Coordination of circadian timing in mammals

Phototransduction by retinal ganglion cells that set the circadian clock

Berson, D. M., Dunn, F. A., & Takao, M. (2002) · Science · doi:10.1126/science.1067262 · Cited by 3,629

Melanopsin-Containing Retinal Ganglion Cells: Architecture, Projections, and Intrinsic Photosensitivity

Hattar, S., Liao, H.-W., Takao, M., Berson, D. M., & Yau, K.-W. (2002) · Science · doi:10.1126/science.1069609 · Cited by 2,734

Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus

Damiola, F., Le Minh, N., Preitner, N., Kornmann, B., Fleury-Olela, F., & Schibler, U. (2000) · Genes & Development · doi:10.1101/gad.183500 · Cited by 2,394

Coordinated Transcription of Key Pathways in the Mouse by the Circadian Clock

Panda, S., Antoch, M. P., Miller, B. H., Su, A. I., Schook, A. C., Straume, M., Schultz, P. G., Kay, S. A., Takahashi, J. S., & Hogenesch, J. B. (2002) · Cell · doi:10.1016/s0092-8674(02)00722-5 · Cited by 2,310

The Orphan Nuclear Receptor REV-ERBα Controls Circadian Transcription within the Positive Limb of the Mammalian Circadian Oscillator

Preitner, N., Damiola, F., Luis-Lopez-Molina, Zakany, J., Duboule, D., Albrecht, U., & Schibler, U. (2002) · Cell · doi:10.1016/s0092-8674(02)00825-5 · Cited by 2,198

Role of the CLOCK Protein in the Mammalian Circadian Mechanism

Gekakis, N., Staknis, D., Nguyen, H. B., Davis, F. C., Wilsbacher, L. D., King, D. P., Takahashi, J. S., & Weitz, C. J. (1998) · Science · doi:10.1126/science.280.5369.1564 · Cited by 2,035

A Serum Shock Induces Circadian Gene Expression in Mammalian Tissue Culture Cells

Balsalobre, A., Damiola, F., & Schibler, U. (1998) · Cell · doi:10.1016/s0092-8674(00)81199-x · Cited by 2,001

Resetting central and peripheral circadian oscillators in transgenic rats

Yamazaki, S., Numano, R., Abe, M., Hida, A., Takahashi, R.-I., Ueda, M., Block, G. D., Sakaki, Y., Menaker, M., & Tei, H. (2000) · Science · doi:10.1126/science.288.5466.682 · Cited by 1,907

Resetting of circadian time in peripheral tissues by glucocorticoid signaling

Balsalobre, A., Brown, S. A., Marcacci, L., Tronche, F., Kellendonk, C., Reichardt, H. M., Schütz, G., & Schibler, U. (2000) · Science · doi:10.1126/science.289.5488.2344 · Cited by 1,859

Entrainment of the circadian clock in the liver by feeding

Stokkan, K.-A., Yamazaki, S., Tei, H., Sakaki, Y., & Menaker, M. (2001) · Science · doi:10.1126/science.291.5503.490 · Cited by 1,800

Effects of Chronic Jet Lag on Tumor Progression in Mice

Filipski, E., Delaunay, F., King, V. M., Wu, M., Claustrat, B., Gréchez‐Cassiau, A., Guettier, C., Hastings, M. H., & Lévi, F. (2004) · Cancer Research · doi:10.1158/0008-5472.can-04-0674 · Cited by 424

Convergence between bone and energy homeostases: Leptin regulation of bone mass

Karsenty, G. (2006) · Cell Metabolism · doi:10.1016/j.cmet.2006.10.008 · Cited by 423

Considerations of circadian impact for defining ‘shift work’ in cancer studies: IARC Working Group Report

Stevens, R. G., Hansen, J., Costa, G., Haus, E., Kauppinen, T., Aronson, K. J., Castaño-Vinyals, G., Davis, S., Frings-Dresen, M. H. W., Fritschi, L., et al. (2011) · Occupational and Environmental Medicine · doi:10.1136/oem.2009.053512 · Cited by 421

