Cited by 355

The DOI matches its Crossref record; 224 of the 224 references it cites were found in a registry or an index.

Quorum sensing and bacterial biofilms

Dickschat, Jeroen S.·2010·Natural Product Reports

Open this paper in CoChat — free account

Abstract

This review describes the chemistry of the bacterial biofilms including the chemistry of their constituents and signalling compounds that mediate or inhibit the formation of biofilms. Systems are described with special emphasis, in which quorum sensing molecules (autoinducers) trigger the formation of biofilms. In the first instance, N-acyl-L-homoserine lactones (AHLs) are the focus of this review, whereas the inter-species signal known as furanosyl borate diester and peptide autoinducers used by Gram-positive bacteria are not discussed in detail. Since the first discovery of an AHL autoinducer from Vibrio fischeri a large and further increasing number of different AHL structures from Gram-negative bacteria have been identified. This review gives a summary of all known AHL autoinducers and producing bacterial species. A few systems are discussed, where biofilm formation is suppressed by enzymatic degradation of AHL molecules or interference of secondary metabolites from other species with the quorum sensing systems of communicating bacteria. Finally, the multi-channel quorum sensing system, the intracellular downstream processing of the signal, and the resulting response of whole populations including biofilm formation are discussed for the Vibrio genus that has been extensively investigated.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1039/b804469b

