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Cited by 370Child and Adolescent Psychosocial and Emotional DevelopmentAnxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesPersonality Disorders and Psychopathology

Clinical characteristics of anxiety disordered youth

Open access
Kendall, Philip C., Compton, Scott N., Walkup, John T., Birmaher, Boris, Albano, Anne Marie, Sherrill, Joel, Ginsburg, Golda, Rynn, Moira +9 more·2010·Journal of Anxiety Disorders
DOI 10.1016/j.janxdis.2010.01.009PMC PMC2838990
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Abstract

Reports the characteristics of a large, representative sample of treatment-seeking anxious youth (N=488). Participants, aged 7-17 years (mean 10.7 years), had a principal DSM-IV diagnosis of separation anxiety disorder (SAD), generalized anxiety disorder (GAD), or social phobia (SP). Although youth with a co-primary diagnosis for which a different disorder-specific treatment would be indicated (e.g., major depressive disorder, substance abuse) were not included, there were few other exclusion criteria. Participants and their parent/guardian underwent an extensive baseline assessment using a broad array of measures capturing diagnostic status, anxiety symptoms and severity, and areas of functional impairment. Means and standard deviations of the measures of psychopathology and data on diagnostic status are provided. The sample had moderate to severe anxiety disorder and was highly comorbid, with 55.3% of participants meeting criteria for at least one non-targeted DSM-IV disorder. Anxiety disorders in youth often do not present as a single/focused disorder: such disorders in youth overlap in symptoms and are highly comorbid among themselves.

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Crossref · 10.1016/j.janxdis.2010.01.009

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  • Children diagnosed with SAD are at increased risk of being diagnosed with other behavioral and emotional disorders, such as attention deficit hyperactivity disorder and depression.

    “Additionally, children diagnosed with SAD are at increased risk of being diagnosed with other behavioral and emotional disorders, such as attention deficit hyperactivity disorder and depression [3].”

    From The risks versus the benefits of pharmacological intervention in social anxiety disorder in children (2025) · cites this paper as [3]

    The Results (Comorbidity; page unavailable) report that 55.33% of the anxiety-disordered sample had an additional diagnosis and that ADHD was among the most common comorbidities. The finding is not specific to children with separation anxiety disorder (SAD), and it does not establish increased risk. The Methods (Participants; page unavailable) state that children with major depressive disorder were excluded, so the paper does not support depression as an example of a co-diagnosis in this sample. (LLM, conf=0.85)

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  • The CAMS study compared CBT and medication but was an efficacy study conducted in academic centers rather than real-world community clinics.

    “(the CAMS study did, but it was an efficacy study conducted in academic centers rather than in “real world” community clinics [10]).”

    From A Sequential Multiple Assignment Randomized Trial (SMART) study of medication and CBT sequencing in the treatment of pediatric anxiety disorders (2021) · cites this paper as [10]

    The Abstract describes CAMS as a randomized trial comparing CBT, sertraline, their combination, and placebo, supporting the comparison and efficacy-study portions of the claim. The Methods describe enrollment sites across demographic and geographic locations, but our copy does not identify them as academic centers or establish a contrast with real-world community clinics. (LLM, conf=0.84)

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  • In the CAMS trial comparing CBT to medication, the patient sample was 78% Caucasian and 75% middle or upper class.

    “In the CAMS trial comparing CBT to medication, for example, the patient sample was 78% Caucasian and 75% middle or upper class [10].”

    From A Sequential Multiple Assignment Randomized Trial (SMART) study of medication and CBT sequencing in the treatment of pediatric anxiety disorders (2021) · cites this paper as [10]

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Authors
Kendall, P. C., Compton, S. N., Walkup, J. T., Birmaher, B., Albano, A. M., Sherrill, J., Ginsburg, G., Rynn, M., McCracken, J., Gosch, E., Keeton, C., Bergman, L., Sakolsky, D., Suveg, C., Iyengar, S., March, J., & Piacentini, J.
Affiliations
  • Temple University (US)
  • Duke University (US)
  • Johns Hopkins University (US)
  • University of Pittsburgh (US)
  • Columbia University Irving Medical Center (US)
  • National Institutes of Health (US)
  • University of California, Los Angeles (US)
  • Philadelphia College of Osteopathic Medicine (US)
  • University of Georgia (US)
Corresponding author
Kendall, Philip C.
ORCID
Venue
Journal of Anxiety Disorders
Publisher
Elsevier BV
Published
2010-04
Volume
24
Issue
3
Pages
360-365
ISSN
0887-6185 (ISSN-L)
DOI
10.1016/j.janxdis.2010.01.009
PMC
PMC2838990
OpenAlex
W2021623061
Cited by
369
References
72
Citations by year
2026: 4 · 2025: 13 · 2024: 25 · 2023: 17 · 2022: 24 · 2021: 22 · 2020: 27 · 2019: 28 · 2018: 18 · 2017: 26 · 2016: 32 · 2015: 27 · 2014: 39 · 2013: 24 · 2012: 25
FWCI
23.96
Type
journal article
Language
en
Open access
Licence
Locations
  • Journal of Anxiety Disorders (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
  • Digital Commons - PCOM (Philadelphia College of Osteopathic Medicine) (submittedVersion)
Funders
National Institute of Mental Health (U01MH063747, L40 MH072315, K23MH075843)
Topics
  • Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
Keywords
separation anxiety disorder, generalized anxiety disorder, social anxiety disorder, comorbidities, functional disability, anxiety symptom severity, psychopathology
MeSH terms
Adolescent, Anxiety Disorders, Anxiety, Separation, Child, Cross-Sectional Studies, Female, Humans, Male, Personality Assessment, Phobic Disorders, Psychometrics, United States, Comorbidity, Diagnostic and Statistical Manual of Mental Disorders

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