Virtual reality compared with in vivo exposure in the treatment of social anxiety disorder: A three-arm randomised controlled trial
Open accessAbstract
Background: People with social anxiety disorder (SAD) fear social interactions and may be reluctant to seek treatments involving exposure to social situations. Social exposure conducted in virtual reality (VR), embedded in individual cognitive–behavioural therapy (CBT), could be an answer. Aims: To show that conducting VR exposure in CBT for SAD is effective and is more practical for therapists than conducting exposure in vivo. Method: Participants were randomly assigned to either VR exposure ( n = 17), in vivo exposure ( n = 22) or waiting list ( n = 20). Participants in the active arms received individual CBT for 14 weekly sessions and outcome was assessed with questionnaires and a behaviour avoidance test. (Trial registration number ISRCTN99747069.) Results: Improvements were found on the primary (Liebowitz Social Anxiety Scale) and all five secondary outcome measures in both CBT groups compared with the waiting list. Conducting exposure in VR was more effective at post-treatment than in vivo on the primary outcome measure and on one secondary measure. Improvements were maintained at the 6-month follow-up. VR was significantly more practical for therapists than in vivo exposure. Conclusions: Using VR can be advantageous over standard CBT as a potential solution for treatment avoidance and as an efficient, cost-effective and practical medium of exposure.
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- Findingown data§ Results
Improvements were maintained at the 6-month follow-up.
“Improvements were maintained at the 6-month follow-up.”
Quote in the paperSubstantial claim - Findingown data§ Clinical outcome measures
Time-by-conditions interactions and contrasts revealed that cognitive-behavioural therapy with in virtuo exposure was more effective at follow-up on the Liebowitz Social Anxiety Scale-Self Reported version only.
“The time6 conditions interactions and contrasts revealed that CBT with in virtuo exposure was more effective at follow-up on the LSAS-SR only (Fig. 2).”
Quote in the paperSubstantial claim - Findingown data§ Results
Virtual reality was significantly more practical for therapists than in vivo exposure.
“VR was significantly more practical for therapists than in vivo exposure.”
Quote in the paperNot a substantial claim - Findingcitation§ Findings from previous studies and comparison with our findings
The advantage of in virtuo exposure that we found on certain measures was not observed in earlier social anxiety disorder trials.
“The superiority of in virtuo exposure that we observed on some of the measures has not been found in these previous studies on SAD 21,23,24”
Quote in the paperNot a substantial claim0 of 3 sources checked - Findingown data§ Implications
Treatment credibility was not a significant predictor.
“while treatment credibility was not a significant predictor.”
Quote in the paperNot a substantial claim
- Findingown data§ Clinical outcome measures
The difference in reliable change between both active conditions did not approach statistical significance.
“The difference between both active conditions did not approach statistical significance (w 2 (1) = 0.33, not significant).”
Quote in the paperSubstantial claim - Findingown data§ Implications
In the CBT with in virtuo exposure condition, working alliance was a strong and significant predictor of change on the LSAS-SR.
“working alliance was a strong and significant predictor of change in LSAS-SR in the CBT with in virtuo exposure condition (t = 72.52,P50.05, sr = 70.52)”
Quote in the paperNot a substantial claim - Findingnone given§ Main findings
All gains were maintained at the 6-month follow-up.
“All gains were maintained at the 6-month follow-up.”
Quote in the paperSubstantial claim - Study design and conductown data§ Recruitment and attrition
There were no statistical differences in the attrition rate between the two groups.
“There were no statistical differences in the attrition rate between the two groups (Fisher's exact test P = 0.67).”
Quote in the paperNot a substantial claim - Interpretationcitation§ Conclusions
In the case of social anxiety disorder, cognitive-behavioural therapy with in virtuo exposure could offer several advantages compared with traditional cognitive-behavioural therapy.
“In the case of SAD, CBT with in virtuo exposure could offer several advantages compared with traditional CBT. 14”
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- Premisecitation§ Conclusions
According to patients, in virtuo exposure is considered less frightening than in vivo exposure.
“In addition, according to patients, in virtuo exposure is considered less frightening than in vivo exposure. 16”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [16]
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- Study design and conductown data§ Recruitment and attrition
There were no differences between conditions regarding sociodemographic or clinical variables, including credibility and working alliance.
“There were no differences between conditions regarding sociodemographic or clinical variables (Table 1), including credibility and working alliance.”
Quote in the paperNot a substantial claim - Premisecitation§ Limitations
Emmelkamp and colleagues conducted a study in which the virtual scenarios replicated the stimuli from the in vivo exposure programme.
