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Regulation of Actin Assembly Associated With Protrusion and Adhesion in Cell Migration
Abstract
To migrate, a cell first extends protrusions such as lamellipodia and filopodia, forms adhesions, and finally retracts its tail. The actin cytoskeleton plays a major role in this process. The first part of this review (sect. ii) describes the formation of the lamellipodial and filopodial actin networks. In lamellipodia, the WASP-Arp2/3 pathways generate a branched filament array. This polarized dendritic actin array is maintained in rapid treadmilling by the concerted action of ADF, profilin, and capping proteins. In filopodia, formins catalyze the processive assembly of nonbranched actin filaments. Cell matrix adhesions mechanically couple actin filaments to the substrate to convert the treadmilling into protrusion and the actomyosin contraction into traction of the cell body and retraction of the tail. The second part of this review (sect. iii) focuses on the function and the regulation of major proteins (vinculin, talin, tensin, and α-actinin) that control the nucleation, the binding, and the barbed-end growth of actin filaments in adhesions.
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Cites
Ridley, A. J., & Hall, A. (1992) · Cell · doi:10.1016/0092-8674(92)90163-7 · Cited by 4,468
Nobes, C. D., & Hall, A. (1995) · Cell · doi:10.1016/0092-8674(95)90370-4 · Cited by 4,412
Cell locomotion and focal adhesions are regulated by substrate flexibility
Pelham, R. J., & Wang, Y.-L. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.25.13661 · Cited by 3,027
Regulation of Myosin Phosphatase by Rho and Rho-Associated Kinase (Rho-Kinase)
Kimura, K., Ito, M., Amano, M., Chihara, K., Fukata, Y., Nakafuku, M., Yamamori, B., Feng, J., Nakano, T., Okawa, K., et al. (1996) · Science · doi:10.1126/science.273.5272.245 · Cited by 2,884
Rho-stimulated contractility drives the formation of stress fibers and focal adhesions.
Chrzanowska-Wodnicka, M., & Burridge, K. (1996) · The Journal of cell biology · doi:10.1083/jcb.133.6.1403 · Cited by 1,683
Mullins, R. D., Heuser, J. A., & Pollard, T. D. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.11.6181 · Cited by 1,433
Regulation of actin dynamics through phosphorylation of cofilin by LIM-kinase
Arber, S., Barbayannis, F. A., Hanser, H., Schneider, C., Stanyon, C. A., Bernard, O., & Caroni, P. (1998) · Nature · doi:10.1038/31729 · Cited by 1,425
Focal Contacts as Mechanosensors
Riveline, D., Zamir, E., Balaban, N. Q., Schwarz, U. S., Ishizaki, T., Narumiya, S., Kam, Z., Geiger, B., & Bershadsky, A. D. (2001) · The Journal of Cell Biology · doi:10.1083/jcb.153.6.1175 · Cited by 1,419
Rohatgi, R., Ma, L., Miki, H., Lopez, M., Kirchhausen, T., Takenawa, T., & Kirschner, M. W. (1999) · Cell · doi:10.1016/s0092-8674(00)80732-1 · Cited by 1,348
Immune cell migration in inflammation: present and future therapeutic targets
Luster, A. D., Alon, R., & von Andrian, U. H. (2005) · Nature Immunology · doi:10.1038/ni1275 · Cited by 1,313
Talin Binding to Integrin ß Tails: A Final Common Step in Integrin Activation
Tadokoro, S., Shattil, S. J., Eto, K., Tai, V., Liddington, R. C., de Pereda, J. M., Ginsberg, M. H., & Calderwood, D. A. (2003) · Science · doi:10.1126/science.1086652 · Cited by 1,209
Svitkina, T. M., & Borisy, G. G. (1999) · The Journal of Cell Biology · doi:10.1083/jcb.145.5.1009 · Cited by 1,180
Molecular complexity and dynamics of cell-matrix adhesions
Zamir, E., & Geiger, B. (2001) · Journal of Cell Science · doi:10.1242/jcs.114.20.3583 · Cited by 1,108
Formation of actin stress fibers and focal adhesions enhanced by Rho-kinase
Amano, M., Chihara, K., Kimura, K., Fukata, Y., Nakamura, N., Matsuura, Y., & Kaibuchi, K. (1997) · Science · doi:10.1126/science.275.5304.1308 · Cited by 1,077
The ARP2/3 complex: an actin nucleator comes of age
Goley, E. D., & Welch, M. D. (2006) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2026 · Cited by 1,063
Carlier, M.-F., Laurent, V., Santolini, J., Melki, R., Didry, D., Xia, G.-X., Hong, Y., Chua, N.-H., & Pantaloni, D. (1997) · The Journal of Cell Biology · doi:10.1083/jcb.136.6.1307 · Cited by 1,049
Self-citationReconstitution of actin-based motility of Listeria and Shigella using pure proteins
Loisel, T. P., Boujemaa, R., Pantaloni, D., & Carlier, M.-F. (1999) · Nature · doi:10.1038/44183 · Cited by 970
Self-citationThe WASP-WAVE protein network: Connecting the membrane to the cytoskeleton.
Takenawa, T., & Suetsugu, S. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2069 · Cited by 947
Stress fibers are generated by two distinct actin assembly mechanisms in motile cells
Hotulainen, P., & Lappalainen, P. (2006) · The Journal of Cell Biology · doi:10.1083/jcb.200511093 · Cited by 934
The lamellipodium: where motility begins
Small, J. V., Stradal, T., Vignal, E., & Rottner, K. (2002) · Trends in Cell Biology · doi:10.1016/s0962-8924(01)02237-1 · Cited by 922
Cooperation between mDia1 and ROCK in Rho-induced actin reorganization
Watanabe, N., Kato, T., Fujita, A., Ishizaki, T., & Narumiya, S. (1999) · Nature Cell Biology · doi:10.1038/11056 · Cited by 898
Adhesion-Dependent Cell Mechanosensitivity
Bershadsky, A. D., Balaban, N. Q., & Geiger, B. (2003) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.19.111301.153011 · Cited by 874
Cytoskeletal dynamics and nerve growth
Mitchison, T., & Kirschner, M. (1988) · Neuron · doi:10.1016/0896-6273(88)90124-9 · Cited by 871
Forscher, P., & Smith, S. J. (1988) · The Journal of cell biology · doi:10.1083/jcb.107.4.1505 · Cited by 854
Antagonism between Ena/VASP Proteins and Actin Filament Capping Regulates Fibroblast Motility
Bear, J. E., Svitkina, T. M., Krause, M., Schafer, D. A., Loureiro, J. J., Strasser, G. A., Maly, I. V., Chaga, O. Y., Cooper, J. A., Borisy, G. G., et al. (2002) · Cell · doi:10.1016/s0092-8674(02)00731-6 · Cited by 847
An interaction between alpha-actinin and the beta 1 integrin subunit in vitro.
