International AIDS Society global scientific strategy: towards an HIV cure 2016

Chimeric Antigen Receptor T Cells for Sustained Remissions in Leukemia

Maude, S. L., Frey, N., Shaw, P. A., Aplenc, R., Barrett, D. M., Bunin, N. J., Chew, A., Gonzalez, V. E., Zheng, Z., Lacey, S. F., et al. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1407222 · Cited by 5,413

Chimeric Antigen Receptor–Modified T Cells for Acute Lymphoid Leukemia

Grupp, S. A., Kalos, M., Barrett, D., Aplenc, R., Porter, D. L., Rheingold, S. R., Teachey, D. T., Chew, A., Hauck, B., Wright, J. F., et al. (2013) · New England Journal of Medicine · doi:10.1056/nejmoa1215134 · Cited by 3,509

Long-Term Control of HIV by CCR5 Delta32/Delta32 Stem-Cell Transplantation

Hütter, G., Nowak, D., Mossner, M., Ganepola, S., Müßig, A., Allers, K., Schneider, T., Hofmann, J., Kücherer, C., Blau, O., et al. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0802905 · Cited by 1,837

HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation

Chomont, N., El-Far, M., Ancuta, P., Trautmann, L., Procopio, F. A., Yassine-Diab, B., Boucher, G., Boulassel, M.-R., Ghattas, G., Brenchley, J. M., et al. (2009) · Nature Medicine · doi:10.1038/nm.1972 · Cited by 1,722

Replication-competent noninduced proviruses in the latent reservoir increase barrier to HIV-1 cure

Ho, Y.-C., Shan, L., Hosmane, N. N., Wang, J., Laskey, S. B., Rosenbloom, D. I. S., Lai, J., Blankson, J. N., Siliciano, J. D., & Siliciano, R. F. (2013) · Cell · doi:10.1016/j.cell.2013.09.020 · Cited by 1,405

Gene Editing of CCR5 in Autologous CD4 T Cells of Persons Infected with HIV

Tebas, P., Stein, D., Tang, W. W., Frank, I., Wang, S. Q., Lee, G., Spratt, S. K., Surosky, R. T., Giedlin, M. A., Nichol, G., et al. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1300662 · Cited by 1,357

The Major Genetic Determinants of HIV-1 Control Affect HLA Class I Peptide Presentation

Study, T. I. H. C. (2010) · Science · doi:10.1126/science.1195271 · Cited by 1,171

Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy

Archin, N. M., Liberty, A. L., Kashuba, A. D., Choudhary, S. K., Kuruc, J. D., Crooks, A. M., Parker, D. C., Anderson, E. M., Kearney, M. F., Strain, M. C., et al. (2012) · Nature · doi:10.1038/nature11286 · Cited by 1,139

Post-Treatment HIV-1 Controllers with a Long-Term Virological Remission after the Interruption of Early Initiated Antiretroviral Therapy ANRS VISCONTI Study

Sáez-Cirión, A., Bacchus, C., Hocqueloux, L., Avettand-Fenoel, V., Girault, I., Lecuroux, C., Potard, V., Versmisse, P., Melard, A., Prazuck, T., et al. (2013) · PLoS Pathogens · doi:10.1371/journal.ppat.1003211 · Cited by 1,011

Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine

Hansen, S. G., Ford, J. C., Lewis, M. S., Ventura, A. B., Hughes, C. M., Coyne-Johnson, L., Whizin, N., Oswald, K., Shoemaker, R., Swanson, T., et al. (2011) · Nature · doi:10.1038/nature10003 · Cited by 988

Specific HIV integration sites are linked to clonal expansion and persistence of infected cells

Maldarelli, F., Wu, X., Su, L., Simonetti, F. R., Shao, W., Hill, S., Spindler, J., Ferris, A. L., Mellors, J. W., Kearney, M. F., et al. (2014) · Science · doi:10.1126/science.1254194 · Cited by 849

Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117

Caskey, M., Klein, F., Lorenzi, J. C. C., Seaman, M. S., West, A. P., Buckley, N., Kremer, G., Nogueira, L., Braunschweig, M., Scheid, J. F., et al. (2015) · Nature · doi:10.1038/nature14411 · Cited by 767

Stimulation of HIV-1-Specific Cytolytic T Lymphocytes Facilitates Elimination of Latent Viral Reservoir after Virus Reactivation

Shan, L., Deng, K., Shroff, N. S., Durand, C. M., Rabi, S. A., Yang, H.-C., Zhang, H., Margolick, J. B., Blankson, J. N., & Siliciano, R. F. (2012) · Immunity · doi:10.1016/j.immuni.2012.01.014 · Cited by 714

Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection

Wagner, T. A., McLaughlin, S., Garg, K., Cheung, C. Y. K., Larsen, B. B., Styrchak, S., Huang, H. C., Edlefsen, P. T., Mullins, J. I., & Frenkel, L. M. (2014) · Science · doi:10.1126/science.1256304 · Cited by 677

Persistent HIV-1 replication is associated with lower antiretroviral drug concentrations in lymphatic tissues

Fletcher, C. V., Staskus, K., Wietgrefe, S. W., Rothenberger, M., Reilly, C., Chipman, J. G., Beilman, G. J., Khoruts, A., Thorkelson, A., Schmidt, T. E., et al. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1318249111 · Cited by 664

Therapeutic efficacy of potent neutralizing HIV-1-specific monoclonal antibodies in SHIV-infected rhesus monkeys

Barouch, D. H., Whitney, J. B., Moldt, B., Klein, F., Oliveira, T. Y., Liu, J., Stephenson, K. E., Chang, H.-W., Shekhar, K., Gupta, S., et al. (2013) · Nature · doi:10.1038/nature12744 · Cited by 644

Rapid seeding of the viral reservoir prior to SIV viraemia in rhesus monkeys

Whitney, J. B., Hill, A. L., Sanisetty, S., Penaloza-MacMaster, P., Liu, J., Shetty, M., Parenteau, L., Cabral, C., Shields, J., Blackmore, S., et al. (2014) · Nature · doi:10.1038/nature13594 · Cited by 629

Panobinostat, a histone deacetylase inhibitor, for latent-virus reactivation in HIV-infected patients on suppressive antiretroviral therapy: a phase 1/2, single group, clinical trial

Rasmussen, T. A., Tolstrup, M., Brinkmann, C. R., Olesen, R., Erikstrup, C., Solomon, A., Winckelmann, A., Palmer, S., Dinarello, C., Buzon, M., et al. (2014) · The Lancet HIV · doi:10.1016/s2352-3018(14)70014-1 · Cited by 628

Persistent HIV-1 replication maintains the tissue reservoir during therapy

Lorenzo-Redondo, R., Fryer, H. R., Bedford, T., Kim, E.-Y., Archer, J., Kosakovsky Pond, S. L., Chung, Y.-S., Penugonda, S., Chipman, J. G., Fletcher, C. V., et al. (2016) · Nature · doi:10.1038/nature16933 · Cited by 627

Immune clearance of highly pathogenic SIV infection

Hansen, S. G., Jr, M. P., Ventura, A. B., Hughes, C. M., Gilbride, R. M., Ford, J. C., Oswald, K., Shoemaker, R., Li, Y., Lewis, M. S., et al. (2013) · Nature · doi:10.1038/nature12519 · Cited by 597

Absence of Detectable HIV-1 Viremia after Treatment Cessation in an Infant

Persaud, D., Gay, H., Ziemniak, C., Chen, Y. H., Piatak, M., Chun, T.-W., Strain, M., Richman, D., & Luzuriaga, K. (2013) · New England Journal of Medicine · doi:10.1056/nejmoa1302976 · Cited by 581

Transcriptional activation and chromatin remodeling of the HIV-1 promoter in response to histone acetylation.