“Emmelkamp and his team 46 have conducted a study were the virtual scenarios were replicating the stimuli used in the in vivo exposure programme.”
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- Study design and conductnone given§ Limitations
The in vivo exposure scenarios were not an exact match for the in virtuo scenarios.
“Finally, the in vivo exposures did not exactly match the in virtuo scenarios.”
Quote in the paperSubstantial claim - Premisecitation§ Implications
Bertrand and Bouchard showed that perceived usefulness is the strongest predictor of intention to use virtual reality.
“Bertrand & Bouchard 47 have shown that the best predictor of intention to use VR is its perceived usefulness.”
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- Premisecitation§ Findings from previous studies and comparison with our findings
Kampmann and colleagues did not assess practical factors such as cost or therapist burden when using either exposure format.
“Moreover, Kampmann's team did not evaluate the practical aspects (such as costs, burden for therapists) of using both types of exposure, which is an important factor when considering treatment delivery.”
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- Premisecitation§ Limitations
CBT trials for social anxiety disorder typically do not replicate exposure tasks.
“CBT trials for SAD do not usually replicate exposure tasks (for example Stangier et al 11 )”
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- Premisecitation§ Findings from previous studies and comparison with our findings
Exposure exercises that rely only on dialogues with virtual humans create technical difficulties that may complicate exposure.
“Finally, exposure exercises based solely on dialogues with virtual humans raise technical challenges that might make exposure more complicated. 24”
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- Interpretationreasoning§ Findings from previous studies and comparison with our findings
Exposure delivered in virtual reality produced weaker outcomes than those reported in other trials.
“in virtuo exposure was less effective than in other published trials”
Quote in the paperSubstantial claim - Premisecitation§ Findings from previous studies and comparison with our findings
In Kampmann et al.'s trial, the patient and therapist were in separate rooms during virtual reality exposure exercises.
“Indeed, in Kampmann et al's study, 24 patient and therapist were in two separate rooms during exposure exercises with VR.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [24] source
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- Premisecitation§ Findings from previous studies and comparison with our findings
Anderson et al found no differences in treatment outcomes between individual cognitive-behavioural therapy with in virtuo exposure to public-speaking situations and group cognitive-behavioural therapy using in vivo exposure for people diagnosed with social anxiety disorder.
“In a randomised trial comparing individual CBT with in virtuo exposure to public-speaking situations with group CBT using in vivo exposure for people diagnosed with SAD, Anderson et al 21 found no differences in treatment outcomes between the two conditions.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [21] source
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- Interpretationreasoning§ Findings from previous studies and comparison with our findings
Variation in the way exposure was delivered could account for the difference between our results and previous findings.
“Differences in how exposure was conducted might explain this discrepancy.”
Quote in the paperNot a substantial claim - Interpretationreasoning§ Limitations
Matching participants on specific social stimuli would restrict therapists' ability to tailor interventions to individual patients.
“pairing participants on the basis of specific social stimuli would limit how therapists can tailor their interventions to each patient”
Quote in the paperNot a substantial claim - Interpretationreasoning§ Limitations
The observed differences could stem from subtle variations in the stimuli used, not solely from the exposure modality.
“Therefore, the differences found might be explained by subtle differences in stimuli used and not only the exposure modalities.”
Quote in the paperNot a substantial claim - Premisecitation§ Limitations
Trials comparing individual CBT with in virtuo exposure against traditional group CBT found no differences.
“Individual CBT with in virtuo exposure has been compared with traditional group CBT 21,23 and no differences were found”
Quote in the paperNot a substantial claim0 of 2 sources checked
- May combine two claims. 35
- Classified as probably not a substantial claim. 39
May combine two claims.
Findingown data§ Clinical outcome measuresAt the 6-month follow-up, there was a significant time effect across all outcomes from pre-treatment to follow-up, and no significant change between post-treatment and follow-up.
“As regards the 6-month follow-up analyses, there was a significant time effect across all outcomes from pre-treatment to follow-up, and no significant change between post-treatment and follow-up (Table 4).”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown data§ Clinical outcome measuresPlanned contrasts revealed significantly decreased scores in the active treatment conditions compared with the waiting list, and no differences between cognitive-behavioural therapy conditions across all outcomes except the Liebowitz Social Anxiety Scale-Self Reported version and the Social Phobia Scale, where in virtuo exposure was more effective than in vivo exposure.
“Planned contrasts revealed significantly decreased scores in the active treatment conditions compared with the waiting list, and no differences between CBT conditions across all outcomes except the LSAS-SR and the SPS, where CBT with in virtuo exposure was more effective than CBT with in vivo exposure.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown data§ ResultsConducting exposure in virtual reality was more effective at post-treatment than in vivo exposure on the primary outcome measure and on one secondary measure.