Cites

224 of 224 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

1 retracted

RETRACTED: Cell–cell signaling in Xanthomonas campestris involves an HD-GYP domain protein that functions in cyclic di-GMP turnover
Ryan, R. P., Fouhy, Y., Lucey, J. F., Crossman, L. C., Spiro, S., He, Y.-W., Zhang, L.-H., Heeb, S., Cámara, M., Williams, P., et al. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0600345103 · Cited by 507
Retracted
Bacterial Biofilms: A Common Cause of Persistent Infections
Costerton, J. W., Stewart, P. S., & Greenberg, E. P. (1999) · Science · doi:10.1126/science.284.5418.1318 · Cited by 12,167
The Involvement of Cell-to-Cell Signals in the Development of a Bacterial Biofilm
Davies, D. G., Parsek, M. R., Pearson, J. P., Iglewski, B. H., Costerton, J. W., & Greenberg, E. P. (1998) · Science · doi:10.1126/science.280.5361.295 · Cited by 3,396
Extracellular DNA Required for Bacterial Biofilm Formation
Whitchurch, C. B., Tolker-Nielsen, T., Ragas, P. C., & Mattick, J. S. (2002) · Science · doi:10.1126/science.295.5559.1487 · Cited by 2,203
DNA sequence of both chromosomes of the cholera pathogen Vibrio cholerae
Heidelberg, J. F., Eisen, J. A., Nelson, W. C., Clayton, R. A., Gwinn, M. L., Dodson, R. J., Haft, D. H., Hickey, E. K., Peterson, J. D., Umayam, L., et al. (2000) · Nature · doi:10.1038/35020000 · Cited by 1,870
Microbial pathogenesis in cystic fibrosis: mucoid Pseudomonas aeruginosa and Burkholderia cepacia
Govan, J. R. W., & Deretic, V. P. (1996) · Microbiological Reviews · doi:10.1128/mmbr.60.3.539-574.1996 · Cited by 1,812
Quorum sensing and Chromobacterium violaceum: exploitation of violacein production and inhibition for the detection of N-acylhomoserine lactones
McClean, K. H., Winson, M. K., Fish, L., Taylor, A., Chhabra, S. R., Camara, M., Daykin, M., Lamb, J. H., Swift, S., Bycroft, B. W., et al. (1997) · Microbiology · doi:10.1099/00221287-143-12-3703 · Cited by 1,744
Structural identification of a bacterial quorum-sensing signal containing boron
Chen, X., Schauder, S., Potier, N., Van Dorsselaer, A., Pelczer, I., Bassler, B. L., & Hughson, F. M. (2002) · Nature · doi:10.1038/415545a · Cited by 1,571
Quorum-sensing signals indicate that cystic fibrosis lungs are infected with bacterial biofilms
Singh, P. K., Schaefer, A. L., Parsek, M. R., Moninger, T. O., Welsh, M. J., & Greenberg, E. P. (2000) · Nature · doi:10.1038/35037627 · Cited by 1,519
Biodiversity of Vibrios
Thompson, F. L., Iida, T., & Swings, J. (2004) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.68.3.403-431.2004 · Cited by 1,240
A characterization of DNA release in Pseudomonas aeruginosa cultures and biofilms
Allesen‐Holm, M., Barken, K. B., Yang, L., Klausen, M., Webb, J. S., Kjelleberg, S., Molin, S., Givskov, M., & Tolker‐Nielsen, T. (2006) · Molecular Microbiology · doi:10.1111/j.1365-2958.2005.05008.x · Cited by 1,086
Quenching quorum-sensing-dependent bacterial infection by an N-acyl homoserine lactonase
Dong, Y.-H., Wang, L.-H., Xu, J.-L., Zhang, H.-B., Zhang, X.-F., & Zhang, L.-H. (2001) · Nature · doi:10.1038/35081101 · Cited by 1,064
Genome sequence of Vibrio parahaemolyticus: a pathogenic mechanism distinct from that of V cholerae
Makino, K., Oshima, K., Kurokawa, K., Yokoyama, K., Uda, T., Tagomori, K., Iijima, Y., Najima, M., Nakano, M., Yamashita, A., et al. (2003) · The Lancet · doi:10.1016/s0140-6736(03)12659-1 · Cited by 1,042
The LuxS family of bacterial autoinducers: biosynthesis of a novel quorum‐sensing signal molecule
Schauder, S., Shokat, K., Surette, M. G., & Bassler, B. L. (2001) · Molecular Microbiology · doi:10.1046/j.1365-2958.2001.02532.x · Cited by 1,035
An Elicitor of Plant Volatiles from Beet Armyworm Oral Secretion
Alborn, H. T., Turlings, T. C. J., Jones, T. H., Stenhagen, G., Loughrin, J. H., & Tumlinson, J. H. (1997) · Science · doi:10.1126/science.276.5314.945 · Cited by 999
Structure of the autoinducer required for expression of Pseudomonas aeruginosa virulence genes.
Pearson, J. P., Gray, K. M., Passador, L., Tucker, K. D., Eberhard, A., Iglewski, B. H., & Greenberg, E. P. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.1.197 · Cited by 990
Structural identification of autoinducer of Photobacterium fischeri luciferase
Eberhard, A., Burlingame, A. L., Eberhard, C., Kenyon, G. L., Nealson, K. H., & Oppenheimer, N. J. (1981) · Biochemistry · doi:10.1021/bi00512a013 · Cited by 986
Quorum sensing in Escherichia coli , Salmonella typhimurium , and Vibrio harveyi : A new family of genes responsible for autoinducer production
Surette, M. G., Miller, M. B., & Bassler, B. L. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.4.1639 · Cited by 976
The Small RNA Chaperone Hfq and Multiple Small RNAs Control Quorum Sensing in Vibrio harveyi and Vibrio cholerae
Lenz, D. H., Mok, K. C., Lilley, B. N., Kulkarni, R. V., Wingreen, N. S., & Bassler, B. L. (2004) · Cell · doi:10.1016/j.cell.2004.06.009 · Cited by 971
The multicellular morphotypes of Salmonella typhimurium and Escherichia coli produce cellulose as the second component of the extracellular matrix
Zogaj, X., Nimtz, M., Rohde, M., Bokranz, W., & Römling, U. (2001) · Molecular Microbiology · doi:10.1046/j.1365-2958.2001.02337.x · Cited by 955
Bacterial bioluminescence: Isolation and genetic analysis of functions from Vibrio fischeri
Engebrecht, J., Nealson, K., & Silverman, M. (1983) · Cell · doi:10.1016/0092-8674(83)90063-6 · Cited by 909
Quorum sensing controls biofilm formation in Vibrio cholerae
Hammer, B. K., & Bassler, B. L. (2003) · Molecular Microbiology · doi:10.1046/j.1365-2958.2003.03688.x · Cited by 886
Expression of Pseudomonas aeruginosa Virulence Genes Requires Cell-to-Cell Communication
Passador, L., Cook, J. M., Gambello, M. J., Rust, L., & Iglewski, B. H. (1993) · Science · doi:10.1126/science.8493556 · Cited by 857
Quorum-sensing regulators control virulence gene expression in Vibrio cholerae
Zhu, J., Miller, M. B., Vance, R. E., Dziejman, M., Bassler, B. L., & Mekalanos, J. J. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.052694299 · Cited by 849
AiiA, an enzyme that inactivates the acylhomoserine lactone quorum-sensing signal and attenuates the virulence of Erwinia carotovora
Dong, Y.-H., Xu, J., Li, X., & Zhang, L. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.7.3526 · Cited by 799
A second N-acylhomoserine lactone signal produced by Pseudomonas aeruginosa.
Pearson, J. P., Passador, L., Iglewski, B. H., & Greenberg, E. P. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.5.1490 · Cited by 784
AiiA, an enzyme that inactivates the acylhomoserine lactone quorum-sensing signal and attenuates the virulence of Erwinia carotovora
Dong, Y.-H. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.060023897 · Cited by 777
Eukaryotic interference with homoserine lactone-mediated prokaryotic signalling
Givskov, M., de Nys, R., Manefield, M., Gram, L., Maximilien, R., Eberl, L., Molin, S., Steinberg, P. D., & Kjelleberg, S. (1996) · Journal of Bacteriology · doi:10.1128/jb.178.22.6618-6622.1996 · Cited by 763
Intercellular signalling in Vibrio harveyi: sequence and function of genes regulating expression of luminescence
Bassler, B. L., Wright, M., Showalter, R. E., & Silverman, M. R. (1993) · Molecular Microbiology · doi:10.1111/j.1365-2958.1993.tb01737.x · Cited by 757
Cross-species induction of luminescence in the quorum-sensing bacterium Vibrio harveyi
Bassler, B. L., Greenberg, E. P., & Stevens, A. M. (1997) · Journal of Bacteriology · doi:10.1128/jb.179.12.4043-4045.1997 · Cited by 755
Detecting and characterizing N -acyl-homoserine lactone signal molecules by thin-layer chromatography
Shaw, P. D., Ping, G., Daly, S. L., Cha, C., Cronan, J. E., Rinehart, K. L., & Farrand, S. K. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.12.6036 · Cited by 748
Genes involved in matrix formation in Pseudomonas aeruginosa PA14 biofilms
Friedman, L., & Kolter, R. (2004) · Molecular Microbiology · doi:10.1046/j.1365-2958.2003.03877.x · Cited by 741
The Relation between Genotype and Phenotype in Cystic Fibrosis — Analysis of the Most Common Mutation (ΔF508)
Kerem, E., Corey, M., Kerem, B.-S., Rommens, J., Markiewicz, D., Levison, H., Tsui, L.-C., & Durie, P. (1990) · New England Journal of Medicine · doi:10.1056/nejm199011293232203 · Cited by 728
Cloning and characterization of the Pseudomonas aeruginosa lasR gene, a transcriptional activator of elastase expression
Gambello, M. J., & Iglewski, B. H. (1991) · Journal of Bacteriology · doi:10.1128/jb.173.9.3000-3009.1991 · Cited by 725
Multiple signalling systems controlling expression of luminescence in Vibrio harveyi: sequence and function of genes encoding a second sensory pathway
Bassler, B. L., Wright, M., & Silverman, M. R. (1994) · Molecular Microbiology · doi:10.1111/j.1365-2958.1994.tb00422.x · Cited by 707
