The DOI matches its Crossref record; 58 of the 58 references it cites were found in a registry or an index.
Nutrition in the Acute Phase of Critical Illness
Open accessAbstract
† No diagram showing how patients were selected was included in the study by Montejo et al. 10 ‡ No information on the way in which investigators concealed study-group assignments was included in the study by Acosta-Escribano et al. 13 § No sample-size calculation and only partial outcome data in the intention-to-treat population were included in the study by Pontes-Arruda et al., 22 and no diagram showing how patients were selected was included in the study by Umpierrez et al. 23¶ The study by Rice et al. 24 was stopped prematurely for futility at the first interim analysis.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“These findings may also explain differences in results of nutritional trials, depending on the clinical setting with several nutritional studies in the ICU setting or in patients with advanced cancer not showing significant benefits form nutrition in regard to clinical outcomes [165,168].”
From ESPEN guideline on nutritional support for polymorbid medical inpatients (2023) · cites this paper as [168]
Experimental — accuracy not yet measuredThe cited source says what the claim attributes to it.
In the citing paper
“Data from studies conducted in the past 10 years challenge the appropriateness of these standard calorie and protein targets during the acute phase of critical illness.8,9”
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Intensive insulin therapy in critically ill patients.
Van den Berghe, G., Wouters, P., Weekers, F., Verwaest, C., Bruyninckx, F., Schetz, M., Vlasselaers, D., Ferdinande, P., Lauwers, P., & Bouillon, R. (2001) · New England Journal of Medicine · doi:10.1056/nejmoa011300 · Cited by 9,977
ESPEN guidelines on parenteral nutrition: intensive care
Singer, P., Berger, M. M., Van den Berghe, G., Biolo, G., Calder, P., Forbes, A., Griffiths, R., Kreyman, G., Leverve, X., & Pichard, C. (2009) · Clinical Nutrition · doi:10.1016/j.clnu.2009.04.024 · Cited by 1,907
Early versus late parenteral nutrition in critically ill adults
Casaer, M. P., Mesotten, D., Hermans, G., Wouters, P. J., Schetz, M., Meyfroidt, G., Van Cromphaut, S., Ingels, C., Meersseman, P., Muller, J., et al. (2011) · New England Journal of Medicine · doi:10.1056/nejmoa1102662 · Cited by 1,696
Self-citationTaylor, B. E., McClave, S. A., Martindale, R. G., Warren, M. M., Johnson, D. R., Braunschweig, C., McCarthy, M. S., Davanos, E., Rice, T. W., Cresci, G. A., et al. (2016) · Critical Care Medicine · doi:10.1097/ccm.0000000000001525 · Cited by 1,476
Increased mortality associated with growth hormone treatment in critically ill adults
Takala, J., Ruokonen, E., Webster, N. R., Nielsen, M. S., Zandstra, D. F., Vundelinckx, G., & Hinds, C. J. (1999) · New England Journal of Medicine · doi:10.1056/nejm199909093411102 · Cited by 1,023
Alberda, C., Gramlich, L., Jones, N., Jeejeebhoy, K., Day, A. G., Dhaliwal, R., & Heyland, D. K. (2009) · Intensive Care Medicine · doi:10.1007/s00134-009-1567-4 · Cited by 975
The National Heart, L., Rice, T. W., Wheeler, A. P., Thompson, B. T., Steingrub, J., Hite, R. D., Moss, M., Morris, A., Dong, N., & Rock, P. (2012) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.2012.137 · Cited by 935
A Randomized Trial of Glutamine and Antioxidants in Critically Ill Patients
Heyland, D., Muscedere, J., Wischmeyer, P. E., Cook, D., Jones, G., Albert, M., Elke, G., Berger, M. M., & Day, A. G. (2013) · New England Journal of Medicine · doi:10.1056/nejmoa1212722 · Cited by 904
