Why does the microbiome affect behaviour?

The genetical evolution of social behaviour. I

Hamilton, W. D. (1964) · Journal of Theoretical Biology · doi:10.1016/0022-5193(64)90038-4 · Cited by 15,725 · see citing works

A human gut microbial gene catalogue established by metagenomic sequencing

MetaHIT Consortium, Qin, J., Li, R., Raes, J., Arumugam, M., Burgdorf, K. S., Manichanh, C., Nielsen, T., Pons, N., Levenez, F., et al. (2010) · Nature · doi:10.1038/nature08821 · Cited by 11,624 · see citing works

From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites

Koh, A., De Vadder, F., Kovatcheva-Datchary, P., & Bäckhed, F. (2016) · Cell · doi:10.1016/j.cell.2016.05.041 · Cited by 7,070 · see citing works

Sociobiology: The New Synthesis.

Lenski, G. E., & Wilson, E. O. (1976) · Social Forces · doi:10.2307/2576242 · Cited by 6,271 · see citing works

Astrocyte-endothelial interactions at the blood-brain barrier

Abbott, N. J., Rönnbäck, L., & Hansson, E. (2006) · Nature Reviews Neuroscience · doi:10.1038/nrn1824 · Cited by 5,595 · see citing works

Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells

Furusawa, Y., Obata, Y., Fukuda, S., Endo, T. A., Nakato, G., Takahashi, D., Nakanishi, Y., Uetake, C., Kato, K., Kato, T., et al. (2013) · Nature · doi:10.1038/nature12721 · Cited by 5,549 · see citing works

The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic T _reg Cell Homeostasis

Smith, P. M., Howitt, M. R., Panikov, N., Michaud, M., Gallini, C. A., Bohlooly-Y, M., Glickman, J. N., & Garrett, W. S. (2013) · Science · doi:10.1126/science.1241165 · Cited by 5,413 · see citing works

Host-Bacterial Mutualism in the Human Intestine

Bäckhed, F., Ley, R. E., Sonnenburg, J. L., Peterson, D. A., & Gordon, J. I. (2005) · Science · doi:10.1126/science.1104816 · Cited by 5,277 · see citing works

Hay fever, hygiene, and household size.

Strachan, D. P. (1989) · BMJ · doi:10.1136/bmj.299.6710.1259 · Cited by 5,054 · see citing works

The gut microbiota shapes intestinal immune responses during health and disease

Round, J. L., & Mazmanian, S. K. (2009) · Nature Reviews Immunology · doi:10.1038/nri2515 · Cited by 5,029 · see citing works

Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour

Cryan, J. F., & Dinan, T. G. (2012) · Nature Reviews Neuroscience · doi:10.1038/nrn3346 · Cited by 4,572 · see citing works

Structural and functional features of central nervous system lymphatic vessels

Louveau, A., Smirnov, I., Keyes, T. J., Eccles, J. D., Rouhani, S. J., Peske, J. D., Derecki, N. C., Castle, D., Mandell, J. W., Lee, K. S., et al. (2015) · Nature · doi:10.1038/nature14432 · Cited by 4,413 · see citing works

The genetical evolution of social behaviour. II

Hamilton, W. D. O. (1964) · Journal of Theoretical Biology · doi:10.1016/0022-5193(64)90039-6 · Cited by 4,158 · see citing works

Ingestion of <i>Lactobacillus</i> strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve

Bravo, J. A., Forsythe, P., Chew, M. V., Escaravage, E., Savignac, H. M., Dinan, T. G., Bienenstock, J., & Cryan, J. F. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1102999108 · Cited by 3,888 · see citing works

Indigenous bacteria from the gut microbiota regulate host serotonin biosynthesis

Yano, J. M., Yu, K., Donaldson, G. P., Shastri, G. G., Ann, P., Ma, L., Nagler, C. R., Ismagilov, R. F., Mazmanian, S. K., & Hsiao, E. Y. (2015) · Cell · doi:10.1016/j.cell.2015.02.047 · Cited by 3,614 · see citing works

Gut microbiota, metabolites and host immunity

Rooks, M. G., & Garrett, W. S. (2016) · Nature reviews. Immunology · doi:10.1038/nri.2016.42 · Cited by 3,409 · see citing works

Microbiota Modulate Behavioral and Physiological Abnormalities Associated with Neurodevelopmental Disorders

Hsiao, E. Y., McBride, S. W., Hsien, S., Sharon, G., Hyde, E. R., McCue, T., Codelli, J. A., Chow, J., Reisman, S. E., Petrosino, J. F., et al. (2013) · Cell · doi:10.1016/j.cell.2013.11.024 · Cited by 3,283 · see citing works

Normal gut microbiota modulates brain development and behavior

Heijtz, R. D., Wang, S., Anuar, F., Qian, Y., Björkholm, B., Samuelsson, A., Hibberd, M. L., Forssberg, H., & Pettersson, S. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1010529108 · Cited by 3,228 · see citing works

The ecology of the microbiome: Networks, competition, and stability

Coyte, K. Z., Schlüter, J., & Foster, K. R. (2015) · Science · doi:10.1126/science.aad2602 · Cited by 2,728 · see citing works

The gut microbiota influences blood-brain barrier permeability in mice

Braniste, V., Al-Asmakh, M., Kowal, C., Anuar, F., Abbaspour, A., Tóth, M., Korecka, A., Bakocevic, N., Ng, L. G., Kundu, P., et al. (2014) · Science Translational Medicine · doi:10.1126/scitranslmed.3009759 · Cited by 2,530 · see citing works

Gut–brain axis: How the microbiome influences anxiety and depression

Foster, J. A., & McVey Neufeld, K.-A. (2013) · Trends in Neurosciences · doi:10.1016/j.tins.2013.01.005 · Cited by 2,460 · see citing works

Serotonin, tryptophan metabolism and the brain-gut-microbiome axis

O’Mahony, S. M., Clarke, G., Borre, Y. E., Dinan, T. G., & Cryan, J. F. (2015) · Behavioural Brain Research · doi:10.1016/j.bbr.2014.07.027 · Cited by 2,012 · see citing works

Interactions between the microbiota, immune and nervous systems in health and disease

Fung, T. C., Olson, C. A., & Hsiao, E. Y. (2017) · Nature Neuroscience · doi:10.1038/nn.4476 · Cited by 1,900 · see citing works

The short-chain fatty acid acetate reduces appetite via a central homeostatic mechanism

Frost, G., Sleeth, M. L., Sahuri-Arisoylu, M., Lizarbe, B., Cerdan, S., Brody, L., Anastasovska, J., Ghourab, S., Hankir, M., Zhang, S., et al. (2014) · Nature Communications · doi:10.1038/ncomms4611 · Cited by 1,771 · see citing works

The Intestinal Microbiota Affect Central Levels of Brain-Derived Neurotropic Factor and Behavior in Mice

Bercik, P., Denou, E., Collins, J., Jackson, W., Lu, J., Jury, J., Deng, Y., Blennerhassett, P., Macri, J., McCoy, K. D., et al. (2011) · Gastroenterology · doi:10.1053/j.gastro.2011.04.052 · Cited by 1,748 · see citing works

Gut feelings: the emerging biology of gut-brain communication

Mayer, E. A. (2011) · Nature Reviews Neuroscience · doi:10.1038/nrn3071 · Cited by 1,726 · see citing works

The central nervous system and the gut microbiome

Sharon, G., Sampson, T. R., Geschwind, D. H., & Mazmanian, S. K. (2016) · Cell · doi:10.1016/j.cell.2016.10.027 · Cited by 1,513 · see citing works

Basic Neurochemistry: Molecular, Cellular, and Medical Aspects

Siegel, G. J., & Agranoff, B. W. (1989) · Cited by 1,357 · see citing works

Principles and clinical implications of the brain-gut-enteric microbiota axis

Rhee, S. H., Pothoulakis, C., & Mayer, E. A. (2009) · Nature Reviews Gastroenterology &amp; Hepatology · doi:10.1038/nrgastro.2009.35 · Cited by 1,342 · see citing works

Gut microbes promote colonic serotonin production through an effect of short-chain fatty acids on enterochromaffin cells

Reigstad, C. S., Salmonson, C. E., III, J. F. R., Szurszewski, J. H., Linden, D. R., Sonnenburg, J. L., Farrugia, G., & Kashyap, P. C. (2015) · The FASEB Journal · doi:10.1096/fj.14-259598 · Cited by 1,335 · see citing works

Assessment of psychotropic-like properties of a probiotic formulation ( <i>Lactobacillus helveticus</i> R0052 and <i>Bifidobacterium longum</i> R0175) in rats and human subjects

