Attention deficits and hyperactivity–impulsivity: What have we learned, what next?
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The domains of self-regulation, self-control, executive function, inattention, and impulsivity cut across broad swathes of normal and abnormal development. Attention-deficit/hyperactivity disorder is a common syndrome that encompasses a portion of these domains. In the past 25 years research on attention-deficit/hyperactivity disorder has been characterized by dramatic advances in genetic, neural, and neuropsychological description of the syndrome as well as clarification of its multidimensional phenotypic structure. The limited clinical applicability of these research findings poses the primary challenge for the next generation. It is likely that clinical breakthroughs will require further refinement in describing heterogeneity or clinical/biological subgroups, renewed focus on the environment in the form of etiological events as well as psychosocial contexts of development, and integration of both with biological understanding.
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Comorbidity suggests that multiple causal pathways are involved.
“The presence of comorbidity, suggestive of multiple causal pathways (Nigg, 2013)”
From Data‐driven identification of subtypes of executive function across typical development, attention deficit hyperactivity disorder, and autism spectrum disorders (2020) · cites this paper as Nigg, 2013
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- Authors
- Nigg, J. T.
- Affiliations
- Oregon Health & Science University (US)
- Corresponding author
- Nigg, Joel T.
- ORCID
- Nigg, Joel T.
- Venue
- Development and Psychopathology
- Publisher
- Cambridge University Press (CUP)
- Published
- 2013-11
- Volume
- 25
- Issue
- 4pt2
- Pages
- 1489-1503
- ISSN
- 0954-5794 (ISSN-L)
- 1469-2198
- PMC
- PMC4373071
- OpenAlex
- W2140892189
- Cited by
- 51
- References
- 25
- Citations by year
- 2026: 3 · 2025: 2 · 2024: 5 · 2023: 1 · 2022: 4 · 2021: 4 · 2020: 4 · 2019: 2 · 2018: 4 · 2017: 6 · 2016: 9 · 2015: 5 · 2014: 2
- FWCI
- 0.73
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Development and Psychopathology (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Mental Health (R01MH059105)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
- Social Sciences › Psychology › Neuropsychology and Physiological Psychology › Developmental and Educational Neuropsychology
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Keywords
- attention deficit hyperactivity disorder, impulsivity, inattention, self-regulation, self-control, executive function, genetic research, neural mechanisms, neuropsychological assessment, phenotypic structure, heterogeneity, etiology, psychosocial environment, clinical translation
- MeSH terms
- Attention, Attention Deficit Disorder with Hyperactivity, Humans, Impulsive Behavior, Neuropsychological Tests, Research, Executive Function
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