INCREASED MORTALITY ASSOCIATED WITH GROWTH HORMONE TREATMENT IN CRITICALLY ILL ADULTS
Akala, J. U. T., Uokonen, E. S. R., Igel, N., Ebster, R. W., Ielsen, M. I. S. N., Andstra, D. U. F. Z., Undelinckx, G. U. V., & Inds, H. J. H. (1999) · Cited by 889
Heidegger, C. P., Berger, M. M., Graf, S., Zingg, W., Darmon, P., Costanza, M. C., Thibault, R., & Pichard, C. (2013) · The Lancet · doi:10.1016/s0140-6736(12)61351-8 · Cited by 776
Research works printed but not linked: 1
- Martin CM, 2004, CMAJ, 170, 197
Cited by
Sorted by citations
Schuetz, P., Fehr, R., Baechli, V., Geiser, M., Deiss, M., Gomes, F., Kutz, A., Tribolet, P., Bregenzer, T., Braun, N., et al. (2019) · The Lancet · doi:10.1016/s0140-6736(18)32776-4 · Cited by 910
Early enteral nutrition in critically ill patients: ESICM clinical practice guidelines
ESICM Working Group on Gastrointestinal Function, Reintam Blaser, A., Starkopf, J., Alhazzani, W., Berger, M. M., Casaer, M. P., Deane, A. M., Fruhwald, S., Hiesmayr, M., Ichai, C., et al. (2017) · Intensive Care Medicine · doi:10.1007/s00134-016-4665-0 · Cited by 837
Self-citationReignier, J., Boisramé-Helms, J., Brisard, L., Lascarrou, J.-B., Ait Hssain, A., Anguel, N., Argaud, L., Asehnoune, K., Asfar, P., Bellec, F., et al. (2018) · The Lancet · doi:10.1016/s0140-6736(17)32146-3 · Cited by 595
Rahman, A., Hasan, R. M., Agarwala, R., Martin, C. M., Day, A. G., & Heyland, D. K. (2015) · Clinical Nutrition · doi:10.1016/j.clnu.2015.01.015 · Cited by 550
Opposing Effects of Fasting Metabolism on Tissue Tolerance in Bacterial and Viral Inflammation
Wang, A., Huen, S. C., Luan, H. H., Yu, S., Zhang, C., Gallezot, J.-D., Booth, C. J., & Medzhitov, R. (2016) · Cell · doi:10.1016/j.cell.2016.07.026 · Cited by 579
Thyroid function in critically ill patients
Fliers, E., Bianco, A. C., Langouche, L., & Boelen, A. (2015) · The Lancet Diabetes & Endocrinology · doi:10.1016/s2213-8587(15)00225-9 · Cited by 441
The Sick and the Weak: Neuropathies/Myopathies in the Critically Ill
Friedrich, O., Reid, M. B., den Berghe, G. V., Vanhorebeek, I., Hermans, G., Rich, M. M., & Larsson, L. (2015) · Physiological Reviews · doi:10.1152/physrev.00028.2014 · Cited by 409
Elke, G., van Zanten, A. R. H., Lemieux, M., McCall, M., Jeejeebhoy, K. N., Kott, M., Jiang, X., Day, A. G., & Heyland, D. K. (2016) · Critical Care · doi:10.1186/s13054-016-1298-1 · Cited by 378
Endothelial barrier dysfunction in septic shock
Opal, S. M., & van der Poll, T. (2014) · Journal of Internal Medicine · doi:10.1111/joim.12331 · Cited by 372
Early versus On-Demand Nasoenteric Tube Feeding in Acute Pancreatitis
Bakker, O. J., van Brunschot, S., van Santvoort, H. C., Besselink, M. G., Bollen, T. L., Boermeester, M. A., Dejong, C. H., van Goor, H., Bosscha, K., Ali, U. A., et al. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1404393 · Cited by 339
Surviving sepsis campaign: research priorities for sepsis and septic shock
Coopersmith, C. M., Backer, D. D., Deutschman, C. S., Ferrer, R., Lat, I., Machado, F. R., Martin, G. S., Martín‐Loeches, I., Nunnally, M., Antonelli, M. M., et al. (2018) · Intensive Care Medicine · doi:10.1007/s00134-018-5175-z · Cited by 292
Reignier, J., Plantefeve, G., Mira, J.-P., Argaud, L., Asfar, P., Aissaoui, N., Badie, J., Botoc, N.-V., Brisard, L., Bui, H.-N., et al. (2023) · The Lancet Respiratory Medicine · doi:10.1016/s2213-2600(23)00092-9 · Cited by 270
Merker, M., Felder, M., Gueissaz, L., Bolliger, R., Tribolet, P., Kägi-Braun, N., Gomes, F., Hoess, C., Pavlicek, V., Bilz, S., et al. (2020) · JAMA Network Open · doi:10.1001/jamanetworkopen.2020.0663 · Cited by 262
Inflammation and nutrition: friend or foe?
