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Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus
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Peptidoglycan- and Lipoteichoic Acid-induced Cell Activation Is Mediated by Toll-like Receptor 2
Schwandner, R., Dziarski, R., Wesche, H., Rothe, M., & Kirschning, C. J. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.25.17406 · Cited by 1,704
A CONSERVED SIGNALING PATHWAY: The Drosophila Toll-Dorsal Pathway
Belvin, M. P., & Anderson, K. V. (1996) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.12.1.393 · Cited by 836
Cited by
Janeway, C. A., & Medzhitov, R. (2002) · Annual Review of Immunology · doi:10.1146/annurev.immunol.20.083001.084359 · Cited by 8,394
Akira, S., & Takeda, K. (2004) · Nature reviews. Immunology · doi:10.1038/nri1391 · Cited by 8,312
Takeda, K., Kaisho, T., & Akira, S. (2003) · Annual Review of Immunology · doi:10.1146/annurev.immunol.21.120601.141126 · Cited by 6,143
Toll-like receptors: critical proteins linking innate and acquired immunity
Akira, S., Takeda, K., & Kaisho, T. (2001) · Nature Immunology · doi:10.1038/90609 · Cited by 4,777
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Medzhitov, R. (2001) · Nature Reviews Immunology · doi:10.1038/35100529 · Cited by 4,308
LPS/TLR4 signal transduction pathway
Lu, Y.-C., Yeh, W.-C., & Ohashi, P. S. (2008) · Cytokine · doi:10.1016/j.cyto.2008.01.006 · Cited by 3,301
The history of toll-like receptors - redefining innate immunity
O'Neill, L. A. J., Golenbock, D., & Bowie, A. G. (2013) · Nature reviews. Immunology · doi:10.1038/nri3446 · Cited by 1,765
Self-citationInnate Immune Pattern Recognition: A Cell Biological Perspective
Brubaker, S. W., Bonham, K. S., Zanoni, I., & Kagan, J. C. (2015) · Annual Review of Immunology · doi:10.1146/annurev-immunol-032414-112240 · Cited by 1,475
Cell Type-Specific Involvement of RIG-I in Antiviral Response
Kato, H., Sato, S., Yoneyama, M., Yamamoto, M., Uematsu, S., Matsui, K., Tsujimura, T., Takeda, K., Fujita, T., Takeuchi, O., et al. (2005) · Immunity · doi:10.1016/j.immuni.2005.04.010 · Cited by 1,368
Imai, Y., Kuba, K., Neely, G. G., Yaghubian-Malhami, R., Perkmann, T., van Loo, G., Ermolaeva, M., Veldhuizen, R., Leung, Y. H. C., Wang, H., et al. (2008) · Cell · doi:10.1016/j.cell.2008.02.043 · Cited by 1,356
Signal transduction by the lipopolysaccharide receptor, Toll-like receptor-4
Pålsson‐McDermott, E. M., & O'Neill, L. A. J. (2004) · Immunology · doi:10.1111/j.1365-2567.2004.01976.x · Cited by 1,254
The IRF Family Transcription Factors in Immunity and Oncogenesis
Tamura, T., Yanai, H., Savitsky, D., & Taniguchi, T. (2008) · Annual Review of Immunology · doi:10.1146/annurev.immunol.26.021607.090400 · Cited by 1,259
Microglia initiate central nervous system innate and adaptive immune responses through multiple TLRs
Olson, J. K., & Miller, S. D. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.173.6.3916 · Cited by 1,215
Hayden, M. S., West, A. P., & Ghosh, S. (2006) · Oncogene · doi:10.1038/sj.onc.1209943 · Cited by 1,178
Type I and Type III Interferons – Induction, Signaling, Evasion, and Application to Combat COVID-19
Park, A., & Iwasaki, A. (2020) · Cell Host & Microbe · doi:10.1016/j.chom.2020.05.008 · Cited by 909
