Pro-cognitive properties of T cells

From inflammation to sickness and depression: when the immune system subjugates the brain

Dantzer, R., O'Connor, J. C., Freund, G. G., Johnson, R. W., & Kelley, K. W. (2008) · Nature Reviews Neuroscience · doi:10.1038/nrn2297 · Cited by 7,395 · see citing works

Tolerance, Danger, and the Extended Family

Matzinger, P. (1994) · Annual Review of Immunology · doi:10.1146/annurev.iy.12.040194.005015 · Cited by 4,848 · see citing works

Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin

Borovikova, L. V., Ivanova, S., Zhang, M., Yang, H., Botchkina, G. I., Watkins, L. R., Wang, H., Abumrad, N., Eaton, J. W., & Tracey, K. J. (2000) · Nature · doi:10.1038/35013070 · Cited by 4,211 · see citing works

The Sympathetic Nerve—An Integrative Interface between Two Supersystems: The Brain and the Immune System

Elenkov, I. J., Wilder, R. L., Chrousos, G. P., & Vizi, E. S. (2000) · Pharmacological Reviews · doi:10.1016/s0031-6997(24)01470-4 · Cited by 2,252 · see citing works

Acetylcholine-Synthesizing T Cells Relay Neural Signals in a Vagus Nerve Circuit

Rosas-Ballina, M., Olofsson, P. S., Ochani, M., Valdés-Ferrer, S. I., Levine, Y. A., Reardon, C., Tusche, M. W., Pavlov, V. A., Andersson, U., Chavan, S., et al. (2011) · Science · doi:10.1126/science.1209985 · Cited by 1,551 · see citing works

Immune cells contribute to the maintenance of neurogenesis and spatial learning abilities in adulthood

Ziv, Y., Ron, N., Butovsky, O., Landa, G., Sudai, E., Greenberg, N., Cohen, H., Kipnis, J., & Schwartz, M. (2006) · Nature Neuroscience · doi:10.1038/nn1629 · Cited by 1,209 · see citing works

Reflex control of immunity

Tracey, K. J. (2009) · Nature Reviews Immunology · doi:10.1038/nri2566 · Cited by 1,154 · see citing works

Autoimmune T cells protect neurons from secondary degeneration after central nervous system axotomy

Moalem‐Taylor, G., Leibowitz‐Amit, R., Yoles, E., Mor, F., Cohen, I. R., & Schwartz, M. (1999) · Nature Medicine · doi:10.1038/4734 · Cited by 882 · see citing works

Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation

Korn, T., Reddy, J., Gao, W., Bettelli, E., Awasthi, A., Petersen, T. R., Bäckström, B. T., Sobel, R. A., Wucherpfennig, K. W., Strom, T. B., et al. (2007) · Nature Medicine · doi:10.1038/nm1564 · Cited by 812 · see citing works

Regulation of learning and memory by meningeal immunity: a key role for IL-4

Derecki, N. C., Cardani, A. N., Yang, C. H., Quinnies, K. M., Crihfield, A., Lynch, K. R., & Kipnis, J. (2010) · Journal of Experimental Medicine · doi:10.1084/jem.20091419 · Cited by 800 · see citing works

MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-α–PU.1 pathway

Ponomarev, E. D., Veremeyko, T., Barteneva, N., Krichevsky, A. M., & Weiner, H. L. (2011) · Nature Medicine · doi:10.1038/nm.2266 · Cited by 787 · see citing works

Infiltrating Blood-Derived Macrophages Are Vital Cells Playing an Anti-inflammatory Role in Recovery from Spinal Cord Injury in Mice

Shechter, R., London, A., Varol, C., Raposo, C., Cusimano, M., Yovel, G., Rolls, A., Mack, M., Pluchino, S., Martino, G., et al. (2009) · PLoS Medicine · doi:10.1371/journal.pmed.1000113 · Cited by 770 · see citing works