Van Lint, C., Emiliani, S., Ott, M., & Verdin, E. (1996) · The EMBO Journal · doi:10.1002/j.1460-2075.1996.tb00449.x · Cited by 580

Comparative Analysis of Measures of Viral Reservoirs in HIV-1 Eradication Studies

Eriksson, S., Graf, E. H., Dahl, V., Strain, M. C., Yukl, S. A., Lysenko, E. S., Bosch, R. J., Lai, J., Chioma, S., Emad, F., et al. (2013) · PLoS Pathogens · doi:10.1371/journal.ppat.1003174 · Cited by 567

Towards an HIV cure: a global scientific strategy

The International AIDS Society Scientific Working Group on HIV Cure (2012) · Nature Reviews Immunology · doi:10.1038/nri3262 · Cited by 554

HIV-1 replication and immune dynamics are affected by raltegravir intensification of HAART-suppressed subjects

J Buzón, M., Massanella, M., Llibre, J. M., Esteve, A., Dahl, V., Puertas, M. C., Gatell, J. M., Domingo, P., Paredes, R., Sharkey, M., et al. (2010) · Nature Medicine · doi:10.1038/nm.2111 · Cited by 551

RNA-directed gene editing specifically eradicates latent and prevents new HIV-1 infection

Hu, W., Kaminski, R., Yang, F., Zhang, Y., Cosentino, L., Li, F., Luo, B., Alvarez-Carbonell, D., Garcia-Mesa, Y., Karn, J., et al. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1405186111 · Cited by 527

The Depsipeptide Romidepsin Reverses HIV-1 Latency In Vivo

Søgaard, O. S., Graversen, M. E., Leth, S., Olesen, R., Brinkmann, C. R., Nissen, S. K., Kjaer, A. S., Schleimann, M. H., Denton, P. W., Hey-Cunningham, W. J., et al. (2015) · PLOS Pathogens · doi:10.1371/journal.ppat.1005142 · Cited by 516

Depletion of latent HIV-1 infection in vivo: a proof-of-concept study

Lehrman, G., Hogue, I. B., Palmer, S., Jennings, C., Spina, C. A., Wiegand, A., Landay, A. L., Coombs, R. W., Richman, D. D., Mellors, J. W., et al. (2005) · The Lancet · doi:10.1016/s0140-6736(05)67098-5 · Cited by 510

Activation of HIV Transcription with Short-Course Vorinostat in HIV-Infected Patients on Suppressive Antiretroviral Therapy

Elliott, J. H., Wightman, F., Solomon, A., Ghneim, K., Ahlers, J., Cameron, M. J., Smith, M. Z., Spelman, T., McMahon, J., Velayudham, P., et al. (2014) · PLoS Pathogens · doi:10.1371/journal.ppat.1004473 · Cited by 504

Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations

Deng, K., Pertea, M., Rongvaux, A., Wang, L., Durand, C. M., Ghiaur, G., Lai, J., McHugh, H. L., Hao, H., Zhang, H., et al. (2015) · Nature · doi:10.1038/nature14053 · Cited by 504

B cell follicle sanctuary permits persistent productive simian immunodeficiency virus infection in elite controllers

Fukazawa, Y., Lum, R., Okoye, A. A., Park, H., Matsuda, K., Bae, J. Y., Hagen, S. I., Shoemaker, R., Deleage, C., Lucero, C., et al. (2015) · Nature Medicine · doi:10.1038/nm.3781 · Cited by 477

PD-1+ and follicular helper T cells are responsible for persistent HIV-1 transcription in treated aviremic individuals

Banga, R., Procopio, F. A., Noto, A., Pollakis, G., Cavassini, M., Ohmiti, K., Corpataux, J.-M., de Leval, L., Pantaleo, G., & Perreau, M. (2016) · Nature Medicine · doi:10.1038/nm.4113 · Cited by 471

