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The C. elegans intestine

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McGhee, James·2007·WormBook

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Abstract

The intestine is one of the major organs in C. elegans and is largely responsible for food digestion and assimilation as well as the synthesis and storage of macromolecules. In addition, the intestine is emerging as a powerful experimental system in which to study such universal biological phenomena as vesicular trafficking, biochemical clocks, stress responses and aging. The present chapter describes some of these many and varied properties of the C. elegans intestine: the embryonic cell lineage, intestine morphogenesis, structure and physiology of the intestinal cell and, finally, the transcription factor network controlling intestine development and function.

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The embryonic cell lineage of the nematode Caenorhabditis elegans
Sulston, J. E., Schierenberg, E., White, J. G., & Thomson, J. N. (1983) · Developmental Biology · doi:10.1016/0012-1606(83)90201-4 · Cited by 4,199
Post-embryonic cell lineages of the nematode, Caenorhabditis elegans
Sulston, J. E., & Horvitz, H. R. (1977) · Developmental Biology · doi:10.1016/0012-1606(77)90158-0 · Cited by 3,475
Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans
Murphy, C. T., McCarroll, S. A., Bargmann, C. I., Fraser, A., Kamath, R. S., Ahringer, J., Li, H., & Kenyon, C. (2003) · Nature · doi:10.1038/nature01789 · Cited by 2,280
Regulation of aging and age-related disease by DAF-16 and heat-shock factor
Hsu, A.-L., Murphy, C. T., & Kenyon, C. (2003) · Science · doi:10.1126/science.1083701 · Cited by 1,513
Autophagy Genes Are Essential for Dauer Development and Life-Span Extension in C. elegans
Meléndez, A., Tallóczy, Z., Seaman, M., Eskelinen, E.-L., Hall, D. H., & Levine, B. (2003) · Science · doi:10.1126/science.1087782 · Cited by 1,270
Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling
Lin, K., Hsin, H., Libina, N., & Kenyon, C. (2001) · Nature Genetics · doi:10.1038/88850 · Cited by 1,039
Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes
Ashrafi, K., Chang, F. Y., Watts, J. L., Fraser, A. G., Kamath, R. S., Ahringer, J., & Ruvkun, G. (2003) · Nature · doi:10.1038/nature01279 · Cited by 980
Systemic RNAi in C. elegans Requires the Putative Transmembrane Protein SID-1
Winston, W. M., Molodowitch, C., & Hunter, C. P. (2002) · Science · doi:10.1126/science.1068836 · Cited by 846
Tissue-Specific Activities of C. elegans DAF-16 in the Regulation of Lifespan
Libina, N., Berman, J. R., & Kenyon, C. (2003) · Cell · doi:10.1016/s0092-8674(03)00889-4 · Cited by 820
Evidence for evolutionary conservation of sex-determining genes
Raymond, C. S., Shamu, C. E., Shen, M. M., Seifert, K. J., Hirsch, B., Hodgkin, J., & Zarkower, D. (1998) · Nature · doi:10.1038/35618 · Cited by 802
SKN-1 links C. elegans mesendodermal specification to a conserved oxidative stress response
An, J. H., & Blackwell, T. K. (2003) · Genes & Development · doi:10.1101/gad.1107803 · Cited by 726
PERITROPHIC MATRIX STRUCTURE AND FUNCTION
Lehane, M. J. (1997) · Annual Review of Entomology · doi:10.1146/annurev.ento.42.1.525 · Cited by 726
Wnt Signaling and an APC-Related Gene Specify Endoderm in Early C. elegans Embryos
Rocheleau, C. E., Downs, W. D., Lin, R., Wittmann, C., Bei, Y., Cha, Y.-H., Ali, M., Priess, J. R., & Mello, C. C. (1997) · Cell · doi:10.1016/s0092-8674(00)80531-0 · Cited by 660
Transport of dsRNA into Cells by the Transmembrane Protein SID-1
Feinberg, E. H., & Hunter, C. P. (2003) · Science · doi:10.1126/science.1087117 · Cited by 585
Development of the reproductive system of Caenorhabditis elegans
Hirsh, D., Oppenheim, D., & Klass, M. (1976) · Developmental Biology · doi:10.1016/0012-1606(76)90267-0 · Cited by 555
Wnt Signaling Polarizes an Early C. elegans Blastomere to Distinguish Endoderm from Mesoderm
Thorpe, C. J., Schlesinger, A., Carter, J. C., & Bowerman, B. (1997) · Cell · doi:10.1016/s0092-8674(00)80530-9 · Cited by 514
Inducible Antibacterial Defense System in C. elegans
Mallo, G. V., Kurz, C. L., Couillault, C., Pujol, N., Granjeaud, S., Kohara, Y., & Ewbank, J. J. (2002) · Current Biology · doi:10.1016/s0960-9822(02)00928-4 · Cited by 477
The C. elegans p38 MAPK pathway regulates nuclear localization of the transcription factor SKN-1 in oxidative stress response
Inoue, H., Hisamoto, N., An, J. H., Oliveira, R. P., Nishida, E., Blackwell, T. K., & Matsumoto, K. (2005) · Genes & Development · doi:10.1101/gad.1324805 · Cited by 442
Nuclear Hormone Receptor NHR-49 Controls Fat Consumption and Fatty Acid Composition in C. elegans
Gilst, M. R. V., Hadjivassiliou, H., Jolly, A., & Yamamoto, K. R. (2005) · PLoS Biology · doi:10.1371/journal.pbio.0030053 · Cited by 428
Transcriptional outputs of the Caenorhabditis elegans forkhead protein DAF‐16
McElwee, J., Bubb, K., & Thomas, J. H. (2003) · Aging Cell · doi:10.1046/j.1474-9728.2003.00043.x · Cited by 416
An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis
Yang, F., Vought, B. W., Satterlee, J. S., Walker, A. K., Jim Sun, Z.-Y., Watts, J. L., DeBeaumont, R., Mako Saito, R., Hyberts, S. G., Yang, S., et al. (2006) · Nature · doi:10.1038/nature04942 · Cited by 405
A Putative Catenin–Cadherin System Mediates Morphogenesis of the Caenorhabditis elegans Embryo
Costa, M., Raich, W., Agbunag, C., Leung, B., Hardin, J., & Priess, J. R. (1998) · The Journal of Cell Biology · doi:10.1083/jcb.141.1.297 · Cited by 396
Polyglutamine aggregates alter protein folding homeostasis in Caenorhabditis elegans
Satyal, S. H., Schmidt, E., Kitagawa, K., Sondheimer, N., Lindquist, S., Kramer, J. M., & Morimoto, R. I. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.100107297 · Cited by 371
PIE-1 is a bifunctional protein that regulates maternal and zygotic gene expression in the embryonic germ line of Caenorhabditis elegans
Tenenhaus, C., Subramaniam, K., Dunn, M. A., & Seydoux, G. (2001) · Genes & Development · doi:10.1101/gad.876201 · Cited by 357
Glycolipids as Receptors for Bacillus thuringiensis Crystal Toxin
Griffitts, J. S., Haslam, S. M., Yang, T., Garczynski, S. F., Mulloy, B., Morris, H., Cremer, P. S., Dell, A., Adang, M. J., & Aroian, R. V. (2005) · Science · doi:10.1126/science.1104444 · Cited by 352
Germ-Cell Loss Extends C. elegans Life Span through Regulation of DAF-16 by kri-1 and Lipophilic-Hormone Signaling
Berman, J. R., & Kenyon, C. (2006) · Cell · doi:10.1016/j.cell.2006.01.039 · Cited by 347
Tissue-specific synthesis of yolk proteins in Caenorhabditis elegans
Kimble, J., & Sharrock, W. J. (1983) · Developmental Biology · doi:10.1016/0012-1606(83)90322-6 · Cited by 329
The GATA-factor elt-2 is essential for formation of the Caenorhabditis elegans intestine
Fukushige, T., Hawkins, M. G., & McGhee, J. D. (1998) · Developmental Biology · doi:10.1016/s0012-1606(98)80006-7 · Cited by 326
Self-citation
Cell lineages of the embryo of the nematode Caenorhabditis elegans.