Stumpf, F., Keller, B., Gressies, C., & Schuetz, P. (2023) · Nutrients · doi:10.3390/nu15051159 · Cited by 213
Acute Inflammation and Metabolism
Varela, M., Mogildea, M., Moreno, I., & Lopes, A. L. N. (2018) · Inflammation · doi:10.1007/s10753-018-0739-1 · Cited by 224
Pathophysiology of Critical Illness and Role of Nutrition
Sharma, K., Mogensen, K. M., & Robinson, M. K. (2018) · Nutrition in Clinical Practice · doi:10.1002/ncp.10232 · Cited by 194
Wei, X., Day, A. G., Ouellette-Kuntz, H., & Heyland, D. K. (2015) · Critical Care Medicine · doi:10.1097/ccm.0000000000001000 · Cited by 187
Moreno, C., Deltenre, P., Senterre, C., Louvet, A., Gustot, T., Bastens, B., Hittelet, A., Piquet, M., Laleman, W., Orlent, H., et al. (2016) · Gastroenterology · doi:10.1053/j.gastro.2015.12.038 · Cited by 173
Vanhorebeek, I., Verbruggen, S. C. A. T., Casaer, M. P., Gunst, J., Wouters, P. J., Hanot, J., Guerra, G. G., Vlasselaers, D., Joosten, K., & den Berghe, G. V. (2017) · The Lancet Respiratory Medicine · doi:10.1016/s2213-2600(17)30186-8 · Cited by 166
Self-citationAdequate Nutrition May Get You Home
Yeh, D. D., Fuentes, E., Quraishi, S. A., Cropano, C. M., Kaafarani, H. M. A., Lee, J., King, D. R., DeMoya, M. A., Fagenholz, P. J., Butler, K. L., et al. (2015) · Journal of Parenteral and Enteral Nutrition · doi:10.1177/0148607115585142 · Cited by 150
Gastric residual volume in critically ill patients: a dead marker or still alive?
Elke, G., Felbinger, T., & Heyland, D. (2015) · Nutrition in clinical practice · doi:10.1177/0884533614562841 · Cited by 124
Monitoring nutrition in the ICU
Berger, M. M., Reintam-Blaser, A., Calder, P. C., Casaer, M., Hiesmayr, M. J., Mayer, K., Montejo, J. C., Pichard, C., Preiser, J.-C., van Zanten, A. R. H., et al. (2019) · Clinical Nutrition · doi:10.1016/j.clnu.2018.07.009 · Cited by 171
Self-citationLeone, M., Bechis, C., Baumstarck, K., Ouattara, A., Collange, O., Augustin, P., Annane, D., Arbelot, C., Asehnoune, K., Baldési, O., et al. (2015) · Intensive Care Medicine · doi:10.1007/s00134-015-3690-8 · Cited by 162
Bally, M. R., Blaser Yildirim, P. Z., Bounoure, L., Gloy, V. L., Mueller, B., Briel, M., & Schuetz, P. (2016) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2015.6587 · Cited by 159
Meyfroidt, G., Gunst, J., Martín‐Loeches, I., Smith, M., Robba, C., Taccone, F. S., & Citerio, G. (2019) · Intensive Care Medicine · doi:10.1007/s00134-019-05551-y · Cited by 139
Evaluation of Nutritional Support and In-Hospital Mortality in Patients With Malnutrition
Kaegi-Braun, N., Mueller, M., Schuetz, P., Mueller, B., & Kutz, A. (2021) · JAMA Network Open · doi:10.1001/jamanetworkopen.2020.33433 · Cited by 126
Human Protein and Amino Acid Requirements
Hoffer, L. J. (2016) · Journal of Parenteral and Enteral Nutrition · doi:10.1177/0148607115624084 · Cited by 124
Surviving Sepsis Campaign: Research Priorities for Sepsis and Septic Shock
Coopersmith, C. M., Backer, D. D., Deutschman, C. S., Ferrer, R., Lat, I., Machado, F. R., Martin, G. S., Martín‐Loeches, I., Nunnally, M., Antonelli, M. M., et al. (2018) · Critical Care Medicine · doi:10.1097/ccm.0000000000003225 · Cited by 117
Enhanced Recovery After Surgery
Steenhagen, E. (2015) · Nutrition in Clinical Practice · doi:10.1177/0884533615622640 · Cited by 115
Wischmeyer, P. E. (2017) · Critical Care Clinics · doi:10.1016/j.ccc.2017.08.008 · Cited by 118
Marik, P. E., & Hooper, M. H. (2016) · Intensive Care Medicine · doi:10.1007/s00134-015-4131-4 · Cited by 109
