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MicroRNAs in neurodegenerative diseases and their therapeutic potential
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“Altered miRNA expression has been observed in diseases of the CNS, particularly in age-dependent neurodegenerative diseases, which suggests that the expression of miRNAs may contribute to neuropathogenesis [10,11].”
From miR-10b-5p expression in Huntington’s disease brain relates to age of onset and the extent of striatal involvement (2015) · cites this paper as [11]
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Silencing of microRNAs in vivo with ‘antagomirs’
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Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17
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Self-citationSequence-specific inhibition of small RNA function
Hutvágner, G., Simard, M. J., Mello, C. C., & Zamore, P. D. (2004) · PLoS Biology · doi:10.1371/journal.pbio.0020098 · Cited by 584
MicroRNA-21 targets Sprouty2 and promotes cellular outgrowths
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Metadata
- Authors
- Junn, E., & Mouradian, M. M.
- Venue
- Pharmacology & Therapeutics
- Publisher
- Elsevier BV
- Published
- 2012-02
- Volume
- 133
- Issue
- 2
- Pages
- 142-150
- ISSN
- 0163-7258
- PMC
- PMC3268953
- Cited by
- 186
- References
- 12
- Language
- en
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