High-Q Optical Sensors for Chemical and Biological Analysis

The Human Plasma Proteome

Anderson, N. L., & Anderson, N. G. (2002) · Molecular & Cellular Proteomics · doi:10.1074/mcp.r200007-mcp200 · Cited by 4,414

Ultra-high-Q toroid microcavity on a chip

Armani, D. K., Kippenberg, T. J., Spillane, S. M., & Vahala, K. J. (2003) · Nature · doi:10.1038/nature01371 · Cited by 2,214

Sensitive optical biosensors for unlabeled targets: A review

Fan, X., White, I. M., Shopova, S. I., Zhu, H., Suter, J. D., & Sun, Y. (2008) · Analytica Chimica Acta · doi:10.1016/j.aca.2008.05.022 · Cited by 2,187

Ultralow‐Fouling, Functionalizable, and Hydrolyzable Zwitterionic Materials and Their Derivatives for Biological Applications

Jiang, S., & Cao, Z. (2010) · Advanced Materials · doi:10.1002/adma.200901407 · Cited by 2,027

A hybrid plasmonic waveguide for subwavelength confinement and long-range propagation

Oulton, R. F., Sorger, V. J., Genov, D. A., Pile, D. F. P., & Zhang, X. (2008) · Nature Photonics · doi:10.1038/nphoton.2008.131 · Cited by 2,022

Guiding and confining light in void nanostructure

Almeida, V. R., Xu, Q., Barrios, C. A., & Lipson, M. (2004) · Optics Letters · doi:10.1364/ol.29.001209 · Cited by 1,732

Microring resonator channel dropping filters

Little, B. E., Chu, S. T., Haus, H. A., Foresi, J., & Laine, J.-P. (1997) · Journal of Lightwave Technology · doi:10.1109/50.588673 · Cited by 1,679

Whispering-gallery-mode biosensing: label-free detection down to single molecules

Vollmer, F., & Arnold, S. (2008) · Nature Methods · doi:10.1038/nmeth.1221 · Cited by 1,660

Dielectric Rectangular Waveguide and Directional Coupler for Integrated Optics

Marcatili, E. A. J. (1969) · Bell System Technical Journal · doi:10.1002/j.1538-7305.1969.tb01166.x · Cited by 1,578

Ultra-high-Q photonic double-heterostructure nanocavity

Song, B.-S., Noda, S., Asano, T., & Akahane, Y. (2005) · Nature Materials · doi:10.1038/nmat1320 · Cited by 1,341

On-chip single nanoparticle detection and sizing by mode splitting in an ultrahigh-Q microresonator

Zhu, J., Ozdemir, S. K., Xiao, Y.-F., Li, L., He, L., Chen, D.-R., & Yang, L. (2010) · Nature Photonics · doi:10.1038/nphoton.2009.237 · Cited by 1,198

Label-Free, Single-Molecule Detection with Optical Microcavities

Armani, A. M., Kulkarni, R. P., Fraser, S. E., Flagan, R. C., & Vahala, K. J. (2007) · Science · doi:10.1126/science.1145002 · Cited by 1,141

Recent progress in lasers on silicon

Liang, D., & Bowers, J. E. (2010) · Nature Photonics · doi:10.1038/nphoton.2010.167 · Cited by 1,122

Bioconjugate Techniques

(1996) · Elsevier eBooks · doi:10.1016/b978-0-12-342335-1.x5000-3 · Cited by 1,016

Making it stick: convection, reaction and diffusion in surface-based biosensors

Squires, T. M., Messinger, R. J., & Manalis, S. R. (2008) · Nature Biotechnology · doi:10.1038/nbt1388 · Cited by 986

Comparative advantages of mechanical biosensors

Arlett, J. L., Myers, E. B., & Roukes, M. L. (2011) · Nature Nanotechnology · doi:10.1038/nnano.2011.44 · Cited by 966

Integrated optofluidics: A new river of light

Monat, C., Domachuk, P., & Eggleton, B. J. (2007) · Nature Photonics · doi:10.1038/nphoton.2006.96 · Cited by 955

Observation of Critical Coupling in a Fiber Taper to a Silica-Microsphere Whispering-Gallery Mode System

Cai, M., Painter, O., & Vahala, K. J. (2000) · Physical Review Letters · doi:10.1103/physrevlett.85.74 · Cited by 912