Vaure, C., & Liu, Y. (2014) · Frontiers in Immunology · doi:10.3389/fimmu.2014.00316 · Cited by 842
Beutler, B. A. (2009) · Blood · doi:10.1182/blood-2008-07-019307 · Cited by 840
The airway epithelium: soldier in the fight against respiratory viruses
Vareille, M., Kieninger, E., Edwards, M. R., & Regamey, N. (2011) · Clinical Microbiology Reviews · doi:10.1128/cmr.00014-10 · Cited by 655
Jensen, S., & Thomsen, A. R. (2012) · Journal of Virology · doi:10.1128/jvi.05738-11 · Cited by 604
Longitudinal multi-omics of host–microbe dynamics in prediabetes
Zhou, W., Sailani, M. R., Contrepois, K., Zhou, Y., Ahadi, S., Leopold, S. R., Zhang, M. J., Rao, V., Avina, M., Mishra, T., et al. (2019) · Nature · doi:10.1038/s41586-019-1236-x · Cited by 583
Lee, J. Y., Ye, J., Gao, Z., Youn, H. S., Lee, W. H., Zhao, L., Sizemore, N., & Hwang, D. H. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m305213200 · Cited by 524
The role of viruses in acute exacerbations of asthma
Jackson, D. J., & Johnston, S. L. (2010) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2010.04.021 · Cited by 351
Multiple Roles for Astrocytes as Effectors of Cytokines and Inflammatory Mediators
Sofroniew, M. V. (2014) · The Neuroscientist · doi:10.1177/1073858413504466 · Cited by 333
Toll-Like Receptor Pathways in Autoimmune Diseases
Chen, J.-Q., Szodoray, P., & Zeher, M. (2016) · Clinical Reviews in Allergy & Immunology · doi:10.1007/s12016-015-8473-z · Cited by 315
Microbial recognition by Toll-like receptors
Takeda, K., & Akira, S. (2004) · Journal of Dermatological Science · doi:10.1016/j.jdermsci.2003.10.002 · Cited by 285
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Murawski, M. R., Bowen, G. N., Cerny, A. M., Anderson, L. J., Haynes, L. M., Tripp, R. A., Kurt-Jones, E. A., & Finberg, R. W. (2009) · Journal of Virology · doi:10.1128/jvi.00671-08 · Cited by 279
Self-citationRespiratory Syncytial Virus Up-regulates TLR4 and Sensitizes Airway Epithelial Cells to Endotoxin
Monick, M. M., Yarovinsky, T. O., Powers, L. S., Butler, N. S., Carter, A. B., Gudmundsson, G., & Hunninghake, G. W. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m308093200 · Cited by 276
Paudel, Y. N., Angelopoulou, E., Piperi, C., Othman, I., Aamir, K., & Shaikh, M. F. (2020) · Cells · doi:10.3390/cells9020383 · Cited by 257
Graham, B. S. (2011) · Immunological Reviews · doi:10.1111/j.1600-065x.2010.00972.x · Cited by 239
Haeberle, H. A., Takizawa, R., Casola, A., Brasier, A. R., Dieterich, H., van Rooijen, N., Gatalica, Z., & Garofalo, R. P. (2002) · The Journal of Infectious Diseases · doi:10.1086/344644 · Cited by 237
Fairweather, D., Yusung, S., Frisancho, S., Barrett, M., Gatewood, S., Steele, R., & Rose, N. R. (2003) · The Journal of Immunology · doi:10.4049/jimmunol.170.9.4731 · Cited by 229
Toll-Like Receptors: Regulators of the Immune Response in the Human Gut
Hug, H., Mohajeri, M., & La Fata, G. (2018) · Nutrients · doi:10.3390/nu10020203 · Cited by 217
Viruses as adjuvants for autoimmunity: evidence from Coxsackievirus‐induced myocarditis
Fairweather, D., Frisancho‐Kiss, S., & Rose, N. R. (2005) · Reviews in Medical Virology · doi:10.1002/rmv.445 · Cited by 155