Messaoudi, M., Lalonde, R., Violle, N., Javelot, H., Desor, D., Nejdi, A., Bisson, J.-F., Rougeot, C., Pichelin, M., Cazaubiel, M., et al. (2011) · British Journal of Nutrition · doi:10.1017/s0007114510004319 · Cited by 1,324 · see citing works

Microbial reconstitution reverses maternal diet-induced social and synaptic deficits in offspring

Buffington, S. A., Di Prisco, G. V., Auchtung, T. A., Ajami, N. J., Petrosino, J. F., & Costa-Mattioli, M. (2016) · Cell · doi:10.1016/j.cell.2016.06.001 · Cited by 1,163 · see citing works

γ-Aminobutyric acid production by culturable bacteria from the human intestine

Barrett, E., Ross, R. P., O'Toole, P. W., Fitzgerald, G. F., & Stanton, C. (2012) · Journal of Applied Microbiology · doi:10.1111/j.1365-2672.2012.05344.x · Cited by 1,156 · see citing works

Control of brain development, function, and behavior by the microbiome

Sampson, T. R., & Mazmanian, S. K. (2015) · Cell Host &amp; Microbe · doi:10.1016/j.chom.2015.04.011 · Cited by 1,093 · see citing works

Psychobiotics and the manipulation of bacteria–gut–brain signals

Sarkar, A., Lehto, S. M., Harty, S., Dinan, T. G., Cryan, J. F., & Burnet, P. W. J. (2016) · Trends in Neurosciences · doi:10.1016/j.tins.2016.09.002 · Cited by 1,068 · see citing works

The anxiolytic effect of Bifidobacterium longum NCC3001 involves vagal pathways for gut-brain communication

Bercik, P., Park, A. J., Sinclair, D., Khoshdel, A., Lu, J., Huang, X., Deng, Y., Blennerhassett, P. A., Fahnestock, M., Moine, D., et al. (2011) · Neurogastroenterology &amp; Motility · doi:10.1111/j.1365-2982.2011.01796.x · Cited by 1,018 · see citing works

Brain Serotonin Content: Physiological Dependence on Plasma Tryptophan Levels

Fernstrom, J. D., & Wurtman, R. J. (1971) · Science · doi:10.1126/science.173.3992.149 · Cited by 1,017 · see citing works

The vocabulary of microbiome research: a proposal

Marchesi, J., & Ravel, J. (2015) · Microbiome · doi:10.1186/s40168-015-0094-5 · Cited by 1,016 · see citing works

Effects of the probiotic Bifidobacterium infantis in the maternal separation model of depression

Desbonnet, L., Garrett, L., Clarke, G., Kiely, B., Cryan, J. F., & Dinan, T. G. (2010) · Neuroscience · doi:10.1016/j.neuroscience.2010.08.005 · Cited by 999 · see citing works

Commensal anaerobic gut bacteria attenuate inflammation by regulating nuclear-cytoplasmic shuttling of PPAR-γ and RelA

Kelly, D., Campbell, J. I., King, T. P., Grant, G., Jansson, E. Å., Coutts, A., Pettersson, S., & Conway, S. (2003) · Nature Immunology · doi:10.1038/ni1018 · Cited by 997 · see citing works

Spatial structure, cooperation and competition in biofilms

Nadell, C. D., Drescher, K., & Foster, K. R. (2016) · Nature Reviews Microbiology · doi:10.1038/nrmicro.2016.84 · Cited by 978 · see citing works

Host lifestyle affects human microbiota on daily timescales

David, L. A., Materna, A. C., Friedman, J., Campos-Baptista, M. I., Blackburn, M. C., Perrotta, A., Erdman, S. E., & Alm, E. J. (2014) · Genome biology · doi:10.1186/gb-2014-15-7-r89 · Cited by 950 · see citing works

Commensal bacteria at the interface of host metabolism and the immune system

Brestoff, J. R., & Artis, D. (2013) · Nature Immunology · doi:10.1038/ni.2640 · Cited by 945 · see citing works

The evolution of the host microbiome as an ecosystem on a leash

Foster, K. R., Schlüter, J., Coyte, K. Z., & Rakoff-Nahoum, S. (2017) · Nature · doi:10.1038/nature23292 · Cited by 923 · see citing works

Microbiota is essential for social development in the mouse

Desbonnet, L., Clarke, G., Shanahan, F., Dinan, T. G., & Cryan, J. F. (2014) · Molecular Psychiatry · doi:10.1038/mp.2013.65 · Cited by 866 · see citing works

Prokaryotic Regulation of Epithelial Responses by Inhibition of IκB-α Ubiquitination

Neish, A. S., Gewirtz, A. T., Zeng, H., Young, A. N., Hobert, M. E., Karmali, V., Rao, A. S., & Madara, J. (2000) · Science · doi:10.1126/science.289.5484.1560 · Cited by 843 · see citing works

Probiotic Bifidobacterium longum NCC3001 reduces depression scores and alters brain activity: a pilot study in patients with irritable bowel syndrome

Pinto-Sanchez, M. I., Hall, G. B., Ghajar, K., Nardelli, A., Bolino, C., Lau, J. T., Martin, F.-P., Cominetti, O., Welsh, C., Rieder, A., et al. (2017) · Gastroenterology · doi:10.1053/j.gastro.2017.05.003 · Cited by 821 · see citing works

Principles of Social Evolution

Bourke, A. F. G. (2011) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780199231157.001.0001 · Cited by 816 · see citing works

Gut microbiota depletion from early adolescence in mice: implications for brain and behaviour

Desbonnet, L., Clarke, G., Traplin, A., O’Sullivan, O., Crispie, F., Moloney, R. D., Cotter, P. D., Dinan, T. G., & Cryan, J. F. (2015) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2015.04.004 · Cited by 760 · see citing works

Fatal attraction in rats infected with Toxoplasma gondii

Berdoy, M., Webster, J. P., & Macdonald, D. W. (2000) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2000.1182 · Cited by 731 · see citing works

Sequencing and beyond: integrating molecular 'omics' for microbial community profiling

Franzosa, E. A., Hsu, T. Y., Sirota‐Madi, A., Shafquat, A., Abu-Ali, G., Morgan, X. C., & Huttenhower, C. (2015) · Nature Reviews Microbiology · doi:10.1038/nrmicro3451 · Cited by 725 · see citing works

Characteristics of Compounds that Cross the Blood-Brain Barrier

Banks, W. A. (2009) · BMC Neurology · doi:10.1186/1471-2377-9-s1-s3 · Cited by 710 · see citing works

Functional Redundancy-Induced Stability of Gut Microbiota Subjected to Disturbance

Moya, A., & Ferrer, M. (2016) · Trends in Microbiology · doi:10.1016/j.tim.2016.02.002 · Cited by 690 · see citing works

Integrating neuroimmune systems in the neurobiology of depression

Wohleb, E. S., Franklin, T., Iwata, M., & Duman, R. S. (2016) · Nature Reviews Neuroscience · doi:10.1038/nrn.2016.69 · Cited by 668 · see citing works

Critical role of gut microbiota in the production of biologically active, free catecholamines in the gut lumen of mice

Asano, Y., Hiramoto, T., Nishino, R., Aiba, Y., Kimura, T., Yoshihara, K., Koga, Y., & Sudo, N. (2012) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00341.2012 · Cited by 659 · see citing works

The bowel and beyond: The enteric nervous system in neurological disorders

Rao, M., & Gershon, M. D. (2016) · Nature Reviews Gastroenterology &amp; Hepatology · doi:10.1038/nrgastro.2016.107 · Cited by 629 · see citing works

Microbial endocrinology: the interplay between the microbiota and the endocrine system

Neuman, H., Debelius, J. W., Knight, R. D., & Koren, O. (2015) · FEMS Microbiology Reviews · doi:10.1093/femsre/fuu010 · Cited by 610 · see citing works

Ecological Modeling from Time-Series Inference: Insight into Dynamics and Stability of Intestinal Microbiota

Stein, R. R., Bucci, V., Toussaint, N. C., Buffie, C. G., Rätsch, G., Pamer, E. G., Sander, C., & Xavier, J. B. (2013) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1003388 · Cited by 604 · see citing works

Parasitic manipulation: where are we and where should we go?