Deppe, U., Schierenberg, E., Cole, T., Krieg, C., Schmitt, D., Yoder, B., & von Ehrenstein, G. (1978) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.75.1.376 · Cited by 325
Mitogen-activated protein kinase pathways defend against bacterial pore-forming toxins
Huffman, D. L., Abrami, L., Sasik, R., Corbeil, J., van der Goot, F. G., & Aroian, R. V. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0404073101 · Cited by 316
pop-1 Encodes an HMG box protein required for the specification of a mesoderm precursor in Early C. elegans embryos
Lin, R., Thompson, S., & Priess, J. R. (1995) · Cell · doi:10.1016/0092-8674(95)90100-0 · Cited by 310
Goα and Diacylglycerol Kinase Negatively Regulate the Gqα Pathway in C. elegans
Miller, K. G., Emerson, M. D., & Rand, J. B. (1999) · Neuron · doi:10.1016/s0896-6273(00)80847-8 · Cited by 303
POP-1 and Anterior–Posterior Fate Decisions in C. elegans Embryos
Lin, R., Hill, R. J., & Priess, J. R. (1998) · Cell · doi:10.1016/s0092-8674(00)80917-4 · Cited by 282
Genetic Analysis of Lysosomal Trafficking in Caenorhabditis elegans
Hermann, G. J., Schroeder, L. K., Hieb, C. A., Kershner, A. M., Rabbitts, B. M., Fonarev, P., Grant, B. D., & Priess, J. R. (2005) · Molecular Biology of the Cell · doi:10.1091/mbc.e05-01-0060 · Cited by 279
Organogenesis of the Caenorhabditis elegans Intestine
Leung, B., Hermann, G. J., & Priess, J. R. (1999) · Developmental Biology · doi:10.1006/dbio.1999.9471 · Cited by 271
C. elegans
McKay, R. M., McKay, J. P., Avery, L., & Graff, J. M. (2003) · Developmental Cell · doi:10.1016/s1534-5807(02)00411-2 · Cited by 269
LET-23 Receptor Localization by the Cell Junction Protein LIN-7 during C. elegans Vulval Induction
Simske, J. S., Kaech, S. M., Harp, S. A., & Kim, S. K. (1996) · Cell · doi:10.1016/s0092-8674(00)81096-x · Cited by 265
Bacillus thuringiensis (Bt) Toxin Susceptibility and Isolation of Resistance Mutants in the Nematode Caenorhabditis elegans
Marroquin, L. D., Elyassnia, D., Griffitts, J. S., Feitelson, J. S., & Aroian, R. V. (2000) · Genetics · doi:10.1093/genetics/155.4.1693 · Cited by 262
Food transport in the C. elegans pharynx
Avery, L., & Shtonda, B. B. (2003) · Journal of Experimental Biology · doi:10.1242/jeb.00433 · Cited by 260
A Mediator subunit, MDT-15, integrates regulation of fatty acid metabolism by NHR-49-dependent and -independent pathways in C. elegans
Taubert, S., Van Gilst, M. R., Hansen, M., & Yamamoto, K. R. (2006) · Genes & Development · doi:10.1101/gad.1395406 · Cited by 259
The maternal gene skn-1 encodes a protein that is distributed unequally in early C. elegans embryos
Bowerman, B., Draper, B. W., Mello, C. C., & Priess, J. R. (1993) · Cell · doi:10.1016/0092-8674(93)80046-h · Cited by 251
Muscle organization in Caenorhabditis elegans: localization of proteins implicated in thin filament attachment and I-band organization.
Francis, G. R., & Waterston, R. H. (1985) · The Journal of cell biology · doi:10.1083/jcb.101.4.1532 · Cited by 248
Bt Toxin Resistance from Loss of a Putative Carbohydrate-Modifying Enzyme
Griffitts, J. S., Whitacre, J. L., Stevens, D. E., & Aroian, R. V. (2001) · Science · doi:10.1126/science.1062441 · Cited by 240
mab-3, a gene required for sex-specific yolk protein expression and a male-specific lineage in C. elegans
Shen, M. M., & Hodgkin, J. (1988) · Cell · doi:10.1016/0092-8674(88)90117-1 · Cited by 237
Regulation of the Caenorhabditis elegans oxidative stress defense protein SKN-1 by glycogen synthase kinase-3
An, J. H., Vranas, K., Lucke, M., Inoue, H., Hisamoto, N., Matsumoto, K., & Blackwell, T. K. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0508105102 · Cited by 235
Evolution of the innate immune system: the worm perspective
Schulenburg, H., Léopold Kurz, C., & Ewbank, J. J. (2004) · Immunological Reviews · doi:10.1111/j.0105-2896.2004.0125.x · Cited by 230
Spatial and Temporal Controls Target pal-1 Blastomere-Specification Activity to a Single Blastomere Lineage in C. elegans Embryos
Hunter, C. P., & Kenyon, C. (1996) · Cell · doi:10.1016/s0092-8674(00)81340-9 · Cited by 224
The Inositol Trisphosphate Receptor Regulates a 50-Second Behavioral Rhythm in C. elegans
Dal Santo, P., Logan, M. A., Chisholm, A. D., & Jorgensen, E. M. (1999) · Cell · doi:10.1016/s0092-8674(00)81510-x · Cited by 222
Induction of gut in Caenorhabditis elegans embryos
Goldstein, B. (1992) · Nature · doi:10.1038/357255a0 · Cited by 221
The Caenorhabditis elegans unc-64 Locus Encodes a Syntaxin That Interacts Genetically with Synaptobrevin
Saifee, O., Wei, L., & Nonet, M. L. (1998) · Molecular Biology of the Cell · doi:10.1091/mbc.9.6.1235 · Cited by 220
Monomethyl Branched-Chain Fatty Acids Play an Essential Role in Caenorhabditis elegans Development
Kniazeva, M., Crawford, Q. T., Seiber, M., Wang, C.-Y., & Han, M. (2004) · PLoS Biology · doi:10.1371/journal.pbio.0020257 · Cited by 219
Homologues of the human multidrug resistance genes MRP and MDR contribute to heavy metal resistance in the soil nematode Caenorhabditis elegans.
