Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid

Burton, K. (1956) · Biochemical Journal · doi:10.1042/bj0620315 · Cited by 14,090

Positional cloning of the mouse obese gene and its human homologue

Zhang, Y., Proenca, R., Maffei, M., Barone, M., Leopold, L., & Friedman, J. M. (1994) · Nature · doi:10.1038/372425a0 · Cited by 13,419

Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin Resistance

Hotamisligil, G. S., Shargill, N. S., & Spiegelman, B. M. (1993) · Science · doi:10.1126/science.7678183 · Cited by 7,518

Identification of the Cystic Fibrosis Gene: Cloning and Characterization of Complementary DNA

Riordan, J. R., Rommens, J. M., Kerem, B.-S., Alon, N., Rozmahel, R., Grzelczak, Z., Zielenski, J., Lok, S., Plavsic, N., Chou, J.-L., et al. (1989) · Science · doi:10.1126/science.2475911 · Cited by 7,418

A novel multigene family may encode odorant receptors: A molecular basis for odor recognition

Buck, L., & Axel, R. (1991) · Cell · doi:10.1016/0092-8674(91)90418-x · Cited by 4,987

Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

Shweiki, D., Itin, A., Soffer, D., & Keshet, E. (1992) · Nature · doi:10.1038/359843a0 · Cited by 4,617

Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes.

de Waal Malefyt, R., Abrams, J., Bennett, B., Figdor, C. G., & de Vries, J. E. (1991) · The Journal of experimental medicine · doi:10.1084/jem.174.5.1209 · Cited by 3,762

Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance.

Hotamisligil, G. S., Arner, P., Caro, J. F., Atkinson, R. L., & Spiegelman, B. M. (1995) · Journal of Clinical Investigation · doi:10.1172/jci117936 · Cited by 3,543

Identification and expression cloning of a leptin receptor, OB-R.

Tartaglia, L. A., Dembski, M., Weng, X., Deng, N., Culpepper, J., Devos, R., Richards, G. J., Campfield, L. A., Clark, F. T., Deeds, J., et al. (1995) · Cell · doi:10.1016/0092-8674(95)90151-5 · Cited by 3,496

The cloning of a family of genes that encode the melanocortin receptors

Mountjoy, K. G., Robbins, L. S., Mortrud, M. T., & Cone, R. D. (1992) · Science · doi:10.1126/science.1325670 · Cited by 1,635

Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas

Kawano, M., Hirano, T., Matsuda, T., Taga, T., Horii, Y., Iwato, K., Asaoku, H., Tang, B., Tanabe, O., Tanaka, H., et al. (1988) · Nature · doi:10.1038/332083a0 · Cited by 1,633

Amyloid β Protein Gene: cDNA, mRNA Distribution, and Genetic Linkage Near the Alzheimer Locus

Tanzi, R. E., Gusella, J. F., Watkins, P. C., Bruns, G. A. P., St George-Hyslop, P., Van Keuren, M. L., Patterson, D., Pagan, S., Kurnit, D. M., & Neve, R. L. (1987) · Science · doi:10.1126/science.2949367 · Cited by 1,611

A deletion in the bovine myostatin gene causes the double–muscled phenotype in cattle

Grobet, L., Royo Martin, L. J., Poncelet, D., Pirottin, D., Brouwers, B., Riquet, J., Schoeberlein, A., Dunner, S., Ménissier, F., Massabanda, J., et al. (1997) · Nature Genetics · doi:10.1038/ng0997-71 · Cited by 1,556

Two distinct estrogen-regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B

Kastner, P., Krust, A., Turcotte, B., Stropp, U., Tora, L., Gronemeyer, H., & Chambon, P. (1990) · The EMBO Journal · doi:10.1002/j.1460-2075.1990.tb08280.x · Cited by 1,534

Clinical Metagenomic Next-Generation Sequencing for Pathogen Detection

Gu, W., Miller, S., & Chiu, C. Y. (2019) · Annual Review of Pathology: Mechanisms of Disease · doi:10.1146/annurev-pathmechdis-012418-012751 · Cited by 1,458

The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing

Tischer, E., Mitchell, R., Hartman, T., Silva, M., Gospodarowicz, D., Fiddes, J. C., & Abraham, J. A. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)99049-6 · Cited by 1,476

Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential

Tsujii, M., Kawano, S., & DuBois, R. N. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.7.3336 · Cited by 1,398

Molecular cloning and expression of glycogen synthase kinase‐3/factor A.