Virologic effects of broadly neutralizing antibody VRC01 administration during chronic HIV-1 infection

Lynch, R. M., Boritz, E., Coates, E. E., DeZure, A., Madden, P., Costner, P., Enama, M. E., Plummer, S., Holman, L., Hendel, C. S., et al. (2015) · Science Translational Medicine · doi:10.1126/scitranslmed.aad5752 · Cited by 465

Cytomegalovirus Vectors Violate CD8 + T Cell Epitope Recognition Paradigms

Hansen, S. G., Sacha, J. B., Hughes, C. M., Ford, J. C., Burwitz, B. J., Scholz, I., Gilbride, R. M., Lewis, M. S., Gilliam, A. N., Ventura, A. B., et al. (2013) · Science · doi:10.1126/science.1237874 · Cited by 432

HIV-1 persistence in CD4+ T cells with stem cell–like properties

Buzon, M. J., Sun, H., Li, C., Shaw, A., Seiss, K., Ouyang, Z., Martin-Gayo, E., Leng, J., Henrich, T. J., Li, J. Z., et al. (2014) · Nature Medicine · doi:10.1038/nm.3445 · Cited by 414

Precise Quantitation of the Latent HIV-1 Reservoir: Implications for Eradication Strategies

Crooks, A. M., Bateson, R., Cope, A. B., Dahl, N. P., Griggs, M. K., Kuruc, J. D., Gay, C. L., Eron, J. J., Margolis, D. M., Bosch, R. J., et al. (2015) · Journal of Infectious Diseases · doi:10.1093/infdis/jiv218 · Cited by 406

An In-Depth Comparison of Latent HIV-1 Reactivation in Multiple Cell Model Systems and Resting CD4+ T Cells from Aviremic Patients

Spina, C. A., Anderson, J., Archin, N. M., Bosque, A., Chan, J., Famiglietti, M., Greene, W. C., Kashuba, A., Lewin, S. R., Margolis, D. M., et al. (2013) · PLoS Pathogens · doi:10.1371/journal.ppat.1003834 · Cited by 403

Antiretroviral-Free HIV-1 Remission and Viral Rebound After Allogeneic Stem Cell Transplantation: Report of 2 Cases

Henrich, T. J., Hanhauser, E., Marty, F. M., Sirignano, M. N., Keating, S., Lee, T.-H., Robles, Y. P., Davis, B. T., Li, J. Z., Heisey, A., et al. (2014) · Annals of Internal Medicine · doi:10.7326/m14-1027 · Cited by 401

Ex vivo analysis identifies effective HIV-1 latency–reversing drug combinations

Laird, G. M., Bullen, C. K., Rosenbloom, D. I. S., Martin, A. R., Hill, A. L., Durand, C. M., Siliciano, J. D., & Siliciano, R. F. (2015) · Journal of Clinical Investigation · doi:10.1172/jci80142 · Cited by 391

Broadly Neutralizing Antibodies and Viral Inducers Decrease Rebound from HIV-1 Latent Reservoirs in Humanized Mice

Halper-Stromberg, A., Lu, C.-L., Klein, F., Horwitz, J. A., Bournazos, S., Nogueira, L., Eisenreich, T. R., Liu, C., Gazumyan, A., Schaefer, U., et al. (2014) · Cell · doi:10.1016/j.cell.2014.07.043 · Cited by 381

RNA-Based Gene Therapy for HIV with Lentiviral Vector–Modified CD34 + Cells in Patients Undergoing Transplantation for AIDS-Related Lymphoma

DiGiusto, D. L., Krishnan, A., Li, L., Li, H., Li, S., Rao, A., Mi, S., Yam, P., Stinson, S., Kalos, M., et al. (2010) · Science Translational Medicine · doi:10.1126/scitranslmed.3000931 · Cited by 374

