Safety, activity, and immune correlates of anti–PD-1 antibody in cancer

Topalian, Suzanne L., Hodi, F. Stephen, Brahmer, Julie R., Gettinger, Scott N., Smith, David C., McDermott, David F., Powderly, John D., Carvajal, Richard D. +22 more·2012·New England Journal of Medicine

Cited by (388)

Items 301–388 of 388

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  13. Interaction of bacterial genera associated with therapeutic response to immune checkpoint PD-1 blockade in a United States cohort
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  14. Gastrointestinal toxicity of immune checkpoint inhibitors: From mechanisms to management
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  15. The Cellular Immunotherapy Revolution: Arming the Immune System for Precision Therapy
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  16. Predictors of Response and Survival in Immune Checkpoint Inhibitor-Treated Unresectable Hepatocellular Carcinoma
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  18. Tumor vasculature normalization by orally fed erlotinib to modulate the tumor microenvironment for enhanced cancer nanomedicine and immunotherapy
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  23. Epitope spreading toward wild-type melanocyte-lineage antigens rescues suboptimal immune checkpoint blockade responses
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  30. Immunotherapy via PD-L1–presenting biomaterials leads to long-term islet graft survival
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  32. Primary and acquired resistance to EGFR-targeted therapies in colorectal cancer: impact on future treatment strategies
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  33. Clonality of CD4+ Blood T Cells Predicts Longer Survival With CTLA4 or PD-1 Checkpoint Inhibition in Advanced Melanoma
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  34. Kras and tumor immunity: friend or foe?
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  35. Haematological malignancies: at the forefront of immunotherapeutic innovation
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  36. The role of DNA damage repair (DDR) system in response to immune checkpoint inhibitor (ICI) therapy
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  39. Anti-PD1-Induced Immune-Related Adverse Events and Survival Outcomes in Advanced Melanoma
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  40. Circulating L-arginine predicts the survival of cancer patients treated with immune checkpoint inhibitors
    Peyraud, F., Guégan, J.-P., Bodet, D., Nafia, I., Fontan, L., Auzanneau, C., Cousin, S., Roubaud, G., Cabart, M., Chomy, F. et al. · 2022 · Annals of Oncology
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  43. <i>Faecalibacterium prausnitzii</i> strain EXL01 boosts efficacy of immune checkpoint inhibitors
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  44. Delayed immune-related adverse events in assessment for dose-limiting toxicity in early phase immunotherapy trials
    Kanjanapan, Y., Day, D., Butler, M.O., Wang, L., Joshua, A.M., Hogg, D., Leighl, N.B., Razak, A.R. Abdul, Hansen, A.R., Boujos, S. et al. · 2019 · European Journal of Cancer
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  46. Infiltration of PD-1-positive cells in combination with tumor site PD-L1 expression is a positive prognostic factor in cutaneous angiosarcoma
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  47. Anti-PD-1 Therapy Response Predicted by the Combination of Exosomal PD-L1 and CD28
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  48. PD-1 coinhibitory signals: the link between pathogenesis and protection
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  49. LAG-3 and PD-1+LAG-3 inhibition promote anti-tumor immune responses in human autologous melanoma/T cell co-cultures
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  50. Decreased Suppression and Increased Phosphorylated STAT3 in Regulatory T Cells are Associated with Benefit from Adjuvant PD-1 Blockade in Resected Metastatic Melanoma
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