Woodgett, J. R. (1990) · The EMBO Journal · doi:10.1002/j.1460-2075.1990.tb07419.x · Cited by 1,362

Charge density-dependent strength of hydration and biological structure

Collins, K. D. (1997) · Biophysical Journal · doi:10.1016/s0006-3495(97)78647-8 · Cited by 1,334

The HIV-1 Rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA

Malim, M. H., Hauber, J., Le, S.-Y., Maizel, J. V., & Cullen, B. R. (1989) · Nature · doi:10.1038/338254a0 · Cited by 1,280

Site-specific DNA recombination in mammalian cells by the Cre recombinase of bacteriophage P1.

Sauer, B., & Henderson, N. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.14.5166 · Cited by 1,213

Two genes encode distinct glutamate decarboxylases

Erlander, M. G., Tillakaratne, N. J. K., Feldblum, S., Patel, N., & Tobin, A. J. (1991) · Neuron · doi:10.1016/0896-6273(91)90077-d · Cited by 1,213

bcl-2-Immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation

McDonnell, T. J., Deane, N., Platt, F. M., Nunez, G., Jaeger, U., McKearn, J. P., & Korsmeyer, S. J. (1989) · Cell · doi:10.1016/0092-8674(89)90174-8 · Cited by 1,213

Natural resistance to infection with intracellular parasites: isolation of a candidate for Bcg

Vidal, S. M., Malo, D., Vogan, K., Skamene, E., & Gros, P. (1993) · Cell · doi:10.1016/0092-8674(93)90135-d · Cited by 1,104

Interleukin-6 (IL-6) Induces Insulin Resistance in 3T3-L1 Adipocytes and Is, Like IL-8 and Tumor Necrosis Factor-α, Overexpressed in Human Fat Cells from Insulin-resistant Subjects

Rotter, V., Nagaev, I., & Smith, U. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m301977200 · Cited by 1,062

A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1α regulates the VEGF expression and is potentially involved in lung and vascular development

Ema, M., Taya, S., Yokotani, N., Sogawa, K., Matsuda, Y., & Fujii-Kuriyama, Y. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.9.4273 · Cited by 1,016

The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogene

Klemsz, M. J., McKercher, S. R., Celada, A., Van Beveren, C., & Maki, R. A. (1990) · Cell · doi:10.1016/0092-8674(90)90219-5 · Cited by 954

Gene transfer and molecular cloning of the rat nerve growth factor receptor

Radeke, M. J., Misko, T. P., Hsu, C., Herzenberg, L. A., & Shooter, E. M. (1987) · Nature · doi:10.1038/325593a0 · Cited by 938

Expression cloning of a cocaine-and antidepressant-sensitive human noradrenaline transporter

Pacholczyk, T., Blakely, R. D., & Amara, S. G. (1991) · Nature · doi:10.1038/350350a0 · Cited by 933

BDNF mRNA is decreased in the hippocampus of individuals with Alzheimer's disease

Phillips, H. S., Hains, J. M., Armanini, M., Laramee, G. R., Johnson, S. A., & Winslow, J. W. (1991) · Neuron · doi:10.1016/0896-6273(91)90273-3 · Cited by 921

Glucagon-like peptide I stimulates insulin gene expression and increases cyclic AMP levels in a rat islet cell line.

Drucker, D. J., Philippe, J., Mojsov, S., Chick, W. L., & Habener, J. F. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.10.3434 · Cited by 903

Nonredundant roles of the mPer1 and mPer2 genes in the mammalian circadian clock.