The HPA – Immune Axis and the Immunomodulatory Actions of Glucocorticoids in the Brain

Bellavance, M.-A., & Rivest, S. (2014) · Frontiers in Immunology · doi:10.3389/fimmu.2014.00136 · Cited by 419

cAMP-dependent signaling as a core component of the mammalian circadian pacemaker

O'Neill, J. S., Maywood, E. S., Chesham, J. E., Takahashi, J. S., & Hastings, M. H. (2008) · Science · doi:10.1126/science.1152506 · Cited by 418

Homeostatic, circadian, and emotional regulation of sleep

Saper, C. B., Cano, G., & Scammell, T. E. (2005) · The Journal of Comparative Neurology · doi:10.1002/cne.20770 · Cited by 417

Later circadian timing of food intake is associated with increased body fat

McHill, A. W., Phillips, A. J., Czeisler, C. A., Keating, L., Yee, K., Barger, L. K., Garaulet, M., Scheer, F. A., & Klerman, E. B. (2017) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.117.161588 · Cited by 414

Modeling of a Human Circadian Mutation Yields Insights into Clock Regulation by PER2

Xu, Y., Toh, K. L., Jones, C. R., Shin, J., Fu, Y., & Ptáček, L. J. (2007) · Cell · doi:10.1016/j.cell.2006.11.043 · Cited by 409

Circadian variation of blood pressure and the vascular response to asynchronous stress

Curtis, A. M., Cheng, Y., Kapoor, S. C., Reilly, D. F., Price, T. S., & FitzGerald, G. A. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0611680104 · Cited by 408

A survey of molecular details in the human pineal gland in the light of phylogeny, structure, function and chronobiological diseases

Stehle, J. H., Saade, A., Rawashdeh, O., Ackermann, K., Jilg, A., Sebesteny, T., & Maronde, E. (2011) · Journal of Pineal Research · doi:10.1111/j.1600-079x.2011.00856.x · Cited by 405

Redundant Function of REV-ERBα and β and Non-Essential Role for Bmal1 Cycling in Transcriptional Regulation of Intracellular Circadian Rhythms

Liu, A. C., Tran, H. G., Zhang, E. E., Priest, A. A., Welsh, D. K., & Kay, S. A. (2008) · PLoS Genetics · doi:10.1371/journal.pgen.1000023 · Cited by 406

Disintegration of the sleep-wake cycle and circadian timing in Huntington's disease

Morton, A. J., Wood, N. I., Hastings, M. H., Hurelbrink, C., Barker, R. A., & Maywood, E. S. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.3842-04.2005 · Cited by 403

Insect Cryptochromes: Gene Duplication and Loss Define Diverse Ways to Construct Insect Circadian Clocks

Yuan, Q., Metterville, D. R., Briscoe, A. D., & Reppert, S. M. (2007) · Molecular Biology and Evolution · doi:10.1093/molbev/msm011 · Cited by 401

Biological Clocks and Shift Work: Circadian Dysregulation and Potential Long-term Effects

Haus, E. L., & Smolensky, M. H. (2006) · Cancer Causes & Control · doi:10.1007/s10552-005-9015-4 · Cited by 399

Do Corticosteroids Damage the Brain?

Herbert, J., Goodyer, I. M., Grossman, A. B., Hastings, M. H., de Kloet, E. R., Lightman, S. L., LUPIEN, S. J., Roozendaal, B., & Seckl, J. R. (2006) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2006.01429.x · Cited by 398

The mammalian circadian timing system: from gene expression to physiology

Gachon, F., Nagoshi, E., Brown, S., Ripperger, J. A., & Schibler, U. (2004) · Chromosoma · doi:10.1007/s00412-004-0296-2 · Cited by 398

Fasting of mice: a review

Jensen, T. M., Kiersgaard, M. K., Sørensen, D. B., & Mikkelsen, L. (2013) · Laboratory Animals · doi:10.1177/0023677213501659 · Cited by 396

