Neural stem cells: balancing self-renewal with differentiation

Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors

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Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells

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Cortical neurons arise in symmetric and asymmetric division zones and migrate through specific phases

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The cell biology of neurogenesis

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The Diverse Functions of MicroRNAs in Animal Development and Disease

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Neurons derived from radial glial cells establish radial units in neocortex

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Wnt signalling regulates adult hippocampal neurogenesis

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Proneural genes and the specification of neural cell types

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Regulation of Cerebral Cortical Size by Control of Cell Cycle Exit in Neural Precursors

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SOX2 Functions to Maintain Neural Progenitor Identity

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Control of Neuronal Precursor Proliferation in the Cerebellum by Sonic Hedgehog

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Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation

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Neurons arise in the basal neuroepithelium of the early mammalian telencephalon: A major site of neurogenesis

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REST and Its Corepressors Mediate Plasticity of Neuronal Gene Chromatin throughout Neurogenesis

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Vertebrate neural cell-fate determination: Lessons from the retina

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Asymmetric Inheritance of Radial Glial Fibers by Cortical Neurons

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Vertebrate neurogenesis is counteracted by Sox1–3 activity

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Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo

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Negative Regulation of Neural Stem/Progenitor Cell Proliferation by the Pten Tumor Suppressor Gene in Vivo

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Asymmetric production of surface-dividing and non-surface-dividing cortical progenitor cells

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Cleavage orientation and the asymmetric inheritance of notchl immunoreactivity in mammalian neurogenesis

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Radial Glial Identity Is Promoted by Notch1 Signaling in the Murine Forebrain

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Sonic Hedgehog Is Required for Progenitor Cell Maintenance in Telencephalic Stem Cell Niches

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In vivo analysis of quiescent adult neural stem cells responding to Sonic hedgehog

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Notch pathway molecules are essential for the maintenance, but not the generation, of mammalian neural stem cells

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Drosophila Neuroblasts Sequentially Express Transcription Factors which Specify the Temporal Identity of Their Neuronal Progeny

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A mitogen gradient of dorsal midline Wnts organizes growth in the CNS

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Sox2 deficiency causes neurodegeneration and impaired neurogenesis in the adult mouse brain

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How widespread is adult neurogenesis in mammals?

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Conservation of the Notch signalling pathway in mammalian neurogenesis

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Toll-like receptors modulate adult hippocampal neurogenesis

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Sonic hedgehog controls stem cell behavior in the postnatal and adult brain

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The Wnt/β-catenin pathway directs neuronal differentiation of cortical neural precursor cells

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Mosaic Analysis with Double Markers in Mice

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Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways

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Notch signaling in the mammalian central nervous system: insights from mouse mutants

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Hes genes regulate size, shape and histogenesis of the nervous system by control of the timing of neural stem cell differentiation

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The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl

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Asymmetric Segregation of the Tumor Suppressor Brat Regulates Self-Renewal in Drosophila Neural Stem Cells

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Differential Notch signalling distinguishes neural stem cells from intermediate progenitors

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Musashi1: An Evolutionally Conserved Marker for CNS Progenitor Cells Including Neural Stem Cells

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Neuroepithelial progenitors undergo LGN-dependent planar divisions to maintain self-renewability during mammalian neurogenesis

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Asymmetric segregation of Numb and Prospero during cell division

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β-Catenin signals regulate cell growth and the balance between progenitor cell expansion and differentiation in the nervous system

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Induction of tumor growth by altered stem-cell asymmetric division in Drosophila melanogaster

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A small modulatory dsRNA specifies the fate of adult neural stem cells

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The many faces of REST oversee epigenetic programming of neuronal genes

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Asymmetric distribution of the apical plasma membrane during neurogenic divisions of mammalian neuroepithelial cells

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Aspm specifically maintains symmetric proliferative divisions of neuroepithelial cells

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p53 suppresses the self-renewal of adult neural stem cells

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Prospero Acts as a Binary Switch between Self-Renewal and Differentiation in Drosophila Neural Stem Cells

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Roles of the Basic Helix-Loop-Helix Genes Hes1 and Hes5 in Expansion of Neural Stem Cells of the Developing Brain

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Cell polarity in development and cancer

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Persistent expression of helix-loop-helix factor HES-1 prevents mammalian neural differentiation in the central nervous system.