Otey, C. A., Pavalko, F. M., & Burridge, K. (1990) · The Journal of cell biology · doi:10.1083/jcb.111.2.721 · Cited by 843
Paxillin and focal adhesion signalling
Turner, C. E. (2000) · Nature Cell Biology · doi:10.1038/35046659 · Cited by 839
Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck
Eden, S., Rohatgi, R., Podtelejnikov, A. V., Mann, M., & Kirschner, M. W. (2002) · Nature · doi:10.1038/nature00859 · Cited by 835
Watanabe, N., Madaule, P., Reid, T., Ishizaki, T., Watanabe, G., Kakizuka, A., Saito, Y., Nakao, K., Jockusch, B. M., & Narumiya, S. (1997) · The EMBO Journal · doi:10.1093/emboj/16.11.3044 · Cited by 823
Mechanism and Function of Formins in the Control of Actin Assembly
Goode, B. L., & Eck, M. J. (2007) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.75.103004.142647 · Cited by 821
Two Distinct Actin Networks Drive the Protrusion of Migrating Cells
Ponti, A., Machacek, M., Gupton, S. L., Waterman-Storer, C. M., & Danuser, G. (2004) · Science · doi:10.1126/science.1100533 · Cited by 819
Actin microfilament dynamics in locomoting cells
Theriot, J. A., & Mitchison, T. J. (1991) · Nature · doi:10.1038/352126a0 · Cited by 792
Mechanism of filopodia initiation by reorganization of a dendritic network
Svitkina, T. M., Bulanova, E. A., Chaga, O. Y., Vignjevic, D. M., Kojima, S.-I., Vasiliev, J. M., & Borisy, G. G. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200210174 · Cited by 770
Role of Formins in Actin Assembly: Nucleation and Barbed-End Association
Pruyne, D., Evangelista, M., Yang, C., Bi, E., Zigmond, S., Bretscher, A., & Boone, C. (2002) · Science · doi:10.1126/science.1072309 · Cited by 764
Cofilin Changes the Twist of F-Actin: Implications for Actin Filament Dynamics and Cellular Function
McGough, A., Pope, B., Chiu, W., & Weeds, A. (1997) · The Journal of Cell Biology · doi:10.1083/jcb.138.4.771 · Cited by 761
Adhesion assembly, disassembly and turnover in migrating cells – over and over and over again
Webb, D. J., Parsons, J. T., & Horwitz, A. F. (2002) · Nature Cell Biology · doi:10.1038/ncb0402-e97 · Cited by 757
Autoinhibition and activation mechanisms of the Wiskott–Aldrich syndrome protein
Kim, A. S., Kakalis, L. T., Abdul-Manan, N., Liu, G. A., & Rosen, M. K. (2000) · Nature · doi:10.1038/35004513 · Cited by 751
Svitkina, T. M., Verkhovsky, A. B., McQuade, K. M., & Borisy, G. G. (1997) · The Journal of Cell Biology · doi:10.1083/jcb.139.2.397 · Cited by 718
WAVE, a novel WASP-family protein involved in actin reorganization induced by Rac
Miki, H., Suetsugu, S., & Takenawa, T. (1998) · The EMBO Journal · doi:10.1093/emboj/17.23.6932 · Cited by 709
Andrianantoandro, E., & Pollard, T. D. (2006) · Molecular Cell · doi:10.1016/j.molcel.2006.08.006 · Cited by 707
Mechanism of Actin-Based Motility
Pantaloni, D., Clainche, C. L., & Carlier, M.-F. (2001) · Science · doi:10.1126/science.1059975 · Cited by 700
Self-citationNiwa, R., Nagata-Ohashi, K., Takeichi, M., Mizuno, K., & Uemura, T. (2002) · Cell · doi:10.1016/s0092-8674(01)00638-9 · Cited by 693
Early molecular events in the assembly of matrix adhesions at the leading edge of migrating cells
Zaidel-Bar, R., Ballestrem, C., Kam, Z., & Geiger, B. (2003) · Journal of Cell Science · doi:10.1242/jcs.00792 · Cited by 674
Higgs, H. N., & Pollard, T. D. (2001) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.70.1.649 · Cited by 673
Bni1p, a Yeast Formin Linking Cdc42p and the Actin Cytoskeleton During Polarized Morphogenesis
Evangelista, M., Blundell, K., Longtine, M. S., Chow, C. J., Adames, N., Pringle, J. R., Peter, M., & Boone, C. (1997) · Science · doi:10.1126/science.276.5309.118 · Cited by 647
Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP
Miki, H., Sasaki, T., Takai, Y., & Takenawa, T. (1998) · Nature · doi:10.1038/34208 · Cited by 643
Mechanism of N-Wasp Activation by Cdc42 and Phosphatidylinositol 4,5-Bisphosphate
Rohatgi, R., Ho, H.-Y. H., & Kirschner, M. W. (2000) · The Journal of Cell Biology · doi:10.1083/jcb.150.6.1299 · Cited by 643
The matrix corroded: podosomes and invadopodia in extracellular matrix degradation
Linder, S. (2007) · Trends in Cell Biology · doi:10.1016/j.tcb.2007.01.002 · Cited by 640
Exchange of actin subunits at the leading edge of living fibroblasts: possible role of treadmilling.