TLR4 Polymorphisms Mediate Impaired Responses to Respiratory Syncytial Virus and Lipopolysaccharide
Tulic, M. K., Hurrelbrink, R. J., Prêle, C. M., Laing, I. A., Upham, J. W., Le Souef, P., Sly, P. D., & Holt, P. G. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.179.1.132 · Cited by 140
Toll like receptors and viruses
Finberg, R. W., Wang, J. P., & Kurt‐Jones, E. A. (2007) · Reviews in Medical Virology · doi:10.1002/rmv.525 · Cited by 90
Self-citationProphylactic and therapeutic implications of toll-like receptor ligands
Hedayat, M., Takeda, K., & Rezaei, N. (2012) · Medicinal Research Reviews · doi:10.1002/med.20214 · Cited by 76
Candida albicans mannoprotein influences the biological function of dendritic cells
Pietrella, D., Bistoni, G., Corbucci, C., Perito, S., & Vecchiarelli, A. (2006) · Cellular Microbiology · doi:10.1111/j.1462-5822.2005.00651.x · Cited by 75
Finding a Toll on the Route: The Fate of Osteoclast Progenitors After Toll-Like Receptor Activation
Souza, P. P. C., & Lerner, U. H. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.01663 · Cited by 67
“The cell response to viruses is manly triggered by the recognition of viral components by the intracellular receptors TLR3, 7, and 8 (53), although it is reported that TLR4 can also recognize viral proteins (54).”
BackgroundBellinghausen, C., Gulraiz, F., Heinzmann, A. C. A., Dentener, M. A., Savelkoul, P. H. M., Wouters, E. F., Rohde, G. G., & Stassen, F. R. (2016) · Respiratory Research · doi:10.1186/s12931-016-0382-z · Cited by 71
Miron, J., Picard, C., Frappier, J., Dea, D., Théroux, L., & Poirier, J. (2018) · Journal of Alzheimer's Disease · doi:10.3233/jad-171160 · Cited by 65
Satoh, M., Nakamura, M., Akatsu, T., Shimoda, Y., Segawa, I., & Hiramori, K. (2004) · Laboratory Investigation · doi:10.1038/labinvest.3700031 · Cited by 53
The Immune Response to Respiratory Syncytial Virus Infection: Friend or Foe?
Welliver, R. C. (2008) · Clinical Reviews in Allergy & Immunology · doi:10.1007/s12016-007-8033-2 · Cited by 46
Healthy but not RSV-infected lung epithelial cells profoundly inhibit T cell activation
Wang, H., Su, Z., & Schwarze, J. (2009) · Thorax · doi:10.1136/thx.2007.094870 · Cited by 39
van Tongeren, J., Röschmann, K. I. L., Reinartz, S. M., Luiten, S., Fokkens, W. J., de Jong, E. C., & van Drunen, C. M. (2015) · Clinical and Translational Allergy · doi:10.1186/s13601-015-0086-3 · Cited by 30
Oladunni, F. S., Sarkar, S., Reedy, S., Balasuriya, U. B. R., Horohov, D. W., & Chambers, T. M. (2019) · Journal of Virology · doi:10.1128/jvi.01342-19 · Cited by 18
Jain, A., Bruno, K. A., Matsumori, A., Cooper, L. T., Yamani, M., & Fairweather, D. (2022) · Comprehensive Pharmacology · doi:10.1016/b978-0-12-820472-6.00091-8 · Cited by 1
Metadata
- Authors
- Kurt-Jones, E. A., Popova, L., Kwinn, L., Haynes, L. M., Jones, L. P., Tripp, R. A., Walsh, E. E., Freeman, M. W., Golenbock, D. T., Anderson, L. J., & Finberg, R. W.
- Venue
- Nature Immunology
- Published
- 2000-11
- Volume
- 1
- Issue
- 5
- Pages
- 398-401
- ISSN
- 1529-2908 (ISSN-L)
- 1529-2916
- OpenAlex
- W1499978168
- Cited by
- 1,683
- References
- 2
- FWCI
- 21.38
- Type
- journal article
- Language
- en
- Open access
- closed
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