Thomas, F., Adamo, S. A., & Moore, J. (2005) · Behavioural Processes · doi:10.1016/j.beproc.2004.06.010 · Cited by 587 · see citing works

Intestinal Bacteria and the Regulation of Immune Cell Homeostasis

Hill, D. A., & Artis, D. (2010) · Annual Review of Immunology · doi:10.1146/annurev-immunol-030409-101330 · Cited by 586 · see citing works

Vagal pathways for microbiome-brain-gut axis communication

Forsythe, P., Bienenstock, J., & Kunze, W. A. (2014) · Advances in Experimental Medicine and Biology · doi:10.1007/978-1-4939-0897-4_5 · Cited by 576 · see citing works

Behavioral changes induced by Toxoplasma infection of rodents are highly specific to aversion of cat odors

Vyas, A., Kim, S.-K., Giacomini, N., Boothroyd, J. C., & Sapolsky, R. M. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0608310104 · Cited by 571 · see citing works

Bifidobacterial surface-exopolysaccharide facilitates commensal-host interaction through immune modulation and pathogen protection

Fanning, S., Hall, L. J., Cronin, M. A., Zomer, A., MacSharry, J. A., Goulding, D., Motherway, M. O., Shanahan, F., Nally, K., Dougan, G., et al. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1115621109 · Cited by 564 · see citing works

Elaborate interactions between the immune and nervous systems

Steinman, L. (2004) · Nature Immunology · doi:10.1038/ni1078 · Cited by 556 · see citing works

“Adaptive” changes in the behaviour of parasitized animals: A critical review

Poulin, R. (1995) · International Journal for Parasitology · doi:10.1016/0020-7519(95)00100-x · Cited by 529 · see citing works

Transplantation of fecal microbiota from patients with irritable bowel syndrome alters gut function and behavior in recipient mice

De Palma, G., Lynch, M. D. J., Lu, J., Dang, V. T., Deng, Y., Jury, J., Umeh, G., Miranda, P. M., Pigrau Pastor, M., Sidani, S., et al. (2017) · Science Translational Medicine · doi:10.1126/scitranslmed.aaf6397 · Cited by 505 · see citing works

Role of precursor availability in control of monoamine biosynthesis in brain.

Fernstrom, J. D. (1983) · Physiological Reviews · doi:10.1152/physrev.1983.63.2.484 · Cited by 498 · see citing works

Redundancy, resilience, and host specificity of the ruminal microbiota: implications for engineering improved ruminal fermentations

Weimer, P. J. (2015) · Frontiers in Microbiology · doi:10.3389/fmicb.2015.00296 · Cited by 487 · see citing works

The effects of probiotics on depressive symptoms in humans: a systematic review

Wallace, C. J. K., & Milev, R. (2017) · Annals of General Psychiatry · doi:10.1186/s12991-017-0138-2 · Cited by 471 · see citing works

Short-chain fatty acids stimulate colonic transit via intraluminal 5-HT release in rats

Fukumoto, S., Tatewaki, M., Yamada, T., Fujimiya, M., Mantyh, C., Voss, M., Eubanks, S., Harris, M., Pappas, T. N., & Takahashi, T. (2003) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00442.2002 · Cited by 465 · see citing works

Bacteriocin production augments niche competition by enterococci in the mammalian gastrointestinal tract

Kommineni, S., Bretl, D. J., Lam, V., Chakraborty, R., Hayward, M., Simpson, P., Cao, Y., Bousounis, P., Kristich, C. J., & Salzman, N. H. (2015) · Nature · doi:10.1038/nature15524 · Cited by 458 · see citing works

Is eating behavior manipulated by the gastrointestinal microbiota? Evolutionary pressures and potential mechanisms

Alcock, J., Maley, C. C., & Aktipis, C. A. (2014) · BioEssays · doi:10.1002/bies.201400071 · Cited by 454 · see citing works

The gut microbiota in human energy homeostasis and obesity

Rosenbaum, M., Knight, R., & Leibel, R. L. (2015) · Trends in Endocrinology &amp; Metabolism · doi:10.1016/j.tem.2015.07.002 · Cited by 450 · see citing works

Interaction and Coevolution

Thompson, J. N. (1982) · University of Chicago Press eBooks · doi:10.7208/chicago/9780226127323.001.0001 · Cited by 445 · see citing works

Immunomodulatory mechanisms of lactobacilli

Wells, J. M. (2011) · Microbial Cell Factories · doi:10.1186/1475-2859-10-s1-s17 · Cited by 431 · see citing works

<i> <scp>B</scp> ifidobacteria </i> exert strain‐specific effects on stress‐related behavior and physiology in <scp>BALB</scp> /c mice

Savignac, H. M., Kiely, B., Dinan, T. G., & Cryan, J. F. (2014) · Neurogastroenterology &amp; Motility · doi:10.1111/nmo.12427 · Cited by 418 · see citing works

Role of the gut microbiota in host appetite control: bacterial growth to animal feeding behaviour

Fetissov, S. O. (2017) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2016.150 · Cited by 403 · see citing works

Microbial Endocrinology in the Microbiome-Gut-Brain Axis: How Bacterial Production and Utilization of Neurochemicals Influence Behavior

Lyte, M. (2013) · PLoS Pathogens · doi:10.1371/journal.ppat.1003726 · Cited by 399 · see citing works

Bacterial Neuroactive Compounds Produced by Psychobiotics

Wall, R., Cryan, J. F., Ross, R. P., Fitzgerald, G. F., Dinan, T. G., & Stanton, C. (2014) · Advances in experimental medicine and biology · doi:10.1007/978-1-4939-0897-4_10 · Cited by 362 · see citing works

The love–hate relationship between bacterial polysaccharides and the host immune system

Mazmanian, S. K., & Kasper, D. L. (2006) · Nature reviews. Immunology · doi:10.1038/nri1956 · Cited by 357 · see citing works

<scp>GABA</scp> ‐producing <i>Bifidobacterium dentium</i> modulates visceral sensitivity in the intestine

Pokusaeva, K., Johnson, C., Luk, B., Uribe, G., Fu, Y., Oezguen, N., Matsunami, R. K., Lugo, M., Major, A., Mori‐Akiyama, Y., et al. (2017) · Neurogastroenterology &amp; Motility · doi:10.1111/nmo.12904 · Cited by 337 · see citing works

Voices from within: gut microbes and the CNS

Forsythe, P., & Kunze, W. A. (2013) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-012-1028-z · Cited by 336 · see citing works

Anorexia of infection as a mechanism of host defense

Murray, M., & Murray, A. (1979) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/32.3.593 · Cited by 313 · see citing works

A Dialogue between the Immune System and Brain, Spoken in the Language of Serotonin

Baganz, N. L., & Blakely, R. (2012) · ACS Chemical Neuroscience · doi:10.1021/cn300186b · Cited by 308 · see citing works

Cooperating Commensals Restore Colonization Resistance to Vancomycin-Resistant Enterococcus faecium

Caballero, S., Kim, S., Carter, R. A., Leiner, I. M., Sušac, B., Miller, L., Kim, G. J., Ling, L., & Pamer, E. G. (2017) · Cell Host &amp; Microbe · doi:10.1016/j.chom.2017.04.002 · Cited by 308 · see citing works

The Genotypic View of Social Interactions in Microbial Communities

Mitri, S., & Foster, K. R. (2013) · Annual Review of Genetics · doi:10.1146/annurev-genet-111212-133307 · Cited by 291 · see citing works

Behavioural and neurochemical consequences of chronic gut microbiota depletion during adulthood in the rat

Hoban, A. E., Moloney, R. D., Golubeva, A. V., McVey Neufeld, K. A., O’Sullivan, O., Patterson, E., Stanton, C., Dinan, T. G., Clarke, G., & Cryan, J. F. (2016) · Neuroscience · doi:10.1016/j.neuroscience.2016.10.003 · Cited by 270 · see citing works

Behavioral mechanisms and morphological symptoms of zombie ants dying from fungal infection

Hughes, D. P., Andersen, S. B., Hywel‐Jones, N. L., Himaman, W., BILLEN, J. P. J., & Boomsma, J. J. (2011) · BMC Ecology · doi:10.1186/1472-6785-11-13 · Cited by 267 · see citing works

A molecular mechanism that stabilizes cooperative secretions in Pseudomonas aeruginosa

Xavier, J. B., Kim, W., & Foster, K. R. (2010) · Molecular Microbiology · doi:10.1111/j.1365-2958.2010.07436.x · Cited by 260 · see citing works

Do symbiotic bacteria subvert host immunity?