ESPEN guideline on nutritional support for polymorbid medical inpatients
Wunderle, C., Gomes, F., Schuetz, P., Stumpf, F., Austin, P., Ballesteros-Pomar, M. D., Cederholm, T., Fletcher, J., Laviano, A., Norman, K., et al. (2023) · Clinical Nutrition · doi:10.1016/j.clnu.2023.06.023 · Cited by 105
“These fi ndings may also explain differences in results of nutritional trials, depending on the clinical setting with several nutritional studies in the ICU setting or in patients with advanced cancer not showing signi fi cant bene fi ts form nutrition in regard to clinical outcomes [165,168].”
Hernández-Tejedor, A., Peñuelas, Ó., Sirgo, G., Llompart-Pou, J. A., Herrejon, E. P., Estella, Á., Cabanes, M. P. F., Alcalá-Llorente, M. A., Galleymore, P. R., Azuara, B. O., et al. (2017) · Medicina Intensiva · doi:10.1016/j.medin.2017.03.004 · Cited by 105
on behalf of the Enhanced Recovery After Critical Illness Programme Group (ERACIP) investigators, Bear, D. E., Wandrag, L., Merriweather, J. L., Connolly, B. A., Hart, N., & Grocott, M. P. W. (2017) · Critical Care · doi:10.1186/s13054-017-1810-2 · Cited by 108
Metabolism, Metabolomics, and Nutritional Support of Patients with Sepsis
Englert, J. A., & Rogers, A. J. (2016) · Clinics in Chest Medicine · doi:10.1016/j.ccm.2016.01.011 · Cited by 102
Plasma Transthyretin as a Biomarker of Lean Body Mass and Catabolic States
Ingenbleek, Y., & Bernstein, L. H. (2015) · Advances in Nutrition · doi:10.3945/an.115.008508 · Cited by 101
Therapeutic management of peritonitis: a comprehensive guide for intensivists
Montravers, P., Blot, S. I., Dimopoulos, G., Eckmann, C., Eggimann, P., Guirao, X., Paiva, J. A., Sganga, G., & Waele, J. J. D. (2016) · Intensive Care Medicine · doi:10.1007/s00134-016-4307-6 · Cited by 103
Metabolic Adaptations to Infections at the Organismal Level
Troha, K., & Ayres, J. S. (2020) · Trends in Immunology · doi:10.1016/j.it.2019.12.001 · Cited by 100
Acquired Muscle Weakness in the Surgical Intensive Care Unit
Farhan, H. N., Moreno‐Duarte, I., Latronico, N., ZAFONTE, R. D., & Eikermann, M. (2015) · Anesthesiology · doi:10.1097/aln.0000000000000874 · Cited by 104
ICU Admission Muscle and Fat Mass, Survival, and Disability at Discharge
Jaitovich, A., Khan, M. M. H. S., Itty, R., Chieng, H., Dumas, C. L., Nadendla, P., Fantauzzi, J. P., Yucel, R. M., Feustel, P. J., & Judson, M. A. (2018) · CHEST Journal · doi:10.1016/j.chest.2018.10.023 · Cited by 97
Sarcopenia and Critical Illness
Hanna, J. (2015) · Journal of Parenteral and Enteral Nutrition · doi:10.1177/0148607114567710 · Cited by 93
Sepsis and Septic Shock Strategies
Armstrong, B., Betzold, R., & May, A. K. (2017) · Surgical Clinics of North America · doi:10.1016/j.suc.2017.07.003 · Cited by 88
Bretscher, C., Boesiger, F., Kaegi-Braun, N., Hersberger, L., Lobo, D. N., Evans, D. C., Tribolet, P., Gomes, F., Hoess, C., Pavlicek, V., et al. (2022) · eClinicalMedicine · doi:10.1016/j.eclinm.2022.101301 · Cited by 88
Nutrition in critical illness: a current conundrum
Hoffer, L. J., & Bistrian, B. R. (2016) · F1000Research · doi:10.12688/f1000research.9278.1 · Cited by 79
Canales, C., Elsayes, A., Yeh, D. D., Belcher, D. M., Nakayama, A., McCarthy, C. M., Chokengarmwong, N., & Quraishi, S. A. (2018) · Journal of Parenteral and Enteral Nutrition · doi:10.1002/jpen.1181 · Cited by 80
Toward nutrition improving outcome of critically ill patients: How to interpret recent feeding RCTs?