Broeks, A., Gerrard, B., Allikmets, R., Dean, M., & Plasterk, R. H. (1996) · The EMBO Journal · doi:10.1002/j.1460-2075.1996.tb01001.x · Cited by 219
A Caenorhabditis elegans model of insulin resistance: Altered macronutrient storage and dauer formation in an OGT-1 knockout
Hanover, J. A., Forsythe, M. E., Hennessey, P. T., Brodigan, T. M., Love, D. C., Ashwell, G., & Krause, M. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0408771102 · Cited by 218
end-1 encodes an apparent GATA factor that specifies the endoderm precursor in Caenorhabditis elegans embryos
Zhu, J., Hill, R. J., Heid, P. J., Fukuyama, M., Sugimoto, A., Priess, J. R., & Rothman, J. H. (1997) · Genes & Development · doi:10.1101/gad.11.21.2883 · Cited by 216
pha-4, an HNF-3 homolog, specifies pharyngeal organ identity in Caenorhabditis elegans
Horner, M. A., Quintin, S., Domeier, M. E., Kimble, J., Labouesse, M., & Mango, S. E. (1998) · Genes & Development · doi:10.1101/gad.12.13.1947 · Cited by 209
Hemicentin, a conserved extracellular member of the immunoglobulin superfamily, organizes epithelial and other cell attachments into oriented line- shaped junctions
Vogel, B. E., & Hedgecock, E. M. (2001) · Development · doi:10.1242/dev.128.6.883 · Cited by 207
Developmental regulation of a cyclin-dependent kinase inhibitor controls postembryonic cell cycle progression in Caenorhabditis elegans
Hong, Y., Roy, R., & Ambros, V. (1998) · Development · doi:10.1242/dev.125.18.3585 · Cited by 204
RAB-10 Is Required for Endocytic Recycling in the Caenorhabditis elegans Intestine
Chen, C. C.-H., Schweinsberg, P. J., Vashist, S., Mareiniss, D. P., Lambie, E. J., & Grant, B. D. (2006) · Molecular Biology of the Cell · doi:10.1091/mbc.e05-08-0787 · Cited by 202
Polyploid tissues in the nematode Caenorhabditis elegans
Hedgecock, E. M., & White, J. G. (1985) · Developmental Biology · doi:10.1016/0012-1606(85)90381-1 · Cited by 199
The autofluorescent “lipofuscin granules” in the intestinal cells of Caenorhabditis elegans are secondary lysosomes
Clokey, G. V., & Jacobson, L. A. (1986) · Mechanisms of Ageing and Development · doi:10.1016/0047-6374(86)90068-0 · Cited by 198
Making Worm Guts: The Gene Regulatory Network of the Caenorhabditis elegans Endoderm
Maduro, M. F., & Rothman, J. H. (2002) · Developmental Biology · doi:10.1006/dbio.2002.0655 · Cited by 198
Hormonal Control of C. elegans Dauer Formation and Life Span by a Rieske-like Oxygenase
Rottiers, V., Motola, D. L., Gerisch, B., Cummins, C. L., Nishiwaki, K., Mangelsdorf, D. J., & Antebi, A. (2006) · Developmental Cell · doi:10.1016/j.devcel.2006.02.008 · Cited by 196
Polygenic control of Caenorhabditis elegans fat storage
Mak, H. Y., Nelson, L. S., Basson, M., Johnson, C. D., & Ruvkun, G. (2006) · Nature Genetics · doi:10.1038/ng1739 · Cited by 193
LET-413 is a basolateral protein required for the assembly of adherens junctions in Caenorhabditis elegans
Legouis, R., Gansmuller, A., Sookhareea, S., Bosher, J. M., Baillie, D. L., & Labouesse, M. (2000) · Nature Cell Biology · doi:10.1038/35017046 · Cited by 189
DNA synthesis and the control of embryonic gene expression in C. elegans
Edgar, L. G., & McGhee, J. D. (1988) · Cell · doi:10.1016/0092-8674(88)90575-2 · Cited by 188
Self-citation
The pha-4 gene is required to generate the pharyngeal primordium of Caenorhabditis elegans
Mango, S. E., Lambie, E. J., & Kimble, J. (1994) · Development · doi:10.1242/dev.120.10.3019 · Cited by 187
Restriction of Mesendoderm to a Single Blastomere by the Combined Action of SKN-1 and a GSK-3β Homolog Is Mediated by MED-1 and -2 in C. elegans
Maduro, M. F., Meneghini, M. D., Bowerman, B., Broitman-Maduro, G., & Rothman, J. H. (2001) · Molecular Cell · doi:10.1016/s1097-2765(01)00195-2 · Cited by 185
NUC-1, a Caenorhabditis elegans DNase II homolog, functions in an intermediate step of DNA degradation during apoptosis
Wu, Y.-C., Stanfield, G. M., & Horvitz, H. R. (2000) · Genes & Development · doi:10.1101/gad.14.5.536 · Cited by 179
Deletion of the Intestinal Peptide Transporter Affects Insulin and TOR Signaling in Caenorhabditis elegans
Meissner, B., Boll, M., Daniel, H., & Baumeister, R. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m403415200 · Cited by 178
unc-83 encodes a novel component of the nuclear envelope and is essential for proper nuclear migration
Starr, D. A., Hermann, G. J., Malone, C. J., Fixsen, W., Priess, J. R., Horvitz, H. R., & Han, M. (2001) · Development · doi:10.1242/dev.128.24.5039 · Cited by 175
The ELT-2 GATA-factor and the global regulation of transcription in the C. elegans intestine
McGhee, J. D., Sleumer, M. C., Bilenky, M., Wong, K., McKay, S. J., Goszczynski, B., Tian, H., Krich, N. D., Khattra, J., Holt, R. A., et al. (2007) · Developmental Biology · doi:10.1016/j.ydbio.2006.10.024 · Cited by 172
Self-citation
Oscillatory Ca2+ Signaling in the Isolated Caenorhabditis elegans Intestine
Espelt, M. V., Estevez, A. Y., Yin, X., & Strange, K. (2005) · The Journal of General Physiology · doi:10.1085/jgp.200509355 · Cited by 172
Caenorhabditis elegans RME-6 is a novel regulator of RAB-5 at the clathrin-coated pit
Sato, M., Sato, K., Fonarev, P., Huang, C.-J., Liou, W., & Grant, B. D. (2005) · Nature Cell Biology · doi:10.1038/ncb1261 · Cited by 170
Evidence from reversal of handedness in C. elegans embryos for early cell interactions determining cell fates
Wood, W. B. (1991) · Nature · doi:10.1038/349536a0 · Cited by 169
C.elegans Metallothioneins: New Insights into the Phenotypic Effects of Cadmium Toxicosis
Swain, S. C., Keusekotten, K., Baumeister, R., & Stürzenbaum, S. R. (2004) · Journal of Molecular Biology · doi:10.1016/j.jmb.2004.06.050 · Cited by 168
Dietary restriction in C. elegans: From rate-of-living effects to nutrient sensing pathways
Walker, G., Houthoofd, K., Vanfleteren, J. R., & Gems, D. (2005) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2005.03.014 · Cited by 168
Zonula adherens formation in Caenorhabditis elegans requires dlg-1, the homologue of the Drosophila gene discs large