Wang, Y. L. (1985) · The Journal of cell biology · doi:10.1083/jcb.101.2.597 · Cited by 635
Interplay between Rac and Rho in the control of substrate contact dynamics
Rottner, K., Hall, A., & Small, J. V. (1999) · Current Biology · doi:10.1016/s0960-9822(99)80286-3 · Cited by 625
α-Actinin: Immunofluorescent localization of a muscle structural protein in nonmuscle cells
Lazarides, E., & Burridge, K. (1975) · Cell · doi:10.1016/0092-8674(75)90180-4 · Cited by 609
Brown, M. C., & Turner, C. E. (2004) · Physiological Reviews · doi:10.1152/physrev.00002.2004 · Cited by 609
Actin polymerization is induced by Arp 2/3 protein complex at the surface of Listeria monocytogenes
Welch, M. D., Iwamatsu, A., & Mitchison, T. J. (1997) · Nature · doi:10.1038/385265a0 · Cited by 598
Cortactin promotes and stabilizes Arp2/3-induced actin filament network formation
Weaver, A. M., Karginov, A. V., Kinley, A. W., Weed, S. A., Li, Y., Parsons, J. T., & Cooper, J. A. (2001) · Current Biology · doi:10.1016/s0960-9822(01)00098-7 · Cited by 597
Foot and mouth: podosomes, invadopodia and circular dorsal ruffles
Buccione, R., Orth, J. D., & McNiven, M. A. (2004) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1436 · Cited by 594
Blanchoin, L., Amann, K. J., Higgs, H. N., Marchand, J.-B., Kaiser, D. A., & Pollard, T. D. (2000) · Nature · doi:10.1038/35010008 · Cited by 586
Molecular interactions in cell adhesion complexes
Yamada, K. (1997) · Current Opinion in Cell Biology · doi:10.1016/s0955-0674(97)80155-x · Cited by 584
Dynamics and segregation of cell–matrix adhesions in cultured fibroblasts
Zamir, E., Katz, M., Posen, Y., Erez, N., Yamada, K. M., Katz, B.-Z., Lin, S., Lin, D. C., Bershadsky, A., Kam, Z., et al. (2000) · Nature Cell Biology · doi:10.1038/35008607 · Cited by 582
Activation of Arp2/3 complex-mediated actin polymerization by cortactin
Uruno, T., Liu, J., Zhang, P., Fan, Y.-X., Egile, C., Li, R., Mueller, S. C., & Zhan, X. (2001) · Nature Cell Biology · doi:10.1038/35060051 · Cited by 568 · cited 1×
“The acidic domain and the tandem repeats are sufficient to stimulate the Arp2/3 complex (230, 243).”
BackgroundRomero, S., Le Clainche, C., Didry, D., Egile, C., Pantaloni, D., & Carlier, M.-F. (2004) · Cell · doi:10.1016/j.cell.2004.09.039 · Cited by 565
Self-citationControl of the Assembly of ATP- and ADP-Actin by Formins and Profilin
Kovar, D. R., Harris, E. S., Mahaffy, R., Higgs, H. N., & Pollard, T. D. (2006) · Cell · doi:10.1016/j.cell.2005.11.038 · Cited by 562
IRSp53 is an essential intermediate between Rac and WAVE in the regulation of membrane ruffling
Miki, H., Yamaguchi, H., Suetsugu, S., & Takenawa, T. (2000) · Nature · doi:10.1038/35047107 · Cited by 557
How profilin promotes actin filament assembly in the presence of thymosin β4
Pantaloni, D., & Carlier, M.-F. (1993) · Cell · doi:10.1016/0092-8674(93)90544-z · Cited by 543
Self-citationCrystal Structure of Arp2/3 Complex
Robinson, R. C., Turbedsky, K., Kaiser, D. A., Marchand, J.-B., Higgs, H. N., Choe, S., & Pollard, T. D. (2001) · Science · doi:10.1126/science.1066333 · Cited by 540
Fujiwara, K., & Pollard, T. D. (1976) · The Journal of cell biology · doi:10.1083/jcb.71.3.848 · Cited by 534
Hierarchical assembly of cell–matrix adhesion complexes
Zaidel-Bar, R., Cohen, M., Addadi, L., & Geiger, B. (2004) · Biochemical Society Transactions · doi:10.1042/bst0320416 · Cited by 523
Integration of Multiple Signals Through Cooperative Regulation of the N-WASP-Arp2/3 Complex
Prehoda, K. E., Scott, J. A., Mullins, R. D., & Lim, W. A. (2000) · Science · doi:10.1126/science.290.5492.801 · Cited by 522
Egile, C., Loisel, T. P., Laurent, V., Li, R., Pantaloni, D., Sansonetti, P. J., & Carlier, M.-F. (1999) · The Journal of Cell Biology · doi:10.1083/jcb.146.6.1319 · Cited by 522
Self-citationRegulation of vinculin binding to talin and actin by phosphatidyl-inositol-4-5-bisphosphate
Gilmore, A. P., & Burridge, K. (1996) · Nature · doi:10.1038/381531a0 · Cited by 521
Differential Transmission of Actin Motion Within Focal Adhesions
Hu, K., Ji, L., Applegate, K. T., Danuser, G., & Waterman-Storer, C. M. (2007) · Science · doi:10.1126/science.1135085 · Cited by 512
Welch, M. D., Rosenblatt, J., Skoble, J., Portnoy, D. A., & Mitchison, T. J. (1998) · Science · doi:10.1126/science.281.5373.105 · Cited by 508
Machesky, L. M., Atkinson, S. J., Ampe, C., Vandekerckhove, J., & Pollard, T. D. (1994) · The Journal of cell biology · doi:10.1083/jcb.127.1.107 · Cited by 507
The structure and regulation of vinculin
Ziegler, W. H., Liddington, R. C., & Critchley, D. R. (2006) · Trends in Cell Biology · doi:10.1016/j.tcb.2006.07.004 · Cited by 481
Microtubule Targeting of Substrate Contacts Promotes Their Relaxation and Dissociation
Kaverina, I., Krylyshkina, O., & Small, J. V. (1999) · The Journal of Cell Biology · doi:10.1083/jcb.146.5.1033 · Cited by 480
Two-piconewton slip bond between fibronectin and the cytoskeleton depends on talin
Jiang, G., Giannone, G., Critchley, D. R., Fukumoto, E., & Sheetz, M. P. (2003) · Nature · doi:10.1038/nature01805 · Cited by 455
