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Cited by 530

The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.

Micro-RNA speciation in fetal, adult and Alzheimer's disease hippocampus

Lukiw, Walter J.·2007·NeuroReport
DOI 10.1097/wnr.0b013e3280148e8b
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Abstract

Micro-RNAs constitute a family of small noncoding ribonucleic acids that are posttranscriptional regulators of messenger RNA activity. Although micro-RNAs are known to be dynamically regulated during neural development, the role of micro-RNAs in brain aging and neurodegeneration is not known. This study examined micro-RNA abundance in the hippocampal region of fetal, adult and Alzheimer's disease brain. The data indicate that micro-RNAs encoding miR-9, miR-124a, miR-125b, miR-128, miR-132 and miR-219 are abundantly represented in fetal hippocampus, are differentially regulated in aged brain, and an alteration in specific micro-RNA complexity occurs in Alzheimer hippocampus. These data are consistent with the idea that altered micro-RNA-mediated processing of messenger RNA populations may contribute to atypical mRNA abundance and neural dysfunction in Alzheimer's disease brain.

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Crossref · 10.1097/wnr.0b013e3280148e8b

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Research works printed but not linked: 19

  1. Strauss, 2006, Nonrestrictive developmental regulation of microRNA gene expression, Mamm Genome, 17, 833, 10.1007/s00335-006-0025-7 · DOI
  2. Rogaev, 2005, Small RNAs in human brain development and disorders, Biochemistry, 70, 1404
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  8. Lukiw, 2004, Gene expression profiling in fetal, aged, and Alzheimer hippocampus: a continuum of stress-related signaling, Neurochem Res, 29, 1287, 10.1023/B:NERE.0000023615.89699.63 · DOI
  9. Lukiw, 2005, A role for docosahexaenoic acid-derived neuroprotectin D1 in neural cell survival and Alzheimer disease, J Clin Invest, 115, 2774, 10.1172/JCI25420 · DOI
  10. Jellinger, 2006, Clinicopathological analysis of dementia disorders in the elderly: an update, J Alzheimers Dis, 9, 61, 10.3233/JAD-2006-9S308 · DOI
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Metadata

Authors
Lukiw, W. J.
Venue
NeuroReport
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2007-02-12
Volume
18
Issue
3
Pages
297-300
ISSN
0959-4965
DOI
10.1097/wnr.0b013e3280148e8b
Cited by
530
References
6
Language
en

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