Integration of microRNA miR-122 in hepatic circadian gene expressionPreprint

Gatfield, D., Martelot, G. L., Vejnar, C. E., Gerlach, D., Schaad, O., Fleury-Olela, F., Ruskeepää, A., Orešič, M., Esau, C., Zdobnov, E. M., et al. (2009) · Genes & Development · doi:10.1101/gad.1781009 · Cited by 393

The crucial role of pulsatile activity of the HPA axis for continuous dynamic equilibration

Lightman, S. L., & Conway-Campbell, B. L. (2010) · Nature Reviews Neuroscience · doi:10.1038/nrn2914 · Cited by 390

mTOR in Brain Physiology and Pathologies

Bockaert, J., & Marin, P. (2015) · Physiological Reviews · doi:10.1152/physrev.00038.2014 · Cited by 381

Feedback repression is required for mammalian circadian clock function

Sato, T. K., Yamada, R. G., Ukai, H., Baggs, J. E., Miraglia, L. J., Kobayashi, T., Welsh, D. K., Kay, S. A., Ueda, H. R., & Hogenesch, J. B. (2006) · Nature Genetics · doi:10.1038/ng1745 · Cited by 377

Setting Clock Speed in Mammals: The CK1ɛ tau Mutation in Mice Accelerates Circadian Pacemakers by Selectively Destabilizing PERIOD Proteins

Meng, Q., Logunova, L., Maywood, E. S., Gallego, M., Lebiecki, J., Brown, T. M., Sládek, M., Semikhodskii, A. G., Glossop, N. R. J., Piggins, H. D., et al. (2008) · Neuron · doi:10.1016/j.neuron.2008.01.019 · Cited by 375

REV-ERBα integrates colon clock with experimental colitis through regulation of NF-κB/NLRP3 axis

Wang, S., Lin, Y., Yuan, X., Li, F., Guo, L., & Wu, B. (2018) · Nature Communications · doi:10.1038/s41467-018-06568-5 · Cited by 363

Timed high-fat diet resets circadian metabolism and prevents obesity

Sherman, H., Genzer, Y., Cohen, R., Chapnik, N., Madar, Z., & Froy, O. (2012) · The FASEB Journal · doi:10.1096/fj.12-208868 · Cited by 360

Reciprocal Regulation of Brain and Muscle Arnt-Like Protein 1 and Peroxisome Proliferator-Activated Receptor α Defines a Novel Positive Feedback Loop in the Rodent Liver Circadian Clock

Canaple, L., Rambaud, J., Dkhissi‐Benyahya, O., Rayet, B., Tan, N. S., Michalik, L., Delaunay, F., Wahli, W., & Laudet, V. (2006) · Molecular Endocrinology · doi:10.1210/me.2006-0052 · Cited by 359

Challenging the omnipotence of the suprachiasmatic timekeeper: are circadian oscillators present throughout the mammalian brain?

Guilding, C., & Piggins, H. D. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05581.x · Cited by 356

Deficient of a Clock Gene, Brain and Muscle Arnt-Like Protein-1 (BMAL1), Induces Dyslipidemia and Ectopic Fat Formation

Shimba, S., Ogawa, T., Hitosugi, S., Ichihashi, Y., Nakadaira, Y., Kobayashi, M., Tezuka, M., Kosuge, Y., Ishige, K., Ito, Y., et al. (2011) · PLoS ONE · doi:10.1371/journal.pone.0025231 · Cited by 353

A detailed predictive model of the mammalian circadian clock

Forger, D. B., & Peskin, C. S. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2036281100 · Cited by 353

Crystal Structure of the Heterodimeric CLOCK:BMAL1 Transcriptional Activator Complex

Huang, N. N., Chelliah, Y., Shan, Y., Taylor, C. A., Yoo, S. H., Partch, C. L., Green, C. B., Zhang, H., & Takahashi, J. S. (2012) · Science · doi:10.1126/science.1222804 · Cited by 354

Sleep and circadian rhythms: key components in the regulation of energy metabolism

Laposky, A. D., Bass, J., Kohsaka, A., & Turek, F. W. (2008) · FEBS Letters · doi:10.1016/j.febslet.2007.06.079 · Cited by 351