Parallel Quorum Sensing Systems Converge to Regulate Virulence in Vibrio cholerae
Miller, M. B., Skorupski, K., Lenz, D. H., Taylor, R. K., & Bassler, B. L. (2002) · Cell · doi:10.1016/s0092-8674(02)00829-2 · Cited by 648
Production of Acyl-Homoserine Lactone Quorum-Sensing Signals by Gram-Negative Plant-Associated Bacteria
Cha, C., Gao, P., Chen, Y.-C., Shaw, P. D., & Farrand, S. K. (1998) · Molecular Plant-Microbe Interactions® · doi:10.1094/mpmi.1998.11.11.1119 · Cited by 618
N -Acylhomoserine Lactones Undergo Lactonolysis in a pH-, Temperature-, and Acyl Chain Length-Dependent Manner during Growth of Yersinia pseudotuberculosis and Pseudomonas aeruginosa
Yates, E. A., Philipp, B., Buckley, C., Atkinson, S., Chhabra, S. R., Sockett, R. E., Goldner, M., Dessaux, Y., Cámara, M., Smith, H., et al. (2002) · Infection and Immunity · doi:10.1128/iai.70.10.5635-5646.2002 · Cited by 616
The pgaABCD Locus of Escherichia coli Promotes the Synthesis of a Polysaccharide Adhesin Required for Biofilm Formation
Wang, X., Preston, J. F., & Romeo, T. (2004) · Journal of Bacteriology · doi:10.1128/jb.186.9.2724-2734.2004 · Cited by 610
Construction and analysis of luxCDABE-based plasmid sensors for investigating N-acyl homoserine lactone-mediated quorum sensing
Winson, M. (1998) · FEMS Microbiology Letters · doi:10.1016/s0378-1097(98)00172-4 · Cited by 593
Acyl homoserine-lactone quorum-sensing signal generation
Parsek, M. R., Val, D. L., Hanzelka, B. L., Cronan, J. E., & Greenberg, E. P. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.8.4360 · Cited by 592
Vibrio cholerae O1 El Tor: Identification of a gene cluster required for the rugose colony type, exopolysaccharide production, chlorine resistance, and biofilm formation
Yildiz, F. H., & Schoolnik, G. K. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.7.4028 · Cited by 586
Three Parallel Quorum-Sensing Systems Regulate Gene Expression in Vibrio harveyi
Henke, J. M., & Bassler, B. L. (2004) · Journal of Bacteriology · doi:10.1128/jb.186.20.6902-6914.2004 · Cited by 558
Genetic analysis of Salmonella enteritidis biofilm formation: critical role of cellulose
Solano, C., García, B., Valle, J., Berasain, C., Ghigo, J., Gamazo, C., & Lasa, I. (2002) · Molecular Microbiology · doi:10.1046/j.1365-2958.2002.02802.x · Cited by 554
Atomic structure and specificity of bacterial periplasmic receptors for active transport and chemotaxis: variation of common themes
Quiocho, F. A., & Ledvina, P. S. (1996) · Molecular Microbiology · doi:10.1111/j.1365-2958.1996.tb02484.x · Cited by 544
Acyl‐homoserine lactone acylase from Ralstonia strain XJ12B represents a novel and potent class of quorum‐quenching enzymes
Lin, Y., Xu, J., Hu, J., Wang, L., Ong, S. L., Leadbetter, J. R., & Zhang, L. (2003) · Molecular Microbiology · doi:10.1046/j.1365-2958.2003.03351.x · Cited by 544
Long term azithromycin in children with cystic fibrosis: a randomised, placebo-controlled crossover trial
Equi, A., Balfour-Lynn, I., Bush, A., & Rosenthal, M. (2002) · The Lancet · doi:10.1016/s0140-6736(02)11081-6 · Cited by 543
Vibrio biofilms: so much the same yet so different
Yildiz, F. H., & Visick, K. L. (2009) · Trends in Microbiology · doi:10.1016/j.tim.2008.12.004 · Cited by 542
Two Genetic Loci Produce Distinct Carbohydrate-Rich Structural Components of the Pseudomonas aeruginosa Biofilm Matrix
Friedman, L., & Kolter, R. (2004) · Journal of Bacteriology · doi:10.1128/jb.186.14.4457-4465.2004 · Cited by 537
Multiple N-acyl-L-homoserine lactone signal molecules regulate production of virulence determinants and secondary metabolites in Pseudomonas aeruginosa.
Winson, M. K., Camara, M., Latifi, A., Foglino, M., Chhabra, S. R., Daykin, M., Bally, M., Chapon, V, Salmond, G. P., & Bycroft, B. W. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.20.9427 · Cited by 536
Quorum Sensing-Dependent Biofilms Enhance Colonization in Vibrio cholerae
Zhu, J., & Mekalanos, J. J. (2003) · Developmental Cell · doi:10.1016/s1534-5807(03)00295-8 · Cited by 523
β-Oxidation of fatty acids in mitochondria, peroxisomes, and bacteria: A century of continued progress
Kunau, W. (1995) · Progress in Lipid Research · doi:10.1016/0163-7827(95)00011-9 · Cited by 510
Conjugation factor of Agrobacterium tumefaciens regulates Ti plasmid transfer by autoinduction
Piper, K. R., von Bodman, S. B., & Farrand, S. K. (1993) · Nature · doi:10.1038/362448a0 · Cited by 509
Cyclic diguanylate (c‐di‐GMP) regulates Vibrio cholerae biofilm formation
Tischler, A. D., & Camilli, A. (2004) · Molecular Microbiology · doi:10.1111/j.1365-2958.2004.04155.x · Cited by 502
Identification of Quorum-Quenching N -Acyl Homoserine Lactonases from Bacillus Species
Dong, Y.-H., Gusti, A. R., Zhang, Q., Xu, J.-L., & Zhang, L.-H. (2002) · Applied and Environmental Microbiology · doi:10.1128/aem.68.4.1754-1759.2002 · Cited by 497
Expression of the cystic fibrosis gene in non-epithelial invertebrate cells produces a regulated anion conductance
Kartner, N., Hanrahan, J. W., Jensen, T. J., Naismith, A. L., Sun, S., Ackerley, C. A., Reyes, E. F., Tsui, L.-C., Rommens, J. M., Bear, C. E., et al. (1991) · Cell · doi:10.1016/0092-8674(91)90498-n · Cited by 496
A LuxR-LuxI type regulatory system activates Agrobacterium Ti plasmid conjugal transfer in the presence of a plant tumor metabolite
Fuqua, W. C., & Winans, S. C. (1994) · Journal of Bacteriology · doi:10.1128/jb.176.10.2796-2806.1994 · Cited by 495
Metabolism of Acyl-Homoserine Lactone Quorum-Sensing Signals by Variovorax paradoxus
Leadbetter, J. R., & Greenberg, E. P. (2000) · Journal of Bacteriology · doi:10.1128/jb.182.24.6921-6926.2000 · Cited by 491
Indole is an inter-species biofilm signal mediated by SdiA
Lee, J., Jayaraman, A., & Wood, T. K. (2007) · BMC Microbiology · doi:10.1186/1471-2180-7-42 · Cited by 470
Alginate is not a significant component of the extracellular polysaccharide matrix of PA14 and PAO1 Pseudomonas aeruginosa biofilms
Wozniak, D. J., Wyckoff, T. J. O., Starkey, M., Keyser, R., Azadi, P., O'Toole, G. A., & Parsek, M. R. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1231792100 · Cited by 466
The lux autoinducer regulates the production of exoenzyme virulence determinants in Erwinia carotovora and Pseudomonas aeruginosa.
Jones, S., Yu, B., Bainton, N. J., Birdsall, M., Bycroft, B. W., Chhabra, S. R., Cox, A. J., Golby, P., Reeves, P. J., & Stephens, S. (1993) · The EMBO Journal · doi:10.1002/j.1460-2075.1993.tb05902.x · Cited by 459
A small diffusible signal molecule is responsible for the global control of virulence and exoenzyme production in the plant pathogen Erwinia carotovora.
Pirhonen, M., Flego, D., Heikinheimo, R., & Palva, E. T. (1993) · The EMBO Journal · doi:10.1002/j.1460-2075.1993.tb05901.x · Cited by 456
The major Vibrio cholerae autoinducer and its role in virulence factor production
Higgins, D. A., Pomianek, M. E., Kraml, C. M., Taylor, R. K., Semmelhack, M. F., & Bassler, B. L. (2007) · Nature · doi:10.1038/nature06284 · Cited by 455
The cep quorum-sensing system of Burkholderia cepacia H111 controls biofilm formation and swarming motility
Huber, B., Riedel, K., Hentzer, M., Heydorn, A., Gotschlich, A., Givskov, M., Molin, S., & Eberl, L. (2001) · Microbiology · doi:10.1099/00221287-147-9-2517 · Cited by 451
Regulatory cascade controls virulence in Vibrio cholerae.
DiRita, V. J., Parsot, C., Jander, G., & Mekalanos, J. J. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.12.5403 · Cited by 449
Agrobacterium conjugation and gene regulation by N-acyl-L-homoserine lactones
Zhang, L., Murphy, P. J., Kerr, A., & Tate, M. E. (1993) · Nature · doi:10.1038/362446a0 · Cited by 441
Quorum sensing in Pseudomonas aeruginosa biofilms
De Kievit, T. R. (2009) · Environmental Microbiology · doi:10.1111/j.1462-2920.2008.01792.x · Cited by 439
Isolation and characterization of a regulatory gene affecting rhamnolipid biosurfactant synthesis in Pseudomonas aeruginosa
Ochsner, U. A., Koch, A. K., Fiechter, A., & Reiser, J. (1994) · Journal of Bacteriology · doi:10.1128/jb.176.7.2044-2054.1994 · Cited by 429
Production and Characterization of the Slime Polysaccharide of Pseudomonas aeruginosa
Evans, L. R., & Linker, A. (1973) · Journal of Bacteriology · doi:10.1128/jb.116.2.915-924.1973 · Cited by 428
Quorum Sensing Controls Biofilm Formation in Vibrio cholerae through Modulation of Cyclic Di-GMP Levels and Repression of vpsT
Waters, C. M., Lu, W., Rabinowitz, J. D., & Bassler, B. L. (2008) · Journal of Bacteriology · doi:10.1128/jb.01756-07 · Cited by 425
Identification of psl, a Locus Encoding a Potential Exopolysaccharide That Is Essential for Pseudomonas aeruginosa PAO1 Biofilm Formation
Jackson, K. D., Starkey, M., Kremer, S., Parsek, M. R., & Wozniak, D. J. (2004) · Journal of Bacteriology · doi:10.1128/jb.186.14.4466-4475.2004 · Cited by 421