Brain interleukin-1 mediates chronic stress-induced depression in mice via adrenocortical activation and hippocampal neurogenesis suppression

Goshen, I., Kreisel, T., Ben-Menachem-Zidon, O., Licht, T., Weidenfeld, J., Ben-Hur, T., & Yirmiya, R. (2008) · Molecular Psychiatry · doi:10.1038/sj.mp.4002055 · Cited by 762 · see citing works

Cytokine-induced sickness behavior

Kelley, K. W., Bluthé, R.-M., Dantzer, R., Zhou, J.-H., Shen, W.-H., Johnson, R. W., & Broussard, S. R. (2003) · Brain, Behavior, and Immunity · doi:10.1016/s0889-1591(02)00077-6 · Cited by 716 · see citing works

The ins and outs of T-lymphocyte trafficking to the CNS: anatomical sites and molecular mechanisms

Engelhardt, B., & Ransohoff, R. M. (2005) · Trends in Immunology · doi:10.1016/j.it.2005.07.004 · Cited by 676 · see citing works

Differential regulation of central nervous system autoimmunity by TH1 and TH17 cells

Stromnes, I. M., Cerretti, L., Liggitt, D., Harris, R. A., & Goverman, J. M. (2008) · Nature Medicine · doi:10.1038/nm1715 · Cited by 626 · see citing works

Human cerebrospinal fluid central memory CD4 + T cells: Evidence for trafficking through choroid plexus and meninges via P-selectin

Kivisäkk, P., Mahad, D., Callahan, M. K., Trebst, C., Tucky, B. H., Wei, T., Wu, L., Bækkevold, E. S., Lassmann, H., Staugaitis, S. M., et al. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1433000100 · Cited by 546 · see citing works

What is the blood–brain barrier (not)?

Bechmann, I., Galea, I., & Perry, V. H. (2007) · Trends in Immunology · doi:10.1016/j.it.2006.11.007 · Cited by 520 · see citing works

T cell deficiency leads to cognitive dysfunction: Implications for therapeutic vaccination for schizophrenia and other psychiatric conditions

Kipnis, J., Cohen, H., Cardon, M., Ziv, Y., & Schwartz, M. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0402268101 · Cited by 510 · see citing works

Activated leukocyte cell adhesion molecule promotes leukocyte trafficking into the central nervous system

Cayrol, R., Wosik, K., Berard, J. L., Dodelet-Devillers, A., Ifergan, I., Kebir, H., Haqqani, A. S., Kreymborg, K., Krug, S., Moumdjian, R., et al. (2008) · Nature Immunology · doi:10.1038/ni1551 · Cited by 444 · see citing works

Interleukin-1β in Immune Cells of the Abdominal Vagus Nerve: a Link between the Immune and Nervous Systems?

Goehler, L. E., Gaykema, R. P. A., Nguyen, K. T., Lee, J. E., Tilders, F. J. H., Maier, S. F., & Watkins, L. R. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-07-02799.1999 · Cited by 357 · see citing works

Multiple roles of chemokine CXCL12 in the central nervous system: A migration from immunology to neurobiology

Li, M., & Ransohoff, R. M. (2007) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2007.11.003 · Cited by 352 · see citing works

Protective Autoimmunity Is a Physiological Response to CNS Trauma

Yoles, E., Hauben, E., Palgi, O., Agranov, E., Gothilf, A., Cohen, A., Kuchroo, V. K., Cohen, I. R., Weiner, H. L., & Schwartz, M. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-11-03740.2001 · Cited by 344 · see citing works

Tissue-based class control: the other side of tolerance

Matzinger, P., & Kamala, T. (2011) · Nature reviews. Immunology · doi:10.1038/nri2940 · Cited by 343 · see citing works

Production of Neurotrophins by Activated T Cells: Implications for Neuroprotective Autoimmunity

Moalem‐Taylor, G., Gdalyahu, A., Shani, Y., Otten, U., Lazarovici, P., Cohen, I. R., & Schwartz, M. (2000) · Journal of Autoimmunity · doi:10.1006/jaut.2000.0441 · Cited by 337 · see citing works