Gunst, J., Casaer, M. P., Preiser, J., Reignier, J., & den Berghe, G. V. (2023) · Critical Care · doi:10.1186/s13054-023-04317-9 · Cited by 80
Self-citationWorldwide Survey of Nutritional Practices in PICUs*
Kerklaan, D., Fivez, T., Mehta, N. M., Mesotten, D., van Rosmalen, J., Hulst, J. M., den Berghe, G. V., Joosten, K., & Verbruggen, S. C. A. T. (2015) · Pediatric Critical Care Medicine · doi:10.1097/pcc.0000000000000542 · Cited by 74
Efficacy and Safety of Glutamine-supplemented Parenteral Nutrition in Surgical ICU Patients
Ziegler, T. R., May, A. K., Hebbar, G., Easley, K. A., Griffith, D. P., Dave, N. J., Collier, B. R., Cotsonis, G., Hao, L., Leong, T. L., et al. (2015) · Annals of Surgery · doi:10.1097/sla.0000000000001487 · Cited by 74
Feeding intolerance in critically ill patients with COVID-19
Liu, R., Paz, M., Siraj, L., Boyd, T., Salamone, S., Lite, T.-L. V., Leung, K. M., Chirinos, J. D., Shang, H. H., Townsend, M. J., et al. (2022) · Clinical Nutrition · doi:10.1016/j.clnu.2021.03.033 · Cited by 54
Glucose homeostasis, nutrition and infections during critical illness
Ingels, C., Vanhorebeek, I., & den Berghe, G. V. (2017) · Clinical Microbiology and Infection · doi:10.1016/j.cmi.2016.12.033 · Cited by 73
Heyland, D. K., Day, A. G., Clarke, G., Hough, C. L., Files, D. C., Mourtzakis, M., Deutz, N. E. P., Needham, D. M., & Stapleton, R. (2019) · BMJ Open · doi:10.1136/bmjopen-2018-027893 · Cited by 73
Tian, F., Wang, X., Gao, X., Wan, X., Wu, C., Zhang, L., Li, N., & Li, J. (2015) · Critical Care · doi:10.1186/s13054-015-0902-0 · Cited by 71
Endocrine and Metabolic Alterations in Sepsis and Implications for Treatment
Ingels, C., Gunst, J., & den Berghe, G. V. (2017) · Critical Care Clinics · doi:10.1016/j.ccc.2017.08.006 · Cited by 69
Inflammation and response to nutrition interventions
Wunderle, C., Stumpf, F., & Schuetz, P. (2024) · Journal of Parenteral and Enteral Nutrition · doi:10.1002/jpen.2534 · Cited by 65
Kaegi-Braun, N., Tribolet, P., Baumgartner, A., Fehr, R., Baechli, V., Geiser, M., Deiss, M., Gomes, F., Kutz, A., Hoess, C., et al. (2021) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/nqab042 · Cited by 67
for the OUTCOMEREA study group, Terzi, N., Darmon, M., Reignier, J., Ruckly, S., Garrouste-Orgeas, M., Lautrette, A., Azoulay, É., Mourvillier, B., Argaud, L., et al. (2017) · Critical Care · doi:10.1186/s13054-017-1867-y · Cited by 70
Heyland, D. K., Patel, J. J., Bear, D. E., Sacks, G. S., Nixdorf, H., Dolan, J., Aloupis, M., Licastro, K., Jovanović, V., Rice, T. W., et al. (2018) · Journal of Parenteral and Enteral Nutrition · doi:10.1002/jpen.1449 · Cited by 62
Glenn, T. C., Martin, N. A., McArthur, D. L., Hovda, D. A., Vespa, P. M., Johnson, M. L., Horning, M. A., & Brooks, G. A. (2014) · Journal of Neurotrauma · doi:10.1089/neu.2014.3482 · Cited by 56
Thiessen, S., den Berghe, G. V., & Vanhorebeek, I. (2017) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2017.02.015 · Cited by 55
Lewis, S. R., Schofield-Robinson, O. J., Alderson, P., & Smith, A. F. (2018) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012276.pub2 · Cited by 118