Laukaitis, C. M., Webb, D. J., Donais, K., & Horwitz, A. F. (2001) · The Journal of Cell Biology · doi:10.1083/jcb.153.7.1427 · Cited by 455
Kovar, D. R., & Pollard, T. D. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0405902101 · Cited by 436
Toca-1 Mediates Cdc42-Dependent Actin Nucleation by Activating the N-WASP-WIP Complex
Ho, H.-Y. H., Rohatgi, R., Lebensohn, A. M., Ma, L., Li, J., Gygi, S. P., & Kirschner, M. W. (2004) · Cell · doi:10.1016/j.cell.2004.06.027 · Cited by 434
The Mouse Formin mDia1 Is a Potent Actin Nucleation Factor Regulated by Autoinhibition
Li, F., & Higgs, H. N. (2003) · Current Biology · doi:10.1016/s0960-9822(03)00540-2 · Cited by 432
Hemostatic, inflammatory, and fibroblast responses are blunted in mice lacking gelsolin
Witke, W., Sharpe, A. H., Hartwig, J. H., Azuma, T., Stossel, T. P., & Kwiatkowski, D. J. (1995) · Cell · doi:10.1016/0092-8674(95)90369-0 · Cited by 431
α‐actinin revisited: A fresh look at an old player
Otey, C. A., & Carpen, O. (2004) · Cell Motility · doi:10.1002/cm.20007 · Cited by 429
Schafer, D. A., Jennings, P. B., & Cooper, J. A. (1996) · The Journal of cell biology · doi:10.1083/jcb.135.1.169 · Cited by 427
Recruitment of the Arp2/3 complex to vinculin
DeMali, K. A., Barlow, C. A., & Burridge, K. (2002) · The Journal of Cell Biology · doi:10.1083/jcb.200206043 · Cited by 425
Cdc42 induces filopodia by promoting the formation of an IRSp53:Mena complex
Krugmann, S., Jordens, I., Gevaert, K., Driessens, M., Vandekerckhove, J., & Hall, A. (2001) · Current Biology · doi:10.1016/s0960-9822(01)00506-1 · Cited by 420
Lamellipodial Versus Filopodial Mode of the Actin Nanomachinery
Mejillano, M. R., Kojima, S.-I., Applewhite, D. A., Gertler, F. B., Svitkina, T. M., & Borisy, G. G. (2004) · Cell · doi:10.1016/j.cell.2004.07.019 · Cited by 420
Weed, S. A., Karginov, A. V., Schafer, D. A., Weaver, A. M., Kinley, A. W., Cooper, J. A., & Parsons, J. T. (2000) · The Journal of Cell Biology · doi:10.1083/jcb.151.1.29 · Cited by 419
Gelsolin superfamily proteins: key regulators of cellular functions
Silacci, P., Mazzolai, L., Gauci, C., Stergiopulos, N., Yin, H. L., & Hayoz, D. (2004) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-004-4225-6 · Cited by 416
Abi1 is essential for the formation and activation of a WAVE2 signalling complex
Innocenti, M., Zucconi, A., Disanza, A., Frittoli, E., Areces, L. B., Steffen, A., Stradal, T. E. B., Fiore, P. P. D., Carlier, M.-F., & Scita, G. (2004) · Nature Cell Biology · doi:10.1038/ncb1105 · Cited by 410
Self-citationYeast formins regulate cell polarity by controlling the assembly of actin cables
Sagot, I., Klee, S. K., & Pellman, D. (2002) · Nature Cell Biology · doi:10.1038/ncb719 · Cited by 408
Regulated Actin Cytoskeleton Assembly at Filopodium Tips Controls Their Extension and Retraction
Mallavarapu, A., & Mitchison, T. (1999) · The Journal of Cell Biology · doi:10.1083/jcb.146.5.1097 · Cited by 406
Molecular requirements for actin-based lamella formation in Drosophila S2 cells
Rogers, S. L., Wiedemann, U., Stuurman, N., & Vale, R. D. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200303023 · Cited by 401
Sra‐1 and Nap1 link Rac to actin assembly driving lamellipodia formation
Steffen, A., Rottner, K., Ehinger, J., Innocenti, M., Scita, G., Wehland, J., & Stradal, T. E. (2004) · The EMBO Journal · doi:10.1038/sj.emboj.7600084 · Cited by 396
Mattila, P. K., Pykäläinen, A., Saarikangas, J., Paavilainen, V. O., Vihinen, H., Jokitalo, E., & Lappalainen, P. (2007) · The Journal of Cell Biology · doi:10.1083/jcb.200609176 · Cited by 386
Structural basis for vinculin activation at sites of cell adhesion
Bakolitsa, C., Cohen, D. M., Bankston, L. A., Bobkov, A. A., Cadwell, G. W., Jennings, L., Critchley, D. R., Craig, S. W., & Liddington, R. C. (2004) · Nature · doi:10.1038/nature02610 · Cited by 383
Crystal Structures of a Formin Homology-2 Domain Reveal a Tethered Dimer Architecture
Xu, Y., Moseley, J. B., Sagot, I., Poy, F., Pellman, D., Goode, B. L., & Eck, M. J. (2004) · Cell · doi:10.1016/s0092-8674(04)00210-7 · Cited by 382
Reinhard, M., Halbrügge, M., Scheer, U., Wiegand, C., Jockusch, B. M., & Walter, U. (1992) · The EMBO Journal · doi:10.1002/j.1460-2075.1992.tb05264.x · Cited by 381
F-actin binding site masked by the intramolecular association of vinculin head and tail domains
Johnson, R. P., & Craig, S. W. (1995) · Nature · doi:10.1038/373261a0 · Cited by 380
Diaphanous-Related Formins Bridge Rho GTPase and Src Tyrosine Kinase Signaling
Tominaga, T., Sahai, E., Chardin, P., McCormick, F., Courtneidge, S. A., & Alberts, A. S. (2000) · Molecular Cell · doi:10.1016/s1097-2765(00)80399-8 · Cited by 379
Involvement of microtubules in the control of adhesion-dependent signal transduction
Bershadsky, A., Chausovsky, A., Becker, E., Lyubimova, A., & Geiger, B. (1996) · Current Biology · doi:10.1016/s0960-9822(02)70714-8 · Cited by 378
Focal adhesion and actin dynamics: a place where kinases and proteases meet to promote invasion