Quorum sensing in Aeromonas hydrophila and Aeromonas salmonicida: identification of the LuxRI homologs AhyRI and AsaRI and their cognate N-acylhomoserine lactone signal molecules
Swift, S., Karlyshev, A. V., Fish, L., Durant, E. L., Winson, M. K., Chhabra, S. R., Williams, P., Macintyre, S., & Stewart, G. S. (1997) · Journal of Bacteriology · doi:10.1128/jb.179.17.5271-5281.1997 · Cited by 415
Enzymatic Synthesis of a Quorum-Sensing Autoinducer Through Use of Defined Substrates
Moré, M. I., Finger, L. D., Stryker, J. L., Fuqua, C., Eberhard, A., & Winans, S. C. (1996) · Science · doi:10.1126/science.272.5268.1655 · Cited by 410
Purification and Structural Identification of an Autoinducer for the Luminescence System of Vibrio harveyi
Cao, J. G., & Meighen, E. A. (1989) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(20)88238-6 · Cited by 401
N-Acylhomoserine-lactone-mediated communication between Pseudomonas aeruginosa and Burkholderia cepacia in mixed biofilms
Riedel, K., Steidle, A., Eberl, L., Wu, H., Geisenberger, O., Molin, S., Huber, B., Hentzer, M., Høiby, N., & Givskov, M. (2001) · Microbiology · doi:10.1099/00221287-147-12-3249 · Cited by 401
Azithromycin Inhibits Quorum Sensing in Pseudomonas aeruginosa
Tateda, K., Comte, R., Péchère, J.-C., et al. (2001) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.45.6.1930-1933.2001 · Cited by 401
Staphylococcus quorum sensing in biofilm formation and infection
Kong, K.-F., Vuong, C., & Otto, M. (2006) · International Journal of Medical Microbiology · doi:10.1016/j.ijmm.2006.01.042 · Cited by 388
Generation of cell-to-cell signals in quorum sensing: acyl homoserine lactone synthase activity of a purified Vibrio fischeri LuxI protein.
Schaefer, A. L., Val, D. L., Hanzelka, B. L., Cronan, J. E., & Greenberg, E. P. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.18.9505 · Cited by 380
Detection of quorum-sensing N-acyl homoserine lactone signal molecules by bacterial biosensors
Steindler, L., & Venturi, V. (2007) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.2006.00501.x · Cited by 378
Burkholderia phytofirmans sp. nov., a novel plant-associated bacterium with plant-beneficial properties.
Sessitsch, A., Coenye, T., Sturz, A. V., Vandamme, P., Barka, E. A., Salles, J. F., Van Elsas, J. D., Faure, D., Reiter, B., Glick, B. R., et al. (2005) · International Journal of Systematic and Evolutionary Microbiology · doi:10.1099/ijs.0.63149-0 · Cited by 375
A genetic analysis of the function of LuxO, a two‐component response regulator involved in quorum sensing in Vibrio harveyi
Freeman, J. A., & Bassler, B. L. (1999) · Molecular Microbiology · doi:10.1046/j.1365-2958.1999.01208.x · Cited by 360
Quorum Sensing in Burkholderia cepacia : Identification of the LuxRI Homologs CepRI
Lewenza, S., Conway, B., Greenberg, E. P., & Sokol, P. A. (1999) · Journal of Bacteriology · doi:10.1128/jb.181.3.748-756.1999 · Cited by 355
Involvement of N-acyl-l-homoserine lactone autoinducers in controlling the multicellular behaviour of Serratia liquefaciens
Eberl, L., Winson, M. K., Sternberg, C., Stewart, G. S. A. B., Christiansen, G., Chhabra, S. R., Bycroft, B., Williams, P., Molin, S., & Givskov, M. (1996) · Molecular Microbiology · doi:10.1111/j.1365-2958.1996.tb02495.x · Cited by 350
A scanning and transmission electron microscopic study of an infected endocardial pacemaker lead.
Marrie, T. J., Nelligan, J., & Costerton, J. W. (1982) · Circulation · doi:10.1161/01.cir.66.6.1339 · Cited by 347
Utilization of Acyl-Homoserine Lactone Quorum Signals for Growth by a Soil Pseudomonad and Pseudomonas aeruginosa PAO1
Huang, J. J., Han, J.-I., Zhang, L.-H., & Leadbetter, J. R. (2003) · Applied and Environmental Microbiology · doi:10.1128/aem.69.10.5941-5949.2003 · Cited by 347
c-di-GMP-mediated regulation of virulence and biofilm formation
Cotter, P. A., & Stibitz, S. (2007) · Current Opinion in Microbiology · doi:10.1016/j.mib.2006.12.006 · Cited by 344
Activation of the Pseudomonas aeruginosa lasI gene by LasR and the Pseudomonas autoinducer PAI: an autoinduction regulatory hierarchy
Seed, P. C., Passador, L., & Iglewski, B. H. (1995) · Journal of Bacteriology · doi:10.1128/jb.177.3.654-659.1995 · Cited by 343
Genetic control of quorum-sensing signal turnover in Agrobacterium tumefaciens
Zhang, H.-B., Wang, L.-H., & Zhang, L.-H. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.022056699 · Cited by 342
gfp -Based N -Acyl Homoserine-Lactone Sensor Systems for Detection of Bacterial Communication
Andersen, J. B., Heydorn, A., Hentzer, M., Eberl, L., Geisenberger, O., Christensen, B. B., Molin, S., & Givskov, M. (2001) · Applied and Environmental Microbiology · doi:10.1128/aem.67.2.575-585.2001 · Cited by 339
Putative Exopolysaccharide Synthesis Genes Influence Pseudomonas aeruginosa Biofilm Development
Matsukawa, M., & Greenberg, E. P. (2004) · Journal of Bacteriology · doi:10.1128/jb.186.14.4449-4456.2004 · Cited by 336
Quorum Sensing Regulates Type III Secretion in Vibrio harveyi and Vibrio parahaemolyticus
Henke, J. M., & Bassler, B. L. (2004) · Journal of Bacteriology · doi:10.1128/jb.186.12.3794-3805.2004 · Cited by 332
The regulation of biofilm development by quorum sensing in Aeromonas hydrophila
Lynch, M. J., Swift, S., Kirke, D. F., Keevil, C. W., Dodd, C. E. R., & Williams, P. (2002) · Environmental Microbiology · doi:10.1046/j.1462-2920.2002.00264.x · Cited by 327
Inhibition of biofilm formation and swarming of Escherichia coli by ( 5Z )‐4‐bromo‐5‐(bromomethylene)‐3‐butyl‐2( 5H )‐furanone
Ren, D., Sims, J. J., & Wood, T. K. (2001) · Environmental Microbiology · doi:10.1046/j.1462-2920.2001.00249.x · Cited by 327
A novel and sensitive method for the quantification of N ‐3‐oxoacyl homoserine lactones using gas chromatography–mass spectrometry: application to a model bacterial biofilm
Charlton, T. S., De Nys, R., Netting, A., Kumar, N., Hentzer, M., Givskov, M., & Kjelleberg, S. (2000) · Environmental Microbiology · doi:10.1046/j.1462-2920.2000.00136.x · Cited by 322
Quorum Quenching by an N -Acyl-Homoserine Lactone Acylase from Pseudomonas aeruginosa PAO1
Sio, C. F., Otten, L. G., Cool, R. H., Diggle, S. P., Braun, P. G., Bos, R., Daykin, M., Cámara, M., Williams, P., & Quax, W. J. (2006) · Infection and Immunity · doi:10.1128/iai.74.3.1673-1682.2006 · Cited by 322
Regulation of quorum sensing in Vibrio harveyi by LuxO and Sigma‐54
Lilley, B. N., & Bassler, B. L. (2000) · Molecular Microbiology · doi:10.1046/j.1365-2958.2000.01913.x · Cited by 318
Quorum Sensing Regulates Exopolysaccharide Production, Motility, and Virulence in Pseudomonas syringae
Quiñones, B., Dulla, G., & Lindow, S. E. (2005) · Molecular Plant-Microbe Interactions® · doi:10.1094/mpmi-18-0682 · Cited by 301
Biosynthesis of carbapenem antibiotic and prodigiosin pigment in Serratia is under quorum sensing control
Thomson, N. R., Crow, M. A., McGowan, S. J., Cox, A., & Salmond, G. P. C. (2000) · Molecular Microbiology · doi:10.1046/j.1365-2958.2000.01872.x · Cited by 298
The EAL Domain Protein VieA Is a Cyclic Diguanylate Phosphodiesterase
Tamayo, R., Tischler, A. D., & Camilli, A. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m506500200 · Cited by 291
Capsular polysaccharide biosynthesis and pathogenicity in Erwinia stewartii require induction by an N-acylhomoserine lactone autoinducer
Beck von Bodman, S., & Farrand, S. K. (1995) · Journal of Bacteriology · doi:10.1128/jb.177.17.5000-5008.1995 · Cited by 286
Evidence of autoinducer activity in naturally occurring biofilms
McLean, R. J. C., Whiteley, M., Stickler, D. J., & Fuqua, W. C. (2006) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.1997.tb12653.x · Cited by 284
Biofilm Formation and Sloughing in Serratia marcescens Are Controlled by Quorum Sensing and Nutrient Cues
Rice, S. A., Koh, K. S., Queck, S. Y., Labbate, M., Lam, K. W., & Kjelleberg, S. (2005) · Journal of Bacteriology · doi:10.1128/jb.187.10.3477-3485.2005 · Cited by 282
Isolation and Characterization of an Autoinducer Synthase from Acinetobacter baumannii
Niu, C., Clemmer, K. M., Bonomo, R. A., & Rather, P. N. (2008) · Journal of Bacteriology · doi:10.1128/jb.01929-07 · Cited by 279
N-Acylhomoserine lactone quorum-sensing molecules are modified and degraded by Rhodococcus erythropolis W2 by both amidolytic and novel oxidoreductase activities
Uroz, S., Chhabra, S. R., Cámara, M., Williams, P. M., Oger, P., & Dessaux, Y. (2005) · Microbiology · doi:10.1099/mic.0.27961-0 · Cited by 278
N-(3-oxohexanoyl)-l-homoserine lactone regulates carbapenem antibiotic production in Erwinia carotovora
Bainton, N. J., Stead, P., Chhabra, S. R., Bycroft, B. W., Salmond, G. P. C., Stewart, G. S. A. B., & Williams, P. (1992) · Biochemical Journal · doi:10.1042/bj2880997 · Cited by 276
Long-term azithromycin may improve lung function in children with cystic fibrosis
