REM sleep deprivation affects extinction of cued but not contextual fear conditioning

Silvestri, Amy J.

doi:10.1016/j.physbeh.2004.11.011

Cited by 124Sleep and Wakefulness ResearchMemory and Neural MechanismsMemory Processes and Influences

REM sleep deprivation affects extinction of cued but not contextual fear conditioning

Silvestri, Amy J.·2005·Physiology & Behavior

DOI 10.1016/j.physbeh.2004.11.011

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Abstract

Previous research has demonstrated that rapid eye movement (REM), or paradoxical, sleep deprivation can interfere with the retention of certain types of learning tasks, particularly spatial learning. The present study investigated the effects of 6 h of REM sleep deprivation on the retention and extinction of both cued and contextual conditioning tasks in rats. Sleep-deprived animals showed normal retention of both types of conditioning tasks but retarded extinction of the cued task and a trend toward attenuated spontaneous recovery of the contextual task. The results provide further evidence for the involvement of REM sleep in learning and memory processes.

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Authors: Silvestri, A. J.
Affiliations: Indiana University – Purdue University Fort Wayne (US)
Corresponding author: Silvestri, Amy J.
Venue: Physiology & Behavior
Publisher: Elsevier BV
Published: 2005-03
Volume: 84
Issue: 3
Pages: 343-349
ISSN: 0031-9384 (ISSN-L)
DOI: 10.1016/j.physbeh.2004.11.011
OpenAlex: W2047413480
Cited by: 124
References: 48
Citations by year: 2026: 1 · 2025: 4 · 2024: 5 · 2023: 3 · 2022: 2 · 2021: 8 · 2020: 6 · 2019: 6 · 2018: 7 · 2017: 11 · 2016: 9 · 2015: 10 · 2014: 10 · 2013: 9 · 2012: 3
FWCI: 1.32
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Physiology & Behavior (publishedVersion)
PubMed (publishedVersion)
Funders: Purdue Research Foundation
U.S. Public Health Service
Topics: Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
Life Sciences › Neuroscience › Cognitive Neuroscience › Memory Processes and Influences
Keywords: REM sleep deprivation, fear conditioning, extinction, cued fear conditioning, contextual fear conditioning, memory retention, spontaneous recovery, learning and memory, rats
MeSH terms: Acoustic Stimulation, Animals, Association Learning, Conditioning, Classical, Cues, Extinction, Psychological, Fear, Male, Retention, Psychology, Sleep Deprivation, Freezing Reaction, Cataleptic, Rats

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REM sleep deprivation affects extinction of cued but not contextual fear conditioning

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