Carragher, N. O., & Frame, M. C. (2004) · Trends in Cell Biology · doi:10.1016/j.tcb.2004.03.011 · Cited by 373
Ramesh, N., Antón, I. M., Hartwig, J. H., & Geha, R. S. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.26.14671 · Cited by 373
Drosophila Spire is an actin nucleation factor
Quinlan, M. E., Heuser, J. E., Kerkhoff, E., & Dyche Mullins, R. (2005) · Nature · doi:10.1038/nature03241 · Cited by 371
Structural basis of actin filament nucleation and processive capping by a formin homology 2 domain
Otomo, T., Tomchick, D. R., Otomo, C., Panchal, S. C., Machius, M., & Rosen, M. K. (2005) · Nature · doi:10.1038/nature03251 · Cited by 370
Role of Proteins of the Ena/VASP Family in Actin-based Motility of Listeria monocytogenes
Laurent, V., Loisel, T. P., Harbeck, B., Wehman, A., Gröbe, L., Jockusch, B. M., Wehland, J., Gertler, F. B., & Carlier, M.-F. (1999) · The Journal of Cell Biology · doi:10.1083/jcb.144.6.1245 · Cited by 362
Self-citationSuter, D. M., & Forscher, P. (2000) · Journal of Neurobiology · doi:10.1002/1097-4695(200008)44:2<97::aid-neu2>3.0.co;2-u · Cited by 354
Control of actin dynamics in cell motility
Carlier, M.-F., & Pantaloni, D. (1997) · Journal of Molecular Biology · doi:10.1006/jmbi.1997.1062 · Cited by 351
Self-citationRohatgi, R., Nollau, P., Ho, H.-Y. H., Kirschner, M. W., & Mayer, B. J. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m103856200 · Cited by 350
Kovar, D. R., Kuhn, J. R., Tichy, A. L., & Pollard, T. D. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200211078 · Cited by 337
Snapper, S. B., Takeshima, F., Antón, I., Liu, C.-H., Thomas, S. M., Nguyen, D., Dudley, D., Fraser, H., Purich, D., Lopez-Ilasaca, M., et al. (2001) · Nature Cell Biology · doi:10.1038/ncb1001-897 · Cited by 332
VASP dynamics during lamellipodia protrusion
Rottner, K., Behrendt, B., Small, J. V., & Wehland, J. (1999) · Nature Cell Biology · doi:10.1038/13040 · Cited by 331
Alberts, A. S. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m006205200 · Cited by 329
Faix, J., & Rottner, K. (2006) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2005.11.002 · Cited by 326
Martel, V., Racaud-Sultan, C., Dupe, S., Marie, C., Paulhe, F., Galmiche, A., Block, M. R., & Albiges-Rizo, C. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m102373200 · Cited by 318
Cramer, L. P., Siebert, M., & Mitchison, T. J. (1997) · The Journal of Cell Biology · doi:10.1083/jcb.136.6.1287 · Cited by 316
Suetsugu, S., Yamazaki, D., Kurisu, S., & Takenawa, T. (2003) · Developmental Cell · doi:10.1016/s1534-5807(03)00297-1 · Cited by 314
Lewis, A. K., & Bridgman, P. C. (1992) · The Journal of cell biology · doi:10.1083/jcb.119.5.1219 · Cited by 309
IQGAP1 in cellular signaling: bridging the GAP
Brown, M. D., & Sacks, D. B. (2006) · Trends in Cell Biology · doi:10.1016/j.tcb.2006.03.002 · Cited by 295
Martinez-Quiles, N., Ho, H.-Y. H., Kirschner, M. W., Ramesh, N., & Geha, R. S. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.24.12.5269-5280.2004 · Cited by 292
The Rho Family GTPase Rif Induces Filopodia through mDia2
Pellegrin, S., & Mellor, H. (2005) · Current Biology · doi:10.1016/j.cub.2005.01.011 · Cited by 289
Blanchoin, L., Pollard, T. D., & Mullins, R. D. (2000) · Current Biology · doi:10.1016/s0960-9822(00)00749-1 · Cited by 284
WIP regulates N-WASP-mediated actin polymerization and filopodium formation
Martinez-Quiles, N., Rohatgi, R., Antón, I. M., Medina, M., Saville, S. P., Miki, H., Yamaguchi, H., Takenawa, T., Hartwig, J. H., Geha, R. S., et al. (2001) · Nature Cell Biology · doi:10.1038/35074551 · Cited by 282
Giannone, G., Jiang, G., Sutton, D. H., Critchley, D. R., & Sheetz, M. P. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200302001 · Cited by 276
Tumor cells caught in the act of invading: their strategy for enhanced cell motility
Wang, W., Goswami, S., Sahai, E., Wyckoff, J. B., Segall, J. E., & Condeelis, J. S. (2005) · Trends in Cell Biology · doi:10.1016/j.tcb.2005.01.003 · Cited by 274
Formin Leaky Cap Allows Elongation in the Presence of Tight Capping Proteins
Zigmond, S. H., Evangelista, M., Boone, C., Yang, C., Dar, A. C., Sicheri, F., Forkey, J., & Pring, M. (2003) · Current Biology · doi:10.1016/j.cub.2003.09.057 · Cited by 273
Substrate rigidity and force define form through tyrosine phosphatase and kinase pathways
Giannone, G., & Sheetz, M. P. (2006) · Trends in Cell Biology · doi:10.1016/j.tcb.2006.02.005 · Cited by 271
Structural and mechanistic insights into the interaction between Rho and mammalian Dia
Rose, R., Weyand, M., Lammers, M., Ishizaki, T., Ahmadian, M. R., & Wittinghofer, A. (2005) · Nature · doi:10.1038/nature03604 · Cited by 269
Sasahara, Y., Rachid, R., Byrne, M. J., de la Fuente, M. A., Abraham, R. T., Ramesh, N., & Geha, R. S. (2002) · Molecular Cell · doi:10.1016/s1097-2765(02)00728-1 · Cited by 269
The Diaphanous-related formin dDia2 is required for the formation and maintenance of filopodia
Schirenbeck, A., Bretschneider, T., Arasada, R., Schleicher, M., & Faix, J. (2005) · Nature Cell Biology · doi:10.1038/ncb1266 · Cited by 267
