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Cited by 423

The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.

Emerging endocrine disrupters: perfluoroalkylated substances

Open access
Jensen, Allan Astrup, Leffers, Henrik·2008·International Journal of Andrology
DOI 10.1111/j.1365-2605.2008.00870.x
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Abstract

Summary: In recent years, polyfluorinated chemicals (PFCs) have increasingly been used as surfactants in various industry‐ and consumer products, because of their unique properties as repellents of dirt, water and oils. The most well‐known PFCs are perfluorooctane sulfonic acid (PFOS), perfluorooctanoic acid (PFOA) and their derivatives belonging to the group of perfluoroalkylated substances. The PFCs are very persistent in the environment, and some of them have been discovered as global pollutants of air, water, soil and wildlife and even found in remote polar areas. Bioaccumulation occurs also in humans, and everybody in our society has traces of these PFCs in their blood and internal organs such as the liver, kidneys, spleen, gall bladder and testes. In the blood, PFOS and PFOA are bound to serum proteins. The acute toxicity of the polyfluorinated substances is moderate but some substances can induce peroxisome proliferation in rat livers and may change the fluidity of cell membranes. Some of these PFCs, such as PFOS and PFOA, are potential developmental toxicants and are suspected endocrine disruptors with effects on sex hormone levels resulting in lower testosterone levels and higher oestradiol level. Other PFCs have oestrogenic effects in cell cultures. The industrial production of PFOS and its derivatives stopped in 2000, and the European Union has banned most uses from the summer of 2008. However, hundreds of related chemicals: homologues with shorter or longer alkyl chain, PFOA and telomers, which potentially may degrade to perfluoroalkanoic (carboxylic) acids, are not regulated.