Clonally expanded CD4 + T cells can produce infectious HIV-1 in vivo

Simonetti, F. R., Sobolewski, M. D., Fyne, E., Shao, W., Spindler, J., Hattori, J., Anderson, E. M., Watters, S. A., Hill, S., Wu, X., et al. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1522675113 · Cited by 372

The Human Factors YY1 and LSF Repress the Human Immunodeficiency Virus Type 1 Long Terminal Repeat via Recruitment of Histone Deacetylase 1

Coull, J. J., Romerio, F., Sun, J.-M., Volker, J. L., Galvin, K. M., Davie, J. R., Shi, Y., Hansen, U., & Margolis, D. M. (2000) · Journal of Virology · doi:10.1128/jvi.74.15.6790-6799.2000 · Cited by 346

Past, present and future: 30 years of HIV research

Barré-Sinoussi, F., Ross, A. L., & Delfraissy, J.-F. (2013) · Nature Reviews Microbiology · doi:10.1038/nrmicro3132 · Cited by 332

AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges

Gardner, M. R., Kattenhorn, L. M., Kondur, H. R., von Schaewen, M., Dorfman, T., Chiang, J. J., Haworth, K. G., Decker, J. M., Alpert, M. D., Bailey, C. C., et al. (2015) · Nature · doi:10.1038/nature14264 · Cited by 298

HIV-1 DNA predicts disease progression and post-treatment virological control

Williams, J. P., Hurst, J., Stöhr, W., Robinson, N., Brown, H., Fisher, M., Kinloch, S., Cooper, D., Schechter, M., Tambussi, G., et al. (2014) · eLife · doi:10.7554/elife.03821 · Cited by 293

Challenges in Detecting HIV Persistence during Potentially Curative Interventions: A Study of the Berlin Patient

Yukl, S. A., Boritz, E., Busch, M., Bentsen, C., Chun, T.-W., Douek, D., Eisele, E., Haase, A., Ho, Y.-C., Hütter, G., et al. (2013) · PLoS Pathogens · doi:10.1371/journal.ppat.1003347 · Cited by 291

Broadly targeted CD8 + T cell responses restricted by major histocompatibility complex E

Hansen, S. G., Wu, H. L., Burwitz, B. J., Hughes, C. M., Hammond, K. B., Ventura, A. B., Reed, J. S., Gilbride, R. M., Ainslie, E., Morrow, D. W., et al. (2016) · Science · doi:10.1126/science.aac9475 · Cited by 290

The size of the expressed HIV reservoir predicts timing of viral rebound after treatment interruption

Li, J. Z., Etemad, B., Ahmed, H., Aga, E., Bosch, R. J., Mellors, J. W., Kuritzkes, D. R., Lederman, M. M., Para, M., & Gandhi, R. T. (2015) · AIDS · doi:10.1097/qad.0000000000000953 · Cited by 287

The HIV-1 reservoir in eight patients on long-term suppressive antiretroviral therapy is stable with few genetic changes over time

Josefsson, L., von Stockenstrom, S., Faria, N. R., Sinclair, E., Bacchetti, P., Killian, M., Epling, L., Tan, A., Ho, T., Lemey, P., et al. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1308313110 · Cited by 277

A Novel Assay to Measure the Magnitude of the Inducible Viral Reservoir in HIV-infected Individuals

Procopio, F. A., Fromentin, R., Kulpa, D. A., Brehm, J. H., Bebin, A.-G., Strain, M. C., Richman, D. D., O'Doherty, U., Palmer, S., Hecht, F. M., et al. (2015) · EBioMedicine · doi:10.1016/j.ebiom.2015.06.019 · Cited by 261

Macrophages sustain HIV replication in vivo independently of T cells

Honeycutt, J. B., Wahl, A., Baker, C., Spagnuolo, R. A., Foster, J., Zakharova, O., Wietgrefe, S., Caro-Vegas, C., Madden, V., Sharpe, G., et al. (2016) · Journal of Clinical Investigation · doi:10.1172/jci84456 · Cited by 253