“Conducting exposure in VR was more effective at post-treatment than in vivo on the primary outcome measure and on one secondary measure.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown data§ Clinical outcome measuresAnalyses with the waiting-list condition revealed statistically significant effects of time and time-by-condition interaction across all outcome measures.
“Analyses with the waiting-list condition revealed statistically significant effects of time and time6condition interaction across all outcome measures (Table 3).”
Quote in the paperSubstantial claimMay combine two claims.
Findingown data§ ResultsIn both cognitive-behavioural therapy groups compared with the waiting list, improvements were found on the primary outcome measure and all five secondary outcome measures.
“Improvements were found on the primary (Liebowitz Social Anxiety Scale) and all five secondary outcome measures in both CBT groups compared with the waiting list.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingown data§ Clinical outcome measuresThe mean Specific Work for Exposure Applied in Therapy rating for practicality and effort was 15.24.
“How practical and effortless it was for therapists conducting the exposure, as measured with the SWEAT, was rated at 15. 24”
Quote in the paperNot a substantial claimMay combine two claims.
Findingcitation§ Findings from previous studies and comparison with our findingsOur success rates were considerably higher than those reported by Kampmann et al. and matched those of other social anxiety disorder studies.
“the success rates were much higher and consistent with other studies on SAD than those found by Kampmann et al. 24”
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Findingown data§ Clinical outcome measuresReliable change from pre- to post-treatment was observed in 76.5% (13/17) of participants who received cognitive-behavioural therapy with in virtuo exposure, 68.3% (15/22) who received cognitive-behavioural therapy with in vivo exposure, and 30.0% (6/20) in the waiting-list condition.
“Reliable change from pre-to post-treatment was observed in 76.5% (n = 13/17) of participants who had received CBT with in virtuo exposure, 68.3% (n = 15/22) who had received CBT with in vivo exposure, and 30.0%(n = 6/20) in the waiting-list condition (w 2 (2) = 9.78, P50.01).”
Quote in the paperSubstantial claimMay combine two claims.
Findingown data§ Main findingsAt post-treatment, virtual reality was more effective than traditional exposure on the Liebowitz Social Anxiety Scale-Self Reported version and the Social Phobia Scale; the Social Phobia Scale difference did not reach the corrected significance level at follow-up.
“At post-treatment, VR was more effective than traditional exposure on the main outcome measure (LSAS-SR) and one of the five secondary outcome measures (SPS, a global assessment of social anxiety).The latter difference did not reach the corrected significance level at follow-up.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown data§ Main findingsVirtual reality was neither more nor less effective than traditional exposure on the behavioural measure and on measures of fear of social interactions, fear of negative evaluation, and depressive mood.
“VR was neither more nor less effective than traditional exposure on the behavioural measure and on the measures of fear of social interactions, fear of negative evaluation and depressive mood.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingnone given§ ImplicationsSWEAT results now supply this information.
“Results on the SWEAT are now providing this information.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown data§ Main findingsThe success rate in terms of reliable change index was high and similar in both active treatment conditions.
“The success rate in terms of reliable change index was high and similar in both active treatment conditions.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Findingcitation§ Findings from previous studies and comparison with our findingsSWEAT results indicated that exposure was easier to conduct in virtual reality, which allowed greater use of the exposure experiences.
“First, results on the SWEAT revealed that conducting exposure was simpler in VR, making it possible to exploit the exposure experiences more.”
Quote in the paperNot a substantial claimMay combine two claims.
Premisecitation§ IntroductionPsychotherapy can be perceived by patients with social anxiety disorder as highly frightening or as a threat to their privacy.
“Moreover, psychotherapy itself can be perceived as highly frightening or a threat to their need for privacy. 6”
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Study design and conductnone given§ MethodThe trial was registered with ISRCTN: 99747069.
“The trial was registered with ISRCTN: 99747069.”
Quote in the paperNot a substantial claimMay combine two claims.
Study design and conductcitation§ Therapist intervention adherence and qualityTreatment standardisation was maximised using treatment manuals and treatment fidelity was maximised through weekly supervisions from the principal investigator.
“Treatment standardisation was maximised using treatment manuals 44 and treatment fidelity was maximised through weekly supervisions from the principal investigator.”
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Study design and conductcitation§ Therapist intervention adherence and qualityAdherence to research protocols was assessed by independent raters who reviewed videos of therapy sessions.