Protein detection by optical shift of a resonant microcavity

Vollmer, F., Braun, D., Libchaber, A., Khoshsima, M., Teraoka, I., & Arnold, S. (2002) · Applied Physics Letters · doi:10.1063/1.1482797 · Cited by 903

Silicon-on-Insulator microring resonator for sensitive and label-free biosensing

De Vos, K., Bartolozzi, I., Schacht, E., Bienstman, P., & Baets, R. (2007) · Optics Express · doi:10.1364/oe.15.007610 · Cited by 839

Shift of whispering-gallery modes in microspheres by protein adsorption

Arnold, S., Khoshsima, M., Teraoka, I., Holler, S., & Vollmer, F. (2003) · Optics Letters · doi:10.1364/ol.28.000272 · Cited by 736

Integrated optical devices for lab‐on‐a‐chip biosensing applications

Estevez, M. C., Alvarez, M., & Lechuga, L. M. (2012) · Laser & Photonics Reviews · doi:10.1002/lpor.201100025 · Cited by 617

Detection Limits for Nanoscale Biosensors

Sheehan, P. E., & Whitman, L. J. (2005) · Nano Letters · doi:10.1021/nl050298x · Cited by 615

Ultra-compact Si-SiO2 microring resonator optical channel dropping filters

Little, B. E., Foresi, J. S., Steinmeyer, G., Thoen, E. R., Chu, S. T., Haus, H. A., Ippen, E. P., Kimerling, L. C., & Greene, W. (1998) · IEEE Photonics Technology Letters · doi:10.1109/68.662590 · Cited by 607

Magnetoelectric coupling in CoFe₂O₄/SrRuO₃/Pb(Zr[sub 0.52]Ti[sub 0.48])O₃ heteroepitaxial thin film structure

Zhang, J. X., Dai, J., Chow, C. K., Sun, C., Lo, V. C., & Chan, H. L. W. (2008) · Applied Physics Letters · Cited by 591

Label-Free Biosensor Arrays Based on Silicon Ring Resonators and High-Speed Optical Scanning Instrumentation

Iqbal, M., Gleeson, M. A., Spaugh, B., Tybor, F., Gunn, W. G., Hochberg, M., Baehr-Jones, T., Bailey, R. C., & Gunn, L. C. (2010) · IEEE Journal of Selected Topics in Quantum Electronics · doi:10.1109/jstqe.2009.2032510 · Cited by 551

Enhanced fluorescence emission from quantum dots on a photonic crystal surface

Ganesh, N., Zhang, W., Mathias, P. C., Chow, E., Soares, J. A. N. T., Malyarchuk, V., Smith, A. D., & Cunningham, B. T. (2007) · Nature Nanotechnology · doi:10.1038/nnano.2007.216 · Cited by 497

High-Q surface-plasmon-polariton whispering-gallery microcavity

Min, B., Ostby, E., Sorger, V., Ulin-Avila, E., Yang, L., Zhang, X., & Vahala, K. (2009) · Nature · doi:10.1038/nature07627 · Cited by 485

Biochemical sensors based on polymer microrings with sharp asymmetrical resonance

Chao, C.-Y., & Guo, L. J. (2003) · Applied Physics Letters · doi:10.1063/1.1605261 · Cited by 470

Attomole Microarray Detection of MicroRNAs by Nanoparticle-Amplified SPR Imaging Measurements of Surface Polyadenylation Reactions

Fang, S., Lee, H. J., Wark, A. W., & Corn, R. M. (2006) · Journal of the American Chemical Society · doi:10.1021/ja065223p · Cited by 450

Polymer microring resonators for biochemical sensing applications

Chao, C.-Y., Fung, W., & Guo, L. J. (2006) · IEEE Journal of Selected Topics in Quantum Electronics · doi:10.1109/jstqe.2005.862945 · Cited by 442

Label-Free Biosensing With a Slot-Waveguide-Based Ring Resonator in Silicon on Insulator

Claes, T., Gironès, J., Vos, K. D., Schacht, E. H., Baets, R., & Bienstman, P. (2009) · IEEE photonics journal · doi:10.1109/jphot.2009.2031596 · Cited by 435

The Molecular Biology Database Collection: 2003 update

Baxevanis, A. D. (2003) · Nucleic Acids Research · doi:10.1093/nar/gkg120 · Cited by 434

