Student or educator? Sign up with your school email and get 6 months of Pro free.
CoChat
Sign Up
Cited by 319

The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.

Historical Comparison of Perfluorooctanesulfonate, Perfluorooctanoate, and Other Fluorochemicals in Human Blood

Open access
Olsen, Geary W., Huang, Han-Yao, Helzlsouer, Kathy J., Hansen, Kristen J., Butenhoff, John L., Mandel, Jeffrey H.·2005·Environmental Health Perspectives
DOI 10.1289/ehp.7544
Open this paper in CoChat — free account

Abstract

The purpose of this investigation was to determine whether there has been a change in the human blood concentration of perfluorooctanesulfonate (PFOS), perfluorooctanoate (PFOA), and five other fluorochemicals since 1974. Blood samples were collected in 1974 (serum) and 1989 (plasma) from volunteer participants of a large community health study. The study included a total of 356 samples (178 from each time period). These samples were analyzed by high-pressure liquid chromatography/tandem mass spectrometry methods. The median 1974 and 1989 fluorochemical concentrations, respectively, were as follows: PFOS, 29.5 ng/mL vs. 34.7 ng/mL; PFOA, 2.3 ng/mL vs. 5.6 ng/mL; perfluorohexanesulfonate (PFHS), 1.6 ng/mL vs. 2.4 ng/mL; and N-ethyl perfluorooctanesulfonamidoacetate (PFOSAA), less than the lower limit of quantitation (LLOQ; 1.6 ng/mL, vs. 3.4 ng/mL). For N-methyl perfluorooctanesulfonamidoacetate (M570), perfluorooctanesulfonamide, and perfluorooctanesulfonamidoacetate, median serum concentrations in both years were less than the LLOQ values (1.0, 1.0, and 2.5 ng/mL, respectively). Statistical analysis of 58 paired samples indicated that serum concentrations of PFOS, PFOSAA, PFOA, PFHS, and M570 were significantly (p < 0.001) higher in 1989 than in 1974. The data from 1989 were then compared with geometric mean fluorochemical concentrations of serum samples collected in 2001 from 108 American Red Cross adult blood donors from the same region. Except for M570, there were no statistically significant (p < 0.05) geometric mean fluorochemical concentration differences between the 1989 and 2001 samples. In conclusion, based on this study population, PFOS and other serum fluorochemical concentrations have increased between 1974 and 1989. Comparison with other regional data collected in 2001 did not suggest a continued increase in concentrations since 1989.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1289/ehp.7544