“Adherence to research protocols was also assessed by independent raters who reviewed videos of therapy sessions based on a grid used in previous CBT studies. 45”
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Premisereasoning§ IntroductionUsing virtual reality with social anxiety disorder requires a larger range of scenarios, cues eliciting social fears, and virtual environments than with specific phobias.
“Compared with phobias, using VR with SAD requires a larger range of scenarios, cues eliciting social fears and virtual environments.”
Quote in the paperNot a substantial claimMay combine two claims.
Interpretationcitation§ ConclusionsTherapists can vary the context of immersion without leaving the office, allowing complete confidentiality and maximising generalisation of inhibitory learning.
“Therapists also have the possibility of varying the context of immersion (for example shops, restaurants) without ever leaving the office, allowing for complete confidentiality and maximising the generalisation of inhibitory learning. 15”
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Premisereasoning§ IntroductionIn vivo exposure exercises raise issues regarding arousal and loss of privacy and may be cumbersome for therapists.
“However, in vivo exposure exercises (for example asking for the time on the street, browsing in a shop) raise the same issues regarding arousal and loss of privacy as CBT in a group format and may be cumbersome for therapists”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Premisecitation§ IntroductionSocial anxiety disorder remains largely undertreated despite being frequent, severe, and having effective treatments available.
“Paradoxically, despite its frequency, severity and the existence of effective treatments, SAD remains largely undertreated. 2,3”
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Premisecitation§ IntroductionPeople with social anxiety disorder tend to avoid healthcare services in the same way they avoid other social interactions.
“Patients with SAD seem to avoid healthcare services like they do other social interactions. 3,4”
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Study design and conductnone given§ MethodThe institutional review board approved the protocol and all patients provided written informed consent after receiving a complete description of the study.
“The institutional review board approved the protocol and all patients provided written informed consent after receiving a complete description of the study.”
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Premisecitation§ IntroductionIndividual cognitive-behavioural therapy can overcome the limits of the group format.
“Therapy in an individual setting can be an alternative to the group format that overcomes those limits. 11”
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Study design and conductnone given§ StatisticsIntent-to-treat analyses based on all participants who completed the baseline assessment were conducted using last-observation carried-forward for those who did not complete treatment.
“Intent-to-treat analyses based on data from all participants who completed the baseline assessment (Fig. 1) were conducted using the last-observation carried-forward for those who did not complete treatment.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Premisecitation§ IntroductionPatients with social anxiety disorder often wait many years before consulting, by which time complications have already occurred.
“Patients with SAD often wait many years while their symptoms evolve before consulting, by which time complications have already occurred. [2][3]][4]”
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Interpretationreasoning§ ConclusionsThe use of virtual scenarios allows for controlled, manageable and reproducible social exposure.
“The use of virtual scenarios allows for controlled, manageable and reproducible social exposure.”
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Premisecitation§ IntroductionVirtual reality technologies have been used extensively with specific phobias, but their applications now extend to more complex disorders.
“These technologies have been used extensively with specific phobias (such as fear of flying) but their applications now extend to more complex disorders (for example obsessive-compulsive disorder, generalised anxiety disorder). 13”
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Study design and conductnone given§ Selection criteriaAll diagnoses were reviewed and confirmed by a second assessor.
“all diagnoses were reviewed and confirmed by a second assessor”
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Study design and conductown data§ Systematic assessmentThe speech behaviour was evaluated by three independent assessors masked to hypotheses and treatment conditions.
“The speech was video recorded and the patients' behaviour was evaluated using the Social Performance Rating Scale (SPRS) 32 by three independent assessors, masked to hypotheses and treatment conditions.”
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Interpretationreasoning§ ConclusionsUsing virtual reality can be advantageous over standard cognitive-behavioural therapy as a potential solution for treatment avoidance and as an efficient, cost-effective and practical medium of exposure.
“Using VR can be advantageous over standard CBT as a potential solution for treatment avoidance and as an efficient, cost-effective and practical medium of exposure.”
Quote in the paperSubstantial claimClassified as probably not a substantial claim. May combine two claims.
Premisereasoning§ IntroductionVirtual reality or in virtuo exposure can overcome the drawbacks of standard cognitive-behavioural therapy.
“These drawbacks of standard CBT can be overcome with an alternative medium of exposure: virtual reality (VR) or in virtuo exposure”
Quote in the paperSubstantial claimMay combine two claims.
Premisecitation§ IntroductionPeople with social anxiety disorder feel ashamed of their symptoms and fear discussing them with others, including healthcare professionals.
“They feel ashamed of their symptoms and fear discussing them with others, including healthcare professionals. 5”
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Premisecitation§ IntroductionThe consensus in psychotherapy for social anxiety disorder calls for cognitive-behavioural therapy in either individual or group format.