Experimental Realization of Subradiant, Superradiant, and Fano Resonances in Ring/Disk Plasmonic Nanocavities

Sonnefraud, Y., Verellen, N., Sobhani, H., Vandenbosch, G. A. E., Moshchalkov, V. V., Van Dorpe, P., Nordlander, P., & Maier, S. A. (2010) · ACS Nano · doi:10.1021/nn901580r · Cited by 411

Photonic crystal sensors: An overview

Nair, R. V., & Vijaya, R. (2010) · Progress in Quantum Electronics · doi:10.1016/j.pquantelec.2010.01.001 · Cited by 409

Sensitive disk resonator photonic biosensor

Boyd, R. W., & Heebner, J. E. (2001) · Applied Optics · doi:10.1364/ao.40.005742 · Cited by 399

Highly efficient low-voltage cathodoluminescence of LaF₃:Ln[sup 3+] (Ln=Eu[sup 3+], Ce[sup 3+], Tb[sup 3+]) spherical particles

Wang, Z., Chan, H. L. W., Li, H., & Hao, J. (2008) · Applied Physics Letters · Cited by 383

The Digital Revolution: A New Paradigm for Microfluidics

Abdelgawad, M., & Wheeler, A. R. (2009) · Advanced Materials · doi:10.1002/adma.200802244 · Cited by 382

Optical sensing of biomolecules using microring resonators

Yalcin, A., Popat, K. C., Aldridge, J. C., Desai, T. A., Hryniewicz, J., Chbouki, N., Little, B. E., King, O., Van, V., Chu, S., et al. (2006) · IEEE Journal of Selected Topics in Quantum Electronics · doi:10.1109/jstqe.2005.863003 · Cited by 377

Slot-waveguide biochemical sensor

Barrios, C. A., Gylfason, K. B., Sánchez, B., Griol, A., Sohlström, H., Holgado, M., & Casquel, R. (2007) · Optics Letters · doi:10.1364/ol.32.003080 · Cited by 374

Label-free biological and chemical sensors

Hunt, H. K., & Armani, A. M. (2010) · Nanoscale · doi:10.1039/c0nr00201a · Cited by 371

Silicon Photonics: An Introduction

Reed, G. T., & Knights, A. P. (2004) · Wiley eBooks · doi:10.1002/0470014180 · Cited by 366

Optical ring resonators for biochemical and chemical sensing

Sun, Y., & Fan, X. (2011) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-010-4237-z · Cited by 355

WGM microresonators: sensing, lasing and fundamental optics with microspheres

Ward, J., & Benson, O. (2011) · Laser & Photonics Reviews · doi:10.1002/lpor.201000025 · Cited by 345

On-chip gas detection in silicon optical microcavities

Robinson, J. T., Chen, L., & Lipson, M. (2008) · Optics Express · doi:10.1364/oe.16.004296 · Cited by 342

Label-Free Quantitation of a Cancer Biomarker in Complex Media Using Silicon Photonic Microring Resonators

Washburn, A. L., Gunn, L. C., & Bailey, R. C. (2009) · Analytical Chemistry · doi:10.1021/ac902006p · Cited by 318

High sensitivity nanoparticle detection using optical microcavities

Lu, T., Lee, H., Chen, T., Herchak, S., Kim, J.-H., Fraser, S. E., Flagan, R. C., & Vahala, K. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1017962108 · Cited by 308

Nanomanipulation Using Silicon Photonic Crystal Resonators

Mandal, S., Serey, X., & Erickson, D. (2010) · Nano Letters · doi:10.1021/nl9029225 · Cited by 301

Experimental characterization of a silicon photonic biosensor consisting of two cascaded ring resonators based on the Vernier-effect and introduction of a curve fitting method for an improved detection limit

Claes, T., Bogaerts, W., & Bienstman, P. (2010) · Optics Express · doi:10.1364/oe.18.022747 · Cited by 299

Multiplexed DNA Quantification by Spectroscopic Shift of Two Microsphere Cavities

Vollmer, F., Arnold, S., Braun, D., Teraoka, I., & Libchaber, A. (2003) · Biophysical Journal · doi:10.1016/s0006-3495(03)74625-6 · Cited by 276

A packaged optical slot-waveguide ring resonator sensor array for multiplex label-free assays in labs-on-chips