Cell-Based Measures of Viral Persistence Are Associated With Immune Activation and Programmed Cell Death Protein 1 (PD-1)–Expressing CD4+ T cells

Hatano, H., Jain, V., Hunt, P. W., Lee, T.-H., Sinclair, E., Do, T. D., Hoh, R., Martin, J. N., McCune, J. M., Hecht, F., et al. (2013) · The Journal of Infectious Diseases · doi:10.1093/infdis/jis630 · Cited by 251

Short-term administration of disulfiram for reversal of latent HIV infection: a phase 2 dose-escalation study

Elliott, J. H., McMahon, J. H., Chang, C. C., Lee, S. A., Hartogensis, W., Bumpus, N., Savic, R., Roney, J., Hoh, R., Solomon, A., et al. (2015) · The Lancet HIV · doi:10.1016/s2352-3018(15)00226-x · Cited by 250

Interleukin-7 promotes HIV persistence during antiretroviral therapy

Vandergeeten, C., Fromentin, R., DaFonseca, S., Lawani, M. B., Sereti, I., Lederman, M. M., Ramgopal, M., Routy, J.-P., Sékaly, R.-P., & Chomont, N. (2013) · Blood · doi:10.1182/blood-2012-11-465625 · Cited by 249

Establishment of HIV Latency in Primary CD4+Cells Is due to Epigenetic Transcriptional Silencing and P-TEFb Restriction

Tyagi, M., Pearson, R. J., & Karn, J. (2010) · Journal of Virology · doi:10.1128/jvi.01519-09 · Cited by 249

Rapid Quantification of the Latent Reservoir for HIV-1 Using a Viral Outgrowth Assay

Laird, G. M., Eisele, E. E., Rabi, S. A., Lai, J., Chioma, S., Blankson, J. N., Siliciano, J. D., & Siliciano, R. F. (2013) · PLoS Pathogens · doi:10.1371/journal.ppat.1003398 · Cited by 239

Vectored immunoprophylaxis protects humanized mice from mucosal HIV transmission

Balazs, A. B., Ouyang, Y., Hong, C. M., Chen, J., Nguyen, S. M., Rao, D. S., An, D. S., & Baltimore, D. (2014) · Nature Medicine · doi:10.1038/nm.3471 · Cited by 237

BET bromodomain-targeting compounds reactivate HIV from latency via a Tat-independent mechanism

Boehm, D., Calvanese, V., Dar, R. D., Xing, S., Schroeder, S., Martins, L., Aull, K., Li, P.-C., Planelles, V., Bradner, J. E., et al. (2013) · Cell Cycle · doi:10.4161/cc.23309 · Cited by 235

Lack of Detectable HIV-1 Molecular Evolution during Suppressive Antiretroviral Therapy

Kearney, M. F., Spindler, J., Shao, W., Yu, S., Anderson, E. M., O'Shea, A., Rehm, C., Poethke, C., Kovacs, N., Mellors, J. W., et al. (2014) · PLoS Pathogens · doi:10.1371/journal.ppat.1004010 · Cited by 235

Quantification of HIV-1 latency reversal in resting CD4 + T cells from patients on suppressive antiretroviral therapy

Cillo, A. R., Sobolewski, M. D., Bosch, R. J., Fyne, E., Piatak, M., Coffin, J. M., & Mellors, J. W. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1402873111 · Cited by 232

The Tat Inhibitor Didehydro-Cortistatin A Prevents HIV-1 Reactivation from Latency

Mousseau, G., Kessing, C. F., Fromentin, R., Trautmann, L., Chomont, N., & Valente, S. T. (2015) · mBio · doi:10.1128/mbio.00465-15 · Cited by 231

CTL Fail to Accumulate at Sites of HIV-1 Replication in Lymphoid Tissue

Connick, E., Mattila, T., Folkvord, J. M., Schlichtemeier, R., Meditz, A. L., Ray, M. G., McCarter, M. D., MaWhinney, S., Hage, A., White, C., et al. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.178.11.6975 · Cited by 223

