Cited by 341Stress Responses and CortisolNeural and Behavioral Psychology StudiesMemory and Neural Mechanisms

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The Biology of Being Frazzled

Arnsten, Amy F. T.·1998·Science

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Abstract

Under stress, our brain works differently. From our own experiences we know this, but now several lines of research are defining the neurobiology behind these changes. In her commentary, Arnsten summarizes recent work that demonstrates that some kinds of memory become enhanced (such as the image of a gruesome accident), while higher order thinking, mediated by a region of the brain called the prefrontal cortex, becomes impaired.

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Authors: Arnsten, A. F. T.
Affiliations: Yale University (US)
Corresponding author: Arnsten, Amy F. T.
ORCID: Arnsten, Amy F. T.
Venue: Science
Publisher: American Association for the Advancement of Science (AAAS)
Published: 1998-06-12
Volume: 280
Issue: 5370
Pages: 1711-1712
ISSN: 0036-8075 (ISSN-L)
1095-9203
DOI: 10.1126/science.280.5370.1711
OpenAlex: W1572413306
Cited by: 341
References: 16
Citations by year: 2026: 3 · 2025: 1 · 2024: 2 · 2023: 10 · 2022: 18 · 2021: 9 · 2020: 14 · 2019: 19 · 2018: 11 · 2017: 12 · 2016: 20 · 2015: 16 · 2014: 13 · 2013: 20 · 2012: 19
FWCI: 3.53
Type: journal article
Language: en
Open access: closed
Locations: Science (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
Keywords: stress, neurobiology of stress, memory enhancement, prefrontal cortex, cognitive impairment, emotional memory, stress hormones
MeSH terms: Amygdala, Animals, Attention, Mental Disorders, Catecholamines, Dopamine, Humans, Memory, Norepinephrine, Receptors, Adrenergic, beta, Stress, Physiological, Prefrontal Cortex, Receptors, Dopamine D1

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