Carlborg, C. F., Gylfason, K. B., Kaźmierczak, A., Dortu, F., Bañuls Polo, M. J., Maquieira Catala, A., Kresbach, G. M., Sohlström, H., Moh, T., Vivien, L., et al. (2010) · Lab Chip · doi:10.1039/b914183a · Cited by 275

DNA-Encoded Antibody Libraries: A Unified Platform for Multiplexed Cell Sorting and Detection of Genes and Proteins

Bailey, R. C., Kwong, G. A., Radu, C. G., Witte, O. N., & Heath, J. R. (2007) · Journal of the American Chemical Society · doi:10.1021/ja065930i · Cited by 272

Excitation of resonances of microspheres on an optical fiber

Serpengüzel, A., Griffel, G., & Arnold, S. (1995) · Optics Letters · doi:10.1364/ol.20.000654 · Cited by 265

Analysis of biomolecule detection with optofluidic ring resonator sensors

Zhu, H., White, I. M., Suter, J. D., Dale, P. S., & Fan, X. (2007) · Optics Express · doi:10.1364/oe.15.009139 · Cited by 253

Label-free optical biosensing with slot-waveguides

Barrios, C. A., Bañuls, M. J., González-Pedro, V., Gylfason, K. B., Sánchez, B., Griol, A., Maquieira, A., Sohlström, H., Holgado, M., & Casquel, R. (2008) · Optics Letters · doi:10.1364/ol.33.000708 · Cited by 242

Silicon photonics: from a microresonator perspective

Feng, S., Lei, T., Chen, H., Cai, H., Luo, X., & Poon, A. W. (2012) · Laser & Photonics Reviews · doi:10.1002/lpor.201100020 · Cited by 237

Optical Manipulation with Planar Silicon Microring Resonators

Lin, S., Schonbrun, E., & Crozier, K. (2010) · Nano Letters · doi:10.1021/nl100501d · Cited by 236

Sensor based on an integrated optical microcavity

Krioukov, E., Klunder, D. J. W., Driessen, A., Greve, J., & Otto, C. (2002) · Optics Letters · doi:10.1364/ol.27.000512 · Cited by 231

Demonstration of an erbium-doped microdisk laser on a silicon chip

Kippenberg, T. J., Kalkman, J., Polman, A., & Vahala, K. J. (2006) · Physical Review A · doi:10.1103/physreva.74.051802 · Cited by 231

Quantitative analysis of the guest-concentration dependence of the mobility in a disordered fluorene-arylamine host-guest system in the guest-to-guest regime

Nicolai, H. T., Hof, A. J., Lu, M., Blom, P. W. M., de Vries, R. J., & Coehoorn, R. (2011) · Applied Physics Letters · doi:10.1063/1.3663563 · Cited by 230

Optical microbubble resonator

Sumetsky, M., Dulashko, Y., & Windeler, R. S. (2010) · Optics Letters · doi:10.1364/ol.35.000898 · Cited by 229

Quantitative, Label-Free Detection of Five Protein Biomarkers Using Multiplexed Arrays of Silicon Photonic Microring Resonators

Washburn, A. L., Luchansky, M. S., Bowman, A. L., & Bailey, R. C. (2010) · Analytical Chemistry · doi:10.1021/ac902451b · Cited by 227

A universal biosensing platform based on optical micro-ring resonators

Ramachandran, A., Wang, S., Clarke, J., Ja, S. J., Goad, D., Wald, L., Flood, E. M., Knobbe, E., Hryniewicz, J. V., Chu, S. T., et al. (2008) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2007.09.007 · Cited by 225

Protein-Resistant Poly(ethylene oxide)-Grafted Surfaces: Chain Density-Dependent Multiple Mechanisms of Action

Unsworth, L. D., Sheardown, H., & Brash, J. L. (2008) · Langmuir · doi:10.1021/la702310t · Cited by 211

Silicon photonic wire biosensor array for multiplexed real-time and label-free molecular detection

Densmore, A., Vachon, M., Xu, D.-X., Janz, S., Ma, R., Li, Y.-H., Lopinski, G., Delâge, A., Lapointe, J., Luebbert, C. C., et al. (2009) · Optics Letters · doi:10.1364/ol.34.003598 · Cited by 203