“The consensus in the field of psychotherapy calls for cognitive-behavioural therapy (CBT) either in an individual or group format. 9,10”
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Premisecitation§ IntroductionGroup cognitive-behavioural therapy has limitations: treatment may be less individualised and exposure may be difficult for the therapist to manage.
“Because of the need to manage a whole group of people, treatment may be less individualised and exposure difficult to handle for the therapist.”
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Study design and conductcitation§ StatisticsA power analysis was conducted using effect sizes from previous studies.
“When planning the study, a power analysis was conducted using effect sizes from previous studies. 11,18,23”
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- Rests on an assumption: In vivo exposure is the gold-standard condition for cognitive-behavioural therapy in social anxiety disorder.
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Study design and conductnone given§ Selection criteriaRandom assignments were generated with a random numbers table prior to recruitment.
“Random assignments were generated with a random numbers table prior to recruitment.”
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Study design and conductown data§ Systematic assessmentThe primary outcome was identified before the study began as the total score on the Liebowitz Social Anxiety Scale-Self Reported version.
“The primary outcome was identified before the study began as the total score on the Liebowitz Social Anxiety Scale-Self Reported version (LSAS-SR)”
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Premisecitation§ IntroductionEffective treatments for social anxiety disorder rely on medication or psychotherapy.
“There are effective treatments for SAD that rely on medication or psychotherapy. [7][8]8][9]”
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Study design and conductown data§ Recruitment and attritionNone of the paired t-tests suggested a significant increase in Simulator Sickness Questionnaire scores across sessions.
“Paired t-tests were conducted for each session and none suggested a significant increase in SSQ scores (statistics not reported, all P40.2).”
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Study design and conductnone given§ Selection criteriaAssignments were concealed until the first therapy session began.
“Assignments were concealed until the first therapy session began.”
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Study design and conductreasoning§ TherapyCognitive-behavioural therapy with in virtuo exposure followed the same methodology as cognitive-behavioural therapy with in vivo exposure, with the only difference being that it exclusively used virtual reality immersion to conduct exposure and no in vivo exposure.
“CBT with in virtuo exposure followed the same methodology as CBT with in vivo exposure, with the only difference that it exclusively used VR immersion to conduct exposure (i.e.no in vivo exposure).”
Quote in the paperSubstantial claim- Rests on an assumption: Participants in the in virtuo condition complied with the instruction not to engage in any in vivo exposure.
May combine two claims.
Interpretationown data§ Main findingsResults confirmed both hypotheses: conducting cognitive-behavioural therapy with in virtuo exposure was effective and more practical for therapists than cognitive-behavioural therapy with in vivo exposure.
“Results confirmed both hypotheses: conducting CBT with in virtuo exposure was effective and more practical for therapists than CBT with in vivo exposure.”
Quote in the paperSubstantial claim- Rests on an assumption: In vivo exposure is the gold-standard condition for cognitive-behavioural therapy in social anxiety disorder.
May combine two claims.
Study design and conductown data§ LimitationsBehavioural assessments were used instead and corroborated the self-report findings.
“Behavioural assessments were chosen instead and support results found with self-reports.”
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Interpretationreasoning§ Findings from previous studies and comparison with our findingsThe restriction of exposure to conversations with virtual characters, together with the lack of a cognitive component, could account for the lower effectiveness of in virtuo exposure compared with other trials.
“Limiting exposure to talking to virtual characters and the absence of a cognitive component that facilitates how exposure is mentally processed by patients may explain why in virtuo exposure was less effective than in other published trials.”
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Premisecitation§ Findings from previous studies and comparison with our findingsIn Anderson et al, patients improved significantly with treatment and improvements were maintained after 1 year.
“Patients improved significantly with treatment and improvements were maintained after 1 year.”
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Premisecitation§ ImplicationsNew virtual environments can depict more complex social interactions and use virtual characters with promising artificial intelligence.
“New virtual environments can now depict more complicated social interactions 15 and rely on virtual characters with promising artificial intelligence. 24”
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Interpretationreasoning§ ImplicationsSince virtual reality exposure is less cumbersome and becoming more affordable, acceptance of the technology should increase.
“Because conducting exposure in VR is less cumbersome and rapidly becoming more affordable, there should be an increase in acceptance of this technology.”
Quote in the paperNot a substantial claim- Rests on an assumption: Virtual reality is rapidly becoming more affordable.
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Interpretationnone given§ ImplicationsA key contribution of this study is its use of a measure that assesses the burden, challenges and costs of conducting exposure.