Bossinger, O., Klebes, A., Segbert, C., Theres, C., & Knust, E. (2001) · Developmental Biology · doi:10.1006/dbio.2000.0113 · Cited by 161
A Systematic Gene Expression Screen of Caenorhabditis elegans Cytochrome P450 Genes Reveals CYP35 as Strongly Xenobiotic Inducible
Menzel, R., Bogaert, T., & Achazi, R. (2001) · Archives of Biochemistry and Biophysics · doi:10.1006/abbi.2001.2568 · Cited by 161
Lumen Morphogenesis in C. elegans Requires the Membrane-Cytoskeleton Linker erm-1
Göbel, V., Barrett, P. L., Hall, D. H., & Fleming, J. T. (2004) · Developmental Cell · doi:10.1016/j.devcel.2004.05.018 · Cited by 159
Reprogramming of early embryonic blastomeres into endodermal progenitors by a Caenorhabditis elegans GATA factor
Zhu, J., Fukushige, T., McGhee, J. D., & Rothman, J. H. (1998) · Genes & Development · doi:10.1101/gad.12.24.3809 · Cited by 159
Self-citation
Laminin α subunits and their role in C. elegans development
Huang, C., Hall, D. H., Hedgecock, E. M., Kao, G., Karantza, V., Vogel, B. E., Hutter, H., Chisholm, A. D., Yurchenco, P. D., & Wadsworth, W. G. (2003) · Development · doi:10.1242/dev.00481 · Cited by 158
Targeting of Rough Endoplasmic Reticulum Membrane Proteins and Ribosomes in Invertebrate Neurons
Rolls, M. M., Hall, D. H., Victor, M., Stelzer, E. H. K., & Rapoport, T. A. (2002) · Molecular Biology of the Cell · doi:10.1091/mbc.01-10-0514 · Cited by 156
Transcriptional targets of DAF-16 insulin signaling pathway protect C. elegans from extreme hypertonic stress
Lamitina, S. T., & Strange, K. B. (2004) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00451.2004 · Cited by 155
Parental effects and phenotypic characterization of mutations that affect early development in Caenorhabditis elegans
Wood, W. B., Hecht, R. M., Carr, S., Vanderslice, R. W., Wolf, N., & Hirsh, D. (1980) · Developmental Biology · doi:10.1016/0012-1606(80)90445-5 · Cited by 154
Basolateral targeting by leucine‐rich repeat domains in epithelial cells
Legouis, R., Jaulin‐Bastard, F., Schott, S., Navarro, C., Borg, J., & Labouesse, M. (2003) · The EMBO Reports · doi:10.1038/sj.embor.7400006 · Cited by 153
Mutants of Caenorhabditis elegans that form dauer-like larvae
Albert, P. S., & Riddle, D. L. (1988) · Developmental Biology · doi:10.1016/0012-1606(88)90138-8 · Cited by 153
C. elegans Dynamin Mediates the Signaling of Phagocytic Receptor CED-1 for the Engulfment and Degradation of Apoptotic Cells
Yu, X., Odera, S. L., Chuang, C.-H., Lü, N., & Zhou, Z. (2006) · Developmental Cell · doi:10.1016/j.devcel.2006.04.007 · Cited by 148
Explosive Lineage-Specific Expansion of the Orphan Nuclear Receptor HNF4 in Nematodes
Robinson‐Rechavi, M., Maina, C. V., Gissendanner, C. R., Laudet, V., & Sluder, A. E. (2005) · Journal of Molecular Evolution · doi:10.1007/s00239-004-0175-8 · Cited by 146
Phosphorylation by the β-Catenin/MAPK Complex Promotes 14-3-3-Mediated Nuclear Export of TCF/POP-1 in Signal-Responsive Cells in C. elegans
Lo, M.-C., Gay, F., Odom, R., Shi, Y., & Lin, R. (2004) · Cell · doi:10.1016/s0092-8674(04)00203-x · Cited by 138
Calreticulin, a Calcium-binding Molecular Chaperone, Is Required for Stress Response and Fertility inCaenorhabditis elegans
Park, B.-J., Lee, D., Yu, J.-R., Jung, S., Choi, K.-Y., Lee, J., Lee, J., Kim, Y. S., Lee, J. I., Kwon, J. Y., et al. (2001) · Molecular Biology of the Cell · doi:10.1091/mbc.12.9.2835 · Cited by 138
Type IV Collagen Is Detectable in Most, but Not All, Basement Membranes of Caenorhabditis elegans and Assembles on Tissues That Do Not Express It
Graham, P. L., Johnson, J. J., Wang, S., Sibley, M. H., Gupta, M. C., & Kramer, J. M. (1997) · The Journal of Cell Biology · doi:10.1083/jcb.137.5.1171 · Cited by 137
Resistance to a Bacterial Toxin Is Mediated by Removal of a Conserved Glycosylation Pathway Required for Toxin-Host Interactions
Griffitts, J. S., Huffman, D. L., Whitacre, J. L., Barrows, B., Marroquin, L. D., Müller, R., Brown, J. R., Hennet, T., Esko, J. D., & Aroian, R. V. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m308142200 · Cited by 131
Four Subunit a Isoforms ofCaenorhabditis elegans Vacuolar H+-ATPase
Oka, T., Toyomura, T., Honjo, K., Wada, Y., & Futai, M. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m101652200 · Cited by 130
Chromatin regulation and sumoylation in the inhibition of Ras‐induced vulval development in Caenorhabditis elegans
Poulin, G. B., Yan, D., Fraser, A. G., Hopper, N. A., & Ahringer, J. (2005) · The EMBO Journal · doi:10.1038/sj.emboj.7600726 · Cited by 130
Chromosomal clustering and GATA transcriptional regulation of intestine-expressed genes inC. elegans
Pauli, F., Liu, Y. I., Kim, Y. A., Chen, P.-J., & Kim, S. K. (2005) · Development · doi:10.1242/dev.02185 · Cited by 127
A Reduction in Intestinal Cell pH Due to Loss of the Caenorhabditis elegans Na+/H+ Exchanger NHX-2 Increases Life Span
Nehrke, K. W. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m307351200 · Cited by 125
The homeodomain protein PAL-1 specifies a lineage-specific regulatory network in theC. elegansembryo
Baugh, L. R., Hill, A. A. V., Claggett, J. M., Hill‐Harfe, K., Wen, J. C., Slonim, D. K., Brown, E. L., & Hunter, C. P. (2005) · Development · doi:10.1242/dev.01782 · Cited by 121
A novel actin barbed-end-capping activity in EPS-8 regulates apical morphogenesis in intestinal cells of Caenorhabditis elegans
Croce, A., Cassata, G., Disanza, A., Gagliani, M. C., Tacchetti, C., Malabarba, M. G., Carlier, M., Scita, G., Baumeister, R., & Fiore, P. P. D. (2004) · Nature Cell Biology · doi:10.1038/ncb1198 · Cited by 119
Fluoxetine-Resistant Mutants in C. elegans Define a Novel Family of Transmembrane Proteins
Choy, R. K. M., & Thomas, J. H. (1999) · Molecular Cell · doi:10.1016/s1097-2765(00)80362-7 · Cited by 117
C. elegans TCF protein, POP-1, converts from repressor to activator as a result of Wnt-induced lowering of nuclear levels
