Wearable Chemical Sensors: Present Challenges and Future Prospects
Abstract
Wearable sensors have received considerable interest over the past decade owing to their tremendous promise for monitoring the wearers’ health, fitness, and their surroundings. However, only limited attention has been directed at developing wearable chemical sensors that offer more comprehensive information about a wearer’s well-being. The development of wearable chemical sensors faces multiple challenges on various fronts. This perspective reviews key challenges and technological gaps impeding the successful realization of effective wearable chemical sensor systems, related to materials, power, analytical procedure, communication, data acquisition, processing, and security. Size, rigidity, and operational requirements of present chemical sensors are incompatible with wearable technology. Sensor stability and on-body sensor surface regeneration constitute key analytical challenges. Similarly, present wearable power sources are incapable of meeting the requirements for wearable electronics owing to their low energy densities and slow recharging. Several energy-harvesting methodologies have inherent issues, including inconsistent power supply and limited stability. There are also major challenges pertaining to handling and securing the big data generated by wearable sensors. These include achieving high data transfer rates and efficient data mining. Efforts must also be made toward developing next generation cryptologic algorithms for ensuring data security and user privacy. The challenges facing the field of wearable chemical sensors, and wearable sensors, in general, can thus be addressed only by a multidisciplinary approach where researchers from diverse fields work in unison. The article discusses these challenges and their potential solutions along with future prospects.
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Wearable biosensors face many fundamental challenges and technological gaps related to the scope, validation, stability and accuracy, along with power, communication and security/privacy issues.
“Wearable biosensors face many fundamental challenges and technological gaps related to the scope, validation, stability and accuracy, along with power (Box 1)1,42,157-167, communication (Box 2)1,168 and security/privacy issues (Box 3)1,169-172”
From Wearable biosensors for healthcare monitoring (2019) · cites this paper as [1]
Researchers have focused on combination approaches that involve the development of both the power sources and the design of more energy-efficient devices and adaptive algorithms to decrease energy demands.
“Researchers have focused on a combination approaches that involve the development of both the power sources and the design of more energy-efficient devices and adaptive algorithms to decrease energy demands.”
From Wearable biosensors for healthcare monitoring (2019) · cites this paper as [1]
The emergence of IC fabrication strategies, flexible electronics, device design, and e-garments has revolutionized the development of soft electronics and biological and chemical sensor technologies toward advancing sports medicine.
“The emergence of IC fabrication strategies, flexible electronics, device design, and e-garments has revolutionized the development of soft electronics and biological and chemical sensor technologies toward advancing sports medicine.123–127”
From Wearable sensors for monitoring the physiological and biochemical profile of the athlete (2019) · cites this paper as [123]
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Wearable biosensors for healthcare monitoring
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Self-citationRoom Temperature Gas Sensing of Two-Dimensional Titanium Carbide (MXene)
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Self-citationElectrically-Transduced Chemical Sensors Based on Two-Dimensional Nanomaterials
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Functional Fibers and Fabrics for Soft Robotics, Wearables, and Human–Robot Interface
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Wearable chemical sensors for biomarker discovery in the omics era
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Wearable non-invasive epidermal glucose sensors: A review
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Self-citationDetection principles of biological and chemical FET sensors
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Flexible MXene‐Based Composites for Wearable Devices
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Wearable sensors for monitoring the physiological and biochemical profile of the athlete
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Conducting Polymers in the Fields of Energy, Environmental Remediation, and Chemical–Chiral Sensors
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Disruptive, Soft, Wearable Sensors
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Self-citationMedical 4.0 technologies for healthcare: Features, capabilities, and applications
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A Wearable Microfluidic Sensing Patch for Dynamic Sweat Secretion Analysis
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Wearable Electrochemical Sensors for the Monitoring and Screening of Drugs
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Self-citationRoll-to-Roll Gravure Printed Electrochemical Sensors for Wearable and Medical Devices
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Wearable Sensors for Biochemical Sweat Analysis
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Advances in the Application of Magnetic Nanoparticles for Sensing
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The Era of Digital Health: A Review of Portable and Wearable Affinity Biosensors
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Wearable potentiometric ion sensors
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Self-citationEyeglasses based wireless electrolyte and metabolite sensor platform
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Soft Sensors and Actuators for Wearable Human–Machine Interfaces
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On‐Body Bioelectronics: Wearable Biofuel Cells for Bioenergy Harvesting and Self‐Powered Biosensing
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Global chemical analysis of biology by mass spectrometry
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Wearable Chemical Sensors: Emerging Systems for On-Body Analytical Chemistry
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Self-citationMicrofluidic Point-of-Care Devices: New Trends and Future Prospects for eHealth Diagnostics
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Liquid crystals in micron-scale droplets, shells and fibers
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Wearable Electrochemical Biosensors for Advanced Healthcare Monitoring
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Skin in the diagnostics game: Wearable biosensor nano- and microsystems for medical diagnostics
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Wearable-band type visible-near infrared optical biosensor for non-invasive blood glucose monitoring
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Recent Advances in Wearable Transdermal Delivery Systems
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Self-citationMechanistic Challenges and Advantages of Biosensor Miniaturization into the Nanoscale
Soleymani, L., & Li, F. (2017) · ACS Sensors · doi:10.1021/acssensors.7b00069 · Cited by 177 · see citing works
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Energy Autonomous Sweat‐Based Wearable Systems
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- Authors
- Bandodkar, A. J., Jeerapan, I., & Wang, J.
- Affiliations
- University of California San Diego (US)
- Corresponding author
- Wang, Joseph
- Venue
- ACS Sensors
- Publisher
- American Chemical Society (ACS)
- Published
- 2016-05-11
- Volume
- 1
- Issue
- 5
- Pages
- 464-482
- ISSN
- 2379-3694 (ISSN-L)
- OpenAlex
- W2346517120
- Semantic Scholar
- 0a2ab0ac9bd399ade5d2539455300284ffb7c989
- Cited by
- 778
- References
- 249
- Citations by year
- 2026: 54 · 2025: 63 · 2024: 62 · 2023: 66 · 2022: 66 · 2021: 104 · 2020: 106 · 2019: 112 · 2018: 73 · 2017: 56 · 2016: 16
- FWCI
- 41.29
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- ACS Sensors (publishedVersion)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Advanced Sensor and Energy Harvesting Materials
- Physical Sciences › Engineering › Electrical and Electronic Engineering › Electrochemical sensors and biosensors
- Physical Sciences › Chemical Engineering › Bioengineering › Analytical Chemistry and Sensors
- Keywords
- wearable sensors, health monitoring, sensor materials, wearable power sources, energy harvesting, sensor stability, data security, user privacy, data acquisition and processing, data rate
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