Hooper, L. V. (2009) · Nature Reviews Microbiology · doi:10.1038/nrmicro2114 · Cited by 256 · see citing works

Prevalence and implications of multiple-strain infections

Balmer, O., & Tanner, M. (2011) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(11)70241-9 · Cited by 256 · see citing works

Oral treatment with Lactobacillus rhamnosus attenuates behavioural deficits and immune changes in chronic social stress

Bharwani, A., Mian, M. F., Surette, M. G., Bienenstock, J., & Forsythe, P. (2017) · BMC Medicine · doi:10.1186/s12916-016-0771-7 · Cited by 236 · see citing works

The Life of a Dead Ant: The Expression of an Adaptive Extended Phenotype

Andersen, S. B., Gerritsma, S., Yusah, K. M., Mayntz, D., Hywel‐Jones, N. L., BILLEN, J. P. J., Boomsma, J. J., & Hughes, D. P. (2009) · The American Naturalist · doi:10.1086/603640 · Cited by 235 · see citing works

Bacteroides fragilis type VI secretion systems use novel effector and immunity proteins to antagonize human gut Bacteroidales species

Chatzidaki‐Livanis, M., Geva‐Zatorsky, N., & Comstock, L. E. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1522510113 · Cited by 232 · see citing works

The Evolution of Mutualism in Gut Microbiota Via Host Epithelial Selection

Schlüter, J., & Foster, K. R. (2012) · PLoS Biology · doi:10.1371/journal.pbio.1001424 · Cited by 228 · see citing works

Evolution of cell–cell signaling in animals: did late horizontal gene transfer from bacteria have a role?

Iyer, L. M., Aravind, L., Coon, S. L., Klein, D. C., & Koonin, E. V. (2004) · Trends in Genetics · doi:10.1016/j.tig.2004.05.007 · Cited by 219 · see citing works

Human symbionts inject and neutralize antibacterial toxins to persist in the gut

Wexler, A. G., Bao, Y., Whitney, J. C. C., Bobay, L., Xavier, J. B., Schofield, W. B., Barry, N. A., Russell, A. B., Tran, B. Q., Goo, Y. A., et al. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1525637113 · Cited by 216 · see citing works

Microbial Endocrinology: The Microbiota-Gut-Brain Axis in Health and Disease

Lyte, M., & Cryan, J. (2014) · Advances in Experimental Medicine and Biology · doi:10.1007/978-1-4939-0897-4 · Cited by 212 · see citing works

Parasite manipulation of the proximate mechanisms that mediate social behavior in vertebrates

Klein, S. L. (2003) · Physiology & Behavior · doi:10.1016/s0031-9384(03)00163-x · Cited by 207 · see citing works

Host Gut Motility Promotes Competitive Exclusion within a Model Intestinal Microbiota

Wiles, T. J., Jemielita, M., Baker, R. P., Schlomann, B. H., Logan, S. L., Ganz, J., Melançon, E., Eisen, J. S., Guillemin, K. J., & Parthasarathy, R. (2016) · PLoS Biology · doi:10.1371/journal.pbio.1002517 · Cited by 206 · see citing works

Debugging how Bacteria Manipulate the Immune Response

Sansonetti, P. J., & Santo, J. P. D. (2007) · Immunity · doi:10.1016/j.immuni.2007.02.004 · Cited by 197 · see citing works

Regulators of gut motility revealed by a gnotobiotic model of diet-microbiome interactions related to travel

Dey, N., Wagner, V. E., Blanton, L. V., Cheng, J., Fontana, L., Haque, R., Ahmed, T., & Gordon, J. I. (2015) · Cell · doi:10.1016/j.cell.2015.08.059 · Cited by 195 · see citing works

Mathematical modeling of primary succession of murine intestinal microbiota

Marino, S., Baxter, N. T., Huffnagle, G. B., Petrosino, J. F., & Schloss, P. D. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1311322111 · Cited by 194 · see citing works

Parasitic inhibition of cell death facilitates symbiosis

Pannebakker, B. A., Loppin, B., Elemans, C. P. H., Humblot, L., & Vavre, F. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0607845104 · Cited by 193 · see citing works

What is a pathogen? Toward a process view of host-parasite interactions

Méthot, P., & Alizon, S. (2014) · Virulence · doi:10.4161/21505594.2014.960726 · Cited by 181 · see citing works

Host Selection of Microbiota via Differential Adhesion

McLoughlin, K. G., Schlüter, J., Rakoff-Nahoum, S., Smith, A. L., & Foster, K. R. (2016) · Cell Host & Microbe · doi:10.1016/j.chom.2016.02.021 · Cited by 180 · see citing works

Bacteroides fragilis polysaccharide A is necessary and sufficient for acute activation of intestinal sensory neurons

Mao, Y.-K., Kasper, D. L., Wang, B., Forsythe, P., Bienenstock, J., & Kunze, W. A. (2013) · Nature Communications · doi:10.1038/ncomms2478 · Cited by 178 · see citing works

Modulating the Modulators: Parasites, Neuromodulators and Host Behavioral Change

Adamo, S. A. (2002) · Brain Behavior and Evolution · doi:10.1159/000067790 · Cited by 169 · see citing works

Pathogen-Mediated Inhibition of Anorexia Promotes Host Survival and Transmission

Rao, S., Schieber, A. M. P., O’Connor, C. P., Leblanc, M., Michel, D., & Ayres, J. S. (2017) · Cell · doi:10.1016/j.cell.2017.01.006 · Cited by 167 · see citing works

Parasites: evolution’s neurobiologists

Adamo, S. A. (2012) · Journal of Experimental Biology · doi:10.1242/jeb.073601 · Cited by 164 · see citing works

The Vibrio cholerae type VI secretion system can modulate host intestinal mechanics to displace gut bacterial symbionts

Logan, S. L., Thomas, J. F., Yan, J., Baker, R. P., Shields, D. S., Xavier, J. B., Hammer, B. K., & Parthasarathy, R. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1720133115 · Cited by 164 · see citing works

Lactobacillus plantarum attenuates anxiety-related behavior and protects against stress-induced dysbiosis in adult zebrafish

Davis, D. J., Doerr, H. M., Grzelak, A. K., Busi, S. B., Jašarević, E., Ericsson, A. C., & Bryda, E. C. (2016) · Scientific Reports · doi:10.1038/srep33726 · Cited by 159 · see citing works

Cooperation and conflict in host–manipulating parasites

Brown, S. P. (1999) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.1999.0864 · Cited by 157 · see citing works

Behavioural manipulation in a grasshopper harbouring hairworm: a proteomics approach

Biron, D. G., Marché, L., Ponton, F., Loxdale, H. D., Galéotti, N., RENAULT, L., Joly, C., & Frédéric Thomas, A. (2005) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2005.3213 · Cited by 155 · see citing works

The Pyromaniac Inside You: Salmonella Metabolism in the Host Gut

Rivera-Chávez, F., & Bäumler, A. J. (2015) · Annual Review of Microbiology · doi:10.1146/annurev-micro-091014-104108 · Cited by 143 · see citing works

Friends with social benefits: host-microbe interactions as a driver of brain evolution and development?

Stilling, R. M., Bordenstein, S. R., Dinan, T. G., & Cryan, J. F. (2014) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2014.00147 · Cited by 135 · see citing works

Understanding mutualism when there is adaptation to the partner

de Mazancourt, C., Loreau, M., & Dieckmann, U. (2005) · Journal of Ecology · doi:10.1111/j.0022-0477.2004.00952.x · Cited by 128 · see citing works

The hygiene hypothesis and psychiatric disorders

Rook, G. A. W., & Lowry, C. A. (2008) · Trends in Immunology · doi:10.1016/j.it.2008.01.002 · Cited by 124 · see citing works

Cooperative Microbial Tolerance Behaviors in Host-Microbiota Mutualism

Ayres, J. S. (2016) · Cell · doi:10.1016/j.cell.2016.05.049 · Cited by 109 · see citing works

Microflora Modulation of Motility

Quigley, E. M. M. (2011) · Journal of Neurogastroenterology and Motility · doi:10.5056/jnm.2011.17.2.140 · Cited by 106 · see citing works

T6SS: The bacterial "fight club" in the host gut

Sana, T. G., Lugo, K., & Monack, D. M. (2017) · PLoS Pathogens · doi:10.1371/journal.ppat.1006325 · Cited by 84 · see citing works

Iron Chelator Triggers Inflammatory Signals in Human Intestinal Epithelial Cells: Involvement of p38 and Extracellular Signal-Regulated Kinase Signaling Pathways

Choi, E., Kim, E.-C., Oh, H., Kim, S., Lee, H., Cho, E.-Y., Yoon, K., Kim, E.-A. L., Han, W., Choi, S. C., et al. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.172.11.7069 · Cited by 69 · see citing works

gamma-Aminobutyric acid uptake by a bacterial system with neurotransmitter binding characteristics.