Jaffé, A., Francis, J., Rosenthal, M., & Bush, A. (1998) · The Lancet · doi:10.1016/s0140-6736(05)78360-4 · Cited by 276
Structural Basis and Specificity of Acyl-Homoserine Lactone Signal Production in Bacterial Quorum Sensing
Watson, W. T., Minogue, T. D., Val, D. L., von Bodman, S. B., & Churchill, M. E. A. (2002) · Molecular Cell · doi:10.1016/s1097-2765(02)00480-x · Cited by 274
Visualization of N -Acylhomoserine Lactone-Mediated Cell-Cell Communication between Bacteria Colonizing the Tomato Rhizosphere
Steidle, A., Sigl, K., Schuhegger, R., Ihring, A., Schmid, M., Gantner, S., Stoffels, M., Riedel, K., Givskov, M., Hartmann, A., et al. (2001) · Applied and Environmental Microbiology · doi:10.1128/aem.67.12.5761-5770.2001 · Cited by 268
A negative regulator mediates quorum-sensing control of exopolysaccharide production in Pantoea stewartii subsp. stewartii
von Bodman, S. B., Majerczak, D. R., & Coplin, D. L. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.13.7687 · Cited by 263
AhlD, an N-acylhomoserine lactonase in Arthrobacter sp., and predicted homologues in other bacteria
Park, S.-Y., Lee, S. J., Oh, T.-K., Oh, J.-W., Koo, B.-T., Yum, D.-Y., & Lee, J.-K. (2003) · Microbiology · doi:10.1099/mic.0.26269-0 · Cited by 262
Quorum-sensing regulation governs bacterial adhesion, biofilm development, and host colonization in Pantoea stewartii subspecies stewartii
Koutsoudis, M. D., Tsaltas, D., Minogue, T. D., & von Bodman, S. B. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0509860103 · Cited by 260
Cyclic Diguanylate Regulates Vibrio cholerae Virulence Gene Expression
Tischler, A. D., & Camilli, A. (2005) · Infection and Immunity · doi:10.1128/iai.73.9.5873-5882.2005 · Cited by 258
Genetically programmed autoinducer destruction reduces virulence gene expression and swarming motility in Pseudomonas aeruginosa PAO1 The GenBank accession number for the aiiA nucleotide sequence is AF397400. The GenBank accession numbers for the nucleotide sequences of the 16S rRNA genes of strains A23 and A24 are AF397398 and AF397399.
Reimmann, C., Ginet, N., Michel, L., Keel, C., Michaux, P., Krishnapillai, V., Zala, M., Heurlier, K., Triandafillu, K., Harms, H., et al. (2002) · Microbiology · doi:10.1099/00221287-148-4-923 · Cited by 257
Characterization of hapR, a positive regulator of the Vibrio cholerae HA/protease gene hap, and its identification as a functional homologue of the Vibrio harveyi luxR gene
Jobling, M. G., & Holmes, R. K. (1997) · Molecular Microbiology · doi:10.1046/j.1365-2958.1997.6402011.x · Cited by 256
N-Acylhomoserine lactone regulates violacein production in Chromobacterium violaceum type strain ATCC 12472
Morohoshi, T., Kato, M., Fukamachi, K., Kato, N., & Ikeda, T. (2008) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.2007.01016.x · Cited by 255
Sequence and Function of LuxU: a Two-Component Phosphorelay Protein That Regulates Quorum Sensing in Vibrio harveyi
Freeman, J. A., & Bassler, B. L. (1999) · Journal of Bacteriology · doi:10.1128/jb.181.3.899-906.1999 · Cited by 251
Quorum sensing and the LysR‐type transcriptional activator ToxR regulate toxoflavin biosynthesis and transport in Burkholderia glumae
Kim, J., Kim, J., Kang, Y., Jang, J. Y., Jog, G. J., Lim, J. Y., Kim, S., Suga, H., Nagamatsu, T., & Hwang, I. (2004) · Molecular Microbiology · doi:10.1111/j.1365-2958.2004.04338.x · Cited by 242
Characterization of the Sinorhizobium meliloti sinR/sinI Locus and the Production of Novel N-Acyl Homoserine Lactones
Marketon, M. M., Gronquist, M. R., Eberhard, A., & González, J. E. (2002) · Journal of Bacteriology · doi:10.1128/jb.184.20.5686-5695.2002 · Cited by 240
Novel bacteria degrading N-acylhomoserine lactones and their use as quenchers of quorum-sensing-regulated functions of plant-pathogenic bacteria
Uroz, S., D'Angelo-Picard, C., Carlier, A., Elasri, M., Sicot, C., Petit, A., Oger, P., Faure, D., & Dessaux, Y. (2003) · Microbiology · doi:10.1099/mic.0.26375-0 · Cited by 234
Regulation of virulence gene expression in Vibrio cholerae by quorum sensing: HapR functions at the aphA promoter
Kovacikova, G., & Skorupski, K. (2002) · Molecular Microbiology · doi:10.1046/j.1365-2958.2002.03229.x · Cited by 230
VpsR, a Member of the Response Regulators of the Two-Component Regulatory Systems, Is Required for Expression of vps Biosynthesis Genes and EPS ETr -Associated Phenotypes in Vibrio cholerae O1 El Tor
Yildiz, F. H., Dolganov, N. A., & Schoolnik, G. K. (2001) · Journal of Bacteriology · doi:10.1128/jb.183.5.1716-1726.2001 · Cited by 229
Inhibition of Luminescence and Virulence in the Black Tiger Prawn ( Penaeus monodon ) Pathogen Vibrio harveyi by Intercellular Signal Antagonists
Manefield, M., Harris, L., Rice, S. A., de Nys, R., & Kjelleberg, S. (2000) · Applied and Environmental Microbiology · doi:10.1128/aem.66.5.2079-2084.2000 · Cited by 225
A quorum-sensing system in the free-living photosynthetic bacterium Rhodobacter sphaeroides
Puskas, A., Greenberg, E. P., Kaplan, S., & Schaefer, A. L. (1997) · Journal of Bacteriology · doi:10.1128/jb.179.23.7530-7537.1997 · Cited by 221
TraI, a LuxI homologue, is responsible for production of conjugation factor, the Ti plasmid N-acylhomoserine lactone autoinducer.
Hwang, I., Li, P. L., Zhang, L., Piper, K. R., Cook, D. M., Tate, M. E., & Farrand, S. K. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.11.4639 · Cited by 220
Differential gene expression shows natural brominated furanones interfere with the autoinducer‐2 bacterial signaling system of Escherichia coli
Ren, D., Bedzyk, L. A., Ye, R. W., Thomas, S. M., & Wood, T. K. (2004) · Biotechnology and Bioengineering · doi:10.1002/bit.20259 · Cited by 219
Quorum Sensing Controls Exopolysaccharide Production in Sinorhizobium meliloti
Marketon, M. M., Glenn, S. A., Eberhard, A., & González, J. E. (2002) · Journal of Bacteriology · doi:10.1128/jb.185.1.325-331.2003 · Cited by 212
N-acyl-homoserine lactone-mediated regulation of phenazine gene expression by Pseudomonas aureofaciens 30-84 in the wheat rhizosphere
Wood, D. W., Gong, F., Daykin, M. M., Williams, P., & Pierson, L. S. (1997) · Journal of Bacteriology · doi:10.1128/jb.179.24.7663-7670.1997 · Cited by 211
The biocontrol strain Pseudomonas fluorescens F113 produces the Rhizobium small bacteriocin, N-(3-hydroxy-7-cis-tetradecenoyl)homoserine lactone, via HdtS, a putative novel N-acylhomoserine lactone synthase The GenBank accession number for the sequence determined in this work is AF286536.
Laue, B. E., Jiang, Y., Chhabra, S. R., Jacob, S., Stewart, G. S. A. B., Hardman, A., Downie, J. A., O’Gara, F., & Williams, P. M. (2000) · Microbiology · doi:10.1099/00221287-146-10-2469 · Cited by 211
The Ti Plasmid of Agrobacterium tumefaciens Harbors an attM -Paralogous Gene, aiiB , Also Encoding N -Acyl Homoserine Lactonase Activity
Carlier, A. L., Uroz, S., Smadja, B., Fray, R. G., Latour, X., Dessaux, Y., & Faure, D. (2003) · Applied and Environmental Microbiology · doi:10.1128/aem.69.8.4989-4993.2003 · Cited by 204
Biofilm formation by Pseudomonas aeruginosa: role of the C4-HSL cell-to-cell signal and inhibition by azithromycin
Favre-Bonte, S. (2003) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkg397 · Cited by 201
Structure of the Pseudomonas aeruginosa acyl‐homoserinelactone synthase LasI
Gould, T. A., Schweizer, H. P., & Churchill, M. E. A. (2004) · Molecular Microbiology · doi:10.1111/j.1365-2958.2004.04211.x · Cited by 200
Identification of the operator of the lux regulon from the Vibrio fischeri strain ATCC7744.
Devine, J. H., Shadel, G. S., & Baldwin, T. O. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.15.5688 · Cited by 200
Discovery of Complex Mixtures of Novel Long‐Chain Quorum Sensing Signals in Free‐Living and Host‐Associated Marine Alphaproteobacteria
Wagner‐Döbler, I., Thiel, V., Eberl, L., Allgaier, M., Bodor, A., Meyer, S., Ebner, S., Hennig, A., Pukall, R., & Schulz, S. (2005) · ChemBioChem · doi:10.1002/cbic.200500189 · Cited by 197
Enterohemorrhagic Escherichia coli Biofilms Are Inhibited by 7-Hydroxyindole and Stimulated by Isatin
Lee, J., Bansal, T., Jayaraman, A., Bentley, W. E., & Wood, T. K. (2007) · Applied and Environmental Microbiology · doi:10.1128/aem.00360-07 · Cited by 197
Down Regulation of Virulence Factors of Pseudomonas aeruginosa by Salicylic Acid Attenuates Its Virulence on Arabidopsis thaliana and Caenorhabditis elegans
Prithiviraj, B., Bais, H. P., Weir, T., Suresh, B., Najarro, E. H., Dayakar, B. V., Schweizer, H. P., & Vivanco, J. M. (2005) · Infection and Immunity · doi:10.1128/iai.73.9.5319-5328.2005 · Cited by 195
A Vibrio cholerae LysR Homolog, AphB, Cooperates with AphA at the tcpPH Promoter To Activate Expression of the ToxR Virulence Cascade
Kovacikova, G., & Skorupski, K. (1999) · Journal of Bacteriology · doi:10.1128/jb.181.14.4250-4256.1999 · Cited by 192