Zheng, B., Albrecht, U., Kaasik, K., Sage, M., Lu, W., Vaishnav, S., Li, Q., Sun, Z. S., Eichele, G., Bradley, A., et al. (2001) · Cell · doi:10.1016/s0092-8674(01)00380-4 · Cited by 900

Advanced glycation endproducts interacting with their endothelial receptor induce expression of vascular cell adhesion molecule-1 (VCAM-1) in cultured human endothelial cells and in mice. A potential mechanism for the accelerated vasculopathy of diabetes.

Schmidt, A. M., Hori, O., Chen, J. X., Li, J. F., Crandall, J., Zhang, J., Cao, R., Yan, S. D., Brett, J., & Stern, D. (1995) · Journal of Clinical Investigation · doi:10.1172/jci118175 · Cited by 896

Expression of a set of growth-related immediate early genes in BALB/c 3T3 cells: coordinate regulation with c-fos or c-myc.

Lau, L. F., & Nathans, D. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.5.1182 · Cited by 856

Multiple promoters direct tissue-specific expression of the rat BDNF gene

Timmusk, T., Palm, K., Metsis, M., Reintam, T., Paalme, V., Saarma, M., & Persson, H. (1993) · Neuron · doi:10.1016/0896-6273(93)90335-o · Cited by 858

Cloning the gene for an inherited human disorder—chronic granulomatous disease—On the basis of its chromosomal location

Royer-Pokora, B., Kunkel, L. M., Monaco, A. P., Goff, S. C., Newburger, P. E., Baehner, R. L., Cole, F. S., Curnutte, J. T., & Orkin, S. H. (1986) · Nature · doi:10.1038/322032a0 · Cited by 833

Evolutionary studies of the nerve growth factor family reveal a novel member abundantly expressed in xenopus ovary

Hallböök, F., Ibáñez, C. F., & Persson, H. (1991) · Neuron · doi:10.1016/0896-6273(91)90180-8 · Cited by 834

Preproglucagon gene expression in pancreas and intestine diversifies at the level of post-translational processing

Mojsov, S., Heinrich, G., Wilson, I. B., Ravazzola, M., Orci, L., & Habener, J. F. (1986) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)67324-7 · Cited by 724

BDNF mRNA expression is increased in adult rat forebrain after limbic seizures: Temporal patterns of induction distinct from NGF

Isackson, P. J., Huntsman, M. M., Murray, K. D., & Gall, C. M. (1991) · Neuron · doi:10.1016/0896-6273(91)90234-q · Cited by 711

Obesity in Pregnancy Stimulates Macrophage Accumulation and Inflammation in the Placenta

Challier, J. C., Basu, S., Bintein, T., Minium, J., Hotmire, K., Catalano, P. M., & Hauguel-de Mouzon, S. (2008) · Placenta · doi:10.1016/j.placenta.2007.12.010 · Cited by 712

Differential phosphorylation of the gap junction protein connexin43 in junctional communication-competent and -deficient cell lines.

Musil, L. S., Cunningham, B. A., Edelman, G. M., & Goodenough, D. A. (1990) · The Journal of cell biology · doi:10.1083/jcb.111.5.2077 · Cited by 693

Hamster preproglucagon contains the sequence of glucagon and two related peptides

Bell, G. I., Santerre, R. F., & Mullenbach, G. T. (1983) · Nature · doi:10.1038/302716a0 · Cited by 649

Identification of breakpoints in t(8;21) acute myelogenous leukemia and isolation of a fusion transcript, AML1/ETO, with similarity to Drosophila segmentation gene, runt

Erickson, P., Gao, J., Chang, K., Look, T., Whisenant, E., Raimondi, S., Lasher, R., Trujillo, J., Rowley, J., & Drabkin, H. (1992) · Blood · doi:10.1182/blood.v80.7.1825.1825 · Cited by 631

Limbic Seizures Increase Neuronal Production of Messenger RNA for Nerve Growth Factor

Gall, C. M., & Isackson, P. J. (1989) · Science · doi:10.1126/science.2549634 · Cited by 616

Tissue-specific expression, developmental regulation, and genetic mapping of the gene encoding CCAAT/enhancer binding protein.