Living by the clock: The circadian pacemaker in older people

Hofman, M. A., & Swaab, D. F. (2005) · Ageing Research Reviews · doi:10.1016/j.arr.2005.07.001 · Cited by 350

Circadian clocks, clock networks, arylalkylamine N-acetyltransferase, and melatonin in the retina

Iuvone, P. M., Tosini, G., Pozdeyev, N. V., Haque, R., Klein, D. C., & Chaurasia, S. S. (2005) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2005.01.003 · Cited by 349

Coupling governs entrainment range of circadian clocks

Abraham, U., Granada, A. E., Westermark, P. O., Heine, M., Kramer, A., & Herzel, H. (2010) · Molecular Systems Biology · doi:10.1038/msb.2010.92 · Cited by 349

The Cryptochrome Blue Light Receptors

Yu, X., Liu, H., Klejnot, J., & Lin, C. (2010) · The Arabidopsis Book · doi:10.1199/tab.0135 · Cited by 346

Systems-Level Dissection of the Cell-Cycle Oscillator: Bypassing Positive Feedback Produces Damped Oscillations

Pomerening, J. R., Kim, S. Y., & Ferrell, J. E. (2005) · Cell · doi:10.1016/j.cell.2005.06.016 · Cited by 345

Circadian rhythms govern cardiac repolarization and arrhythmogenesis

Jeyaraj, D., Haldar, S. M., Wan, X., McCauley, M. D., Ripperger, J. A., Hu, K., Lu, Y., Eapen, B. L., Sharma, N., Ficker, E., et al. (2012) · Nature · doi:10.1038/nature10852 · Cited by 343

Poly(ADP-ribose) polymerase 1 participates in the phase entrainment of circadian clocks to feeding

Asher, G., Reinke, H., Altmeyer, M., Gutierrez-Arcelus, M., Hottiger, M. O., & Schibler, U. (2010) · Cell · doi:10.1016/j.cell.2010.08.016 · Cited by 340

A GABAergic Mechanism Is Necessary for Coupling Dissociable Ventral and Dorsal Regional Oscillators within the Circadian Clock

Albus, H., Vansteensel, M. J., Michel, S. H., Block, G. D., & Meijer, J. H. (2005) · Current Biology · doi:10.1016/j.cub.2005.03.051 · Cited by 335

The circadian clock regulates rhythmic activation of the NRF2/glutathione-mediated antioxidant defense pathway to modulate pulmonary fibrosisPreprint

Pekovic‐Vaughan, V., Gibbs, J. E., Yoshitane, H., Yang, N., Pathiranage, D. R., Guo, B., Sagami, A., Taguchi, K., Bechtold, D. A., Loudon, A. S. I., et al. (2014) · Genes & Development · doi:10.1101/gad.237081.113 · Cited by 326

Cryptochromes Define a Novel Circadian Clock Mechanism in Monarch Butterflies That May Underlie Sun Compass Navigation

Zhu, H., Šauman, I., Yuan, Q., Casselman, A. L., Emery-Le, M., Emery, P., & Reppert, S. M. (2008) · PLoS Biology · doi:10.1371/journal.pbio.0060004 · Cited by 325

Central Autonomic System

Saper, C. B., & Stornetta, R. L. (2004) · Elsevier eBooks · doi:10.1016/b978-0-12-374245-2.00023-1 · Cited by 325

The Circadian Clock Component BMAL1 Is a Critical Regulator of p21 Expression and Hepatocyte Proliferation

Gréchez‐Cassiau, A., Rayet, B., Guillaumond, F., Teboul, M., & Delaunay, F. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m705576200 · Cited by 324

Circadian clock control of the cellular response to DNA damage

Sancar, A., Lindsey‐Boltz, L. A., Kang, T., Reardon, J. T., Lee, J. H., & Öztürk, N. (2010) · FEBS Letters · doi:10.1016/j.febslet.2010.03.017 · Cited by 322