“One important contribution of this study is the use of a measure assessing the burden, challenges and costs of conducting exposure.”
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Interpretationreasoning§ Findings from previous studies and comparison with our findingsLack of direct therapist support may have harmed the therapeutic alliance and thereby lowered the effectiveness of in virtuo exposure.
“The absence of direct support from the therapist might have had a negative impact on the therapeutic alliance and thus might have reduced the efficacy of in virtuo exposure.”
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Premisecitation§ Findings from previous studies and comparison with our findingsPrevious studies have shown that giving a speech in front of a virtual audience can elicit distress and physiological arousal in patients with social anxiety disorder.
“Previous studies have shown that giving a speech in front of a virtual audience can elicit distress and physiological arousal in patients with SAD. 17”
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Premisecitation§ Findings from previous studies and comparison with our findingsNumerous studies have shown the efficacy of in virtuo exposure for treating fear about public speaking.
“Numerous studies have also shown the efficacy of in virtuo exposure for treating fear about public speaking. [18][19]9][20]”
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Interpretationown data§ Findings from previous studies and comparison with our findingsBecause therapeutic alliance predicted outcome, the therapist's role in delivering exposure is important.
“Second, the importance of the therapeutic alliance in predicting outcome highlights the importance of the therapists in conducting exposure.”
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Premisecitation§ Findings from previous studies and comparison with our findingsIn Anderson et al, the quality of the working alliance was not different between the two treatment conditions.
“Furthermore, the quality of the working alliance was not different in the two treatment conditions. 22”
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Premisecitation§ Findings from previous studies and comparison with our findingsKampmann et al's randomised controlled trial found that participants in both treatment conditions improved from pre- to post-assessment on social anxiety, avoidance, speech duration during a behavioural assessment task, perceived stress, and avoidant personality disorder related beliefs compared with the waiting-list control group.
“Results revealed that participants in both treatment conditions improved from pre-to postassessment on social anxiety, avoidance, speech duration during a behavioural assessment task, perceived stress, and avoidant personality disorder related beliefs when compared with the waiting-list control group. 24”
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Interpretationreasoning§ LimitationsAn RCT in which all stimuli were perfectly matched across conditions would have greater validity.
“Nevertheless, conducting an RCT with all stimuli perfectly matched between conditions would increase the validity of the trial.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductreasoning§ LimitationsThe absence of independent, masked clinical assessors raises concerns about the objectivity of questionnaire-based clinical assessments.
“First, the lack of clinical evaluations by independent assessors masked to the study raises the potential issues of the objectivity of clinical assessments using questionnaires.”
Quote in the paperNot a substantial claimMay combine two claims.
Interpretationcitation§ Main findingsThese results support what has been found with other anxiety disorders and show that cognitive-behavioural therapy combined with exposure in virtual reality is an effective and efficient alternative to classical individual cognitive-behavioural therapy, acutely and in the long term.
“These results support what has been found with other anxiety disorders 13 and show that CBT combined with exposure in VR is an effective and efficient alternative to classical individual CBT, acutely and in the long term.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [13]
Not checked in the free run.
Probably not a substantial claim: may not pass S2 (checkable), S3 (load-bearing), S4 (based). May combine two claims.
Interpretationnone given§ LimitationsIndividual virtual reality exposure may appeal more to patients who avoid social exposure or who require strict confidentiality about their disorder.
“However, individual exposure with VR may be more enticing to patients disinclined from social exposure or sensitive to strict confidentiality concerning their disorder.”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim.
Premisecitation§ Findings from previous studies and comparison with our findingsKampmann et al found cognitive-behavioural therapy with in vivo exposure superior to cognitive-behavioural therapy with in virtuo exposure on multiple variables such as social anxiety and personality disorder related beliefs.
“However, CBT with in vivo exposure was found superior to CBT with in virtuo exposure on multiple variables (such as social anxiety, personality disorder related beliefs).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [24] source
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Premisecitation§ LimitationsThat study concerned specific phobia of heights, and its exposure scenarios were limited to three situations.
“However, this was a study on the specific phobia of heights, the exposure scenarios were limited to three situations”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [46]
Not checked in the free run.
The paper relies on this without support.
In vivo exposure is the gold-standard condition for cognitive-behavioural therapy in social anxiety disorder.
“large with the gold-standard condition (i.e.Cohen's f of 0.4, for a total n of 78).”
The paper relies on this without support.
Participants in the in virtuo condition complied with the instruction not to engage in any in vivo exposure.
“Participants in the in virtuo condition were instructed not to engage in any exposure in vivo.”
