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Deep annotation of mouse iso-miR and iso-moR variation
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“However, with the increasing depth of Next Generation Sequencing (NGS) data, scientists have observed that both arms (strands) of the miRNA duplex could be utilized by the RNA-induced silencing complex (RISC) [25,26].”
From Bioinformatic Interrogation of 5p-arm and 3p-arm Specific miRNA Expression Using TCGA Datasets (2015) · cites this paper as [26]
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“Using high-throughput miRNA sequencing information, expression of both the 5p-arm and 3p-arm mature miRNAs were demonstrated and generated from the single miRNA hairpin precursor.”
From Bioinformatic Interrogation of 5p-arm and 3p-arm Specific miRNA Expression Using TCGA Datasets (2015) · cites this paper as [26]
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“It has been reported that isomiRs could also associate with RISC and be involved in the target mRNA silencing [26].”
From Bioinformatic Interrogation of 5p-arm and 3p-arm Specific miRNA Expression Using TCGA Datasets (2015) · cites this paper as [26]
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Citations
Cites
The widespread regulation of microRNA biogenesis, function and decay
Krol, J., Loedige, I., & Filipowicz, W. (2010) · Nature Reviews Genetics · doi:10.1038/nrg2843 · Cited by 4,672
A Mammalian microRNA Expression Atlas Based on Small RNA Library Sequencing
Landgraf, P., Rusu, M., Sheridan, R., Sewer, A., Iovino, N., Aravin, A., Pfeffer, S., Rice, A., Kamphorst, A. O., Landthaler, M., et al. (2007) · Cell · doi:10.1016/j.cell.2007.04.040 · Cited by 3,626
Gene silencing by microRNAs: contributions of translational repression and mRNA decay
Huntzinger, E., & Izaurralde, E. (2011) · Nature Reviews Genetics · doi:10.1038/nrg2936 · Cited by 2,339
MicroRNAs and their isomiRs function cooperatively to target common biological pathways
Cloonan, N., Wani, S., Xu, Q., Gu, J., Lea, K., Heater, S., Barbacioru, C., Steptoe, A. L., Martin, H. C., Nourbakhsh, E., et al. (2011) · Genome Biology · doi:10.1186/gb-2011-12-12-r126 · Cited by 345
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Cited by
Sorted by citations
Regulation of miRNA strand selection: follow the leader?
Meijer, H. A., Smith, E. M., & Bushell, M. (2014) · Biochemical Society Transactions · doi:10.1042/bst20140142 · Cited by 233
Arcila, M. L., Betizeau, M., Cambronne, X. A., Guzman, E., Doerflinger, N., Bouhallier, F., Zhou, H., Wu, B., Rani, N., Bassett, D. S., et al. (2014) · Neuron · doi:10.1016/j.neuron.2014.01.017 · Cited by 80
Self-citationBioinformatic Interrogation of 5p-arm and 3p-arm Specific miRNA Expression Using TCGA Datasets
Kuo, W.-T., Su, M.-W., Lee, Y., Chen, C.-H., Wu, C.-W., Fang, W.-L., Huang, K.-H., & Lin, W.-C. (2015) · Journal of Clinical Medicine · doi:10.3390/jcm4091798 · Cited by 30
Metadata
- Authors
- Zhou, H., Arcila, M. L., Li, Z., Lee, E. J., Henzler, C., Liu, J., Rana, T. M., & Kosik, K. S.
- Venue
- Nucleic Acids Research
- Publisher
- Oxford University Press (OUP)
- Published
- 2012-03-19
- Volume
- 40
- Issue
- 13
- Pages
- 5864-5875
- ISSN
- 1362-4962
- 0305-1048
- PMC
- PMC3401436
- Cited by
- 78
- References
- 4
- Language
- en
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