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The Rho-GTPase cdc42 regulates neural progenitor fate at the apical surface

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NUMB controls p53 tumour suppressor activity

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Progressive restriction in fate potential by neural progenitors during cerebral cortical development

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The prospero transcription factor is asymmetrically localized to the cell cortex during neuroblast mitosis in Drosophila

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An inhibition of cyclin-dependent kinases that lengthens, but does not arrest, neuroepithelial cell cycle induces premature neurogenesis

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Musashi, a neural RNA-binding protein required for drosophila adult external sensory organ development

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Mitotic Spindle Regulation by Nde1 Controls Cerebral Cortical Size

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Loss of cell polarity causes severe brain dysplasia in Lgl1 knockout mice

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Lgl, Pins and aPKC regulate neuroblast self-renewal versus differentiation

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Progenitor cell maintenance requires numb and numblike during mouse neurogenesis

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The PROSPERO transcription factor is asymmetrically localized to the cell cortex during neuroblast mitosis in Drosophila

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Brat Is a Miranda Cargo Protein that Promotes Neuronal Differentiation and Inhibits Neuroblast Self-Renewal

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The NuMA-related Mud protein binds Pins and regulates spindle orientation in Drosophila neuroblasts

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Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors

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β1 integrins activate a MAPK signalling pathway in neural stem cells that contributes to their maintenance

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Spatial and temporal specification of neural fates by transcription factor codes

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PTEN negatively regulates neural stem cell self-renewal by modulating G 0 -G 1 cell cycle entry

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The Drosophila NuMA Homolog Mud Regulates Spindle Orientation in Asymmetric Cell Division

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Functionally Unequal Centrosomes Drive Spindle Orientation in Asymmetrically Dividing Drosophila Neural Stem Cells

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Drosophila aPKC regulates cell polarity and cell proliferation in neuroblasts and epithelia

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Staufen-dependent localization of prospero mRNA contributes to neuroblast daughter-cell fate

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The brain tumor gene negatively regulates neural progenitor cell proliferation in the larval central brain of Drosophila

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Numb is a suppressor of Hedgehog signalling and targets Gli1 for Itch-dependent ubiquitination

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Hedgehog-GLI signaling regulates the behavior of cells with stem cell properties in the developing neocortex

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Aurora-A acts as a tumor suppressor and regulates self-renewal of Drosophila neuroblasts

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Control of planar divisions by the G-protein regulator LGN maintains progenitors in the chick neuroepithelium

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Drosophila Aurora-A kinase inhibits neuroblast self-renewal by regulating aPKC/Numb cortical polarity and spindle orientation

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Drosophila Pins-binding protein Mud regulates spindle-polarity coupling and centrosome organization

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A role for a novel centrosome cycle in asymmetric cell division

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αE-Catenin Controls Cerebral Cortical Size by Regulating the Hedgehog Signaling Pathway

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G Protein βγ Subunits and AGS3 Control Spindle Orientation and Asymmetric Cell Fate of Cerebral Cortical Progenitors

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Notch1 and its ligands Delta-like and Jagged are expressed and active in distinct cell populations in the postnatal mouse brain

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Strengths and Limitations of the Neurosphere Culture System

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deadpan, an essential pan-neural gene in Drosophila, encodes a helix-loop-helix protein similar to the hairy gene product.

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The presence of FGF2 signaling determines whether β-catenin exerts effects on proliferation or neuronal differentiation of neural stem cells

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aPKC‐mediated phosphorylation regulates asymmetric membrane localization of the cell fate determinant Numb

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PTENless means more

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Presenilin-1 regulates neuronal differentiation during neurogenesis

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Role of β-catenin in the developing cortical and hippocampal neuroepithelium

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Interacting signalling pathways regulating prestalk cell differentiation and movement during the morphogenesis of Dictyostelium

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Pan-neural Prospero terminates cell proliferation during Drosophila neurogenesisPreprint

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Cell-Autonomous β-Catenin Signaling Regulates Cortical Precursor Proliferation

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Regulation of neuroblast competence in Drosophila

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