Rahman, A., Agarwala, R., Martin, C. M., Nagpal, D., Teitelbaum, M., & Heyland, D. K. (2016) · Journal of Parenteral and Enteral Nutrition · doi:10.1177/0148607116661839 · Cited by 52
ESPEN practical guideline: Nutritional support for polymorbid medical inpatients
Wunderle, C., Gomes, F., Schüetz, P., Stumpf, F., Austin, P. D., Ballesteros-Pomar, M. D., Cederholm, T., Fletcher, J. M., Laviano, A., Norman, K., et al. (2024) · Clinical Nutrition · doi:10.1016/j.clnu.2024.01.008 · Cited by 51
Nutritional Support in the ICU
Reignier, J., Rice, T. W., Arabi, Y. M., & Casaer, M. P. (2025) · BMJ · doi:10.1136/bmj-2023-077979 · Cited by 57
Self-citationNutritional Management of Medical Inpatients
Reber, E., Gomes, F., Bally, L., Schuetz, P., & Stanga, Z. (2019) · Journal of Clinical Medicine · doi:10.3390/jcm8081130 · Cited by 36
Lin, Y., Wang, M., Sun, N., Liu, Y., Yin, T., & Chen, C. (2019) · PLoS ONE · doi:10.1371/journal.pone.0213076 · Cited by 43
Continuous renal replacement therapy: a potential source of calories in the critically ill,
New, A. M., Nystrom, E. M., Frazee, E., Dillon, J. J., KASHANI, K. B., & Miles, J. M. (2017) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.116.139014 · Cited by 43
Nutrition for the older adult – Current concepts. Report from an ESPEN symposium
Volkert, D., Delzenne, N. M., Demirkan, K., Schneider, S., Abbasoğlu, O., Bahat, G., Barazzoni, R., Bauer, J. M., Cuerda, C., de van der Schueren, M. A. E., et al. (2024) · Clinical Nutrition · doi:10.1016/j.clnu.2024.06.020 · Cited by 52
Hernández-Tejedor, A., Peñuelas, Ó., Sirgo, G., Llompart-Pou, J. A., Herrejon, E. P., Estella, Á., Cabanes, M. P. F., Alcalá-Llorente, M. A., Galleymore, P. R., Azuara, B. O., et al. (2017) · Medicina Intensiva (English Edition) · doi:10.1016/j.medine.2017.03.008 · Cited by 37
Orinovsky, I., & Raizman, E. (2018) · Critical Care Nurse · doi:10.4037/ccn2018433 · Cited by 41
Nutrition in the Acute Phase of Critical Illness
Moss, J., & Patel, P. (2014) · New England Journal of Medicine · doi:10.1056/nejmc1404896 · Cited by 37
Japanese Guidelines for Nutrition Support Therapy in the Adult and Pediatric Critically Ill Patients
日本集中治療医学会重症患者の栄養管理ガイドライン作成委員会 (2016) · Journal of the Japanese Society of Intensive Care Medicine · doi:10.3918/jsicm.23.185 · Cited by 36
Nutritional support in critical illness and recovery
Casaer, M. P., & Ziegler, T. R. (2015) · The Lancet Diabetes & Endocrinology · doi:10.1016/s2213-8587(15)00222-3 · Cited by 37
Self-citationMuscle weakness and nutrition therapy in ICU
Casaer, M. P. (2015) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/mco.0000000000000150 · Cited by 35
Self-citationWunderle, C., Martin, E., Wittig, A., Tribolet, P., Lutz, T. A., Köster-Hegmann, C., Stanga, Z. G., Müeller, B., & Schüetz, P. (2025) · Journal of Inflammation · doi:10.1186/s12950-025-00442-0 · Cited by 33
Clinical Nutrition of Critically Ill Patients in the Context of the Latest ESPEN Guidelines
Gostyńska, A., Stawny, M., Dettlaff, K., & Jelińska, A. (2019) · Medicina · doi:10.3390/medicina55120770 · Cited by 34
Toward Precision in Nutrition Therapy
Stoppe, C., Hill, A., Christopher, K. B., & Kristof, A. S. (2024) · Critical Care Medicine · doi:10.1097/ccm.0000000000006537 · Cited by 33
