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Dorsal striatum responses to reward and punishment: Effects of valence and magnitude manipulations
Open accessAbstract
The goal of this research was to further our understanding of how the striatum responds to the delivery of affective feedback. Previously, we had found that the striatum showed a pattern of sustained activation after presentation of a monetary reward, in contrast to a decrease in the hemodynamic response after a punishment. In this study, we tested whether the activity of the striatum could be modulated by parametric variations in the amount of financial reward or punishment. We used an event-related fMRI design in which participants received large or small monetary rewards or punishments after performance in a gambling task. A parametric ordering of conditions was observed in the dorsal striatum according to both magnitude and valence. In addition, an early response to the presentation of feedback was observed and replicated in a second experiment with increased temporal resolution. This study further implicates the dorsal striatum as an integral component of a reward circuitry responsible for the control of motivated behavior, serving to code for such feedback properties as valence and magnitude.
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“The IPS and putamen have both been associated with response planning, oculomotor control (Everling & Munoz, 2000), reward prediction (Peck et al., 2009) and outcome (Delgado et al., 2003).”
From Developmental changes in brain function underlying the influence of reward processing on inhibitory control (2011) · cites this paper as Delgado et al., 2003
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“previous studies have shown that in the context of uncertainty (e.g., gambling task) also the dorsal striatum responds to valence (reward or loss) and magnitude of outcomes, showing strongest activation to large monetary rewards, and weakest activation to large monetary losses (Delgado et al., 2003).”
From Testosterone levels correspond with increased ventral striatum activation in response to monetary rewards in adolescents (2011) · cites this paper as Delgado et al., 2003
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Metadata
- Authors
- DELGADO, M. R., LOCKE, H. M., STENGER, V. A., & FIEZ, J. A.
- Affiliations
- University of Pittsburgh (US)
- Corresponding author
- DELGADO, M. R.
- Venue
- Cognitive, Affective, & Behavioral Neuroscience
- Published
- 2003-03-01
- Volume
- 3
- Issue
- 1
- Pages
- 27-38
- ISSN
- 1530-7026 (ISSN-L)
- 1531-135X
- OpenAlex
- W2128577709
- Cited by
- 431
- References
- 76
- Citations by year
- 2026: 4 · 2025: 8 · 2024: 9 · 2023: 11 · 2022: 11 · 2021: 15 · 2020: 15 · 2019: 20 · 2018: 22 · 2017: 12 · 2016: 17 · 2015: 17 · 2014: 26 · 2013: 35 · 2012: 19
- FWCI
- 7.98
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Cognitive Affective & Behavioral Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Science Foundation (9720350)
- National Institutes of Health
- National Institute on Drug Abuse (R01DA14103, R01DA014103)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Social Sciences › Psychology › Clinical Psychology › Gambling Behavior and Treatments
- Keywords
- dorsal striatum, reward, punishment, emotional feedback, valence, reward magnitude, monetary rewards, gambling task, parametric modulation, motivated behavior, reward systems, hemodynamic response
- MeSH terms
- Adult, Affect, Analysis of Variance, Brain Mapping, Caudate Nucleus, Cerebral Cortex, Corpus Striatum, Evoked Potentials, Female, Humans, Magnetic Resonance Imaging, Male, Motivation, Punishment, Reinforcement, Psychology, Reward, Time Factors, Feedback, Psychological
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