Interaction of Cortactin and N-WASp with Arp2/3 Complex
Weaver, A. M., Heuser, J. E., Karginov, A. V., Lee, W.-L., Parsons, J. T., & Cooper, J. A. (2002) · Current Biology · doi:10.1016/s0960-9822(02)01035-7 · Cited by 267
Cell migration without a lamellipodium
Gupton, S. L., Anderson, K. L., Kole, T. P., Fischer, R. S., Ponti, A., Hitchcock-DeGregori, S. E., Danuser, G., Fowler, V. M., Wirtz, D., Hanein, D., et al. (2005) · The Journal of Cell Biology · doi:10.1083/jcb.200406063 · Cited by 266
Talin Is Essential for Integrin Function in Drosophila
Brown, N. H., Gregory, S. L., Rickoll, W. L., Fessler, L. I., Prout, M., White, R. A. H., & Fristrom, J. W. (2002) · Developmental Cell · doi:10.1016/s1534-5807(02)00290-3 · Cited by 264
Peng, J., Wallar, B. J., Flanders, A., Swiatek, P. J., & Alberts, A. S. (2003) · Current Biology · doi:10.1016/s0960-9822(03)00170-2 · Cited by 263
Protein complexes regulating Arp2/3-mediated actin assembly
Stradal, T. E., & Scita, G. (2006) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2005.12.003 · Cited by 261
Assembling an actin cytoskeleton for cell attachment and movement
Small, J. V., Rottner, K., Kaverina, I., & Anderson, K. I. (1998) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/s0167-4889(98)00080-9 · Cited by 261
Talin contains three actin-binding sites each of which is adjacent to a vinculin-binding site
Hemmings, L., Rees, D. J. G., Ohanian, V., Bolton, S. J., Gilmore, A. P., Patel, B., Priddle, H., Trevithick, J. E., Hynes, R. O., & Critchley, D. R. (1996) · Journal of Cell Science · doi:10.1242/jcs.109.11.2715 · Cited by 260
Mechanism of Formin-Induced Nucleation of Actin Filaments
Pring, M., Evangelista, M., Boone, C. M., Yang, C., & Zigmond, S. H. (2002) · Biochemistry · doi:10.1021/bi026520j · Cited by 260
Lommel, S., Benesch, S., Rottner, K., Franz, T., Wehland, J., & Kühn, R. (2001) · EMBO reports · doi:10.1093/embo-reports/kve197 · Cited by 259
An interaction between zyxin and alpha-actinin.
Crawford, A. W., Michelsen, J. W., & Beckerle, M. C. (1992) · The Journal of cell biology · doi:10.1083/jcb.116.6.1381 · Cited by 256
Sun, Y., Martin, A. C., & Drubin, D. G. (2006) · Developmental Cell · doi:10.1016/j.devcel.2006.05.008 · Cited by 255
Molecular details of formin-mediated actin assembly
Kovar, D. R. (2006) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2005.12.011 · Cited by 251
The Arp2/3 complex branches filament barbed ends: functional antagonism with capping proteins
Pantaloni, D., Boujemaa, R., Didry, D., Gounon, P., & Carlier, M.-F. (2000) · Nature Cell Biology · doi:10.1038/35017011 · Cited by 250
Self-citationDisanza, A., Mantoani, S., Hertzog, M., Gerboth, S., Frittoli, E., Steffen, A., Berhoerster, K., Kreienkamp, H.-J., Milanesi, F., Fiore, P. P. D., et al. (2006) · Nature Cell Biology · doi:10.1038/ncb1502 · Cited by 249
Vinculin activation by talin through helical bundle conversion
Izard, T., Evans, G., Borgon, R. A., Rush, C. L., Bricogne, G., & Bois, P. R. J. (2004) · Nature · doi:10.1038/nature02281 · Cited by 246
Formation of filopodia-like bundles in vitro from a dendritic network
Vignjevic, D., Yarar, D., Welch, M. D., Peloquin, J., Svitkina, T., & Borisy, G. G. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200208059 · Cited by 246
Filopodia Formation in the Absence of Functional WAVE- and Arp2/3-Complexes
Steffen, A., Faix, J., Resch, G. P., Linkner, J., Wehland, J., Small, J. V., Rottner, K., & Stradal, T. E. B. (2006) · Molecular Biology of the Cell · doi:10.1091/mbc.e05-11-1088 · Cited by 244
Characterization of actin filament severing by actophorin from Acanthamoeba castellanii.
Maciver, S. K., Zot, H. G., & Pollard, T. D. (1991) · The Journal of cell biology · doi:10.1083/jcb.115.6.1611 · Cited by 242
The Arp2/3 complex nucleates actin filament branches from the sides of pre-existing filaments
Amann, K. J., & Pollard, T. D. (2001) · Nature Cell Biology · doi:10.1038/35060104 · Cited by 240
WAVE2 is required for directed cell migration and cardiovascular development
Yamazaki, D., Suetsugu, S., Miki, H., Kataoka, Y., Nishikawa, S.-I., Fujiwara, T., Yoshida, N., & Takenawa, T. (2003) · Nature · doi:10.1038/nature01770 · Cited by 240
Src phosphorylation of cortactin enhances actin assembly
Tehrani, S., Tomasevic, N., Weed, S., Sakowicz, R., & Cooper, J. A. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0701077104 · Cited by 239
Purification and architecture of the ubiquitous Wave complex
Gautreau, A., Ho, H.-Y. H., Li, J., Steen, H., Gygi, S. P., & Kirschner, M. W. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0400628101 · Cited by 236
Abi1 regulates the activity of N-WASP and WAVE in distinct actin-based processes
Innocenti, M., Gerboth, S., Rottner, K., Lai, F. P. L., Hertzog, M., Stradal, T. E. B., Frittoli, E., Didry, D., Polo, S., Disanza, A., et al. (2005) · Nature Cell Biology · doi:10.1038/ncb1304 · Cited by 231
Self-citationSuppression of tumorigenicity in transformed cells after transfection with vinculin cDNA.
