Cited by 351Circadian rhythm and melatoninSleep and Work-Related FatigueSleep and Wakefulness Research

Sleep and circadian rhythms: key components in the regulation of energy metabolism

Laposky, Aaron D., Bass, Joseph, Kohsaka, Akira, Turek, Fred W.·2008·FEBS Letters

Abstract

In this review, we present evidence from human and animal studies to evaluate the hypothesis that sleep and circadian rhythms have direct impacts on energy metabolism, and represent important mechanisms underlying the major health epidemics of obesity and diabetes. The first part of this review will focus on studies that support the idea that sleep loss and obesity are "interacting epidemics." The second part will discuss recent evidence that the circadian clock system plays a fundamental role in energy metabolism at both the behavioral and molecular levels. These lines of research must be seen as in their infancy, but nevertheless, have provided a conceptual and experimental framework that potentially has great importance for understanding metabolic health and disease.

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Crossref · 10.1016/j.febslet.2007.06.079

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Authors
Laposky, A. D., Bass, J., Kohsaka, A., & Turek, F. W.
Affiliations
Northwestern University (US)
Corresponding author
Laposky, Aaron D.
Venue
FEBS Letters
Publisher
Wiley
Published
2007-08-14
Volume
582
Issue
1
Pages
142-151
ISSN
  • 0014-5793 (ISSN-L)
  • 1873-3468
OpenAlex
W1970654981
Cited by
351
References
74
Citations by year
2026: 8 · 2025: 11 · 2024: 15 · 2023: 15 · 2022: 13 · 2021: 20 · 2020: 15 · 2019: 21 · 2018: 13 · 2017: 20 · 2016: 26 · 2015: 15 · 2014: 24 · 2013: 24 · 2012: 19
FWCI
2.43
Type
journal article
Language
en
Open access
closed
Locations
  • FEBS Letters (publishedVersion)
  • PubMed (publishedVersion)
Funders
National Institute on Aging (P01AG011412)
Topics
  • Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and Work-Related Fatigue
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
Keywords
sleep, circadian rhythm, circadian clock, energy metabolism, obesity, diabetes mellitus, sleep deprivation, metabolic health, metabolic disorders
MeSH terms
Animals, Circadian Rhythm, Energy Metabolism, Humans, Obesity, Sleep, Sleep Deprivation

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