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Cited by 300

The DOI matches its Crossref record; 99 of the 99 references it cites were found in a registry or an index.

Role of innate cytokines in mycobacterial infection

Open access
Cooper, A M, Mayer-Barber, K D, Sher, A·2011·Mucosal Immunology

Abstract

Cells of the innate immune system produce cytokines and lipid mediators that strongly influence the outcome of mycobacterial infection. In the case of Mycobacterium tuberculosis, the lung is a critical site for this interaction. Here, we review current information on the role of the major innate cytokine pathways both in controlling initial infection as well as in promoting and maintaining adaptive T-cell responses that mediate host resistance or immunopathology. Understanding this important feature of the host–pathogen interaction can provide major insights into the mechanisms of virulence and can lead to new approaches for immunological intervention in tuberculosis and other mycobacterial diseases.

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Crossref · 10.1038/mi.2011.13

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Metadata

Authors
Cooper, A. M., Mayer-Barber, K. D., & Sher, A.
Venue
Mucosal Immunology
Publisher
Elsevier BV
Published
2011-05
Volume
4
Issue
3
Pages
252-260
ISSN
1933-0219 (ISSN-L)
OpenAlex
W2087187487
Cited by
300
References
99
FWCI
16.02
Type
journal article
Language
en
Open access
bronze

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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