Cited by 147Memory and Neural MechanismsMemory Processes and InfluencesStress Responses and Cortisol

Role of the Basolateral Amygdala in Memory Consolidation

McINTYRE, CHRISTA K., POWER, ANN E., ROOZENDAAL, BENNO, McGAUGH, JAMES L.·2003·Annals of the New York Academy of Sciences

Abstract

A bstract:Memories of emotionally arousing events tend to be more vivid and to persist longer than do memories of neutral or trivial events. Moreover, memories of emotionally influenced information may endure after a single experience. Recent findings strongly suggest that the influence of emotional arousal on memory consolidation is mediated by the release of adrenal stress hormones (epinephrine and glucocorticoids) and neurotransmitters that converge in modulating the noradrenergic system within the amygdala. Considerable evidence also indicates that amygdala activation influences memory by regulating consolidation in other brain regions. The findings suggest further that this memory‐modulatory system may be involved in the formation of traumatic memories and posttraumatic stress disorder in human subjects.

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Crossref · 10.1111/j.1749-6632.2003.tb07088.x

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99 of 99 references verified0 citation errors · 0 not checkable

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Authors
McINTYRE, C. K., POWER, A. E., ROOZENDAAL, B., & McGAUGH, J. L.
Affiliations
University of California, Irvine (US)
Corresponding author
McINTYRE, CHRISTA K.
Venue
Annals of the New York Academy of Sciences
Publisher
Wiley
Published
2003-04
Volume
985
Issue
1
Pages
273-293
ISSN
  • 0077-8923 (ISSN-L)
  • 1749-6632
OpenAlex
W2092545125
Cited by
147
References
99
Citations by year
2026: 2 · 2024: 3 · 2023: 2 · 2022: 2 · 2021: 3 · 2020: 3 · 2019: 5 · 2018: 6 · 2017: 6 · 2016: 10 · 2015: 4 · 2014: 6 · 2013: 9 · 2012: 11
FWCI
1.43
Type
journal article
Language
en
Open access
closed
Locations
  • Annals of the New York Academy of Sciences (publishedVersion)
  • PubMed (publishedVersion)
Funders
National Institute of Mental Health (MH12526, F32MH012646, MH 12646)
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Memory Processes and Influences
  • Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
Keywords
basolateral amygdala, memory consolidation, emotional arousal, epinephrine, glucocorticoids, noradrenergic system, stress hormones, traumatic memory, post-traumatic stress disorder, emotional memory
MeSH terms
Amygdala, Animals, Avoidance Learning, Humans, Memory, Models, Neurological, Norepinephrine, Neurotransmitter Agents

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