Silicon photonic temperature sensor employing a ring resonator manufactured using a standard CMOS process

Kim, G.-D., Lee, H.-S., Park, C.-H., Lee, S.-S., Lim, B. T., Bae, H. K., & Lee, W.-G. (2010) · Optics Express · doi:10.1364/oe.18.022215 · Cited by 198

Nucleic acid aptamers for biosensors and bio-analytical applications

Sefah, K., Phillips, J. A., Xiong, X., Meng, L., Van Simaeys, D., Chen, H., Martin, J., & Tan, W. (2009) · The Analyst · doi:10.1039/b905609m · Cited by 194

Detection of HER2 breast cancer biomarker using the opto-fluidic ring resonator biosensor

Gohring, J. T., Dale, P. S., & Fan, X. (2010) · Sensors and Actuators B: Chemical · doi:10.1016/j.snb.2010.01.067 · Cited by 192

Manipulation of photons at the surface of three-dimensional photonic crystals

Ishizaki, K., & Noda, S. (2009) · Nature · doi:10.1038/nature08190 · Cited by 192

Multiplexed Detection and Label‐Free Quantitation of MicroRNAs Using Arrays of Silicon Photonic Microring Resonators

Qavi, A. J., & Bailey, R. C. (2010) · Angewandte Chemie International Edition · doi:10.1002/anie.201001712 · Cited by 192

Photonics-on-a-chip: recent advances in integrated waveguides as enabling detection elements for real-world, lab-on-a-chip biosensing applications

Washburn, A. L., & Bailey, R. C. (2011) · The Analyst · doi:10.1039/c0an00449a · Cited by 182

High- Q Exterior Whispering-Gallery Modes in a Metal-Coated Microresonator

Xiao, Y., Zou, C., Li, B., Li, Y., Chun-Hua, D., Han, Z., & Gong, Q. (2010) · Physical Review Letters · doi:10.1103/physrevlett.105.153902 · Cited by 177

Electrically-pumped compact hybrid silicon microring lasers for optical interconnects

Liang, D., Fiorentino, M., Okumura, T., Chang, H.-H., Spencer, D. T., Kuo, Y.-H., Fang, A. W., Dai, D., Beausoleil, R. G., & Bowers, J. E. (2009) · Optics Express · doi:10.1364/oe.17.020355 · Cited by 174

An integrated optic ethanol vapor sensor based on a silicon-on-insulator microring resonator coated with a porous ZnO film

Yebo, N. A., Lommens, P., Hens, Z., & Baets, R. (2010) · Optics Express · doi:10.1364/oe.18.011859 · Cited by 172

Spiral-path high-sensitivity silicon photonic wire molecular sensor with temperature-independent response

Densmore, A., Xu, D.-X., Janz, S., Waldron, P., Mischki, T., Lopinski, G., Delâge, A., Lapointe, J., Cheben, P., Lamontagne, B., et al. (2008) · Optics Letters · doi:10.1364/ol.33.000596 · Cited by 170

Bioinspired optofluidic FRET lasers via DNA scaffolds

Sun, Y., Shopova, S. I., Wu, C.-S., Arnold, S., & Fan, X. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1003581107 · Cited by 162

High Quality Factor Metallodielectric Hybrid Plasmonic–Photonic Crystals

Yu, X., Shi, L., Han, D., Zi, J., & Braun, P. V. (2010) · Advanced Functional Materials · doi:10.1002/adfm.201000135 · Cited by 161

Resonant-enhanced evanescent-wave fluorescence biosensing with cylindrical optical cavities

Blair, S., & Chen, Y. (2001) · Applied Optics · doi:10.1364/ao.40.000570 · Cited by 159

A multiplexed optofluidic biomolecular sensor for low mass detection

Mandal, S., Goddard, J. M., & Erickson, D. (2009) · Lab on a Chip · doi:10.1039/b907826f · Cited by 159

Anti-DNA:RNA Antibodies and Silicon Photonic Microring Resonators: Increased Sensitivity for Multiplexed microRNA Detection

Qavi, A. J., Kindt, J. T., Gleeson, M. A., & Bailey, R. C. (2011) · Analytical Chemistry · doi:10.1021/ac201340s · Cited by 158

Cascade Signal Amplification Strategy for Subattomolar Protein Detection by Rolling Circle Amplification and Quantum Dots Tagging