VpsT Is a Transcriptional Regulator Required for Expression of vps Biosynthesis Genes and the Development of Rugose Colonial Morphology in Vibrio cholerae O1 El Tor
Casper-Lindley, C., & Yildiz, F. H. (2004) · Journal of Bacteriology · doi:10.1128/jb.186.5.1574-1578.2004 · Cited by 192
Controlling Bacterial Biofilms
Richards, J. J., & Melander, C. (2009) · ChemBioChem · doi:10.1002/cbic.200900317 · Cited by 189
Cyclic‐diGMP signal transduction systems in Vibrio cholerae: modulation of rugosity and biofilm formation
Lim, B., Beyhan, S., Meir, J., & Yildiz, F. H. (2006) · Molecular Microbiology · doi:10.1111/j.1365-2958.2006.05106.x · Cited by 189
Enzymic synthesis of monounsaturated fatty acids
Bloch, K. (1969) · Accounts of Chemical Research · doi:10.1021/ar50019a001 · Cited by 188
Quorum Sensing-Disrupting Brominated Furanones Protect the Gnotobiotic Brine Shrimp Artemia franciscana from Pathogenic Vibrio harveyi , Vibrio campbellii , and Vibrio parahaemolyticus Isolates
Defoirdt, T., Crab, R., Wood, T. K., Sorgeloos, P., Verstraete, W., & Bossier, P. (2006) · Applied and Environmental Microbiology · doi:10.1128/aem.00753-06 · Cited by 186
Vibrio cholerae: Cholera toxin
Vanden Broeck, D., Horvath, C., & De Wolf, M. J. S. (2007) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2007.07.005 · Cited by 179
Identification of QuiP, the Product of Gene PA1032, as the Second Acyl-Homoserine Lactone Acylase of Pseudomonas aeruginosa PAO1
Huang, J. J., Petersen, A., Whiteley, M., & Leadbetter, J. R. (2006) · Applied and Environmental Microbiology · doi:10.1128/aem.72.2.1190-1197.2006 · Cited by 177
Quorum sensing in Vibrio anguillarum: characterization of the vanI/vanR locus and identification of the autoinducer N-(3-oxodecanoyl)-L-homoserine lactone
Milton, D. L., Hardman, A., Camara, M., Chhabra, S. R., Bycroft, B. W., Stewart, G. S., & Williams, P. (1997) · Journal of Bacteriology · doi:10.1128/jb.179.9.3004-3012.1997 · Cited by 176
Multiple N-acyl-L-homoserine lactone autoinducers of luminescence in the marine symbiotic bacterium Vibrio fischeri
Kuo, A., Blough, N. V., & Dunlap, P. V. (1994) · Journal of Bacteriology · doi:10.1128/jb.176.24.7558-7565.1994 · Cited by 175
On-line high-performance liquid chromatography–mass spectrometric detection and quantification of N-acylhomoserine lactones, quorum sensing signal molecules, in the presence of biological matrices
Morin, D., Grasland, B., Vallée-Réhel, K., Dufau, C., & Haras, D. (2003) · Journal of Chromatography A · doi:10.1016/s0021-9673(03)00730-1 · Cited by 174
Halogenated furanones from the red alga, Delisea pulchra, inhibit carbapenem antibiotic synthesis and exoenzyme virulence factor production in the phytopathogen Erwinia carotovora
Manefield, M. (2001) · FEMS Microbiology Letters · doi:10.1016/s0378-1097(01)00460-8 · Cited by 172
Quorum sensing in Cyanobacteria: N-octanoyl-homoserine lactone release and response, by the epilithic colonial cyanobacterium Gloeothece PCC6909
Sharif, D. I., Gallon, J., Smith, C. J., & Dudley, E. (2008) · The ISME Journal · doi:10.1038/ismej.2008.68 · Cited by 172
Poly-N-acetylglucosamine mediates biofilm formation and antibiotic resistance in Actinobacillus pleuropneumoniae
Izano, E. A., Sadovskaya, I., Vinogradov, E., Mulks, M. H., Velliyagounder, K., Ragunath, C., Kher, W. B., Ramasubbu, N., Jabbouri, S., Perry, M. B., et al. (2007) · Microbial Pathogenesis · doi:10.1016/j.micpath.2007.02.004 · Cited by 170
Sequence and function of LuxO, a negative regulator of luminescence in Vibrio harveyi
Bassler, B. L., Wright, M., & Silverman, M. R. (1994) · Molecular Microbiology · doi:10.1111/j.1365-2958.1994.tb01029.x · Cited by 170
Bacteriocin small of Rhizobium leguminosarum belongs to the class of N-acyl-L-homoserine lactone molecules, known as autoinducers and as quorum sensing co-transcription factors
Schripsema, J., de Rudder, K. E., van Vliet, T. B., Lankhorst, P. P., de Vroom, E., Kijne, J. W., & van Brussel, A. A. (1996) · Journal of Bacteriology · doi:10.1128/jb.178.2.366-371.1996 · Cited by 167
The LuxR family protein SpnR functions as a negative regulator of N‐acylhomoserine lactone‐dependent quorum sensing in Serratia marcescens
Horng, Y., Deng, S., Daykin, M., Soo, P., Wei, J., Luh, K., Ho, S., Swift, S., Lai, H., & Williams, P. (2002) · Molecular Microbiology · doi:10.1046/j.1365-2958.2002.03117.x · Cited by 164
Cell-to-cell signaling in the symbiotic nitrogen-fixing bacterium Rhizobium leguminosarum: autoinduction of a stationary phase and rhizosphere-expressed genes
Gray, K. M., Pearson, J. P., Downie, J. A., Boboye, B. E., & Greenberg, E. P. (1996) · Journal of Bacteriology · doi:10.1128/jb.178.2.372-376.1996 · Cited by 163
Synthesis of Multiple N-Acylhomoserine Lactones is Wide-spread Among the Members of the Burkholderia cepacia Complex
Gotschlich, A., Huber, B., Geisenberger, O., Tögl, A., Steidle, A., Riedel, K., Hill, P., Tümmler, B., Vandamme, P., Middleton, B., et al. (2001) · Systematic and Applied Microbiology · doi:10.1078/0723-2020-00013 · Cited by 161
Antimicrobial activity of diterpenoids from hairy roots of Salvia sclarea L.: Salvipisone as a potential anti-biofilm agent active against antibiotic resistant Staphylococci
Kuźma, Ł., Różalski, M., Walencka, E., Różalska, B., & Wysokińska, H. (2007) · Phytomedicine · doi:10.1016/j.phymed.2005.10.008 · Cited by 160
Nucleotide sequence of the regulatory locus controlling expression of bacterial genes for bioluminescence
Engebrecht, J., & Silverman, M. R. (1987) · Nucleic Acids Research · doi:10.1093/nar/15.24.10455 · Cited by 156
Characterisation of the yenI/yenR locus from Yersinia enterocolitica mediating the synthesis of two N‐acylhomoserine lactone signal molecules
Throup, J. P., Cámara, M., Briggs, G. S., et al. (1995) · Molecular Microbiology · doi:10.1111/j.1365-2958.1995.mmi_17020345.x · Cited by 156
The Influence of Azithromycin on the Biofilm Formation of Pseudomonas aeruginosa in vitro
Ichimiya, T., Takeoka, K., Hiramatsu, K., Hirai, K., Yamasaki, T., & Nasu, M. (2009) · Chemotherapy · doi:10.1159/000239440 · Cited by 156
New fatty acid amides from regurgitant of Lepidopteran (Noctuidae, Geometridae) caterpillars
Pohnert, G., Jung, V., Haukioja, E., Lempa, K., & Boland, W. (1999) · Tetrahedron · doi:10.1016/s0040-4020(99)00639-0 · Cited by 152
Quorum sensing in Vibrio fischeri: evidence that S-adenosylmethionine is the amino acid substrate for autoinducer synthesis
Hanzelka, B. L., & Greenberg, E. P. (1996) · Journal of Bacteriology · doi:10.1128/jb.178.17.5291-5294.1996 · Cited by 151
Identification and Characterization of an N -Acylhomoserine Lactone-Dependent Quorum-Sensing System in Pseudomonas putida Strain IsoF
Steidle, A., Allesen‐Holm, M., Riedel, K., Berg, G., Givskov, M., Molin, S., & Eberl, L. (2002) · Applied and Environmental Microbiology · doi:10.1128/aem.68.12.6371-6382.2002 · Cited by 150
Quorum Sensing inYersinia enterocoliticaControls Swimming and Swarming Motility
Atkinson, S., Chang, C., Sockett, R. E., Cámara, M., & Williams, P. M. (2006) · Journal of Bacteriology · doi:10.1128/jb.188.4.1451-1461.2006 · Cited by 149
Quorum quenching activity in Anabaena sp. PCC 7120: identification of AiiC, a novel AHL-acylase
Romero, M., Diggle, S. P., Heeb, S., Cámara, M., & Otero, A. (2008) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.2007.01046.x · Cited by 147
Phenazine-1-Carboxamide Production in the Biocontrol Strain Pseudomonas chlororaphis PCL1391 Is Regulated by Multiple Factors Secreted into the Growth Medium
Chin‐A‐Woeng, T. F. C., van den Broek, D. A., de Voer, G., van der Drift, K. M. G. M., Tuinman, S., THOMAS‐OATES, J. E., Lugtenberg, B. J. J., & Bloemberg, G. V. (2001) · Molecular Plant-Microbe Interactions · doi:10.1094/mpmi.2001.14.8.969 · Cited by 145
Long-Chain Acyl-Homoserine Lactone Quorum-Sensing Regulation of Rhodobacter capsulatus Gene Transfer Agent Production
Schaefer, A. L., Taylor, T. A., Beatty, J. T., & Greenberg, E. P. (2002) · Journal of Bacteriology · doi:10.1128/jb.184.23.6515-6521.2002 · Cited by 143
Evidence for a Functional Quorum-Sensing Type AI-1 System in the Extremophilic Bacterium Acidithiobacillus ferrooxidans
Farah, C. R. T., Vera, M. A., Morin, D., Haras, D., Jerez, C. A., & Guiliani, N. (2005) · Applied and Environmental Microbiology · doi:10.1128/aem.71.11.7033-7040.2005 · Cited by 141
In Vivo Evidence that S -Adenosylmethionine and Fatty Acid Synthesis Intermediates Are the Substrates for the LuxI Family of Autoinducer Synthases
Val, D. L., & Cronan, J. E. (1998) · Journal of Bacteriology · doi:10.1128/jb.180.10.2644-2651.1998 · Cited by 140
l -Canavanine Made byMedicago sativaInterferes with Quorum Sensing inSinorhizobium meliloti