Diurnal cortisol rhythm as a predictor of lung cancer survival

Sephton, S. E., Cash, E. D., Dedert, E. A., Floyd, A. R., Rebholz, W. N., Dhabhar, F. S., Spiegel, D., & Salmon, P. M. (2012) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2012.07.019 · Cited by 322

Neurons and networks in daily rhythms

Herzog, E. D. (2007) · Nature reviews. Neuroscience · doi:10.1038/nrn2215 · Cited by 321

It's time to swim! Zebrafish and the circadian clock

Vatine, G. D., Vallone, D., Gothilf, Y., & Foulkes, N. S. (2011) · FEBS Letters · doi:10.1016/j.febslet.2011.04.007 · Cited by 318

Rhythmic Messenger Ribonucleic Acid Expression of Clock Genes and Adipocytokines in Mouse Visceral Adipose Tissue

Ando, H., Yanagihara, H., Hayashi, Y., Obi, Y., Tsuruoka, S., Takamura, T., Kaneko, S., & Fujimura, A. (2005) · Endocrinology · doi:10.1210/en.2005-0771 · Cited by 315

Adora2b-elicited Per2 stabilization promotes a HIF-dependent metabolic switch crucial for myocardial adaptation to ischemia

Eckle, T., Hartmann, K., Bonney, S., Reithel, S., Mittelbronn, M., Walker, L. A., Lowes, B. D., Han, J., Borchers, C. H., Buttrick, P. M., et al. (2012) · Nature Medicine · doi:10.1038/nm.2728 · Cited by 314

Cryptochromes

Cashmore, A. R. (2003) · Cell · doi:10.1016/s0092-8674(03)00647-0 · Cited by 315

Coupling of Human Circadian and Cell Cycles by the Timeless Protein

Ünsal-Kaçmaz, K., Mullen, T. E., Kaufmann, W. K., & Sancar, A. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.8.3109-3116.2005 · Cited by 310

Acute Physical Stress Elevates Mouse Period1 mRNA Expression in Mouse Peripheral Tissues via a Glucocorticoid-responsive Element

Yamamoto, T., Nakahata, Y., Tanaka, M., Yoshida, M., Soma, H., Shinohara, K., Yasuda, A., Mamine, T., & Takumi, T. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m509600200 · Cited by 309

Transcriptional oscillation of canonical clock genes in mouse peripheral tissues

Yamamoto, T., Nakahata, Y., Soma, H., Akashi, M., Mamine, T., & Takumi, T. (2004) · BMC Molecular Biology · doi:10.1186/1471-2199-5-18 · Cited by 308

A noncanonical E-box enhancer drives mouse Period2 circadian oscillations in vivo

Yoo, S. H., Ko, C. H., Lowrey, P. L., Buhr, E. D., Song, E.-J., Chang, S., Yoo, O. J., Yamazaki, S., Lee, C., & Takahashi, J. S. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0409763102 · Cited by 307

Neurobiological mechanisms for the regulation of mammalian sleep–wake behavior: Reinterpretation of historical evidence and inclusion of contemporary cellular and molecular evidence

Datta, S., & MacLean, R. R. (2007) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2007.02.004 · Cited by 307

The histone methyltransferase MLL1 permits the oscillation of circadian gene expression

Katada, S., & Sassone‐Corsi, P. (2010) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1961 · Cited by 302

Melatonin and pregnancy in the human

Tamura, H., Nakamura, Y., Terrón, M. P., Flores, L. J., Manchester, L. C., Tan, D.-X., Sugino, N., & Reiter, R. J. (2008) · Reproductive Toxicology · doi:10.1016/j.reprotox.2008.03.005 · Cited by 297

SCFβ-TRCP Controls Clock-dependent Transcription via Casein Kinase 1-dependent Degradation of the Mammalian Period-1 (Per1) Proteinm

Shirogane, T., Jin, J., Cambronne, X. A., & Harper, J. W. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m502862200 · Cited by 296

The relationship between nutrition and circadian rhythms in mammals

Froy, O. (2007) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2007.03.001 · Cited by 295

Light and Cognition: Roles for Circadian Rhythms, Sleep, and Arousal

Fisk, A. S., Tam, S. K. E., Brown, L. A., Vyazovskiy, V. V., Bannerman, D. M., & Peirson, S. N. (2018) · Frontiers in Neurology · doi:10.3389/fneur.2018.00056 · Cited by 295

Melatonin receptors, heterodimerization, signal transduction and binding sites: what's new?