Cheng, W., Feng, Y., Ding, L., Ju, H., & Yin, Y. (2010) · Analytical Chemistry · doi:10.1021/ac100144g · Cited by 157

Label-free quantitative DNA detection using the liquid core optical ring resonator

Suter, J. D., White, I. M., Zhu, H., Shi, H., Caldwell, C. W., & Fan, X. (2007) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2007.10.005 · Cited by 156

Fabrication and characterization of High Q polymer micro-ring resonator and its application as a sensitive ultrasonic detector

Ling, T., Chen, S., & Guo, L. J. (2011) · Optics Express · doi:10.1364/oe.19.000861 · Cited by 151

Cytokines and related receptor-mediated signaling pathways

Haddad, J. J. (2002) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(02)02287-8 · Cited by 146

Integrated Optical Sensor in a Digital Microfluidic Platform

Luan, L., Evans, R. D., Jokerst, N. M., et al. (2008) · IEEE Sensors Journal · doi:10.1109/jsen.2008.918717 · Cited by 144

Photonic Microresonator Research and Applications

Chremmos, I. D., Schwelb, O., & Uzunoglu, N. (2010) · Springer series in optical sciences/SPringer series in optical sciences · doi:10.1007/978-1-4419-1744-7 · Cited by 140

Real-Time Biomolecular Binding Detection Using a Sensitive Photonic Crystal Biosensor

Guo, Y., Ye, J. Y., Divin, C. J., Huang, B., Thomas, T. P., Baker, J. R., & Norris, T. B. (2010) · Analytical Chemistry · doi:10.1021/ac100576y · Cited by 139

Multiplexed Antibody Detection With an Array of Silicon-on-Insulator Microring Resonators

Vos, K. D., Gironès, J., Claes, T., Koninck, Y. D., Popelka, S., Schacht, E. H., Baets, R., & Bienstman, P. (2009) · IEEE photonics journal · doi:10.1109/jphot.2009.2035433 · Cited by 139

Label-free technologies for quantitative multiparameter biological analysis

Qavi, A. J., Washburn, A. L., Byeon, J.-Y., & Bailey, R. C. (2009) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-009-2637-8 · Cited by 138

Iterative In Situ Click Chemistry Creates Antibody‐like Protein‐Capture Agents

Agnew, H. D., Rohde, R. D., Millward, S. W., Nag, A., Yeo, W., Hein, J. E., Pitram, S. M., Tariq, A. A., Burns, V. M., Krom, R. J., et al. (2009) · Angewandte Chemie International Edition · doi:10.1002/anie.200900488 · Cited by 131

Optical Microcavity: Sensing down to Single Molecules and Atoms

Yoshie, T., Tang, L., & Su, S.-Y. (2011) · Sensors · doi:10.3390/s110201972 · Cited by 126

On-chip temperature compensation in an integrated slot-waveguide ring resonator refractive index sensor array

Gylfason, K. B., Carlborg, C. F., Kaźmierczak, A., Dortu, F., Sohlstrom, H. B., Vivien, L., Barrios, C. A., van der Wijngaart, W., & Stemme, G. (2010) · Optics Express · doi:10.1364/oe.18.003226 · Cited by 123

Silicon Photonic Microring Resonators for Quantitative Cytokine Detection and T-Cell Secretion Analysis

Luchansky, M. S., & Bailey, R. C. (2010) · Analytical Chemistry · doi:10.1021/ac902725q · Cited by 121

Immuno-Hybridization Chain Reaction for Enhancing Detection of Individual Cytokine-Secreting Human Peripheral Mononuclear Cells

Choi, J. H., Love, K. R., Gong, Y., Gierahn, T. M., & Love, J. C. (2011) · Analytical Chemistry · doi:10.1021/ac2013916 · Cited by 118

SOI optical microring resonator with poly(ethylene glycol) polymer brush for label-free biosensor applications

Vos, K. D., Gironès, J., Popelka, Š., Schacht, E. H., Baets, R., & Bienstman, P. (2009) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2009.01.009 · Cited by 116

Real-time cancellation of temperature induced resonance shifts in SOI wire waveguide ring resonator label-free biosensor arrays

