Cited by 110Gut microbiota and healthNutritional Studies and DietDiet, Metabolism, and Disease

Links between Dietary Protein Sources, the Gut Microbiota, and Obesity

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Madsen, Lise, Myrmel, Lene S., Fjære, Even, Liaset, Bjørn, Kristiansen, Karsten·2017·Frontiers in Physiology

Abstract

The association between the gut microbiota and obesity is well documented in both humans and in animal models. It is also demonstrated that dietary factors can change the gut microbiota composition and obesity development. However, knowledge of how diet, metabolism and gut microbiota mutually interact and modulate energy metabolism and obesity development is still limited. Epidemiological studies indicate an association between intake of certain dietary protein sources and obesity. Animal studies confirm that different protein sources vary in their ability to either prevent or induce obesity. Different sources of protein such as beans, vegetables, dairy, seafood, and meat differ in amino acid composition. Further, the type and level of other factors, such as fatty acids and persistent organic pollutants (POPs) vary between dietary protein sources. All these factors can modulate the composition of the gut microbiota and may thereby influence their obesogenic properties. This review summarizes evidence of how different protein sources affect energy efficiency, obesity development, and the gut microbiota, linking protein-dependent changes in the gut microbiota with obesity.

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Crossref · 10.3389/fphys.2017.01047

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  • Numerous studies have shown a strong correlation between protein intake and overall microbial diversity.

    “Numerous studies have shown a strong correlation between protein intake and overall microbial diversity (Madsen et al., 2017).”

    From The Microbiota-Gut-Brain Axis (2019) · cites this paper as Madsen et al., 2017

    The section ‘Protein sources, gut microbiota, and obesity’ (page unavailable) says diet composition affects gut microbial diversity and that protein can affect the gut microbiota. It does not report that numerous studies found a strong correlation specifically between protein intake and overall microbial diversity; it also reports a mouse study in which dietary fat, rather than the protein-to-sucrose ratio, was the major driver of microbiota composition. (LLM, conf=0.87)

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Authors
Madsen, L., Myrmel, L. S., Fjære, E., Liaset, B., & Kristiansen, K.
Affiliations
BGI Group (China) (CN)
Corresponding author
Madsen, Lise
Venue
Frontiers in Physiology
Published
2017-12-19
Volume
8
Pages
1047-1047
ISSN
1664-042X (ISSN-L)
OpenAlex
W2776767255
Cited by
110
References
152
Citations by year
2026: 6 · 2025: 12 · 2024: 11 · 2023: 10 · 2022: 20 · 2021: 19 · 2020: 16 · 2019: 11 · 2018: 5
FWCI
0.82
Type
journal article
Language
en
Open access
Locations
  • Frontiers in Physiology (publishedVersion, cc-by)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • Research at the University of Copenhagen (University of Copenhagen) (publishedVersion, cc-by)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diet, Metabolism, and Disease
Keywords
dietary protein source, gut microbiota, obesity, energy metabolism, amino acid composition, fatty acids, persistent organic pollutants, meat, dairy products, seafood, beans, vegetables, energy efficiency

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