A critical review of chronic stress effects on spatial learning and memory

Conrad, C. D. (2009) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2009.11.003 · Cited by 335 · see citing works

CD4-positive T lymphocytes provide a neuroimmunological link in the control of adult hippocampal neurogenesis

Wolf, S. A., Steiner, B., Akpinarli, A., Kammertoens, T., Nassenstein, C., Braun, A., Blankenstein, T., & Kempermann, G. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0801218 · Cited by 329 · see citing works

Role of High-Affinity Receptors and Membrane Transporters in Nonsynaptic Communication and Drug Action in the Central Nervous System

Vizi, E. S. (2000) · Pharmacological Reviews · doi:10.1016/s0031-6997(24)01436-4 · Cited by 311 · see citing works

Localizing CNS immune surveillance: Meningeal APCs activate T cells during EAE

Kivisäkk, P., Imitola, J., Rasmussen, S., Elyaman, W., Zhu, B., Ransohoff, R., & Khoury, S. J. (2009) · Annals of Neurology · doi:10.1002/ana.21379 · Cited by 281 · see citing works

Expression of CCR7 in multiple sclerosis: implications for CNS immunity

Kivisäkk, P., Mahad, D. J., Callahan, M. K., Sikora, K., Trebst, C., Tucky, B., Wujek, J., Ravid, R., Staugaitis, S. M., Lassmann, H., et al. (2004) · Annals of Neurology · doi:10.1002/ana.20049 · Cited by 267 · see citing works

Adiponectin inhibits Toll‐like receptor family‐induced signaling

Yamaguchi, N., Argueta, J. G. M., Masuhiro, Y., Kagishita, M., Nonaka, K., Saito, T., Hanazawa, S., & Yamashita, Y. (2005) · FEBS Letters · doi:10.1016/j.febslet.2005.11.019 · Cited by 259 · see citing works

Autoimmune concepts of multiple sclerosis as a basis for selective immunotherapy: From pipe dreams to (therapeutic) pipelines

Hohlfeld, R., & Wekerle, H. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0404874101 · Cited by 239 · see citing works

Neuronal Survival after CNS Insult Is Determined by a Genetically Encoded Autoimmune Response

Kipnis, J., Yoles, E., Schori, H., Hauben, E., Shaked, I., & Schwartz, M. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-13-04564.2001 · Cited by 230 · see citing works

Degeneration of spared axons following partial white matter lesion: implications for optic nerve neuropathies.

Yoles, E., & Schwartz, M. (1998) · Experimental Neurology · doi:10.1006/exnr.1998.6811 · Cited by 228 · see citing works

Dopamine by itself activates either D2, D3 or D1/D5 dopaminergic receptors in normal human T-cells and triggers the selective secretion of either IL-10, TNFα or both

Besser, M. J., Ganor, Y., & Levite, M. (2005) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2005.07.013 · Cited by 222 · see citing works

Adaptive immunity affects learning behavior in mice

Brynskikh, A., Warren, T., Zhu, J., & Kipnis, J. (2008) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2007.12.008 · Cited by 221 · see citing works

Protective autoimmunity: interferon‐γ enables microglia to remove glutamate without evoking inflammatory mediators

Shaked, I., Tchoresh, D., Gersner, R., Meiri, G., Mordechai, S., Xiao, X., Hart, R. P., & Schwartz, M. (2005) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2004.02954.x · Cited by 210 · see citing works

Posttraumatic therapeutic vaccination with modified myelin self-antigen prevents complete paralysis while avoiding autoimmune disease

Hauben, E., Agranov, E., Gothilf, A., Nevo, U., Cohen, A., Smirnov, I., Steinman, L., & Schwartz, M. (2001) · Journal of Clinical Investigation · doi:10.1172/jci12837 · Cited by 208 · see citing works