Guthrie, G. D., & Nicholson-Guthrie, C. S. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.19.7378 · Cited by 61 · see citing works

Behavioral Microbiomics: A Multi-Dimensional Approach to Microbial Influence on Behavior

Wong, A. C.-N., Holmes, A., Ponton, F., Lihoreau, M., Wilson, K., Raubenheimer, D., & Simpson, S. J. (2015) · Frontiers in Microbiology · doi:10.3389/fmicb.2015.01359 · Cited by 61 · see citing works

Microbes can help explain the evolution of host altruism

Lewin‐Epstein, O., Aharonov, R., & Hadany, L. (2017) · Nature Communications · doi:10.1038/ncomms14040 · Cited by 58 · see citing works

The struggle for iron: gastrointestinal microbes modulate the host immune response during infection

Markel, T. A., Crisostomo, P. R., Wang, M., Herring, C. M., Meldrum, K. K., Lillemoe, K. D., & Meldrum, D. R. (2007) · Journal of Leukocyte Biology · doi:10.1189/jlb.0906579 · Cited by 57 · see citing works

Better with your parasites? Lessons for behavioural ecology from evolved dependence and conditionally helpful parasites

Weinersmith, K. L., & Earley, R. L. (2016) · Animal Behaviour · doi:10.1016/j.anbehav.2016.06.004 · Cited by 48 · see citing works

Defensive mutualisms: do microbial interactions within hosts drive the evolution of defensive traits?

May, G., & Nelson, P. (2013) · Functional Ecology · doi:10.1111/1365-2435.12166 · Cited by 47 · see citing works

Oral infection of mice with Salmonella entericaserovar Typhimurium causes meningitis and infection of the brain

Wickham, M. E., Brown, N. F., Provias, J., Finlay, B. B., & Coombes, B. K. (2007) · BMC Infectious Diseases · doi:10.1186/1471-2334-7-65 · Cited by 46 · see citing works

Investigating candidate neuromodulatory systems underlying parasitic manipulation: concepts, limitations and prospects

Perrot‐Minnot, M., & Cézilly, F. (2012) · Journal of Experimental Biology · doi:10.1242/jeb.074146 · Cited by 43 · see citing works

The brain’s Geppetto—microbes as puppeteers of neural function and behaviour?

Stilling, R. M., Dinan, T. G., & Cryan, J. F. (2015) · Journal of NeuroVirology · doi:10.1007/s13365-015-0355-x · Cited by 41 · see citing works

Symbiosis: Gut Bacteria Manipulate Host Behaviour

Yuval, B. (2017) · Current Biology · doi:10.1016/j.cub.2017.06.050 · Cited by 40 · see citing works

The evolution of host manipulation by parasites: a game theory analysis

Vickery, W. L., & Poulin, R. (2009) · Evolutionary Ecology · doi:10.1007/s10682-009-9334-0 · Cited by 38 · see citing works

Pleiotropy and the low cost of individual traits promote cooperation

Mitri, S., & Foster, K. R. (2016) · Evolution · doi:10.1111/evo.12851 · Cited by 29 · see citing works

Regulatory Influences on the Production of Gamma-Aminobutyric Acid by a Marine Pseudomonad

Mountfort, D. O., & Pybus, V. (1992) · Applied and Environmental Microbiology · doi:10.1128/aem.58.1.237-242.1992 · Cited by 16 · see citing works

Do all parasites manipulate their hosts?

Brown, S. P. (2005) · Behavioural Processes · doi:10.1016/j.beproc.2004.08.015 · Cited by 11 · see citing works

Carbohydrate-active enzymes (CAZymes) in the gut microbiome

Wardman, J. F., Bains, R. K., Rahfeld, P., & Withers, S. G. (2022) · Nature Reviews Microbiology · doi:10.1038/s41579-022-00712-1 · Cited by 597 · see citing works

Gut Microbiota and Energy Homeostasis in Fish

Butt, R. L., & Volkoff, H. (2019) · Frontiers in Endocrinology · doi:10.3389/fendo.2019.00009 · Cited by 621 · see citing works

Microglia and Central Nervous System–Associated Macrophages—From Origin to Disease Modulation

Prinz, M., Masuda, T., Wheeler, M. A., & Quintana, F. J. (2021) · Annual Review of Immunology · doi:10.1146/annurev-immunol-093019-110159 · Cited by 584 · see citing works

Host–microbiota interactions in immune-mediated diseases

Ruff, W. E., Greiling, T. M., & Kriegel, M. A. (2020) · Nature Reviews Microbiology · doi:10.1038/s41579-020-0367-2 · Cited by 489 · see citing works

Antibiotics, gut microbiota, and Alzheimer’s disease

Angelucci, F., Cechova, K., Amlerova, J., & Hort, J. (2019) · Journal of Neuroinflammation · doi:10.1186/s12974-019-1494-4 · Cited by 454 · see citing works

The Microbiota–Gut–Brain Axis and Alzheimer’s Disease: Neuroinflammation Is to Blame?

Megur, A., Baltriukienė, D., Bukelskienė, V., & Burokas, A. (2020) · Nutrients · doi:10.3390/nu13010037 · Cited by 323 · see citing works

Inflammation and Neuro-Immune Dysregulations in Autism Spectrum Disorders

Siniscalco, D., Schultz, S. T., Brigida, A. L., & Antonucci, N. (2018) · Pharmaceuticals · doi:10.3390/ph11020056 · Cited by 306 · see citing works

Bacteriocin-Producing Probiotic Lactic Acid Bacteria in Controlling Dysbiosis of the Gut Microbiota

Anjana, A., & Tiwari, S. K. (2022) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2022.851140 · Cited by 272 · see citing works

The microbiota and the hypothalamus-pituitary-adrenocortical (HPA) axis, implications for anxiety and stress disorders

Frankiensztajn, L. M., Elliott, E., & Koren, O. (2020) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2019.12.003 · Cited by 248 · see citing works

Hydrogen sulfide toxicity in the gut environment: Meta-analysis of sulfate-reducing and lactic acid bacteria in inflammatory processes

Đorđević, Đ., Jančíková, S., Vítězová, M., & Kushkevych, I. V. (2020) · Journal of Advanced Research · doi:10.1016/j.jare.2020.03.003 · Cited by 248 · see citing works

Gut microbiota drives age-related oxidative stress and mitochondrial damage in microglia via the metabolite N6-carboxymethyllysine

Mossad, O., Batut, B., Yilmaz, B., Dokalis, N., Mezö, C., Nent, E., Nabavi, L. S., Mayer, M., Maron, F. J. M., Buescher, J. M., et al. (2022) · Nature Neuroscience · doi:10.1038/s41593-022-01027-3 · Cited by 241 · see citing works

Gut microbiome composition and diversity are related to human personality traits

Johnson, K. V. ‐. (2019) · Human Microbiome Journal · doi:10.1016/j.humic.2019.100069 · Cited by 241 · see citing works

Gut Microbiota and Their Neuroinflammatory Implications in Alzheimer’s Disease

Giau, V. V., Wu, S., Jamerlan, A., An, S. S. A., Kim, S., & Hulme, J. (2018) · Nutrients · doi:10.3390/nu10111765 · Cited by 235 · see citing works

Microbial transmission in animal social networks and the social microbiome

Sarkar, A., Harty, S., Johnson, K. V. ‐., Moeller, A. H., Archie, E. A., Schell, L. D., Carmody, R. N., Clutton-Brock, T. H., Dunbar, R., & Burnet, P. W. J. (2020) · Nature Ecology & Evolution · doi:10.1038/s41559-020-1220-8 · Cited by 220 · see citing works

Emerging role of gut microbiota in modulation of neuroinflammation and neurodegeneration with emphasis on Alzheimer's disease

Goyal, D., Ali, S. A., & Singh, R. K. (2020) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2020.110112 · Cited by 208 · see citing works

Gut dysbiosis, defective autophagy and altered immune responses in neurodegenerative diseases: Tales of a vicious cycle

Chidambaram, S. B., Essa, M. M., Rathipriya, A. G., Bishir, M., Ray, B., Mahalakshmi, A. M., Tousif, A. H., Sakharkar, M. K., Kashyap, R. S., Friedland, R. P., et al. (2022) · Pharmacology &amp; Therapeutics · doi:10.1016/j.pharmthera.2021.107988 · Cited by 204 · see citing works

The role of gut microbiota in pathogenesis of Alzheimer's disease

Bostancıklıoğlu, M. (2019) · Journal of Applied Microbiology · doi:10.1111/jam.14264 · Cited by 200 · see citing works

Nanoplastic ingestion induces behavioral disorders in terrestrial snails: trophic transfer effects via vascular plants

Chae, Y., & An, Y. (2020) · Environmental Science Nano · doi:10.1039/c9en01335k · Cited by 194 · see citing works

Mechanisms underlying gut microbiota–host interactions in insects

Schmidt, K., & Engel, P. (2021) · Journal of Experimental Biology · doi:10.1242/jeb.207696 · Cited by 176 · see citing works