Rodríguez Fernández, J. L., Geiger, B., Salomon, D., Sabanay, I., Zöller, M., & Ben-Ze'ev, A. (1992) · The Journal of cell biology · doi:10.1083/jcb.119.2.427 · Cited by 225
Didry, D., Carlier, M., & Pantaloni, D. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.40.25602 · Cited by 224
Self-citationDisruption of thetalin gene arrests mouse development at the gastrulation stage
Monkley, S. J., Zhou, X.-H., Kinston, S., Giblett, S. M., Hemmings, L., Priddle, H., Brown, J., Pritchard, C. A., Critchley, D. R., & F�ssler, R. (2000) · Developmental Dynamics · doi:10.1002/1097-0177(2000)9999:9999<::aid-dvdy1079>3.0.co;2-y · Cited by 221
An intramolecular association between the head and tail domains of vinculin modulates talin binding.
Johnson, R. P., & Craig, S. W. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)99920-5 · Cited by 218
Van Nhieu, G. T. (1997) · The EMBO Journal · doi:10.1093/emboj/16.10.2717 · Cited by 218
Cell migration during gastrulation
Keller, R. (2005) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2005.08.006 · Cited by 212
Hertzog, M., van Heijenoort, C., Didry, D., Gaudier, M., Coutant, J., Gigant, B., Didelot, G., Préat, T., Knossow, M., Guittet, E., et al. (2004) · Cell · doi:10.1016/s0092-8674(04)00403-9 · Cited by 212
Self-citationEps8 controls actin-based motility by capping the barbed ends of actin filaments
Disanza, A., Carlier, M.-F., Stradal, T. E. B., Didry, D., Frittoli, E., Confalonieri, S., Croce, A., Wehland, J., Di Fiore, P. P., & Scita, G. (2004) · Nature Cell Biology · doi:10.1038/ncb1199 · Cited by 212
Self-citationCarlier, M.-F., Nioche, P., Broutin-L'Hermite, I., Boujemaa, R., Le Clainche, C., Egile, C., Garbay, C., Ducruix, A., Sansonetti, P., & Pantaloni, D. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m000687200 · Cited by 211
Self-citationGingras, A. R., Ziegler, W. H., Frank, R., Barsukov, I. L., Roberts, G. C. K., Critchley, D. R., & Emsley, J. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m508060200 · Cited by 210
Syndapins integrate N-WASP in receptor-mediated endocytosis
Kessels, M. M., & Qualmann, B. (2002) · The EMBO Journal · doi:10.1093/emboj/cdf604 · Cited by 209
Control of Actin Dynamics in Cell Motility
Carlier, M.-F., Ressad, F., & Pantaloni, D. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.48.33827 · Cited by 206
Self-citationSpatial and Temporal Relationships between Actin-Filament Nucleation, Capping, and Disassembly
Iwasa, J. H., & Mullins, R. D. (2007) · Current Biology · doi:10.1016/j.cub.2007.02.012 · Cited by 204
Cytoskeletal proteins talin and vinculin in integrin-mediated adhesion
Critchley, D. R. (2004) · Biochemical Society Transactions · doi:10.1042/bst0320831 · Cited by 204
Nikolopoulos, S. N., & Turner, C. E. (2000) · The Journal of Cell Biology · doi:10.1083/jcb.151.7.1435 · Cited by 199
Caldesmon Inhibits Nonmuscle Cell Contractility and Interferes with the Formation of Focal Adhesions
Helfman, D. M., Levy, E. T., Berthier, C., Shtutman, M., Riveline, D., Grosheva, I., Lachish-Zalait, A., Elbaum, M., & Bershadsky, A. D. (1999) · Molecular Biology of the Cell · doi:10.1091/mbc.10.10.3097 · Cited by 197
Kelleher, J. F., Atkinson, S. J., & Pollard, T. D. (1995) · The Journal of cell biology · doi:10.1083/jcb.131.2.385 · Cited by 195
Model of Formin-Associated Actin Filament Elongation
Vavylonis, D., Kovar, D. R., O'Shaughnessy, B., & Pollard, T. D. (2006) · Molecular Cell · doi:10.1016/j.molcel.2006.01.016 · Cited by 194
Dynamin2 and Cortactin Regulate Actin Assembly and Filament Organization
Schafer, D. A., Weed, S. A., Binns, D., Karginov, A. V., Parsons, J. T., & Cooper, J. A. (2002) · Current Biology · doi:10.1016/s0960-9822(02)01228-9 · Cited by 191
Spatial regulation of actin dynamics: a tropomyosin-free, actin-rich compartment at the leading edge
DesMarais, V., Ichetovkin, I., Condeelis, J., & Hitchcock-DeGregori, S. E. (2002) · Journal of Cell Science · doi:10.1242/jcs.00147 · Cited by 189
Dissecting the link between stress fibres and focal adhesions by CALI with EGFP fusion proteins
Rajfur, Z., Roy, P., Otey, C., Romer, L., & Jacobson, K. (2002) · Nature Cell Biology · doi:10.1038/ncb772 · Cited by 188
Cortactin: The Gray Eminence of the Cytoskeleton
Cosen-Binker, L. I., & Kapus, A. (2006) · Physiology · doi:10.1152/physiol.00012.2006 · Cited by 187
The comings and goings of actin: coupling protrusion and retraction in cell motility
Small, J. V., & Resch, G. P. (2005) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2005.08.004 · Cited by 186
Imaging Sites of N-WASP Activity in Lamellipodia and Invadopodia of Carcinoma Cells
Lorenz, M., Yamaguchi, H., Wang, Y., Singer, R. H., & Condeelis, J. (2004) · Current Biology · doi:10.1016/j.cub.2004.04.008 · Cited by 186
WAVE2 deficiency reveals distinct roles in embryogenesis and Rac‐mediated actin‐based motility
Yan, C., Martinez‐Quiles, N., Eden, S., Shibata, T., Takeshima, F., Shinkura, R., Fujiwara, Y., Bronson, R., Snapper, S. B., Kirschner, M. W., et al. (2003) · The EMBO Journal · doi:10.1093/emboj/cdg350 · Cited by 186