Shetty, P. V., Lo, M., Robertson, S. M., & Lin, R. (2005) · Developmental Biology · doi:10.1016/j.ydbio.2005.07.008 · Cited by 117
The C. elegans ezrin-radixin-moesin protein ERM-1 is necessary for apical junction remodelling and tubulogenesis in the intestine
van Fürden, D., Johnson, K., Segbert, C., & Bossinger, O. (2004) · Developmental Biology · doi:10.1016/j.ydbio.2004.05.012 · Cited by 116
Essential roles for four cytoplasmic intermediate filament proteins in Caenorhabditis elegans development
Karabinoš, A., Schmidt, H., Harborth, J., Schnabel, R., & Weber, K. K. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.121169998 · Cited by 114
Direct visualization of the elt-2 gut-specific GATA factor binding to a target promoter inside the living Caenorhabditis elegans embryo
Fukushige, T., Hendzel, M. J., Bazett‐Jones, D. P., & McGhee, J. D. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.21.11883 · Cited by 110
Self-citation
Genetic redundancy in endoderm specification within the genus Caenorhabditis
Maduro, M., Hill, R. J., Heid, P. J., Newman-Smith, E. D., Zhu, J., Priess, J. R., & Rothman, J. H. (2005) · Developmental Biology · doi:10.1016/j.ydbio.2005.05.016 · Cited by 109
Diverse Chromatin Remodeling Genes Antagonize the Rb-Involved SynMuv Pathways in C. elegans
Cui, M., Kim, E. B., & Han, M. (2006) · PLoS Genetics · doi:10.1371/journal.pgen.0020074 · Cited by 108
The conserved nuclear receptor Ftz‐F1 is required for embryogenesis, moulting and reproduction in Caenorhabditis elegans
Asahina, M., Ishihara, T., Jindra, M., Kohara, Y., Katsura, I., & Hirose, S. (2000) · Genes to Cells · doi:10.1046/j.1365-2443.2000.00361.x · Cited by 107
elt-1 , an Embryonically Expressed Caenorhabditis elegans Gene Homologous to the GATA Transcription Factor Family
Spieth, J., Shim, Y., Lea, K., Conrad, R. C., & Blumenthal, T. (1991) · Molecular and Cellular Biology · doi:10.1128/mcb.11.9.4651 · Cited by 101
The REF-1 Family of bHLH Transcription Factors Pattern C. elegans Embryos through Notch-Dependent and Notch-Independent Pathways
Neves, A., & Priess, J. R. (2005) · Developmental Cell · doi:10.1016/j.devcel.2005.03.012 · Cited by 99
The apical disposition of the Caenorhabditis elegans intestinal terminal web is maintained by LET-413
Bossinger, O., Fukushige, T., Claeys, M., Borgonie, G., & McGhee, J. D. (2004) · Developmental Biology · doi:10.1016/j.ydbio.2004.01.003 · Cited by 98
Self-citation
Functional tests of enhancer conservation between distantly related species
Ruvinsky, I., & Ruvkun, G. (2003) · Development · doi:10.1242/dev.00711 · Cited by 97
Identification and molecular-genetic characterization of a LAMP/CD68-like protein from Caenorhabditis elegans
Kostich, M. S., Fire, A. Z., & Fambrough, D. M. (2000) · Journal of Cell Science · doi:10.1242/jcs.113.14.2595 · Cited by 97
Regulation of Metallothionein Gene Transcription
Moilanen, L. H., Fukushige, T., & Freedman, J. H. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.42.29655 · Cited by 96
Nidogen Is Nonessential and Not Required for Normal Type IV Collagen Localization inCaenorhabditis elegans
Kang, S. H., & Kramer, J. M. (2000) · Molecular Biology of the Cell · doi:10.1091/mbc.11.11.3911 · Cited by 96
The Wnt effector POP-1 and the PAL-1/Caudal homeoprotein collaborate with SKN-1 to activate C. elegans endoderm development
Maduro, M., Kasmir, J. J., Zhu, J., & Rothman, J. H. (2005) · Developmental Biology · doi:10.1016/j.ydbio.2005.06.022 · Cited by 93
What keeps C. elegans regular: the genetics of defecation
Branicky, R. S., & Hekimi, S. (2006) · Trends in Genetics · doi:10.1016/j.tig.2006.08.006 · Cited by 93
Biochemical Discrimination between Luminal and Abluminal Enzyme and Transport Activities of the Blood-Brain Barrier
del Pino, M. M. S., Hawkins, R. A., & Peterson, D. R. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.25.14907 · Cited by 92
Relevance of NAC-2, an Na+-coupled citrate transporter, to life span, body size and fat content in Caenorhabditis elegans
Fei, Y.-J., Liu, J.-C., Inoue, K., Zhuang, L., Miyake, K., Miyauchi, S., & Ganapathy, V. (2004) · Biochemical Journal · doi:10.1042/bj20031807 · Cited by 89
elt-2, a Second GATA Factor from the Nematode Caenorhabditis elegans
Hawkins, M. G., & McGhee, J. D. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.24.14666 · Cited by 87
Self-citation
Deciphering Endocytosis in Caenorhabditis elegans
Fares, H., & Grant, B. D. (2002) · Traffic · doi:10.1034/j.1600-0854.2002.30103.x · Cited by 86
Dietary manipulation implicates lipid signaling in the regulation of germ cell maintenance in C. elegans
Watts, J. L., & Browse, J. (2006) · Developmental Biology · doi:10.1016/j.ydbio.2006.01.013 · Cited by 86
Left-right asymmetry in C. elegans intestine organogenesis involves a LIN-12/Notch signaling pathway
Hermann, G. J., Leung, B., & Priess, J. R. (2000) · Development · doi:10.1242/dev.127.16.3429 · Cited by 85
A Gut-to-Pharynx/Tail Switch in Embryonic Expression of the Caenorhabditis elegans ges-1 Gene Centers on Two GATA Sequences
Egan, C., Chung, M. A., Allen, F. L., Heschl, M. F. P., Buskirk, C. V., & McGhee, J. D. (1995) · Developmental Biology · doi:10.1006/dbio.1995.1225 · Cited by 84
Self-citation
C. elegans cell cycles: invariance and stem cell divisions
Kipreos, E. T. (2005) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1738 · Cited by 84
The C. elegans lethal gut-obstructed gob-1 gene is trehalose-6-phosphate phosphatase
Kormish, J. D., & McGhee, J. D. (2005) · Developmental Biology · doi:10.1016/j.ydbio.2005.08.027 · Cited by 80
Self-citation
CeVPS‐27 is an Endosomal Protein Required for the Molting and the Endocytic Trafficking of the Low‐Density Lipoprotein Receptor‐Related Protein 1 in Caenorhabditis elegans
Roudier, N., Lefebvre, C., & Legouis, R. (2005) · Traffic · doi:10.1111/j.1600-0854.2005.00309.x · Cited by 79
Eight genes and alternative RNA processing pathways generate an unexpectedly large diversity of cytoplasmic intermediate filament proteins in the nematode Caenorhabditis elegans.