Xu, D., Vachon, M. J., Densmore, A. S., Ma, R., Janz, S., Delage, A., Lapointe, J., Cheben, P., Schmid, J. H., Post, E., et al. (2010) · Optics Express · doi:10.1364/oe.18.022867 · Cited by 115

Characterization of the evanescent field profile and bound mass sensitivity of a label-free silicon photonic microring resonator biosensing platform

Luchansky, M. S., Washburn, A. L., Martin, T. A., Iqbal, M., Gunn, L. C., & Bailey, R. C. (2010) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2010.07.010 · Cited by 109

Single-frequency coupled asymmetric microcavity laser

Shang, L., Liu, L., & Xu, L. (2008) · Optics Letters · doi:10.1364/ol.33.001150 · Cited by 106

Label-free biosensor array based on silicon-on-insulator ring resonators addressed using a WDM approach

Xu, D., Vachon, M. J., Densmore, A. S., Ma, R., Delage, A., Janz, S., Lapointe, J., Li, Y., Lopinski, G. P., Zhang, D., et al. (2010) · Optics Letters · doi:10.1364/ol.35.002771 · Cited by 106

Bioconjugation Strategies for Microtoroidal Optical Resonators

Hunt, H. K., Soteropulos, C. E., & Armani, A. M. (2010) · Sensors · doi:10.3390/s101009317 · Cited by 100

Sensitive on-chip detection of a protein biomarker in human serum and plasma over an extended dynamic range using silicon photonic microring resonators and sub-micron beads

Luchansky, M. S., Washburn, A. L., McClellan, M. S., & Bailey, R. C. (2011) · Lab on a Chip · doi:10.1039/c1lc20231f · Cited by 98

A 96-well microplate incorporating a replica molded microfluidic network integrated with photonic crystal biosensors for high throughput kinetic biomolecular interaction analysis

Choi, C. J., & Cunningham, B. T. (2007) · Lab on a Chip · doi:10.1039/b618584c · Cited by 98

Label-free virus detection using silicon photonic microring resonators

McClellan, M. S., Domier, L. L., & Bailey, R. C. (2011) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2011.10.056 · Cited by 96

Application of Photonic Crystal Enhanced Fluorescence to a Cytokine Immunoassay

Mathias, P. C., Ganesh, N., & Cunningham, B. T. (2008) · Analytical Chemistry · doi:10.1021/ac801377k · Cited by 90

Athermal High-Index-Contrast Waveguide Design

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Kirk, J. T., Fridley, G. E., Chamberlain, J. W., Christensen, E., Hochberg, M. J., & Ratner, D. M. (2011) · Lab on a Chip · doi:10.1039/c0lc00313a · Cited by 82

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Ikeda, T., Hata, Y., Ninomiya, K.-I., Ikura, Y., Takeguchi, K., Aoyagi, S., Hirota, R., & Kuroda, A. (2008) · Analytical Biochemistry · doi:10.1016/j.ab.2008.11.001 · Cited by 78

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Microphotonic thermal imaging

Watts, M. R., Shaw, M. J., & Nielson, G. N. (2007) · Nature Photonics · doi:10.1038/nphoton.2007.219 · Cited by 55

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Suter, J. D., Howard, D. J., Shi, H., Caldwell, C. W., & Fan, X. (2010) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2010.08.050 · Cited by 54

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Beier, H. T., Coté, G. L., & Meissner, K. E. (2009) · Annals of Biomedical Engineering · doi:10.1007/s10439-009-9713-2 · Cited by 51

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Heeres, J. T., Kim, S.-H., Leslie, B. J., Lidstone, E. A., Cunningham, B. T., & Hergenrother, P. J. (2009) · Journal of the American Chemical Society · doi:10.1021/ja907066r · Cited by 47

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Liu, J., Sun, Y., Howard, D. J., Frye-Mason, G., Thompson, A. K., Ja, S.-J., Wang, S.-K., Bai, M., Taub, H., Almasri, M. F., et al. (2010) · Analytical Chemistry · doi:10.1021/ac902956d · Cited by 46

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Weiss, S. M., Rong, G., & Lawrie, J. L. (2008) · Physica E Low-dimensional Systems and Nanostructures · doi:10.1016/j.physe.2008.08.031 · Cited by 45

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Goddard, J. M., Mandal, S., & Erickson, D. (2009) · Integrated analytical systems · doi:10.1007/978-0-387-98063-8_16 · Cited by 3

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