Keshavan, N. D., Chowdhary, P. K., Haines, D. C., & González, J. E. (2005) · Journal of Bacteriology · doi:10.1128/jb.187.24.8427-8436.2005 · Cited by 138
Quorum-sensing-directed protein expression in Serratia proteamaculans B5a
Christensen, A. B., Riedel, K., Eberl, L., Flodgaard, L. R., Molin, S., Gram, L., & Givskov, M. (2003) · Microbiology · doi:10.1099/mic.0.25575-0 · Cited by 137
Dual regulation of genes involved in acetoin biosynthesis and motility/biofilm formation by the virulence activator AphA and the acetate‐responsive LysR‐type regulator AlsR in Vibrio cholerae
Kovacikova, G., Lin, W., & Skorupski, K. (2005) · Molecular Microbiology · doi:10.1111/j.1365-2958.2005.04700.x · Cited by 133
Regulation of polar flagellum genes is mediated by quorum sensing and FlhDC in Burkholderia glumae
Kim, J., Kang, Y., Choi, O., Jeong, Y., Jeong, J., Lim, J. Y., Kim, M., Moon, J. S., Suga, H., & Hwang, I. (2007) · Molecular Microbiology · doi:10.1111/j.1365-2958.2007.05646.x · Cited by 128
Role of quorum sensing in the pathogenicity of Burkholderia pseudomallei
Ulrich, R. L., DeShazer, D., Brueggemann, E. E., Hines, H. B., Oyston, P. C. F., & Jeddeloh, J. A. (2004) · Journal of Medical Microbiology · doi:10.1099/jmm.0.45661-0 · Cited by 125
Comprehensive profiling of N-acylhomoserine lactones produced by Yersinia pseudotuberculosis using liquid chromatography coupled to hybrid quadrupole–linear ion trap mass spectrometry
Ortori, C. A., Atkinson, S., Chhabra, S. R., Cámara, M., Williams, P. M., & Barrett, D. A. (2006) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-006-0710-0 · Cited by 124
Three-dimensional structure of the quorum-quenching N -acyl homoserine lactone hydrolase from Bacillus thuringiensis
Liu, D., Lepore, B. W., Petsko, G. A., Thomas, P. W., Stone, E. M., Fast, W. L., & Ringe, D. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0505255102 · Cited by 124
Identification of Acyl-Homoserine Lactone Signal Molecules Produced by Nitrosomonas europaea Strain Schmidt
Burton, E. O., Read, H. W., Pellitteri-Hahn, M. C., & Hickey, W. J. (2005) · Applied and Environmental Microbiology · doi:10.1128/aem.71.8.4906-4909.2005 · Cited by 124
The molecular structure and catalytic mechanism of a quorum-quenching N-acyl-L-homoserine lactone hydrolase
Kim, M. H., Choi, W., Kang, H. O., et al. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0504996102 · Cited by 123
Quorum sensing signal molecules (acylated homoserine lactones) in Gram-negative fish pathogenic bacteria
Bruhn, J., Dalsgaard, I., Nielsen, K. F., Buchholtz, C., Larsen, J., & Gram, L. (2005) · Diseases of Aquatic Organisms · doi:10.3354/dao065043 · Cited by 122
Quorum-sensing signaling is required for production of the antibiotic pyrrolnitrin in a rhizospheric biocontrol strain ofSerratia plymuthica
Liu, X., Bimerew, M., Ma, Y., MÃ¼ller, H., Ovadis, M. I., Eberl, L., Berg, G., & Chernin, L. S. (2007) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.2007.00681.x · Cited by 118
Secondary Metabolites of Flustra foliace a and Their Influence on Bacteria
Peters, L., König, G. M., Wright, A. D., Pukall, R., Stackebrandt, E. S., Eberl, L., & Riedel, K. (2003) · Applied and Environmental Microbiology · doi:10.1128/aem.69.6.3469-3475.2003 · Cited by 118
Biofilm Formation and Acyl Homoserine Lactone Production in the Burkholderia cepacia Complex
Conway, B. D., Venu, V., & Speert, D. P. (2002) · Journal of Bacteriology · doi:10.1128/jb.184.20.5678-5685.2002 · Cited by 115
Characterization of a Phenazine-Producing Strain Pseudomonas chlororaphis GP72 with Broad-Spectrum Antifungal Activity from Green Pepper Rhizosphere
Liu, H.-M., He, Y.-J., Jiang, H., Peng, H., Huang, X., Zhang, X., Thomashow, L. S., & Xu, Y. (2007) · Current Microbiology · doi:10.1007/s00284-006-0444-4 · Cited by 114
Influence of fusaric acid on phenazine-1-carboxamide synthesis and gene expression of Pseudomonas chlororaphis strain PCL1391
van Rij, T., Girard, G., Lugtenberg, B. J. J., & Bloemberg, G. V. (2005) · Microbiology · doi:10.1099/mic.0.28063-0 · Cited by 108
TheppuI-rsaL-ppuRQuorum-Sensing System Regulates Biofilm Formation ofPseudomonas putidaPCL1445 by Controlling Biosynthesis of the Cyclic Lipopeptides Putisolvins I and II
Dubern, J., Lugtenberg, B. J. J., & Bloemberg, G. V. (2006) · Journal of Bacteriology · doi:10.1128/jb.188.8.2898-2906.2006 · Cited by 107
Isolation, structural characterization, and immunological evaluation of a high-molecular-weight exopolysaccharide from Staphylococcus aureus
Joyce, J. G., Abeygunawardana, C., Xu, Q., Cook, J. C., Hepler, R. W., Przysiecki, C. T., Grimm, K. M., Roper, K., Ip, C. C. Y., Cope, L. D., et al. (2003) · Carbohydrate Research · doi:10.1016/s0008-6215(03)00045-4 · Cited by 106
Endophytic root colonization of gramineous plants by Herbaspirillum frisingense
Rothballer, M., Eckert, B., Schmid, M., Fekete, Á., Schloter, M., Lehner, A., Pollmann, S., & Hartmann, A. (2008) · FEMS Microbiology Ecology · doi:10.1111/j.1574-6941.2008.00582.x · Cited by 103
Identification of a Quorum-Sensing Signal Molecule in the Facultative Intracellular PathogenBrucella melitensis
Taminiau, B., Daykin, M., Swift, S., Boschiroli, M.-L., Tibor, A., Lestrate, P., Bolle, X. D., O’Callaghan, D., Williams, P. M., & Letesson, J. (2002) · Infection and Immunity · doi:10.1128/iai.70.6.3004-3011.2002 · Cited by 96
Involvement of Bacterial Quorum-Sensing Signals in Spoilage of Bean Sprouts
Rasch, M., Andersen, J. B., Nielsen, K. F., et al. (2005) · Applied and Environmental Microbiology · doi:10.1128/aem.71.6.3321-3330.2005 · Cited by 95
Production of Acylated Homoserine Lactones by Psychrotrophic Members of the Enterobacteriaceae Isolated from Foods
Gram, L., Christensen, A. B., Flodgaard, L. R., Molin, S., & Givskov, M. (1999) · Applied and Environmental Microbiology · doi:10.1128/aem.65.8.3458-3463.1999 · Cited by 94
Involvement of two A‐factor receptor homologues in Streptomyces coelicolor A3(2) in the regulation of secondary metabolism and morphogenesis
Onaka, H., Nakagawa, T., & Horinouchi, S. (1998) · Molecular Microbiology · doi:10.1046/j.1365-2958.1998.00832.x · Cited by 93
Analysis of random and site‐directed mutations in rhlI, a Pseudomonas aeruginosa gene encoding an acylhomoserine lactone synthase
Parsek, M. R., Schaefer, A. L., & Greenberg, E. P. (1997) · Molecular Microbiology · doi:10.1046/j.1365-2958.1997.5741935.x · Cited by 93
Effect of Varidase (Streptodornase) on Biofilm Formed by Pseudomonas aeruginosa
Nemoto, K., Hirota, K., Murakami, K., Taniguti, K., Murata, H., Vidučić, D., & Miyake, Y. (2003) · Chemotherapy · doi:10.1159/000070617 · Cited by 91
sinI- andexpR-Dependent Quorum Sensing inSinorhizobium meliloti
Gao, M., Chen, H., Eberhard, A., et al. (2005) · Journal of Bacteriology · doi:10.1128/jb.187.23.7931-7944.2005 · Cited by 91
The Global Regulator Genes from Biocontrol Strain Serratia plymuthica IC1270: Cloning, Sequencing, and Functional Studies
Ovadis, M. I., Liu, X., Gavriel, S., Ismailov, Z. F., Chet, I., & Chernin, L. S. (2004) · Journal of Bacteriology · doi:10.1128/jb.186.15.4986-4993.2004 · Cited by 90
The PmlI-PmlR Quorum-Sensing System in Burkholderia pseudomallei Plays a Key Role in Virulence and Modulates Production of the MprA Protease
Valade, E., Thibault, F., Gauthier, Y. P., Palencia, M., Popoff, M. Y., & Vidal, D. R. (2004) · Journal of Bacteriology · doi:10.1128/jb.186.8.2288-2294.2004 · Cited by 87
The toxbox: specific DNA sequence requirements for activation of Vibrio cholerae virulence genes by ToxT
Withey, J. H., & DiRita, V. J. (2006) · Molecular Microbiology · doi:10.1111/j.1365-2958.2006.05053.x · Cited by 87
Antibiotic Therapy for Chronic Infection of Pseudomonas in the Lung
Høiby, N. (1993) · Annual Review of Medicine · doi:10.1146/annurev.me.44.020193.000245 · Cited by 81
The chemistry of protein synthesis and voyage through the ribosomal tunnel
Jenni, S., & Ban, N. (2003) · Current Opinion in Structural Biology · doi:10.1016/s0959-440x(03)00034-4 · Cited by 79
Quorum-Sensing System and Stationary-Phase Sigma Factor ( rpoS ) of the Onion Pathogen Burkholderia cepacia Genomovar I Type Strain, ATCC 25416
Aguilar, C., Bertani, I., & Venturi, V. (2003) · Applied and Environmental Microbiology · doi:10.1128/aem.69.3.1739-1747.2003 · Cited by 79
AHL communication is a widespread phenomenon in biomining bacteria and seems to be involved in mineral-adhesion efficiency
Ruíz, L. M., Valenzuela, S. V., Castro, M., González, A., Frezza, M., Soulère, L., Rohwerder, T., Queneau, Y., Doutheau, A., Sand, W., et al. (2008) · Hydrometallurgy · doi:10.1016/j.hydromet.2008.05.028 · Cited by 76
Quorum sensing in halophilic bacteria: detection of N-acyl-homoserine lactones in the exopolysaccharide-producing species of Halomonas
Llamas, I., Quesada, E., Martínez-Cánovas, M. J., et al. (2005) · Extremophiles · doi:10.1007/s00792-005-0448-1 · Cited by 68