Jockers, R., Maurice, P., Boutin, J. A., & Delagrange, P. (2008) · British Journal of Pharmacology · doi:10.1038/bjp.2008.184 · Cited by 293

Scheduled exercise phase shifts the circadian clock in skeletal muscle

WOLFF, G., & ESSER, K. A. (2012) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e318255cf4c · Cited by 291

Microglia inflammatory responses are controlled by an intrinsic circadian clock

Fonken, L. K., Frank, M. G., Kitt, M. M., Barrientos, R. M., Watkins, L. R., & Maier, S. F. (2014) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2014.11.009 · Cited by 291

Emerging Roles of the Membrane Potential: Action Beyond the Action Potential

Kadir, L. A., Stacey, M. W., & Barrett‐Jolley, R. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.01661 · Cited by 290

Neurophysiology of sleep and wakefulness: basic science and clinical implications

Schwartz, J., & Roth, T. (2008) · Current Neuropharmacology · doi:10.2174/157015908787386050 · Cited by 289

Molecular Circadian Rhythms in Central and Peripheral Clocks in Mammals

Dardente, H., Dardente, H., & Cermakian, N. (2007) · Chronobiology International · doi:10.1080/07420520701283693 · Cited by 289

Circadian neuron feedback controls the Drosophila sleep–activity profile

Guo, F., Yu, J., Jung, H. J., Abruzzi, K. C., Luo, W., Griffith, L. C., & Rosbash, M. (2016) · Nature · doi:10.1038/nature19097 · Cited by 289

Mode of action of agomelatine: Synergy between melatonergic and 5-HT2Creceptors

Racagni, G., Riva, M. A., Molteni, R., Musazzi, L., Calabrese, F., Popoli, M., & Tardito, D. (2011) · The World Journal of Biological Psychiatry · doi:10.3109/15622975.2011.595823 · Cited by 287

Disrupting Circadian Homeostasis of Sympathetic Signaling Promotes Tumor Development in Mice

Lee, S., Donehower, L. A., Herron, A. J., Moore, D. D., & Fu, L. (2010) · PLoS ONE · doi:10.1371/journal.pone.0010995 · Cited by 286

A chemical biology approach reveals period shortening of the mammalian circadian clock by specific inhibition of GSK-3β

Hirota, T., Lewis, W. G., Liu, A. C., Lee, J. W., Schultz, P. G., & Kay, S. A. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0811410106 · Cited by 285

Clocks, cancer, and chronochemotherapy

Sancar, A., & Gelder, R. N. V. (2020) · Science · doi:10.1126/science.abb0738 · Cited by 285

The loss of circadian PAR bZip transcription factors results in epilepsyPreprint

Gachon, F., Fonjallaz, P., Damiola, F., Gos, P., Kodama, T., Zákány, J., Duboule, D., Petit, B., Tafti, M., & Schibler, U. (2004) · Genes & Development · doi:10.1101/gad.301404 · Cited by 285

Seasonal variation and the immune response: A fish perspective

Bowden, T. J., Thompson, K. D., Morgan, A. L., Gratacap, R. M. L., & Nikoskelainen, S. (2006) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2006.08.016 · Cited by 284

Circadian molecular clocks and cancer

Kelleher, F. C., Rao, A. D., & Maguire, A. (2013) · Cancer Letters · doi:10.1016/j.canlet.2013.09.040 · Cited by 283

The Orphan Nuclear Receptor Rev-erbα Recruits the N-CoR/Histone Deacetylase 3 Corepressor to Regulate the Circadian Bmal1 Gene

Yin, L., & Lazar, M. A. (2005) · Molecular Endocrinology · doi:10.1210/me.2005-0057 · Cited by 283

Mechanisms of DNA Repair by Photolyase and Excision Nuclease (Nobel Lecture)