Birkenmeier, E. H., Gwynn, B., Howard, S., Jerry, J., Gordon, J. I., Landschulz, W. H., & McKnight, S. L. (1989) · Genes & Development · doi:10.1101/gad.3.8.1146 · Cited by 613

Large induction of keratinocyte growth factor expression in the dermis during wound healing

Werner, S., Peters, K. G., Longaker, M. T., Fuller-Pace, F., Banda, M. J., & Williams, L. T. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.15.6896 · Cited by 612

Cytokines and growth factors positively and negatively regulate interstitial collagen gene expression in human vascular smooth muscle cells.

Amento, E. P., Ehsani, N., Palmer, H., & Libby, P. (1991) · Arteriosclerosis and Thrombosis: A Journal of Vascular Biology · doi:10.1161/01.atv.11.5.1223 · Cited by 609

The Ity/Lsh/Bcg locus: natural resistance to infection with intracellular parasites is abrogated by disruption of the Nramp1 gene

Vidal, S., Tremblay, M. L., Govoni, G., Gauthier, S., Sebastiani, G., Malo, D., Skamene, E., Olivier, M., Jothy, S., & Gros, P. (1995) · The Journal of experimental medicine · doi:10.1084/jem.182.3.655 · Cited by 603

Induction of vascular endothelial growth factor expression by hypoxia and by glucose deficiency in multicell spheroids: implications for tumor angiogenesis.

Shweiki, D., Neeman, M., Itin, A., & Keshet, E. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.3.768 · Cited by 599

Identification of a set of genes expressed during the G0/G1 transition of cultured mouse cells.

Lau, L. F., & Nathans, D. (1985) · The EMBO Journal · doi:10.1002/j.1460-2075.1985.tb04057.x · Cited by 567

Transmembrane form of the kit ligand growth factor is determined by alternative splicing and is missing in the SId mutant

Flanagan, J. G., Chan, D. C., & Leder, P. (1991) · Cell · doi:10.1016/0092-8674(91)90326-t · Cited by 550

Elevated expression of transforming growth factor-beta and proteoglycan production in experimental glomerulonephritis. Possible role in expansion of the mesangial extracellular matrix.

Okuda, S., Languino, L. R., Ruoslahti, E., & Border, W. A. (1990) · Journal of Clinical Investigation · doi:10.1172/jci114731 · Cited by 546

Identification of a seven transmembrane helix receptor for corticotropin-releasing factor and sauvagine in mammalian brain

Chang, C.-P., Pearse, R. V., O'Connell, S., & Rosenfeld, M. G. (1993) · Neuron · doi:10.1016/0896-6273(93)90230-o · Cited by 537

Characterization and Functional Analysis of the Promoter of RAGE, the Receptor for Advanced Glycation End Products

Li, J., & Schmidt, A. M. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.26.16498 · Cited by 525

Corticotropin-releasing hormone deficiency reveals major fetal but not adult glucocorticoid need

Muglia, L., Jacobson, L., Dikkes, P., & Majzoub, J. A. (1995) · Nature · doi:10.1038/373427a0 · Cited by 524

Aromatase expression in endometriosis.

Noble, L. S., Simpson, E. R., Johns, A., & Bulun, S. E. (1996) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.81.1.8550748 · Cited by 566

The Drosophila learning and memory gene rutabaga encodes a - adenylyl cyclase

Levin, L. R., Han, P.-L., Hwang, P. M., Feinstein, P. G., Davis, R. L., & Reed, R. R. (1992) · Cell · doi:10.1016/0092-8674(92)90185-f · Cited by 517

Transcriptional regulation of the rat NAD(P)H:quinone reductase gene

Favreau, L. V., & Pickett, C. B. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(20)64358-7 · Cited by 497

Human epidermal Langerhans cells express the high affinity receptor for immunoglobulin E (Fc epsilon RI).