DODEMONT, H. J., Riemer, D., Ledger, N., & Weber, K. (1994) · The EMBO Journal · doi:10.1002/j.1460-2075.1994.tb06553.x · Cited by 78
The NHX Family of Na+-H+ Exchangers in Caenorhabditis elegans
Nehrke, K. W., & Melvin, J. E. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m203200200 · Cited by 78
Amoebapore homologs of Caenorhabditis elegans
Bányai, L., & Patthy, L. (1998) · Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology · doi:10.1016/s0167-4838(98)00237-4 · Cited by 77
Zygotic Expression of the caudal Homolog pal-1 Is Required for Posterior Patterning in Caenorhabditis elegans Embryogenesis
Edgar, L. G., Carr, S., Wang, H., & Wood, W. B. (2001) · Developmental Biology · doi:10.1006/dbio.2000.9977 · Cited by 74
Genetic Analysis of the Myotubularin Family of Phosphatases in Caenorhabditis elegans
Xue, Y., Fares, H., Grant, B. D., Li, Z., Rose, A. M., Clark, S. G., & Skolnik, E. Y. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m303259200 · Cited by 73
Afork head/HNF-3 Homolog Expressed in the Pharynx and Intestine of theCaenorhabditis elegansEmbryo
Azzaria, M., Goszczynski, B., Chung, M. A., Kalb, J. M., & McGhee, J. D. (1996) · Developmental Biology · doi:10.1006/dbio.1996.0219 · Cited by 72
Self-citation
Molecular Characterization of a Novel, Cadmium-inducible Gene from the Nematode Caenorhabditis elegans
Liao, V. H., Dong, J., & Freedman, J. H. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m206740200 · Cited by 72
Expression of Three Caenorhabditis elegans N-Acetylglucosaminyltransferase I Genes during Development
Chen, S., Zhou, S., Sarkar, M., Spence, A. M., & Schachter, H. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.1.288 · Cited by 72
Multiple Skp1-Related Proteins in Caenorhabditis elegans
Yamanaka, A., Yada, M., Imaki, H., Koga, M., Ohshima, Y., & Nakayama, K. I. (2002) · Current Biology · doi:10.1016/s0960-9822(02)00657-7 · Cited by 72
Molecular and functional analysis of apical junction formation in the gut epithelium of Caenorhabditis elegans
Segbert, C., Johnson, K., Theres, C., van Fürden, D., & Bossinger, O. (2004) · Developmental Biology · doi:10.1016/j.ydbio.2003.10.019 · Cited by 72
Aspartic Proteases from the Nematode Caenorhabditis elegans
Tcherepanova, I. Y., Bhattacharyya, L., Rubin, C. S., & Freedman, J. H. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m000956200 · Cited by 65
The role of the laminin β subunit in laminin heterotrimer assembly and basement membrane function and development in C. elegans
Kao, G., Huang, C.-C., Hedgecock, E. M., Hall, D. H., & Wadsworth, W. G. (2005) · Developmental Biology · doi:10.1016/j.ydbio.2005.11.026 · Cited by 65
Sphingosine Phosphate Lyase Expression Is Essential for Normal Development in Caenorhabditis elegans
Mendel, J., Heinecke, K., Fyrst, H., & Saba, J. D. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m302857200 · Cited by 65
The expression of two P‐glycoprotein (pgp) genes in transgenic Caenorhabditis elegans is confined to intestinal cells.
Lincke, C. R., Broeks, A., The, I., Plasterk, R. H. A., & Borst, P. (1993) · The EMBO Journal · doi:10.1002/j.1460-2075.1993.tb05806.x · Cited by 65
The Zinc Finger Protein DIE-1 Is Required for Late Events during Epithelial Cell Rearrangement in C. elegans
Heid, P. J., Raich, W. B., Smith, R., Mohler, W. A., Simokat, K., Gendreau, S. B., Rothman, J. H., & Hardin, J. D. (2001) · Developmental Biology · doi:10.1006/dbio.2001.0315 · Cited by 64
The let-268 Locus of Caenorhabditis elegans Encodes a Procollagen Lysyl Hydroxylase That Is Essential for Type IV Collagen Secretion
Norman, K. R., & Moerman, D. G. (2000) · Developmental Biology · doi:10.1006/dbio.2000.9897 · Cited by 64
Maternal deployment of the embryonic SKN-1 → MED-1,2 cell specification pathway in C. elegans
Maduro, M., Broitman-Maduro, G., Mengarelli, I., & Rothman, J. H. (2006) · Developmental Biology · doi:10.1016/j.ydbio.2006.08.029 · Cited by 63
Transcriptional Regulation and Life-span Modulation of Cytosolic Aconitase and Ferritin Genes in C.elegans
Kim, Y., Cho, J. H., Yoo, O. J., & Ahnn, J. (2004) · Journal of Molecular Biology · doi:10.1016/j.jmb.2004.07.036 · Cited by 63
Requirement of V-ATPase for Ovulation and Embryogenesis inCaenorhabditis elegans
Oka, T., & Futai, M. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m002756200 · Cited by 63
Differential regulation of TRPM channels governs electrolyte homeostasis in the C. elegans intestine
Teramoto, T., Lambie, E. J., & Iwasaki, K. (2005) · Cell Metabolism · doi:10.1016/j.cmet.2005.04.007 · Cited by 63
The Forkhead transcription factor UNC-130 is required for the graded spatial expression of the UNC-129 TGF-β guidance factor in C. elegansPreprint
Nash, B., Colavita, A., Zheng, H., Roy, P. J., & Culotti, J. G. (2000) · Genes & Development · doi:10.1101/gad.831500 · Cited by 63
Polycomb Group Regulation of Hox Gene Expression in C. elegans
Ross, J. M., & Zarkower, D. A. (2003) · Developmental Cell · doi:10.1016/s1534-5807(03)00135-7 · Cited by 62
An ion channel of the degenerin/epithelial sodium channel superfamily controls the defecation rhythm in Caenorhabditis elegans
Takeuchi, M., Kawakami, M., Ishihara, T., Amano, T., Kondo, K., & Katsura, I. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.20.11775 · Cited by 62
Using Caenorhabditis elegans for functional analysis of genes of parasitic nematodes
Britton, C., & Murray, L. (2006) · International Journal for Parasitology · doi:10.1016/j.ijpara.2006.02.010 · Cited by 61
Cell Autonomous Expression of Perlecan and Plasticity of Cell Shape in Embryonic Muscle ofCaenorhabditis elegans