Cites

9 of 9 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 9 references

Research works printed but not linked: 30

  1. Biegel, 2001, Mechanisms of extrahepatic induction of peroxisome proliferators in male CD rats, Toxicol Sci, 60, 44, 10.1093/toxsci/60.1.44 · DOI · Paper page
  2. Butenhoff, 2004, Characterization of risk for general population exposure to perfluorooctanoate, Regul Toxicol Pharmacol, 39, 363, 10.1016/j.yrtph.2004.03.003 · DOI
  3. Comstock, 1997, The risk of developing lung cancer associated with antioxidants in the blood: ascorbic acid, carotenoids, alpha-tocopherol, selenium and total peroxyl radical absorbing capacity, Cancer Epidemiol Biomarkers Prev, 6, 907
  4. Comstock, 1988, Serum levels of retinol, beta-carotene, and alpha-tocopherol in older adults, Am J Epidemiol, 127, 114, 10.1093/oxfordjournals.aje.a114771 · DOI
  5. Hagen, 1981, Characterization of fluorinated metabolites by a gas chromatographic-helium microwave plasma detector—the biotransformation of 1H,1H,2H,2H-perfluorodecanol to perfluorooctanoate, Anal Biochem, 118, 336, 10.1016/0003-2697(81)90591-1 · DOI
  6. Hansen, 2002, Quantitative characterization of trace levels of PFOS and PFOA in the Tennessee River, Environ Sci Technol, 36, 1681, 10.1021/es010780r · DOI · Paper page
  7. Haughom, 1992, The mechanism underlying the hypolipemic effect on perfluorooctanoic acid (PFOA), perfluorooctane sulphonic acid (PFOSA) and clofibric acid, Biochim Biophys Acta, 1128, 65, 10.1016/0005-2760(92)90258-W · DOI
  8. Hu, 2002, Comparisons among perfluorinated compounds of effects on gap junctional intercellular communication, Toxicol Sci, 68, 429, 10.1093/toxsci/68.2.429 · DOI
  9. Inoue, 2004, Perfluorooctane sulfonate (PFOS) and related perfluorinated compounds in human maternal and cord blood samples: assessment of PFOS exposure in susceptible population during pregnancy, Environ Health Perspect, 112, 1204, 10.1289/ehp.6864 · DOI · Paper page
  10. Johnson, 1984, Cholestyramine-enhanced fecal elimination of carbon-14 in rats after administration of ammonium [14C]perfluorooctanoate or potassium [14C]perfluorooctanesulfonate, Fundam Appl Toxicol, 4, 972, 10.1016/0272-0590(84)90235-5 · DOI
  11. Kannan, 2002, Concentrations of perfluorinated acids in livers of birds from Japan and Korea, Chemosphere, 49, 225, 10.1016/S0045-6535(02)00304-1 · DOI
  12. Kannan, 2002, Perfluorooctanesulfonate and related fluorinated hydrocarbons in marine mammals, fishes, and birds from coasts of the Baltic and Mediterranean Seas, Environ Sci Technol, 36, 3210, 10.1021/es020519q · DOI · Paper page
  13. Kannan, 2001, Perfluorooctane sulfonate in fish-eating water birds including bald eagles and albatrosses, Environ Sci Technol, 35, 3065, 10.1021/es001935i · DOI · Paper page
  14. Kannan, 2001, Accumulation of perfluorooctane sulfonate in marine mammals, Environ Sci Technol, 35, 1593, 10.1021/es001873w · DOI · Paper page
  15. Kannan, 2002, Perfluorooctanesulfonate and related fluorinated hydrocarbons in mink and river otters from the United States, Environ Sci Technol, 36, 2566, 10.1021/es0205028 · DOI
  16. Klaunig, 2003, PPAR alpha agonist-induced rodent tumors: modes of action and human relevance, Crit Rev Toxicol, 33, 655, 10.1080/713608372 · DOI · Paper page
  17. Lau, 2003, Exposure to perfluorooctane sulfonate during pregnancy in rat and mouse. II. Postnatal evaluation, Toxicol Sci, 74, 382, 10.1093/toxsci/kfg122 · DOI · Paper page
  18. Luebker, 2002, Interactions of perfluoroalkylsulfonamides with L-FABP and BSA in-vitro, Toxicology, 176, 175, 10.1016/S0300-483X(02)00081-1 · DOI · Paper page
  19. Olsen, 2003, Epidemiologic assessment of worker serum perfluorooctanesulfonate (PFOS) and perfluorooctanoate (PFOA) concentrations and medical surveillance examinations, J Occup Environ Med, 45, 260, 10.1097/01.jom.0000052958.59271.10 · DOI · Paper page
  20. Olsen, 2003, An occupational exposure assessment of a perfluorooctanesulfonyl fluoride production site: biomonitoring, AIHAJ, 64, 651, 10.1080/15428110308984859 · DOI
  21. Olsen, 2004, Quantitative evaluation of perfluorooctanesulfonate (PFOS) and other fluorochemicals in the serum of children, J Children’s Health, 2, 53, 10.3109/15417060490447378 · DOI
  22. Olsen, 2003, Perfluorooctanesulfonate (PFOS) and other fluorochemicals in the serum of American Red Cross adult blood donors, Environ Health Perspect, 111, 1892, 10.1289/ehp.6316 · DOI · Paper page
  23. Olsen, 2003, Human donor liver and serum concentrations of perfluorooctanesulfonate and other perfluorochemicals, Environ Sci Technol, 37, 888, 10.1021/es020955c · DOI
  24. Seacat, 2002, Terminal observations in Sprague-Dawley rats after lifetime dietary exposure to potassium perfluorooctanesulfonate [Abstract], Toxicologist, 66, 185
  25. Seacat, 2003, Sub-chronic dietary toxicity of potassium perfluorooctanesulfonate in rats, Toxicology, 183, 117, 10.1016/S0300-483X(02)00511-5 · DOI · Paper page
  26. Singer, 1979, Concentrations of ionic, total, and bound fluoride in plasma, Clin Chem, 25, 523, 10.1093/clinchem/25.4.523 · DOI
  27. Starkov, 2001, Structural determinants of fluorochemical-induced mitochondrial dysfunction, Toxicol Sci, 66, 244, 10.1093/toxsci/66.2.244 · DOI
  28. Taves, 1968, Evidence that there are two forms of fluoride in human serum, Nature, 217, 1050, 10.1038/2171050b0 · DOI · Paper page
  29. Taves, 1968, Electrophoretic mobility of serum fluoride, Nature, 220, 582, 10.1038/220582a0 · DOI
  30. U.S. EPA, 2002, Perfluoroalkyl sulfonates; significant new use rule; final rule, Fed Reg, 67, 72854

Cited by

Metadata

Authors
Olsen, G. W., Huang, H.-Y., Helzlsouer, K. J., Hansen, K. J., Butenhoff, J. L., & Mandel, J. H.
Venue
Environmental Health Perspectives
Publisher
American Chemical Society (ACS)
Published
2005-05
Volume
113
Issue
5
Pages
539-545
ISSN
  • 0091-6765 (ISSN-L)
  • 1552-9924
DOI
10.1289/ehp.7544
OpenAlex
W2041925174
Cited by
319
References
9
FWCI
21.16
Type
journal article
Language
en
Open access
gold
Licence
creativecommons.org/licenses/by/4.0/ (vor, 4713 d)

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.