Sancar, A. (2016) · Angewandte Chemie International Edition · doi:10.1002/anie.201601524 · Cited by 283

Circadian Clocks and Metabolism

Marcheva, B., Ramsey, K. M., Peek, C. B., Affinati, A., Maury, E., & Bass, J. (2013) · Handbook of Experimental Pharmacology · doi:10.1007/978-3-642-25950-0_6 · Cited by 282

Melatonin effects on the hypothalamo–pituitary axis in fish

Falcón, J., Besseau, L., Sauzet, S., & Bœuf, G. (2007) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2007.01.002 · Cited by 280

Temporal Precision in the Mammalian Circadian System: A Reliable Clock from Less Reliable Neurons

Herzog, E. D., Aton, S. J., Numano, R., Sakaki, Y., & Tei, H. (2004) · Journal of Biological Rhythms · doi:10.1177/0748730403260776 · Cited by 280

Properties, Entrainment, and Physiological Functions of Mammalian Peripheral Oscillators

Stratmann, M., & Schibler, U. (2006) · Journal of Biological Rhythms · doi:10.1177/0748730406293889 · Cited by 277

Circadian sensitivity to the chemotherapeutic agent cyclophosphamide depends on the functional status of the CLOCK/BMAL1 transactivation complex

Gorbacheva, V., Kondratov, R. V., Zhang, R., Cherukuri, S., Gudkov, A. V., Takahashi, J. S., & Antoch, M. P. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0409897102 · Cited by 275

Cycles in epilepsy

Karoly, P. J., Rao, V. R., Gregg, N. M., Worrell, G. A., Bernard, C., Cook, M. J., & Baud, M. O. (2021) · Nature Reviews Neurology · doi:10.1038/s41582-021-00464-1 · Cited by 275

Circadian rhythm and the gut microbiome

Voigt, R. M., Forsyth, C. B., Green, S. J., Engen, P. A., & Keshavarzian, A. (2016) · International Review of Neurobiology · doi:10.1016/bs.irn.2016.07.002 · Cited by 274

Melatonin feedback on clock genes: a theory involving the proteasome

Vriend, J. P., & Reiter, R. J. (2014) · Journal of Pineal Research · doi:10.1111/jpi.12189 · Cited by 274

Network Features of the Mammalian Circadian Clock

Baggs, J. E., Price, T. S., DiTacchio, L., Panda, S., FitzGerald, G. A., & Hogenesch, J. B. (2009) · PLoS Biology · doi:10.1371/journal.pbio.1000052 · Cited by 274

Glucocorticoid signaling synchronizes the liver circadian transcriptome

Reddy, A. B., Maywood, E. S., Karp, N. A., King, V. M., Inoue, Y., Gonzalez, F. J., Lilley, K. S., Kyriacou, C. P., & Hastings, M. H. (2007) · Hepatology · doi:10.1002/hep.21571 · Cited by 272

Separate oscillating cell groups in mouse suprachiasmatic nucleus couple photoperiodically to the onset and end of daily activity

Inagaki, N., Honma, S., Ono, D., Tanahashi, Y., & Honma, K. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0607713104 · Cited by 271

Neural circuits underlying thirst and fluid homeostasis

Zimmerman, C. A., Leib, D. E., & Knight, Z. A. (2017) · Nature reviews. Neuroscience · doi:10.1038/nrn.2017.71 · Cited by 268

The genetics of circadian rhythms, sleep and health

Jagannath, A., Taylor, L., Wakaf, Z., Vasudevan, S. R., & Foster, F. (2017) · Human Molecular Genetics · doi:10.1093/hmg/ddx240 · Cited by 269

HPA Axis‐Rhythms

Spiga, F., Walker, J. J., Terry, J. R., & Lightman, S. L. (2014) · Comprehensive Physiology · doi:10.1002/cphy.c140003 · Cited by 267

Human Gut Bacteria Are Sensitive to Melatonin and Express Endogenous Circadian Rhythmicity