Flt3L controls the development of radiosensitive dendritic cells in the meninges and choroid plexus of the steady-state mouse brain

Anandasabapathy, N., Victora, G. D., Meredith, M. M., Feder, R. E., Dong, B., Kluger, C., Yao, K.-H., Dustin, M. L., Nussenzweig, M. C., Steinman, R. M., et al. (2011) · The Journal of Experimental Medicine · doi:10.1084/jem.20102657 · Cited by 207 · see citing works

Angiotensin II sustains brain inflammation in mice via TGF-β

Lanz, T. V., Ding, Z., Ho, P. P.-K., Luo, J., Agrawal, A., Srinagesh, H. K., Axtell, R. C., Zhang, H., Platten, M., Wyss‐Coray, T., et al. (2010) · Journal of Clinical Investigation · doi:10.1172/jci41709 · Cited by 200 · see citing works

Dopamine, through the Extracellular Signal-Regulated Kinase Pathway, Downregulates CD4+CD25+Regulatory T-Cell Activity: Implications for Neurodegeneration

Kipnis, J., Cardon, M., Avidan, H., Lewitus, G. M., Mordechay, S., Rolls, A., Shani, Y., & Schwartz, M. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.0600-04.2004 · Cited by 187 · see citing works

Brain mast cells link the immune system to anxiety-like behavior

Nautiyal, K. M., Ribeiro, A. C. D. M., Pfaff, D. W., & Silver, R. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0809479105 · Cited by 186 · see citing works

Maladaptation to mental stress mitigated by the adaptive immune system via depletion of naturally occurring regulatory CD4+CD25+ cells

Cohen, H., Ziv, Y., Cardon, M., Kaplan, Z., Matar, M. A., Gidron, Y., Schwartz, M., & Kipnis, J. (2006) · Journal of Neurobiology · doi:10.1002/neu.20249 · Cited by 173 · see citing works

Dopamine β-hydroxylase deficiency impairs cellular immunity

Alaniz, R. C., THOMAS, S. A., Pérez‐Melgosa, M., Mueller, K., Farr, A. G., Palmiter, R. D., & Wilson, C. B. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.5.2274 · Cited by 155 · see citing works

Neuroprotection by IL-10-producing MOG CD4+ T cells following ischemic stroke.

Frenkel, D., Huang, Z., Maron, R., Koldzic, D. N., Moskowitz, M., & Weiner, H. (2005) · Journal of Neurological Sciences · doi:10.1016/j.jns.2005.03.022 · Cited by 141 · see citing works

BDNF upregulation during declarative memory formation in monkey inferior temporal cortex

Tokuyama, W., Okuno, H., Hashimoto, T., Li, Y. X., & Miyashita, Y. (2000) · Nature Neuroscience · doi:10.1038/80655 · Cited by 135 · see citing works

Activation of kinin receptor B1 limits encephalitogenic T lymphocyte recruitment to the central nervous system

Schulze-Topphoff, U., Prat, A., Prozorovski, T., Siffrin, V., Paterka, M., Herz, J., Bendix, I., Ifergan, I., Schadock, I., Mori, M. A., et al. (2009) · Nature Medicine · doi:10.1038/nm.1980 · Cited by 131 · see citing works

Reducing post-traumatic anxiety by immunization

Lewitus, G. M., Cohen, H., & Schwartz, M. (2008) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2008.05.002 · Cited by 123 · see citing works

Vaccination as a Novel Approach for Treating Depressive Behavior

Lewitus, G. M., Wilf-Yarkoni, A., Ziv, Y., Shabat-Simon, M., Gersner, R., Zangen, A., & Schwartz, M. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.07.014 · Cited by 109 · see citing works

Age-Dependent T Cell Tolerance and Autoimmunity to Myelin Basic Protein

Huseby, E. S., Sather, B. D., Huseby, P. G., & Goverman, J. M. (2001) · Immunity · doi:10.1016/s1074-7613(01)00127-3 · Cited by 109 · see citing works

