Resistance training effectiveness on body composition and body weight outcomes in individuals with overweight and obesity across the lifespan: A systematic review and meta-analysis

Lopez, Pedro; Taaffe, Dennis R.; Galvão, Daniel A.; Newton, Robert U.; Nonemacher, Elisa R.; Wendt, Victória M.; Bassanesi, Renata N.; Turella, Douglas J. P.; Rech, Anderson

doi:10.1111/obr.13428

Cited by 210Physical Activity and HealthCardiovascular and exercise physiologyObesity, Physical Activity, Diet

Resistance training effectiveness on body composition and body weight outcomes in individuals with overweight and obesity across the lifespan: A systematic review and meta-analysis

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Lopez, Pedro, Taaffe, Dennis R., Galvão, Daniel A., Newton, Robert U., Nonemacher, Elisa R., Wendt, Victória M., Bassanesi, Renata N., Turella, Douglas J. P. +1 more·2022·Obesity Reviews

DOI 10.1111/obr.13428PMC PMC9285060

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Abstract

Summary: To systematically review and analyze the effects of resistance‐based exercise programs on body composition, regional adiposity, and body weight in individuals with overweight/obesity across the lifespan. Using PRISMA guidelines, randomized controlled trials were searched in nine electronic databases up to December 2020. Meta‐analyses were performed using random‐effects model. One‐hundred sixteen articles describing 114 trials ( n = 4184 participants) were included. Interventions involving resistance training and caloric restriction were the most effective for reducing body fat percentage (ES = −3.8%, 95% CI: −4.7 to −2.9%, p < 0.001) and whole‐body fat mass (ES = −5.3 kg, 95% CI: −7.2 to −3.5 kg, p < 0.001) compared with groups without intervention. Significant results were also observed following combined resistance and aerobic exercise (ES = −2.3% and −1.4 kg, p < 0.001) and resistance training alone (ES = −1.6% and −1.0 kg, p < 0.001) compared with no training controls. Resistance training alone was the most effective for increasing lean mass compared with no training controls (ES = 0.8 kg, 95% CI: 0.6 to 1.0 kg, p < 0.001), whereas lean mass was maintained following interventions involving resistance training and caloric restriction (ES = ~ − 0.3 kg, p = 0.550–0.727). Results were consistently observed across age and sex groups ( p = 0.001–0.011). Reductions in regional adiposity and body weight measures were also observed following combined resistance and aerobic exercise and programs including caloric restriction ( p < 0.001). In conclusion, this study provides evidence that resistance‐based exercise programs are effective and should be considered within any multicomponent therapy program when caloric restriction is utilized in individuals with overweight or obesity.

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Resistance exercise effectively counteracts potential adverse effects of weight loss by reducing lean mass loss and the associated risk of sarcopenia and frailty.
“Several systemic reviews have confirmed that resistance exercise effectively counteracts potential adverse effects of weight loss by reducing lean mass loss and the associated risk of sarcopenia and frailty (34).”
From GLP-1 agonists and exercise: the future of lifestyle prioritization (2025) · cites this paper as [34]
A recent systematic review and meta-analysis concluded that supervised resistance training combined with caloric restriction was effective for lowering body fat percentage (by 2.9-4.7%) in people living with overweight or obesity during weight loss.
“Also, a recent systematic review and meta-analysis concluded that supervised resistance training combined with caloric restriction was effective for lowering body fat percentage (by 2.9–4.7%) in people living with overweight or obesity during weight loss [42].”
From The effects of a home-based resistance training programme on body composition and muscle function during weight loss in people living with overweight or obesity: a randomised controlled pilot trial (2025) · cites this paper as [42]

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“%) in people living with over-weight or obesity during weight loss [42].”
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Moderators of resistance training effects in overweight and obese adults: a systematic review and meta-analysis
LOPEZ, P., RADAELLI, R., TAAFFE, D. R., GALVÃO, D. A., NEWTON, R. U., NONEMACHER, E. R., WENDT, V. M., BASSANESI, R. N., TURELLA, D. J. P., & RECH, A. (2022) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000002984 · Cited by 21 · see citing works
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Resistance Exercise for Body Composition in Children Who Are Overweight or Obese
Rech, A., Radaelli, R., Turella, D. J. P., Nonemacher, E. R., Wendt, V. M., Bassanesi, R. N., Cioato, A. C., Paniz, B. M., & Lopez, P. (2026) · Pediatric Exercise Science · doi:10.1123/pes.2026-0007
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Effects of Resistance Exercise on Total and Regional Body Composition in Overweight Sedentary Males
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Effect of resistance exercise on body composition, muscle strength and cardiometabolic health during dietary weight loss in people living with overweight or obesity: a systematic review and meta-analysis
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Authors: Lopez, P., Taaffe, D. R., Galvão, D. A., Newton, R. U., Nonemacher, E. R., Wendt, V. M., Bassanesi, R. N., Turella, D. J. P., & Rech, A.
Affiliations: Exercise Medicine Research Institute Edith Cowan University Joondalup Western Australia Australia
Edith Cowan University (AU)
Universidade de Caxias do Sul (BR)
ORCID: Lopez, Pedro
Taaffe, Dennis R.
Galvão, Daniel A.
Newton, Robert U.
Turella, Douglas J. P.
Rech, Anderson
Venue: Obesity Reviews
Publisher: Wiley
Published: 2022-02-21
Volume: 23
Issue: 5
Pages: e13428-e13428
ISSN: 1467-7881 (ISSN-L)
1467-789X
DOI: 10.1111/obr.13428
PMC: PMC9285060
OpenAlex: W4213200126
Cited by: 210
References: 157
Citations by year: 2026: 60 · 2025: 60 · 2024: 49 · 2023: 33 · 2022: 8
FWCI: 5.16
Type: journal article
Language: en
Open access: hybrid
doi.org
Licence: cc-by-nc
creativecommons.org/licenses/by-nc/4.0/ (vor)
Locations: Obesity Reviews (publishedVersion, cc-by-nc)
PubMed Central (publishedVersion, cc-by-nc)
PubMed (publishedVersion)
Australasian Journal of Paramedicine (submittedVersion, cc-by-nc)
Funders: Melanoma Centre of Research Excellence
Topics: Health Sciences › Medicine › Physiology › Physical Activity and Health
Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
Keywords: resistance training, body composition, body weight, overweight, obesity, caloric restriction, regional adiposity, fat mass, lean body mass, lifespan, sex differences, age differences
MeSH terms: Body Composition, Body Weight, Humans, Longevity, Obesity, Body Mass Index, Overweight, Resistance Training

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Resistance training effectiveness on body composition and body weight outcomes in individuals with overweight and obesity across the lifespan: A systematic review and meta-analysis

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