Paulose, J. K., Wright, J. M., Patel, A., & Cassone, V. M. (2016) · PLoS ONE · doi:10.1371/journal.pone.0146643 · Cited by 266

Circadian rhythms in rheumatoid arthritis: Implications for pathophysiology and therapeutic management

Straub, R. H., & Cutolo, M. (2007) · Arthritis & Rheumatism · doi:10.1002/art.22368 · Cited by 265

Cold-Inducible RNA-Binding Protein Modulates Circadian Gene Expression Posttranscriptionally

Morf, J., Rey, G., Schneider, K., Stratmann, M., Fujita, J., Naef, F., & Schibler, U. (2012) · Science · doi:10.1126/science.1217726 · Cited by 265

Delay in Feedback Repression by Cryptochrome 1 Is Required for Circadian Clock Function

Ukai‐Tadenuma, M., Yamada, R. G., Xu, H., Ripperger, J. A., Liu, A. C., & Ueda, H. R. (2011) · Cell · doi:10.1016/j.cell.2010.12.019 · Cited by 264

Resetting Mechanism of Central and Peripheral Circadian Clocks in Mammals

Hirota, T., & Fukada, Y. (2004) · ZOOLOGICAL SCIENCE · doi:10.2108/zsj.21.359 · Cited by 264

The role of mPer2 clock gene in glucocorticoid and feeding rhythms

Yang, S., Liu, A., Weidenhammer, A., Cooksey, R. C., McClain, D., Kim, M. K., Aguilera, G., Abel, E. D., & Chung, J. H. (2009) · Endocrinology · doi:10.1210/en.2008-0705 · Cited by 263

Measurement of internal body time by blood metabolomics

Minami, Y., Kasukawa, T., Kakazu, Y., Iigo, M., Sugimoto, M., Ikeda, S., Yasui, A., van der Horst, G. T. J., Soga, T., & Ueda, H. R. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0900617106 · Cited by 263

Elevated Serum Cytokines Correlated with Altered Behavior, Serum Cortisol Rhythm, and Dampened 24-Hour Rest-Activity Patterns in Patients with Metastatic Colorectal Cancer

Rich, T. A., Innominato, P. F., Boerner, J. L., Mormont, M., Iacobelli, S., Baron, B., Jasmin, C., & Lévi, F. (2005) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-04-2000 · Cited by 262

Cellular Clocks in AVP Neurons of the SCN Are Critical for Interneuronal Coupling Regulating Circadian Behavior Rhythm

Mieda, M., Ono, D., Hasegawa, E., Okamoto, H., Honma, K., Honma, S., & Sakurai, T. (2015) · Neuron · doi:10.1016/j.neuron.2015.02.005 · Cited by 260

Defining chronodisruption

Erren, T. C., & Reiter, R. J. (2009) · Journal of Pineal Research · doi:10.1111/j.1600-079x.2009.00665.x · Cited by 260

Circadian clocks: setting time by food

Mendoza, J. (2007) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2006.01510.x · Cited by 257

The mammalian circadian clock

Albrecht, U., & Gregor Eichele, C. (2003) · Current Opinion in Genetics & Development · doi:10.1016/s0959-437x(03)00055-8 · Cited by 239

Systems Chronobiology: Global Analysis of Gene Regulation in a 24-Hour Periodic WorldPreprint

Mermet, J., Yeung, J., & Naef, F. (2016) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a028720 · Cited by 43

The Circadian Timing System: A Coordinator of Life Processes [Chronobiological Investigations]

Lévi, F. (2008) · IEEE Engineering in Medicine and Biology Magazine · doi:10.1109/memb.2007.907361 · Cited by 7

Understanding Quantitative Circadian Regulations Are Crucial Towards Advancing Chronotherapy

Chowdhury, D., Wang, C., Lü, A., & Zhu, H. (2019) · Cells · doi:10.3390/cells8080883 · Cited by 24

The Suprachiasmatic Nucleus and the Circadian Timekeeping System of the Body

Silver, R., & Rainbow, M. N. (2012) · Springer eBooks · doi:10.1007/978-1-4614-1997-6_66 · Cited by 16