Bieber, T., de la Salle, H., Wollenberg, A., Hakimi, J., Chizzonite, R., Ring, J., Hanau, D., & de la Salle, C. (1992) · The Journal of experimental medicine · doi:10.1084/jem.175.5.1285 · Cited by 481

Progesterone Receptor Isoform A But Not B Is Expressed in Endometriosis1

Attia, G. R., Zeitoun, K., Edwards, D., Johns, A., Carr, B. R., & Bulun, S. E. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.85.8.6739 · Cited by 193

Cell adhesion protein receptors as targets for transforming growth factor-$beta; action

IGNOTZ, R. (1987) · Cell · doi:10.1016/0092-8674(87)90146-2 · Cited by 485

Detection of major bcr-abl gene expression at a very low level in blood cells of some healthy individuals

Biernaux, C., Loos, M., Sels, A., Huez, G., & Stryckmans, P. (1995) · Blood · doi:10.1182/blood.v86.8.3118.3118 · Cited by 485

Neuron-Specific Expression of Mutant Superoxide Dismutase 1 in Transgenic Mice Does Not Lead to Motor Impairment

Pramatarova, A., Laganière, J., Roussel, J., Brisebois, K., & Rouleau, G. A. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-10-03369.2001 · Cited by 482

Over-expression of facilitative glucose transporter genes in human cancer

Yamamoto, T., Seino, Y., Fukumoto, H., Koh, G., Yano, H., Inagaki, N., Yamada, Y., Inoue, K., Manabe, T., & Imura, H. (1990) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(90)91263-r · Cited by 465

Parathyroid hormone stimulates TRANCE and inhibits osteoprotegerin messenger ribonucleic acid expression in murine bone marrow cultures: correlation with osteoclast-like cell formation.

Lee, S.-K., & Lorenzo, J. A. (1999) · Endocrinology · doi:10.1210/endo.140.8.6887 · Cited by 464

Identification of androgen receptors in normal human osteoblast-like cells.

Colvard, D. S., Eriksen, E. F., Keeting, P. E., Wilson, E. M., Lubahn, D. B., French, F. S., Riggs, B. L., & Spelsberg, T. C. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.3.854 · Cited by 462

Tumor necrosis factor alpha functions in an autocrine manner in the induction of human immunodeficiency virus expression.

Poli, G., Kinter, A., Justement, J. S., Kehrl, J. H., Bressler, P., Stanley, S., & Fauci, A. S. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.2.782 · Cited by 457

Cloning and expression of rat cDNA encoding corticosteroid 11β-dehydrogenase

Agarwal, A. K., Monder, C., Eckstein, B., & White, P. C. (1989) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)47248-7 · Cited by 455

A new dexamethasone-induced gene of the leucine zipper family protects T lymphocytes from TCR/CD3-activated cell death

D'Adamio, F., Zollo, O., Moraca, R., Ayroldi, E., Bruscoli, S., Bartoli, A., Cannarile, L., Migliorati, G., & Riccardi, C. (1997) · Immunity · doi:10.1016/s1074-7613(00)80398-2 · Cited by 444

Diversity of murine gamma genes and expression in fetal and adult T lymphocytes

Heilig, J. S., & Tonegawa, S. (1986) · Nature · doi:10.1038/322836a0 · Cited by 448

A Novel Mutation in the Cystic Fibrosis Gene in Patients with Pulmonary Disease but Normal Sweat Chloride Concentrations

Highsmith, W. E., Burch, L. H., Zhou, Z., Olsen, J. C., Boat, T. E., Spock, A., Gorvoy, J. D., Quittell, L., Friedman, K. J., Silverman, L. M., et al. (1994) · New England Journal of Medicine · doi:10.1056/nejm199410133311503 · Cited by 441