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Show all 10 references

Research works printed but not linked: 75

  1. 10.1136/oem.60.10.722 · DOI
  2. 10.1210/jc.2003-031786 · DOI
  3. 10.1021/es0700911 · DOI
  4. 10.1289/ehp.10334 · DOI · Paper page
  5. 10.1289/ehp.6128 · DOI · Paper page
  6. 10.1289/ehp.115-a250 · DOI
  7. 10.1006/taap.1995.1164 · DOI
  8. 10.1016/j.taap.2004.04.016 · DOI
  9. 10.1016/j.envpol.2004.12.020 · DOI
  10. 10.1016/j.yrtph.2004.03.003 · DOI
  11. 10.1289/ehp.9060 · DOI
  12. 10.1021/es0517973 · DOI
  13. 10.1016/0041-008X(92)90116-A · DOI
  14. Corsolini S., 2004, Perfluorooctane sulfonate and related fluorochemicals in several organisms including humans from Italy, Organohalogen Compounds, 66, 4079
  15. 10.1021/es0600330 · DOI
  16. 10.1016/j.envres.2006.06.008 · DOI · Paper page
  17. 10.1289/ehp.10506 · DOI · Paper page
  18. 10.1093/humrep/deg273 · DOI · Paper page
  19. 10.1007/s00420-006-0136-1 · DOI
  20. 10.1093/toxsci/kfm121 · DOI
  21. 10.1021/es022253t · DOI · Paper page
  22. 10.1039/b412532k · DOI
  23. 10.1289/ehp.9490 · DOI
  24. 10.1016/j.envres.2004.12.003 · DOI · Paper page
  25. 10.1016/j.chemosphere.2006.05.010 · DOI
  26. 10.1007/0-387-21731-2_4 · DOI · Paper page
  27. 10.1093/toxsci/kfl162 · DOI
  28. 10.1002/path.1309 · DOI
  29. 10.1016/S1532-0456(03)00043-7 · DOI · Paper page
  30. 10.1289/ehp.6864 · DOI · Paper page
  31. 10.1065/espr2007.01.384 · DOI
  32. 10.1897/02-553 · DOI · Paper page
  33. 10.1289/ehp.9491 · DOI · Paper page
  34. Kato K., 2007, Serum concentrations of polyfluoroalkyl compounds in Faroe Island residents, Organohalogen Compounds, 69, 161
  35. 10.1039/b314085g · DOI
  36. 10.1021/es040332u · DOI · Paper page
  37. 10.1093/toxsci/kfj105 · DOI · Paper page
  38. 10.1095/biolreprod.104.039404 · DOI
  39. 10.1006/faat.1996.0059 · DOI
  40. 10.1016/j.tox.2005.07.019 · DOI · Paper page
  41. 10.1016/j.tox.2005.07.018 · DOI · Paper page
  42. 10.1093/toxsci/kfm079 · DOI
  43. 10.1007/s00420-006-0165-9 · DOI · Paper page
  44. 10.1021/es011001 · DOI
  45. Odland J. Ø., 2006, Kartlegging av “nye” miljøgifter i human blodprøver fra Nord‐Norge, Nord‐Vest Russland og Sibir
  46. OECD, 2006, Survey on Production and Use of PFOS, PFAS, PFOA, PFCA, Their Related Substances and Products/Mixtures Containing These Substances
  47. 10.1021/es020955c · DOI
  48. 10.1289/ehp.6316 · DOI · Paper page
  49. 10.1016/j.chemosphere.2003.09.025 · DOI
  50. Poulsen P. B., 2005, More Environmentally Friendly Alternatives to PFOS‐Compounds and PFOA. Environmental Project No. 1013.
  51. 10.1021/es0512475 · DOI · Paper page
  52. 10.1016/S0300-483X(02)00511-5 · DOI · Paper page
  53. 10.1016/j.beem.2005.09.005 · DOI · Paper page
  54. 10.1093/toxsci/kfm070 · DOI
  55. 10.1021/es0305555 · DOI · Paper page
  56. Shoeib M., 2007, Indoor air & dust concentration of fluorotelomer alcohols, Organohalogen Compounds, 69, 146
  57. 10.1021/es0101227 · DOI · Paper page
  58. 10.1021/es062377w · DOI
  59. 10.1093/humrep/16.5.972 · DOI · Paper page
  60. 10.1897/04-258R.1 · DOI
  61. 10.1021/es048309w · DOI
  62. 10.1021/es051750h · DOI
  63. 10.1016/0009-2797(95)03630-5 · DOI
  64. 10.1289/ehp.95103s7113 · DOI · Paper page
  65. 10.1021/es0303440 · DOI · Paper page
  66. Thomford P. J., 2002, Terminal observations in Sprague‐Dawley rats after lifetime dietary exposure to N‐ethyl perfluorooctane sulfonamide ethanol, Toxicologist, 66, 185
  67. Thomsen C., 2006, The ranges of polyfluorinated compounds in serum from a group of high consumers of fish in from a contaminated lake in Norway, Organohalogen Compounds, 68, 1701
  68. 10.1289/ehp.6831 · DOI
  69. Tittlemier S., 2004, Presence of anionic perfluorinated organic compounds in serum collected from northern Canadian populations, Organohalogen Compounds, 66, 4009
  70. 10.1021/jf061713p · DOI
  71. UNEP, 2001, Information Kit Stockholm 2001.
  72. US EPA., 2000, Perfluorooctyl sulfonates; proposed significant new use rule, Federal Register, 65, 62319
  73. 10.1016/j.tiv.2006.05.002 · DOI
  74. 10.1021/es051858x · DOI · Paper page
  75. 10.1093/toxsci/kfl177 · DOI

Cited by

Metadata

Authors
Jensen, A. A., & Leffers, H.
Venue
International Journal of Andrology
Publisher
Wiley
Published
2008-03-03
Volume
31
Issue
2
Pages
161-169
ISSN
  • 0105-6263 (ISSN-L)
  • 1365-2605
DOI
10.1111/j.1365-2605.2008.00870.x
OpenAlex
W1997592674
Cited by
423
References
10
FWCI
19.88
Type
journal article
Language
en
Open access
bronze
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor)

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.