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Cited by 1,416

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Cortical Excitatory Neurons and Glia, But Not GABAergic Neurons, Are Produced in the Emx1-Expressing Lineage

Open access
Gorski, Jessica A., Talley, Tiffany, Qiu, Mengsheng, Puelles, Luis, Rubenstein, John L. R., Jones, Kevin R.·2002·The Journal of Neuroscience

Abstract

By homologous recombination of an internal ribosome entry site and Cre recombinase coding region into the 3'-untranslated region of the mouse Emx1 gene, we have generated a strain of mice, Emx1(IRES)cre, that expresses the Cre recombinase in a spatial and temporal pattern like that observed for Emx1. When mated to reporter strains, these mice are a sensitive means to fate-map the Emx1-expressing cells of the developing forebrain. Our results demonstrate that radial glia, Cajal-Retzius cells, glutamatergic neurons, astrocytes, and oligodendrocytes of most pallial structures originate from an Emx1-expressing lineage. On the other hand, most of the pallial GABAergic neurons arise outside the Emx1-expressing lineage. Structures that are located near the basal ganglia (e.g., the amygdala and endopiriform nuclei) are not uniformly derived from Emx1-expressing cells.

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Crossref · 10.1523/jneurosci.22-15-06309.2002

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Metadata

Authors
Gorski, J. A., Talley, T., Qiu, M., Puelles, L., Rubenstein, J. L. R., & Jones, K. R.
Venue
The Journal of Neuroscience
Published
2002-08-01
Volume
22
Issue
15
Pages
6309-6314
ISSN
  • 0270-6474 (ISSN-L)
  • 1529-2401
OpenAlex
W2162423225
Cited by
1,416
References
2
FWCI
5.22
Type
journal article
Language
en
Open access
bronze

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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