Horizontal gene transfer among host-associated microbes

de Sousa, J. A. M., Lourenço, M., & Gordo, I. (2023) · Cell Host & Microbe · doi:10.1016/j.chom.2023.03.017 · Cited by 170 · see citing works

Role of gut microbiota via the gut-liver-brain axis in digestive diseases

Ding, J., Jin, Z., Yang, X., Lou, J., Shan, W., Hu, Y., Du, Q., Liao, Q., Xie, R., & Xu, J. (2020) · World Journal of Gastroenterology · doi:10.3748/wjg.v26.i40.6141 · Cited by 172 · see citing works

Gut microbiota and pro/prebiotics in Alzheimer’s disease

Pluta, R. M., Ułamek-Kozioł, M., Januszewski, S., & Czuczwar, S. J. (2020) · Aging · doi:10.18632/aging.102930 · Cited by 171 · see citing works

Psychological comorbidity in gastrointestinal diseases: Update on the brain-gut-microbiome axis

Person, H., & Keefer, L. (2021) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2020.110209 · Cited by 158 · see citing works

Microbiota‐gut‐brain axis as a regulator of reward processes

García‐Cabrerizo, R., Carbia, C., O’Riordan, K. J., Schellekens, H., & Cryan, J. F. (2020) · Journal of Neurochemistry · doi:10.1111/jnc.15284 · Cited by 147 · see citing works

The Gut and Parkinson's Disease—A Bidirectional Pathway

Santos, S. F., de Oliveira, H. L., Yamada, E. S., Neves, B. C., & Pereira, A. (2019) · Frontiers in Neurology · doi:10.3389/fneur.2019.00574 · Cited by 144 · see citing works

The role of the microbiome in the neurobiology of social behaviour

Sarkar, A., Harty, S., Johnson, K. V. ‐., Moeller, A. H., Carmody, R. N., Lehto, S. M., Erdman, S. E., Dunbar, R. I. M., & Burnet, P. W. J. (2020) · Biological Reviews · doi:10.1111/brv.12603 · Cited by 135 · see citing works

Microbial transmission in the social microbiome and host health and disease

Sarkar, A., McInroy, C. J. A., Harty, S., Raulo, A., Ibata, N. G. O., Valles‐Colomer, M., Johnson, K. V. ‐., Brito, I., Henrich, J., Archie, E. A., et al. (2024) · Cell · doi:10.1016/j.cell.2023.12.014 · Cited by 130 · see citing works

The gut microbiome defines social group membership in honey bee colonies

Vernier, C., Chin, I. M., Adu‐Oppong, B., Krupp, J. J., Levine, J. D., Dantas, G. A., & Ben‐Shahar, Y. (2020) · Science Advances · doi:10.1126/sciadv.abd3431 · Cited by 123 · see citing works

The Gut-Brain Axis: Two Ways Signaling in Parkinson’s Disease

Dogra, N., Mani, R. J., & Katare, D. P. (2021) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-021-01066-7 · Cited by 117 · see citing works

Pharmacogenomics‐Driven Prediction of Antidepressant Treatment Outcomes: A Machine‐Learning Approach With Multi‐trial Replication

Athreya, A. P., Neavin, D. R., Carrillo‐Roa, T., Skime, M. K., Biernacka, J. M., Frye, M. A., Rush, A. J., Wang, L., Binder, E. B., Iyer, R. K., et al. (2019) · Clinical Pharmacology & Therapeutics · doi:10.1002/cpt.1482 · Cited by 114 · see citing works

A wireless, implantable optoelectrochemical probe for optogenetic stimulation and dopamine detection

Liu, C., Zhao, Y., Cai, X., Xie, Y., Wang, T., Cheng, D., Li, L., Li, R., Deng, Y., Ding, H., et al. (2020) · Microsystems & Nanoengineering · doi:10.1038/s41378-020-0176-9 · Cited by 111 · see citing works

Disentangling host–microbiota complexity through hologenomics

Alberdi, A., Andersen, S. B., Limborg, M. T., Dunn, R. R., & Gilbert, M. T. P. (2021) · Nature Reviews Genetics · doi:10.1038/s41576-021-00421-0 · Cited by 103 · see citing works

The gut microbiota — brain axis of insects

Liberti, J., & Engel, P. (2020) · Current Opinion in Insect Science · doi:10.1016/j.cois.2020.01.004 · Cited by 104 · see citing works

Adverse Reactions to Wheat or Wheat Components

Brouns, F. J. P. H., van Rooy, G., Shewry, P. R., Rustgi, S., & Jonkers, D. M. A. E. (2019) · Comprehensive Reviews in Food Science and Food Safety · doi:10.1111/1541-4337.12475 · Cited by 109 · see citing works

Can Gut Microbiota Affect Dry Eye Syndrome?

Moon, J., Yoon, C. H., Choi, S. H., & Kim, M. K. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21228443 · Cited by 98 · see citing works

Microbiota-gut-brain research: A critical analysis

Hooks, K. B., Konsman, J. P., & O’Malley, M. A. (2018) · Behavioral and Brain Sciences · doi:10.1017/s0140525x18002133 · Cited by 101 · see citing works

Walnut‐Derived Peptide PW5 Ameliorates Cognitive Impairments and Alters Gut Microbiota in APP/PS1 Transgenic Mice

Wang, M., Amakye, W. K., Guo, L., Gong, C., Zhao, Y., Yao, M., & Ren, J. (2019) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201900326 · Cited by 99 · see citing works

Alcohol-Associated Tissue Injury: Current Views on Pathophysiological Mechanisms

Simon, L., Souza‐Smith, F. M., & Molina, P. E. (2022) · Annual Review of Physiology · doi:10.1146/annurev-physiol-060821-014008 · Cited by 97 · see citing works

The gut microbiota affects the social network of honeybees

Liberti, J., Kay, T., Quinn, A., Kesner, L., Frank, E. T., Cabirol, A., Richardson, T. O., Engel, P., & Keller, L. (2022) · Nature Ecology & Evolution · doi:10.1038/s41559-022-01840-w · Cited by 98 · see citing works

Roles of gut microbiome in epilepsy risk: A Mendelian randomization study

Zeng, Y., Cao, S., & Yang, H. (2023) · Frontiers in Microbiology · doi:10.3389/fmicb.2023.1115014 · Cited by 97 · see citing works

The what, how and why of archaeological coprolite analysis

Shillito, L., Blong, J. C., Green, E. J., & van Asperen, E. N. (2020) · Earth-Science Reviews · doi:10.1016/j.earscirev.2020.103196 · Cited by 95 · see citing works

Identifying Microbiome-Mediated Behaviour in Wild Vertebrates

Davidson, G. L., Raulo, A., & Knowles, S. C. L. (2020) · Trends in Ecology & Evolution · doi:10.1016/j.tree.2020.06.014 · Cited by 95 · see citing works

The gut-eye-lacrimal gland-microbiome axis in Sjögren Syndrome

Trujillo-Vargas, C. M., Schaefer, L., Alam, J., Pflugfelder, S. C., Britton, R. A., & de Paiva, C. S. (2019) · The Ocular Surface · doi:10.1016/j.jtos.2019.10.006 · Cited by 87 · see citing works

Gut microbiome-derived lactate promotes to anxiety-like behaviors through GPR81 receptor-mediated lipid metabolism pathway

Shan, B., Ai, Z., Zeng, S., Song, Y., Song, J., Zeng, Q., Liao, Z., Wang, T., Huang, C. C., & Su, D. (2020) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2020.104699 · Cited by 86 · see citing works

Gut dysbiosis and age-related neurological diseases; an innovative approach for therapeutic interventions

Holmes, A., Finger, C. E., Morales‐Scheihing, D., Lee, J., & McCullough, L. D. (2020) · Translational research · doi:10.1016/j.trsl.2020.07.012 · Cited by 87 · see citing works

Priming for welfare: gut microbiota is associated with equitation conditions and behavior in horse athletes

Mach, N., Ruet, A., Clark, A. P., Bars‐Cortina, D., Ramayo‐Caldas, Y., Crisci, E., Pennarun, S., Dhorne‐Pollet, S., Foury, A., Moisan, M., et al. (2020) · Scientific Reports · doi:10.1038/s41598-020-65444-9 · Cited by 76 · see citing works

Gut Microbiota and Bone Diseases: A Growing Partnership

Chen, Y., Wang, X., Zhang, C., Liu, Z., Li, C., & Ren, Z. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.877776 · Cited by 81 · see citing works

Dietary sodium butyrate supplementation improves fish growth, intestinal microbiota composition, and liver health in largemouth bass (Micropterus salmoides) fed high-fat diets

Chen, W., Gao, S., Chang, K., Zhao, X., & Niu, B. (2022) · Aquaculture · doi:10.1016/j.aquaculture.2022.739040 · Cited by 78 · see citing works