Motheaten and viable motheaten mice have mutations in the haematopoietic cell phosphatase gene

Wo Tsui, H., Siminovitch, K. A., de Souza, L., & Tsui, F. W. L. (1993) · Nature Genetics · doi:10.1038/ng0693-124 · Cited by 441

Strengthened glycolysis under hypoxia supports tumor symbiosis and hexosamine biosynthesis in pancreatic adenocarcinoma

Guillaumond, F., Leca, J., Olivares, O., Lavaut, M.-N., Vidal, N., Berthezène, P., Dusetti, N. J., Loncle, C., Calvo, E., Turrini, O., et al. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1219555110 · Cited by 413

Phylogenomics reveals multiple losses of nitrogen-fixing root nodule symbiosis

Griesmann, M., Chang, Y., Liu, X., Song, Y., Haberer, G., Crook, M. B., Billault-Penneteau, B., Lauressergues, D., Keller, J., Imanishi, L., et al. (2018) · Science · doi:10.1126/science.aat1743 · Cited by 429

Sterol Resistance in CHO Cells Traced to Point Mutation in SREBP Cleavage–Activating Protein

Hua, X., Nohturfft, A., Goldstein, J. L., & Brown, M. S. (1996) · Cell · doi:10.1016/s0092-8674(00)81362-8 · Cited by 426

Interleukin 6 receptor antibody inhibits muscle atrophy and modulates proteolytic systems in interleukin 6 transgenic mice.

Tsujinaka, T., Fujita, J., Ebisui, C., Yano, M., Kominami, E., Suzuki, K., Tanaka, K., Katsume, A., Ohsugi, Y., Shiozaki, H., et al. (1996) · Journal of Clinical Investigation · doi:10.1172/jci118398 · Cited by 421

Erythroleukemia induction by Friend murine leukemia virus: insertional activation of a new member of the ets gene family, Fli-1, closely linked to c-ets-1.

Ben-David, Y., Giddens, E. B., Letwin, K., & Bernstein, A. (1991) · Genes & Development · doi:10.1101/gad.5.6.908 · Cited by 403

Cloning and Characterization of Subunits of the T-Cell Receptor and Murine Leukemia Virus Enhancer Core-Binding Factor

Wang, S., Wang, Q., Crute, B. E., Melnikova, I. N., Keller, S. R., & Speck, N. A. (1993) · Molecular and Cellular Biology · doi:10.1128/mcb.13.6.3324-3339.1993 · Cited by 435

Collagen-derived proline promotes pancreatic ductal adenocarcinoma cell survival under nutrient limited conditions

Olivares, O., Mayers, J. R., Gouirand, V., Torrence, M. E., Gicquel, T., Borge, L., Lac, S., Roques, J., Lavaut, M.-N., Berthezène, P., et al. (2017) · Nature Communications · doi:10.1038/ncomms16031 · Cited by 413

GFAP mRNA increases with age in rat and human brain

Nichols, N. R., Day, J. R., Laping, N. J., Johnson, S. A., & Finch, C. E. (1993) · Neurobiology of Aging · doi:10.1016/0197-4580(93)90100-p · Cited by 413

Fibrates downregulate apolipoprotein C-III expression independent of induction of peroxisomal acyl coenzyme A oxidase. A potential mechanism for the hypolipidemic action of fibrates.

Staels, B., Vu-Dac, N., Kosykh, V. A., Saladin, R., Fruchart, J. C., Dallongeville, J., & Auwerx, J. (1995) · Journal of Clinical Investigation · doi:10.1172/jci117717 · Cited by 410

vav, a novel human oncogene derived from a locus ubiquitously expressed in hematopoietic cells.

