Cited by 72Mindfulness and Compassion InterventionsDementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Meditation as a Therapeutic Intervention for Adults at Risk for Alzheimer’s Disease – Potential Benefits and Underlying Mechanisms

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Innes, Kim E., Selfe, Terry Kit·2014·Frontiers in Psychiatry

Abstract

Alzheimer's disease (AD) is a chronic, progressive, brain disorder that affects at least 5.3 million Americans at an estimated cost of $148 billion, figures that are expected to rise steeply in coming years. Despite decades of research, there is still no cure for AD, and effective therapies for preventing or slowing progression of cognitive decline in at-risk populations remain elusive. Although the etiology of AD remains uncertain, chronic stress, sleep deficits, and mood disturbance, conditions common in those with cognitive impairment, have been prospectively linked to the development and progression of both chronic illness and memory loss and are significant predictors of AD. Therapies such as meditation that specifically target these risk factors may thus hold promise for slowing and possibly preventing cognitive decline in those at risk. In this study, we briefly review the existing evidence regarding the potential utility of meditation as a therapeutic intervention for those with and at risk for AD, discuss possible mechanisms underlying the observed benefits of meditation, and outline directions for future research.

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Authors
Innes, K. E., & Selfe, T. K.
Affiliations
West Virginia University (US)
Corresponding author
Innes, Kim E.
Venue
Frontiers in Psychiatry
Published
2014-04-23
Volume
5
Pages
40-40
ISSN
1664-0640 (ISSN-L)
OpenAlex
W2078228300
Cited by
72
References
174
Citations by year
2026: 3 · 2025: 5 · 2024: 3 · 2022: 9 · 2021: 11 · 2020: 2 · 2019: 5 · 2018: 13 · 2017: 9 · 2016: 4 · 2015: 8
FWCI
8.28
Type
journal article
Language
en
Open access
Licence
cc-by
Locations
  • Frontiers in Psychiatry (publishedVersion, cc-by)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
  • West Virginia University
  • Alzheimer's Research and Prevention Foundation
  • National Institutes of Health
  • National Center for Complementary and Alternative Medicine
Topics
  • Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
  • Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
  • Health Sciences › Medicine › Physiology › Alzheimer's disease research and treatments
Keywords
meditation, Alzheimer's disease, cognitive decline, risk factors, chronic stress, insufficient sleep, mood disturbance, memory loss, therapeutic interventions

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