Neuroprotective Immunity: T Cell-Derived Glutamate Endows Astrocytes with a Neuroprotective Phenotype

Garg, S. K., Banerjee, R. V., & Kipnis, J. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.180.6.3866 · Cited by 106 · see citing works

Upregulation of hippocampal TrkB and synaptotagmin is involved in treadmill exercise-enhanced aversive memory in mice

Liu, Y.-F., Chen, H.-I., Yu, L., Kuo, Y.-M., Wu, F.-S., Chuang, J.-I., Liao, P.-C., & Jen, C. J. (2008) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2008.02.005 · Cited by 98 · see citing works

Alternatively activated myeloid (M2) cells enhance cognitive function in immune compromised mice

Derecki, N. C., Quinnies, K. M., & Kipnis, J. (2010) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2010.11.009 · Cited by 97 · see citing works

Vaccination with Dendritic Cells Pulsed with Peptides of Myelin Basic Protein Promotes Functional Recovery from Spinal Cord Injury

Hauben, E., Gothilf, A., Cohen, A., Butovsky, O., Nevo, U., Smirnov, I., Yoles, E., AKSELROD, S., & Schwartz, M. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-25-08808.2003 · Cited by 96 · see citing works

Autoimmune T cells retard the loss of function in injured rat optic nerves

Moalem‐Taylor, G., Yoles, E., Leibowitz‐Amit, R., Muller-Gilor, S., Mor, F., Cohen, I. R., & Schwartz, M. (2000) · Journal of Neuroimmunology · doi:10.1016/s0165-5728(00)00240-x · Cited by 90 · see citing works

Impaired TrkB receptor signaling contributes to memory impairment in APP/PS1 mice

Kemppainen, S., Rantamäki, T., Jerónimo-Santos, A., Lavasseur, G., Autio, H., Karpova, N. N., Kärkkäinen, E., Stavén, S., Miranda, H. V., Outeiro, T. F., et al. (2011) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2011.11.006 · Cited by 89 · see citing works

T cell-derived lymphotoxin regulates liver regeneration

Tumanov, A. V., Koroleva, E. P., Christiansen, P. A., Khan, M. A., Ruddy, M. J., Burnette, B., Papa, S., Franzoso, G., Nedospasov, S. A., Fu, Y., et al. (2009) · Gastroenterology · doi:10.1053/j.gastro.2008.09.015 · Cited by 89 · see citing works

Adaptive peripheral immune response increases proliferation of neural precursor cells in the adult hippocampus

Wolf, S. A., Steiner, B., Wengner, A. M., Lipp, M., Kammertoens, T., & Kempermann, G. (2009) · The FASEB Journal · doi:10.1096/fj.08-113944 · Cited by 80 · see citing works

Dopamine suppresses IL-12 p40 production by lipopolysaccharide-stimulated macrophages via a β-adrenoceptor-mediated mechanism

Haskó, G., Szabó, C., Németh, Z. H., & Deitch, E. A. (2002) · Journal of Neuroimmunology · doi:10.1016/s0165-5728(01)00459-3 · Cited by 77 · see citing works

Postsynaptic BDNF signalling regulates long‐term potentiation at thalamo‐amygdala afferents

Meis, S., Endres, T., & Leßmann, V. (2011) · The Journal of Physiology · doi:10.1113/jphysiol.2011.220434 · Cited by 76 · see citing works

Brain-derived neurotrophic factor supports facial motoneuron survival after facial nerve transection in immunodeficient mice

Serpe, C. J., Byram, S. C., Sanders, V. M., & Jones, K. J. (2004) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2004.07.005 · Cited by 46 · see citing works

Human cerebrospinal fluid contains CD4+ memory T cells expressing gut- or skin-specific trafficking determinants: relevance for immunotherapy

Kivisäkk, P., Tucky, B. H., Wei, T., Campbell, J. J., & Ransohoff, R. M. (2006) · BMC Immunology · doi:10.1186/1471-2172-7-14 · Cited by 45 · see citing works