Gutierrez, A., Carlson, C., Kalra, R., Elliott, A. M., Yannopoulos, D., & Bartos, J. A. (2021) · Resuscitation · doi:10.1016/j.resuscitation.2021.04.029 · Cited by 30
Implementation of enteral feeding protocol in an intensive care unit: Before-and-after study
Padar, M., Uusvel, G., Starkopf, L., Starkopf, J., & Blaser, A. R. (2017) · World Journal of Critical Care Medicine · doi:10.5492/wjccm.v6.i1.56 · Cited by 33
Are Predictive Energy Expenditure Equations in Ventilated Surgery Patients Accurate?
Tignanelli, C. J., Andrews, A. G., Sieloff, K. M., Pleva, M. R., Reichert, H. A., Wooley, J. A., Napolitano, L. M., & Cherry‐Bukowiec, J. R. (2017) · Journal of Intensive Care Medicine · doi:10.1177/0885066617702077 · Cited by 30
A J-shaped relationship between caloric intake and survival in critically ill patients
Crosara, I. C. R., Mélot, C., & Preiser, J.-C. (2015) · Annals of Intensive Care · doi:10.1186/s13613-015-0079-3 · Cited by 29
Oral Nutrition during and after Critical Illness: SPICES for Quality of Care!
Fadeur, M., Preiser, J., Verbrugge, A., Misset, B., & Rousseau, A. (2020) · Nutrients · doi:10.3390/nu12113509 · Cited by 29
Besecker, E. M., Deiter, G. M., Pironi, N., Cooper, T. K., & Holmes, G. M. (2016) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00347.2016 · Cited by 30
Evidence-based nutrition for the malnourished, hospitalised patient: one bite at a time
Merker, M., Gomes, F., Stanga, Z. G., & Schüetz, P. (2019) · Swiss Medical Weekly · doi:10.4414/smw.2019.20112 · Cited by 28
What is the best nutritional support for critically ill patients?
Hoffer, L. J., & Bistrian, B. R. (2014) · Europe PMC (PubMed Central) · doi:10.3978/j.issn.2304-3881.2014.08.03 · Cited by 27
Schüetz, P. (2017) · BMC Medicine · doi:10.1186/s12916-017-0812-x · Cited by 28
Lipid metabolic signatures deviate in sepsis survivors compared to non-survivors
Khaliq, W., Großmann, P., Neugebauer, S., Kleyman, A., Domizi, R., Calcinaro, S., Brealey, D. A., Gräler, M. H., Kiehntopf, M., Schäuble, S., et al. (2020) · Computational and Structural Biotechnology Journal · doi:10.1016/j.csbj.2020.11.009 · Cited by 28
Post-Cardiac Arrest Care in Adult Patients After Extracorporeal Cardiopulmonary Resuscitation
Kang, J. K., Darby, Z. E., Bleck, T. P., Whitman, G. J. R., Kim, B. S., & Cho, S. (2023) · Critical Care Medicine · doi:10.1097/ccm.0000000000006102 · Cited by 26
Casaer, M. P., Stragier, H., Hermans, G., Hendrickx, A., Wouters, P. J., Dubois, J., Güiza, F., den Berghe, G. V., & Gunst, J. (2024) · Intensive Care Medicine · doi:10.1007/s00134-024-07546-w · Cited by 26
Self-citationTamiya, H., Yasunaga, H., Matusi, H., Fushimi, K., Akishita, M., & Ogawa, S. (2015) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.115.111831 · Cited by 26
Prescribed hypocaloric nutrition support for critically-ill adults
Perman, M., Ciapponi, A., Franco, J. V. A., Loudet, C., Crivelli, A., Garrote, V., & Perman, G. (2018) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007867.pub2 · Cited by 25
Protein requirement in critical illness
Hoffer, L. J. (2015) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2015-0551 · Cited by 26
Should enteral nutrition be started in the first week of critical illness?