The regulation of mDia1 by autoinhibition and its release by Rho•GTP
Lammers, M., Rose, R., Scrima, A., & Wittinghofer, A. (2005) · The EMBO Journal · doi:10.1038/sj.emboj.7600879 · Cited by 182
Cortactin Interacts with WIP in Regulating Arp2/3 Activation and Membrane Protrusion
Kinley, A. W., Weed, S. A., Weaver, A. M., Karginov, A. V., Bissonette, E., Cooper, J. A., & Parsons, J. T. (2003) · Current Biology · doi:10.1016/s0960-9822(03)00107-6 · Cited by 181
Mechanism of Actin Network Attachment to Moving Membranes: Barbed End Capture by N-WASP WH2 Domains
Co, C., Wong, D. T., Gierke, S., Chang, V., & Taunton, J. (2007) · Cell · doi:10.1016/j.cell.2006.12.049 · Cited by 179
Lo, S. H. (2004) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/s1357-2725(03)00171-7 · Cited by 179
Priddle, H., Hemmings, L., Monkley, S., Woods, A., Patel, B., Sutton, D., Dunn, G. A., Zicha, D., & Critchley, D. R. (1998) · The Journal of Cell Biology · doi:10.1083/jcb.142.4.1121 · Cited by 177
Contingent Phosphorylation/Dephosphorylation Provides a Mechanism of Molecular Memory in WASP
Torres, E., & Rosen, M. K. (2003) · Molecular Cell · doi:10.1016/s1097-2765(03)00139-4 · Cited by 173
Antón, I. M., de la Fuente, M. A., Sims, T. N., Freeman, S., Ramesh, N., Hartwig, J. H., Dustin, M. L., & Geha, R. S. (2002) · Immunity · doi:10.1016/s1074-7613(02)00268-6 · Cited by 169
An emerging link between cytoskeletal dynamics and cell adhesion molecules in growth cone guidance
Suter, D. M., & Forscher, P. (1998) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(98)80014-7 · Cited by 168
Talin: an emerging focal point of adhesion dynamics
Nayal, A., Webb, D. J., & Horwitz, A. F. (2004) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2003.11.007 · Cited by 168
Gournier, H., Goley, E. D., Niederstrasser, H., Trinh, T., & Welch, M. D. (2001) · Molecular Cell · doi:10.1016/s1097-2765(01)00393-8 · Cited by 167
Probing the integrin-actin linkage using high-resolution protein velocity mapping
Brown, C. M., Hebert, B., Kolin, D. L., Zareno, J., Whitmore, L., Horwitz, A. R., & Wiseman, P. W. (2006) · Journal of Cell Science · doi:10.1242/jcs.03321 · Cited by 167
Cytoskeletal reorganization underlying growth cone motility
Lin, C.-H., Thompson, C. A., & Forscher, P. (1994) · Current Opinion in Neurobiology · doi:10.1016/0959-4388(94)90004-3 · Cited by 166
Cory, G. O. C., Cramer, R., Blanchoin, L., & Ridley, A. J. (2003) · Molecular Cell · doi:10.1016/s1097-2765(03)00172-2 · Cited by 161
Cohen, D. M., Kutscher, B., Chen, H., Murphy, D. B., & Craig, S. W. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m600738200 · Cited by 160
The bundling activity of vasodilator-stimulated phosphoprotein is required for filopodium formation
Schirenbeck, A., Arasada, R., Bretschneider, T., Stradal, T. E. B., Schleicher, M., & Faix, J. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0511243103 · Cited by 160
Binding of the Shigella protein IpaA to vinculin induces F-actin depolymerization
Bourdet-Sicard, R. (1999) · The EMBO Journal · doi:10.1093/emboj/18.21.5853 · Cited by 159
Shimada, A., Nyitrai, M., Vetter, I. R., Kühlmann, D., Bugyi, B., Narumiya, S., Geeves, M. A., & Wittinghofer, A. (2004) · Molecular Cell · doi:10.1016/s1097-2765(04)00059-0 · Cited by 159
IQGAP1 Stimulates Actin Assembly through the N-Wasp-Arp2/3 Pathway
Clainche, C. L., Schlaepfer, D., Ferrari, A., Klingauf, M., Grohmanova, K., Veligodskiy, A., Didry, D., Le, D. N., Égile, C., Carlier, M., et al. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m607711200 · Cited by 157
Self-citationTensin1 and a previously undocumented family member, tensin2, positively regulate cell migration
Chen, H., Duncan, I. C., Bozorgchami, H., & Lo, S. H. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.022518699 · Cited by 156
Locascio, A., & Nieto, M. A. (2001) · Current Opinion in Genetics & Development · doi:10.1016/s0959-437x(00)00218-5 · Cited by 156
Hüttelmaier, S., Mayboroda, O. A., Harbeck, B., Jarchau, T., Jockusch, B. M., & Rüdiger, M. (1998) · Current Biology · doi:10.1016/s0960-9822(98)70199-x · Cited by 155
Coincidence of Actin Filaments and Talin Is Required to Activate Vinculin
Chen, H. A., Choudhury, D. M., & Craig, S. W. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m607324200 · Cited by 155
Zalevsky, J., Lempert, L., Kranitz, H., & Mullins, R. D. (2001) · Current Biology · doi:10.1016/s0960-9822(01)00603-0 · Cited by 152
How VASP enhances actin-based motility
Samarin, S., Romero, S., Kocks, C., Didry, D., Pantaloni, D., & Carlier, M. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200303191 · Cited by 151
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Metadata
- Authors
- Le Clainche, C., & Carlier, M.-F.
- Venue
- Physiological Reviews
- Publisher
- American Physiological Society
- Published
- 2008-04
- Volume
- 88
- Issue
- 2
- Pages
- 489-513
- ISSN
- 0031-9333 (ISSN-L)
- 1522-1210
- OpenAlex
- W2105809801
- Cited by
- 849
- References
- 255
- FWCI
- 3.65
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.