Blood-borne donor mast cell precursors migrate to mast cell-rich brain regions in the adult mouse

Nautiyal, K. M., Liu, C., Dong, X. Z., & Silver, R. (2011) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2011.09.003 · Cited by 25 · see citing works

Chemokines and chemokine receptors in the nervous system

Trettel, F., Angelantonio, S. D., Limatola, C., & Ransohoff, R. M. (2008) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2008.04.006 · Cited by 5 · see citing works

Untitled work

(1998) · doi:10.1002/(sici)1098-1063(1998)8:6

Structural and functional features of central nervous system lymphatic vessels

Louveau, A., Smirnov, I., Keyes, T. J., Eccles, J. D., Rouhani, S. J., Peske, J. D., Derecki, N. C., Castle, D., Mandell, J. W., Lee, K. S., et al. (2015) · Nature · doi:10.1038/nature14432 · Cited by 4,413 · see citing works

Neuroinflammation: The Devil Is in the Details

DiSabato, D. J., Quan, N., & Godbout, J. P. (2016) · Journal of Neurochemistry · doi:10.1111/jnc.13607 · Cited by 1,640 · see citing works

Depression as a Microglial Disease

Yirmiya, R., Rimmerman, N., & Reshef, R. (2015) · Trends in Neurosciences · doi:10.1016/j.tins.2015.08.001 · Cited by 944 · see citing works

The gut-brain axis: how microbiota and host inflammasome influence brain physiology and pathology

Rutsch, A., Kantsjö, J. B., & Ronchi, F. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.604179 · Cited by 821 · see citing works

Integrating neuroimmune systems in the neurobiology of depression

Wohleb, E. S., Franklin, T., Iwata, M., & Duman, R. S. (2016) · Nature Reviews Neuroscience · doi:10.1038/nrn.2016.69 · Cited by 668 · see citing works

Revisiting the Mechanisms of CNS Immune Privilege

Louveau, A., Harris, T. H., & Kipnis, J. (2015) · Trends in Immunology · doi:10.1016/j.it.2015.08.006 · Cited by 682 · see citing works

Aging-induced type I interferon response at the choroid plexus negatively affects brain function

Baruch, K., Deczkowska, A., David, E., Castellano, J. M., Miller, O., Kertser, A., Berkutzki, T., Barnett-Itzhaki, Z., Bezalel, D., Wyss-Coray, T., et al. (2014) · Science · doi:10.1126/science.1252945 · Cited by 615 · see citing works

Inflammation in neurodegenerative diseases—An update

Amor, S., Peferoen, L. A. N., Vogel, D. Y. S., Breur, M., van der Valk, P., Baker, D., & van Noort, J. M. (2014) · Immunology · doi:10.1111/imm.12233 · Cited by 550 · see citing works

Immune mediators in the brain and peripheral tissues in autism spectrum disorder

Estes, M. L., & McAllister, A. K. (2015) · Nature Reviews Neuroscience · doi:10.1038/nrn3978 · Cited by 514 · see citing works

Psychoneuroimmunology of early-life stress: the hidden wounds of childhood trauma?

Danese, A., & J Lewis, S. (2017) · Neuropsychopharmacology · doi:10.1038/npp.2016.198 · Cited by 393 · see citing works

Multifaceted interactions between adaptive immunity and the central nervous system

Kipnis, J. (2016) · Science · doi:10.1126/science.aag2638 · Cited by 376 · see citing works

Microglia Require CD4 T Cells to Complete the Fetal-to-Adult Transition

Pasciuto, E., Burton, O. T., Roca, C. P., Lagou, V., Rajan, W. D., Theys, T., Mancuso, R., Tito, R. Y., Kouser, L., Callaerts-Vegh, Z., et al. (2020) · Cell · doi:10.1016/j.cell.2020.06.026 · Cited by 368 · see citing works