Ecology of Cyanobacteria II: Their Diversity in Space and Time
(2012) · doi:10.1007/978-94-007-3855-3 · Cited by 1,078
Bacterial Biofilm Eradication Agents: A Current Review
Verderosa, A. D., Totsika, M., & Fairfull-Smith, K. E. (2019) · Frontiers in Chemistry · doi:10.3389/fchem.2019.00824 · Cited by 555
Volatile Mediated Interactions Between Bacteria and Fungi in the Soil
Effmert, U., Kalderás, J., Warnke, R., & Piechulla, B. (2012) · Journal of Chemical Ecology · doi:10.1007/s10886-012-0135-5 · Cited by 526
Microalgal-bacterial consortia: From interspecies interactions to biotechnological applications
Zhang, B., Li, W., Guo, Y., Zhang, Z., Shi, W., Cui, F., Lens, P. N. L., & Tay, J. H. (2020) · Renewable and Sustainable Energy Reviews · doi:10.1016/j.rser.2019.109563 · Cited by 441
Biofilm formation and control strategies of foodborne pathogens: food safety perspectives
Zhao, X., Zhao, F., Wang, J., & Zhong, N. (2017) · RSC Advances · doi:10.1039/c7ra02497e · Cited by 283

See all 355

Authors: Dickschat, J. S.
Venue: Natural Product Reports
Publisher: Royal Society of Chemistry (RSC)
Published: 2010
Volume: 27
Issue: 3
Pages: 343
ISSN: 0265-0568 (ISSN-L)
1460-4752
DOI: 10.1039/b804469b
OpenAlex: W2136665929
Cited by: 355
References: 224
FWCI: 11.70
Type: journal article
Language: en
Open access: closed

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.

Quorum sensing and bacterial biofilms

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Self-check

Citations

Cites

Cited by

Metadata

Record

About these checks

Data sources