Martindale, R. G., & Warren, M. M. (2015) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/mco.0000000000000146 · Cited by 26
Yang, S.-F., Guo, J., Ni, Q., Chen, J.-Q., Guo, X.-J., Xue, G., Ye, M., & Zhang, L. (2017) · Clinical Nutrition · doi:10.1016/j.clnu.2017.12.008 · Cited by 24
Inflammation reduces the effect of nutritional therapy on clinical outcomes in cancer patients
Bargetzi, L., Bargetzi, M., Laviano, A., Stanga, Z., & Schuetz, P. (2021) · Annals of Oncology · doi:10.1016/j.annonc.2021.08.1989 · Cited by 26
Shi, J., Wei, L., Huang, R., & Liao, L. (2018) · Medicine · doi:10.1097/md.0000000000011874 · Cited by 25
Joo, W. J., Ide, K., Kawasaki, Y., Takeda, C., Seki, T., Usui, T., & Kawakami, K. (2019) · Resuscitation · doi:10.1016/j.resuscitation.2019.01.007 · Cited by 25
Evaluation of implementation of fasting guidelines for enterally fed critical care patients
Jenkins, B., Calder, P. C., & Marino, L. V. (2018) · Clinical Nutrition · doi:10.1016/j.clnu.2018.01.024 · Cited by 25
Evidence for the use of parenteral nutrition in the pediatric intensive care unit
Fivez, T., Kerklaan, D., Mesotten, D., Verbruggen, S. C. A. T., Joosten, K., & den Berghe, G. V. (2015) · Clinical Nutrition · doi:10.1016/j.clnu.2015.11.004 · Cited by 25
Koontalay, A., Sangsaikaew, A., & Khamrassame, A. (2019) · Asian Nursing Research · doi:10.1016/j.anr.2019.12.001 · Cited by 29
Parenteral nutrition: never say never
Oshima, T., & Pichard, C. (2015) · Critical Care · doi:10.1186/cc14723 · Cited by 24
Metadata
- Authors
- Casaer, M. P., & Van den Berghe, G.
- Affiliations
- KU Leuven (BE)
- ORCID
- Casaer, Michael P.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2014-03-27
- Volume
- 370
- Issue
- 13
- Pages
- 1227-1236
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2167108605
- Semantic Scholar
- 0cb329f79bd3d2161f4d43c16bc04bf14fe369d7
- Cited by
- 335
- References
- 58
- Citations by year
- 2026: 17 · 2025: 18 · 2024: 18 · 2023: 17 · 2022: 24 · 2021: 29 · 2020: 23 · 2019: 23 · 2018: 30 · 2017: 34 · 2016: 27 · 2015: 56 · 2014: 18
- FWCI
- 5.12
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Lirias (KU Leuven) (submittedVersion)
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Clinical Nutrition and Gastroenterology
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Health Sciences › Medicine › Critical Care and Intensive Care Medicine › Sepsis Diagnosis and Treatment
- Keywords
- nutrition, critical illness, acute phase, critically ill patients, nutritional support, methodological quality, reporting quality, sample size determination, blinding, early trial termination
- MeSH terms
- Amino Acids, Animals, Anorexia, Enteral Nutrition, Food, Humans, Lipids, Nutritional Requirements, Parenteral Nutrition, Time Factors, Randomized Controlled Trials as Topic, Critical Illness, Micronutrients
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review