The paper relies on this without support.
Group CBT is as effective as individual CBT and is widely used.
“although the group format is equally effective and widely used”
The paper relies on this without support.
Therapists may be reluctant to adopt virtual reality.
“Therapists may be reluctant to use VR”
The paper relies on this without support.
Virtual reality is rapidly becoming more affordable.
“rapidly becoming more affordable”
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Cognitive-behavioral therapy (CBT) with exposure in virtual reality (VR) is a promising intervention for treating speaking anxiety in pediatric populations.
“Cognitive-behavioral therapy (CBT) with exposure in virtual reality (VR) emerges as a promising intervention for treating speaking anxiety in pediatric populations.”
From Speaking face-to-face with a virtual avatar to reduce anxiety in students who stutter: Tool development and pilot study results. (2026) · cites this paper as Bouchard et al., 2017
The Results report improved social-anxiety outcomes with CBT using VR exposure, and the In virtuo exposure section includes speaking before a virtual audience. But the Selection criteria limit participants to ages 18–65, so the study does not establish effectiveness in pediatric populations; it also evaluates social anxiety disorder rather than speaking anxiety alone. Page numbers were not available in our copy. (LLM, conf=0.90)
Experimental — accuracy not yet measuredTherapists have no control over in vivo treating context, which can elevate patient arousal and raise privacy issues.
“In addition, therapists have no control over in vivo treating context, which can elevate patient arousal and raise privacy issues (Bouchard et al., 2017; Stangier et al., 2003).”
From Speaking face-to-face with a virtual avatar to reduce anxiety in students who stutter: Tool development and pilot study results. (2026) · cites this paper as Bouchard et al., 2017
The opening discussion of CBT limitations says in vivo exposure can raise arousal and privacy concerns. But “no control” over the treatment context is too absolute: the In vivo exposure section describes therapist-guided exercises adjusted to patients’ needs, while the Conclusions contrast these with the greater control offered by virtual scenarios. Page numbers are not available in the supplied passages. (LLM, conf=0.85)
Experimental — accuracy not yet measuredVirtual reality treatment for anxiety-related disorders is effective and particularly useful for social anxiety.
“The virtual reality method of treating anxiety-related disorders is effective and especially useful for tackling social anxiety.”
From Fear and Anxiety in COVID-19: Preexisting Anxiety Disorders (2021) · cites this paper as Bouchard et al., 2017
Experimental — accuracy not yet measuredIn an RCT in SAD patients, both CBT with VRET and CBT with exposure in vivo significantly reduced self-reported SAD symptoms compared to waitlist, and VRET exceeded in vivo on the primary outcome measure.
“While both exposure conditions were of comparable efficacy regarding most outcome measures, VRET exceeded the in vivo condition in the primary outcome measure, with significantly greater symptom reductions in patients receiving exposure in virtuo.”
From Virtual Reality exposure therapy in the treatment of public speaking anxiety and social anxiety disorder (2024) · cites this paper as Bouchard et al., 2017
Exposure-based interventions addressing social fears can be resource-intensive and time-consuming.
“Exposure-based interventions addressing social fears can be resource-intensive and time-consuming due to the need to facilitate exposure exercises often outside the safety of a standardized, closely measured and accompanied environment (Reeves et al., 2022; Bouchard et al., 2017).”
From Virtual Reality exposure therapy in the treatment of public speaking anxiety and social anxiety disorder (2024) · cites this paper as Bouchard et al., 2017
Apart from public speaking, job interviews comprised a considerable amount of exposure situations in VRET studies.
“Apart from public speaking situations, job interviews comprised a considerable amount of exposure situations (e.g., Bouchard et al., 2017; Stefaniak et al., 2022; Kampmann et al., 2016b).”
From Virtual Reality exposure therapy in the treatment of public speaking anxiety and social anxiety disorder (2024) · cites this paper as Bouchard et al., 2017
VR exposure in CBT holds potential as an alternative therapeutic technique for treating phobias and social anxiety in adults and children.
“Virtual reality (VR) exposure in CBT holds potential as an alternative therapeutic technique for treating phobias and social anxiety in adults (Bouchard et al., 2017; Chesham et al., 2018; Horigome et al., 2020; Wechsler et al., 2019) and children (Beele et al., 2024; Man et al., 2024; Parrish et al., 2016; Wong Sarver et al., 2014).”
From Speaking face-to-face with a virtual avatar to reduce anxiety in students who stutter: Tool development and pilot study results. (2026) · cites this paper as Bouchard et al., 2017
In Bouchard et al. (2017), 9 of the treatment sessions were not recorded because of technical issues.