Gut microbiome drives individual memory variation in bumblebees

Li, L., Solvi, C., Zhang, F., Qi, Z., Chıttka, L., & Zhao, W. (2021) · Nature Communications · doi:10.1038/s41467-021-26833-4 · Cited by 77 · see citing works

The gut microbiome in disorders of gut–brain interaction

Kraïmi, N., Ross, T., Pujo, J., & Palma, G. D. (2024) · Gut Microbes · doi:10.1080/19490976.2024.2360233 · Cited by 86 · see citing works

Microbiome Gut-Brain-Axis: Impact on Brain Development and Mental Health

Ramadan, Y. N., Alqifari, S. F., Alshehri, K., Alhowiti, A., Mirghani, H. O., Alrasheed, T., Aljohani, F., Alghamdi, A. M., & Hetta, ‏. F. (2025) · Molecular Neurobiology · doi:10.1007/s12035-025-04846-0 · Cited by 90 · see citing works

A Developing Symbiosis: Enabling Cross-Talk Between Ecologists and Microbiome Scientists

Tipton, L., Darcy, J. L., & Hynson, N. A. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.00292 · Cited by 77 · see citing works

Large‐scale functional network connectivity mediate the associations of gut microbiota with sleep quality and executive functions

Cai, H., Wang, C., Qian, Y., Zhang, S., Zhang, C., Zhao, W., Zhang, T., Zhang, B., Chen, J., Liu, S., et al. (2021) · Human Brain Mapping · doi:10.1002/hbm.25419 · Cited by 74 · see citing works

Lactobacillus rhamnosus GG colonization in early life regulates gut-brain axis and relieves anxiety-like behavior in adulthood

Zhou, B., Jin, G., Pang, X., Mo, Q., Bao, J., Liu, T., Wu, J., Xie, R., Liu, X., Liu, J., et al. (2022) · Pharmacological Research · doi:10.1016/j.phrs.2022.106090 · Cited by 77 · see citing works

The physiology of movement

Goosens, S., Wybouw, N., Leeuwen, T. V., & Bonte, D. (2020) · Movement Ecology · doi:10.1186/s40462-020-0192-2 · Cited by 74 · see citing works

Natural selection for imprecise vertical transmission in host–microbiota systems

Bruijning, M., Henry, L. P., Forsberg, S. K. G., Metcalf, C. J. E., & Ayroles, J. F. (2021) · Nature Ecology & Evolution · doi:10.1038/s41559-021-01593-y · Cited by 73 · see citing works

Gastrointestinal (GI) Tract Microbiome-Derived Neurotoxins—Potent Neuro-Inflammatory Signals From the GI Tract via the Systemic Circulation Into the Brain

Lukiw, W. J. (2020) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2020.00022 · Cited by 72 · see citing works

Probiotic Bifidobacterium breve Prevents Memory Impairment Through the Reduction of Both Amyloid-β Production and Microglia Activation in APP Knock-In Mouse

Abdelhamid, M., Zhou, C., Ohno, K., Kuhara, T., Taslima, F., Abdullah, M., Jung, C.-G., & Michikawa, M. (2021) · Journal of Alzheimer s Disease · doi:10.3233/jad-215025 · Cited by 73 · see citing works

Probiotics for the treatment of depression and its comorbidities: A systemic review

Gao, J., Zhao, N., Cheng, Y., Lei, W., Wang, Y., Liu, X., Zheng, N., Shao, L., Chen, X., Sun, Y., et al. (2023) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2023.1167116 · Cited by 75 · see citing works

A perspective on green, blue, and grey spaces, biodiversity, microbiota, and human health

Potter, J. D., Brooks, C., Donovan, G. H., Cunningham, C. W., & Douwes, J. E. (2023) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2023.164772 · Cited by 71 · see citing works

Cooperation and Conflict Within the Microbiota and Their Effects On Animal Hosts

Figueiredo, A. R. T., & Kramer, J. (2020) · Frontiers in Ecology and Evolution · doi:10.3389/fevo.2020.00132 · Cited by 61 · see citing works

Probiotics, prebiotics and postbiotics for better sleep quality: a narrative review

Haarhuis, J. E., Kardinaal, A. F. M., & Kortman, G. A. M. (2022) · Beneficial Microbes · doi:10.3920/bm2021.0122 · Cited by 63 · see citing works

Target Dysbiosis of Gut Microbes as a Future Therapeutic Manipulation in Alzheimer’s Disease

Zhu, F., Li, C., Chu, F., Tian, X., & Zhu, J. (2020) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2020.544235 · Cited by 58 · see citing works

Transmission efficiency drives host–microbe associations

Leftwich, P. T., Edgington, M. P., & Chapman, T. (2020) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2020.0820 · Cited by 57 · see citing works

Gut microbiota resilience in horse athletes following holidays out to pasture

Mach, N., Lansade, L., Bars‐Cortina, D., Dhorne‐Pollet, S., Foury, A., Moisan, M., & Ruet, A. (2021) · Scientific Reports · doi:10.1038/s41598-021-84497-y · Cited by 55 · see citing works

Multimodal neuroimaging fusion biomarkers mediate the association between gut microbiota and cognition

Zhu, J., Wang, C., Qian, Y., Cai, H., Zhang, S., Zhang, C., Zhao, W., Zhang, T., Zhang, B., Chen, J., et al. (2021) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2021.110468 · Cited by 50 · see citing works

Tissue-wide metabolomics reveals wide impact of gut microbiota on mice metabolite composition

Zarei, I., Koistinen, V., Kokla, M., Klåvus, A., Babu, A. F., Lehtonen, M., Auriola, S. O. K., & Hanhineva, K. (2022) · Scientific Reports · doi:10.1038/s41598-022-19327-w · Cited by 47 · see citing works

The Gut Microbiome in Bipolar Disorder and Pharmacotherapy Management

Flowers, S. A., Ward, K. M., & Clark, C. T. (2019) · Neuropsychobiology · doi:10.1159/000504496 · Cited by 50 · see citing works

Melatonin as a Mediator of the Gut Microbiota–Host Interaction: Implications for Health and Disease

Bonmatí‐Carrión, M., & Rol, M. A. (2023) · Antioxidants · doi:10.3390/antiox13010034 · Cited by 54 · see citing works

Evaluation of non‐lethal gut microbiome sampling methods in a passerine bird

Berlow, M., Kohl, K. D., & Derryberry, E. P. (2019) · Ibis · doi:10.1111/ibi.12807 · Cited by 48 · see citing works

Framing the discussion of microorganisms as a facet of social equity in human health

Ishaq, S. L., Rapp, M., Byerly, R., McClellan, L. S., O’Boyle, M. R., Nykanen, A., Fuller, P. J., Aas, C., Stone, J. M., Killpatrick, S., et al. (2019) · PLoS Biology · doi:10.1371/journal.pbio.3000536 · Cited by 47 · see citing works

Gut microbiota in ALS: possible role in pathogenesis?

McCombe, P. A., Henderson, R. D., Lee, A., Lee, J. D., Woodruff, T. M., Restuadi, R., McRae, A., Wray, N. R., Ngo, S., & Steyn, F. J. (2019) · Expert Review of Neurotherapeutics · doi:10.1080/14737175.2019.1623026 · Cited by 46 · see citing works

Fish Gut Microbiome: A Primer to an Emerging Discipline in the Fisheries Sciences

Gallo, B. D., Farrell, J. M., & Leydet, B. F. (2019) · Fisheries · doi:10.1002/fsh.10379 · Cited by 46 · see citing works

Gut Microbial Characteristics of Adult Patients With Epilepsy

Dong, L., Zheng, Q., Cheng, Y., Zhou, M., Wang, M., Xu, J., Xu, Z., Wu, G., Yu, Y., Ye, L., et al. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.803538 · Cited by 45 · see citing works

The gut microbiome variability of a butterflyfish increases on severely degraded Caribbean reefs

Clever, F., Sourisse, J. M., Preziosi, R. F., Eisen, J. A., Guerra, E. C. R., Scott, J. J., Wilkins, L. G. E., Altieri, A. H., McMillan, W. O., & Leray, M. (2022) · Communications Biology · doi:10.1038/s42003-022-03679-0 · Cited by 45 · see citing works

Effects of starvation and subsequent re-feeding on intestinal microbiota, and metabolic responses in Nile tilapia, Oreochromis niloticus

Sakyi, M. E., Cai, J. X., Tang, J., Abarike, E. D., Xia, L., Li, P., Kuebutornye, F. K. A., Zou, Z., Liang, Z., & Jian, J. (2020) · Aquaculture Reports · doi:10.1016/j.aqrep.2020.100370 · Cited by 45 · see citing works

Microbial Glycoside Hydrolases in the First Year of Life: An Analysis Review on Their Presence and Importance in Infant Gut

Ioannou, A., Knol, J., & Belzer, C. (2021) · Frontiers in Microbiology · doi:10.3389/fmicb.2021.631282 · Cited by 44 · see citing works

Anthocyanins from Lycium ruthenicum Murray Ameliorated High-Fructose Diet-Induced Neuroinflammation through the Promotion of the Integrity of the Intestinal Barrier and the Proliferation of Lactobacillus

Peng, Y., Dong, W., Chen, G., Mi, J., Lu, L., Xie, Z., Xu, W., Zhou, W., Sun, Y., Zeng, X., et al. (2023) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.2c06713 · Cited by 46 · see citing works

Social and population health science approaches to understand the human microbiome

Herd, P., Palloni, A., Rey, F. E., & Dowd, J. B. (2018) · Nature Human Behaviour · doi:10.1038/s41562-018-0452-y · Cited by 45 · see citing works

Why do some fish grow faster than others?