Katzav, S., Martin‐Zanca, D., & Barbacid, M. (1989) · The EMBO Journal · doi:10.1002/j.1460-2075.1989.tb08354.x · Cited by 410

Overexpression of Fibronectin Induced by Diabetes or High Glucose: Phenomenon With a Memory

Roy, S., Sala, R., Cagliero, E., & Lorenzi, M. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.1.404 · Cited by 409

Characterization of Two Genes Encoding Human Steroid 11β-Hydroxylase (P-45011β)

Mornet, E., Dupont, J., Vitek, A., & White, P. C. (1989) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)30030-4 · Cited by 405

Prostaglandin E2 Stimulates Aromatase Expression in Endometriosis-Derived Stromal Cells

Noble, L. S. (1997) · Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.82.2.600 · Cited by 301

Gestational Diabetes Induces Placental Genes for Chronic Stress and Inflammatory Pathways

Radaelli, T., Varastehpour, A., Catalano, P., & Hauguel-de Mouzon, S. (2003) · Diabetes · doi:10.2337/diabetes.52.12.2951 · Cited by 390

Fish Oil Feeding Decreases Mature Sterol Regulatory Element-binding Protein 1 (SREBP-1) by Down-regulation of SREBP-1c mRNA in Mouse Liver

Kim, H.-J., Takahashi, M., & Ezaki, O. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.36.25892 · Cited by 377

Apolipoprotein E mRNA is abundant in the brain and adrenals, as well as in the liver, and is present in other peripheral tissues of rats and marmosets.

Elshourbagy, N. A., Liao, W. S., Mahley, R. W., & Taylor, J. M. (1985) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.82.1.203 · Cited by 376

Involvement of a NF-kappa B-like transcription factor in the activation of the interleukin-6 gene by inflammatory lymphokines.

Shimizu, H., Mitomo, K., Watanabe, T., Okamoto, S., & Yamamoto, K. (1990) · Molecular and Cellular Biology · doi:10.1128/mcb.10.2.561 · Cited by 375

A Novel Orphan Receptor Specific for a Subset of Thyroid Hormone-Responsive Elements and Its Interaction with the Retinoid/Thyroid Hormone Receptor Subfamily

Apfel, R., Benbrook, D., Lernhardt, E., Ortiz, M. A., Salbert, G., & Pfahl, M. (1994) · Molecular and Cellular Biology · doi:10.1128/mcb.14.10.7025 · Cited by 372

Mapping of steroid 21-hydroxylase genes adjacent to complement component C4 genes in HLA, the major histocompatibility complex in man.

Carroll, M. C., Campbell, R. D., & Porter, R. R. (1985) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.82.2.521 · Cited by 370

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Colige, A., Sieron, A. L., Li, S.-W., Schwarze, U., Petty, E., Wertelecki, W., Wilcox, W., Krakow, D., Cohn, D. H., Reardon, W., et al. (1999) · The American Journal of Human Genetics · doi:10.1086/302504 · Cited by 370

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Zhang, P., Zhang, X., Iwama, A., Yu, C., Smith, K. A., Mueller, B. U., Narravula, S., Torbett, B. E., Orkin, S. H., & Tenen, D. G. (2000) · Blood · doi:10.1182/blood.v96.8.2641 · Cited by 368

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Feinberg, M. B., Baltimore, D., & Frankel, A. D. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.9.4045 · Cited by 365

Expression of p16INK4a and other cell cycle regulator and senescence associated genes in aging human kidney

Melk, A., Schmidt, B. M. W., Takeuchi, O., Sawitzki, B., Rayner, D. C., & Halloran, P. F. (2004) · Kidney International · doi:10.1111/j.1523-1755.2004.00438.x · Cited by 362

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Claffey, K. P., Wilkison, W. O., & Spiegelman, B. M. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)42003-0 · Cited by 357

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Strähle, U., Klock, G., & Schütz, G. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.22.7871 · Cited by 355

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Imataka, H., Sogawa, K., Yasumoto, K., Kikuchi, Y., Sasano, K., Kobayashi, A., Hayami, M., & Fujii‐Kuriyama, Y. (1992) · The EMBO Journal · doi:10.1002/j.1460-2075.1992.tb05451.x · Cited by 348

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