773/pi.2018.03.15 · Cited by 10 · see citing works
Holtdirk, F., Mehnert-Theuerkauf, A., Weiss, M., Meyer, B., & Watzl, C. (2020) · Trials · doi:10.1186/s13063-019-3987-y · Cited by 14 · see citing works
Zill, J. M., Meyer, B., Topp, J., Daubmann, A., Härter, M. C., & Dirmaier, J. (2016) · BMC Psychiatry · doi:10.1186/s12888-016-0725-9 · Cited by 15 · see citing works
Chrzan‐Dętkoś, M., & Walczak‐Kozłowska, T. (2022) · BMC Public Health · doi:10.1186/s12889-022-14705-5 · Cited by 13 · see citing works
Zwerenz, R., Becker, J., Knickenberg, R. J., Hagen, K., Dreier, M., Wölfling, K., & Beutel, M. E. (2015) · Trials · doi:10.1186/s13063-015-0620-6 · Cited by 13 · see citing works
Rothman, B., Slomkowski, M., Speier, A., Rush, A. J., Trivedi, M. H., Lawson, E., Fahmy, M., Carpenter, D., Chen, D., & Forbes, A. (2024) · JMIR Research Protocols · doi:10.2196/56960 · Cited by 12 · see citing works
Meyer, B., Weiss, M., Holtkamp, M., Arnold, S., Brückner, K., Schröder, J., Scheibe, F., & Nestoriuc, Y. (2017) · BMC Psychiatry · doi:10.1186/s12888-017-1229-y · Cited by 12 · see citing works
Chen, Y.-L., Pan, A., Hsiung, P., & Chung, L. (2015) · Hong Kong Journal of Occupational Therapy · doi:10.1016/j.hkjot.2015.04.001 · Cited by 12 · see citing works
Courtois, C., & Frissen, T. (2022) · Communication Methods and Measures · doi:10.1080/19312458.2022.2122423 · Cited by 11 · see citing works
Meyerhoff, J., Kruzan, K. P., Kim, K. A., Orden, K. A. V., & Mohr, D. C. (2022) · Archives of Suicide Research · doi:10.1080/13811118.2022.2096520 · Cited by 10 · see citing works
The Effectiveness of Internet-Based Mindfulness Interventions for Physical and Mental Illnesses
Krolikowski, A. (2013) · International Journal of Cyber Behavior Psychology and Learning · doi:10.4018/ijcbpl.2013100106 · Cited by 10 · see citing works
Botella, C., Mira, A., Herrero, R., García‐Palacios, A., & Baños, R. (2015) · Aloma: revista de psicologia, ciències de l'educació i de l'esport Blanquerna · doi:10.51698/aloma.2015.33.2.39-48 · Cited by 10 · see citing works
Demyttenaere, K., Frank, E., Castle, D. J., & Cindik-Herbrüggen, E. (2019) · Advances in Therapy · doi:10.1007/s12325-019-01038-w · Cited by 9 · see citing works
Hayes, J., & Grieve, R. (2013) · Telemedicine Journal and e-Health · doi:10.1089/tmj.2012.0278 · Cited by 9 · see citing works
Castro, Ó., Salamanca-Sanabria, A., Alattas, A., Teepe, G. W., Leidenberger, K., Fleisch, E., Car, L. T., Müller‐Riemenschneider, F., & Kowatsch, T. (2024) · Archives of Public Health · doi:10.1186/s13690-024-01424-z · Cited by 10 · see citing works
Reduced Contact Cognitive-Behavioral Interventions for Adult Depression: A Review
Beshai, S., Wallace, L. M., McDougall, K. H., Waldmann, K., & Stea, J. N. (2016) · The Journal of psychology · doi:10.1080/00223980.2015.1087376 · Cited by 7 · see citing works
da Silva, R. A., Cardoso, T. D. A., Mondin, T. C., Reyes, A. N., Bach, S. D. L., Souza, L. D. D. M., & Jansen, K. (2017) · The Journal of Nervous and Mental Disease · doi:10.1097/nmd.0000000000000758 · Cited by 8 · see citing works
Wolff, L. L., Rapp, M. A., & Mocek, A. (2022) · Psychiatrische Praxis · doi:10.1055/a-1875-3635 · Cited by 8 · see citing works
Peut-on faire une TCC sans thérapeute ? Composantes actives des TCC informatisées pour la dépression
Iakimova, G., Dimitrova, S., & Burté, T. (2016) · L Encéphale · doi:10.1016/j.encep.2016.08.006 · Cited by 31 · see citing works
Lopes, R. D. C. T., Meyer, B., Berger, T., & Svacina, M. A. (2020) · Brazilian Journal of Psychiatry · doi:10.1590/1516-4446-2019-0582 · Cited by 8 · see citing works
Freitag, B., Uncovska, M., Meister, S., Prinz, C., & Fehring, L. (2024) · npj Digital Medicine · doi:10.1038/s41746-024-01324-0 · Cited by 6 · see citing works
Vitale, E., Genovese, V. V., & Allenet, B. (2021) · Education thérapeutique du patient - Therapeutic patient education · doi:10.1051/tpe/2021007 · Cited by 6 · see citing works
Edelbluth, S., Klein, J. P., Schwartz, B., Hehlmann, M. I., Arndt, A., Rubel, J. A., Danilo Moggia, N., Berger, T., Meyer, B., Moritz, S., et al. (2024) · Cognitive Behaviour Therapy · doi:10.1080/16506073.2024.2368520 · Cited by 5 · see citing works
- Authors
- Moritz, S., Schilling, L., Hauschildt, M., Schröder, J., & Treszl, A.
- Affiliations
- University Medical Center Hamburg-Eppendorf (DE)
- Corresponding author
- Moritz, Steffen
- Venue
- Behaviour Research and Therapy
- Publisher
- Elsevier BV
- Published
- 2012-08
- Volume
- 50
- Issue
- 7-8
- Pages
- 513-521
- ISSN
- 0005-7967 (ISSN-L)
- OpenAlex
- W2058124168
- Cited by
- 140
- References
- 55
- Citations by year
- 2026: 2 · 2025: 3 · 2024: 10 · 2023: 11 · 2022: 13 · 2021: 12 · 2020: 9 · 2019: 11 · 2018: 9 · 2017: 15 · 2016: 10 · 2015: 15 · 2014: 10 · 2013: 6 · 2012: 4
- FWCI
- 15.69
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Behaviour Research and Therapy (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Keywords
- online therapy, depression, online self-help program, Deprexis, waitlist control, barriers to treatment, treatment completion, dysfunctional attitudes, quality of life, self-esteem, Beck Depression Inventory, Dysfunctional Attitude Scale, WHOQOL-BREF, Rosenberg Self-Esteem Scale
- MeSH terms
- Adult, Analysis of Variance, Major Depressive Disorder, Female, Humans, Male, Middle Aged, Psychiatric Status Rating Scales, Self Care, Cognitive Behavioral Therapy, Treatment Outcome, Internet
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