Goodrich, H. R., & Clark, T. D. (2023) · Fish and Fisheries · doi:10.1111/faf.12770 · Cited by 44 · see citing works

I’ve Gut A Feeling: Microbiota Impacting the Conceptual and Experimental Perspectives of Personalized Medicine

Amedei, A., & Boem, F. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19123756 · Cited by 43 · see citing works

A Biopsychosocial Overview of the Opioid Crisis: Considering Nutrition and Gastrointestinal Health

Wiss, D. A. (2019) · Frontiers in Public Health · doi:10.3389/fpubh.2019.00193 · Cited by 41 · see citing works

Origin of Mutualism Between Termites and Flagellated Gut Protists: Transition From Horizontal to Vertical Transmission

Nalepa, C. A. (2020) · Frontiers in Ecology and Evolution · doi:10.3389/fevo.2020.00014 · Cited by 42 · see citing works

The impact of the gut microbiome on memory and sleep in Drosophila

Silva, V., Palacios-Muñoz, A., Okray, Z., Adair, K. L., Waddell, S., Douglas, A. E., & Ewer, J. (2020) · Journal of Experimental Biology · doi:10.1242/jeb.233619 · Cited by 42 · see citing works

Why Evolve Reliance on the Microbiome for Timing of Ontogeny?

Metcalf, C. J. E., Henry, L. P., Rebolleda‐Gómez, M., & Koskella, B. L. (2019) · mBio · doi:10.1128/mbio.01496-19 · Cited by 36 · see citing works

Infections, inflammation, and risk of neuropsychiatric disorders: the neglected role of “co-infection”

Abdoli, A., Taghipour, A., Pirestani, M., Jahromi, M. A. M., Roustazadeh, A., Mir, H., Ardakani, H. M., Kenarkoohi, A., Falahi, S., & Karimi, M. (2020) · Heliyon · doi:10.1016/j.heliyon.2020.e05645 · Cited by 38 · see citing works

Modulation of the gut–brain axis via the gut microbiota: a new era in treatment of amyotrophic lateral sclerosis

Hong, D., Zhang, C., Wu, W., Lu, X., & Zhang, L. (2023) · Frontiers in Neurology · doi:10.3389/fneur.2023.1133546 · Cited by 38 · see citing works

The ketogenic diet: its impact on human gut microbiota and potential consequent health outcomes: a systematic literature review.

Rew, L., Harris, M. D., & Goldie, J. H. (2022) · Gastroenterology and hepatology from bed to bench. · doi:10.22037/ghfbb.v15i4.2600 · Cited by 43 · see citing works

Multidisciplinary and Comparative Investigations of Potential Psychobiotic Effects of Lactobacillus Strains Isolated From Newborns and Their Impact on Gut Microbiota and Ileal Transcriptome in a Healthy Murine Model

Beck, B. R., Park, G.-S., Jeong, D. Y., Lee, Y. H., Im, S., Song, W. H., & Kang, J. (2019) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2019.00269 · Cited by 38 · see citing works

The relationship between gut microbiota and insomnia: a bi-directional two-sample Mendelian randomization research

Yan, L., Deng, Q., & Liu, Z. (2023) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2023.1296417 · Cited by 37 · see citing works

Implications of Microorganisms in Alzheimer’s Disease

Yadav, P., Lee, Y., Panday, H., Kant, S., Bajwa, N., Parashar, R., Jha, S. K., Jha, N. K., Nand, P., Lee, S., et al. (2022) · Current Issues in Molecular Biology · doi:10.3390/cimb44100314 · Cited by 37 · see citing works

How gut microbiota may impact ocular surface homeostasis and related disorders

Labétoulle, M., Baudouin, C., del Castillo, J. M. B., Rolando, M., Rescigno, M., Messmer, E. S. B. M., & Aragona, P. (2024) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2024.101250 · Cited by 37 · see citing works

Cooperation and cheating orchestrate Vibrio assemblages and polymicrobial synergy in oysters infected with OsHV-1 virus

Oyanedel, D., Lagorce, A., Bruto, M., Haffner, P., Morot, A., Labreuche, Y., Dorant, Y., Divonne, S. D. L. F., Delavat, F., Inguimbert, N., et al. (2023) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2305195120 · Cited by 34 · see citing works

Some Candidate Drugs for Pharmacotherapy of Alzheimer’s Disease

Miziak, B., Błaszczyk, B., & Czuczwar, S. J. (2021) · Pharmaceuticals · doi:10.3390/ph14050458 · Cited by 35 · see citing works

Sociability in a non-captive macaque population is associated with beneficial gut bacteria

Johnson, K. V. ‐., Watson, K. K., Dunbar, R., & Burnet, P. W. J. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.1032495 · Cited by 34 · see citing works

The Lovebug Effect: Is the human biophilic drive influenced by interactions between the host, the environment, and the microbiome?

Robinson, J. M., & Breed, M. F. (2020) · Science of The Total Environment · doi:10.1016/j.scitotenv.2020.137626 · Cited by 30 · see citing works

Leveraging non-human primates for exploring the social transmission of microbes

Kuthyar, S., Manus, M. B., & Amato, K. R. (2019) · Current Opinion in Microbiology · doi:10.1016/j.mib.2019.09.001 · Cited by 32 · see citing works

Opposing effects of antibiotics and germ-free status on neuropeptide systems involved in social behaviour and pain regulation

Johnson, K. V. ‐., & Burnet, P. W. J. (2020) · BMC Neuroscience · doi:10.1186/s12868-020-00583-3 · Cited by 31 · see citing works

The Gut Microbial Composition Is Species-Specific and Individual-Specific in Two Species of Estrildid Finches, the Bengalese Finch and the Zebra Finch

Maracı, Ö., Antonatou-Papaioannou, A., Jünemann, S., Castillo-Gutiérrez, O., Busche, T., Kalinowski, J., & Caspers, B. A. (2021) · Frontiers in Microbiology · doi:10.3389/fmicb.2021.619141 · Cited by 31 · see citing works

How Diet and Lifestyle Can Fine-Tune Gut Microbiomes for Healthy Aging

Tamayo, M., Olivares, M., Ruas‐Madiedo, P., Margollés, A., Espı́n, J. C., Medina, I., Moreno-Arribas, M. V., Canals, S., Mirasso, C. R., Ortín, S., et al. (2024) · Annual Review of Food Science and Technology · doi:10.1146/annurev-food-072023-034458 · Cited by 33 · see citing works

Microorganisms that Manipulate Complex Animal Behaviours by Affecting the Host’s Nervous System

Rohrscheib, C. E., & Jeremy, B. (2013) · Springer Science Reviews · doi:10.1007/s40362-013-0013-8 · Cited by 24 · see citing works

Relationship between the gut microbiome and behaviour at the molecular, organism, population and evolutionary levels

Johnson, K. V. ‐. (2018) · Oxford University Research Archive (ORA) (University of Oxford) · doi:10.5287/ora-gjmjarqez

Identifying Microbiome-Mediated Behaviour in Wild Vertebrates.

Davidson, G. L., Raulo, A., & Knowles, S. C. L. (2020) · Apollo (University of Cambridge) · doi:10.17863/cam.55785

Insect behaviour and the microbiome

Lewis, Z., & Lizé, A. (2015) · Current Opinion in Insect Science · doi:10.1016/j.cois.2015.03.003 · Cited by 93 · see citing works

A Microbial Community Ecology Perspective on the Gut-Microbiome-Brain Axis

van der Goot, E., van Spronsen, F. J., Salles, J. F., & van der Zee, E. A. (2020) · Frontiers in Endocrinology · doi:10.3389/fendo.2020.00611 · Cited by 9 · see citing works