Moerman, D. G., Hutter, H., Mullen, G. P., & Schnabel, R. (1996) · Developmental Biology · doi:10.1006/dbio.1996.0019 · Cited by 59
The Noncanonical Binding Site of the MED-1 GATA Factor Defines Differentially Regulated Target Genes in the C. elegans Mesendoderm
Broitman-Maduro, G., Maduro, M., & Rothman, J. H. (2005) · Developmental Cell · doi:10.1016/j.devcel.2005.01.014 · Cited by 58
Regulation of the Caenorhabditis elegans gut cysteine protease gene cpr-1: requirement for GATA motifs
Britton, C., McKerrow, J. H., & Johnstone, I. L. (1998) · Journal of Molecular Biology · doi:10.1006/jmbi.1998.2093 · Cited by 57
In Vivo and in Vitro Evidence that the Four Essential Intermediate Filament (IF) Proteins A1, A2, A3 and B1 of the Nematode Caenorhabditis elegans Form an Obligate Heteropolymeric IF System
Karabinoš, A., Schulze, E., Schünemann, J., Parry, D. A. D., & Weber, K. K. (2003) · Journal of Molecular Biology · doi:10.1016/j.jmb.2003.08.041 · Cited by 54
Essential embryonic roles of the CKI-1 cyclin-dependent kinase inhibitor in cell-cycle exit and morphogenesis in C. elegans
Fukuyama, M., Gendreau, S. B., Derry, W. B., & Rothman, J. H. (2003) · Developmental Biology · doi:10.1016/s0012-1606(03)00239-2 · Cited by 53
Organ-specific cell division abnormalities caused by mutation in a general cell cycle regulator inC. elegans
Kostić, I., & Roy, R. (2002) · Development · doi:10.1242/dev.129.9.2155 · Cited by 52
Structure and Function Analysis of LIN-14, a Temporal Regulator of Postembryonic Developmental Events in Caenorhabditis elegans
Yang, H. Y., Lee, R. C., & Ambros, V. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.6.2285-2295.2000 · Cited by 52
Fluoxetine-Resistance Genes inCaenorhabditis elegansFunction in the Intestine and May Act in Drug Transport
Choy, R. K. M., Kemner, J. M., & Thomas, J. H. (2005) · Genetics · doi:10.1534/genetics.103.024869 · Cited by 52
The Caenorhabditis elegans Gene lin-26 Can Trigger Epithelial Differentiation without Conferring Tissue Specificity
Quintin, S., Michaux, G., McMahon, L., Gansmüller, A., & Labouesse, M. (2001) · Developmental Biology · doi:10.1006/dbio.2001.0294 · Cited by 52
Thioredoxin is related to life span regulation and oxidative stress response inCaenorhabditis elegans
Jee, C., Vanoaica, L., Lee, J., Park, B. J., & Ahnn, J. (2005) · Genes to Cells · doi:10.1111/j.1365-2443.2005.00913.x · Cited by 51
The Evolutionary Duplication and Probable Demise of an Endodermal GATA Factor inCaenorhabditis elegans
Fukushige, T., Goszczynski, B., Tian, H. S., & McGhee, J. D. (2003) · Genetics · doi:10.1093/genetics/165.2.575 · Cited by 50
Self-citation
Oncogenic potential of a C.elegans cdc25 gene is demonstrated by a gain‐of‐function allele
Clucas, C., Cabello, J., Büssing, I., Schnabel, R., & Johnstone, I. L. (2002) · The EMBO Journal · doi:10.1093/emboj/21.4.665 · Cited by 49
The caenorhabditis elegans innexin INX-3 is localized to gap junctions and is essential for embryonic development
Starich, T. A., Miller, A. E., Nguyen, R. L., Hall, D. H., & Shaw, J. E. (2003) · Developmental Biology · doi:10.1016/s0012-1606(02)00116-1 · Cited by 49
Modeling human peroxisome biogenesis disorders in the nematodeCaenorhabditis elegans
Thieringer, H. A., Moellers, B., Dodt, G., Kunau, W., & Driscoll, M. (2003) · Journal of Cell Science · doi:10.1242/jcs.00380 · Cited by 47
ATP-binding Cassette Transporters Are Required for Efficient RNA Interference inCaenorhabditis elegans
Sundaram, P., Echalier, B., Wang, H., Hull, D. R., & Timmons, L. (2006) · Molecular Biology of the Cell · doi:10.1091/mbc.e06-03-0192 · Cited by 47
A regulatory network of T-box genes and theeven-skippedhomologuevab-7controls patterning and morphogenesis inC. elegans
Pocock, R., Ahringer, J., Mitsch, M. J., Maxwell, S., & Woollard, A. C. S. (2004) · Development · doi:10.1242/dev.01110 · Cited by 46
Identification of Store-independent and Store-operated Ca2+ Conductances in Caenorhabditis elegans Intestinal Epithelial Cells
Estevez, A. Y., Roberts, R. K., & Strange, K. B. (2003) · The Journal of General Physiology · doi:10.1085/jgp.200308804 · Cited by 43
Anterior-posterior patterning within the Caenorhabditis elegans endoderm
Schroeder, D. F., & McGhee, J. D. (1998) · Development · doi:10.1242/dev.125.24.4877 · Cited by 42
Self-citation
Most genes encoding cytoplasmic intermediate filament (IF) proteins of the nematode Caenorhabditis elegans are required in late embryogenesis
Karabinoš, A., Schünemann, J., & Weber, K. K. (2004) · European Journal of Cell Biology · doi:10.1078/0171-9335-00407 · Cited by 40
Aspects of the fine structure of the dauer larva of the nematode Caenorhabditis elegans
Popham, J. D., & Webster, J. M. (1979) · Canadian Journal of Zoology · doi:10.1139/z79-098 · Cited by 38
Structure, Expression, and Properties of an Atypical Protein Kinase C (PKC3) from Caenorhabditis elegans
Wu, S.-L., Staudinger, J. L., Olson, E. N., & Rubin, C. S. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.2.1130 · Cited by 37
The use of fluorescent marker dyes for studying intercellular communication in nematode embryos
Bossinger, O., & Schierenberg, E. (1996) · The International Journal of Developmental Biology · doi:10.1387/ijdb.8735958 · Cited by 37
Cell-cycle control in Caenorhabditis elegans: how the worm moves from G1 to S
Koreth, J., & van den Heuvel, S. (2005) · Oncogene · doi:10.1038/sj.onc.1208607 · Cited by 36
The dietary restriction effect in C. elegans and humans: is the worm a one-millimeter human?
Braeckman, B. P., Demetrius, L., & Vanfleteren, J. R. (2006) · Biogerontology · doi:10.1007/s10522-006-9003-4 · Cited by 36
Cyclin-dependent kinases in C. elegans.