Immediate antiviral therapy appears to restrict resting CD4 + cell HIV-1 infection without accelerating the decay of latent infection

Archin, N. M., Vaidya, N. K., Kuruc, J. D., Liberty, A. L., Wiegand, A., Kearney, M. F., Cohen, M. S., Coffin, J. M., Bosch, R. J., Gay, C. L., et al. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1120248109 · Cited by 221

Orientation-Dependent Regulation of Integrated HIV-1 Expression by Host Gene Transcriptional Readthrough

Han, Y., Lin, Y. B., An, W., Xu, J., Yang, H.-C., O'Connell, K., Dordai, D., Boeke, J. D., Siliciano, J. D., & Siliciano, R. F. (2008) · Cell Host & Microbe · doi:10.1016/j.chom.2008.06.008 · Cited by 215

Immunologic strategies for HIV-1 remission and eradication

Barouch, D. H., & Deeks, S. G. (2014) · Science · doi:10.1126/science.1255512 · Cited by 211

Histone Deacetylase Inhibitors Impair the Elimination of HIV-Infected Cells by Cytotoxic T-Lymphocytes

Jones, R. B., O'Connor, R., Mueller, S., Foley, M., Szeto, G. L., Karel, D., Lichterfeld, M., Kovacs, C., Ostrowski, M. A., Trocha, A., et al. (2014) · PLoS Pathogens · doi:10.1371/journal.ppat.1004287 · Cited by 206

Generation of HIV Latency in Humanized BLT Mice

Denton, P. W., Olesen, R., Choudhary, S. K., Archin, N. M., Wahl, A., Swanson, M. D., Chateau, M., Nochi, T., Krisko, J. F., Spagnuolo, R. A., et al. (2012) · Journal of Virology · doi:10.1128/jvi.06120-11 · Cited by 202

The Distribution of HIV DNA and RNA in Cell Subsets Differs in Gut and Blood of HIV-Positive Patients on ART: Implications for Viral Persistence

Yukl, S. A., Shergill, A. K., Ho, T., Killian, M., Girling, V., Epling, L., Li, P., Wong, L. K., Crouch, P., Deeks, S. G., et al. (2013) · The Journal of Infectious Diseases · doi:10.1093/infdis/jit308 · Cited by 184

Increase in 2–Long Terminal Repeat Circles and Decrease in D-dimer After Raltegravir Intensification in Patients With Treated HIV Infection: A Randomized, Placebo-Controlled Trial

Hatano, H., Strain, M. C., Scherzer, R., Bacchetti, P., Wentworth, D., Hoh, R., Martin, J. N., McCune, J. M., Neaton, J. D., Tracy, R. P., et al. (2013) · The Journal of Infectious Diseases · doi:10.1093/infdis/jit453 · Cited by 173

Immunological biomarkers predict HIV-1 viral rebound after treatment interruption

Hurst, J., Hoffmann, M., Pace, M., Williams, J. P., Thornhill, J., Hamlyn, E., Meyerowitz, J., Willberg, C., Koelsch, K. K., Robinson, N., et al. (2015) · Nature Communications · doi:10.1038/ncomms9495 · Cited by 170

Whole-body immunoPET reveals active SIV dynamics in viremic and antiretroviral therapy–treated macaques

Santangelo, P. J., Rogers, K. A., Zurla, C., Blanchard, E. L., Gumber, S., Strait, K., Connor-Stroud, F., Schuster, D. M., Amancha, P. K., Hong, J. J., et al. (2015) · Nature Methods · doi:10.1038/nmeth.3320 · Cited by 167

HIV-1 virological remission lasting more than 12 years after interruption of early antiretroviral therapy in a perinatally infected teenager enrolled in the French ANRS EPF-CO10 paediatric cohort: a case report

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Effect of ipilimumab on the HIV reservoir in an HIV-infected individual with metastatic melanoma

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