Dealing with danger in the CNS: the response of the immune system to injury

Gadani, S. P., Walsh, J. T., Lukens, J. R., & Kipnis, J. (2015) · Neuron · doi:10.1016/j.neuron.2015.05.019 · Cited by 342 · see citing works

The resolution of neuroinflammation in neurodegeneration: leukocyte recruitment via the choroid plexus

Schwartz, M., & Baruch, K. (2014) · The EMBO Journal · doi:10.1002/embj.201386609 · Cited by 349 · see citing works

Meningeal γδ T cell-derived IL-17 controls synaptic plasticity and short-term memory

Ribeiro, M., Brigas, H. C., Temido-Ferreira, M., Pousinha, P. A., Regen, T., Santa, C., Coelho, J. E., Marques-Morgado, I., Valente, C. A., Omenetti, S., et al. (2019) · Science Immunology · doi:10.1126/sciimmunol.aay5199 · Cited by 335 · see citing works

Hidden wounds? inflammatory links between childhood trauma and psychopathology

Danese, A., & Baldwin, J. R. (2017) · Annual Review of Psychology · doi:10.1146/annurev-psych-010416-044208 · Cited by 286 · see citing works

Immune cells and CNS physiology: Microglia and beyond

Norris, G. T., & Kipnis, J. (2019) · Journal of Experimental Medicine · doi:10.1084/jem.20180199 · Cited by 274 · see citing works

Deep cervical lymph node ligation aggravates AD‐like pathology of APP/PS1 mice

Wang, L., Zhang, Y., Zhao, Y., Marshall, C., Wu, T., & Xiao, M. (2019) · Brain Pathology · doi:10.1111/bpa.12656 · Cited by 199 · see citing works

Learning and memory … and the immune system

Marin, I., & Kipnis, J. (2013) · Learning & Memory · doi:10.1101/lm.028357.112 · Cited by 166 · see citing works

Maternal stress, nutrition and physical activity: Impact on immune function, CNS development and psychopathology

Marques, A. H., Bjørke-Monsen, A.-L., Teixeira, A. L., & Silverman, M. N. (2015) · Brain Research · doi:10.1016/j.brainres.2014.10.051 · Cited by 166 · see citing works

Immunity in amyotrophic lateral sclerosis: blurred lines between excessive inflammation and inefficient immune responses

Béland, L.-C., Markovinovic, A., Jakovac, H., De Marchi, F., Bilic, E., Mazzini, L., Kriz, J., & Munitic, I. (2020) · Brain Communications · doi:10.1093/braincomms/fcaa124 · Cited by 125 · see citing works

Dynamics of the meningeal CD4+ T-cell repertoire are defined by the cervical lymph nodes and facilitate cognitive task performance in mice

Radjavi, A., Smirnov, I., Derecki, N., & Kipnis, J. (2014) · Molecular Psychiatry · doi:10.1038/mp.2013.79 · Cited by 112 · see citing works

MHC class I immune proteins are critical for hippocampus-dependent memory and gate NMDAR-dependent hippocampal long-term depression

Nelson, P. A., Sage, J. R., Wood, S. C., Davenport, C. M., Anagnostaras, S. G., & Boulanger, L. M. (2013) · Learning & Memory · doi:10.1101/lm.031351.113 · Cited by 49 · see citing works

Neuroimmunology

Antel, J. P., & Owens, T. (2001) · Encyclopedia of Life Sciences · doi:10.1038/npg.els.0003072

Brain borders at the central stage of neuroimmunology

Rustenhoven, J., & Kipnis, J. (2022) · Nature · doi:10.1038/s41586-022-05474-7 · Cited by 253 · see citing works

Development weaves brains, bodies and environments into cognition

Sheya, A., & Smith, L. B. (2018) · Language Cognition and Neuroscience · doi:10.1080/23273798.2018.1489065 · Cited by 9 · see citing works

Nervous System-Immune System Interactions: An Overview

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