Boxem, M. (2006) · Cell Division · doi:10.1186/1747-1028-1-6 · Cited by 36
Proteases of the nematode Caenorhabditis elegans
Sarkis, G. J., Kurpiewski, M. R., Ashcom, J. D., et al. (1988) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(88)90106-3 · Cited by 35
Molecular Cloning and Characterization of a Novel α1,2-Fucosyltransferase (CE2FT-1) from Caenorhabditis elegans
Zheng, Q., van Die, I., & Cummings, R. D. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m207487200 · Cited by 35
Identification and characterization of a family of Caenorhabditis elegans genes that is homologous to the cadmium-responsive gene cdr-1
Dong, J., Song, M. O., & Freedman, J. H. (2004) · Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression · doi:10.1016/j.bbaexp.2004.11.007 · Cited by 34
The abts and sulp families of anion transporters from Caenorhabditis elegans
Sherman, T., Chernova, M. N., Clark, J. S., Jiang, L., Alper, S. L., & Nehrke, K. W. (2005) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00071.2005 · Cited by 34
Functional expression and characterization of the cytoplasmic aminopeptidase P ofCaenorhabditis elegans
Laurent, V., Brooks, D. R., Coates, D., & Isaac, R. E. (2001) · European Journal of Biochemistry · doi:10.1046/j.0014-2956.2001.02483.x · Cited by 33
Reevaluation of the Role of the med-1 and med-2 Genes in Specifying the Caenorhabditis elegans Endoderm
Goszczynski, B., & McGhee, J. D. (2005) · Genetics · doi:10.1534/genetics.105.044909 · Cited by 33
Self-citation
Expression profiles of the essential intermediate filament (IF) protein A2 and the IF protein C2 in the nematode Caenorhabditis elegans
Karabinoš, A., Schulze, E., Klisch, T. J., Wang, J., & Weber, K. K. (2002) · Mechanisms of Development · doi:10.1016/s0925-4773(02)00192-2 · Cited by 32
The Caenorhabditis elegans Orthologue of Mammalian Puromycin-sensitive Aminopeptidase Has Roles in Embryogenesis and Reproduction
Brooks, D. R., Hooper, N. M., & Isaac, R. E. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m306216200 · Cited by 32
Immunological detection of alkaline‐diaminobenzidine‐negativeperoxisomes of the nematode Caenorhabditis elegans
Togo, S. H., Maebuchi, M., Yokota, S., Bun‐ya, M., Kawahara, A., & Kamiryo, T. (2000) · European Journal of Biochemistry · doi:10.1046/j.1432-1327.2000.01091.x · Cited by 28
Contribution of the GTPase Domain to the Subcellular Localization of Dynamin in the NematodeCaenorhabditis elegans
Labrousse, A. M., Shurland, D., & van der Bliek, A. M. (1998) · Molecular Biology of the Cell · doi:10.1091/mbc.9.11.3227 · Cited by 26
Calcium feedback mechanisms regulate oscillatory activity of a TRP‐like Ca2+ conductance in C. elegans intestinal cells
Estevez, A. Y., & Strange, K. B. (2005) · The Journal of Physiology · doi:10.1113/jphysiol.2005.091900 · Cited by 25
Complementary expression patterns of six nonessential Caenorhabditis elegans core 2/I N-acetylglucosaminyltransferase homologues
Warren, C. E., Krizus, A., & Dennis, J. W. (2001) · Glycobiology · doi:10.1093/glycob/11.11.979 · Cited by 25
The occurrence of submicrovillar endotube (modified terminal web) and associated cytoskeletal structures in the intestinal epithelia of nematodes
Munn, E. A., & Greenwood, C. A. (1984) · Philosophical transactions of the Royal Society of London. Series B, Biological sciences · doi:10.1098/rstb.1984.0079 · Cited by 23
Proteoglycan Distribution Pattern During Aging in the Nematode Caenorhabditis elegans: An Ultrastructural Histochemical Study
Schimpf, J. H., Sames, K., & Zwilling, R. (1999) · The Histochemical Journal · doi:10.1023/a:1003761817109 · Cited by 17
Peroxisomes of the nematode Caenorhabditis elegans: distribution and morphological characteristics
Yokota, S., Togo, S. H., Maebuchi, M., Bun‐ya, M., Haraguchi, C. M., & Kamiryo, T. (2002) · Histochemistry and Cell Biology · doi:10.1007/s00418-002-0450-y · Cited by 16
IRI-1, a LIN-15B Homologue, Interacts with Inositol-1,4,5-Triphosphate Receptors and Regulates Gonadogenesis, Defecation, and Pharyngeal Pumping inCaenorhabditis elegans
Walker, D. S., Ly, S., Gower, N. J. D., & Baylis, H. A. (2004) · Molecular Biology of the Cell · doi:10.1091/mbc.e04-01-0039 · Cited by 14
A Novel Adapter Protein Employs a Phosphotyrosine Binding Domain and Exceptionally Basic N-terminal Domains to Capture and Localize an Atypical Protein Kinase C
Zhang, L., Wu, S.-L., & Rubin, C. S. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m008990200 · Cited by 11
Functional GATA- and initiator-like-elements exhibit a similar arrangement in the promoters of Caenorhabditis elegans polyamine synthesis enzymes
Lüersen, K., Eschbach, M.-L., Liebau, E., & Walter, R. D. (2004) · Biological Chemistry · doi:10.1515/bc.2004.087 · Cited by 7
The cDNA Sequence and Expression of the AAA-family Peroxin Genespex-1andpex-6from the Nematode Caenorhabditis elegans
Ghenea, S., Takeuchi, M., Motoyama, J., Sasamoto, K., Kunau, W., Kamiryo, T., & Bun‐ya, M. (2001) · ZOOLOGICAL SCIENCE · doi:10.2108/zsj.18.675 · Cited by 3

Distinct Pathogenesis and Host Responses during Infection of C. elegans by P. aeruginosa and S. aureus
Irazoqui, J. E., Troemel, E. R., Feinbaum, R. L., Luhachack, L. G., Cezairliyan, B. O., & Ausubel, F. M. (2010) · PLoS Pathogens · doi:10.1371/journal.ppat.1000982 · Cited by 381
Hg2+ Selective Fluorescent and Colorimetric Sensor: Its Crystal Structure and Application to Bioimaging
Chen, X., Nam, S.-W., Jou, M. J., Kim, Y., Kim, S.-J., Park, S., & Yoon, J. (2008) · Organic Letters · doi:10.1021/ol8022598 · Cited by 301
Cell-type-specific nuclei purification from whole animals for genome-wide expression and chromatin profiling
Steiner, F. A., Talbert, P. B., Kasinathan, S., Deal, R. B., & Henikoff, S. (2012) · Genome Research · doi:10.1101/gr.131748.111 · Cited by 123
ETS-4 Is a Transcriptional Regulator of Life Span in Caenorhabditis elegans
Thyagarajan, B., Blaszczak, A. G., Chandler, K. J., Watts, J. L., Johnson, W. E., & Graves, B. J. (2010) · PLoS Genetics · doi:10.1371/journal.pgen.1001125 · Cited by 51
Knockout of a putative ergothioneine transporter in Caenorhabditis elegans decreases lifespan and increases susceptibility to oxidative damage
Cheah, I. K., Ong, R. L. S., Gruber, J., Yew, T. S. K., Ng, L. F., Chen, C. B., & Halliwell, B. (2013) · Free Radical Research · doi:10.3109/10715762.2013.848354 · Cited by 44

See all 324

Authors: McGhee, J.
Venue: WormBook
Publisher: WormBook
Published: 2007
Pages: 1-36
ISSN: 1551-8507 (ISSN-L)
DOI: 10.1895/wormbook.1.133.1
OpenAlex: W1975539651
Cited by: 324
References: 193
FWCI: 3.38
Type: journal article
Language: en
Open access: hybrid

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