“as is the case of the study of Bouchard et al. (2017), in which 9 of the treatment sessions were not recorded because of technical issues.”
From Virtual reality and psychedelics for the treatment of psychiatric disease: A systematic literature review (2020) · cites this paper as Bouchard et al. (2017)
The ‘Therapist intervention adherence and quality’ section says independent raters reviewed videos of therapy sessions, but does not say that any sessions went unrecorded. Searches for nine missing recordings and technical issues found no passage giving the claimed number or cause. (LLM, conf=0.70)
Experimental — accuracy not yet measuredBouchard et al. [20] is the only study presenting findings in favor of VRET condition.
“Bouchard et al. [20] is the only study presenting findings in favor of VRET condition.”
From Recent Progress in Virtual Reality Exposure Therapy for Phobias: A Systematic Review (2017) · cites this paper as [20]
Studies of patients treated with VRET and in vivo exposure therapy for social anxiety disorder found no significant difference between interventions as measured by the WAI.
“Contrary to this expectation, studies of patients treated with VRET and in vivo exposure therapy for social anxiety disorder found no significant difference between interventions as measured by the WAI [10-12].”
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
In-vivo addiction percentage is incorrect
MinorTwo participants in the in-vivo group of 22 represent 9.1%, not the reported 3.4%.
Reported 3.4 · recomputed 9.090909
“| Addiction | 5 (8.5) | 1 (5.9) | 2 (3.4) | 1 (5.0) | | | |”
White participants' overall percentage is too high
MinorThe table reports 55 White participants out of a total sample of 59. That is 93.2%, not 94.8%.
Reported 94.8 · recomputed 93.220339
“| White, n (%) | 55 (94.8) | 17 (100.0) | 21 (95.5) | 17 (85.0) | 5.88 | | |”
Low-income percentage does not match the count
MinorSixteen of the 59 participants is 27.1%, rather than the reported 21.1%.
Reported 21.1 · recomputed 27.118644
“| Low income, n (%) | 16 (21.1) | 4 (23.5) | 5 (22.7) | 7 (35.0) | 2.93 | | |”
Medication percentage does not match the sample size
MinorThe reported nine participants represent 15.3% of the stated total sample of 59, not 16.7%.
Reported 16.7 · recomputed 15.254237
“| Medication, n (%) | 9 (16.7) | 2 (11.8) | 3 (13.6) | 4 (20.0) | 1.58 | | |”
Addiction count does not equal the group counts
MinorThe three group counts for addiction add to four participants, whereas the total column reports five.
Reported 5 · recomputed 4
“| Addiction | 5 (8.5) | 1 (5.9) | 2 (3.4) | 1 (5.0) | | | |”
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“VR also affords the possibility of various scenarios and stimuli tailored to individual needs, reduced inconsistency of treatment delivery, as well as eliminating the need for real-world stimuli that might be difficult to procure and/or manipulate in a therapeutic context (Bouchard et al., 2017; Freeman et al., 2017;…”
BackgroundPerception of avatars nonverbal behaviors in virtual reality
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- Authors
- Bouchard, S., Dumoulin, S., Robillard, G., Guitard, T., Klinger, É., Forget, H., Loranger, C., & Roucaut, F. X.
- Affiliations
- Université du Québec en Outaouais (CA)
- Corresponding author
- Bouchard, Stéphane
- Venue
- British Journal of Psychiatry
- Publisher
- Royal College of Psychiatrists
- Published
- 2017-04
- Volume
- 210
- Issue
- 4
- Pages
- 276-283
- ISSN
- 0007-1250 (ISSN-L)
- 1472-1465
- OpenAlex
- W2565451694
- Cited by
- 354
- References
- 45
- Citations by year
- 2026: 28 · 2025: 38 · 2024: 45 · 2023: 48 · 2022: 39 · 2021: 51 · 2020: 39 · 2019: 31 · 2018: 25 · 2017: 10
- FWCI
- 31.23
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- The British Journal of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Canada Research Chairs (950-10762)
- Social Sciences and Humanities Research Council of Canada (10762)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Physical Sciences › Computer Science › Human-Computer Interaction › Virtual Reality Applications and Impacts
- Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
- Keywords
- social anxiety disorder, virtual reality exposure, in vivo exposure, cognitive behavioral therapy, exposure therapy, treatment avoidance, maintenance therapy, cost-effectiveness
- MeSH terms
- Phobia, Social, Adult, Female, Humans, Implosive Therapy, Male, Middle Aged, User-Computer Interface, Cognitive Behavioral Therapy, Outcome Assessment, Health Care
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